Neurocrine Biosciences Quarterly Balance Sheets Chart
Quarterly
|
Annual
Neurocrine Biosciences Quarterly Balance Sheets Table
Quarterly
|
Annual
| Unit: USD | 2025-06-30 | 2025-03-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | 2017-12-31 | 2017-09-30 | 2017-06-30 | 2017-03-31 | 2016-12-31 | 2016-09-30 | 2016-06-30 | 2016-03-31 | 2015-12-31 | 2015-09-30 | 2015-06-30 | 2015-03-31 | 2014-12-31 | 2014-09-30 | 2014-06-30 | 2014-03-31 | 2013-12-31 | 2013-09-30 | 2013-06-30 | 2013-03-31 | 2012-12-31 | 2012-09-30 | 2012-06-30 | 2012-03-31 | 2011-12-31 | 2011-09-30 | 2011-06-30 | 2011-03-31 | 2010-12-31 | 2010-09-30 | 2010-06-30 | 2010-03-31 | 2009-12-31 | 2009-09-30 | 2009-06-30 | 2009-03-31 | 2008-12-31 | 2008-09-30 | 2008-06-30 | 2008-03-31 | 2007-12-31 | 2007-09-30 | 2007-06-30 | 2007-03-31 | 2006-12-31 | 2006-09-30 | 2006-06-30 | 2006-03-31 | 2005-12-31 | 2005-09-30 | 2005-06-30 | 2005-03-31 | 2004-12-31 | 2004-09-30 | 2004-06-30 | 2004-03-31 | 2003-12-31 | 2003-09-30 | 2003-06-30 | 2003-03-31 | 2002-12-31 | 2002-09-30 | 2002-06-30 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| assets | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| current assets: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| cash and cash equivalents | 264,000,000 | 194,100,000 | 349,100,000 | 139,700,000 | 396,300,000 | 251,100,000 | 293,700,000 | 160,200,000 | 103,800,000 | 262,900,000 | 212,200,000 | 163,300,000 | 270,200,000 | 340,800,000 | 311,100,000 | 368,000,000 | 352,600,000 | 187,100,000 | 425,300,000 | 415,100,000 | 187,000,000 | 112,279,000 | 166,637,000 | 140,985,000 | 72,778,000 | 141,714,000 | 195,734,000 | 166,422,000 | 175,311,000 | 254,712,000 | 267,818,000 | 309,498,000 | 64,087,000 | 83,267,000 | 99,761,000 | 86,246,000 | 115,301,000 | 74,195,000 | 66,378,000 | 132,070,000 | 170,262,000 | 31,014,000 | 29,046,000 | 37,445,000 | 105,532,000 | 44,789,000 | 34,889,000 | 44,313,000 | 31,555,000 | 63,754,000 | 44,488,000 | 42,018,000 | 76,940,000 | 50,107,000 | 39,516,000 | 18,838,000 | 24,393,000 | 54,051,000 | 77,330,000 | 95,120,000 | 52,224,000 | 37,329,000 | 35,316,000 | 38,615,000 | 51,665,000 | 68,467,000 | 80,125,000 | 91,917,000 | 107,639,000 | 99,664,000 | 50,350,000 | 51,485,000 | 78,457,000 | 80,981,000 | 75,760,000 | 86,168,000 | 101,494,000 | 49,948,000 | 75,384,000 | 48,499,000 | 44,570,000 | 61,027,000 | 84,694,000 | 22,735,000 | 38,009,000 | 105,854,000 | 123,820,000 | 34,896,000 | 68,411,000 | 56,626,000 | 47,856,000 | |
| available-for-sale debt securities | 711,600,000 | 749,400,000 | 878,900,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| accounts receivable | 595,700,000 | 516,000,000 | 481,100,000 | 468,200,000 | 450,700,000 | 439,300,000 | 417,800,000 | 387,600,000 | 391,600,000 | 350,000,000 | 301,200,000 | 279,000,000 | 263,500,000 | 185,500,000 | 163,800,000 | 158,500,000 | 147,800,000 | 157,100,000 | 156,900,000 | 148,400,000 | 148,600,000 | 126,575,000 | 115,318,000 | 95,357,000 | 71,964,000 | 56,240,000 | 54,097,000 | 42,646,000 | 44,624,000 | 31,127,000 | 29,818,000 | 6,074,000 | 5,219,000 | 11,280,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| inventory | 56,900,000 | 59,100,000 | 45,800,000 | 42,500,000 | 37,200,000 | 38,300,000 | 30,500,000 | 17,288,000 | 10,798,000 | 12,018,000 | 13,010,000 | 10,864,000 | 6,054,000 | 242,000 | 128,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| other current assets | 120,700,000 | 119,300,000 | 121,700,000 | 120,200,000 | 100,500,000 | 97,800,000 | 108,200,000 | 100,600,000 | 113,200,000 | 79,100,000 | 67,900,000 | 62,700,000 | 60,800,000 | 45,500,000 | 50,500,000 | 38,400,000 | 33,800,000 | 30,100,000 | 34,700,000 | 27,500,000 | 26,700,000 | 16,647,000 | 22,954,000 | 21,455,000 | 24,150,000 | 19,760,000 | 18,900,000 | 16,291,000 | 8,613,000 | 7,863,000 | 7,407,000 | 5,529,000 | 3,871,000 | 3,092,000 | 4,849,000 | 4,568,000 | 4,377,000 | 4,883,000 | 5,940,000 | 4,696,000 | 4,916,000 | 4,394,000 | 4,194,000 | 2,700,000 | 2,232,000 | 2,119,000 | 2,153,000 | 2,162,000 | 2,688,000 | 2,179,000 | 2,079,000 | 1,470,000 | 2,098,000 | 1,966,000 | 1,664,000 | 1,716,000 | 1,402,000 | 1,093,000 | 2,133,000 | 1,923,000 | 1,060,000 | 1,014,000 | 819,000 | 911,000 | 1,698,000 | 1,726,000 | 2,446,000 | 3,536,000 | 3,329,000 | 3,263,000 | 3,248,000 | 3,863,000 | 4,571,000 | 5,902,000 | 4,303,000 | 5,384,000 | 5,252,000 | 5,425,000 | 5,899,000 | 4,473,000 | 4,818,000 | 4,886,000 | 5,354,000 | 4,982,000 | 5,200,000 | 9,263,000 | 3,767,000 | 3,818,000 | 4,406,000 | |||
| total current assets | 1,748,900,000 | 1,637,900,000 | 1,876,600,000 | 1,669,800,000 | 1,799,000,000 | 1,607,000,000 | 1,649,900,000 | 1,496,600,000 | 1,432,800,000 | 1,453,500,000 | 1,205,500,000 | 1,019,300,000 | 1,018,200,000 | 972,800,000 | 1,005,700,000 | 1,110,100,000 | 1,085,400,000 | 1,016,200,000 | 1,156,900,000 | 1,146,200,000 | 968,200,000 | 831,034,000 | 819,232,000 | 748,808,000 | 633,192,000 | 737,777,000 | 714,394,000 | 567,677,000 | 513,716,000 | 554,919,000 | 548,485,000 | 536,751,000 | 239,451,000 | 310,442,000 | 357,891,000 | 391,966,000 | 400,984,000 | 384,074,000 | 382,785,000 | 389,416,000 | 404,953,000 | 198,203,000 | 183,868,000 | 197,575,000 | 221,735,000 | 148,462,000 | 159,218,000 | 155,853,000 | 160,395,000 | 189,264,000 | 178,018,000 | 181,258,000 | 184,974,000 | 132,476,000 | 136,126,000 | 120,038,000 | 126,584,000 | 133,051,000 | 131,592,000 | 143,761,000 | 68,332,000 | 55,387,000 | 58,190,000 | 53,784,000 | 67,204,000 | 81,423,000 | 98,810,000 | 113,629,000 | 152,203,000 | 182,948,000 | 128,180,000 | 150,595,000 | 170,313,000 | 193,658,000 | 204,780,000 | 240,627,000 | 274,722,000 | 279,310,000 | 297,628,000 | 271,525,000 | 281,034,000 | 313,815,000 | 336,658,000 | 336,054,000 | 381,650,000 | |||||||
| deferred tax assets | 536,800,000 | 499,400,000 | 454,400,000 | 419,500,000 | 378,200,000 | 362,600,000 | 383,200,000 | 379,000,000 | 337,400,000 | 305,900,000 | 319,400,000 | 328,400,000 | 325,300,000 | 315,100,000 | 310,400,000 | 316,100,000 | 325,600,000 | 319,400,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| right-of-use assets | 492,300,000 | 502,200,000 | 257,300,000 | 262,900,000 | 270,800,000 | 276,500,000 | 80,800,000 | 83,500,000 | 84,400,000 | 87,000,000 | 89,600,000 | 92,200,000 | 94,700,000 | 97,200,000 | 97,900,000 | 100,300,000 | 97,000,000 | 82,800,000 | 71,000,000 | 72,100,000 | 73,300,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| equity investments | 87,500,000 | 94,200,000 | 126,700,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| property and equipment | 91,700,000 | 87,000,000 | 80,000,000 | 80,100,000 | 75,300,000 | 70,800,000 | 68,800,000 | 65,600,000 | 62,800,000 | 58,600,000 | 60,900,000 | 66,800,000 | 63,900,000 | 58,600,000 | 51,100,000 | 50,000,000 | 45,300,000 | 44,600,000 | 43,000,000 | 44,600,000 | 41,900,000 | 41,914,000 | 40,302,000 | 39,623,000 | 36,661,000 | 33,869,000 | 28,618,000 | 18,775,000 | 11,825,000 | 10,811,000 | 9,140,000 | 6,954,000 | 7,144,000 | 6,271,000 | 6,180,000 | 5,811,000 | 3,897,000 | 3,432,000 | 2,874,000 | 2,802,000 | 2,543,000 | 2,507,000 | 2,292,000 | 2,239,000 | 1,798,000 | 1,771,000 | 1,739,000 | 1,876,000 | 1,784,000 | 1,900,000 | 2,034,000 | 1,861,000 | 1,837,000 | 1,586,000 | 1,687,000 | 1,263,000 | 1,309,000 | 1,532,000 | 1,827,000 | 2,085,000 | 2,236,000 | 2,695,000 | 3,395,000 | 4,183,000 | 5,075,000 | 6,191,000 | 77,309,000 | 79,434,000 | 80,672,000 | 82,598,000 | 84,631,000 | 86,524,000 | 88,882,000 | 91,378,000 | 93,868,000 | 96,693,000 | 97,363,000 | 99,307,000 | 98,937,000 | 99,811,000 | 101,238,000 | 102,166,000 | 98,985,000 | 93,957,000 | 79,044,000 | 56,236,000 | 58,289,000 | 48,407,000 | 14,372,000 | 14,102,000 | 13,708,000 | 13,037,000 |
| intangible assets | 37,200,000 | 36,400,000 | 34,500,000 | 33,500,000 | 34,300,000 | 35,500,000 | 34,900,000 | 36,900,000 | 37,200,000 | 37,200,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| other noncurrent assets | 21,600,000 | 15,300,000 | 61,600,000 | 57,800,000 | 50,900,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| total assets | 3,889,800,000 | 3,687,700,000 | 3,535,000,000 | 3,305,000,000 | 3,472,400,000 | 3,251,400,000 | 2,848,200,000 | 2,613,100,000 | 2,359,800,000 | 2,368,700,000 | 2,143,400,000 | 2,005,700,000 | 2,144,500,000 | 2,072,500,000 | 2,017,300,000 | 1,956,400,000 | 1,846,400,000 | 1,734,700,000 | 1,502,600,000 | 1,515,600,000 | 1,361,900,000 | 1,306,040,000 | 1,179,935,000 | 1,066,861,000 | 957,723,000 | 993,151,000 | 933,746,000 | 841,317,000 | 806,360,000 | 817,591,000 | 772,496,000 | 754,086,000 | 289,364,000 | 365,086,000 | 399,161,000 | 429,838,000 | 459,332,000 | 474,785,000 | 492,436,000 | 511,205,000 | 527,779,000 | 243,033,000 | 257,751,000 | 269,539,000 | 279,296,000 | 154,676,000 | 165,967,000 | 174,813,000 | 183,924,000 | 195,979,000 | 193,251,000 | 202,087,000 | 210,141,000 | 138,368,000 | 149,028,000 | 127,405,000 | 133,997,000 | 144,424,000 | 149,933,000 | 155,044,000 | 79,883,000 | 70,818,000 | 75,908,000 | 86,869,000 | 101,028,000 | 118,182,000 | 207,733,000 | 225,670,000 | 243,884,000 | 276,654,000 | 317,498,000 | 341,864,000 | 363,715,000 | 389,677,000 | 404,131,000 | 442,543,000 | 477,403,000 | 483,123,000 | 500,969,000 | 475,512,000 | 486,368,000 | 519,217,000 | 552,619,000 | 546,479,000 | 577,269,000 | |||||||
| liabilities and stockholders' equity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| current liabilities: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| accounts payable and accrued liabilities | 489,500,000 | 475,200,000 | 392,700,000 | 358,500,000 | 417,200,000 | 448,800,000 | 503,000,000 | 391,600,000 | 355,700,000 | 347,600,000 | 297,800,000 | 265,700,000 | 235,900,000 | 225,800,000 | 205,900,000 | 190,900,000 | 171,900,000 | 168,700,000 | 170,500,000 | 137,100,000 | 125,900,000 | 141,285,000 | 102,357,000 | 95,027,000 | 68,280,000 | 86,377,000 | 72,022,000 | 61,031,000 | 45,650,000 | 53,520,000 | 37,289,000 | 26,809,000 | 17,294,000 | 15,663,000 | 13,910,000 | 15,428,000 | 17,233,000 | 16,791,000 | 18,091,000 | 17,716,000 | 18,733,000 | 29,573,000 | 27,119,000 | |||||||||||||||||||||||||||||||||||||||||||||||||
| other current liabilities | 56,800,000 | 47,700,000 | 37,000,000 | 40,000,000 | 36,700,000 | 35,900,000 | 18,700,000 | 21,200,000 | 18,400,000 | 20,700,000 | 18,100,000 | 20,000,000 | 17,600,000 | 20,000,000 | 20,000,000 | 22,000,000 | 18,100,000 | 17,800,000 | 15,500,000 | 16,400,000 | 14,400,000 | 15,195,000 | 13,295,000 | 5,562,000 | 3,723,000 | 1,856,000 | 731,000 | 731,000 | 85,000 | 113,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| total current liabilities | 546,300,000 | 522,900,000 | 429,700,000 | 398,500,000 | 712,900,000 | 654,800,000 | 691,600,000 | 582,500,000 | 374,100,000 | 537,700,000 | 485,100,000 | 285,700,000 | 253,500,000 | 245,800,000 | 225,900,000 | 212,900,000 | 190,000,000 | 186,500,000 | 611,000,000 | 573,000,000 | 140,300,000 | 565,287,000 | 115,652,000 | 100,589,000 | 72,003,000 | 88,233,000 | 456,400,000 | 61,762,000 | 46,466,000 | 54,426,000 | 38,141,000 | 27,721,000 | 23,563,000 | 30,414,000 | 26,666,000 | 26,899,000 | 23,276,000 | 25,715,000 | 19,822,000 | 17,553,000 | 15,187,000 | 15,664,000 | 14,045,000 | 12,053,000 | 10,608,000 | 11,699,000 | 13,321,000 | 14,573,000 | 13,878,000 | 15,646,000 | 23,113,000 | 29,152,000 | 36,631,000 | 47,110,000 | 48,444,000 | 49,990,000 | 49,028,000 | 52,777,000 | 53,184,000 | 52,123,000 | 18,630,000 | 19,961,000 | 24,044,000 | 33,017,000 | 32,536,000 | 26,094,000 | 18,975,000 | 19,494,000 | 17,972,000 | 29,907,000 | 20,021,000 | 18,943,000 | 17,823,000 | 20,116,000 | 21,267,000 | 23,932,000 | 32,757,000 | 33,693,000 | 35,039,000 | 40,294,000 | 47,182,000 | 59,585,000 | 72,112,000 | 67,503,000 | 97,536,000 | |||||||
| noncurrent operating lease liabilities | 439,100,000 | 447,500,000 | 251,400,000 | 256,200,000 | 252,900,000 | 258,300,000 | 85,900,000 | 89,100,000 | 90,400,000 | 93,500,000 | 105,300,000 | 94,400,000 | 86,756,000 | 74,482,000 | 66,185,000 | 67,147,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| other noncurrent liabilities | 210,100,000 | 181,600,000 | 135,000,000 | 141,100,000 | 120,500,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| total liabilities | 1,195,500,000 | 1,152,000,000 | 816,100,000 | 795,800,000 | 1,086,300,000 | 1,019,400,000 | 846,100,000 | 760,100,000 | 675,300,000 | 660,900,000 | 598,800,000 | 582,300,000 | 753,400,000 | 698,500,000 | 671,300,000 | 677,200,000 | 640,800,000 | 608,500,000 | 698,300,000 | 684,400,000 | 661,600,000 | 669,117,000 | 605,420,000 | 583,155,000 | 548,448,000 | 512,386,000 | 486,233,000 | 463,881,000 | 441,873,000 | 445,453,000 | 424,984,000 | 408,848,000 | 42,223,000 | 50,209,000 | 47,510,000 | 48,800,000 | 46,373,000 | 50,331,000 | 45,493,000 | 44,265,000 | 43,049,000 | 34,334,000 | 33,714,000 | 32,694,000 | 32,239,000 | 34,266,000 | 36,675,000 | 38,797,000 | 38,971,000 | 41,607,000 | 49,946,000 | 57,354,000 | 66,307,000 | 78,287,000 | 91,279,000 | 101,847,000 | 111,003,000 | 125,079,000 | 133,286,000 | 142,632,000 | 63,162,000 | 66,864,000 | 74,833,000 | 79,521,000 | 81,917,000 | 81,408,000 | 144,086,000 | 145,829,000 | 145,218,000 | 157,957,000 | 72,544,000 | 72,815,000 | 72,012,000 | 74,961,000 | 77,655,000 | 80,771,000 | 93,573,000 | 93,019,000 | 97,229,000 | 103,493,000 | 111,648,000 | 125,390,000 | 140,055,000 | 134,938,000 | 151,864,000 | |||||||
| stockholders’ equity: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| preferred stock, 0.001 par value; 5.0 shares authorized; no shares issued and outstanding | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| common stock | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 92,000 | 92,000 | 92,000 | 91,000 | 91,000 | 91,000 | 90,000 | 90,000 | 89,000 | 88,000 | 88,000 | 88,000 | 87,000 | 87,000 | 87,000 | 87,000 | 86,000 | 86,000 | 86,000 | 85,000 | 76,000 | 76,000 | 76,000 | 76,000 | 67,000 | 67,000 | 67,000 | 67,000 | 66,000 | 66,000 | 66,000 | 66,000 | 55,000 | 55,000 | 55,000 | 55,000 | 55,000 | 55,000 | 55,000 | 55,000 | 44,000 | 39,000 | 39,000 | 39,000 | 39,000 | 39,000 | 38,000 | 38,000 | 38,000 | 38,000 | 38,000 | 38,000 | 38,000 | 38,000 | 38,000 | 38,000 | 37,000 | 37,000 | 37,000 | 37,000 | 37,000 | 36,000 | 36,000 | 36,000 | |||||||
| additional paid-in capital | 2,597,200,000 | 2,531,900,000 | 2,623,200,000 | 2,555,300,000 | 2,496,400,000 | 2,382,000,000 | 2,308,500,000 | 2,241,900,000 | 2,170,500,000 | 2,122,400,000 | 2,054,300,000 | 1,999,800,000 | 1,947,700,000 | 2,011,400,000 | 1,974,000,000 | 1,929,400,000 | 1,897,800,000 | 1,849,700,000 | 1,874,300,000 | 1,842,200,000 | 1,796,900,000 | 1,768,118,000 | 1,739,517,000 | 1,703,458,000 | 1,681,244,000 | 1,660,361,000 | 1,645,311,000 | 1,626,752,000 | 1,608,778,000 | 1,572,765,000 | 1,553,718,000 | 1,540,498,000 | 1,381,938,000 | 1,371,432,000 | 1,363,416,000 | 1,355,768,000 | 1,347,558,000 | 1,340,579,000 | 1,333,385,000 | 1,318,742,000 | 1,312,321,000 | 1,035,205,000 | 1,031,029,000 | 1,027,881,000 | 1,024,780,000 | 886,101,000 | 884,355,000 | 879,983,000 | 876,678,000 | 873,981,000 | 872,383,000 | 870,895,000 | 869,479,000 | 784,811,000 | 783,882,000 | 782,933,000 | 782,376,000 | 781,607,000 | 780,652,000 | 779,755,000 | 778,909,000 | 757,002,000 | 746,178,000 | 744,479,000 | 743,438,000 | 741,568,000 | 739,761,000 | 738,011,000 | 735,731,000 | 733,542,000 | 730,386,000 | 727,812,000 | 724,412,000 | 721,930,000 | 719,405,000 | 716,540,000 | 711,023,000 | 691,717,000 | 682,339,000 | 676,682,000 | 674,925,000 | 674,034,000 | 671,543,000 | 670,183,000 | 668,713,000 | 622,526,000 | 620,724,000 | 432,279,000 | 428,286,000 | 422,205,000 | 421,507,000 | |
| accumulated other comprehensive income | 12,500,000 | 9,000,000 | 14,500,000 | 2,500,000 | 3,300,000 | 7,000,000 | -1,700,000 | 400,000 | 700,000 | 1,000,000 | 1,800,000 | 3,200,000 | 4,600,000 | -1,400,000 | 1,413,000 | 1,606,000 | 645,000 | 19,000 | 696,000 | 691,000 | 694,000 | 1,243,000 | -1,510,000 | -233,000 | 272,000 | 634,000 | 324,000 | 99,000 | -1,908,000 | -1,112,000 | -2,296,000 | 2,024,000 | 1,664,000 | 2,544,000 | 4,416,000 | 3,544,000 | 2,372,000 | 461,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
| retained earnings | 84,500,000 | 81,100,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| total stockholders’ equity | 2,694,300,000 | 2,535,700,000 | 2,718,900,000 | 2,509,200,000 | 2,386,100,000 | 2,232,000,000 | 2,002,100,000 | 1,853,000,000 | 1,684,500,000 | 1,707,800,000 | 1,544,600,000 | 1,423,400,000 | 1,391,100,000 | 1,374,000,000 | 1,346,000,000 | 1,279,200,000 | 1,205,600,000 | 1,126,200,000 | 804,300,000 | 831,200,000 | 700,300,000 | 636,923,000 | 574,515,000 | 483,706,000 | 409,275,000 | 480,765,000 | 447,513,000 | 377,436,000 | 364,487,000 | 372,138,000 | 347,512,000 | 345,238,000 | 247,141,000 | 314,877,000 | 351,651,000 | 381,038,000 | 412,959,000 | 424,454,000 | 446,943,000 | 466,940,000 | 484,730,000 | 208,699,000 | 224,037,000 | 236,845,000 | 247,057,000 | 120,410,000 | 129,292,000 | 136,016,000 | 144,953,000 | 154,372,000 | 143,305,000 | 144,733,000 | 143,834,000 | 60,081,000 | 57,749,000 | 25,558,000 | 22,994,000 | 19,345,000 | 16,647,000 | 12,412,000 | 16,721,000 | 3,954,000 | 1,075,000 | 7,348,000 | 19,111,000 | 36,774,000 | 63,647,000 | 79,841,000 | 98,666,000 | 118,697,000 | 244,954,000 | 269,049,000 | 291,703,000 | 314,716,000 | 326,476,000 | 361,772,000 | 383,830,000 | 390,104,000 | 403,740,000 | 372,019,000 | 374,720,000 | 393,827,000 | 412,564,000 | 411,541,000 | 425,405,000 | |||||||
| total liabilities and stockholders’ equity | 3,889,800,000 | 3,687,700,000 | 3,535,000,000 | 3,305,000,000 | 3,472,400,000 | 3,251,400,000 | 2,848,200,000 | 2,613,100,000 | 2,359,800,000 | 2,368,700,000 | 2,143,400,000 | 2,005,700,000 | 2,144,500,000 | 2,072,500,000 | 2,017,300,000 | 1,956,400,000 | 1,846,400,000 | 1,734,700,000 | 1,502,600,000 | 1,515,600,000 | 1,361,900,000 | 1,306,040,000 | 1,179,935,000 | 1,066,861,000 | 957,723,000 | 993,151,000 | 933,746,000 | 841,317,000 | 806,360,000 | 817,591,000 | 772,496,000 | 754,086,000 | 289,364,000 | 365,086,000 | 399,161,000 | 429,838,000 | 459,332,000 | 474,785,000 | 492,436,000 | 511,205,000 | 527,779,000 | 243,033,000 | 257,751,000 | 269,539,000 | 279,296,000 | 154,676,000 | 165,967,000 | 174,813,000 | 183,924,000 | 195,979,000 | 193,251,000 | 202,087,000 | 210,141,000 | 138,368,000 | 149,028,000 | 127,405,000 | 133,997,000 | 144,424,000 | 149,933,000 | 155,044,000 | 79,883,000 | 70,818,000 | 75,908,000 | 86,869,000 | 101,028,000 | 118,182,000 | 207,733,000 | 225,670,000 | 243,884,000 | 276,654,000 | 317,498,000 | 341,864,000 | 363,715,000 | 389,677,000 | 404,131,000 | 442,543,000 | 477,403,000 | 483,123,000 | 500,969,000 | 475,512,000 | 486,368,000 | 519,217,000 | 552,619,000 | 546,479,000 | 577,269,000 | |||||||
| (accumulated deficit) retained earnings | -5,300,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| convertible senior notes | 170,100,000 | 169,900,000 | 169,700,000 | 169,400,000 | 169,200,000 | 169,000,000 | 377,700,000 | 335,100,000 | 330,700,000 | 326,300,000 | 322,000,000 | 425,000,000 | 419,500,000 | 408,807,000 | 403,589,000 | 398,466,000 | 393,435,000 | 388,496,000 | 378,885,000 | 374,209,000 | 369,618,000 | 365,110,000 | 360,681,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| debt securities available-for-sale | 899,200,000 | 814,300,000 | 780,500,000 | 801,400,000 | 816,500,000 | 790,800,000 | 726,400,000 | 587,200,000 | 485,000,000 | 394,700,000 | 370,500,000 | 613,900,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| equity security investments | 143,600,000 | 163,500,000 | 132,800,000 | 173,000,000 | 135,700,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| accumulated deficit | -48,700,000 | -113,700,000 | -157,100,000 | -304,800,000 | -387,900,000 | -483,400,000 | -406,800,000 | -495,800,000 | -564,300,000 | -547,400,000 | -635,800,000 | -628,500,000 | -651,000,000 | -693,300,000 | -725,400,000 | -1,073,300,000 | -1,015,700,000 | -1,095,300,000 | -1,132,700,000 | -1,166,700,000 | -1,220,489,000 | -1,271,827,000 | -1,177,755,000 | -1,195,833,000 | -1,246,597,000 | -1,240,684,000 | -1,198,866,000 | -1,205,760,000 | -1,194,635,000 | -1,134,650,000 | -1,056,324,000 | -1,011,665,000 | -974,778,000 | -934,498,000 | -915,234,000 | -885,919,000 | -851,484,000 | -827,497,000 | -826,305,000 | -806,861,000 | -790,986,000 | -777,605,000 | -765,763,000 | -755,121,000 | -743,990,000 | -731,748,000 | -719,673,000 | -729,163,000 | -726,085,000 | -725,584,000 | -724,698,000 | -726,029,000 | -757,411,000 | -759,387,000 | -762,269,000 | -764,756,000 | -768,089,000 | -762,937,000 | -754,301,000 | -746,385,000 | -738,208,000 | -722,928,000 | -703,263,000 | -674,409,000 | -656,698,000 | -635,727,000 | -614,650,000 | -486,675,000 | -459,435,000 | -433,071,000 | -407,351,000 | -392,639,000 | -353,496,000 | -326,047,000 | -300,146,000 | -276,238,000 | -302,389,000 | -296,785,000 | -277,955,000 | -257,340,000 | -255,693,000 | -244,562,000 | -232,182,000 | -235,375,000 | -225,541,000 | -215,316,000 | -163,139,000 | -142,905,000 | ||||
| convertible senior notes, at carrying value | 122,800,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| convertible senior notes embedded derivative liability | 136,200,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| preferred stock, 0.001 par value; 5.0 million shares authorized; no shares issued and outstanding | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| equity securities | 161,900,000 | 102,100,000 | 94,900,000 | 83,800,000 | 91,300,000 | 63,700,000 | 35,300,000 | 38,900,000 | 38,900,000 | 38,200,000 | 43,700,000 | 50,700,000 | 39,400,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| other assets | 49,600,000 | 43,100,000 | 35,900,000 | 24,900,000 | 25,000,000 | 10,500,000 | 10,000,000 | 10,100,000 | 3,200,000 | 3,200,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| liabilities and stockholders’ equity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| other long-term liabilities | 106,300,000 | 68,600,000 | 88,500,000 | 41,300,000 | 29,700,000 | 17,100,000 | 28,000,000 | 19,700,000 | 12,300,000 | 8,300,000 | 29,000,000 | 21,300,000 | 9,700,000 | 4,300,000 | 27,100,000 | 21,600,000 | 17,074,000 | 11,697,000 | 17,915,000 | 15,863,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| inventories | 28,800,000 | 31,700,000 | 33,400,000 | 35,100,000 | 37,000,000 | 29,300,000 | 29,000,000 | 25,500,000 | 28,300,000 | 30,100,000 | 28,000,000 | 20,600,000 | 22,000,000 | 21,200,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| accumulated other comprehensive loss | -1,700,000 | -1,100,000 | -2,700,000 | -7,900,000 | -14,000,000 | -12,200,000 | -9,300,000 | -233,000 | -1,932,000 | -2,056,000 | -2,809,000 | -3,697,000 | -1,850,000 | -534,000 | -713,000 | -235,000 | -318,000 | -187,000 | -39,000 | -188,000 | -977,000 | -609,000 | -404,000 | -179,000 | -9,000 | -44,000 | -44,000 | -2,000 | -143,000 | -127,000 | -87,000 | -159,000 | -19,000 | -50,000 | -1,438,000 | -1,570,000 | -1,744,000 | -1,376,000 | -328,000 | -1,310,000 | -1,184,000 | -1,504,000 | -2,329,000 | -2,147,000 | -3,190,000 | |||||||||||||||||||||||||||||||||||||||||||||||
| operating lease liabilities | 96,600,000 | 99,600,000 | 102,500,000 | 106,400,000 | 109,000,000 | 107,500,000 | 83,000,000 | 84,300,000 | 85,600,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| preferred stock, 0.001 par value; 5.0 million shares authorized; no shares issued and outstanding at march 31, 2022 and december 31, 2021 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| other long-term assets | 4,400,000 | 1,400,000 | 3,200,000 | 3,400,000 | 3,600,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| preferred stock, 0.001 par value; 5.0 shares authorized; no shares issued and outstanding as of december 31, 2021 and 2020 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| debt securities available-for-sale, at fair value | 454,800,000 | 516,900,000 | 521,100,000 | 519,400,000 | 533,200,000 | 584,700,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| preferred stock, 0.001 par value; 5.0 shares authorized; no shares issued and outstanding at september 30, 2021 and december 31, 2020 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| preferred stock, 0.001 par value; 5.0 shares authorized; no shares issued and outstanding at june 30, 2021 and december 31, 2020 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| restricted cash | 3,200,000 | 3,200,000 | 3,200,000 | 3,200,000 | 3,200,000 | 3,206,000 | 4,706,000 | 5,477,000 | 5,477,000 | 5,477,000 | 5,477,000 | 5,477,000 | 4,500,000 | 4,500,000 | 4,613,000 | 4,613,000 | 5,083,000 | 4,883,000 | 4,883,000 | 4,883,000 | 4,991,000 | 4,791,000 | 4,791,000 | 4,815,000 | 4,831,000 | 4,831,000 | 4,443,000 | 4,443,000 | 4,443,000 | 4,443,000 | 4,335,000 | 4,335,000 | 4,335,000 | 4,335,000 | 4,334,000 | 4,334,000 | 4,306,000 | 4,306,000 | 6,128,000 | 6,104,000 | 6,104,000 | 6,102,000 | 6,333,000 | 6,329,000 | 6,327,000 | 6,325,000 | 6,322,000 | 6,414,000 | 6,404,000 | 6,409,000 | 6,441,000 | 6,568,000 | 6,415,000 | 6,399,000 | 5,250,000 | 5,250,000 | 5,250,000 | 5,250,000 | 5,775,000 | 5,775,000 | 5,775,000 | 5,775,000 | 5,775,000 | 5,775,000 | 5,775,000 | |||||||||||||||||||||||||||
| preferred stock, 0.001 par value; 5.0 shares authorized; no shares issued and outstanding at march 31, 2021 and december 31, 2020 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| preferred stock, 0.001 par value; 5.0 shares authorized; no shares issued and outstanding at december 31, 2020 and 2019 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| preferred stock, 0.001 par value; 5.0 shares authorized; no shares issued and outstanding at september 30, 2020 and december 31, 2019 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| preferred stock, 0.001 par value; 5.0 shares authorized; no shares issued and outstanding at june 30, 2020 and december 31, 2019 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| blank | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| preferred stock, 0.001 par value; 5.0 shares authorized; no shares issued and outstanding at march 31, 2020 and december 31, 2019 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| marketable securities | 558,245,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| operating lease assets | 74,364,000 | 61,987,000 | 49,085,000 | 49,304,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| restricted equity securities | 55,868,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| preferred stock, 0.001 par value; 5,000 shares authorized; no shares issued and outstanding | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| short-term investments in available-for-sale debt securities | 503,525,000 | 478,993,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| long-term investments in available-for-sale debt securities | 204,793,000 | 146,503,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| investment in restricted equity securities | 48,915,000 | 77,365,000 | 56,400,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| deferred rent | 18,114,000 | 12,107,000 | 5,326,000 | 3,107,000 | 3,135,000 | 3,163,000 | 1,693,000 | 1,305,000 | 1,462,000 | 1,590,000 | 1,704,000 | 1,817,000 | 1,711,000 | 1,789,000 | 1,852,000 | 1,817,000 | 1,877,000 | 1,916,000 | 1,942,000 | 1,988,000 | 1,982,000 | 1,955,000 | 1,916,000 | 1,878,000 | 1,840,000 | 2,023,000 | 1,959,000 | 1,880,000 | 1,800,000 | 1,698,000 | 1,628,000 | 1,512,000 | 1,413,000 | 1,425,000 | 1,252,000 | 1,079,000 | 906,000 | 706,000 | 756,000 | 433,000 | 110,000 | 2,740,000 | 2,645,000 | 2,551,000 | 2,438,000 | |||||||||||||||||||||||||||||||||||||||||||||||
| deferred gain on sale of real estate | 7,312,000 | 7,495,000 | 7,677,000 | 7,860,000 | 8,043,000 | 8,226,000 | 8,409,000 | 6,467,000 | 7,372,000 | 8,261,000 | 9,140,000 | 10,019,000 | 10,898,000 | 11,761,000 | 12,614,000 | 13,468,000 | 14,322,000 | 15,159,000 | 15,988,000 | 16,817,000 | 17,645,000 | 18,458,000 | 19,263,000 | 20,067,000 | 20,872,000 | 21,661,000 | 22,442,000 | 23,224,000 | 24,005,000 | 24,771,000 | 25,529,000 | 26,288,000 | 27,046,000 | 27,790,000 | 28,527,000 | 29,263,000 | 29,999,000 | 30,721,000 | 31,436,000 | 32,151,000 | 32,867,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| short-term investments, available for sale | 451,290,000 | 439,609,000 | 342,318,000 | 285,168,000 | 171,493,000 | 253,281,000 | 301,152,000 | 266,223,000 | 310,467,000 | 252,650,000 | 199,745,000 | 150,628,000 | 157,211,000 | 114,330,000 | 122,022,000 | 109,383,000 | 126,679,000 | 129,473,000 | 135,522,000 | 104,146,000 | 72,115,000 | 96,322,000 | 97,246,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| long-term investments, available for sale | 176,689,000 | 185,257,000 | 249,388,000 | 276,319,000 | 37,686,000 | 30,207,000 | 27,178,000 | 49,460,000 | 101,986,000 | 114,172,000 | 115,452,000 | 67,148,000 | 65,282,000 | 51,320,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| short-term investments, available-for-sale | 509,199,000 | 261,217,000 | 243,200,000 | 215,522,000 | 224,083,000 | 304,996,000 | 162,795,000 | 100,950,000 | 109,259,000 | 78,996,000 | 72,814,000 | 16,135,000 | 14,152,000 | 14,710,000 | 12,006,000 | 16,824,000 | 19,984,000 | 42,106,000 | 79,721,000 | 74,483,000 | 95,812,000 | 88,334,000 | 101,623,000 | 124,018,000 | 148,151,000 | 162,995,000 | 223,120,000 | 215,454,000 | 194,769,000 | 226,337,000 | 240,102,000 | 239,653,000 | 303,802,000 | 333,724,000 | 347,314,000 | 318,957,000 | 237,918,000 | 239,828,000 | 218,281,000 | 239,614,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| long-term investments, available-for-sale | 216,028,000 | 247,361,000 | 210,258,000 | 205,768,000 | 43,490,000 | 82,488,000 | 37,492,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| deferred revenue | 10,231,000 | 10,231,000 | 10,231,000 | 10,231,000 | 10,231,000 | 10,231,000 | 10,231,000 | 10,231,000 | 10,231,000 | 10,231,000 | 10,231,000 | 10,231,000 | 10,231,000 | 10,231,000 | 10,231,000 | 10,231,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| commitments and contingencies | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| preferred stock, 0.001 par value; 5,000,000 shares authorized; no shares issued and outstanding | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| current portion of convertible senior notes | 383,647,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| current portion of cease-use liability | 62,000 | 121,000 | 181,000 | 243,000 | 236,000 | 265,000 | 259,000 | 234,000 | 428,000 | 481,000 | 556,000 | 479,000 | 467,000 | 454,000 | 441,000 | 428,000 | 416,000 | 409,000 | 402,000 | 496,000 | 589,000 | 280,000 | 273,000 | 269,000 | 264,000 | 1,604,000 | 2,004,000 | 2,701,000 | 3,385,000 | 4,047,000 | 4,450,000 | 4,369,000 | 4,289,000 | 8,898,000 | 15,414,000 | 15,202,000 | 7,870,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
| current portion of deferred gain on sale of real estate | 731,000 | 731,000 | 731,000 | 731,000 | 3,552,000 | 3,526,000 | 3,500,000 | 3,475,000 | 3,449,000 | 3,423,000 | 3,398,000 | 3,373,000 | 3,348,000 | 3,324,000 | 3,299,000 | 3,275,000 | 3,251,000 | 3,227,000 | 3,203,000 | 3,179,000 | 3,156,000 | 3,133,000 | 3,110,000 | 3,087,000 | 3,064,000 | 3,042,000 | 3,019,000 | 2,997,000 | 2,975,000 | 2,953,000 | 2,931,000 | 2,910,000 | 2,888,000 | 2,867,000 | 2,846,000 | 2,826,000 | 2,805,000 | 2,784,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
| current portion of deferred rent | 513,000 | 470,000 | 428,000 | 386,000 | 345,000 | 269,000 | 232,000 | 197,000 | 152,000 | 119,000 | 85,000 | 52,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| cease-use liability | 544,000 | 617,000 | 649,000 | 713,000 | 809,000 | 1,555,000 | 1,670,000 | 1,770,000 | 2,086,000 | 2,211,000 | 2,334,000 | 2,451,000 | 2,566,000 | 2,680,000 | 2,789,000 | 2,893,000 | 2,996,000 | 3,097,000 | 2,269,000 | 2,190,000 | 2,259,000 | 2,328,000 | 5,335,000 | 5,704,000 | 6,150,000 | 6,580,000 | 4,487,000 | 5,093,000 | 6,163,000 | 7,241,000 | 8,378,000 | 2,750,000 | 3,016,000 | 7,527,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| other liabilities | 113,000 | 113,000 | 113,000 | 113,000 | 113,000 | 113,000 | 221,000 | 221,000 | 220,000 | 245,000 | 260,000 | 260,000 | 260,000 | 260,000 | 260,000 | 260,000 | 152,000 | 152,000 | 152,000 | 152,000 | 152,000 | 151,000 | 124,000 | 125,000 | 124,000 | 101,000 | 101,000 | 1,481,000 | 1,436,000 | 1,498,000 | 1,346,000 | 2,835,000 | 3,134,000 | 3,961,000 | 4,455,000 | 4,636,000 | 4,710,000 | 5,085,000 | 5,939,000 | 5,663,000 | 5,693,000 | 6,259,000 | 5,634,000 | 8,413,000 | 5,736,000 | 5,249,000 | 4,799,000 | 4,516,000 | 4,353,000 | 3,997,000 | 3,989,000 | 3,936,000 | 3,109,000 | 2,009,000 | 1,845,000 | 1,534,000 | 1,051,000 | 972,000 | 1,176,000 | |||||||||||||||||||||||||||||||||
| accounts payable | 852,000 | 5,085,000 | 1,719,000 | 1,762,000 | 2,122,000 | 2,561,000 | 1,197,000 | 1,035,000 | 1,270,000 | 246,000 | 900,000 | 846,000 | 818,000 | 101,000 | 1,097,000 | 1,348,000 | 1,460,000 | 911,000 | 1,416,000 | 1,420,000 | 596,000 | 1,111,000 | 766,000 | 932,000 | 507,000 | 810,000 | 912,000 | 640,000 | 539,000 | 2,188,000 | 1,501,000 | 1,752,000 | 2,551,000 | 1,599,000 | 2,988,000 | 2,739,000 | 1,408,000 | 3,776,000 | 3,213,000 | 3,447,000 | 5,391,000 | 2,910,000 | 1,295,000 | 1,912,000 | 2,717,000 | 2,163,000 | 3,669,000 | 1,445,000 | ||||||||||||||||||||||||||||||||||||||||||||
| accrued liabilities | 18,403,000 | 21,097,000 | 20,754,000 | 21,017,000 | 17,126,000 | 19,034,000 | 14,514,000 | 12,392,000 | 9,938,000 | 11,508,000 | 9,307,000 | 7,439,000 | 6,111,000 | 7,955,000 | 7,882,000 | 8,185,000 | 6,577,000 | 8,094,000 | 8,130,000 | 6,937,000 | 6,967,000 | 8,451,000 | 7,562,000 | 7,314,000 | 5,887,000 | 8,603,000 | 8,334,000 | 7,172,000 | 6,428,000 | 6,240,000 | 7,870,000 | 10,104,000 | 9,056,000 | 10,905,000 | 12,785,000 | 13,235,000 | 12,620,000 | 21,717,000 | 12,414,000 | 17,895,000 | 19,846,000 | 42,676,000 | 55,091,000 | 58,524,000 | 47,968,000 | 34,602,000 | 15,504,000 | 17,604,000 | ||||||||||||||||||||||||||||||||||||||||||||
| receivables under collaboration agreements | 15,083,000 | 30,030,000 | 75,000 | 38,000 | 8,000 | 1,369,000 | 1,539,000 | 1,809,000 | 22,397,000 | 2,912,000 | 3,281,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| accumulated other comprehensive gain | -277,000 | -207,000 | -126,000 | -194,000 | 5,000 | -48,000 | 1,209,000 | 1,038,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| receivables under collaboration agreements and other current assets | 2,919,000 | 1,873,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| receivables under collaborative agreements | 23,000 | 14,089,000 | 1,903,000 | 4,470,000 | 12,000 | 3,000 | 10,000 | 39,000 | 163,000 | 2,000 | 12,000 | 27,000 | 18,000 | 35,000 | 274,000 | 7,191,000 | 431,000 | 406,000 | 5,930,000 | 858,000 | 1,538,000 | 22,832,000 | 4,228,000 | 8,213,000 | 7,493,000 | 4,631,000 | 4,563,000 | 13,659,000 | 16,397,000 | 32,221,000 | 29,803,000 | 2,391,000 | 2,722,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| long-term investments | 675,000 | 12,749,000 | 17,410,000 | 480,000 | 8,865,000 | 14,634,000 | 19,024,000 | 5,087,000 | 3,739,000 | 10,181,000 | 2,869,000 | 2,988,000 | 6,411,000 | 6,602,000 | 21,242,000 | 19,609,000 | 21,057,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| current portion of deferred revenues | 730,000 | 1,459,000 | 2,189,000 | 2,919,000 | 10,177,000 | 17,435,000 | 25,735,000 | 34,242,000 | 35,493,000 | 36,743,000 | 36,958,000 | 37,026,000 | 36,960,000 | 36,951,000 | 2,925,000 | 2,941,000 | 2,929,000 | 2,921,000 | 2,922,000 | 2,936,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| deferred revenues | 728,000 | 1,460,000 | 2,189,000 | 2,919,000 | 10,907,000 | 18,895,000 | 27,924,000 | 37,162,000 | 46,400,000 | 55,637,000 | 8,027,000 | 8,757,000 | 9,486,000 | 10,216,000 | 10,946,000 | 11,676,000 | 2,926,000 | 2,919,000 | 2,919,000 | 2,928,000 | 36,000 | 9,000 | 36,000 | 976,000 | 1,453,000 | 10,419,000 | 6,537,000 | 10,896,000 | 16,344,000 | 21,991,000 | 27,674,000 | 37,787,000 | 36,438,000 | 47,916,000 | 49,666,000 | 51,416,000 | 47,583,000 | 57,381,000 | 833,000 | 8,219,000 | 2,623,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| short-term investments | 47,641,000 | 36,268,000 | 13,975,000 | 21,802,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| other non-current assets | 1,399,000 | 1,246,000 | 2,736,000 | 3,102,000 | 3,918,000 | 4,446,000 | 4,594,000 | 4,709,000 | 5,437,000 | 5,495,000 | 5,270,000 | 5,391,000 | 5,708,000 | 5,448,000 | 5,543,000 | 4,731,000 | 4,629,000 | 4,401,000 | 4,321,000 | 3,986,000 | 3,732,000 | 3,774,000 | 4,024,000 | 1,371,000 | 10,057,000 | 6,863,000 | 4,343,000 | 3,721,000 | 3,611,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| current portion of long-term debt | 276,000 | 601,000 | 1,025,000 | 1,486,000 | 2,691,000 | 3,271,000 | 3,877,000 | 4,489,000 | 4,863,000 | 5,246,000 | 5,547,000 | 5,814,000 | 6,052,000 | 6,234,000 | 6,458,000 | 6,674,000 | 4,752,000 | 3,946,000 | 4,034,000 | 3,960,000 | 3,422,000 | 3,344,000 | 37,000 | 75,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| leaseback financing obligation | 108,745,000 | 108,745,000 | 108,745,000 | 108,745,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| long–term investments | 21,255,000 | 21,593,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| long-term deferred revenues | 12,405,000 | 13,135,000 | 13,865,000 | 14,595,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| prepaid royalty | 94,000,000 | 94,000,000 | 94,000,000 | 94,000,000 | 94,000,000 | 94,000,000 | 94,000,000 | 94,000,000 | 94,000,000 | 94,000,000 | 94,000,000 | 94,000,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| long-term debt | 47,438,000 | 47,933,000 | 48,526,000 | 49,152,000 | 50,129,000 | 51,205,000 | 52,403,000 | 53,590,000 | 54,941,000 | 56,400,000 | 57,950,000 | 59,452,000 | 43,096,000 | 32,473,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| reclassification of share based compensation liability | 933,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| deferred compensation | -95,000 | -198,000 | -312,000 | -424,000 | -550,000 | -667,000 | -784,000 | -891,000 | -1,008,000 | -1,124,000 | -1,361,000 | -1,481,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| notes receivable from stockholders | -69,000 | -69,000 | -69,000 | -69,000 | -139,000 | -139,000 | -139,000 | -139,000 | -208,000 | -208,000 | -208,000 | -277,000 | -381,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| deposits and restricted cash | 5,250,000 | 18,244,000 | 17,694,000 | 17,551,000 | 25,539,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| prepaid royalties | 95,000,000 | 95,000,000 | 95,000,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| long-term debt, net of current portion | 63,946,000 | 54,934,000 | 19,105,000 | 19,123,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| restricted cash and other non-current assets | 29,739,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| current portion of capital lease obligations | 2,939,000 | 2,179,000 | 1,881,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| capital lease obligations, net of current portion | 5,363,000 | 5,277,000 | 4,473,000 | 3,635,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| licensed technology and patent applications costs | 98,000 | 121,000 |
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