UroGen Pharma Ltd(NASDAQ:URGN)
UroGen Pharma Ltd., a biopharmaceutical company, engages in the development and commercialization novel solutions for specialty cancers and urologic diseases. It offers RTGel, a polymeric biocompatible and reverse thermal gelation hydrogel to improve therapeutic profiles of existing drugs; and Jelmy...
Website: http://www.urogen.com
Founded: 2004
Full Time Employees: 187
Sector: Healthcare
Industry: Biotechnology
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At a glance:
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Quarterly
Annual
| Unit: USD | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-08-14 | 2018-05-15 | 2018-03-15 | 2017-12-31 | 2017-11-14 | 2017-08-14 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
revenue | 50,959,000 | 37,837,000 | 27,482,000 | 24,215,000 | 20,254,000 | 24,565,000 | 25,204,000 | 21,848,000 | 18,781,000 | 23,530,000 | 20,852,000 | 21,139,000 | 17,192,000 | 18,092,000 | 16,097,000 | 16,604,000 | 13,564,000 | 16,174,000 | 11,351,000 | 13,032,000 | |||||||||||||||||
yoy | 151.60% | 54.03% | 9.04% | 10.83% | 7.84% | 4.40% | 20.87% | 3.35% | 9.24% | 30.06% | 29.54% | 27.31% | 26.75% | 11.86% | 41.81% | 27.41% | |||||||||||||||||||||
qoq | 34.68% | 37.68% | 13.49% | 19.56% | -17.55% | -2.54% | 15.36% | 16.33% | -20.18% | 12.84% | -1.36% | 22.96% | -4.97% | 12.39% | -3.05% | 22.41% | -16.14% | 42.49% | -12.90% | ||||||||||||||||||
cost of revenue | 4,139,000 | 3,289,000 | 3,278,000 | 3,550,000 | 2,330,000 | 2,471,000 | 2,453,000 | 2,229,000 | 1,728,000 | 2,286,000 | 2,367,000 | 2,443,000 | 2,265,000 | 2,263,000 | 2,020,000 | 1,846,000 | 1,525,000 | 1,589,000 | 1,244,000 | 1,427,000 | |||||||||||||||||
gross profit | 46,820,000 | 34,548,000 | 24,204,000 | 20,665,000 | 17,924,000 | 22,094,000 | 22,751,000 | 19,619,000 | 17,053,000 | 21,244,000 | 18,485,000 | 18,696,000 | 14,927,000 | 15,829,000 | 14,077,000 | 14,758,000 | 12,039,000 | 14,585,000 | 10,107,000 | 11,605,000 | 6,588,000 | 7,314,000 | 3,152,000 | 324,000 | 18,000 | -772,000 | 46,000 | 51,000 | 40,000 | 40,000 | 7,517,000 | ||||||
yoy | 161.21% | 56.37% | 6.39% | 5.33% | 5.11% | 4.00% | 23.08% | 4.94% | 14.24% | 34.21% | 31.31% | 26.68% | 23.99% | 8.53% | 39.28% | 27.17% | 82.74% | 99.41% | 220.65% | 3481.79% | NaN% | NaN% | 1700.00% | NaN% | NaN% | -60.87% | NaN% | -2030.00% | -99.39% | NaN% | |||||||
qoq | 35.52% | 42.74% | 17.13% | 15.29% | -18.87% | -2.89% | 15.96% | 15.05% | -19.73% | 14.93% | -1.13% | 25.25% | -5.70% | 12.45% | -4.61% | 22.58% | -17.46% | 44.31% | -12.91% | 76.15% | -9.93% | 132.04% | 872.84% | NaN% | NaN% | NaN% | -1778.26% | -9.80% | 27.50% | 0.00% | -99.47% | NaN% | |||||
gross margin % | 91.88% | 91.31% | 88.07% | 85.34% | 88.50% | 89.94% | 90.27% | 89.80% | 90.80% | 90.28% | 88.65% | 88.44% | 86.83% | 87.49% | 87.45% | 88.88% | 88.76% | 90.18% | 89.04% | 89.05% | Infinity% | Infinity% | Infinity% | Infinity% | NaN% | NaN% | NaN% | Infinity% | NaN% | NaN% | -Infinity% | Infinity% | Infinity% | Infinity% | Infinity% | Infinity% | NaN% |
operating expenses: | |||||||||||||||||||||||||||||||||||||
research and development expenses | 15,597,000 | 14,314,000 | 14,008,000 | 18,914,000 | 19,871,000 | 14,894,000 | 11,355,000 | 15,402,000 | 15,494,000 | 11,302,000 | 10,230,000 | 11,584,000 | 12,498,000 | 14,477,000 | 13,093,000 | 12,640,000 | 10,513,000 | 12,405,000 | 10,211,000 | 8,106,000 | 16,588,000 | 20,094,000 | 9,481,000 | 9,996,000 | 9,726,000 | 11,465,000 | 9,574,000 | 8,273,000 | 7,622,000 | 6,761,000 | 6,761,000 | 5,621,000 | 3,651,000 | ||||
selling, general and administrative expenses | 51,486,000 | 39,349,000 | 37,582,000 | 43,199,000 | 34,967,000 | 34,858,000 | 28,941,000 | 30,056,000 | 27,299,000 | 24,551,000 | 21,755,000 | 22,494,000 | 24,474,000 | 21,634,000 | 19,071,000 | 20,833,000 | 22,189,000 | 22,163,000 | 22,065,000 | 24,018,000 | 21,973,000 | ||||||||||||||||
operating income | -20,263,000 | -19,115,000 | -27,386,000 | -41,448,000 | -36,914,000 | -27,658,000 | -17,545,000 | -25,839,000 | -25,740,000 | -14,609,000 | -13,500,000 | -15,382,000 | -22,045,000 | -20,282,000 | -18,087,000 | -18,715,000 | -21,957,000 | -19,915,000 | -23,440,000 | -22,823,000 | -26,114,000 | -27,254,000 | -29,124,000 | -31,800,000 | -38,561,000 | -39,839,000 | -23,453,000 | -23,753,000 | -22,433,000 | -130,343,000 | 21,089,000 | 18,434,000 | 13,640,000 | -10,158,000 | -29,742,000 | 303,000 | 5,951,000 |
yoy | -45.11% | -30.89% | 56.09% | 60.41% | 43.41% | 89.32% | 29.96% | 67.98% | 16.76% | -27.97% | -25.36% | -17.81% | 0.40% | 1.84% | -22.84% | -18.00% | -15.92% | -26.93% | -19.52% | -28.23% | -32.28% | -31.59% | 24.18% | 33.88% | 71.89% | -69.44% | -211.21% | -228.85% | -264.46% | 1183.16% | -170.91% | 5983.83% | 129.21% | ||||
qoq | 6.01% | -30.20% | -33.93% | 12.28% | 33.47% | 57.64% | -32.10% | 0.38% | 76.19% | 8.21% | -12.24% | -30.22% | 8.69% | 12.14% | -3.36% | -14.77% | 10.25% | -15.04% | 2.70% | -12.60% | -4.18% | -6.42% | -8.42% | -17.53% | -3.21% | 69.87% | -1.26% | 5.88% | -82.79% | -718.06% | 14.40% | 35.15% | -234.28% | -65.85% | -9915.84% | -94.91% | |
operating margin % | -39.76% | -50.52% | -99.65% | -171.17% | -182.26% | -112.59% | -69.61% | -118.27% | -137.05% | -62.09% | -64.74% | -72.77% | -128.23% | -112.10% | -112.36% | -112.71% | -161.88% | -123.13% | -206.50% | -175.13% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | Infinity% | Infinity% | Infinity% | -Infinity% | -Infinity% | Infinity% | Infinity% |
financing on prepaid forward obligation | -4,506,000 | -4,655,000 | -4,621,000 | -4,644,000 | -4,583,000 | -6,063,000 | -5,915,000 | -5,773,000 | -5,660,000 | -5,505,000 | -5,479,000 | -5,344,000 | -5,224,000 | -5,081,000 | -4,819,000 | -5,833,000 | -5,826,000 | -7,343,000 | -6,828,000 | -3,120,000 | |||||||||||||||||
interest expense on long-term debt | -4,185,000 | -3,772,000 | -3,373,000 | -4,132,000 | -4,068,000 | -3,892,000 | -2,721,000 | -3,461,000 | -2,447,000 | -3,586,000 | -3,815,000 | -3,761,000 | -3,553,000 | -3,223,000 | -2,694,000 | -2,239,000 | -282,000 | ||||||||||||||||||||
interest and other income | 608,000 | 903,000 | 979,000 | 1,299,000 | 2,114,000 | 2,750,000 | 2,599,000 | 1,708,000 | 1,615,000 | 1,538,000 | 906,000 | 405,000 | 630,000 | 406,000 | 478,000 | 128,000 | -57,000 | 57,000 | 33,000 | 179,000 | 102,000 | 308,000 | 451,000 | 768,000 | 866,500 | 1,201,000 | -358,000 | ||||||||||
income before income taxes | -28,346,000 | -26,639,000 | -34,401,000 | -48,925,000 | -43,451,000 | -34,863,000 | -23,582,000 | -33,365,000 | -32,232,000 | -22,162,000 | -21,888,000 | -24,082,000 | -30,192,000 | -28,180,000 | -25,122,000 | -26,659,000 | -28,067,000 | -27,315,000 | -30,211,000 | -25,910,000 | -10,067,000 | ||||||||||||||||
income tax benefit | 4,772,000 | -88,250 | 1,054,000 | ||||||||||||||||||||||||||||||||||
net income | -23,574,000 | -26,364,000 | -33,347,000 | -49,940,000 | -43,843,000 | -37,512,000 | -23,673,000 | -33,403,000 | -32,286,000 | -26,016,000 | -21,879,000 | -24,136,000 | -30,213,000 | -28,869,000 | -25,831,000 | -26,691,000 | -28,392,000 | -28,452,000 | -30,211,000 | -26,222,000 | -25,935,000 | -30,526,000 | -28,816,000 | -31,349,000 | -37,793,000 | -38,973,000 | -22,252,000 | -22,477,000 | -21,444,000 | -127,597,000 | 20,533,000 | 18,026,000 | 13,382,000 | -10,067,000 | -29,914,000 | 298,000 | 6,199,000 |
yoy | -46.23% | -29.72% | 40.87% | 49.51% | 35.80% | 44.19% | 8.20% | 38.39% | 6.86% | -9.88% | -15.30% | -9.57% | 6.41% | 1.47% | -14.50% | 1.79% | 9.47% | -6.79% | 4.84% | -16.35% | -31.38% | -21.67% | 29.50% | 39.47% | 76.24% | -69.46% | -208.37% | -224.69% | -260.25% | 1167.48% | -168.64% | 5948.99% | 115.87% | ||||
qoq | -10.58% | -20.94% | -33.23% | 13.91% | 16.88% | 58.46% | -29.13% | 3.46% | 24.10% | 18.91% | -9.35% | -20.11% | 4.66% | 11.76% | -3.22% | -5.99% | -0.21% | -5.82% | 15.21% | 1.11% | -15.04% | 5.93% | -8.08% | -17.05% | -3.03% | 75.14% | -1.00% | 4.82% | -83.19% | -721.42% | 13.91% | 34.70% | -232.93% | -66.35% | -10138.26% | -95.19% | |
net income margin % | -46.26% | -69.68% | -121.34% | -206.24% | -216.47% | -152.71% | -93.93% | -152.89% | -171.91% | -110.57% | -104.93% | -114.18% | -175.74% | -159.57% | -160.47% | -160.75% | -209.32% | -175.91% | -266.15% | -201.21% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | Infinity% | Infinity% | Infinity% | -Infinity% | -Infinity% | Infinity% | Infinity% |
statements of comprehensive loss | |||||||||||||||||||||||||||||||||||||
other comprehensive loss | |||||||||||||||||||||||||||||||||||||
unrealized loss on investments | -11,000 | -42,000 | |||||||||||||||||||||||||||||||||||
comprehensive loss | -23,585,000 | -26,368,000 | -33,330,000 | -49,948,000 | -43,885,000 | -37,692,000 | -23,406,000 | -33,397,000 | -32,335,000 | -25,870,000 | -21,859,000 | -24,245,000 | -30,151,000 | -28,821,000 | -25,930,000 | -26,678,000 | -28,436,000 | -28,481,000 | -30,252,000 | -26,320,000 | -26,063,000 | -30,747,000 | -29,084,000 | -30,900,000 | -37,758,000 | -39,000,000 | -22,230,000 | -22,196,000 | |||||||||
net loss per ordinary share - basic and diluted | -470 | -530 | -690 | -1,050 | -920 | -600 | -550 | -910 | -970 | -660 | -680 | -1,030 | -1,300 | -1,250 | -1,130 | -1,180 | |||||||||||||||||||||
weighted-average number of shares outstanding used in computation of basic and diluted loss per ordinary share | 50,182,758,000 | 48,116,098,000 | 48,057,386,000 | 47,739,816,000 | 47,422,119,000 | 42,876,737,000 | 43,100,237,000 | 36,821,915,000 | 33,379,786,000 | 28,834,303,000 | 32,298,182,000 | 23,462,016,000 | 23,279,951,000 | 22,806,812,000 | 22,798,263,000 | 22,703,572,000 | 22,631,509,000 | 22,347,481,000 | 22,380,598,000 | 22,331,119,000 | 22,242,375,000 | 21,780,826,000 | 22,058,343,000 | 21,753,001,000 | 21,158,161,000 | 20,528,727,000 | 20,916,780,000 | 20,833,671,000 | 19,340,082,000 | 15,754,193,000 | 16,092,583,000 | 15,784,393,000 | 15,267,939,000 | 9,716,790,000 | |||
unrealized income on investments | -4,000 | 17,000 | -8,000 | ||||||||||||||||||||||||||||||||||
income tax expense | -1,015,000 | -392,000 | -2,649,000 | -91,000 | -38,000 | -54,000 | -3,854,000 | 9,000 | -54,000 | -21,000 | -689,000 | -709,000 | -32,000 | -325,000 | 1,137,000 | 312,000 | |||||||||||||||||||||
other comprehensive income | |||||||||||||||||||||||||||||||||||||
unrealized gain on investments | -180,000 | 267,000 | 6,000 | -49,000 | 146,000 | 20,000 | -109,000 | 62,000 | 13,000 | ||||||||||||||||||||||||||||
other comprehensive | |||||||||||||||||||||||||||||||||||||
unrealized (loss) on investments | 48,000 | -99,000 | |||||||||||||||||||||||||||||||||||
operating expense: | |||||||||||||||||||||||||||||||||||||
research and development expense | 12,696,000 | 8,640,000 | 11,923,000 | 12,124,000 | |||||||||||||||||||||||||||||||||
selling, general and administrative expense | 21,300,000 | 16,529,250 | 21,624,000 | 22,304,000 | |||||||||||||||||||||||||||||||||
other income | -2,000 | ||||||||||||||||||||||||||||||||||||
unrealized gain on marketable securities | -44,000 | -66,750 | -41,000 | -98,000 | -128,000 | -221,000 | -268,000 | 449,000 | 35,000 | -27,000 | 22,000 | 281,000 | |||||||||||||||||||||||||
net loss per ordinary share basic and diluted | -1,250 | -922.5 | -1,350 | -1,170 | -1,170 | -1,130 | -1,310 | -1,440 | 1,790 | -812.5 | -1,060 | -1,080 | 825 | 1,280 | 1,140 | 880 | 327.5 | 20 | |||||||||||||||||||
revenues | 7,485,000 | 7,966,000 | 3,461,000 | 372,000 | 18,000 | 283,000 | 364,000 | 481,000 | 327,000 | 327,000 | 7,812,000 | ||||||||||||||||||||||||||
cost of revenues | 897,000 | 652,000 | 309,000 | 48,000 | 1,055,000 | 318,000 | 430,000 | 287,000 | 287,000 | 295,000 | |||||||||||||||||||||||||||
other comprehensive income: | |||||||||||||||||||||||||||||||||||||
general and administrative expenses | 19,745,000 | 13,972,000 | 13,775,000 | 12,707,000 | 12,552,000 | 10,743,000 | 10,207,000 | 6,069,000 | 3,437,000 | 3,437,000 | 2,199,000 | 2,300,000 | |||||||||||||||||||||||||
realized loss on sale of short-term investment | 25,000 | 100,000 | |||||||||||||||||||||||||||||||||||
interest and other income (expenses) | 1,276,000 | ||||||||||||||||||||||||||||||||||||
finance income | -989,000 | ||||||||||||||||||||||||||||||||||||
loss per ordinary share basic and diluted | 1,110 | 700 | |||||||||||||||||||||||||||||||||||
interest and other expenses | -330,750 | -556,000 | -408,000 | ||||||||||||||||||||||||||||||||||
finance (expenses) income | 91,000 | ||||||||||||||||||||||||||||||||||||
income per ordinary share | |||||||||||||||||||||||||||||||||||||
basic | -740 | ||||||||||||||||||||||||||||||||||||
diluted | -740 | ||||||||||||||||||||||||||||||||||||
weighted-average number of ordinary shares outstanding | |||||||||||||||||||||||||||||||||||||
basic | 13,612,814,000 | ||||||||||||||||||||||||||||||||||||
diluted | 13,612,814,000 | ||||||||||||||||||||||||||||||||||||
finance expenses (income) | 30,500 | -5,000 | 248,000 | ||||||||||||||||||||||||||||||||||
weighted-average number of ordinary shares outstanding used in computating basic and diluted loss per ordinary share | 13,051,117,000 | 9,204,405,000 |
Balance Sheets:
Quarterly
Annual
| Unit: USD | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-08-14 | 2018-06-30 | 2018-05-15 | 2018-03-31 | 2018-03-15 | 2017-12-31 | 2017-11-14 | 2017-09-30 | 2017-08-14 | 2017-06-30 |
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assets | |||||||||||||||||||||||||||||||||||||||||
current assets: | |||||||||||||||||||||||||||||||||||||||||
cash and cash equivalents | 109,968,000 | 110,745,000 | 90,039,000 | 92,904,000 | 104,033,000 | 171,987,000 | 124,916,000 | 219,972,000 | 131,439,000 | 95,002,000 | 119,305,000 | 20,127,000 | 36,540,000 | 55,408,000 | 28,686,000 | 80,690,000 | 105,379,000 | 44,360,000 | 55,337,000 | 63,322,000 | 40,492,000 | 52,864,000 | 24,565,000 | 36,350,000 | 26,468,000 | 49,688,000 | 66,147,000 | 90,424,000 | 246,692,000 | 101,318,000 | 109,483,000 | 119,109,000 | 119,109,000 | 127,460,000 | 127,460,000 | 36,999,000 | 36,999,000 | 79,171,000 | 79,171,000 | 77,093,000 | 77,093,000 |
marketable securities | 30,306,000 | 9,711,000 | 36,994,000 | 64,050,000 | 91,857,000 | 64,698,000 | 124,659,000 | 21,106,000 | 32,606,000 | 41,966,000 | 28,114,000 | 27,174,000 | 28,514,000 | 44,556,000 | 67,225,000 | 31,048,000 | 31,065,000 | 44,779,000 | 50,872,000 | 57,710,000 | 35,417,000 | 49,154,000 | 95,058,000 | 88,773,000 | 92,623,000 | 97,389,000 | 92,046,000 | 98,739,000 | |||||||||||||
restricted cash | 1,327,000 | 1,350,000 | 1,347,000 | 1,082,000 | 1,076,000 | 1,076,000 | 1,073,000 | 825,000 | 823,000 | 821,000 | 817,000 | 816,000 | 814,000 | 813,000 | 812,000 | 811,000 | 550,000 | 1,226,000 | 1,226,000 | 1,225,000 | 1,225,000 | 1,226,000 | 1,224,000 | 1,224,000 | 1,223,000 | 523,000 | |||||||||||||||
accounts receivable | 55,412,000 | 33,082,000 | 19,703,000 | 19,649,000 | 19,638,000 | 20,302,000 | 22,802,000 | 17,415,000 | 14,158,000 | 15,443,000 | 12,847,000 | 15,505,000 | 12,493,000 | 12,704,000 | 9,429,000 | 11,595,000 | 9,499,000 | 11,717,000 | 7,784,000 | 9,512,000 | 6,301,000 | 7,047,000 | 2,810,000 | 402,000 | 112,000 | 232,000 | 232,000 | 4,000 | 4,000 | 34,000 | 34,000 | 10,000 | 10,000 | ||||||||
inventories | 20,921,000 | 16,464,000 | 8,341,000 | 7,128,000 | 7,590,000 | 9,227,000 | 7,594,000 | 7,442,000 | 7,243,000 | 5,673,000 | 5,002,000 | 4,988,000 | 5,466,000 | 4,325,000 | 4,862,000 | 5,047,000 | 4,756,000 | 4,832,000 | 3,808,000 | 3,421,000 | |||||||||||||||||||||
prepaid expenses and other current assets | 19,530,000 | 14,672,000 | 12,122,000 | 12,055,000 | 12,983,000 | 8,845,000 | 14,053,000 | 12,208,000 | 10,491,000 | 10,281,000 | 16,038,000 | 12,723,000 | 12,146,000 | 11,101,000 | 10,580,000 | 10,433,000 | 6,316,000 | 3,364,000 | 4,335,000 | 2,069,000 | 1,552,000 | 1,034,000 | 1,160,000 | 1,724,000 | 1,196,000 | 672,000 | 1,679,000 | 1,024,000 | 1,024,000 | 726,000 | 726,000 | 958,000 | 958,000 | 910,000 | 910,000 | 704,000 | 704,000 | ||||
total current assets | 237,464,000 | 186,024,000 | 168,546,000 | 196,868,000 | 237,177,000 | 276,135,000 | 295,097,000 | 278,968,000 | 196,760,000 | 169,186,000 | 182,123,000 | 81,333,000 | 95,973,000 | 128,907,000 | 121,594,000 | 139,624,000 | 160,524,000 | 114,390,000 | 125,140,000 | 140,498,000 | 93,082,000 | 115,619,000 | 129,338,000 | 129,943,000 | 121,866,000 | 148,634,000 | 159,876,000 | 191,194,000 | 248,295,000 | 102,243,000 | 111,471,000 | 120,704,000 | 120,704,000 | 128,736,000 | 128,736,000 | 74,472,000 | 74,472,000 | 80,449,000 | 80,449,000 | 78,302,000 | 78,302,000 |
non-current assets: | |||||||||||||||||||||||||||||||||||||||||
property and equipment | 616,000 | 637,000 | 695,000 | 688,000 | 627,000 | 655,000 | 608,000 | 580,000 | 566,000 | 689,000 | 823,000 | 910,000 | 1,103,000 | 1,297,000 | 1,519,000 | 1,605,000 | 1,777,000 | 1,967,000 | 1,978,000 | 2,001,000 | 2,142,000 | 2,046,000 | 1,725,000 | 1,401,000 | 991,000 | 977,000 | 893,000 | 909,000 | 929,000 | 948,000 | 992,000 | 718,000 | 718,000 | 637,000 | 637,000 | 805,000 | 805,000 | 710,000 | 710,000 | 707,000 | 707,000 |
restricted deposit | 177,000 | 177,000 | 177,000 | 177,000 | 176,000 | 176,000 | 175,000 | 175,000 | 226,000 | 225,000 | 225,000 | 224,000 | 224,000 | 223,000 | 223,000 | 223,000 | 223,000 | 223,000 | 223,000 | 223,000 | 223,000 | 223,000 | 223,000 | 223,000 | 223,000 | 223,000 | 523,000 | 307,000 | 407,000 | 253,000 | 197,000 | 197,000 | 197,000 | 197,000 | 197,000 | 198,000 | 198,000 | 197,000 | 197,000 | 97,000 | 97,000 |
right of use assets | 7,940,000 | 8,489,000 | 5,551,000 | 4,753,000 | 1,052,000 | 1,250,000 | 1,443,000 | 1,905,000 | 2,107,000 | 2,329,000 | 2,452,000 | 2,666,000 | 2,116,000 | ||||||||||||||||||||||||||||
other non-current assets | 7,493,000 | 5,161,000 | 6,759,000 | 801,000 | 371,000 | 589,000 | 370,000 | 673,000 | 1,098,000 | 2,038,000 | 2,050,000 | 2,817,000 | 3,160,000 | 2,740,000 | 2,471,000 | 1,900,000 | 1,572,000 | 1,311,000 | 1,773,000 | 1,103,000 | 66,000 | 66,000 | 55,000 | 279,000 | 264,000 | 2,423,000 | 2,557,000 | 2,777,000 | 317,000 | 14,000 | 244,000 | 244,000 | |||||||||
total assets | 253,690,000 | 200,455,000 | 185,046,000 | 208,717,000 | 247,618,000 | 285,711,000 | 301,943,000 | 281,849,000 | 200,574,000 | 178,311,000 | 193,633,000 | 95,361,000 | 112,954,000 | 135,619,000 | 128,473,000 | 146,141,000 | 165,715,000 | 119,746,000 | 134,603,000 | 153,768,000 | 97,414,000 | 122,005,000 | 139,893,000 | 161,077,000 | 166,929,000 | 202,388,000 | 226,753,000 | 238,566,000 | 252,052,000 | 103,559,000 | 112,558,000 | 121,502,000 | 121,502,000 | 129,402,000 | 129,402,000 | 75,550,000 | 75,550,000 | 81,188,000 | 81,188,000 | 79,038,000 | 79,038,000 |
liabilities and shareholders' deficit | |||||||||||||||||||||||||||||||||||||||||
current liabilities: | |||||||||||||||||||||||||||||||||||||||||
accounts payable and accrued expenses | 35,346,000 | 27,717,000 | 26,173,000 | 30,962,000 | 30,322,000 | 27,431,000 | 19,685,000 | 23,754,000 | 18,158,000 | 16,538,000 | 14,083,000 | 16,403,000 | 17,130,000 | 12,383,000 | 9,356,000 | 8,647,000 | 12,102,000 | 10,558,000 | 10,023,000 | 8,492,000 | 9,203,000 | 8,500,000 | 11,186,000 | 7,880,000 | 7,071,000 | 5,942,000 | 8,540,000 | 6,291,000 | 5,655,000 | 5,655,000 | 4,048,000 | 4,048,000 | 4,435,000 | 4,435,000 | 3,488,000 | 3,488,000 | 3,543,000 | 3,543,000 | |||
employee related accrued expenses | 9,837,000 | 13,516,000 | 11,114,000 | 11,646,000 | 6,967,000 | 10,570,000 | 9,029,000 | 6,849,000 | 4,985,000 | 10,814,000 | 8,152,000 | 6,721,000 | 4,919,000 | 8,257,000 | 6,625,000 | 6,428,000 | 6,948,000 | 4,712,000 | 9,554,000 | 7,791,000 | 5,744,000 | 4,075,000 | 6,711,000 | 5,082,000 | 3,706,000 | 3,334,000 | 4,925,000 | 2,684,000 | 2,211,000 | 2,211,000 | 1,291,000 | 1,291,000 | 1,950,000 | 1,950,000 | 1,139,000 | 1,139,000 | 1,112,000 | 1,112,000 | |||
other current liabilities | 5,452,000 | 5,185,000 | 4,957,000 | 4,940,000 | 4,711,000 | 7,948,000 | 4,073,000 | 3,620,000 | 3,197,000 | 3,860,000 | 3,553,000 | 3,641,000 | 3,185,000 | 3,276,000 | 3,018,000 | 2,965,000 | 4,009,000 | 3,330,000 | 2,268,000 | 1,941,000 | 1,735,000 | 1,859,000 | 1,335,000 | 1,476,000 | 1,632,000 | 1,585,000 | 1,126,000 | 1,067,000 | 1,001,000 | ||||||||||||
total current liabilities: | 50,635,000 | 46,418,000 | 42,244,000 | 47,548,000 | 42,000,000 | 45,949,000 | 32,787,000 | 34,223,000 | 26,340,000 | 31,212,000 | 25,788,000 | 26,765,000 | 25,234,000 | 23,916,000 | 18,999,000 | 18,040,000 | 19,091,000 | 22,380,000 | 19,806,000 | 19,056,000 | 17,005,000 | 21,436,000 | 17,618,000 | ||||||||||||||||||
non-current liabilities: | |||||||||||||||||||||||||||||||||||||||||
prepaid forward obligation | 128,228,000 | 127,276,000 | 126,067,000 | 124,833,000 | 123,336,000 | 121,387,000 | 118,526,000 | 115,880,000 | 112,947,000 | 109,722,000 | 107,276,000 | 104,507,000 | 101,912,000 | 98,923,000 | 96,192,000 | 93,461,000 | 89,782,000 | 85,713,000 | 79,927,000 | 74,802,000 | |||||||||||||||||||||
long-term debt | 189,530,000 | 122,210,000 | 122,111,000 | 122,508,000 | 122,108,000 | 121,734,000 | 121,709,000 | 97,813,000 | 97,590,000 | 98,551,000 | 98,518,000 | 98,296,000 | 97,941,000 | 97,537,000 | 71,870,000 | 71,196,000 | 70,797,000 | ||||||||||||||||||||||||
long-term lease liabilities | 5,647,000 | 6,122,000 | 6,241,000 | 3,413,000 | 2,841,000 | 1,653,000 | 212,000 | 425,000 | 637,000 | 844,000 | 1,026,000 | 1,209,000 | 1,403,000 | 1,586,000 | 1,856,000 | 1,515,000 | 398,000 | ||||||||||||||||||||||||
uncertain tax positions liability | 3,903,000 | 3,903,000 | 3,791,000 | 3,791,000 | 3,791,000 | 3,791,000 | 3,194,000 | 3,194,000 | 3,194,000 | 3,194,000 | 3,018,000 | 3,018,000 | 3,018,000 | 3,018,000 | 2,842,000 | 2,842,000 | 2,842,000 | 2,842,000 | 2,717,000 | 2,717,000 | 2,717,000 | 2,717,000 | |||||||||||||||||||
total liabilities | 377,943,000 | 305,929,000 | 300,454,000 | 302,093,000 | 294,076,000 | 294,514,000 | 276,428,000 | 251,535,000 | 240,708,000 | 243,523,000 | 235,626,000 | 233,795,000 | 229,508,000 | 224,980,000 | 191,759,000 | 187,054,000 | 182,789,000 | 111,333,000 | 103,066,000 | 97,497,000 | 20,923,000 | 25,650,000 | 19,366,000 | 18,417,000 | 16,475,000 | 22,086,000 | 15,837,000 | 13,787,000 | 12,461,000 | 13,465,000 | 8,975,000 | 7,952,000 | 7,952,000 | 5,535,000 | 5,535,000 | 7,035,000 | 7,035,000 | 4,927,000 | 4,927,000 | 4,966,000 | 4,966,000 |
commitments and contingencies | |||||||||||||||||||||||||||||||||||||||||
shareholders' deficit: | |||||||||||||||||||||||||||||||||||||||||
ordinary shares, nis 0.01 par value... | 134,000 | 133,000 | 128,000 | 126,000 | 126,000 | 115,000 | 115,000 | 112,000 | 99,000 | 89,000 | 84,000 | 64,000 | 64,000 | 63,000 | 63,000 | 62,000 | 62,000 | 61,000 | 61,000 | 61,000 | 61,000 | 60,000 | 60,000 | 60,000 | 58,000 | 57,000 | 57,000 | 57,000 | 56,000 | 44,000 | 44,000 | 43,000 | 43,000 | 42,000 | 42,000 | 37,000 | |||||
additional paid-in capital | 858,895,000 | 854,090,000 | 817,793,000 | 806,497,000 | 803,467,000 | 797,248,000 | 793,874,000 | 775,270,000 | 671,438,000 | 614,035,000 | 611,389,000 | 493,109,000 | 490,744,000 | 487,787,000 | 485,041,000 | 481,485,000 | 478,646,000 | 475,698,000 | 470,341,000 | 464,823,000 | 458,723,000 | 452,525,000 | 445,950,000 | 438,999,000 | 415,895,000 | 407,986,000 | 399,600,000 | 391,233,000 | 383,850,000 | 212,921,000 | 202,693,000 | 192,129,000 | 192,129,000 | 184,421,000 | 184,421,000 | 115,692,000 | 115,692,000 | 113,354,000 | 113,354,000 | 110,867,000 | 110,867,000 |
accumulated deficit | -983,290,000 | -959,716,000 | -933,352,000 | -900,005,000 | -850,065,000 | -806,222,000 | -768,710,000 | -745,037,000 | -711,634,000 | -679,348,000 | -653,332,000 | -631,453,000 | -607,317,000 | -577,104,000 | -548,235,000 | -522,404,000 | -495,713,000 | -467,321,000 | -438,869,000 | -408,658,000 | -382,436,000 | -356,501,000 | -325,975,000 | -297,159,000 | -265,810,000 | -228,017,000 | -189,044,000 | -166,792,000 | -144,315,000 | -122,871,000 | -99,154,000 | -78,622,000 | -78,622,000 | -60,596,000 | -60,596,000 | -47,214,000 | -47,214,000 | -37,128,000 | -37,128,000 | -36,830,000 | -36,830,000 |
accumulated other comprehensive income | 8,000 | 19,000 | 23,000 | 6,000 | 14,000 | 56,000 | 236,000 | -31,000 | 12,000 | -69,000 | -25,000 | 4,000 | 45,000 | 143,000 | 271,000 | 492,000 | 760,000 | 311,000 | 276,000 | 303,000 | 281,000 | ||||||||||||||||||||
total shareholders' deficit | -124,253,000 | -105,474,000 | -115,408,000 | -93,376,000 | -46,458,000 | -8,803,000 | -40,134,000 | -65,212,000 | -41,993,000 | -138,434,000 | -116,554,000 | ||||||||||||||||||||||||||||||
total liabilities and shareholders' deficit | 253,690,000 | 200,455,000 | 185,046,000 | 208,717,000 | 247,618,000 | 285,711,000 | 200,574,000 | 178,311,000 | 193,633,000 | 95,361,000 | 112,954,000 | ||||||||||||||||||||||||||||||
right-of-use assets | 8,456,000 | 3,134,000 | 1,671,000 | ||||||||||||||||||||||||||||||||||||||
liabilities and shareholders' equity | |||||||||||||||||||||||||||||||||||||||||
shareholders' equity | |||||||||||||||||||||||||||||||||||||||||
total shareholders' equity | 25,515,000 | 30,314,000 | -63,286,000 | -40,913,000 | -17,074,000 | 8,413,000 | 31,537,000 | 56,271,000 | 76,491,000 | 96,355,000 | |||||||||||||||||||||||||||||||
total liabilities and shareholders' equity | 301,943,000 | 281,849,000 | 128,473,000 | 146,141,000 | 165,715,000 | 119,746,000 | 134,603,000 | 153,768,000 | 97,414,000 | 122,005,000 | |||||||||||||||||||||||||||||||
accumulated other comprehensive loss | -37,000 | -134,000 | -154,000 | -45,000 | -107,000 | -155,000 | -56,000 | ||||||||||||||||||||||||||||||||||
total shareholders' (deficit) equity | -89,361,000 | ||||||||||||||||||||||||||||||||||||||||
total liabilities and shareholders' (deficit) equity | 135,619,000 | ||||||||||||||||||||||||||||||||||||||||
prepaid expense and other current assets | 9,275,000 | 7,476,000 | 6,113,000 | 5,308,000 | |||||||||||||||||||||||||||||||||||||
right of use asset | 945,000 | 1,180,000 | 1,418,000 | 1,653,000 | 1,901,000 | 2,158,000 | 2,652,000 | 3,011,000 | 3,433,000 | 3,735,000 | |||||||||||||||||||||||||||||||
accounts payable and accrued expense | 9,936,000 | 11,062,000 | 10,342,000 | ||||||||||||||||||||||||||||||||||||||
employee related accrued expense | 5,146,000 | 6,476,000 | 6,773,000 | ||||||||||||||||||||||||||||||||||||||
long-term lease liability | 277,000 | 616,000 | 922,000 | 1,201,000 | 1,497,000 | 1,748,000 | 1,994,000 | 2,268,000 | 2,604,000 | 1,749,000 | 1,943,000 | 2,184,000 | |||||||||||||||||||||||||||||
shareholders' equity: | |||||||||||||||||||||||||||||||||||||||||
inventory | 3,331,000 | 1,964,000 | 1,346,000 | 1,125,000 | 142,000 | 142,000 | 349,000 | 349,000 | 316,000 | 316,000 | 137,000 | 137,000 | 398,000 | 398,000 | |||||||||||||||||||||||||||
liabilities and shareholder's equity | |||||||||||||||||||||||||||||||||||||||||
total shareholders’ equity | 120,527,000 | 142,660,000 | 150,454,000 | 180,302,000 | 210,916,000 | 224,779,000 | 239,591,000 | 90,094,000 | 103,583,000 | 113,550,000 | 113,550,000 | 123,867,000 | 123,867,000 | 68,515,000 | 68,515,000 | 76,261,000 | 76,261,000 | 74,072,000 | 74,072,000 | ||||||||||||||||||||||
total liabilities and shareholders’ equity | 139,893,000 | 161,077,000 | 166,929,000 | 202,388,000 | 226,753,000 | 238,566,000 | 252,052,000 | 103,559,000 | 112,558,000 | 121,502,000 | 121,502,000 | 129,402,000 | 129,402,000 | 75,550,000 | 75,550,000 | 81,188,000 | 81,188,000 | 79,038,000 | 79,038,000 | ||||||||||||||||||||||
non-current assets | |||||||||||||||||||||||||||||||||||||||||
total current liabilities | 16,423,000 | 14,207,000 | 19,482,000 | 14,088,000 | 11,844,000 | 10,277,000 | 13,465,000 | 8,975,000 | 7,952,000 | 7,952,000 | 5,535,000 | 5,535,000 | 7,035,000 | 7,035,000 | 4,927,000 | 4,927,000 | 4,966,000 | 4,966,000 | |||||||||||||||||||||||
shareholders’ equity: | |||||||||||||||||||||||||||||||||||||||||
non-current liability: | |||||||||||||||||||||||||||||||||||||||||
total non-current liabilities | 1,749,000 | 1,943,000 | 2,184,000 | ||||||||||||||||||||||||||||||||||||||
short-term investments | 36,001,000 | 36,001,000 | |||||||||||||||||||||||||||||||||||||||
deferred revenues | 86,000 | 86,000 | 196,000 | 196,000 | 650,000 | 650,000 | 300,000 | 300,000 | 311,000 | 311,000 | |||||||||||||||||||||||||||||||
liabilities and shareholders’ equity | |||||||||||||||||||||||||||||||||||||||||
proceeds from exercise of warrants for preferred shares | |||||||||||||||||||||||||||||||||||||||||
warrants for preferred shares | |||||||||||||||||||||||||||||||||||||||||
ordinary shares, nis 0.01 par value: 100,000,000 and 17,600,000 shares authorized at december 31, 2017 and 2016, respectively; 13,751,390 and 2,305,743 shares issued and outstanding at december 31, 2017 and 2016, respectively. | 37,000 | ||||||||||||||||||||||||||||||||||||||||
series a and a-1 preferred shares, nis 0.01 par value: 0 and 14,400,000 shares authorized at december 31, 2017 and 2016, respectively; 0 and 5,193,427 shares issued and outstanding at december 31, 2017 and 2016, respectively. | |||||||||||||||||||||||||||||||||||||||||
non-current liabilities | |||||||||||||||||||||||||||||||||||||||||
series a and a-1 preferred shares, nis 0.01 par value: 0 and 14,400,000 shares authorized at december 31, 2017 and 2016, respectively; 0 and 5,193,427 shares issued and outstanding at december 31, 2017 and 2016, respectively | |||||||||||||||||||||||||||||||||||||||||
ordinary shares, nis 0.01 par value: 100,000,000 shares and 17,600,000 shares authorized at september 30, 2017 and december 31, 2016, respectively; 13,178,400 and 2,305,743 issued and outstanding at september 30, 2017 and december 31, 2016, respectively. | 35,000 | 35,000 | |||||||||||||||||||||||||||||||||||||||
preferred a and preferred a-1 shares, nis 0.01 par value: 14,400,000 shares authorized at december 31, 2016, 5,193,427 shares issued and outstanding at december 31, 2016. | |||||||||||||||||||||||||||||||||||||||||
ordinary shares, nis 0.01 par value: 100,000,000 shares and 17,600,000 shares authorized at june 30, 2017 and december 31, 2016, respectively; 13,009,504 and 2,305,743 issued and outstanding at june 30, 2017 and december 31, 2016, respectively. | 35,000 | 35,000 |
Cashflow Statements:
Quarterly
Annual
| Unit: USD | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-05-15 | 2018-03-31 | 2017-11-14 | 2017-09-30 | 2017-08-14 | 2017-06-30 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cash flows from operating activities | ||||||||||||||||||||||||||||||||||||||
net loss | -23,574,000 | -26,364,000 | -33,347,000 | -49,940,000 | -43,843,000 | -37,512,000 | -23,673,000 | -33,403,000 | -32,286,000 | -26,016,000 | -21,879,000 | -24,136,000 | -30,213,000 | -28,869,000 | -25,831,000 | -26,691,000 | -28,392,000 | -28,452,000 | -30,211,000 | -26,222,000 | -25,935,000 | -30,526,000 | -28,816,000 | -31,349,000 | -37,793,000 | -38,973,000 | -22,252,000 | -22,477,000 | -21,444,000 | -23,717,000 | -20,532,000 | -13,382,000 | -9,914,000 | -9,616,000 | ||||
adjustment to reconcile net loss to net cash from operating activities: | ||||||||||||||||||||||||||||||||||||||
depreciation and amortization | 75,000 | 75,000 | 80,000 | 80,000 | 72,000 | 68,000 | 68,000 | 70,000 | 123,000 | 190,000 | 186,000 | 209,000 | 217,000 | 236,000 | 239,000 | 234,000 | 215,000 | 213,000 | 217,000 | 210,000 | 191,000 | 121,000 | 117,000 | 96,000 | 82,000 | 108,000 | 65,000 | 60,000 | 63,000 | |||||||||
accrued financing on prepaid forward obligation | 1,059,000 | 1,270,000 | 1,472,000 | 2,012,000 | -1,889,000 | 6,064,000 | 3,074,000 | 3,340,000 | 2,599,000 | 2,790,000 | 2,732,000 | 3,109,000 | 2,873,000 | 2,988,000 | 2,660,000 | 4,070,000 | 4,289,000 | 6,265,000 | 6,253,000 | |||||||||||||||||||
amortization on marketable securities | 26,000 | -310,000 | -354,000 | -405,000 | -262,000 | 119,000 | 50,000 | 133,000 | 162,000 | -10,000 | 191,000 | |||||||||||||||||||||||||||
share-based compensation | 4,627,000 | 3,130,000 | 3,027,000 | 2,733,000 | 3,069,000 | 3,303,000 | 3,489,000 | 3,560,000 | 2,756,000 | 2,611,000 | 2,224,000 | 2,222,000 | 2,286,000 | 2,368,000 | 2,440,000 | 2,823,000 | 2,949,000 | 5,357,000 | 9,515,000 | 7,709,000 | 4,541,000 | 4,541,000 | 4,031,000 | 4,031,000 | 1,873,000 | 1,873,000 | ||||||||||||
amortization of discount on long-term debt | 1,974,000 | 99,000 | -397,000 | 400,000 | 374,000 | 25,000 | -592,000 | 223,000 | -961,000 | 33,000 | 222,000 | 355,000 | 404,000 | 677,000 | ||||||||||||||||||||||||
amortization of right of use assets | 577,000 | 559,000 | 516,000 | 425,000 | 198,000 | 193,000 | 228,000 | 229,000 | 222,000 | 218,000 | 214,000 | 196,000 | ||||||||||||||||||||||||||
acquisitions of ipr&d | 0 | 0 | 0 | 3,128,000 | ||||||||||||||||||||||||||||||||||
changes in operating assets and liabilities: | ||||||||||||||||||||||||||||||||||||||
inventory | -4,457,000 | -8,123,000 | -1,213,000 | 462,000 | 1,637,000 | -1,633,000 | -152,000 | -199,000 | -1,570,000 | -671,000 | -14,000 | 477,000 | -1,140,000 | 283,000 | -165,000 | -556,000 | 76,000 | -1,024,000 | -387,000 | -90,000 | -1,367,000 | -618,000 | ||||||||||||||||
accounts receivable | -22,330,000 | -13,379,000 | -54,000 | -11,000 | 664,000 | 2,500,000 | -5,387,000 | -3,257,000 | 1,285,000 | -2,596,000 | 2,658,000 | -3,012,000 | 211,000 | -3,275,000 | 2,166,000 | -2,096,000 | 2,218,000 | -3,934,000 | 1,728,000 | -3,211,000 | 746,000 | -4,237,000 | ||||||||||||||||
prepaid expenses and other current assets | -4,858,000 | -2,550,000 | -67,000 | 928,000 | -4,138,000 | 5,208,000 | -1,845,000 | -1,717,000 | -210,000 | 5,757,000 | -3,315,000 | -577,000 | -1,045,000 | -522,000 | -146,000 | -2,952,000 | 931,000 | |||||||||||||||||||||
other non-current assets | -2,332,000 | 1,598,000 | -5,958,000 | -430,000 | 218,000 | -219,000 | 303,000 | 425,000 | 940,000 | 12,000 | 767,000 | 344,000 | -421,000 | -269,000 | -556,000 | -275,000 | -169,000 | 553,000 | -547,000 | |||||||||||||||||||
accounts payable and accrued expenses | 7,629,000 | 1,544,000 | -4,789,000 | 640,000 | 2,891,000 | 7,746,000 | -4,069,000 | 5,596,000 | 1,620,000 | 2,455,000 | -2,320,000 | -727,000 | 4,747,000 | 3,027,000 | 708,000 | 535,000 | 1,261,000 | |||||||||||||||||||||
employee related accrued expenses | -3,679,000 | 2,402,000 | -532,000 | 4,679,000 | -3,603,000 | 1,541,000 | 2,180,000 | 1,864,000 | -5,829,000 | 2,662,000 | 1,431,000 | 1,802,000 | -3,338,000 | 1,632,000 | 197,000 | -4,842,000 | 1,763,000 | |||||||||||||||||||||
other current liabilities | -1,000 | -263,000 | -421,000 | 483,000 | 1,000 | 0 | -1,005,000 | 301,000 | 642,000 | -790,000 | ||||||||||||||||||||||||||||
lease liabilities | -53,000 | 1,333,000 | -628,000 | -606,000 | -738,000 | -408,000 | -184,000 | -195,000 | -247,000 | -221,000 | -262,000 | -252,000 | -252,000 | -269,000 | -282,000 | |||||||||||||||||||||||
net cash from operating activities | -45,316,000 | -38,325,000 | -42,270,000 | -39,825,000 | -42,024,000 | -13,619,000 | -27,664,000 | -23,748,000 | -31,735,000 | -12,996,000 | -17,299,000 | -20,274,000 | -25,807,000 | -21,752,000 | -17,612,000 | -24,199,000 | -23,996,000 | -20,070,000 | -18,476,000 | -18,945,000 | -27,401,000 | -21,242,000 | -25,080,000 | -23,929,000 | -35,635,000 | -26,000,000 | -12,528,000 | -14,555,000 | -17,934,000 | -10,284,000 | -9,279,000 | -8,147,000 | -9,624,000 | -9,624,000 | -3,609,000 | -3,609,000 | -6,206,000 | -6,206,000 |
capital expenditures | -54,000 | -17,000 | -87,000 | -141,000 | -44,000 | -115,000 | -96,000 | 0 | -56,000 | -100,000 | -15,000 | -23,000 | -13,000 | -153,000 | -63,000 | -25,000 | -202,000 | -194,000 | -69,000 | -287,000 | 0 | -660,000 | -287,000 | -96,000 | 0 | -49,000 | 0 | -44,000 | -24,000 | -332,000 | -132,000 | -72,000 | -72,000 | -118,000 | -118,000 | |||
free cash flows | -45,370,000 | -38,342,000 | -42,357,000 | -39,966,000 | -42,068,000 | -13,734,000 | -27,760,000 | -23,748,000 | -13,052,000 | -17,399,000 | -20,289,000 | -25,830,000 | -21,765,000 | -17,765,000 | -24,262,000 | -24,021,000 | -20,272,000 | -18,670,000 | -19,014,000 | -27,688,000 | -21,242,000 | -25,740,000 | -24,216,000 | -35,731,000 | -26,000,000 | -12,577,000 | -14,555,000 | -17,978,000 | -10,308,000 | -9,611,000 | -8,279,000 | -9,696,000 | -9,696,000 | -3,727,000 | -3,727,000 | |||
cash flows from investing activities | ||||||||||||||||||||||||||||||||||||||
purchases of marketable securities | -24,780,000 | -539,000 | -8,721,000 | -1,789,000 | -66,351,000 | -9,229,000 | -14,823,000 | -10,833,000 | 0 | -24,176,000 | 0 | -9,939,000 | ||||||||||||||||||||||||||
maturities of marketable securities | 4,146,000 | 28,273,000 | 40,206,000 | 30,336,000 | 40,432,000 | 69,965,000 | 12,140,000 | 12,082,000 | 13,518,000 | 3,535,000 | 11,334,000 | 3,735,000 | 30,469,000 | 23,121,000 | 27,669,000 | -88,000 | 13,621,000 | 9,631,000 | 18,330,000 | 10,984,000 | 15,311,000 | 49,638,000 | 13,893,000 | 38,111,000 | 22,499,000 | 38,490,000 | ||||||||||||
purchases of property and equipment | -54,000 | -17,000 | -87,000 | -141,000 | -44,000 | -115,000 | -96,000 | -56,000 | -100,000 | -15,000 | -23,000 | -13,000 | -153,000 | -63,000 | -25,000 | -202,000 | -194,000 | -69,000 | -287,000 | -660,000 | -287,000 | -96,000 | -49,000 | |||||||||||||||
net cash from investing activities | -20,688,000 | 27,717,000 | 31,398,000 | 28,406,000 | -25,963,000 | 60,621,000 | -106,750,000 | 11,998,000 | 13,518,000 | -11,344,000 | 401,000 | 3,720,000 | 6,270,000 | 23,108,000 | -35,493,000 | -151,000 | 13,596,000 | 9,125,000 | 10,660,000 | -30,740,000 | 15,024,000 | 49,465,000 | 13,234,000 | 17,514,000 | 13,025,000 | 9,296,000 | -12,659,000 | -142,186,000 | -44,000 | -26,000 | -333,000 | -183,000 | 35,829,000 | 35,829,000 | -223,000 | -223,000 | -103,000 | -103,000 |
cash flows from financing activities | ||||||||||||||||||||||||||||||||||||||
principal payments on finance leases | -321,000 | |||||||||||||||||||||||||||||||||||||
proceeds from exercise of options into ordinary shares | 179,000 | 1,343,000 | 302,000 | 297,000 | 30,000 | 71,000 | 115,000 | 40,000 | 19,000 | 143,000 | 671,000 | 378,000 | 1,117,000 | 0 | 3,000 | 54,000 | 4,000 | 89,000 | 148,000 | 210,000 | 293,000 | 321,000 | 1,126,000 | 685,000 | 1,532,000 | |||||||||||||
proceeds from issuance of long-term debt | 65,346,000 | 24,990,000 | 0 | -38,000 | 70,831,000 | |||||||||||||||||||||||||||||||||
proceeds from ordinary shares issuances, net of issuance costs | 31,831,000 | |||||||||||||||||||||||||||||||||||||
net cash from financing activities | 65,204,000 | 31,316,000 | 8,272,000 | 296,000 | 34,000 | 71,000 | 39,606,000 | 100,285,000 | 54,657,000 | 40,000 | 116,077,000 | 143,000 | 671,000 | 25,368,000 | 1,101,000 | -77,000 | 70,742,000 | -32,000 | -168,000 | 72,515,000 | 4,000 | 78,000 | 61,000 | 16,298,000 | 90,000 | 245,000 | 1,126,000 | 373,000 | 163,506,000 | 2,200,000 | -14,000 | -21,000 | 64,256,000 | 64,256,000 | 61,641,000 | 61,641,000 | 62,040,000 | 62,040,000 |
decrease in cash and cash equivalents | -800,000 | -12,373,000 | 28,301,000 | |||||||||||||||||||||||||||||||||||
cash, cash equivalents and restricted cash at beginning of period | 112,095,000 | 0 | 0 | 173,062,000 | 0 | 0 | 95,822,000 | 0 | 0 | 56,220,000 | 1,000 | -1,000 | 45,587,000 | 0 | 0 | 54,090,000 | ||||||||||||||||||||||
cash, cash equivalents and restricted cash at end of period | 111,295,000 | -2,600,000 | -11,123,000 | 105,109,000 | -94,808,000 | 88,535,000 | 132,262,000 | 99,179,000 | -16,411,000 | 37,354,000 | -52,003,000 | -24,428,000 | 105,929,000 | -7,984,000 | 22,830,000 | 41,717,000 | ||||||||||||||||||||||
supplemental disclosures of non-cash activities | ||||||||||||||||||||||||||||||||||||||
right-of-use assets obtained in exchange for new operating and finance lease liabilities | 60,000 | |||||||||||||||||||||||||||||||||||||
accretion on marketable securities | -75,000 | -160,000 | -866,000 | -774,000 | ||||||||||||||||||||||||||||||||||
amortization of right-of-use assets | ||||||||||||||||||||||||||||||||||||||
restricted deposit | 0 | 0 | -1,000 | 0 | ||||||||||||||||||||||||||||||||||
uncertain tax positions | ||||||||||||||||||||||||||||||||||||||
proceeds from issuance of long-term debt, net of issuance costs | ||||||||||||||||||||||||||||||||||||||
proceeds from pre-funded warrant issuance, net of issuance costs | 0 | 0 | 0 | |||||||||||||||||||||||||||||||||||
increase in cash and cash equivalents | 20,708,000 | -2,600,000 | -11,123,000 | -67,953,000 | 47,073,000 | -94,808,000 | 88,535,000 | 36,440,000 | -24,300,000 | 99,179,000 | -16,411,000 | -18,866,000 | 26,724,000 | -52,004,000 | -24,427,000 | 60,342,000 | -10,977,000 | -7,984,000 | 9,883,000 | -22,520,000 | -16,459,000 | -24,061,000 | -156,368,000 | 145,528,000 | -8,110,000 | -9,626,000 | -8,351,000 | 90,461,000 | 90,461,000 | 57,809,000 | 57,809,000 | 55,731,000 | 55,731,000 | |||||
cash, cash equivalents and restricted cash at beginning of year | ||||||||||||||||||||||||||||||||||||||
cash, cash equivalents and restricted cash at end of year | ||||||||||||||||||||||||||||||||||||||
right of use assets obtained in exchange for new operating lease liabilities | 3,498,000 | 1,313,000 | 2,045,000 | 27,000 | 0 | 95,000 | 0 | |||||||||||||||||||||||||||||||
proceeds from ordinary shares issuance, net of issuance costs | 4,000 | 0 | ||||||||||||||||||||||||||||||||||||
right-of-use assets obtained in exchange for new operating lease liabilities | ||||||||||||||||||||||||||||||||||||||
(accretion) on marketable securities | -1,074,000 | -298,000 | -183,000 | -412,000 | ||||||||||||||||||||||||||||||||||
proceeds from ordinary share issuance, net of issuance costs | 81,509,000 | 54,657,000 | ||||||||||||||||||||||||||||||||||||
inventory obsolescence | 255,000 | 350,000 | ||||||||||||||||||||||||||||||||||||
proceeds from pre-funded warrant issuance, net of 1,654 of issuance costs | 0 | |||||||||||||||||||||||||||||||||||||
proceeds from ordinary share issuance, net of 2,288 of issuance costs | 0 | |||||||||||||||||||||||||||||||||||||
issuance cost related to at-the-market issuances | 0 | -16,000 | -55,000 | -89,000 | -17,000 | -116,000 | -11,000 | |||||||||||||||||||||||||||||||
non-cash issuance cost | 3,000 | 312,000 | ||||||||||||||||||||||||||||||||||||
sales of marketable securities | 0 | |||||||||||||||||||||||||||||||||||||
proceeds from prepaid forward arrangement | -15,000 | -55,000 | ||||||||||||||||||||||||||||||||||||
interest expense on long-term debt | 121,000 | 282,000 | ||||||||||||||||||||||||||||||||||||
non-cash new lease liabilities | 1,413,000 | 6,000 | 0 | -16,000 | -20,000 | 22,000 | -43,000 | 72,000 | ||||||||||||||||||||||||||||||
amortization of right of use asset | 241,000 | 238,000 | 235,000 | 232,000 | 237,000 | 494,000 | 381,000 | 379,000 | 374,000 | |||||||||||||||||||||||||||||
lease liability | -286,000 | -262,000 | -252,000 | -400,000 | -384,000 | -409,000 | -387,000 | -361,000 | -246,000 | -201,000 | -173,000 | |||||||||||||||||||||||||||
prepaid expense and other current assets | -1,800,000 | -1,362,000 | -805,000 | |||||||||||||||||||||||||||||||||||
accounts payable and accrued expense | -2,169,000 | 966,000 | 713,000 | |||||||||||||||||||||||||||||||||||
employee related accrued expense | -1,801,000 | 472,000 | -297,000 | |||||||||||||||||||||||||||||||||||
purchase of marketable securities | -1,000 | 1,000 | -20,310,000 | -9,378,000 | -28,834,000 | |||||||||||||||||||||||||||||||||
issuances of ordinary shares, net of issuance expenses | ||||||||||||||||||||||||||||||||||||||
purchase of property and equipment | -44,000 | -24,000 | -332,000 | -132,000 | -72,000 | -72,000 | -118,000 | -118,000 | -98,000 | -98,000 | ||||||||||||||||||||||||||||
accrued issuance cost | ||||||||||||||||||||||||||||||||||||||
new lease liabilities | ||||||||||||||||||||||||||||||||||||||
issuances of ordinary shares, net of issuance expense | ||||||||||||||||||||||||||||||||||||||
exercise of options | -513,000 | 515,000 | ||||||||||||||||||||||||||||||||||||
stock-based compensation | 6,046,000 | 6,195,000 | 6,526,000 | 6,763,000 | 7,119,000 | 7,617,000 | 8,065,000 | 7,243,000 | 7,212,000 | 7,447,000 | ||||||||||||||||||||||||||||
non-cash purchases of property and equipment | ||||||||||||||||||||||||||||||||||||||
current tax payable | ||||||||||||||||||||||||||||||||||||||
change in restricted deposit | -168,000 | 0 | -2,000 | -1,000 | -105,000 | -105,000 | -5,000 | -5,000 | ||||||||||||||||||||||||||||||
issuance of ordinary shares, net of issuance expenses | 0 | -32,000 | 0 | 0 | 60,926,000 | 60,926,000 | 61,654,000 | 61,654,000 | ||||||||||||||||||||||||||||||
issuance cost | ||||||||||||||||||||||||||||||||||||||
cash flows from operating activities: | ||||||||||||||||||||||||||||||||||||||
amortization/accretion on marketable securities | 152,000 | 136,000 | 98,000 | -75,000 | -330,000 | |||||||||||||||||||||||||||||||||
cash flows from investing activities: | ||||||||||||||||||||||||||||||||||||||
cash flows from financing activities: | ||||||||||||||||||||||||||||||||||||||
cash, cash equivalents and restricted cash at beginning of the period | 0 | 0 | 50,211,000 | |||||||||||||||||||||||||||||||||||
cash, cash equivalents and restricted cash at end of the period | -11,785,000 | 9,883,000 | 27,691,000 | |||||||||||||||||||||||||||||||||||
supplemental disclosures of non-cash activities: | ||||||||||||||||||||||||||||||||||||||
increase in inventory | -33,000 | -33,000 | -293,000 | -293,000 | ||||||||||||||||||||||||||||||||||
increase in accounts receivable | -4,000 | |||||||||||||||||||||||||||||||||||||
increase in prepaid expenses and other current assets | -517,000 | -518,000 | ||||||||||||||||||||||||||||||||||||
decrease in accounts payable and accrued expenses | 452,000 | -2,498,000 | -2,440,000 | |||||||||||||||||||||||||||||||||||
decrease in employee related accrued expenses | 1,669,000 | -2,636,000 | -1,591,000 | -659,000 | -659,000 | |||||||||||||||||||||||||||||||||
supplemental disclosures of non-cash investing and financing activities: | ||||||||||||||||||||||||||||||||||||||
non-cash purchase of property and equipment | ||||||||||||||||||||||||||||||||||||||
issuance cost for shelf filing | -203,000 | |||||||||||||||||||||||||||||||||||||
fair value adjustment of warrants for preferred shares | 168,000 | 168,000 | 168,000 | 168,000 | ||||||||||||||||||||||||||||||||||
realized loss on sale of short-term investment | 0 | 0 | 0 | 100,000 | 100,000 | |||||||||||||||||||||||||||||||||
change in lease liability | ||||||||||||||||||||||||||||||||||||||
decrease in inventory | 0 | 142,000 | -32,000 | |||||||||||||||||||||||||||||||||||
decrease in accounts receivable | 120,000 | -4,000 | 49,000 | 73,000 | 73,000 | |||||||||||||||||||||||||||||||||
decrease in prepaid expenses and other current assets | 126,000 | -41,000 | -11,000 | 232,000 | -514,000 | -308,000 | ||||||||||||||||||||||||||||||||
increase in accounts payable and accrued expenses | 3,118,000 | 809,000 | 2,147,000 | 636,000 | 1,628,000 | -206,000 | -206,000 | 1,704,000 | 1,704,000 | 1,031,000 | 1,031,000 | |||||||||||||||||||||||||||
increase in deferred revenues | 0 | -86,000 | -110,000 | -454,000 | -454,000 | 300,000 | 300,000 | |||||||||||||||||||||||||||||||
increase in employee related accrued expenses | 1,629,000 | 1,376,000 | 2,241,000 | 473,000 | 452,000 | 452,000 | 425,000 | 425,000 | ||||||||||||||||||||||||||||||
sale of short-term investments | ||||||||||||||||||||||||||||||||||||||
proceeds from exercise of warrants for preferred shares | ||||||||||||||||||||||||||||||||||||||
issuance cost for secondary offering | ||||||||||||||||||||||||||||||||||||||
cash, cash equivalents and restricted cash at beginning of the year | 0 | 0 | ||||||||||||||||||||||||||||||||||||
cash, cash equivalents and restricted cash at end of the year | -16,459,000 | -24,061,000 | -156,368,000 | 247,099,000 | ||||||||||||||||||||||||||||||||||
exercise of warrants to preferred shares | ||||||||||||||||||||||||||||||||||||||
exchange rate differences | ||||||||||||||||||||||||||||||||||||||
right of use asset | 245,000 | 246,000 | 245,000 | |||||||||||||||||||||||||||||||||||
decrease in deferred revenues | ||||||||||||||||||||||||||||||||||||||
sale of short-term investment | 0 | 0 | 35,901,000 | 35,901,000 | ||||||||||||||||||||||||||||||||||
short-term investments | ||||||||||||||||||||||||||||||||||||||
issuance of ordinary shares, net of issurance expenses | 161,974,000 | |||||||||||||||||||||||||||||||||||||
cash, cash equivalents and restriced cash at beginning of the year | 101,571,000 | |||||||||||||||||||||||||||||||||||||
payment of deferred equity offering cost | ||||||||||||||||||||||||||||||||||||||
adjustments required to reconcile net loss to net cash from operating activities: | ||||||||||||||||||||||||||||||||||||||
depreciation and disposals | 58,000 | 51,000 | 240,000 | 240,000 | ||||||||||||||||||||||||||||||||||
exchange rates differences | 0 | 0 | 1,000 | 1,000 | -2,000 | -2,000 | -2,000 | -2,000 | ||||||||||||||||||||||||||||||
issuance of ordinary shares in public offering, net of issuance expenses | -14,000 | -21,000 | 64,256,000 | 64,256,000 | ||||||||||||||||||||||||||||||||||
proceeds from exercise of warrants to preferred shares | 382,000 | 382,000 | 382,000 | 382,000 | ||||||||||||||||||||||||||||||||||
balance of cash and cash equivalents at beginning of the year | 0 | 0 | 36,999,000 | 36,999,000 | ||||||||||||||||||||||||||||||||||
balance of cash and cash equivalents at end of the year | -9,626,000 | -8,351,000 | 127,460,000 | 127,460,000 | ||||||||||||||||||||||||||||||||||
exercise of warrants into preferred shares | 4,732,000 | 4,732,000 | 4,732,000 | 4,732,000 | ||||||||||||||||||||||||||||||||||
net income | -13,382,000 | -9,914,000 | -9,616,000 | |||||||||||||||||||||||||||||||||||
adjustments required to reconcile net income to net cash from operating activities: | ||||||||||||||||||||||||||||||||||||||
decrease (increase) in inventory | -32,000 | |||||||||||||||||||||||||||||||||||||
non cash issuance cost | 21,000 | 21,000 | 728,000 | 728,000 | ||||||||||||||||||||||||||||||||||
decrease (increase) in prepaid expenses and other current assets | 232,000 | -514,000 | -308,000 | |||||||||||||||||||||||||||||||||||
depreciation | 149,000 | 149,000 | 132,000 | 132,000 | ||||||||||||||||||||||||||||||||||
in process r&d | ||||||||||||||||||||||||||||||||||||||
share based compensation | ||||||||||||||||||||||||||||||||||||||
changes in operating asset and liabilities: | ||||||||||||||||||||||||||||||||||||||
proceeds from issuance of preferred shares from 2014 share purchase agreement net of issuance cost | ||||||||||||||||||||||||||||||||||||||
purchase of ip r&d in consideration for preferred a shares | ||||||||||||||||||||||||||||||||||||||
exercise of options into ordinary shares | 333,000 | 333,000 | 4,000 | 4,000 | ||||||||||||||||||||||||||||||||||
balance of cash and cash equivalents at beginning of the period | 21,362,000 | 21,362,000 | 21,362,000 | 21,362,000 | ||||||||||||||||||||||||||||||||||
balance of cash and cash equivalents at end of the period | 79,171,000 | 79,171,000 | 77,093,000 | 77,093,000 | ||||||||||||||||||||||||||||||||||
decrease (increase) in accounts receivable | 49,000 | |||||||||||||||||||||||||||||||||||||
deferred revenues | 311,000 | 311,000 | ||||||||||||||||||||||||||||||||||||
non cash purchase of property and equipment |
