7Baggers

Windtree Therapeutics
(NASDAQ:WINT) 

WINT stock logo

Windtree Therapeutics, Inc. is advancing multiple late-stage interventions for acute cardiovascular and pulmonary disorders to treat patients in moments of crisis. Using new clinical approaches, Windtree is developing a multi-asset franchise anchored around compounds with an ability to activate SERC...

Founded: 1992
Sector: Manufacturing
Industry: Biological Product (except Diagnostic) Manufacturing
Cardiovascular
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At a glance:
Bull Thesis:
Bear Thesis:
Main Competitors:
Moat:
Income Statements:
Quarterly
Annual
    Unit: USD2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2012-12-31 2011-12-31 
                                 
      expenses:
    		                             
      research and development
    		2,253,000 3,053,000 2,110,000 1,763,000 1,415,000 1,216,000 1,543,000 2,995,000 5,345,000 4,476,000 4,680,000 4,221,000 4,410,000 3,535,000 3,882,000 4,495,000 3,461,000 2,140,000 3,792,000 3,413,000 3,342,000 2,368,000 2,197,000 2,879,000 3,118,000 2,418,000 3,062,000   
      general and administrative
    		2,152,000 1,906,000 2,580,000 2,420,000 2,292,000 2,242,000 2,653,000 2,907,000 2,988,000 2,966,000 3,467,000 3,371,000 4,669,000 3,426,000 4,823,000 3,453,000 3,242,000 2,414,000 3,395,000 3,240,000 3,355,000 2,787,000 1,500,000 1,208,000 1,926,000 1,182,000 1,749,000   
      loss on impairment of goodwill
    		   2,574,000 484,000 534,000 454,000 11,636,000                      
      total operating expenses
    		4,405,000 4,959,000 4,690,000 6,757,000 4,191,000 10,812,000 4,650,000 17,538,000 8,333,000 14,692,000 8,147,000 45,362,000 9,079,000 6,961,000 8,705,000 7,948,000 6,703,000 5,134,250 7,187,000 6,653,000 6,697,000         
      operating income
    		-4,405,000 -4,959,000 -4,690,000 -6,757,000 -4,191,000 -10,812,000 -4,650,000 -17,538,000 -8,333,000 -14,692,000 -8,147,000 -45,362,000 -9,079,000 -6,961,000 -8,705,000 -7,948,000 -6,703,000 -4,554,000 -7,187,000 -6,495,000 -6,657,000 -4,851,000 -3,468,000 -3,036,000 -4,840,000 -3,498,000 -4,794,000   
      yoy
    		5.11% -54.13% 0.86% -61.47% -49.71% -26.41% -42.92% -61.34% -8.22% 111.06% -6.41% 470.73% 35.45% 52.85% 21.12% 22.37% 0.69% -6.12% 107.24% 113.93% 37.54% 38.68% -27.66%       
      qoq
    		-11.17% 5.74% -30.59% 61.23% -61.24% 132.52% -73.49% 110.46% -43.28% 80.34% -82.04% 399.64% 30.43% -20.03% 9.52% 18.57% 47.19% -36.64% 10.65% -2.43% 37.23% 39.88% 14.23% -37.27% 38.36% -27.03%    
      operating margin %
    		-Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -4110.76% -16642.50% -1595.72% -1514.41% -288.87% -2372.55% -Infinity% -Infinity%   
      other income:
    		                             
      gain on debt extinguishment
    		14,520,000                             
      interest income
    		30,000 61,000 112,000 108,000 44,000 52,000 39,000 17,000 1,000 1,000 1,000 39,000 50,000 7,000 21,000 5,000 89,000 29,000 25,000 39,000 60,000 6,000 1,000 4,000 4,000 3,000 3,000   
      interest expense
    		-13,000 -12,000 -13,000 -13,000 -12,000 -13,000 -14,000 -13,000 -13,000 -13,000 -14,000 -46,000 -41,000 -4,000 -46,000 -31,000 -44,000 -137,000 -105,000 -117,000 -136,000 -767,000 -460,000 -92,000 -90,000 15,000 -652,000   
      other income
    		201,000 -244,000 166,000 61,000 48,000 -286,000 569,000 201,000 218,000    109,000 -437,500 -290,000 -1,584,000 124,000 -3,055,000 141,000 136,000 196,000 -85,000  72,000 414,000     
      total other income
    		14,738,000 -195,000 265,000 156,000 80,000 -247,000 594,000 205,000 206,000    118,000 -439,000 -315,000 -1,610,000              
      income before income taxes
    		10,333,000     -11,059,000 -4,056,000 -17,333,000  -14,728,000 -8,213,000 -45,721,000                  
      income tax expense
    		-114,000                             
      net income
    		10,219,000 -5,154,000 -4,425,000 -6,601,000 -4,111,000 -9,692,000 -4,056,000 -17,333,000 -8,127,000 -13,073,000 -8,213,000 -37,389,000 -8,961,000 -7,454,000 -9,020,000 -9,558,000 -6,534,000 -7,375,000 -7,126,000 -6,437,000 -6,537,000 -9,042,000 -3,927,000 -3,052,000 -4,512,000 2,473,000 -5,443,000   
      yoy
    		-348.58% -46.82% 9.10% -61.92% -49.42% -25.86% -50.61% -53.64% -9.31% 75.38% -8.95% 291.18% 37.14% 1.07% 26.58% 48.49% -0.05% -18.44% 81.46% 110.91% 44.88% -465.63% -27.85%       
      qoq
    		-298.27% 16.47% -32.96% 60.57% -57.58% 138.95% -76.60% 113.28% -37.83% 59.17% -78.03% 317.24% 20.22% -17.36% -5.63% 46.28% -11.40% 3.49% 10.70% -1.53% -27.70% 130.25% 28.67% -32.36% -282.45% -145.43%    
      net income margin %
    		Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -4074.05% -16342.50% -2974.34% -1714.85% -290.39% -2211.76% Infinity% -Infinity%   
      net income per common share
    		                             
      basic and diluted
    		21,980 -740 -860 -1,640 -4,760 -61,230 -130 -590 -290 -420 -310 -1,420 -510 -430 -540 -630 -480 -220 -220 -200 -200 -4,530 -1,040 -810 -1,400 -21,380 -690   
      weighted-average number of common shares outstanding
    		                             
      basic and diluted
    		465,000 3,876,000 5,148,000 4,030,000 863,000 630,000 31,135,000 29,200,000 28,295,000 24,760,000 26,704,000 26,350,000 17,695,000 15,654,000 16,579,000 15,091,000 13,697,000 32,784,000 32,189,000 32,189,000 32,142,000 4,493,000 3,769,000 3,751,000 3,227,000 1,028,000 10,647,000   
      loss on impairment of intangible assets
    		         7,250,000  37,770,000                  
      deferred income tax benefit
    		         1,655,000  8,332,000                  
      other (expense)
    		         -74,000 -53,000 -352,000                  
      total other (expense)
    		         -76,750 -66,000 -359,000                  
      revenues:
    		                             
      license revenue with affiliate
    		                   158,000 40,000 304,000 159,000 356,000 204,000     
      total revenues
    		                   158,000 40,000 304,000 229,000 1,051,000 204,000     
      yoy
    		                   -84.97% -80.39%         
      qoq
    		                   295.00% -86.84% 32.75% -78.21% 415.20%      
      other income /
    		                             
      other income / (expense)
    		                169,000 59,750 61,000 58,000 120,000 -4,191,000 -459,000 -16,000 328,000 5,971,000 -649,000   
      grant revenue
    		                      70,000 695,000   17,000   
      total operating expense
    		                     5,155,000 3,697,000 4,087,000 5,044,000 3,600,000 4,811,000   
      deemed dividend on series a preferred stock
    		                         -319,000 -1,915,000   
      net income attributable to common shareholders
    		                     -23,265,000 -3,927,000 -3,052,000 -4,512,000 2,154,000 -7,358,000   
      change in fair value of common stock warrant liability
    		                             
    Balance Sheets:
    Quarterly
    Annual
      Unit: USD2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2012-12-31 2011-12-31 
                                   
        assets
      		                             
        current assets:
      		                             
        cash and cash equivalents
      		2,547,000 4,319,000 7,365,000 11,467,000 4,235,000 6,172,000 8,436,000 11,378,000 15,541,000 22,348,000 24,541,000 29,965,000 38,490,000 16,930,000 22,356,000 31,515,000 16,799,000 22,578,000 4,437,000 6,124,000 2,053,000 11,187,000 640,000 638,000 1,854,000 1,815,000 1,752,000 26,892,000 10,189,000 
        prepaid expenses and other current assets
      		792,000 1,060,000 1,543,000 1,852,000 987,000 1,205,000 1,596,000 1,784,000 906,000 1,143,000 1,826,000 2,329,000 851,000 1,188,000 1,692,000 2,121,000 1,299,000 1,283,000 826,000 1,219,000 502,000 507,000 399,000 397,000 129,000 422,000 248,000 719,000 442,000 
        total current assets
      		3,339,000 5,379,000 8,908,000 13,319,000 5,222,000 7,377,000 10,032,000 13,162,000 16,447,000 23,491,000 26,367,000 32,294,000 39,341,000 18,118,000 24,048,000 33,636,000 18,098,000 23,861,000 5,263,000 9,883,000 16,069,000 25,653,000 1,039,000 1,035,000 1,983,000 2,237,000 3,094,000 27,806,000 10,631,000 
        property and equipment
      		162,000 183,000 205,000 216,000 239,000 262,000 286,000 307,000 548,000 1,011,000 890,000 834,000 879,000 924,000 702,000 727,000 756,000 798,000 877,000 893,000 826,000 802,000 764,000 804,000 844,000 885,000 930,000 1,737,000 2,293,000 
        restricted cash
      		9,000 150,000 150,000 150,000 163,000 154,000 154,000 154,000 154,000 154,000 154,000 154,000 154,000 154,000 154,000 154,000 154,000 154,000 154,000 153,000 171,000 171,000 140,000 140,000 140,000 225,000 225,000 400,000 400,000 
        operating lease right-of-use assets
      		1,343,000 1,444,000 1,544,000 1,640,000 1,737,000 1,853,000 1,964,000 2,074,000 2,207,000 2,381,000 2,412,000 2,581,000 2,747,000 917,000 855,000 1,034,000 1,213,000 1,390,000 1,566,000 1,544,000 1,788,000         
        intangible assets
      		25,250,000 25,250,000 25,250,000 25,250,000 25,250,000 25,250,000 32,070,000 32,070,000 32,070,000 32,070,000 39,320,000 39,320,000 77,090,000 77,090,000 77,090,000 77,090,000 77,090,000 77,090,000 77,090,000 77,090,000 77,090,000 77,090,000        
        total assets
      		30,103,000 32,406,000 36,057,000 40,575,000 35,185,000 37,954,000 48,098,000 51,813,000 67,108,000 74,789,000 84,825,000 90,865,000 135,893,000 112,885,000 118,531,000 128,323,000 112,993,000 118,975,000 100,632,000 105,245,000 111,626,000 119,398,000 1,943,000 1,979,000 2,967,000 3,347,000 4,657,000 29,943,000 13,324,000 
        liabilities & stockholders’ equity
      		                             
        current liabilities:
      		                             
        accounts payable
      		1,689,000 809,000 944,000 964,000 753,000 249,000 410,000 1,072,000 724,000 693,000 582,000 288,000 939,000 1,161,000 726,000 1,223,000 1,401,000 1,708,000 607,000 724,000 1,417,000 3,420,000 4,519,000 4,258,000 4,683,000 3,048,000 3,770,000 1,166,000 1,111,000 
        accrued expenses
      		2,125,000 1,618,000 1,859,000 1,731,000 1,621,000 1,552,000 2,496,000 2,823,000 3,554,000 3,408,000 3,549,000 3,111,000 3,744,000 3,813,000 4,279,000 3,676,000 2,971,000 3,226,000 5,235,000 4,627,000 5,247,000 6,465,000 4,069,000 3,974,000 3,997,000 4,204,000 5,365,000 4,159,000 2,972,000 
        operating lease liabilities - current portion
      		446,000 436,000 439,000 399,000 389,000 404,000 416,000 432,000 472,000 528,000 278,000 336,000 392,000 805,000 605,000 651,000 700,000 750,000 781,000 656,000 730,000         
        loans payable
      		  467,000 700,000               7,782,000 8,047,000          
        other current liabilities
      		725,000 900,000                            
        total current liabilities
      		4,985,000 3,996,000 3,709,000 3,794,000 2,763,000 2,457,000 3,951,000 5,334,000 4,750,000 4,923,000 5,143,000 4,910,000 7,484,000 6,131,000 6,314,000 12,232,000 6,939,000 7,817,000 16,278,000 15,535,000 16,960,000 20,633,000 18,110,000 15,181,000 15,737,000 11,760,000 29,488,000 11,699,000 11,147,000 
        operating lease liabilities - non-current portion
      		1,038,000 1,161,000 1,251,000 1,397,000 1,512,000 1,624,000 1,732,000 1,839,000 1,944,000 2,071,000 2,196,000 2,318,000 2,438,000 201,000 358,000 506,000 654,000 794,000 953,000 1,070,000 1,251,000         
        restructured debt liability - contingent milestone payments
      		 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000    
        other liabilities
      		3,800,000 3,800,000 3,800,000 3,800,000 3,800,000 3,800,000 3,800,000 3,800,000 3,800,000 3,800,000 3,600,000 3,200,000 2,800,000 2,800,000 2,400,000 1,000,000   106,000 94,000 63,000 175,000 166,000 182,000 93,000 100,000 117,000 443,000 689,000 
        deferred tax liabilities
      		4,859,000 5,058,000 4,813,000 4,980,000 5,081,000 5,061,000 6,195,000 6,643,000 6,885,000 7,114,000 8,707,000 8,674,000 16,683,000 16,778,000 16,370,000 16,129,000 15,759,000 15,821,000 15,224,000 15,276,000 15,356,000 15,476,000        
        total liabilities
      		14,682,000 29,015,000 28,573,000 28,971,000 28,156,000 27,942,000 30,678,000 32,616,000 32,379,000 32,908,000 34,646,000 34,102,000 44,405,000 43,333,000 42,806,000 44,867,000 42,903,000 44,040,000 47,561,000 46,975,000 48,630,000 51,284,000 33,276,000 30,363,000 31,033,000 27,267,000 42,105,000 12,290,000 12,060,000 
        stockholders’ equity:
      		                             
        preferred stock, 0.001 par value...
      		                             
        common stock, 0.001 par value...
      		1,000 6,000 5,000 5,000 1,000  33,000 29,000 28,000 28,000 27,000 27,000 26,000 17,000 17,000 17,000 14,000 41,000 32,000 32,000 32,000 32,000 4,000 4,000 3,000 3,000 16,000 44,000 25,000 
        additional paid-in capital
      		853,078,000 851,262,000 850,202,000 849,897,000 838,725,000 837,598,000 835,281,000 833,006,000 831,206,000 830,231,000 825,457,000 823,828,000 821,165,000 790,277,000 788,996,000 787,707,000 764,786,000 763,070,000 733,840,000 731,901,000 730,162,000 728,783,000 620,322,000 619,344,000 616,611,000 616,245,000 605,177,000 455,398,000 401,713,000 
        accumulated deficit
      		-834,604,000 -844,823,000 -839,669,000 -835,244,000 -828,643,000 -824,532,000 -814,840,000 -810,784,000 -793,451,000 -785,324,000 -772,251,000 -764,038,000 -726,649,000 -717,688,000 -710,234,000 -701,214,000 -691,656,000 -685,122,000 -677,747,000 -670,621,000 -664,184,000 -657,647,000 -648,605,000 -644,678,000  -637,114,000 -639,587,000 -434,735,000 -397,420,000 
        treasury stock
      		-3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 -3,054,000 
        total stockholders’ equity
      		15,421,000 3,391,000 7,484,000 11,604,000 7,029,000 10,012,000 17,420,000 19,197,000 34,729,000 41,881,000 50,179,000 56,763,000 91,488,000 69,552,000              17,653,000 1,264,000 
        total liabilities & stockholders’ equity
      		30,103,000      48,098,000 51,813,000 67,108,000 74,789,000 84,825,000 90,865,000 135,893,000 112,885,000              29,943,000 13,324,000 
        goodwill
      		    2,574,000 3,058,000 3,592,000 4,046,000 15,682,000 15,682,000 15,682,000 15,682,000 15,682,000 15,682,000 15,682,000 15,682,000 15,682,000 15,682,000 15,682,000 15,682,000 15,682,000 15,682,000        
        liabilities, mezzanine equity & stockholders’ equity
      		                             
        loans payable - current portion
      		 233,000    252,000 629,000 1,007,000  294,000 734,000 1,175,000 2,409,000 352,000 704,000 5,714,000  161,000            
        mezzanine equity:
      		                             
        series a redeemable preferred stock, 0.001 par value...
      		                             
        total liabilities, mezzanine equity & stockholders’ equity
      		 32,406,000 36,057,000 40,575,000 35,185,000 37,954,000                        
        loans payable - non-current portion
      		             2,423,000 2,364,000  4,551,000 4,608,000            
        collaboration and device development payable
      		               968,000 1,867,000 1,972,000 1,873,000 1,481,000 1,939,000 2,576,000        
        liabilities & stockholders' equity
      		                             
        stockholders' equity:
      		                             
        total stockholders' equity
      		              75,725,000 83,456,000 70,090,000 74,935,000 53,071,000 58,270,000 62,996,000 68,114,000 -31,333,000 -28,384,000 -28,066,000 -23,920,000 -37,448,000   
        total liabilities & stockholders' equity
      		              118,531,000 128,323,000 112,993,000 118,975,000 100,632,000 105,245,000 111,626,000 119,398,000 1,943,000 1,979,000 2,967,000 3,347,000 4,657,000   
        available-for-sale marketable securities
      		                   2,540,000 13,514,000 13,959,000        
        deferred revenue - current portion
      		                     198,000 503,000 731,000 884,000 884,000    
        deferred revenue
      		                    158,000      1,070,000   
        accumulated other comprehensive income
      		                   12,000 40,000         
        loan payable
      		                    7,469,000 7,974,000 4,280,000 2,500,000 2,500,000  2,600,000   
        deferred revenue - non-current portion
      		                        203,000 407,000    
        collaboration payable
      		                      3,770,000 3,718,000 3,673,000 3,624,000 4,183,000   
        convertible note payable, 1,500 net of discount of 531 at september 30, 2018
      		                      969,000       
        accumulated defi
      		                        -641,626,000     
        prepaid interest, current portion
      		                          1,094,000   
        prepaid interest, non-current portion
      		                          408,000   
        long-term debt
      		                             
        long-term debt, current portion
      		                          12,500,000   
        long-term debt, non-current portion
      		                          12,500,000   
        inventory
      		                           195,000  
        common stock warrant liability
      		                           6,305,000 6,996,000 
        equipment loans and capitalized leases, current portion
      		                           69,000 68,000 
        equipment loans and capitalized leases, non-current portion
      		                           148,000 224,000 
        other assets
      		                             
      Cashflow Statements:
      Quarterly
      Annual
        Unit: USD2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 
                                  
          cash flows from operating activities:
        		                          
          net income
        		10,219,000 -5,154,000 -4,425,000 -6,601,000 -4,111,000 -9,692,000 -4,056,000 -17,333,000 -8,127,000 -13,073,000 -8,213,000 -37,389,000 -8,961,000 -7,454,000 -9,020,000 -9,558,000 -6,534,000 -7,375,000 -7,126,000 -6,437,000 -6,537,000 -9,042,000 -3,927,000 -3,052,000 -4,512,000 2,473,000 
          adjustments to reconcile net income to net cash from operating activities:
        		                          
          depreciation and amortization
        		21,000 22,000 14,000 23,000 23,000 24,000 21,000 22,000 466,000 52,000 47,000             41,000 41,000 45,000 
          stock-based compensation
        		251,000 306,000 305,000 382,000 285,000 791,000 744,000 781,000 770,000 1,622,000 1,629,000 1,544,000 2,443,000 1,281,000 1,148,000 1,566,000 1,689,000 1,513,000 1,939,000 1,739,000 1,530,000 252,000     
          non-cash lease expense
        		101,000 100,000 96,000 97,000 116,000 111,000 110,000 133,000 174,000 172,000 169,000 166,000 170,000 -62,000 179,000 179,000 177,000          
          loss on impairment of goodwill
        		 0 0 2,574,000 484,000 534,000 454,000                    
          gain on debt extinguishment
        		-14,520,000                          
          unrealized (gain) loss on foreign exchange rate changes
        		-209,000     231,000 -456,000                    
          changes in assets and liabilities:
        		                          
          prepaid expenses and other current assets
        		270,000 480,000 311,000 -86,000 218,000 389,000 191,000 257,000 239,000 683,000 503,000 -158,000 337,000 502,000 427,000 234,000 -16,000 299,000 457,000 -73,000 5,000 279,000 -2,000 -268,000 293,000 -174,000 
          accounts payable
        		880,000 -135,000 -20,000 211,000 504,000 -161,000 -662,000 348,000 31,000 111,000 294,000 -651,000 -222,000 435,000 -497,000 -178,000 -307,000 345,000 -117,000 -693,000 -2,003,000 -474,000 261,000 -425,000 1,635,000 -722,000 
          accrued expenses
        		328,000 -251,000 135,000 114,000 68,000 -940,000 -322,000 -727,000 151,000 -143,000 439,000 -634,000 -69,000 -468,000 628,000 663,000 -238,000 -2,025,000 560,000 -608,000 -1,118,000 -208,000 80,000 118,000 -266,000 -1,168,000 
          operating lease liabilities
        		-113,000 -93,000 -106,000 -105,000 -127,000 -120,000 -123,000 -145,000 -183,000 -16,000 -180,000 -176,000 -176,000 43,000 -194,000 -197,000 -190,000 -190,000 -319,000 -251,000 -214,000      
          other current liabilities
        		-175,000                          
          net cash from operating activities
        		-2,947,000 -3,567,000 -3,854,000 -3,497,000 -2,519,000 -3,380,000 -4,099,000 -5,258,000 -6,715,000 -4,932,000 -5,281,000 -7,403,000 -6,048,000 -4,539,000 -8,256,000 -7,038,000 -5,482,000 -5,459,000 -3,824,000 -6,621,000 -8,759,000 -6,191,000 -3,278,000 -3,766,000 -2,546,000 -4,808,000 
          capital expenditures
        		0 0 0 0 0 0 0 -10,000 -3,000 -173,000 -103,000 0 0 -264,000 -15,000 0 0 -62,000 97,000 -152,000 -74,000 0 0 0 0 0 
          free cash flows
        		-2,947,000 -3,567,000 -3,854,000 -3,497,000 -2,519,000 -3,380,000 -4,099,000 -5,268,000 -6,718,000 -5,105,000 -5,384,000 -7,403,000 -6,048,000 -4,803,000 -8,271,000 -7,038,000 -5,482,000 -5,521,000 -3,727,000 -6,773,000 -8,833,000 -6,191,000 -3,278,000 -3,766,000 -2,546,000 -4,808,000 
          cash flows from financing activities:
        		                          
          proceeds from atm program, net of issuance costs
        		1,367,000     1,493,000 1,535,000 1,020,000 205,000                  
          principal payments on loans payable
        		-233,000 -234,000 -233,000 -78,000 -252,000 -377,000 -378,000 -125,000 -294,000 -441,000 -440,000 -2,639,000 -352,000              
          payments on debt extinguishment
        		-100,000                          
          proceeds from exercise of common stock warrants, net of expenses
        		 0 0 0 843,000                      
          net cash from financing activities
        		1,034,000 521,000 -233,000 10,716,000 591,000 1,116,000 1,157,000 895,000 -89,000 2,912,000 -40,000 -1,119,000 27,608,000 48,000 -1,137,000 21,246,000 -199,000     30,417,000 3,279,000 2,542,000 2,500,000 4,871,000 
          net decrease in cash, cash equivalents, and restricted cash
        		-1,913,000    -1,928,000                      
          cash, cash equivalents, and restricted cash - beginning of period
        		4,469,000  0 0 6,326,000  0 0 22,502,000  0 0 17,084,000              
          cash, cash equivalents, and restricted cash - end of period
        		2,556,000  -4,102,000 7,219,000 4,398,000  -2,942,000 -4,163,000 15,695,000  -5,424,000 -8,525,000 38,644,000              
          supplementary disclosure of non-cash activity:
        		                          
          fair value of common stock consideration related to debt extinguishment
        		280,000                          
          fair value of january 2023 warrant modifications related to the january 2023 warrant exercise inducement
        		 0 0 0 1,238,000                      
          fair value of february 2023 warrant modifications related to the february 2023 warrant exercise inducement
        		 0 0 0 274,000                      
          see notes to condensed consolidated financial statements
        		                          
          loss on impairment of intangible assets
        		         7,250,000 0                
          loss on sale and disposal of property and equipment
        		 0    0 0                    
          deferred income tax benefit
        		         -1,655,000 0                
          unrealized gain on foreign exchange rate changes
        		 258,000 -176,000 -106,000 21,000    -236,000    -109,000              
          cash flows from investing activities:
        		                          
          proceeds from sale of property and equipment
        		     0 0               0 0    
          purchase of property and equipment
        		 0    0 0 -10,000 -3,000 -173,000 -103,000   -264,000 -15,000   -62,000 97,000 -152,000 -74,000     0 
          net cash from investing activities
        		 0    0 0 200,000 -3,000 -173,000 -103,000   -264,000 -15,000   -62,000 2,597,000 10,837,000 425,000 -13,736,000 0   0 
          proceeds from issuance of common stock and warrants, net of issuance costs
        		 0 0       0 0 0 27,390,000 0 0            
          cash, cash equivalents, and restricted cash - beginning of year
        		                          
          cash, cash equivalents, and restricted cash - end of year
        		                          
          prepayment of insurance through third-party financing
        		 0 0   0 0   0 0                
          net increase in cash, cash equivalents, and restricted cash
        		  -4,102,000   -2,264,000 -2,942,000 -4,163,000 -6,807,000 -2,193,000 -5,424,000 -8,525,000 21,560,000              
          non-cash expense related to equity consideration for a service agreement
        		         0 0 0 494,000              
          proceeds from research and development funding arrangement
        		         200,000 400,000   400,000 1,400,000            
          operating lease liabilities arising from obtaining right-of-use assets
        		         141,000 0 0 2,000,000              
          non-cash expense related to warrant modifications
        		             0 0            
          unrealized loss on foreign exchange rate changes
        		         65,000 31,000                
          collaboration and device development payable
        		             0 -968,000 -899,000 -108,000 63,000 357,000 -495,000 -692,000      
          proceeds from atm program, net of expenses
        		         3,153,000 0               0 
          proceeds from exercise of common stock warrants
        		             0             
          proceeds from paycheck protection program loan
        		                          
          principal payments on paycheck protection program loan
        		                          
          effect of exchange rate changes on cash and cash equivalents
        		              249,000 520,000 -98,000  -113,000 -136,000 -202,000      
          depreciation
        		            45,000 42,000 41,000 40,000 42,000 17,000 39,000 89,000 50,000 38,000     
          amortization of debt discount
        		             0 0 0 3,000 36,000 35,000 37,000 55,000 560,000     
          changes in:
        		                          
          proceeds from the atm program, net of expenses
        		            570,000              
          net income on extinguishment of debt
        		                          
          recognition of deferred revenue
        		                 0 0 -158,000 -40,000   -356,000 -204,000  
          realized gain on investments
        		                  -14,000 -50,000 -11,000      
          other liabilities
        		                 -112,000 60,000 35,000 24,000      
          proceeds from sale of marketable securities
        		                  2,500,000 10,989,000 499,000      
          proceeds from payroll protection program loan
        		             0 0            
          principal payments on payroll protection program loan
        		                          
          proceeds from private placement issuance of securities, net of expenses
        		                     30,352,000 -1,000   6,071,000 
          proceeds from loan payable, net of expenses
        		                     1,880,000 1,780,000 0 2,500,000  
          payments for taxes related to net share settlements of restricted stock units
        		                          
          principle payments on payroll protection program loan
        		              0            
          principle payments on loans payable
        		              -2,678,000 0 -199,000          
          payment for taxes related to net share settlements of restricted stock units
        		                  0 0 -151,000      
          prepayment of insurance through 3rd party financing
        		              0            
          net increase in cash, cash equivalents and restricted cash
        		                          
          cash, cash equivalents and restricted cash - beginning of period
        		               0 22,732,000  0        
          cash, cash equivalents and restricted cash - end of period
        		               14,716,000 16,953,000  -1,686,000        
          net decrease in cash and cash equivalents
        		                -5,779,000  -1,686,000 4,053,000 -9,134,000      
          net realized gain on sale of marketable securities
        		                          
          gain on sale of equipment
        		                          
          sale of marketable securities
        		                          
          purchase of marketable securities
        		                          
          cash acquired in cvie acquisition
        		                          
          repayment of loan payable
        		                          
          proceeds from convertible note payable
        		                     0     
          repayment of convertible note payable
        		                          
          effect of exchange rates on cash and cash equivalents
        		                          
          net increase/(decrease) in cash and cash equivalents
        		                      2,000 -1,216,000 -46,000 63,000 
          cash, cash equivalents and restricted cash - beginning of year
        		                    11,358,000 0 0 0 2,040,000 0 
          cash, cash equivalents and restricted cash - end of year
        		                    2,224,000 10,578,000 2,000 -1,216,000 1,994,000 63,000 
          amortization of operating lease right-of-use assets
        		                  305,000 244,000 192,000      
          gain on sale of property and equipment
        		                      0    
          net cash (used in) / provided by financing activities
        		                  -346,000 -27,000 -598,000      
          prepayment of director and officer insurance through 3rd party financing
        		                  0        
          principle payments on loan payable
        		                   -27,000 -447,000      
          amortization of prepaid interest
        		                         94,000 
          gain on debt restructuring
        		                          
          deferred revenue - current
        		                          
          deferred revenue - non-current
        		                          
          principal payments on debt restructuring
        		                          
          effect of exchange rates on cash
        		                          
          net increase/(decrease) in cash, cash equivalents and restricted cash
        		                          
          supplementary disclosure of cash flows information:
        		                          
          interest paid
        		                         574,000 
          collaboration payable
        		                      52,000 45,000 49,000 -559,000 
          deferred revenue
        		                          
          stock-based compensation and 401(k) plan employer match
        		                       140,000 418,000 816,000 
          fair value adjustment of common stock warrants
        		                          
          loss on sale or disposal of equipment
        		                          
          gain/(loss) on sale or disposal of equipment
        		                          
          proceeds from loan payable
        		                          
          stock–based compensation and 401(k) plan employer match
        		                          
          loss / (gain) on disposal of equipment
        		                          
          inventory
        		                          
          other assets
        		                          
          other liabilities and accrued interest on loan payable
        		                          
          proceeds from issuance of securities, net of expenses
        		                          
          proceeds from exercise of stock options
        		                          
          principal payments of loan payable
        		                          
          principal payments under equipment loan and capital lease obligations
        		                          
          net increase in cash and cash equivalents
        		                          
          cash and cash equivalents as of beginning of year
        		                          
          cash and cash equivalents as of end of year
        		                          
          equipment acquired through capitalized lease
        		                          
          cash flow from operating activities:
        		                          
          stock–based compensation and 401(k) match
        		                          
          loss / (gain) on sale of equipment
        		                          
          cash flow from investing activities:
        		                          
          cash flow from financing activities:
        		                          
          cash and cash equivalents – beginning of year
        		                          
          cash and cash equivalents – end of year
        		                          
          non-cash transactions: