7Baggers

Insmed Quarterly Balance Sheets Chart

Quarterly
 | 
Annual
 
 Goodwill  
 Account Receivables  
 Cash and Cash Eq  
 Account Payables  
 Inventory  
20200930 20201231 20210331 20210630 20210930 20211231 20220331 20220630 20220930 20221231 20230331 20230630 20230930 20231231 20240331 20240630 20240930 20241231 20250331 20250630 00.180.370.550.730.921.11.28Billion

Insmed Quarterly Balance Sheets Table

Quarterly
 | 
Annual
 
Unit: USD2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-09-30 2016-06-30 2016-03-31 2015-09-30 2015-06-30 2015-03-31 2014-09-30 2014-06-30 2014-03-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31 2010-12-31 2010-09-30 2010-06-30 2010-03-31 2009-12-31 2009-09-30 2009-06-30 2009-03-31 2008-12-31 2008-09-30 2008-06-30 2008-03-31 2007-12-31 2007-09-30 2007-06-30 2007-03-31 2006-12-31 2006-09-30 2006-06-30 2006-03-31 2005-12-31 2005-09-30 2005-06-30 2005-03-31 2004-12-31 2004-09-30 2004-06-30 2004-03-31 2003-12-31 2003-09-30 2003-06-30 2003-03-31 2002-12-31 2002-09-30 2002-06-30 2002-03-31 
                                                                                            
  assets                                                                                          
  current assets:                                                                                          
  cash and cash equivalents1,284,324,000 403,247,000 555,030,000 461,451,000 1,246,799,000 595,729,000 482,374,000 487,113,000 612,882,000 968,907,000 1,074,036,000 414,633,000 416,078,000 515,704,000 716,782,000 846,556,000 928,327,000 409,751,000 532,756,000 588,753,000 641,911,000 428,942,000 487,429,000 535,632,000 601,260,000 420,231,000 495,072,000 567,574,000 634,329,000 686,581,000 381,165,000 430,678,000 91,064,000 125,839,000 200,518,000 223,109,000 252,872,000 310,969,000 335,027,000 134,554,000 167,311,000 82,697,000 101,251,000 128,025,000 74,588,000 79,434,000 90,782,000 44,989,000 28,575,000 22,043,000 14,848,000 10,449,000 9,839,000 22,100,000 10,743,000 9,687,000 11,316,000 19,364,000 12,740,000 26,838,000        18,913,000 22,259,000 12,036,000 24,112,000 34,989,000 48,356,000 59,207,000 18,835,000 20,676,000 28,455,000 35,771,000 9,222,000 7,509,000 14,055,000 24,907,000 29,526,000 32,189,000 22,008,000 25,116,000 27,337,000 31,179,000 36,265,000 42,365,000 
  marketable securities572,441,000 796,204,000 878,796,000 1,006,457,000   298,073,000 298,838,000 304,886,000 29,774,000 74,244,000 98,662,000 138,790,000 119,415,000 50,043,000                                                                            
  accounts receivable55,033,000 47,746,000 52,012,000 42,317,000 40,300,000 37,162,000 41,189,000 35,579,000 30,947,000 30,523,000 29,713,000 27,401,000 29,481,000 25,722,000 24,351,000 19,317,000 18,417,000 17,628,000 16,562,000 15,196,000 15,173,000 17,154,000 19,232,000 15,346,000 11,638,000 9,347,000 5,515,000                        757,000 440,000 303,000 169,000 471,000 178,000 190,000 189,000 245,000 319,000 211,000 114,000 122,000 72,000 50,000 327,000 250,000 25,000  111,000 241,000 250,000 105,000                  
  inventory107,605,000 100,713,000 98,578,000 98,470,000 90,063,000 82,957,000 83,248,000 77,923,000 77,349,000 71,317,000 69,922,000 66,276,000 67,017,000 64,145,000 67,009,000 67,453,000 60,385,000 52,060,000 49,592,000 43,483,000 35,473,000 30,645,000 28,313,000 23,313,000 20,160,000 12,682,000 7,032,000                                                                
  prepaid expenses and other current assets62,177,000 54,782,000 37,245,000 41,150,000 41,022,000 42,874,000 24,179,000 27,123,000 26,360,000 28,542,000 25,468,000 25,193,000 23,360,000 31,154,000 28,898,000 25,655,000 31,066,000 21,565,000 23,982,000 19,717,000 14,755,000 15,769,000 20,220,000 21,313,000 15,856,000 12,372,000 11,327,000 9,921,000 10,929,000 9,832,000 8,279,000 6,802,000 5,470,000 5,785,000 5,778,000 6,201,000 5,618,000 8,289,000 7,062,000 5,689,000 3,532,000 4,015,000 4,958,000 1,720,000 1,783,000 1,418,000 643,000 605,000 715,000 178,000 370,000                                        
  total current assets2,081,580,000 1,402,692,000 1,621,661,000 1,649,845,000 1,418,184,000 758,722,000 929,063,000 926,576,000 1,052,424,000 1,129,063,000 1,273,383,000 632,165,000 674,726,000 756,140,000 837,040,000 958,981,000 1,038,195,000 501,004,000 622,892,000 667,149,000 707,312,000 492,510,000 555,194,000 595,604,000 648,914,000 454,632,000 518,946,000 577,495,000 645,258,000 696,413,000 389,444,000 437,480,000 96,534,000 131,624,000 206,296,000 229,310,000 258,490,000 319,258,000 342,089,000 140,243,000 170,843,000 86,712,000 106,209,000 129,745,000 78,566,000 83,025,000 93,578,000 90,353,000 73,850,000 70,960,000 77,399,000 83,983,000 92,619,000 103,062,000 108,797,000 124,893,000 125,319,000 124,805,000 124,608,000 122,537,000 123,202,000 127,684,000 2,593,000 5,961,000 9,690,000 12,467,000 16,973,000 19,669,000 22,963,000 12,675,000 25,423,000 37,484,000 50,733,000 59,525,000 19,203,000 21,093,000 28,930,000 36,156,000 9,681,000 8,274,000 15,526,000 25,291,000 29,751,000 32,534,000 22,474,000 25,243,000 28,151,000 33,772,000 38,981,000 46,199,000 
  fixed assets89,995,000 88,358,000 80,052,000 75,265,000 72,777,000 68,660,000 65,384,000 64,630,000 62,113,000 59,556,000 56,491,000 53,684,000 53,946,000 52,676,000 52,955,000 53,199,000 53,784,000 52,684,000 53,953,000 55,314,000 56,826,000 58,638,000 60,180,000 52,991,000 38,913,000 27,933,000 22,636,000 19,526,000 17,881,000 15,816,000 12,432,000 8,975,000 9,234,000 9,807,000 10,274,000 9,793,000 8,899,000 8,052,000 7,989,000 7,292,000 5,982,000 4,778,000 1,977,000 1,904,000 1,855,000 1,681,000 1,666,000 1,647,000 1,758,000 1,867,000 1,937,000 1,424,000 1,016,000 1,042,000 1,102,000                                    
  finance lease right-of-use assets16,917,000 17,595,000 18,273,000 18,951,000 19,629,000 20,307,000 20,985,000 21,663,000 22,341,000 23,019,000 23,697,000 16,697,000 17,178,000 17,814,000 9,256,000 9,525,000 9,795,000 10,064,000 10,334,000 10,603,000 14,536,000 14,896,000 15,256,000                                                                    
  operating lease right-of-use assets10,315,000 10,832,000 17,257,000 16,030,000 16,406,000 17,157,000 18,017,000 18,441,000 16,476,000 21,154,000 21,894,000 22,430,000 24,047,000 31,277,000 33,305,000 31,283,000 32,037,000 34,279,000 32,946,000 32,505,000 31,901,000 36,137,000 37,673,000 39,949,000 42,316,000                                                                  
  intangibles56,126,000 57,389,000 58,652,000 59,915,000 61,178,000 62,441,000 63,704,000 64,967,000 66,230,000 67,493,000 68,756,000 70,020,000 71,283,000 72,546,000 73,809,000 75,071,000 46,735,000 47,998,000 49,261,000 49,937,000 51,185,000 52,433,000 53,682,000 54,930,000 56,179,000 57,427,000 58,675,000                                                                
  goodwill136,110,000 136,110,000 136,110,000 136,110,000 136,110,000 136,110,000 136,110,000 136,110,000 136,110,000 136,110,000 136,110,000 136,110,000 136,110,000 136,110,000 136,110,000 136,110,000                                     6,290,000 6,290,000 6,290,000                                 15,385,000 15,385,000 15,385,000 
  other assets88,814,000 89,759,000 93,226,000 96,856,000 85,834,000 95,698,000 96,574,000 92,486,000 83,445,000 81,322,000 76,104,000 63,711,000 66,300,000 57,201,000 50,990,000 47,602,000 49,237,000 46,362,000 26,769,000 25,207,000 23,605,000 21,911,000 20,314,000 19,643,000 16,461,000 11,314,000 4,299,000 4,551,000 2,905,000 2,724,000 1,971,000 1,551,000 1,672,000 1,028,000 1,874,000 2,374,000 2,117,000 231,000 231,000 417,000 418,000 420,000 234,000 101,000 104,000 110,000 117,000                                            
  total assets2,479,857,000 1,802,735,000 2,025,231,000 2,052,972,000 1,810,118,000 1,159,095,000 1,329,837,000 1,324,873,000 1,439,139,000 1,517,717,000 1,656,435,000 994,817,000 1,053,354,000 1,153,315,000 1,243,508,000 1,311,771,000 1,229,783,000 692,391,000 796,155,000 840,715,000 885,365,000 676,525,000 742,299,000 763,117,000 802,783,000 595,915,000 604,556,000 661,513,000 724,244,000 773,153,000 462,047,000 506,206,000 165,640,000 200,659,000 276,644,000 299,677,000 327,706,000 385,741,000 408,509,000 206,152,000 235,443,000 150,110,000 166,620,000 189,950,000 138,725,000 143,016,000 153,561,000 152,457,000 136,052,000 133,253,000 139,833,000 146,069,000 180,288,000 190,470,000 196,265,000 126,978,000 127,404,000 126,890,000 126,695,000 124,629,000 125,300,000 129,820,000 4,758,000 8,148,000 11,956,000 14,812,000 19,500,000 22,582,000 25,923,000 15,708,000 28,348,000 45,081,000 56,854,000 62,640,000 22,870,000 25,741,000 33,736,000 41,125,000 13,011,000 11,607,000 18,860,000 25,338,000 29,812,000 32,610,000 22,573,000 25,370,000 28,308,000 49,345,000 55,306,000 62,638,000 
  liabilities and shareholders’ equity                                                                                          
  current liabilities:                                                                                          
  accounts payable and accrued liabilities305,019,000 232,674,000 285,209,000 248,684,000 290,844,000 189,362,000 214,987,000 187,783,000 197,653,000 179,005,000 182,117,000 131,861,000                                                                               
  finance lease liabilities3,149,000 3,054,000 2,961,000 2,871,000 2,782,000 2,695,000 2,610,000 2,527,000 2,445,000 2,158,000 1,217,000 337,000 212,000 125,000 609,000 1,198,000 1,158,000 1,119,000 1,081,000 582,000 1,305,000 1,263,000 1,221,000                                                                    
  operating lease liabilities3,513,000 3,505,000 9,358,000 7,633,000 6,077,000 4,609,000 8,032,000 6,418,000 4,159,000 6,821,000 6,909,000 5,456,000 5,037,000 9,625,000 9,527,000 5,952,000 5,925,000 6,418,000 11,475,000 9,741,000 7,499,000 10,367,000 11,040,000                                                                    
  total current liabilities311,681,000 239,233,000 297,528,000 259,188,000 524,151,000 420,860,000 225,629,000 196,728,000 204,257,000 187,984,000 190,243,000 137,654,000 113,816,000 125,249,000 135,166,000 112,501,000 99,656,000 81,397,000 118,807,000 83,902,000 78,754,000 71,532,000 85,240,000 85,392,000 86,030,000 94,252,000 79,732,000 57,419,000 45,642,000 34,806,000 44,656,000 28,766,000 26,272,000 23,271,000 23,458,000 32,320,000 25,543,000 46,698,000 43,067,000 41,125,000 21,278,000 21,818,000 19,998,000 19,822,000 18,101,000 20,272,000 15,747,000 6,545,000 6,486,000 4,136,000 4,477,000 3,682,000 3,492,000 4,463,000 3,339,000    2,781,000 3,584,000 4,616,000 13,384,000 4,877,000 4,377,000 5,698,000 3,870,000 3,682,000 3,828,000 3,150,000 7,010,000 9,681,000 6,226,000 6,076,000 3,405,000 4,870,000 4,019,000 3,938,000 4,147,000 5,048,000 6,030,000 5,763,000 3,307,000 2,946,000 3,221,000 3,664,000 3,213,000 3,892,000 6,465,000 7,089,000 7,413,000 
  debt, long-term538,508,000 1,105,068,000 1,103,382,000 954,831,000 946,825,000 939,081,000 1,155,313,000 1,147,519,000 1,139,805,000 1,132,188,000 1,125,250,000 784,799,000 783,977,000 783,156,000 566,588,000 557,604,000 548,745,000 361,575,000 356,318,000 351,127,000 346,001,000 340,939,000 335,940,000 331,003,000 326,128,000 321,313,000 316,558,000    55,567,000 55,388,000 55,194,000 54,993,000 34,681,000 16,136,000 19,114,000    14,713,000 16,494,000 14,569,000 12,538,000 14,894,000 14,511,000 16,221,000 8,503,000 8,965,000                                          
  royalty financing agreement163,534,000 162,508,000 161,067,000 160,049,000 158,377,000 156,967,000 155,034,000 153,430,000 152,020,000 150,173,000 148,015,000                                                                                
  contingent consideration180,500,000 159,900,000 144,200,000 157,600,000 101,500,000 63,700,000 84,600,000 69,900,000 46,400,000 38,600,000 51,100,000 51,800,000 55,600,000 66,120,000 75,668,000 76,490,000                                                                           
  finance lease liabilities, long-term22,439,000 23,266,000 24,064,000 24,841,000 25,588,000 26,320,000 27,026,000 27,712,000 28,370,000 29,015,000 29,636,000 22,679,000 23,135,000 23,509,000 14,103,000 13,805,000 14,114,000 14,417,000 14,713,000 15,003,000 18,855,000 19,196,000 19,529,000                                                                    
  operating lease liabilities, long-term7,899,000 8,480,000 9,112,000 9,692,000 11,666,000 13,809,000 11,013,000 13,023,000 12,871,000 14,534,000 14,853,000 16,504,000 18,201,000 19,875,000 21,441,000 22,647,000 23,409,000 24,068,000 21,255,000 23,198,000 25,099,000 27,197,000 29,308,000                                                                    
  other long-term liabilities5,561,000 5,121,000 499,000 3,356,000 3,193,000 3,166,000 3,145,000 5,918,000 11,161,000 9,876,000 9,387,000 11,340,000 14,384,000 15,526,000 20,074,000 23,882,000 12,806,000 9,298,000 9,178,000 10,424,000 11,338,000 10,960,000 10,608,000 11,264,000 522,000 504,000  826,000 805,000 785,000 765,000 747,000 729,000 711,000 676,000 660,000 586,000 44,000 102,000 162,000                                                   
  total liabilities1,230,122,000 1,703,576,000 1,739,852,000 1,569,557,000 1,771,300,000 1,623,903,000 1,661,760,000 1,614,230,000 1,594,884,000 1,562,370,000 1,568,484,000 1,024,776,000 1,009,113,000 1,033,435,000 833,040,000 806,929,000 698,730,000 490,755,000 520,271,000 483,654,000 480,047,000 469,824,000 480,625,000 459,076,000 446,210,000 451,778,000 396,290,000 370,106,000 353,603,000 338,297,000 100,988,000 84,901,000 82,195,000 78,975,000 58,815,000 49,116,000 45,243,000 46,742,000 43,169,000 41,287,000 36,176,000 38,562,000 34,882,000 32,825,000 33,541,000 35,411,000 32,679,000 15,845,000 16,336,000 5,119,000 5,566,000 3,727,000 3,550,000 4,666,000 3,422,000 2,292,000 3,018,000 2,463,000 2,781,000 3,584,000 4,616,000 13,384,000 7,581,000 7,414,000 9,261,000 7,822,000 8,012,000 8,158,000 7,645,000 12,017,000 14,468,000 11,328,000 10,953,000 8,061,000 12,341,000 19,453,000 24,618,000 23,576,000 5,776,000 6,700,000 6,394,000 3,877,000 3,592,000 3,959,000 4,486,000 4,120,000  7,417,000   
  shareholders’ equity:                                                                                          
  common stock2,111,000 1,819,000 1,794,000 1,788,000 1,667,000 1,486,000 1,480,000 1,430,000 1,428,000 1,364,000 1,357,000 1,217,000 1,199,000 1,193,000 1,187,000 1,184,000 1,152,000 1,033,000 1,028,000 1,018,000 1,014,000 899,000 897,000 893,000 892,000 776,000 773,000 771,000 770,000 766,000 766,000 766,000 624,000 621,000 619,000 619,000 619,000 618,000 617,000 500,000 496,000 393,000 393,000 391,000 320,000 316,000                                 449,000 384,000 384,000 384,000 384,000 384,000 332,000 332,000 332,000 331,000 331,000 330,000 
  additional paid-in capital6,184,078,000 4,714,742,000 4,645,791,000 4,605,449,000 3,943,826,000 3,138,578,000 3,113,487,000 2,971,375,000 2,945,229,000 2,809,242,000 2,782,416,000 2,506,665,000 2,449,281,000 2,428,582,000 2,673,556,000 2,655,823,000 2,569,028,000 2,122,743,000 2,105,252,000 2,084,305,000 2,069,119,000 1,808,712,000 1,797,286,000 1,786,667,000 1,778,517,000 1,499,646,000 1,489,664,000 1,481,205,000 1,472,699,000 1,460,460,000 1,318,181,000 1,313,006,000 930,185,000 923,760,000 914,049,000 909,004,000 904,342,000 896,099,000 891,479,000 662,514,000 651,904,000 540,298,000 537,264,000 532,141,000 462,944,000 455,725,000 455,325,000 455,560,000 429,545,000 428,237,000 427,743,000 427,234,000 426,795,000 426,146,000 423,877,000 350,458,000 350,372,000 350,308,000 350,243,000 350,125,000 349,622,000 343,817,000 342,378,000 341,973,000 341,771,000  341,270,000 340,773,000 340,675,000 323,728,000 323,664,000 322,120,000 321,895,000 321,663,000                 
  accumulated deficit-4,938,186,000 -4,616,500,000 -4,359,917,000 -4,124,369,000 -3,903,845,000 -3,603,236,000 -3,446,145,000 -3,260,084,000 -3,101,151,000 -2,856,342,000 -2,696,578,000 -2,536,455,000 -2,405,310,000 -2,309,665,000 -2,265,243,000 -2,152,265,000 -2,039,551,000 -1,922,230,000 -1,830,589,000 -1,728,376,000 -1,664,717,000 -1,602,863,000 -1,536,499,000 -1,483,511,000 -1,422,829,000 -1,356,315,000 -1,282,162,000 -1,190,589,000 -1,102,846,000 -1,026,409,000 -957,885,000 -892,501,000               -335,548,000 -320,095,000 -310,714,000 -301,018,000 -294,174,000 -286,011,000 -251,422,000 -241,404,000 -234,510,000 -228,666,000 -228,336,000 -227,958,000 -228,076,000 -230,382,000 -230,232,000 -228,631,000 -346,426,000 -342,462,000 -340,299,000  -330,759,000 -327,465,000 -323,551,000 -321,050,000 -310,797,000 -289,369,000 -276,996,000 -268,085,000 -254,658,000 -241,773,000 -228,017,000 -219,493,000 -213,729,000 -207,892,000 -200,296,000 -191,285,000 -186,526,000 -184,075,000 -181,677,000 -178,437,000 -176,228,000 -157,731,000 -153,025,000 -145,918,000 
  accumulated other comprehensive gain1,732,000                                                                                          
  total shareholders’ equity1,249,735,000 99,159,000  483,415,000 38,818,000        44,241,000 119,880,000  504,842,000 531,053,000 201,636,000  357,061,000 405,318,000 206,701,000  304,041,000 356,573,000 144,137,000  291,407,000 370,641,000 434,856,000  421,305,000 83,445,000 121,684,000 217,829,000 250,561,000 282,463,000 338,999,000 365,340,000 164,865,000 199,267,000 111,548,000 131,738,000 157,125,000 105,184,000 107,605,000                                             
  total liabilities and shareholders’ equity2,479,857,000 1,802,735,000  2,052,972,000 1,810,118,000   1,324,873,000 1,439,139,000 1,517,717,000  994,817,000 1,053,354,000 1,153,315,000  1,311,771,000 1,229,783,000 692,391,000  840,715,000 885,365,000 676,525,000  763,117,000 802,783,000 595,915,000  661,513,000 724,244,000 773,153,000  506,206,000 165,640,000 200,659,000 276,644,000 299,677,000 327,706,000 385,741,000 408,509,000 206,152,000 235,443,000 150,110,000 166,620,000 189,950,000 138,725,000 143,016,000                          45,081,000                   
  accumulated other comprehensive loss -902,000 -2,289,000  -2,830,000 -1,636,000               -98,000 -47,000 -10,000 -8,000 -7,000  -9,000    -3,000                                                            
  liabilities and shareholders' equity                                                                                          
  shareholders' equity:                                                                                          
  total shareholders' equity  285,379,000        87,951,000    410,468,000    275,884,000    261,674,000    208,266,000    361,059,000                                                            
  total liabilities and shareholders' equity  2,025,231,000    1,329,837,000    1,656,435,000    1,243,508,000    796,155,000    742,299,000    604,556,000    462,047,000                                                            
  accumulated other comprehensive income   547,000   -745,000 -2,078,000 -1,251,000 1,083,000 756,000 -1,386,000 -929,000 -230,000 968,000 100,000 424,000 90,000 193,000 114,000      30,000  20,000 18,000 39,000  34,000    12,000                                                       
  current portion of long-term debt    224,448,000 224,194,000                              8,689,000 5,674,000 25,256,000 25,123,000                                                    
  total shareholders’ deficit     -464,808,000                                                                                     
  total liabilities and shareholders’ deficit     1,159,095,000                                                                                     
  total shareholders' (deficit) equity      -331,923,000                                                                                    
  total shareholders’ (deficit) equity       -289,357,000 -155,745,000 -44,653,000  -29,959,000                                                                               
  marketable securities, non-current            9,764,000                                                                              
  accounts payable            31,144,000 48,571,000 35,784,000 23,531,000 31,081,000 22,422,000 42,853,000 22,147,000 25,005,000 18,188,000 13,184,000 20,415,000 17,031,000 30,223,000 17,741,000 16,579,000 15,966,000 13,176,000 14,671,000 9,348,000 11,030,000 8,454,000 8,283,000 9,402,000 8,688,000 10,857,000 8,681,000 7,860,000 8,867,000 11,407,000 9,818,000 4,661,000 7,865,000 8,184,000 7,060,000 2,985,000 3,198,000 2,879,000 2,334,000 1,504,000 1,921,000 3,082,000 1,450,000 431,000 912,000 433,000 312,000 581,000 711,000 2,667,000 1,277,000 1,117,000 1,088,000 804,000 904,000 736,000 681,000 4,251,000 7,187,000 3,784,000 2,884,000 2,243,000 968,000 1,994,000 1,931,000 1,541,000 2,621,000 3,980,000 3,607,000 1,774,000 660,000 638,000 1,542,000 1,145,000 941,000 2,706,000 3,197,000 3,241,000 
  accrued liabilities            58,770,000 53,289,000 60,665,000 62,266,000                                                                           
  accrued compensation            18,653,000 13,639,000 28,581,000 19,554,000 15,939,000 10,149,000 25,591,000 16,283,000 13,021,000 8,949,000 19,140,000 13,954,000 10,218,000 16,271,000 22,208,000            2,550,000 1,584,000 3,032,000 2,071,000 1,371,000 1,953,000 1,889,000 1,359,000 2,207,000 1,581,000 849,000 510,000 795,000                                        
  marketable securities, long-term             29,551,000                                                                             
  accrued expenses                45,553,000 41,289,000 37,807,000 35,149,000 31,924,000 32,687,000 40,375,000 38,908,000 49,363,000 38,317,000 38,254,000 40,368,000 29,046,000 21,074,000 29,339,000 18,802,000 14,548,000 14,143,000 14,528,000 13,513,000 10,495,000 9,903,000 6,012,000 5,976,000 3,547,000 4,546,000 3,143,000 5,652,000 3,188,000 5,329,000 2,933,000 836,000 1,882,000 193,000 800,000 1,548,000 1,162,000 915,000                                     
  other current liabilities                     78,000 280,000 130,000 234,000 82,000 1,529,000 472,000 630,000 556,000 646,000 616,000 694,000 674,000 647,000 716,000 686,000 682,000 701,000 716,000                                                   
  lease liabilities                       11,985,000 9,184,000 9,359,000                                                                 
  long-term lease liabilities                       31,417,000 33,530,000 35,709,000                                                                 
  right-of-use assets                         44,609,000                                                                 
  intangible assets                           59,941,000                                                               
  long-term debt                           311,861,000 307,156,000 302,706,000                                                             
  in-process research and development                            58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 58,200,000 77,900,000 77,900,000 77,900,000                                    
  accumulated other comprehensive                                                                                          
  current portion of long term debt                                       24,989,000 5,178,000 3,281,000 5,187,000 7,055,000 4,650,000 4,875,000 3,007,000                                            
  accrued lease expense, current                                        317,000 314,000 310,000 303,000 301,000 298,000 295,000 291,000 288,000 285,000 278,000                                        
  deferred rent                                        321,000 167,000 121,000 134,000 139,000 144,000 149,000 151,000 152,000 154,000 156,000 154,000 150,000 150,000 150,000 132,000 132,000 132,000 132,000 103,000 103,000 103,000 168,000 115,000 115,000 115,000 115,000 54,000 54,000 54,000 54,000                    
  capital lease obligations, current                                        16,000 32,000 48,000 64,000 69,000 83,000 96,000 109,000 117,000 115,000 114,000 55,000 64,000 72,000 81,000                                    
  accrued lease expense, long-term                                        185,000 250,000 315,000 449,000 514,000 580,000 647,000 717,000 784,000 852,000 923,000                                        
  certificate of deposit                                            2,195,000 2,173,000 2,153,000 2,132,000 2,111,000 2,091,000 2,085,000 2,085,000 2,085,000 2,176,000 2,176,000 2,085,000 2,085,000 2,085,000 2,085,000 2,085,000 2,085,000 2,085,000                             
  capital lease obligations, long-term                                           16,000 32,000 48,000 64,000 80,000 101,000 131,000 166,000 45,000 58,000 71,000 83,000                                    
  warrant to purchase common stock                                                                                          
  warrant to purchase 329,932 shares of common stock for 2.94 per share at march 31, 2013 and december 31, 2012                                             790,000                                             
  short-term investments                                               44,759,000 44,560,000 48,739,000 61,424,000 72,751,000 82,123,000 80,624,000 97,306,000 114,605,000 113,472,000 103,147,000 109,441,000 95,144,000                               
  liabilities and stockholders' equity                                                                                          
  commitments and contingencies                                                                                          
  stockholders' equity:                                                                                          
  common stock; .01 par value; 500,000,000 authorized shares, 31,488,204 and 24,833,301 issued and outstanding shares at december 31, 2012 and 2011, respectively                                              315,000                                            
  warrant to purchase 329,932 shares of common stock for 2.94 per share at december 31, 2012                                              790,000                                            
  accumulated other comprehensive income:                                                                                          
  unrealized gain on investments, net of taxes                                                                                          
  total stockholders' equity                                              120,882,000 136,612,000 119,716,000 128,134,000 134,267,000 142,342,000 176,738,000                                      
  total liabilities and stockholders' equity                                              153,561,000 152,457,000 136,052,000 133,253,000 139,833,000 146,069,000 180,288,000 190,470,000 196,265,000 126,978,000 127,404,000 126,890,000 126,695,000 124,629,000 125,300,000 129,820,000 4,758,000 8,148,000       28,348,000                  55,306,000  
  other                                               125,000 133,000                                          
  debt, current                                               592,000                                           
  common stock; .01 par value; authorized shares 500,000,000; issued and outstanding shares, 31,178,954 in 2012 and 24,833,301 in 2011                                               312,000                                           
  unrealized gain on investments                                               835,000 636,000 666,000 450,000 871,000 1,117,000 814,000 993,000                                    
  common stock; .01 par value; authorized shares 500,000,000; issued and outstanding shares, 24,874,852 in 2012 and 24,833,301 in 2011                                                249,000 249,000                                         
  deposits                                                 135,000 212,000 377,000 378,000                                      
  deferred revenue                                                   421,000 195,000 244,000 402,000 98,000 438,000 477,000 398,000 231,000 270,000 232,000                           1,583,000 1,619,000 
  common stock; .01 par value; authorized shares 500,000,000; issued and outstanding shares, 24,833,301 in 2011 and 15,653,734 in 2010                                                  248,000                                        
  preferred stock; .01 par value; authorized shares 200,000,000; issued and outstanding shares, zero in 2011 and 9,174,589 in 2010                                                                                          
  prepaid expenses                                                   343,000 354,000 169,000 277,000 364,000 341,000 82,000 159,000 236,000 145,000 30,000 74,000 118,000 193,000 110,000 244,000                        
  common stock; .01 par value; authorized shares                                                                                          
  500,000,000; issued and outstanding shares, 24,833,301 in 2011 and 15,653,734 in 2010                                                   248,000 248,000                                      
  preferred stock; .01 par value; authorized shares                                                                                          
  200,000,000; issued and outstanding shares, zero in 2011 and 9,174,589 in 2010                                                                                          
  see accompanying notes to unaudited consolidated financial statements                                                                                          
  restricted stock units compensation liability                                                     132,000                                     
  500,000,000; issued and outstanding shares, 24,828,101 in 2011 and 15,653,734 in 2010                                                     248,000                                     
  income tax receivable                                                       59,000  2,023,000 2,023,000                                
  long-term assets:                                                                                          
  deferred financing costs                                                          2,000 7,000 13,000 51,000 70,000 92,000 117,000 142,000 170,000 184,000 193,000 201,000 209,000 254,000 262,000 270,000 532,000 1,510,000 1,666,000 1,827,000             
  total long-term assets                                                      87,468,000 2,085,000 2,085,000 2,085,000 2,087,000 2,092,000 2,098,000 2,136,000 2,165,000 2,187,000 2,266,000 2,345,000 2,527,000 2,913,000 2,960,000 3,033,000 2,925,000 7,597,000 6,121,000 3,115,000 3,667,000 4,648,000               
  accrued project costs & other                                                      139,000 1,150,000 1,150,000 1,196,000 1,150,000 1,224,000 670,000 795,000 936,000 679,000 1,035,000 515,000 503,000 601,000 413,000 568,000 1,115,000 226,000 1,353,000 4,000 1,990,000                
  payroll liabilities                                                      1,117,000 481,000 386,000 225,000 580,000 421,000 1,035,000 5,048,000 453,000 633,000 1,178,000 799,000 631,000 1,284,000 1,243,000 2,114,000 1,302,000 2,152,000 1,690,000 926,000 1,574,000 1,364,000 1,034,000 1,407,000 1,183,000 949,000 538,000 359,000 205,000 196,000 227,000 237,000 358,000 323,000 442,000 458,000 
  interest payable                                                          1,000 2,000 3,000 10,000 13,000 15,000 18,000 20,000 23,000 23,000 23,000 23,000 23,000 27,000 28,000 28,000 52,000 106,000 315,000 80,000             
  convertible debt                                                          231,000 461,000 692,000 2,211,000 2,211,000 2,211,000 2,211,000 2,211,000 2,211,000 1,708,000 1,139,000 5,125,000 5,125,000 6,013,000 6,013,000 6,013,000 11,438,000 24,176,000 35,000,000 35,000,000             
  debt discount                                                          -23,000 -64,000 -118,000 -476,000 -596,000 -584,000 -784,000 -865,000 -950,000 -578,000 -403,000 -1,891,000 -1,964,000 -2,389,000 -2,466,000 -2,539,000 -5,001,000 -9,676,000 -15,186,000 -16,369,000             
  net convertible debt                                                          208,000 397,000 574,000 1,735,000 1,615,000 1,627,000 1,427,000 1,346,000 1,261,000 1,130,000 736,000 3,234,000 3,161,000 3,624,000 3,547,000 3,474,000 6,437,000 14,500,000 19,814,000 18,631,000             
  long-term liabilities:                                                                                          
  500,000,000; issued and outstanding shares, 15,653,734 in 2010 and 13,020,810 in 2009                                                      1,565,000                                    
  200,000,000; issued and outstanding shares, 9,174,589 in 2010 and zero in 2009                                                      918,000                                    
  net stockholders' equity                                                      192,843,000 124,686,000 124,386,000 124,427,000 123,914,000 121,045,000 120,684,000 116,436,000 -2,823,000 734,000       13,880,000                  46,634,000  
  500,000,000; issued and outstanding shares, 130,345,819 in 2010 and 130,208,099 in 2009                                                       1,303,000                                   
  unrealized gain on investment                                                       1,591,000 1,047,000 775,000 445,000                                
  500,000,000; issued and outstanding shares, 130,295,819 in 2009 and 122,494,010 in 2008                                                        1,303,000                                  
  common stock; .01 par value; authorized shares 500,000,000; issued and outstanding shares, 130,208,099 in 2009 and 122,494,010 in 2008                                                         1,302,000 1,302,000 1,302,000                               
  accumulated other comprehensive gain:                                                                                          
  restricted cash, long-term                                                                                          
  restricted stock unit liability                                                              113,000  12,000                          
  net long-term convertible debt                                                              487,000 820,000 1,346,000 1,735,000 2,113,000 2,261,000 2,574,000                      
  asset retirement obligation                                                              2,217,000 2,217,000 2,217,000 2,217,000 2,217,000 2,069,000 1,921,000 1,773,000 1,626,000 1,478,000 1,330,000 1,182,000 1,034,000 887,000 739,000 591,000 443,000 254,000 137,000          
  stockholders' equity                                                                                          
  income taxes payable                                                           625,000 1,250,000 2,794,000                             
  cash, cash equivalents and short-term investments                                                            122,846,000 127,540,000 2,397,000 5,771,000 9,447,000 12,030,000 16,479,000                        
  common stock; .01 par value; authorized shares 500,000,000; issued and outstanding shares, 129,433,099 in 2009 and 122,494,010 in 2008                                                            1,294,000                              
  common stock; .01 par value; authorized shares 500,000,000; issued and outstanding shares, 124,972,146 in 2009 and 122,494,010 in 2008                                                             1,250,000                             
  restricted cash - long term                                                              2,095,000 2,095,000 2,095,000 2,095,000   2,325,000 2,325,000 2,708,000 2,830,000 2,830,000 2,830,000  3,118,000 3,118,000 3,118,000             
  investments                                                                54,000 108,000 258,000 399,000 437,000 500,000                     
  property and equipment                                                                  4,000 4,000 5,000 7,000 8,000  3,029,000 15,000 17,000 20,000 22,000 24,000 27,000 30,000 37,000 47,000 61,000 76,000 99,000 127,000 157,000 188,000 940,000 1,054,000 
  deferred income                                                              302,000 191,000 825,000 271,000 245,000                        
  common stock; .01 par value; authorized shares 500,000,000; issued and outstanding shares, 122,494,010 in 2008 and 121,904,312 in 2007                                                              1,225,000                            
  accumulated other comprehensive loss:                                                                                          
  unrealized loss on investment                                                                  -242,000 -101,000 -63,000                      
  common stock; .01 par value; authorized shares 500,000,000; issued and outstanding shares, 122,315,635 in 2008 and 121,904,312 in 2007                                                               1,223,000                           
  liabilities and stockholders’ equity                                                                                          
  stockholders’ equity:                                                                                          
  common stock; .01 par value; authorized shares 500,000,000; issued and outstanding shares, 122,305,635 in 2008 and 121,904,312 in 2007                                                                1,223,000                          
  net stockholders’ equity                                                                2,695,000  11,488,000 14,424,000 18,278,000 3,691,000   45,901,000 54,579,000 10,529,000 6,288,000 9,118,000 17,549,000 7,235,000 4,907,000 12,466,000 21,461,000 26,220,000 28,651,000 18,087,000 21,250,000  41,928,000  53,606,000 
  total liabilities and stockholders’ equity                                                                11,956,000  19,500,000 22,582,000 25,923,000 15,708,000   56,854,000 62,640,000 22,870,000 25,741,000 33,736,000 41,125,000 13,011,000 11,607,000 18,860,000 25,338,000 29,812,000 32,610,000 22,573,000 25,370,000 28,308,000 49,345,000  62,638,000 
  restricted cash                                                                   492,000 493,000 493,000 407,000 285,000 285,000 285,000 285,000 285,000 285,000 285,000 285,000 285,000 285,000          
  inventories                                                                      576,000 1,821,000 1,797,000                  
  restricted cash—long term                                                                  2,095,000        3,118,000                
  common stock; .01 par value; authorized shares 500,000,000; issued and outstanding shares, 121,904,312 in 2007 and 101,328,118 in 2006                                                                  1,219,000                        
  other current assets                                                                   239,000 211,000 35,000 87,000 139,000 190,000 33,000 83,000 132,000 190,000 100,000 174,000 480,000 1,186,000 384,000 225,000 345,000 466,000 127,000 615,000 860,000 450,000 175,000 
  restricted cash —long term                                                                   2,326,000                       
  common stock; .01 par value; authorized shares 500,000,000; issued and outstanding shares, 121,708,316 in 2007 and 101,328,118 in 2006                                                                   1,217,000 1,217,000                      
  common stock; .01 par value; authorized shares 500,000,000; issued and outstanding shares, 101,327,502 in 2007 and 101,328,118 in 2006                                                                     1,013,000                     
  common stock; .01 par value; authorized shares 500,000,000; issued and outstanding shares, 101,328,118 in 2006 and 66,525,792 in 2005                                                                      1,013,000                    
  property, plant and equipment                                                                       4,513,000                   
  restructuring reserve                                                                       37,000 121,000 204,000 286,000 360,000 360,000 360,000 360,000 334,000 334,000 334,000 334,000 287,000 287,000 287,000 310,000 921,000   
  common stock; .01 par value; authorized shares 500,000,000; issued and outstanding shares, 100,240,903 in 2006 and 66,525,792 in 2005                                                                       1,002,000                   
  net shareholders’ equity                                                                       33,753,000                   
  common stock; .01 par value; authorized shares 500,000,000; issued and outstanding shares, 100,228,903 in 2006 and 66,525,792 in 2005                                                                        1,002,000                  
  common stock; .01 par value; authorized shares 500,000,000; issued and outstanding shares, 100,150,700 in 2006 and 66,525,792 in 2005                                                                         1,001,000                 
  restructuring reserve-long-term portion                                                                           47,000 127,000 207,000    570,000 646,000 738,000 822,000 907,000  952,000   
  common stock; .01 par value; authorized share 500,000,000; issued and outstanding shares, 66,525,792 in 2005 and 44,893,496 in 2004                                                                          665,000                
  additional capital                                                                          264,522,000 247,526,000 236,685,000 236,592,000 220,515,000 212,415,000 212,378,000 212,362,000 212,362,000 212,342,000 199,432,000 199,355,000 199,344,000 199,328,000 199,328,000 199,194,000 
  accrued project costs                                                                           195,000 298,000 759,000 884,000 767,000 1,284,000 840,000 1,747,000 2,100,000 1,608,000  2,283,000    
  common stock; .01 par value; authorized share 500,000,000; issued and outstanding shares, 53,518,863 in 2005 and 38,409,643 in 2004                                                                           535,000               
  common stock; .01 par value; authorized share 500,000,000; issued and outstanding shares, 45,090,629 in 2005 and 38,403,643 in 2004                                                                            450,000              
  common stock; .01 par value; authorized share 500,000,000; issued and outstanding shares, 44,987,287 in 2005 and 44,893,496 in 2004                                                                             450,000             
  restricted cash—long-term portion                                                                              3,303,000            
  restructuring reserve—long-term portion                                                                              285,000            
  restricted cash - long-term portion                                                                               3,303,000 3,297,000          
  restructuring reserve - long-term portion                                                                               416,000 494,000          
  due from taisho pharmaceutical co., ltd.                                                                                      199,000 1,733,000 2,266,000 3,659,000 
  accrued project costs and other                                                                                     1,544,000  2,515,000 3,307,000 3,571,000 
  deferred revenue — current portion                                                                                          
  restructuring reserve — long-term portion                                                                                      968,000    
  total stockholders’ equity                                                                                      23,448,000    
  deferred revenue - current portion                                                                                        143,000  
  see accompanying notes.                                                                                          
  deferred revenue—current portion                                                                                         143,000 

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