7Baggers

UroGen Pharma Ltd
(NASDAQ:URGN) 

URGN stock logo

UroGen Pharma Ltd., a biopharmaceutical company, engages in the development and commercialization novel solutions for specialty cancers and urologic diseases. It offers RTGel, a polymeric biocompatible and reverse thermal gelation hydrogel to improve therapeutic profiles of existing drugs; and Jelmy...

Founded: 2004
Full Time Employees: 187
Sector: Healthcare
Industry: Biotechnology

Share this website to your friends
• Market Cap:
• Exchange:
• Shs Outstanding:
• Employees:
• Beta:
• Return on Equity (ROE) ttm:
• Return on Assets (ROA) ttm:
• EPS ttm:
• Book value per Share:
• Cash per Share:
• Current ast per Share:
• P/E ttm:
• P/E forward:
• P/E ttm high:
• P/E ttm low:
• P/S ttm:
• P/B ttm:
• P/FCF ttm:
• PEG ratio:
• Cash Ratio ttm:
• Quick Ratio ttm:
• Current Ratio ttm:
• Gross Mgn ttm:
• EBITDA Mgn ttm:
• Operating Mgn ttm:
• Net Income Mgn ttm:
• Trailing Div yield:
• Forward Div yield:
• Payout Ratio ttm:
• Ex-Dividend date:
• Target Price High:
• Target Price Low:
• Target Price Mean:
• Number of Analysts:
• Debt Ratio ttm:
• Debt to Equity ttm:
• Total Net Debt:
At a glance:
Bull Thesis:
Bear Thesis:
Main Competitors:
Moat:
Income Statements:
Quarterly
Annual
    Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-08-14 2018-05-15 2018-03-15 2017-12-31 2017-11-14 2017-08-14 
                                         
      revenue
    50,959,000 37,837,000 27,482,000 24,215,000 20,254,000 24,565,000 25,204,000 21,848,000 18,781,000 23,530,000 20,852,000 21,139,000 17,192,000 18,092,000 16,097,000 16,604,000 13,564,000 16,174,000 11,351,000 13,032,000                  
      yoy
    151.60% 54.03% 9.04% 10.83% 7.84% 4.40% 20.87% 3.35% 9.24% 30.06% 29.54% 27.31% 26.75% 11.86% 41.81% 27.41%                      
      qoq
    34.68% 37.68% 13.49% 19.56% -17.55% -2.54% 15.36% 16.33% -20.18% 12.84% -1.36% 22.96% -4.97% 12.39% -3.05% 22.41% -16.14% 42.49% -12.90%                   
      cost of revenue
    4,139,000 3,289,000 3,278,000 3,550,000 2,330,000 2,471,000 2,453,000 2,229,000 1,728,000 2,286,000 2,367,000 2,443,000 2,265,000 2,263,000 2,020,000 1,846,000 1,525,000 1,589,000 1,244,000 1,427,000                  
      gross profit
    46,820,000 34,548,000 24,204,000 20,665,000 17,924,000 22,094,000 22,751,000 19,619,000 17,053,000 21,244,000 18,485,000 18,696,000 14,927,000 15,829,000 14,077,000 14,758,000 12,039,000 14,585,000 10,107,000 11,605,000 6,588,000 7,314,000 3,152,000 324,000    18,000   -772,000 46,000 51,000 40,000 40,000 7,517,000  
      yoy
    161.21% 56.37% 6.39% 5.33% 5.11% 4.00% 23.08% 4.94% 14.24% 34.21% 31.31% 26.68% 23.99% 8.53% 39.28% 27.17% 82.74% 99.41% 220.65% 3481.79% NaN%  NaN% 1700.00% NaN%  NaN% -60.87% NaN%  -2030.00% -99.39% NaN%     
      qoq
    35.52% 42.74% 17.13% 15.29% -18.87% -2.89% 15.96% 15.05% -19.73% 14.93% -1.13% 25.25% -5.70% 12.45% -4.61% 22.58% -17.46% 44.31% -12.91% 76.15% -9.93% 132.04% 872.84% NaN%   NaN% NaN%   -1778.26% -9.80% 27.50% 0.00% -99.47% NaN%  
      gross margin %
    91.88% 91.31% 88.07% 85.34% 88.50% 89.94% 90.27% 89.80% 90.80% 90.28% 88.65% 88.44% 86.83% 87.49% 87.45% 88.88% 88.76% 90.18% 89.04% 89.05% Infinity% Infinity% Infinity% Infinity% NaN% NaN% NaN% Infinity% NaN% NaN% -Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% NaN% 
      operating expenses:
                                         
      research and development expenses
    15,597,000 14,314,000 14,008,000 18,914,000 19,871,000 14,894,000 11,355,000 15,402,000 15,494,000 11,302,000 10,230,000 11,584,000 12,498,000 14,477,000 13,093,000 12,640,000     10,513,000 12,405,000 10,211,000 8,106,000 16,588,000 20,094,000 9,481,000 9,996,000 9,726,000 11,465,000 9,574,000 8,273,000 7,622,000 6,761,000 6,761,000 5,621,000 3,651,000 
      selling, general and administrative expenses
    51,486,000 39,349,000 37,582,000 43,199,000 34,967,000 34,858,000 28,941,000 30,056,000 27,299,000 24,551,000 21,755,000 22,494,000 24,474,000 21,634,000 19,071,000 20,833,000     22,189,000 22,163,000 22,065,000 24,018,000 21,973,000             
      operating income
    -20,263,000 -19,115,000 -27,386,000 -41,448,000 -36,914,000 -27,658,000 -17,545,000 -25,839,000 -25,740,000 -14,609,000 -13,500,000 -15,382,000 -22,045,000 -20,282,000 -18,087,000 -18,715,000 -21,957,000 -19,915,000 -23,440,000 -22,823,000 -26,114,000 -27,254,000 -29,124,000 -31,800,000 -38,561,000 -39,839,000 -23,453,000 -23,753,000 -22,433,000 -130,343,000 21,089,000 18,434,000 13,640,000 -10,158,000 -29,742,000 303,000 5,951,000 
      yoy
    -45.11% -30.89% 56.09% 60.41% 43.41% 89.32% 29.96% 67.98% 16.76% -27.97% -25.36% -17.81% 0.40% 1.84% -22.84% -18.00% -15.92% -26.93% -19.52% -28.23% -32.28% -31.59% 24.18% 33.88% 71.89% -69.44% -211.21% -228.85% -264.46% 1183.16% -170.91% 5983.83% 129.21%     
      qoq
    6.01% -30.20% -33.93% 12.28% 33.47% 57.64% -32.10% 0.38% 76.19% 8.21% -12.24% -30.22% 8.69% 12.14% -3.36% -14.77% 10.25% -15.04% 2.70% -12.60% -4.18% -6.42% -8.42% -17.53% -3.21% 69.87% -1.26% 5.88% -82.79% -718.06% 14.40% 35.15% -234.28% -65.85% -9915.84% -94.91%  
      operating margin %
    -39.76% -50.52% -99.65% -171.17% -182.26% -112.59% -69.61% -118.27% -137.05% -62.09% -64.74% -72.77% -128.23% -112.10% -112.36% -112.71% -161.88% -123.13% -206.50% -175.13% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% Infinity% Infinity% Infinity% -Infinity% -Infinity% Infinity% Infinity% 
      financing on prepaid forward obligation
    -4,506,000 -4,655,000 -4,621,000 -4,644,000 -4,583,000 -6,063,000 -5,915,000 -5,773,000 -5,660,000 -5,505,000 -5,479,000 -5,344,000 -5,224,000 -5,081,000 -4,819,000 -5,833,000 -5,826,000 -7,343,000 -6,828,000 -3,120,000                  
      interest expense on long-term debt
    -4,185,000 -3,772,000 -3,373,000 -4,132,000 -4,068,000 -3,892,000 -2,721,000 -3,461,000 -2,447,000 -3,586,000 -3,815,000 -3,761,000 -3,553,000 -3,223,000 -2,694,000 -2,239,000 -282,000                     
      interest and other income
    608,000 903,000 979,000 1,299,000 2,114,000 2,750,000 2,599,000 1,708,000 1,615,000 1,538,000 906,000 405,000 630,000 406,000 478,000 128,000  -57,000 57,000 33,000 179,000 102,000 308,000 451,000 768,000 866,500 1,201,000      -358,000     
      income before income taxes
    -28,346,000 -26,639,000 -34,401,000 -48,925,000 -43,451,000 -34,863,000 -23,582,000 -33,365,000 -32,232,000 -22,162,000 -21,888,000 -24,082,000 -30,192,000 -28,180,000 -25,122,000 -26,659,000 -28,067,000 -27,315,000 -30,211,000 -25,910,000              -10,067,000    
      income tax benefit
    4,772,000 -88,250 1,054,000                                   
      net income
    -23,574,000 -26,364,000 -33,347,000 -49,940,000 -43,843,000 -37,512,000 -23,673,000 -33,403,000 -32,286,000 -26,016,000 -21,879,000 -24,136,000 -30,213,000 -28,869,000 -25,831,000 -26,691,000 -28,392,000 -28,452,000 -30,211,000 -26,222,000 -25,935,000 -30,526,000 -28,816,000 -31,349,000 -37,793,000 -38,973,000 -22,252,000 -22,477,000 -21,444,000 -127,597,000 20,533,000 18,026,000 13,382,000 -10,067,000 -29,914,000 298,000 6,199,000 
      yoy
    -46.23% -29.72% 40.87% 49.51% 35.80% 44.19% 8.20% 38.39% 6.86% -9.88% -15.30% -9.57% 6.41% 1.47% -14.50% 1.79% 9.47% -6.79% 4.84% -16.35% -31.38% -21.67% 29.50% 39.47% 76.24% -69.46% -208.37% -224.69% -260.25% 1167.48% -168.64% 5948.99% 115.87%     
      qoq
    -10.58% -20.94% -33.23% 13.91% 16.88% 58.46% -29.13% 3.46% 24.10% 18.91% -9.35% -20.11% 4.66% 11.76% -3.22% -5.99% -0.21% -5.82% 15.21% 1.11% -15.04% 5.93% -8.08% -17.05% -3.03% 75.14% -1.00% 4.82% -83.19% -721.42% 13.91% 34.70% -232.93% -66.35% -10138.26% -95.19%  
      net income margin %
    -46.26% -69.68% -121.34% -206.24% -216.47% -152.71% -93.93% -152.89% -171.91% -110.57% -104.93% -114.18% -175.74% -159.57% -160.47% -160.75% -209.32% -175.91% -266.15% -201.21% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% Infinity% Infinity% Infinity% -Infinity% -Infinity% Infinity% Infinity% 
      statements of comprehensive loss
                                         
      other comprehensive loss
                                         
      unrealized loss on investments
    -11,000    -42,000                                 
      comprehensive loss
    -23,585,000 -26,368,000 -33,330,000 -49,948,000 -43,885,000 -37,692,000 -23,406,000 -33,397,000 -32,335,000 -25,870,000 -21,859,000 -24,245,000 -30,151,000 -28,821,000 -25,930,000 -26,678,000 -28,436,000 -28,481,000 -30,252,000 -26,320,000 -26,063,000 -30,747,000 -29,084,000 -30,900,000 -37,758,000 -39,000,000 -22,230,000 -22,196,000          
      net loss per ordinary share - basic and diluted
    -470 -530 -690 -1,050 -920 -600 -550 -910 -970 -660 -680 -1,030 -1,300 -1,250 -1,130 -1,180                      
      weighted-average number of shares outstanding used in computation of basic and diluted loss per ordinary share
    50,182,758,000 48,116,098,000 48,057,386,000 47,739,816,000 47,422,119,000 42,876,737,000 43,100,237,000 36,821,915,000 33,379,786,000 28,834,303,000 32,298,182,000 23,462,016,000 23,279,951,000 22,806,812,000 22,798,263,000 22,703,572,000 22,631,509,000 22,347,481,000 22,380,598,000 22,331,119,000 22,242,375,000 21,780,826,000 22,058,343,000 21,753,001,000 21,158,161,000 20,528,727,000 20,916,780,000 20,833,671,000 19,340,082,000 15,754,193,000 16,092,583,000 15,784,393,000 15,267,939,000  9,716,790,000   
      unrealized income on investments
     -4,000 17,000 -8,000                                  
      income tax expense
       -1,015,000 -392,000 -2,649,000 -91,000 -38,000 -54,000 -3,854,000 9,000 -54,000 -21,000 -689,000 -709,000 -32,000 -325,000 1,137,000  312,000                  
      other comprehensive income
                                         
      unrealized gain on investments
         -180,000 267,000 6,000 -49,000 146,000 20,000 -109,000 62,000   13,000                      
      other comprehensive
                                         
      unrealized (loss) on investments
                 48,000 -99,000                       
      operating expense:
                                         
      research and development expense
                    12,696,000 8,640,000 11,923,000 12,124,000                  
      selling, general and administrative expense
                    21,300,000 16,529,250 21,624,000 22,304,000                  
      other income
                    -2,000                     
      unrealized gain on marketable securities
                    -44,000 -66,750 -41,000 -98,000 -128,000 -221,000 -268,000 449,000 35,000 -27,000 22,000 281,000          
      net loss per ordinary share basic and diluted
                    -1,250 -922.5 -1,350 -1,170 -1,170 -1,130 -1,310 -1,440 1,790 -812.5 -1,060 -1,080  825 1,280 1,140 880  327.5 20  
      revenues
                        7,485,000 7,966,000 3,461,000 372,000    18,000   283,000 364,000 481,000 327,000 327,000 7,812,000  
      cost of revenues
                        897,000 652,000 309,000 48,000       1,055,000 318,000 430,000 287,000 287,000 295,000  
      other comprehensive income:
                                         
      general and administrative expenses
                             19,745,000 13,972,000 13,775,000 12,707,000 12,552,000 10,743,000 10,207,000 6,069,000 3,437,000 3,437,000 2,199,000 2,300,000 
      realized loss on sale of short-term investment
                                 25,000   100,000     
      interest and other income (expenses)
                               1,276,000          
      finance income
                                -989,000         
      loss per ordinary share basic and diluted
                                1,110        700 
      interest and other expenses
                                 -330,750 -556,000 -408,000      
      finance (expenses) income
                                     91,000    
      income per ordinary share
                                         
      basic
                                     -740    
      diluted
                                     -740    
      weighted-average number of ordinary shares outstanding
                                         
      basic
                                     13,612,814,000    
      diluted
                                     13,612,814,000    
      finance expenses (income)
                                      30,500 -5,000 248,000 
      weighted-average number of ordinary shares outstanding used in computating basic and diluted loss per ordinary share
                                       13,051,117,000 9,204,405,000 
                                         
    Balance Sheets:
    Quarterly
    Annual
      Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-08-14 2018-06-30 2018-05-15 2018-03-31 2018-03-15 2017-12-31 2017-11-14 2017-09-30 2017-08-14 2017-06-30 
                                               
        assets
                                               
        current assets:
                                               
        cash and cash equivalents
      109,968,000 110,745,000 90,039,000 92,904,000 104,033,000 171,987,000 124,916,000 219,972,000 131,439,000 95,002,000 119,305,000 20,127,000 36,540,000 55,408,000 28,686,000 80,690,000 105,379,000 44,360,000 55,337,000 63,322,000 40,492,000 52,864,000 24,565,000 36,350,000 26,468,000 49,688,000 66,147,000 90,424,000 246,692,000 101,318,000 109,483,000 119,109,000 119,109,000 127,460,000 127,460,000 36,999,000 36,999,000 79,171,000 79,171,000 77,093,000 77,093,000 
        marketable securities
      30,306,000 9,711,000 36,994,000 64,050,000 91,857,000 64,698,000 124,659,000 21,106,000 32,606,000 41,966,000 28,114,000 27,174,000 28,514,000 44,556,000 67,225,000 31,048,000 31,065,000 44,779,000 50,872,000 57,710,000 35,417,000 49,154,000 95,058,000 88,773,000 92,623,000 97,389,000 92,046,000 98,739,000              
        restricted cash
      1,327,000 1,350,000 1,347,000 1,082,000 1,076,000 1,076,000 1,073,000 825,000 823,000 821,000 817,000 816,000 814,000 813,000 812,000 811,000 550,000 1,226,000 1,226,000 1,225,000 1,225,000 1,226,000 1,224,000 1,224,000 1,223,000 523,000                
        accounts receivable
      55,412,000 33,082,000 19,703,000 19,649,000 19,638,000 20,302,000 22,802,000 17,415,000 14,158,000 15,443,000 12,847,000 15,505,000 12,493,000 12,704,000 9,429,000 11,595,000 9,499,000 11,717,000 7,784,000 9,512,000 6,301,000 7,047,000 2,810,000 402,000       112,000 232,000 232,000 4,000 4,000   34,000 34,000 10,000 10,000 
        inventories
      20,921,000 16,464,000 8,341,000 7,128,000 7,590,000 9,227,000 7,594,000 7,442,000 7,243,000 5,673,000 5,002,000 4,988,000 5,466,000 4,325,000 4,862,000 5,047,000 4,756,000 4,832,000 3,808,000 3,421,000                      
        prepaid expenses and other current assets
      19,530,000 14,672,000 12,122,000 12,055,000 12,983,000 8,845,000 14,053,000 12,208,000 10,491,000 10,281,000 16,038,000 12,723,000 12,146,000 11,101,000 10,580,000 10,433,000     6,316,000 3,364,000 4,335,000 2,069,000 1,552,000 1,034,000 1,160,000 1,724,000 1,196,000 672,000 1,679,000 1,024,000 1,024,000 726,000 726,000 958,000 958,000 910,000 910,000 704,000 704,000 
        total current assets
      237,464,000 186,024,000 168,546,000 196,868,000 237,177,000 276,135,000 295,097,000 278,968,000 196,760,000 169,186,000 182,123,000 81,333,000 95,973,000 128,907,000 121,594,000 139,624,000 160,524,000 114,390,000 125,140,000 140,498,000 93,082,000 115,619,000 129,338,000 129,943,000 121,866,000 148,634,000 159,876,000 191,194,000 248,295,000 102,243,000 111,471,000 120,704,000 120,704,000 128,736,000 128,736,000 74,472,000 74,472,000 80,449,000 80,449,000 78,302,000 78,302,000 
        non-current assets:
                                               
        property and equipment
      616,000 637,000 695,000 688,000 627,000 655,000 608,000 580,000 566,000 689,000 823,000 910,000 1,103,000 1,297,000 1,519,000 1,605,000 1,777,000 1,967,000 1,978,000 2,001,000 2,142,000 2,046,000 1,725,000 1,401,000 991,000 977,000 893,000 909,000 929,000 948,000 992,000 718,000 718,000 637,000 637,000 805,000 805,000 710,000 710,000 707,000 707,000 
        restricted deposit
      177,000 177,000 177,000 177,000 176,000 176,000 175,000 175,000 226,000 225,000 225,000 224,000 224,000 223,000 223,000 223,000 223,000 223,000 223,000 223,000 223,000 223,000 223,000 223,000 223,000 223,000 523,000 307,000 407,000 253,000 197,000 197,000 197,000 197,000 197,000 198,000 198,000 197,000 197,000 97,000 97,000 
        right of use assets
      7,940,000  8,489,000 5,551,000 4,753,000  1,052,000 1,250,000 1,443,000  1,905,000 2,107,000 2,329,000 2,452,000 2,666,000 2,116,000                          
        other non-current assets
      7,493,000 5,161,000 6,759,000 801,000 371,000 589,000 370,000 673,000 1,098,000 2,038,000 2,050,000 2,817,000 3,160,000 2,740,000 2,471,000 1,900,000 1,572,000 1,311,000 1,773,000 1,103,000 66,000 66,000 55,000  279,000 264,000 2,423,000 2,557,000 2,777,000 317,000 14,000     244,000 244,000     
        total assets
      253,690,000 200,455,000 185,046,000 208,717,000 247,618,000 285,711,000 301,943,000 281,849,000 200,574,000 178,311,000 193,633,000 95,361,000 112,954,000 135,619,000 128,473,000 146,141,000 165,715,000 119,746,000 134,603,000 153,768,000 97,414,000 122,005,000 139,893,000 161,077,000 166,929,000 202,388,000 226,753,000 238,566,000 252,052,000 103,559,000 112,558,000 121,502,000 121,502,000 129,402,000 129,402,000 75,550,000 75,550,000 81,188,000 81,188,000 79,038,000 79,038,000 
        liabilities and shareholders' deficit
                                               
        current liabilities:
                                               
        accounts payable and accrued expenses
      35,346,000 27,717,000 26,173,000 30,962,000 30,322,000 27,431,000 19,685,000 23,754,000 18,158,000 16,538,000 14,083,000 16,403,000 17,130,000 12,383,000 9,356,000 8,647,000  12,102,000   10,558,000 10,023,000 8,492,000 9,203,000 8,500,000 11,186,000 7,880,000 7,071,000 5,942,000 8,540,000 6,291,000 5,655,000 5,655,000 4,048,000 4,048,000 4,435,000 4,435,000 3,488,000 3,488,000 3,543,000 3,543,000 
        employee related accrued expenses
      9,837,000 13,516,000 11,114,000 11,646,000 6,967,000 10,570,000 9,029,000 6,849,000 4,985,000 10,814,000 8,152,000 6,721,000 4,919,000 8,257,000 6,625,000 6,428,000  6,948,000   4,712,000 9,554,000 7,791,000 5,744,000 4,075,000 6,711,000 5,082,000 3,706,000 3,334,000 4,925,000 2,684,000 2,211,000 2,211,000 1,291,000 1,291,000 1,950,000 1,950,000 1,139,000 1,139,000 1,112,000 1,112,000 
        other current liabilities
      5,452,000 5,185,000 4,957,000 4,940,000 4,711,000 7,948,000 4,073,000 3,620,000 3,197,000 3,860,000 3,553,000 3,641,000 3,185,000 3,276,000 3,018,000 2,965,000 4,009,000 3,330,000 2,268,000 1,941,000 1,735,000 1,859,000 1,335,000 1,476,000 1,632,000 1,585,000 1,126,000 1,067,000 1,001,000             
        total current liabilities:
      50,635,000 46,418,000 42,244,000 47,548,000 42,000,000 45,949,000 32,787,000 34,223,000 26,340,000 31,212,000 25,788,000 26,765,000 25,234,000 23,916,000 18,999,000 18,040,000 19,091,000 22,380,000 19,806,000 19,056,000 17,005,000 21,436,000 17,618,000                   
        non-current liabilities:
                                               
        prepaid forward obligation
      128,228,000 127,276,000 126,067,000 124,833,000 123,336,000 121,387,000 118,526,000 115,880,000 112,947,000 109,722,000 107,276,000 104,507,000 101,912,000 98,923,000 96,192,000 93,461,000 89,782,000 85,713,000 79,927,000 74,802,000                      
        long-term debt
      189,530,000 122,210,000 122,111,000 122,508,000 122,108,000 121,734,000 121,709,000 97,813,000 97,590,000 98,551,000 98,518,000 98,296,000 97,941,000 97,537,000 71,870,000 71,196,000 70,797,000                         
        long-term lease liabilities
      5,647,000 6,122,000 6,241,000 3,413,000 2,841,000 1,653,000 212,000 425,000 637,000 844,000 1,026,000 1,209,000 1,403,000 1,586,000 1,856,000 1,515,000  398,000                        
        uncertain tax positions liability
      3,903,000 3,903,000 3,791,000 3,791,000 3,791,000 3,791,000 3,194,000 3,194,000 3,194,000 3,194,000 3,018,000 3,018,000 3,018,000 3,018,000 2,842,000 2,842,000 2,842,000 2,842,000 2,717,000 2,717,000 2,717,000 2,717,000                    
        total liabilities
      377,943,000 305,929,000 300,454,000 302,093,000 294,076,000 294,514,000 276,428,000 251,535,000 240,708,000 243,523,000 235,626,000 233,795,000 229,508,000 224,980,000 191,759,000 187,054,000 182,789,000 111,333,000 103,066,000 97,497,000 20,923,000 25,650,000 19,366,000 18,417,000 16,475,000 22,086,000 15,837,000 13,787,000 12,461,000 13,465,000 8,975,000 7,952,000 7,952,000 5,535,000 5,535,000 7,035,000 7,035,000 4,927,000 4,927,000 4,966,000 4,966,000 
        commitments and contingencies
                                               
        shareholders' deficit:
                                               
        ordinary shares, nis 0.01 par value...
      134,000 133,000 128,000 126,000 126,000 115,000 115,000 112,000 99,000 89,000 84,000 64,000 64,000 63,000 63,000 62,000 62,000 61,000 61,000 61,000 61,000 60,000 60,000 60,000 58,000 57,000 57,000 57,000 56,000 44,000 44,000 43,000 43,000 42,000 42,000  37,000     
        additional paid-in capital
      858,895,000 854,090,000 817,793,000 806,497,000 803,467,000 797,248,000 793,874,000 775,270,000 671,438,000 614,035,000 611,389,000 493,109,000 490,744,000 487,787,000 485,041,000 481,485,000 478,646,000 475,698,000 470,341,000 464,823,000 458,723,000 452,525,000 445,950,000 438,999,000 415,895,000 407,986,000 399,600,000 391,233,000 383,850,000 212,921,000 202,693,000 192,129,000 192,129,000 184,421,000 184,421,000 115,692,000 115,692,000 113,354,000 113,354,000 110,867,000 110,867,000 
        accumulated deficit
      -983,290,000 -959,716,000 -933,352,000 -900,005,000 -850,065,000 -806,222,000 -768,710,000 -745,037,000 -711,634,000 -679,348,000 -653,332,000 -631,453,000 -607,317,000 -577,104,000 -548,235,000 -522,404,000 -495,713,000 -467,321,000 -438,869,000 -408,658,000 -382,436,000 -356,501,000 -325,975,000 -297,159,000 -265,810,000 -228,017,000 -189,044,000 -166,792,000 -144,315,000 -122,871,000 -99,154,000 -78,622,000 -78,622,000 -60,596,000 -60,596,000 -47,214,000 -47,214,000 -37,128,000 -37,128,000 -36,830,000 -36,830,000 
        accumulated other comprehensive income
      8,000 19,000 23,000 6,000 14,000 56,000 236,000 -31,000  12,000       -69,000 -25,000 4,000 45,000 143,000 271,000 492,000 760,000 311,000 276,000 303,000 281,000              
        total shareholders' deficit
      -124,253,000 -105,474,000 -115,408,000 -93,376,000 -46,458,000 -8,803,000   -40,134,000 -65,212,000 -41,993,000 -138,434,000 -116,554,000                             
        total liabilities and shareholders' deficit
      253,690,000 200,455,000 185,046,000 208,717,000 247,618,000 285,711,000   200,574,000 178,311,000 193,633,000 95,361,000 112,954,000                             
        right-of-use assets
       8,456,000    3,134,000    1,671,000                                
        liabilities and shareholders' equity
                                               
        shareholders' equity
                                               
        total shareholders' equity
            25,515,000 30,314,000       -63,286,000 -40,913,000 -17,074,000 8,413,000 31,537,000 56,271,000 76,491,000 96,355,000                    
        total liabilities and shareholders' equity
            301,943,000 281,849,000       128,473,000 146,141,000 165,715,000 119,746,000 134,603,000 153,768,000 97,414,000 122,005,000                    
        accumulated other comprehensive loss
              -37,000  -134,000 -154,000 -45,000 -107,000 -155,000 -56,000                          
        total shareholders' (deficit) equity
                   -89,361,000                            
        total liabilities and shareholders' (deficit) equity
                   135,619,000                            
        prepaid expense and other current assets
                      9,275,000 7,476,000 6,113,000 5,308,000                      
        right of use asset
                      945,000 1,180,000 1,418,000 1,653,000 1,901,000 2,158,000 2,652,000 3,011,000 3,433,000 3,735,000                
        accounts payable and accrued expense
                      9,936,000  11,062,000 10,342,000                      
        employee related accrued expense
                      5,146,000  6,476,000 6,773,000                      
        long-term lease liability
                      277,000  616,000 922,000 1,201,000 1,497,000 1,748,000 1,994,000 2,268,000 2,604,000 1,749,000 1,943,000 2,184,000             
        shareholders' equity:
                                               
        inventory
                          3,331,000 1,964,000 1,346,000 1,125,000        142,000 142,000 349,000 349,000 316,000 316,000 137,000 137,000 398,000 398,000 
        liabilities and shareholder's equity
                                               
        total shareholders’ equity
                            120,527,000 142,660,000 150,454,000 180,302,000 210,916,000 224,779,000 239,591,000 90,094,000 103,583,000 113,550,000 113,550,000 123,867,000 123,867,000 68,515,000 68,515,000 76,261,000 76,261,000 74,072,000 74,072,000 
        total liabilities and shareholders’ equity
                            139,893,000 161,077,000 166,929,000 202,388,000 226,753,000 238,566,000 252,052,000 103,559,000 112,558,000 121,502,000 121,502,000 129,402,000 129,402,000 75,550,000 75,550,000 81,188,000 81,188,000 79,038,000 79,038,000 
        non-current assets
                                               
        total current liabilities
                             16,423,000 14,207,000 19,482,000 14,088,000 11,844,000 10,277,000 13,465,000 8,975,000 7,952,000 7,952,000 5,535,000 5,535,000 7,035,000 7,035,000 4,927,000 4,927,000 4,966,000 4,966,000 
        shareholders’ equity:
                                               
        non-current liability:
                                               
        total non-current liabilities
                                1,749,000 1,943,000 2,184,000             
        short-term investments
                                         36,001,000 36,001,000     
        deferred revenues
                                     86,000 86,000 196,000 196,000 650,000 650,000 300,000 300,000 311,000 311,000 
        liabilities and shareholders’ equity
                                               
        proceeds from exercise of warrants for preferred shares
                                               
        warrants for preferred shares
                                               
        ordinary shares, nis 0.01 par value: 100,000,000 and 17,600,000 shares authorized at december 31, 2017 and 2016, respectively; 13,751,390 and 2,305,743 shares issued and outstanding at december 31, 2017 and 2016, respectively.
                                         37,000      
        series a and a-1 preferred shares, nis 0.01 par value: 0 and 14,400,000 shares authorized at december 31, 2017 and 2016, respectively; 0 and 5,193,427 shares issued and outstanding at december 31, 2017 and 2016, respectively.
                                               
        non-current liabilities
                                               
        series a and a-1 preferred shares, nis 0.01 par value: 0 and 14,400,000 shares authorized at december 31, 2017 and 2016, respectively; 0 and 5,193,427 shares issued and outstanding at december 31, 2017 and 2016, respectively
                                               
        ordinary shares, nis 0.01 par value: 100,000,000 shares and 17,600,000 shares authorized at september 30, 2017 and december 31, 2016, respectively; 13,178,400 and 2,305,743 issued and outstanding at september 30, 2017 and december 31, 2016, respectively.
                                           35,000 35,000   
        preferred a and preferred a-1 shares, nis 0.01 par value: 14,400,000 shares authorized at december 31, 2016, 5,193,427 shares issued and outstanding at december 31, 2016.
                                               
        ordinary shares, nis 0.01 par value: 100,000,000 shares and 17,600,000 shares authorized at june 30, 2017 and december 31, 2016, respectively; 13,009,504 and 2,305,743 issued and outstanding at june 30, 2017 and december 31, 2016, respectively.
                                             35,000 35,000 
      Cashflow Statements:
      Quarterly
      Annual
        Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-05-15 2018-03-31 2017-11-14 2017-09-30 2017-08-14 2017-06-30 
                                              
          cash flows from operating activities
                                              
          net loss
        -23,574,000 -26,364,000 -33,347,000 -49,940,000 -43,843,000 -37,512,000 -23,673,000 -33,403,000 -32,286,000 -26,016,000 -21,879,000 -24,136,000 -30,213,000 -28,869,000 -25,831,000 -26,691,000 -28,392,000 -28,452,000 -30,211,000 -26,222,000 -25,935,000 -30,526,000 -28,816,000 -31,349,000 -37,793,000 -38,973,000 -22,252,000 -22,477,000 -21,444,000 -23,717,000 -20,532,000  -13,382,000  -9,914,000  -9,616,000  
          adjustment to reconcile net loss to net cash from operating activities:
                                              
          depreciation and amortization
        75,000 75,000 80,000 80,000 72,000 68,000 68,000 70,000 123,000 190,000 186,000 209,000 217,000 236,000 239,000 234,000 215,000 213,000 217,000 210,000 191,000 121,000 117,000 96,000 82,000 108,000 65,000 60,000 63,000          
          accrued financing on prepaid forward obligation
        1,059,000 1,270,000 1,472,000 2,012,000 -1,889,000 6,064,000 3,074,000 3,340,000 2,599,000 2,790,000 2,732,000 3,109,000 2,873,000 2,988,000 2,660,000 4,070,000 4,289,000 6,265,000 6,253,000                    
          amortization on marketable securities
        26,000           -310,000 -354,000 -405,000 -262,000 119,000 50,000 133,000 162,000 -10,000 191,000                  
          share-based compensation
        4,627,000 3,130,000 3,027,000 2,733,000 3,069,000 3,303,000 3,489,000 3,560,000 2,756,000 2,611,000 2,224,000 2,222,000 2,286,000 2,368,000 2,440,000 2,823,000 2,949,000 5,357,000             9,515,000 7,709,000 4,541,000 4,541,000 4,031,000 4,031,000 1,873,000 1,873,000 
          amortization of discount on long-term debt
        1,974,000 99,000 -397,000 400,000 374,000 25,000 -592,000 223,000 -961,000 33,000 222,000 355,000 404,000 677,000                         
          amortization of right of use assets
        577,000  559,000 516,000 425,000  198,000 193,000 228,000  229,000 222,000 218,000 214,000 196,000                        
          acquisitions of ipr&d
         3,128,000                                  
          changes in operating assets and liabilities:
                                              
          inventory
        -4,457,000 -8,123,000 -1,213,000 462,000 1,637,000 -1,633,000 -152,000 -199,000 -1,570,000 -671,000 -14,000 477,000 -1,140,000 283,000 -165,000 -556,000 76,000 -1,024,000 -387,000 -90,000 -1,367,000 -618,000                 
          accounts receivable
        -22,330,000 -13,379,000 -54,000 -11,000 664,000 2,500,000 -5,387,000 -3,257,000 1,285,000 -2,596,000 2,658,000 -3,012,000 211,000 -3,275,000 2,166,000 -2,096,000 2,218,000 -3,934,000 1,728,000 -3,211,000 746,000 -4,237,000                 
          prepaid expenses and other current assets
        -4,858,000 -2,550,000 -67,000 928,000 -4,138,000 5,208,000 -1,845,000 -1,717,000 -210,000 5,757,000 -3,315,000 -577,000 -1,045,000 -522,000 -146,000      -2,952,000 931,000                 
          other non-current assets
        -2,332,000 1,598,000 -5,958,000 -430,000 218,000 -219,000 303,000 425,000 940,000 12,000 767,000 344,000 -421,000 -269,000 -556,000 -275,000 -169,000 553,000 -547,000                    
          accounts payable and accrued expenses
        7,629,000 1,544,000 -4,789,000 640,000 2,891,000 7,746,000 -4,069,000 5,596,000 1,620,000 2,455,000 -2,320,000 -727,000 4,747,000 3,027,000 708,000      535,000 1,261,000                 
          employee related accrued expenses
        -3,679,000 2,402,000 -532,000 4,679,000 -3,603,000 1,541,000 2,180,000 1,864,000 -5,829,000 2,662,000 1,431,000 1,802,000 -3,338,000 1,632,000 197,000      -4,842,000 1,763,000                 
          other current liabilities
         -1,000 -263,000 -421,000 483,000         1,000 -1,005,000 301,000 642,000 -790,000                    
          lease liabilities
        -53,000 1,333,000 -628,000 -606,000 -738,000 -408,000 -184,000 -195,000 -247,000 -221,000 -262,000 -252,000 -252,000 -269,000 -282,000                        
          net cash from operating activities
        -45,316,000 -38,325,000 -42,270,000 -39,825,000 -42,024,000 -13,619,000 -27,664,000 -23,748,000 -31,735,000 -12,996,000 -17,299,000 -20,274,000 -25,807,000 -21,752,000 -17,612,000 -24,199,000 -23,996,000 -20,070,000 -18,476,000 -18,945,000 -27,401,000 -21,242,000 -25,080,000 -23,929,000 -35,635,000 -26,000,000 -12,528,000 -14,555,000 -17,934,000 -10,284,000 -9,279,000 -8,147,000 -9,624,000 -9,624,000 -3,609,000 -3,609,000 -6,206,000 -6,206,000 
          capital expenditures
        -54,000 -17,000 -87,000 -141,000 -44,000 -115,000 -96,000  -56,000 -100,000 -15,000 -23,000 -13,000 -153,000 -63,000 -25,000 -202,000 -194,000 -69,000 -287,000 -660,000 -287,000 -96,000 -49,000 -44,000 -24,000 -332,000 -132,000 -72,000 -72,000 -118,000 -118,000   
          free cash flows
        -45,370,000 -38,342,000 -42,357,000 -39,966,000 -42,068,000 -13,734,000 -27,760,000 -23,748,000  -13,052,000 -17,399,000 -20,289,000 -25,830,000 -21,765,000 -17,765,000 -24,262,000 -24,021,000 -20,272,000 -18,670,000 -19,014,000 -27,688,000 -21,242,000 -25,740,000 -24,216,000 -35,731,000 -26,000,000 -12,577,000 -14,555,000 -17,978,000 -10,308,000 -9,611,000 -8,279,000 -9,696,000 -9,696,000 -3,727,000 -3,727,000   
          cash flows from investing activities
                                              
          purchases of marketable securities
        -24,780,000 -539,000 -8,721,000 -1,789,000 -66,351,000 -9,229,000    -14,823,000 -10,833,000 -24,176,000     -9,939,000                    
          maturities of marketable securities
        4,146,000 28,273,000 40,206,000 30,336,000 40,432,000 69,965,000 12,140,000 12,082,000 13,518,000 3,535,000 11,334,000 3,735,000 30,469,000 23,121,000 27,669,000 -88,000 13,621,000 9,631,000 18,330,000 10,984,000 15,311,000 49,638,000 13,893,000 38,111,000 22,499,000 38,490,000             
          purchases of property and equipment
        -54,000 -17,000 -87,000 -141,000 -44,000 -115,000 -96,000   -56,000 -100,000 -15,000 -23,000 -13,000 -153,000 -63,000 -25,000 -202,000 -194,000 -69,000 -287,000  -660,000 -287,000 -96,000  -49,000            
          net cash from investing activities
        -20,688,000 27,717,000 31,398,000 28,406,000 -25,963,000 60,621,000 -106,750,000 11,998,000 13,518,000 -11,344,000 401,000 3,720,000 6,270,000 23,108,000 -35,493,000 -151,000 13,596,000 9,125,000 10,660,000 -30,740,000 15,024,000 49,465,000 13,234,000 17,514,000 13,025,000 9,296,000 -12,659,000 -142,186,000 -44,000 -26,000 -333,000 -183,000 35,829,000 35,829,000 -223,000 -223,000 -103,000 -103,000 
          cash flows from financing activities
                                              
          principal payments on finance leases
        -321,000                                      
          proceeds from exercise of options into ordinary shares
        179,000 1,343,000 302,000 297,000 30,000 71,000 115,000   40,000 19,000 143,000 671,000 378,000 1,117,000   3,000 54,000 4,000 89,000 148,000 210,000 293,000 321,000 1,126,000 685,000 1,532,000          
          proceeds from issuance of long-term debt
        65,346,000             24,990,000 -38,000 70,831,000                      
          proceeds from ordinary shares issuances, net of issuance costs
         31,831,000                                     
          net cash from financing activities
        65,204,000 31,316,000 8,272,000 296,000 34,000 71,000 39,606,000 100,285,000 54,657,000 40,000 116,077,000 143,000 671,000 25,368,000 1,101,000 -77,000 70,742,000 -32,000 -168,000 72,515,000 4,000 78,000 61,000 16,298,000 90,000 245,000 1,126,000 373,000 163,506,000 2,200,000 -14,000 -21,000 64,256,000 64,256,000 61,641,000 61,641,000 62,040,000 62,040,000 
          decrease in cash and cash equivalents
        -800,000                    -12,373,000 28,301,000                 
          cash, cash equivalents and restricted cash at beginning of period
        112,095,000  173,062,000  95,822,000  56,220,000  1,000 -1,000 45,587,000  54,090,000                  
          cash, cash equivalents and restricted cash at end of period
        111,295,000  -2,600,000 -11,123,000 105,109,000  -94,808,000 88,535,000 132,262,000  99,179,000 -16,411,000 37,354,000  -52,003,000 -24,428,000 105,929,000  -7,984,000 22,830,000 41,717,000                  
          supplemental disclosures of non-cash activities
                                              
          right-of-use assets obtained in exchange for new operating and finance lease liabilities
        60,000                                      
          accretion on marketable securities
         -75,000 -160,000 -866,000 -774,000                                  
          amortization of right-of-use assets
                                              
          restricted deposit
           -1,000                                
          uncertain tax positions
                                              
          proceeds from issuance of long-term debt, net of issuance costs
                                              
          proceeds from pre-funded warrant issuance, net of issuance costs
                                           
          increase in cash and cash equivalents
         20,708,000 -2,600,000 -11,123,000 -67,953,000 47,073,000 -94,808,000 88,535,000 36,440,000 -24,300,000 99,179,000 -16,411,000 -18,866,000 26,724,000 -52,004,000 -24,427,000 60,342,000 -10,977,000 -7,984,000     9,883,000 -22,520,000 -16,459,000 -24,061,000 -156,368,000 145,528,000 -8,110,000 -9,626,000 -8,351,000 90,461,000 90,461,000 57,809,000 57,809,000 55,731,000 55,731,000 
          cash, cash equivalents and restricted cash at beginning of year
                                              
          cash, cash equivalents and restricted cash at end of year
                                              
          right of use assets obtained in exchange for new operating lease liabilities
          3,498,000 1,313,000 2,045,000      27,000 95,000                         
          proceeds from ordinary shares issuance, net of issuance costs
            4,000                                 
          right-of-use assets obtained in exchange for new operating lease liabilities
                                              
          (accretion) on marketable securities
              -1,074,000 -298,000 -183,000 -412,000                             
          proceeds from ordinary share issuance, net of issuance costs
               81,509,000 54,657,000                              
          inventory obsolescence
                     255,000 350,000                        
          proceeds from pre-funded warrant issuance, net of 1,654 of issuance costs
                                             
          proceeds from ordinary share issuance, net of 2,288 of issuance costs
                                             
          issuance cost related to at-the-market issuances
                     -16,000 -55,000 -89,000 -17,000 -116,000   -11,000                 
          non-cash issuance cost
                        3,000            312,000          
          sales of marketable securities
                                             
          proceeds from prepaid forward arrangement
                         -15,000 -55,000                    
          interest expense on long-term debt
                       121,000 282,000                      
          non-cash new lease liabilities
                       1,413,000 6,000  -16,000 -20,000  22,000 -43,000 72,000              
          amortization of right of use asset
                        241,000 238,000 235,000 232,000 237,000 494,000 381,000 379,000 374,000              
          lease liability
                        -286,000  -262,000 -252,000 -400,000 -384,000 -409,000 -387,000 -361,000  -246,000 -201,000 -173,000          
          prepaid expense and other current assets
                        -1,800,000 -1,362,000 -805,000                    
          accounts payable and accrued expense
                        -2,169,000 966,000 713,000                    
          employee related accrued expense
                        -1,801,000 472,000 -297,000                    
          purchase of marketable securities
                             -1,000 1,000 -20,310,000 -9,378,000 -28,834,000             
          issuances of ordinary shares, net of issuance expenses
                                              
          purchase of property and equipment
                                    -44,000 -24,000 -332,000 -132,000 -72,000 -72,000 -118,000 -118,000 -98,000 -98,000 
          accrued issuance cost
                                              
          new lease liabilities
                                              
          issuances of ordinary shares, net of issuance expense
                                              
          exercise of options
                                   -513,000 515,000          
          stock-based compensation
                           6,046,000 6,195,000 6,526,000 6,763,000 7,119,000 7,617,000 8,065,000 7,243,000 7,212,000 7,447,000          
          non-cash purchases of property and equipment
                                              
          current tax payable
                                              
          change in restricted deposit
                                 -168,000   -2,000 -1,000    -105,000 -105,000 -5,000 -5,000 
          issuance of ordinary shares, net of issuance expenses
                             -32,000          60,926,000 60,926,000 61,654,000 61,654,000 
          issuance cost
                                              
          cash flows from operating activities:
                                              
          amortization/accretion on marketable securities
                              152,000 136,000 98,000 -75,000 -330,000            
          cash flows from investing activities:
                                              
          cash flows from financing activities:
                                              
          cash, cash equivalents and restricted cash at beginning of the period
                              50,211,000              
          cash, cash equivalents and restricted cash at end of the period
                              -11,785,000 9,883,000 27,691,000              
          supplemental disclosures of non-cash activities:
                                              
          increase in inventory
                                        -33,000 -33,000   -293,000 -293,000 
          increase in accounts receivable
                                         -4,000     
          increase in prepaid expenses and other current assets
                               -517,000 -518,000              
          decrease in accounts payable and accrued expenses
                               452,000 -2,498,000    -2,440,000          
          decrease in employee related accrued expenses
                               1,669,000 -2,636,000    -1,591,000    -659,000 -659,000     
          supplemental disclosures of non-cash investing and financing activities:
                                              
          non-cash purchase of property and equipment
                                              
          issuance cost for shelf filing
                                -203,000              
          fair value adjustment of warrants for preferred shares
                                          168,000 168,000 168,000 168,000 
          realized loss on sale of short-term investment
                                     100,000 100,000     
          change in lease liability
                                              
          decrease in inventory
                                     142,000    -32,000    
          decrease in accounts receivable
                                      120,000  -4,000  49,000  73,000 73,000 
          decrease in prepaid expenses and other current assets
                                 126,000   -41,000 -11,000   232,000  -514,000  -308,000  
          increase in accounts payable and accrued expenses
                                 3,118,000 809,000   2,147,000 636,000 1,628,000 -206,000 -206,000 1,704,000 1,704,000 1,031,000 1,031,000 
          increase in deferred revenues
                                     -86,000 -110,000 -454,000 -454,000 300,000 300,000   
          increase in employee related accrued expenses
                                 1,629,000 1,376,000   2,241,000 473,000    452,000 452,000 425,000 425,000 
          sale of short-term investments
                                              
          proceeds from exercise of warrants for preferred shares
                                              
          issuance cost for secondary offering
                                              
          cash, cash equivalents and restricted cash at beginning of the year
                                            
          cash, cash equivalents and restricted cash at end of the year
                                 -16,459,000 -24,061,000 -156,368,000 247,099,000          
          exercise of warrants to preferred shares
                                              
          exchange rate differences
                                              
          right of use asset
                                  245,000 246,000 245,000          
          decrease in deferred revenues
                                              
          sale of short-term investment
                                      35,901,000 35,901,000     
          short-term investments
                                              
          issuance of ordinary shares, net of issurance expenses
                                    161,974,000          
          cash, cash equivalents and restriced cash at beginning of the year
                                    101,571,000          
          payment of deferred equity offering cost
                                              
          adjustments required to reconcile net loss to net cash from operating activities:
                                              
          depreciation and disposals
                                      58,000 51,000 240,000 240,000     
          exchange rates differences
                                      1,000 1,000 -2,000 -2,000 -2,000 -2,000 
          issuance of ordinary shares in public offering, net of issuance expenses
                                      -14,000 -21,000 64,256,000 64,256,000     
          proceeds from exercise of warrants to preferred shares
                                          382,000 382,000 382,000 382,000 
          balance of cash and cash equivalents at beginning of the year
                                      36,999,000 36,999,000     
          balance of cash and cash equivalents at end of the year
                                      -9,626,000 -8,351,000 127,460,000 127,460,000     
          exercise of warrants into preferred shares
                                          4,732,000 4,732,000 4,732,000 4,732,000 
          net income
                                         -13,382,000  -9,914,000  -9,616,000 
          adjustments required to reconcile net income to net cash from operating activities:
                                              
          decrease (increase) in inventory
                                           -32,000   
          non cash issuance cost
                                        21,000 21,000   728,000 728,000 
          decrease (increase) in prepaid expenses and other current assets
                                         232,000  -514,000  -308,000 
          depreciation
                                          149,000 149,000 132,000 132,000 
          in process r&d
                                              
          share based compensation
                                              
          changes in operating asset and liabilities:
                                              
          proceeds from issuance of preferred shares from 2014 share purchase agreement net of issuance cost
                                              
          purchase of ip r&d in consideration for preferred a shares
                                              
          exercise of options into ordinary shares
                                          333,000 333,000 4,000 4,000 
          balance of cash and cash equivalents at beginning of the period
                                          21,362,000 21,362,000 21,362,000 21,362,000 
          balance of cash and cash equivalents at end of the period
                                          79,171,000 79,171,000 77,093,000 77,093,000 
          decrease (increase) in accounts receivable
                                           49,000   
          deferred revenues
                                            311,000 311,000 
          non cash purchase of property and equipment