DexCom, Inc(NASDAQ:DXCM)

DexCom, Inc., a medical device company, focuses on the design, development, and commercialization of continuous glucose monitoring (CGM) systems in the United States and internationally. The company offers its systems for use by people with diabetes, as well as for use by healthcare providers. Its p...
Website: http://www.dexcom.com
Founded: 1999
Full Time Employees: 3,900
CEO: Kevin R. Sayer
Sector: Healthcare
Industry: Diagnostics & Research
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Quarterly
Annual
| Unit: USD | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | 2017-12-31 | 2017-09-30 | 2017-06-30 | 2017-03-31 | 2016-12-31 | 2016-09-30 | 2016-06-30 | 2016-03-31 | 2015-12-31 | 2015-09-30 | 2015-06-30 | 2015-03-31 | 2014-12-31 | 2014-09-30 | 2014-06-30 | 2014-03-31 | 2013-12-31 | 2013-09-30 | 2013-06-30 | 2013-03-31 | 2012-12-31 | 2012-09-30 | 2012-06-30 | 2012-03-31 | 2011-12-31 | 2011-09-30 | 2011-06-30 | 2011-03-31 | 2010-12-31 | 2010-09-30 | 2010-06-30 | 2010-03-31 | 2009-12-31 | 2009-09-30 | 2009-06-30 | 2009-03-31 | 2008-12-31 | 2008-09-30 | 2008-06-30 | 2008-03-31 | 2007-12-31 | 2007-09-30 | 2006-12-31 | 2005-12-31 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
revenue | 1,191,900,000 | 1,259,600,000 | 1,209,300,000 | 1,157,100,000 | 1,036,000,000 | 1,113,500,000 | 994,200,000 | 1,004,300,000 | 921,000,000 | 1,034,500,000 | 975,000,000 | 871,300,000 | 741,500,000 | 815,200,000 | 769,600,000 | 696,200,000 | 628,800,000 | 698,200,000 | 650,200,000 | 595,100,000 | 505,000,000 | 568,900,000 | 500,900,000 | 451,800,000 | 405,100,000 | 462,800,000 | 396,300,000 | 336,400,000 | 280,500,000 | 338,000,000 | 266,700,000 | 242,500,000 | 184,400,000 | 124,375,000 | 184,600,000 | 170,600,000 | 142,300,000 | 116,200,000 | 1,528,000 | 1,224,000 | |||||||||||||||||||||||||||||||||||||
yoy | 15.05% | 13.12% | 21.64% | 15.21% | 12.49% | 7.64% | 1.97% | 15.26% | 24.21% | 26.90% | 26.69% | 25.15% | 17.92% | 16.76% | 18.36% | 16.99% | 24.51% | 22.73% | 29.81% | 31.72% | 24.66% | 22.93% | 26.39% | 34.30% | 44.42% | 36.92% | 48.59% | 38.72% | 52.11% | 171.76% | 44.47% | 42.15% | 29.59% | 22.46% | |||||||||||||||||||||||||||||||||||||||||||
qoq | -5.37% | 4.16% | 4.51% | 11.69% | -6.96% | 12.00% | -1.01% | 9.04% | -10.97% | 6.10% | 11.90% | 17.51% | -9.04% | 5.93% | 10.54% | 10.72% | -9.94% | 7.38% | 9.26% | 17.84% | -11.23% | 13.58% | 10.87% | 11.53% | -12.47% | 16.78% | 17.81% | 19.93% | -17.01% | 26.73% | 9.98% | 31.51% | 48.26% | -32.62% | 8.21% | 19.89% | 24.84% | ||||||||||||||||||||||||||||||||||||||||
cost of sales | 441,600,000 | 466,900,000 | 477,900,000 | 468,300,000 | 447,000,000 | 457,700,000 | 400,400,000 | 377,600,000 | 359,100,000 | 377,900,000 | 351,700,000 | 324,900,000 | 278,900,000 | 273,900,000 | 275,400,000 | 246,700,000 | 230,700,000 | 225,600,000 | 203,300,000 | 178,000,000 | 161,100,000 | 169,800,000 | 160,500,000 | 167,700,000 | 148,600,000 | 153,500,000 | 149,400,000 | 129,900,000 | 111,700,000 | 115,200,000 | 98,100,000 | 88,900,000 | 65,500,000 | 67,500,000 | 57,600,000 | 53,100,000 | 48,200,000 | 35,100,000 | 47,500,000 | 51,800,000 | 41,100,000 | 3,655,000 | 3,113,000 | ||||||||||||||||||||||||||||||||||
gross profit | 750,300,000 | 792,700,000 | 731,400,000 | 688,800,000 | 589,000,000 | 655,800,000 | 593,800,000 | 626,700,000 | 561,900,000 | 656,600,000 | 623,300,000 | 546,400,000 | 462,600,000 | 541,300,000 | 494,200,000 | 449,500,000 | 398,100,000 | 472,600,000 | 446,900,000 | 417,100,000 | 343,900,000 | 399,100,000 | 340,400,000 | 284,100,000 | 256,500,000 | 309,300,000 | 246,900,000 | 206,500,000 | 168,800,000 | 222,800,000 | 168,600,000 | 153,600,000 | 118,900,000 | 153,500,000 | 127,000,000 | 117,500,000 | 94,100,000 | 116,700,000 | 101,100,000 | 85,500,000 | 75,100,000 | 91,200,000 | 74,700,000 | 66,000,000 | 46,500,000 | 59,400,000 | 47,200,000 | 39,900,000 | 29,800,000 | 34,100,000 | 27,600,000 | 21,900,000 | 16,500,000 | 17,568,000 | 8,402,000 | 11,243,000 | 9,387,000 | 10,693,000 | 8,164,000 | ||||||||||||||||||
yoy | 27.39% | 20.88% | 23.17% | 9.91% | 4.82% | -0.12% | -4.73% | 14.70% | 21.47% | 21.30% | 26.12% | 21.56% | 16.20% | 14.54% | 10.58% | 7.77% | 15.76% | 18.42% | 31.29% | 46.81% | 34.07% | 29.03% | 37.87% | 37.58% | 51.95% | 38.82% | 46.44% | 34.44% | 41.97% | 45.15% | 32.76% | 30.72% | 26.35% | 31.53% | 25.62% | 37.43% | 25.30% | 27.96% | 35.34% | 29.55% | 61.51% | 53.54% | 58.26% | 65.41% | 56.04% | 74.19% | 71.01% | 82.19% | 80.61% | 94.10% | 228.49% | 94.79% | 75.78% | 64.29% | 2.92% | ||||||||||||||||||||||
qoq | -5.35% | 8.38% | 6.18% | 16.94% | -10.19% | 10.44% | -5.25% | 11.53% | -14.42% | 5.34% | 14.07% | 18.12% | -14.54% | 9.53% | 9.94% | 12.91% | -15.76% | 5.75% | 7.14% | 21.29% | -13.83% | 17.24% | 19.82% | 10.76% | -17.07% | 25.27% | 19.56% | 22.33% | -24.24% | 32.15% | 9.77% | 29.18% | -22.54% | 20.87% | 8.09% | 24.87% | -19.37% | 15.43% | 18.25% | 13.85% | -17.65% | 22.09% | 13.18% | 41.94% | -21.72% | 25.85% | 18.30% | 33.89% | -12.61% | 23.55% | 26.03% | 32.73% | -6.08% | 109.09% | -25.27% | 19.77% | -12.21% | 30.98% | |||||||||||||||||||
gross margin % | 62.95% | 62.93% | 60.48% | 59.53% | 56.85% | 58.90% | 59.73% | 62.40% | 61.01% | 63.47% | 63.93% | 62.71% | 62.39% | 66.40% | 64.22% | 64.56% | 63.31% | 67.69% | 68.73% | 70.09% | 68.10% | 70.15% | 67.96% | 62.88% | 63.32% | 66.83% | 62.30% | 61.39% | 60.18% | 65.92% | 63.22% | 63.34% | 64.48% | 123.42% | 68.80% | 68.87% | 66.13% | Infinity% | Infinity% | Infinity% | 64.63% | Infinity% | Infinity% | Infinity% | Infinity% | Infinity% | Infinity% | Infinity% | Infinity% | Infinity% | Infinity% | Infinity% | Infinity% | Infinity% | Infinity% | Infinity% | Infinity% | Infinity% | Infinity% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | NaN% | 0% | 0% | ||
operating expenses: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
research and development | 145,300,000 | 148,200,000 | 157,500,000 | 148,200,000 | 145,200,000 | 139,500,000 | 135,400,000 | 136,000,000 | 141,500,000 | 136,100,000 | 131,400,000 | 119,300,000 | 119,000,000 | 116,300,000 | 110,300,000 | 121,700,000 | 135,900,000 | 149,800,000 | 128,800,000 | 129,100,000 | 109,400,000 | 119,200,000 | 87,700,000 | 79,900,000 | 73,100,000 | 78,800,000 | 66,700,000 | 69,000,000 | 59,000,000 | 57,600,000 | 50,100,000 | 47,200,000 | 44,800,000 | 48,700,000 | 43,300,000 | 45,300,000 | 48,100,000 | 43,700,000 | 43,900,000 | 36,300,000 | 32,200,000 | 28,500,000 | 64,800,000 | 24,400,000 | 19,800,000 | 21,600,000 | 18,500,000 | 14,800,000 | 14,500,000 | 12,600,000 | 11,800,000 | 11,100,000 | 9,300,000 | 8,705,000 | 10,582,000 | 10,498,000 | 9,715,000 | 9,232,000 | 8,231,000 | 7,016,000 | 6,268,000 | 6,902,000 | 6,161,000 | 5,425,000 | 4,739,000 | 4,172,000 | 3,496,000 | 3,455,000 | 3,171,000 | 4,571,000 | 5,418,000 | 4,797,000 | 4,843,000 | 4,397,000 | 3,671,000 | ||
selling, general and administrative | 349,700,000 | 321,500,000 | 331,400,000 | 328,000,000 | 310,100,000 | 327,400,000 | 306,400,000 | 332,700,000 | 319,300,000 | 308,800,000 | 284,700,000 | 297,300,000 | 294,600,000 | 297,800,000 | 234,600,000 | 248,900,000 | 220,900,000 | 235,100,000 | 199,800,000 | 187,000,000 | 188,600,000 | 175,900,000 | 158,600,000 | 136,400,000 | 149,800,000 | 129,000,000 | 124,200,000 | 138,300,000 | 124,200,000 | 112,100,000 | 104,600,000 | 111,300,000 | 104,800,000 | 92,800,000 | 84,200,000 | 85,800,000 | 86,400,000 | 79,100,000 | 75,700,000 | 69,300,000 | 62,100,000 | 61,100,000 | 52,300,000 | 45,200,000 | 39,400,000 | 36,200,000 | 33,700,000 | 30,900,000 | 27,600,000 | 23,800,000 | 21,600,000 | 20,700,000 | 18,100,000 | 17,195,000 | 15,142,000 | 15,394,000 | 15,069,000 | 13,737,000 | 13,241,000 | 12,244,000 | 10,718,000 | 9,973,000 | 10,377,000 | 10,362,000 | 9,794,000 | 9,397,000 | 8,948,000 | 8,952,000 | 7,903,000 | 7,349,000 | 6,652,000 | 7,247,000 | 6,421,000 | 5,653,000 | 5,943,000 | ||
total operating expenses | 495,000,000 | 469,700,000 | 488,900,000 | 476,200,000 | 455,300,000 | 466,900,000 | 441,800,000 | 468,700,000 | 460,800,000 | 439,700,000 | 417,800,000 | 418,300,000 | 415,400,000 | 415,900,000 | 346,700,000 | 372,500,000 | 356,800,000 | 472,000,000 | 328,600,000 | 316,100,000 | 298,000,000 | 295,100,000 | 246,300,000 | 216,300,000 | 222,900,000 | 207,800,000 | 190,900,000 | 207,300,000 | 183,200,000 | 387,400,000 | 154,700,000 | 158,500,000 | 149,600,000 | 141,500,000 | 127,500,000 | 131,100,000 | 134,500,000 | 122,800,000 | 119,600,000 | 105,600,000 | 94,300,000 | 89,600,000 | 117,100,000 | 69,600,000 | 59,200,000 | 57,800,000 | 52,200,000 | 45,700,000 | 42,100,000 | 36,400,000 | 33,400,000 | 31,800,000 | 27,400,000 | 25,900,000 | 25,724,000 | 25,892,000 | 24,784,000 | 22,969,000 | 21,472,000 | 19,260,000 | 16,986,000 | 16,875,000 | 16,538,000 | 15,787,000 | 14,533,000 | 13,569,000 | 12,444,000 | 12,407,000 | 11,074,000 | 11,920,000 | 12,070,000 | 12,044,000 | 11,264,000 | 10,050,000 | 9,614,000 | ||
operating income | 255,300,000 | 323,000,000 | 242,500,000 | 212,600,000 | 133,700,000 | 188,900,000 | 152,000,000 | 158,000,000 | 101,100,000 | 216,900,000 | 205,500,000 | 128,100,000 | 47,200,000 | 125,400,000 | 147,500,000 | 77,000,000 | 41,300,000 | 600,000 | 118,300,000 | 101,000,000 | 45,900,000 | 104,000,000 | 94,100,000 | 67,800,000 | 33,600,000 | 101,500,000 | 56,000,000 | -800,000 | -14,400,000 | -164,600,000 | 13,900,000 | -4,900,000 | -30,700,000 | 12,000,000 | -500,000 | -13,600,000 | -40,400,000 | -6,100,000 | -18,500,000 | -20,100,000 | -19,200,000 | 1,600,000 | -42,400,000 | -3,600,000 | -12,700,000 | 1,600,000 | -5,000,000 | -5,800,000 | -12,300,000 | -2,300,000 | -5,800,000 | -9,900,000 | -10,900,000 | -8,332,000 | -17,322,000 | -14,649,000 | -15,397,000 | -12,276,000 | -13,308,000 | -7,389,000 | -11,870,000 | -9,886,000 | -13,062,000 | -11,268,000 | -11,074,000 | -9,462,000 | -11,579,000 | -13,455,000 | -11,337,000 | -12,738,000 | -13,990,000 | -13,455,000 | -12,644,000 | ||||
yoy | 90.95% | 70.99% | 59.54% | 34.56% | 32.25% | -12.91% | -26.03% | 23.34% | 114.19% | 72.97% | 39.32% | 66.36% | 14.29% | 20800.00% | 24.68% | -23.76% | -10.02% | -99.42% | 25.72% | 48.97% | 36.61% | 2.46% | 68.04% | -8575.00% | -333.33% | -161.66% | 302.88% | -83.67% | -53.09% | -1471.67% | -2880.00% | -63.97% | -24.01% | -296.72% | -97.30% | -32.34% | 110.42% | -481.25% | -56.37% | 458.33% | 51.18% | 0.00% | 748.00% | -37.93% | 3.25% | -169.57% | -13.79% | -41.41% | 12.84% | -72.40% | -66.52% | -32.42% | -29.21% | -32.13% | 30.16% | 98.25% | 29.71% | 24.18% | 1.88% | -34.42% | 7.19% | 4.48% | 12.81% | -16.25% | -2.32% | -25.72% | -17.23% | 0.00% | -10.34% | ||||||||
qoq | -20.96% | 33.20% | 14.06% | 59.01% | -29.22% | 24.28% | -3.80% | 56.28% | -53.39% | 5.55% | 60.42% | 171.40% | -62.36% | -14.98% | 91.56% | 86.44% | 6783.33% | -99.49% | 17.13% | 120.04% | -55.87% | 10.52% | 38.79% | 101.79% | -66.90% | 81.25% | -7100.00% | -94.44% | -91.25% | -1284.17% | -383.67% | -84.04% | -355.83% | -2500.00% | -96.32% | -66.34% | 562.30% | -67.03% | -7.96% | 4.69% | -1300.00% | -103.77% | 1077.78% | -71.65% | -893.75% | -132.00% | -13.79% | -52.85% | 434.78% | -60.34% | -41.41% | -9.17% | 30.82% | -51.90% | 18.25% | -4.86% | 25.42% | -7.75% | 80.11% | -37.75% | 20.07% | -24.31% | 15.92% | 1.75% | 17.04% | -18.28% | -13.94% | 18.68% | -11.00% | -8.95% | 3.98% | 6.41% | |||||
operating margin % | 21.42% | 25.64% | 20.05% | 18.37% | 12.91% | 16.96% | 15.29% | 15.73% | 10.98% | 20.97% | 21.08% | 14.70% | 6.37% | 15.38% | 19.17% | 11.06% | 6.57% | 0.09% | 18.19% | 16.97% | 9.09% | 18.28% | 18.79% | 15.01% | 8.29% | 21.93% | 14.13% | -0.24% | -5.13% | -48.70% | 5.21% | -2.02% | -16.65% | 9.65% | -0.27% | -7.97% | -28.39% | -Infinity% | -Infinity% | -Infinity% | -16.52% | Infinity% | -Infinity% | -Infinity% | -Infinity% | Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | 0% | 0% | ||
other income | 14,200,000 | 17,700,000 | 109,800,000 | 28,500,000 | 20,600,000 | 22,400,000 | 25,400,000 | 29,800,000 | 31,400,000 | 30,300,000 | 33,900,000 | -1,150,000 | -1,600,000 | -5,600,000 | 2,600,000 | -100,000 | 1,300,000 | 1,800,000 | 400,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income before income taxes | 269,500,000 | 340,700,000 | 352,300,000 | 241,100,000 | 154,300,000 | 211,300,000 | 177,400,000 | 187,800,000 | 132,500,000 | 246,200,000 | 240,400,000 | 159,300,000 | 64,500,000 | 133,200,000 | 146,200,000 | 75,300,000 | 36,100,000 | -14,700,000 | 90,700,000 | 76,700,000 | 21,200,000 | 81,300,000 | 75,100,000 | 46,200,000 | 22,400,000 | 94,300,000 | 45,800,000 | -9,300,000 | -26,600,000 | -176,900,000 | 44,800,000 | 29,600,000 | -24,000,000 | 8,600,000 | -2,500,000 | -14,400,000 | -40,300,000 | -7,000,000 | -18,600,000 | -20,100,000 | -2,600,000 | -6,000,000 | -10,100,000 | -11,100,000 | -8,495,000 | -17,306,000 | -14,627,000 | -15,372,000 | |||||||||||||||||||||||||||||
income tax expense | 70,000,000 | 73,400,000 | 68,500,000 | 61,300,000 | 48,900,000 | 59,600,000 | 42,800,000 | 44,300,000 | -13,900,000 | -10,100,000 | 119,700,000 | 43,400,000 | 15,900,000 | 2,050,000 | 45,000,000 | 3,625,000 | 19,800,000 | 13,800,000 | -19,100,000 | -273,900,000 | 2,900,000 | -100,000 | 2,500,000 | 1,600,000 | 300,000 | 200,000 | 1,400,000 | 400,000 | 200,000 | 100,000 | -13,000 | -43,000 | 64,000 | -1,308,000 | |||||||||||||||||||||||||||||||||||||||||||
net income | 199,500,000 | 267,300,000 | 283,800,000 | 179,800,000 | 105,400,000 | 151,700,000 | 134,600,000 | 143,500,000 | 146,400,000 | 256,300,000 | 120,700,000 | 115,900,000 | 48,600,000 | 91,800,000 | 101,200,000 | 50,900,000 | 97,300,000 | -19,400,000 | 70,900,000 | 62,900,000 | 40,300,000 | 355,200,000 | 72,200,000 | 46,300,000 | 19,900,000 | 92,700,000 | 45,800,000 | -10,500,000 | -26,900,000 | -179,700,000 | 46,600,000 | 30,200,000 | -24,200,000 | -9,400,000 | -2,000,000 | 2,900,000 | -41,700,000 | -7,400,000 | -18,800,000 | -20,200,000 | -19,200,000 | 1,500,000 | -42,500,000 | -3,700,000 | -12,900,000 | 1,300,000 | -5,200,000 | -6,000,000 | -12,500,000 | -2,600,000 | -6,000,000 | -10,100,000 | -11,100,000 | -8,482,000 | -17,263,000 | -14,691,000 | -14,064,000 | -12,251,000 | -13,278,000 | -7,367,000 | -11,850,000 | -9,812,000 | -13,398,000 | -11,687,000 | -20,273,000 | -11,529,000 | -13,523,000 | -15,330,000 | -13,142,000 | -13,450,000 | -14,688,000 | -14,074,000 | -12,972,000 | -12,229,000 | -11,384,000 | ||
yoy | 89.28% | 76.20% | 110.85% | 25.30% | -28.01% | -40.81% | 11.52% | 23.81% | 201.23% | 179.19% | 19.27% | 127.70% | -50.05% | -573.20% | 42.74% | -19.08% | 141.44% | -105.46% | -1.80% | 35.85% | 102.51% | 283.17% | 57.64% | -540.95% | -173.98% | -151.59% | -1.72% | -134.77% | 11.16% | 1811.70% | -2430.00% | 941.38% | -41.97% | 27.03% | -89.36% | -114.36% | 117.19% | -593.33% | -55.76% | 445.95% | 48.84% | 15.38% | 717.31% | -38.33% | 3.20% | -150.00% | -13.33% | -40.59% | 12.61% | -69.35% | -65.24% | -31.25% | -21.08% | -30.76% | 30.01% | 99.42% | 18.68% | 24.86% | -0.90% | -36.96% | -41.55% | -14.89% | -0.92% | -23.76% | 54.26% | -14.28% | -7.93% | 8.92% | 1.31% | 9.98% | 29.02% | ||||||
qoq | -25.36% | -5.81% | 57.84% | 70.59% | -30.52% | 12.70% | -6.20% | -1.98% | -42.88% | 112.34% | 4.14% | 138.48% | -47.06% | -9.29% | 98.82% | -47.69% | -601.55% | -127.36% | 12.72% | 56.08% | -88.65% | 391.97% | 55.94% | 132.66% | -78.53% | 102.40% | -536.19% | -60.97% | -85.03% | -485.62% | 54.30% | -224.79% | 157.45% | 370.00% | -168.97% | -106.95% | 463.51% | -60.64% | -6.93% | 5.21% | -1380.00% | -103.53% | 1048.65% | -71.32% | -1092.31% | -125.00% | -13.33% | -52.00% | 380.77% | -56.67% | -40.59% | -9.01% | 30.87% | -50.87% | 17.51% | 4.46% | 14.80% | -7.73% | 80.24% | -37.83% | 20.77% | -26.77% | 14.64% | -42.35% | 75.84% | -14.75% | -11.79% | 16.65% | -2.29% | -8.43% | 4.36% | 8.50% | 6.08% | 7.42% | |||
net income margin % | 16.74% | 21.22% | 23.47% | 15.54% | 10.17% | 13.62% | 13.54% | 14.29% | 15.90% | 24.78% | 12.38% | 13.30% | 6.55% | 11.26% | 13.15% | 7.31% | 15.47% | -2.78% | 10.90% | 10.57% | 7.98% | 62.44% | 14.41% | 10.25% | 4.91% | 20.03% | 11.56% | -3.12% | -9.59% | -53.17% | 17.47% | 12.45% | -13.12% | -7.56% | -1.08% | 1.70% | -29.30% | -Infinity% | -Infinity% | -Infinity% | -16.52% | Infinity% | -Infinity% | -Infinity% | -Infinity% | Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -800.33% | -930.07% | ||
basic net income per share | 0.52 | 0.69 | 0.73 | 0.46 | 0.27 | 0.38 | 0.34 | 0.36 | 0.38 | 0.66 | 0.31 | 0.3 | 0.13 | 0.24 | 0.26 | 0.13 | 1 | -0.2 | 0.73 | 0.65 | 0.42 | 3.75 | 0.75 | 0.49 | 0.22 | 1.02 | 0.5 | -0.12 | 0.15 | 0.53 | 0.34 | -0.188 | -0.53 | -0.05 | -0.08 | ||||||||||||||||||||||||||||||||||||||||||
shares used to compute basic net income per share | 385.1 | -1.2 | 391.1 | 392.1 | 391.1 | -1 | 394.2 | 399.2 | 390.2 | -0.7 | 386.6 | 386.7 | 386.7 | -1 | 389.8 | 392.5 | 97.2 | 0.1 | 96.9 | 96.7 | 96.3 | 0.6 | 95.8 | 93.8 | 91.8 | 0.2 | 91.3 | 91.1 | 22 | 88.5 | 88.2 | 86.4 | 19.8 | 80.5 | 79.6 | 75 | |||||||||||||||||||||||||||||||||||||||||
diluted net income per share | 0.51 | 0.67 | 0.7 | 0.45 | 0.27 | 0.38 | 0.34 | 0.35 | 0.36 | 0.61 | 0.29 | 0.28 | 0.12 | 0.22 | 0.24 | 0.12 | 0.93 | -0.19 | 0.71 | 0.63 | 0.41 | 3.63 | 0.73 | 0.48 | 0.21 | 1.01 | 0.5 | -0.12 | 0.148 | 0.52 | 0.34 | -0.188 | -0.53 | -0.05 | -0.09 | ||||||||||||||||||||||||||||||||||||||||||
shares used to compute diluted net income per share | 393.6 | -2.2 | 407.4 | 408.2 | 407.5 | -2 | 410.2 | 416.8 | 416.7 | -2.8 | 426.8 | 431.5 | 418.5 | -0.5 | 425.8 | 421.4 | 107.2 | 0.3 | 100.5 | 99.6 | 99.4 | 0.6 | 99.5 | 97 | 94.1 | 0.1 | 92.5 | 91.1 | 22.325 | 90.3 | 89.4 | 19.8 | 80.5 | 79.6 | 75.3 | ||||||||||||||||||||||||||||||||||||||||||
amortization of intangible assets | 1,300,000 | 1,700,000 | 1,700,000 | 1,800,000 | 1,800,000 | 1,800,000 | 1,900,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income from equity investments | 250,000 | 1,000,000 | 200,000 | -4,200,000 | -4,900,000 | 34,900,000 | 42,700,000 | 7,400,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
interest expense | -5,900,000 | -4,600,000 | -4,700,000 | -4,600,000 | -4,700,000 | -4,600,000 | -25,200,000 | -25,100,000 | -25,200,000 | -24,800,000 | -24,600,000 | -24,400,000 | -20,300,000 | -15,400,000 | -15,300,000 | -15,100,000 | -15,000,000 | -14,900,000 | -8,200,000 | -4,900,000 | -4,800,000 | -4,800,000 | -4,700,000 | -4,500,000 | -3,100,000 | -500,000 | -300,000 | -200,000 | -100,000 | -100,000 | -100,000 | -100,000 | -200,000 | -200,000 | -200,000 | -200,000 | -200,000 | -300,000 | -200,000 | -200,000 | -200,000 | -198,000 | -1,000 | -1,000 | -1,000 | -1,000 | -3,000 | -6,000 | -8,000 | -44,000 | -197,000 | -1,299,000 | -2,098,000 | -2,037,000 | -1,982,000 | -1,928,000 | -879,000 | -913,000 | -926,000 | -893,000 | |||||||||||||||||
interest and other income | 37,100,000 | 21,900,000 | 12,500,000 | 3,300,000 | 3,000,000 | -800,000 | -1,000,000 | -1,700,000 | 900,000 | 100,000 | 1,900,000 | 5,900,000 | 4,100,000 | 4,200,000 | 8,100,000 | 4,900,000 | 6,500,000 | 6,900,000 | 35,000 | 17,000 | 23,000 | 25,000 | 80,750 | 93,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
* we adjusted our 2021 amounts to reflect the simplified convertible instruments accounting guidance, which we adopted on a full retrospective basis. all periods presented have also been adjusted to reflect the four-for-one stock split. refer to note 1, “organization and significant accounting policies,” for further information. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income tax benefit | 24,400,000 | -61,200,000 | 1,200,000 | -550,000 | -1,800,000 | -600,000 | -4,100,000 | -500,000 | -17,300,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
* we adjusted our 2021 amounts to reflect the simplified convertible instruments accounting guidance, which we adopted on a full retrospective basis. refer to note 1 “organization and significant accounting policies” for further information. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss on extinguishment of debt | -700,000 | -800,000 | -500,000 | -5,400,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss from equity investments | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
basic and diluted net income per share | -0.3 | -0.28 | -0.11 | -0.02 | 0.03 | -0.49 | -0.08 | -0.22 | -0.24 | -0.17 | -0.17 | -0.14 | -0.16 | -0.125 | -0.2 | -0.11 | -0.19 | -0.203 | -0.23 | -0.2 | -0.4 | -0.24 | -0.29 | -0.33 | -0.33 | -0.355 | -0.5 | -0.48 | -0.44 | -0.298 | -0.4 | ||||||||||||||||||||||||||||||||||||||||||||||
shares used to compute basic and diluted net income per share | 90.3 | 87.3 | 0.2 | 86.7 | 85.2 | 0.3 | 84.1 | 83.6 | 77.8 | 73.3 | 70.9 | 69.8 | 16,227.5 | 67,397 | 65,096 | 62,179 | 13,926.75 | 58,200 | 57,554 | 51,291 | 10,949.25 | 45,919 | 45,832 | 39,569 | 7,353.75 | 29,627 | 29,387 | 29,228 | 7,070,663.25 | 28,324,661 | |||||||||||||||||||||||||||||||||||||||||||||||
operating expenses | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
interest income | 1,550,000 | 2,500,000 | 2,200,000 | 1,500,000 | 1,400,000 | 1,200,000 | 500,000 | 200,000 | 100,000 | 100,000 | 100,000 | 100,000 | 25,000 | 31,000 | 25,000 | 26,000 | 22,000 | 20,000 | 23,000 | 30,000 | 107,000 | 123,000 | 133,000 | 215,000 | 307,000 | 565,000 | -52,000 | 119,000 | |||||||||||||||||||||||||||||||||||||||||||||||||
shares used to compute dilutive net income per share | 87.4 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
product revenue | 171,200,000 | 148,600,000 | 137,300,000 | 130,800,000 | 104,200,000 | 92,900,000 | 72,800,000 | 84,300,000 | 67,900,000 | 58,200,000 | 46,700,000 | 51,300,000 | 42,500,000 | 35,500,000 | 27,800,000 | 31,777,000 | 21,081,000 | 21,524,000 | 18,618,000 | 20,936,000 | 16,656,000 | 15,179,000 | 13,139,000 | 13,592,000 | 10,776,000 | 9,043,000 | 6,764,000 | 6,632,000 | 4,620,000 | 4,112,000 | 2,672,000 | 2,465,000 | 1,878,000 | 1,940,000 | |||||||||||||||||||||||||||||||||||||||||||
development grant and other revenue | 1,000,000 | 300,000 | 1,100,000 | 600,000 | 400,000 | 400,000 | 400,000 | 300,000 | 1,800,000 | 1,489,000 | 2,008,000 | 1,926,000 | 1,477,000 | 1,485,000 | 1,598,000 | 6,238,000 | 1,035,000 | 2,044,000 | 888,000 | 2,743,000 | 2,781,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
total revenue | 171,200,000 | 148,600,000 | 137,300,000 | 130,800,000 | 105,200,000 | 93,200,000 | 72,800,000 | 84,300,000 | 69,000,000 | 58,800,000 | 47,100,000 | 51,700,000 | 42,900,000 | 35,800,000 | 29,600,000 | 33,266,000 | 23,089,000 | 23,450,000 | 20,095,000 | 22,421,000 | 18,254,000 | 21,417,000 | 14,174,000 | 15,636,000 | 11,664,000 | 11,786,000 | 9,545,000 | 10,471,000 | 7,259,000 | 6,751,000 | 5,212,000 | 4,073,000 | 1,920,000 | 1,982,000 | |||||||||||||||||||||||||||||||||||||||||||
basic and diluted net loss per share | -0.23 | -0.095 | -0.08 | -0.168 | -0.25 | -0.21 | -0.21 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
shares used to compute basic and diluted net loss per share | 82.1 | 17.675 | 71.4 | 17,123.5 | 69,052 | 68,635 | 67,790 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
product cost of sales | 39,600,000 | 30,500,000 | 27,200,000 | 26,300,000 | 24,900,000 | 21,800,000 | 18,700,000 | 16,900,000 | 17,200,000 | 14,800,000 | 13,700,000 | 12,400,000 | 14,433,000 | 13,391,000 | 10,889,000 | 9,587,000 | 10,695,000 | 9,230,000 | 8,351,000 | 8,352,000 | 7,664,000 | 6,982,000 | 6,318,000 | 5,140,000 | 5,478,000 | 4,589,000 | 4,627,000 | 3,522,000 | 3,550,000 | 3,577,000 | 3,144,000 | 3,112,000 | |||||||||||||||||||||||||||||||||||||||||||||
development and other cost of sales | 200,000 | 400,000 | 400,000 | 500,000 | 200,000 | 700,000 | 1,265,000 | 1,296,000 | 1,318,000 | 1,121,000 | 1,033,000 | 860,000 | 1,195,000 | 706,000 | 983,000 | 1,206,000 | 949,000 | 946,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
total cost of sales | 39,600,000 | 30,500,000 | 27,200,000 | 26,300,000 | 24,900,000 | 21,800,000 | 18,900,000 | 17,300,000 | 17,600,000 | 15,300,000 | 13,900,000 | 13,100,000 | 15,698,000 | 14,687,000 | 12,207,000 | 10,708,000 | 11,728,000 | 10,090,000 | 9,546,000 | 9,058,000 | 8,647,000 | 8,188,000 | 7,267,000 | 6,086,000 | 6,364,000 | 6,394,000 | 7,799,000 | 5,475,000 | 4,891,000 | 3,840,000 | 3,393,000 | 3,242,000 | |||||||||||||||||||||||||||||||||||||||||||||
basic net loss per share | -0.08 | -0.07 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
shares used to compute basic net loss per share | 18.675 | 75.8 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
diluted net loss per share | -0.083 | -0.08 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
shares used to compute diluted net loss per share | 18.75 | 76.1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss on debt extinguishment upon conversion of convertible debt | -3,000 | -312,000 | -245,000 | -7,930,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
gross margin | 11,871,000 | 5,116,000 | 6,989,000 | 3,476,000 | 4,519,000 | 3,459,000 | 4,107,000 | 865,000 | -263,000 | -818,000 | -1,920,000 | -1,411,000 | -1,380,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
development grant revenue | 1,954,500 | 2,639,000 | 2,639,000 | 2,540,000 | 1,608,000 | 42,000 | 42,000 | 38,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
development cost of sales | 1,732,500 | 1,805,000 | 3,172,000 | 1,953,000 | 1,341,000 | 263,000 | 249,000 | 130,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
gross deficit | -1,048,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
product revenues | 1,824,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
total revenues | 1,862,000 |
Balance Sheets:
Quarterly
Annual
| Unit: USD | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | 2017-12-31 | 2017-09-30 | 2017-06-30 | 2017-03-31 | 2016-12-31 | 2016-09-30 | 2016-06-30 | 2016-03-31 | 2015-12-31 | 2015-09-30 | 2015-06-30 | 2015-03-31 | 2014-12-31 | 2014-09-30 | 2014-06-30 | 2014-03-31 | 2013-12-31 | 2013-09-30 | 2013-06-30 | 2013-03-31 | 2012-12-31 | 2012-09-30 | 2012-06-30 | 2012-03-31 | 2011-12-31 | 2011-09-30 | 2011-06-30 | 2011-03-31 | 2010-12-31 | 2010-09-30 | 2010-06-30 | 2010-03-31 | 2009-12-31 | 2009-09-30 | 2009-06-30 | 2009-03-31 | 2008-12-31 | 2008-09-30 | 2008-06-30 | 2008-03-31 | 2007-12-31 | 2007-09-30 | 2006-12-31 | 2005-12-31 |
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assets | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
current assets: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cash and cash equivalents | 1,118,200,000 | 917,700,000 | 1,835,700,000 | 1,159,000,000 | 904,900,000 | 606,100,000 | 621,200,000 | 939,200,000 | 851,200,000 | 566,300,000 | 643,700,000 | 1,194,900,000 | 623,200,000 | 642,300,000 | 698,100,000 | 735,400,000 | 716,000,000 | 1,052,600,000 | 1,444,300,000 | 1,158,800,000 | 733,800,000 | 817,600,000 | 673,500,000 | 530,000,000 | 584,600,000 | 446,200,000 | 395,600,000 | 709,200,000 | 1,285,100,000 | 1,137,000,000 | 367,400,000 | 300,200,000 | 420,400,000 | 441,500,000 | 402,100,000 | 395,900,000 | 153,500,000 | 94,500,000 | 97,700,000 | 87,500,000 | 77,900,000 | 86,100,000 | 85,300,000 | 67,700,000 | 54,200,000 | 71,800,000 | 63,200,000 | 49,500,000 | 45,700,000 | 43,200,000 | 33,400,000 | 28,200,000 | 18,900,000 | 8,100,000 | 4,744,000 | 5,985,000 | 5,119,000 | 2,553,000 | 17,523,000 | 33,889,000 | 3,805,000 | 4,889,000 | 5,529,000 | 6,090,000 | 10,700,000 | 3,577,000 | 6,362,000 | 4,208,000 | 9,276,000 | 12,700,000 | 4,642,000 | 4,963,000 | 23,952,000 | 23,115,000 | 15,176,000 | 18,167,066 | 37,247,064 |
short-term marketable securities | 1,297,000,000 | 1,081,000,000 | 1,486,400,000 | 1,770,300,000 | 1,796,500,000 | 1,973,300,000 | 1,871,100,000 | 2,181,500,000 | 2,045,800,000 | 2,157,800,000 | 2,596,600,000 | 2,441,300,000 | 1,943,800,000 | 1,813,900,000 | 1,673,800,000 | 2,019,400,000 | 1,972,200,000 | 1,678,600,000 | 1,253,600,000 | 1,426,100,000 | 1,898,800,000 | 1,890,100,000 | 1,930,300,000 | 1,978,800,000 | 925,900,000 | 1,087,100,000 | 1,034,300,000 | 668,300,000 | 72,900,000 | 248,600,000 | 301,300,000 | 305,900,000 | 113,500,000 | ||||||||||||||||||||||||||||||||||||||||||||
accounts receivable | 1,088,600,000 | 1,216,100,000 | 1,109,600,000 | 1,348,800,000 | 1,155,200,000 | 1,005,700,000 | 1,002,000,000 | 945,200,000 | 978,600,000 | 973,900,000 | 785,700,000 | 750,600,000 | 636,800,000 | 713,300,000 | 564,100,000 | 560,800,000 | 544,500,000 | 514,300,000 | 529,100,000 | 483,500,000 | 443,400,000 | 428,500,000 | 370,000,000 | 296,500,000 | 300,700,000 | 286,300,000 | 234,900,000 | 217,300,000 | 204,700,000 | 226,700,000 | 169,800,000 | 162,000,000 | 123,900,000 | 134,300,000 | 110,500,000 | 101,700,000 | 85,900,000 | 101,700,000 | 76,800,000 | 73,800,000 | 67,300,000 | 74,100,000 | 55,800,000 | 45,500,000 | 40,200,000 | 42,400,000 | 31,400,000 | 28,600,000 | 23,800,000 | 26,100,000 | 21,600,000 | 17,700,000 | 16,300,000 | 19,500,000 | 12,357,000 | 12,900,000 | 12,543,000 | 12,547,000 | 9,003,000 | 8,694,000 | 7,158,000 | 6,671,000 | 5,102,000 | 4,661,000 | 3,801,000 | 3,490,000 | 2,487,000 | 2,067,000 | 1,345,000 | 1,118,000 | 429,000 | 568,000 | 321,000 | 215,000 | 171,000 | 120,477 | |
inventory | 693,600,000 | 629,100,000 | 604,100,000 | 570,700,000 | 538,200,000 | 542,600,000 | 586,300,000 | 570,300,000 | 589,100,000 | 559,600,000 | 498,600,000 | 421,100,000 | 366,000,000 | 306,700,000 | 311,000,000 | 339,500,000 | 342,200,000 | 357,300,000 | 351,300,000 | 319,300,000 | 289,700,000 | 234,700,000 | 200,700,000 | 165,300,000 | 141,900,000 | 119,800,000 | 120,400,000 | 117,900,000 | 101,100,000 | 70,700,000 | 55,200,000 | 46,200,000 | 51,600,000 | 45,200,000 | 43,300,000 | 42,800,000 | 46,500,000 | 45,400,000 | 44,700,000 | 42,900,000 | 46,100,000 | 35,200,000 | 30,600,000 | 22,400,000 | 18,400,000 | 16,000,000 | 14,300,000 | 11,600,000 | 8,900,000 | 9,000,000 | 10,000,000 | 7,300,000 | 7,500,000 | 7,400,000 | 7,141,000 | 7,378,000 | 8,044,000 | 8,171,000 | 6,455,000 | 6,258,000 | 6,425,000 | 8,112,000 | 6,353,000 | 4,087,000 | 3,851,000 | 2,641,000 | 1,932,000 | 1,363,000 | 2,365,000 | 2,446,000 | 2,590,000 | 2,771,000 | 1,824,000 | 1,139,000 | 1,035,000 | 1,413,024 | |
prepaid and other current assets | 134,300,000 | 189,400,000 | 183,700,000 | 181,400,000 | 159,000,000 | 173,700,000 | 182,200,000 | 212,200,000 | 156,000,000 | 168,300,000 | 173,800,000 | 195,000,000 | 197,600,000 | 192,600,000 | 151,500,000 | 153,600,000 | 171,700,000 | 81,600,000 | 77,900,000 | 86,500,000 | 79,400,000 | 53,900,000 | 62,600,000 | 62,400,000 | 42,600,000 | 30,000,000 | 30,500,000 | 31,500,000 | 27,000,000 | 16,500,000 | 20,400,000 | 21,700,000 | 19,900,000 | 16,600,000 | 13,300,000 | 15,700,000 | 17,000,000 | 9,200,000 | 9,800,000 | 8,700,000 | 7,500,000 | 6,800,000 | 4,000,000 | 5,000,000 | 3,800,000 | 3,900,000 | 2,800,000 | 4,000,000 | 3,500,000 | 3,400,000 | 2,500,000 | 2,800,000 | 2,200,000 | 2,000,000 | 2,688,000 | 2,527,000 | 2,051,000 | 1,781,000 | 2,457,000 | 3,011,000 | 2,304,000 | 2,690,000 | 1,460,000 | 1,614,000 | 1,436,000 | 2,773,000 | 1,239,000 | 1,819,000 | 1,344,000 | 1,426,000 | 1,382,000 | 1,757,000 | 1,118,000 | 1,614,000 | 1,598,000 | 1,313,907 | 488,015 |
total current assets | 4,331,700,000 | 4,033,300,000 | 5,219,500,000 | 5,030,200,000 | 4,553,800,000 | 4,301,400,000 | 4,262,800,000 | 4,848,400,000 | 4,620,700,000 | 4,425,900,000 | 4,698,400,000 | 5,002,900,000 | 3,767,400,000 | 3,668,800,000 | 3,398,500,000 | 3,808,700,000 | 3,746,600,000 | 3,684,400,000 | 3,656,200,000 | 3,474,200,000 | 3,445,100,000 | 3,424,800,000 | 3,237,100,000 | 3,033,000,000 | 1,995,700,000 | 1,969,400,000 | 1,815,700,000 | 1,744,200,000 | 1,690,800,000 | 1,699,500,000 | 914,100,000 | 836,000,000 | 729,300,000 | 744,700,000 | 692,900,000 | 656,800,000 | 330,500,000 | 280,000,000 | 258,600,000 | 241,000,000 | 227,400,000 | 231,300,000 | 203,700,000 | 170,400,000 | 146,200,000 | 145,900,000 | 123,400,000 | 105,500,000 | 93,600,000 | 93,100,000 | 81,700,000 | 74,200,000 | 71,300,000 | 77,600,000 | 75,571,000 | 83,993,000 | 92,822,000 | 104,410,000 | 115,232,000 | 123,980,000 | 54,432,000 | 66,025,000 | 44,488,000 | 50,443,000 | 59,009,000 | 36,920,000 | 43,376,000 | 54,123,000 | 66,506,000 | 32,058,000 | 29,784,000 | 42,955,000 | 53,847,000 | 67,291,000 | 77,083,000 | 57,355,923 | 51,012,767 |
property and equipment | 1,559,700,000 | 1,559,900,000 | 1,471,300,000 | 1,457,300,000 | 1,364,700,000 | 1,339,900,000 | 1,318,800,000 | 1,183,100,000 | 1,108,600,000 | 1,113,100,000 | 1,078,900,000 | 1,077,600,000 | 1,075,500,000 | 1,055,600,000 | 1,002,500,000 | 942,900,000 | 856,500,000 | 801,800,000 | 742,200,000 | 676,000,000 | 589,900,000 | 515,300,000 | 461,800,000 | 384,300,000 | 346,100,000 | 321,300,000 | 301,000,000 | 253,200,000 | 221,400,000 | 183,100,000 | 169,600,000 | 156,800,000 | 152,400,000 | 145,600,000 | 136,100,000 | 125,000,000 | 123,400,000 | 109,400,000 | 88,400,000 | 77,000,000 | 65,900,000 | 54,700,000 | 46,600,000 | 40,600,000 | 35,700,000 | 31,200,000 | 28,000,000 | 26,000,000 | 22,900,000 | 20,700,000 | 19,700,000 | 19,100,000 | 18,300,000 | 18,900,000 | 18,613,000 | 17,768,000 | 16,206,000 | 15,019,000 | 12,524,000 | 12,016,000 | 11,748,000 | 10,763,000 | 9,240,000 | 7,775,000 | 6,880,000 | 6,422,000 | 6,731,000 | 6,495,000 | 6,403,000 | 6,105,000 | 6,442,000 | 6,543,000 | 6,854,000 | 6,649,000 | 5,058,000 | 6,117,685 | 5,463,491 |
operating lease right-of-use assets | 73,100,000 | 77,400,000 | 54,000,000 | 56,400,000 | 59,100,000 | 62,800,000 | 67,500,000 | 71,200,000 | 68,000,000 | 71,400,000 | 73,400,000 | 76,300,000 | 78,000,000 | 80,000,000 | 73,100,000 | 77,900,000 | 82,300,000 | 88,100,000 | 91,300,000 | 94,800,000 | 98,800,000 | 93,300,000 | 94,300,000 | 71,600,000 | 73,800,000 | 71,500,000 | 34,600,000 | 35,800,000 | 27,700,000 | ||||||||||||||||||||||||||||||||||||||||||||||||
goodwill | 24,200,000 | 24,200,000 | 24,100,000 | 24,100,000 | 23,100,000 | 22,800,000 | 23,800,000 | 23,300,000 | 23,200,000 | 25,200,000 | 25,300,000 | 25,800,000 | 25,700,000 | 25,700,000 | 24,700,000 | 25,600,000 | 26,600,000 | 26,500,000 | 23,900,000 | 19,100,000 | 18,900,000 | 19,300,000 | 19,000,000 | 18,700,000 | 18,600,000 | 18,600,000 | 18,400,000 | 18,700,000 | 18,600,000 | 18,700,000 | 18,400,000 | 11,900,000 | 12,300,000 | 12,100,000 | 12,000,000 | 11,900,000 | 11,400,000 | 11,300,000 | 11,800,000 | 11,800,000 | 3,700,000 | 3,700,000 | 3,700,000 | 3,700,000 | 3,200,000 | 3,200,000 | 3,200,000 | 3,200,000 | 3,200,000 | 3,200,000 | 3,200,000 | 3,200,000 | 3,200,000 | 3,200,000 | 3,162,000 | 3,162,000 | 3,162,000 | ||||||||||||||||||||
intangibles | 62,600,000 | 70,800,000 | 79,000,000 | 87,200,000 | 95,200,000 | 103,400,000 | 106,200,000 | 114,500,000 | 123,300,000 | 134,500,000 | 144,500,000 | 154,200,000 | 163,600,000 | 173,300,000 | 24,400,000 | 28,000,000 | 31,400,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
deferred tax assets | 296,100,000 | 295,600,000 | 375,600,000 | 496,300,000 | 487,300,000 | 481,200,000 | 486,500,000 | 475,800,000 | 460,700,000 | 419,400,000 | 501,300,000 | 417,000,000 | 349,100,000 | 341,200,000 | 342,300,000 | 309,500,000 | 290,800,000 | 220,800,000 | 216,300,000 | 216,400,000 | 216,700,000 | 216,400,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
other assets | 285,900,000 | 278,700,000 | 276,500,000 | 175,500,000 | 168,500,000 | 173,000,000 | 88,200,000 | 82,900,000 | 77,700,000 | 75,000,000 | 74,400,000 | 66,900,000 | 56,600,000 | 47,100,000 | 33,700,000 | 24,800,000 | 22,800,000 | 23,300,000 | 20,400,000 | 21,400,000 | 21,000,000 | 14,200,000 | 13,700,000 | 14,200,000 | 16,000,000 | 14,000,000 | 15,500,000 | 14,700,000 | 12,200,000 | 2,800,000 | 2,800,000 | 1,700,000 | 1,900,000 | 1,900,000 | 1,900,000 | 1,900,000 | 1,500,000 | 1,200,000 | 400,000 | 100,000 | 300,000 | 500,000 | 600,000 | 600,000 | 700,000 | 700,000 | 800,000 | 900,000 | 800,000 | 900,000 | 1,000,000 | 1,100,000 | 98,000 | 98,000 | 123,000 | 107,000 | 98,000 | 98,000 | 100,000 | 101,000 | 102,000 | 183,000 | 236,000 | 1,192,000 | 1,210,000 | 1,275,000 | 1,335,000 | 1,933,000 | 2,010,000 | 2,147,000 | 2,284,000 | 2,405,000 | 3,348,000 | ||||
total assets | 6,633,300,000 | 6,339,900,000 | 7,500,000,000 | 7,327,000,000 | 6,751,700,000 | 6,484,500,000 | 6,353,800,000 | 6,799,200,000 | 6,482,200,000 | 6,264,500,000 | 6,596,200,000 | 6,820,700,000 | 5,515,900,000 | 5,391,700,000 | 4,899,200,000 | 5,217,400,000 | 5,057,000,000 | 4,863,600,000 | 4,775,900,000 | 4,503,800,000 | 4,389,800,000 | 4,290,500,000 | 3,833,200,000 | 3,521,800,000 | 2,447,900,000 | 2,395,000,000 | 2,185,700,000 | 2,065,900,000 | 1,974,000,000 | 1,916,000,000 | 1,114,300,000 | 1,007,500,000 | 896,800,000 | 904,100,000 | 842,900,000 | 795,600,000 | 467,200,000 | 402,800,000 | 361,900,000 | 332,800,000 | 299,400,000 | 292,000,000 | 256,700,000 | 218,400,000 | 189,300,000 | 184,600,000 | 159,400,000 | 139,700,000 | 124,900,000 | 122,500,000 | 110,100,000 | 102,300,000 | 98,800,000 | 106,000,000 | 102,796,000 | 110,522,000 | 117,962,000 | 120,475,000 | 128,793,000 | 136,369,000 | 66,555,000 | 77,164,000 | 54,105,000 | 60,565,000 | 68,314,000 | 46,948,000 | 53,956,000 | 65,101,000 | 77,946,000 | 44,366,000 | 43,075,000 | 57,053,000 | 68,962,000 | 77,259,000 | 85,489,000 | 64,552,608 | 56,726,258 |
liabilities and stockholders’ equity | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
current liabilities: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
accounts payable and accrued liabilities | 2,073,900,000 | 1,944,000,000 | 1,932,400,000 | 1,943,800,000 | 1,690,600,000 | 1,585,100,000 | 1,592,500,000 | 1,569,800,000 | 1,446,600,000 | 1,345,500,000 | 1,373,100,000 | 1,156,500,000 | 965,200,000 | 901,800,000 | 764,200,000 | 688,300,000 | 603,100,000 | 573,000,000 | 598,000,000 | 482,000,000 | 502,600,000 | 481,100,000 | 397,000,000 | 315,900,000 | 267,500,000 | 256,400,000 | 232,400,000 | 196,700,000 | 169,100,000 | 147,100,000 | 135,400,000 | 117,900,000 | 88,000,000 | 87,200,000 | 80,600,000 | 72,200,000 | 65,400,000 | 68,100,000 | 58,600,000 | 49,900,000 | 45,100,000 | 38,900,000 | 34,300,000 | 24,000,000 | 21,200,000 | 20,400,000 | 20,900,000 | 20,000,000 | 15,900,000 | 14,100,000 | 12,600,000 | 9,100,000 | 7,500,000 | 8,700,000 | 10,520,000 | 7,532,000 | 7,980,000 | 6,346,000 | 6,045,000 | 4,965,000 | 4,234,000 | 5,350,000 | 7,075,000 | 5,684,000 | 5,112,000 | 5,745,000 | 4,373,000 | 4,118,000 | 3,774,000 | 4,599,000 | 2,663,000 | 3,736,000 | 3,245,000 | 4,535,000 | 2,088,000 | 2,763,300 | 6,008,194 |
accrued payroll and related expenses | 121,800,000 | 169,200,000 | 170,200,000 | 129,300,000 | 110,800,000 | 112,000,000 | 105,800,000 | 116,100,000 | 110,500,000 | 171,000,000 | 151,300,000 | 108,600,000 | 94,800,000 | 134,300,000 | 112,700,000 | 94,800,000 | 84,700,000 | 125,200,000 | 115,300,000 | 98,100,000 | 81,400,000 | 114,300,000 | 92,100,000 | 67,400,000 | 59,000,000 | 88,500,000 | 70,900,000 | 73,900,000 | 51,300,000 | 72,400,000 | 55,000,000 | 46,100,000 | 34,200,000 | 48,500,000 | 35,300,000 | 31,400,000 | 30,100,000 | 33,400,000 | 27,000,000 | 23,300,000 | 16,700,000 | 24,900,000 | 20,400,000 | 17,000,000 | 12,100,000 | 17,200,000 | 16,800,000 | 13,000,000 | 11,000,000 | 15,100,000 | 12,400,000 | 10,100,000 | 7,200,000 | 9,200,000 | 8,662,000 | 7,930,000 | 6,251,000 | 6,804,000 | 6,961,000 | 6,403,000 | 4,703,000 | 5,730,000 | 5,623,000 | 4,883,000 | 4,048,000 | 4,406,000 | 3,560,000 | 3,158,000 | 2,187,000 | 2,115,000 | 2,722,000 | 2,431,000 | 2,410,000 | 2,537,000 | 2,644,000 | 1,557,578 | 889,362 |
short-term operating lease liabilities | 20,500,000 | 21,600,000 | 23,600,000 | 23,400,000 | 22,600,000 | 22,500,000 | 22,300,000 | 21,600,000 | 20,700,000 | 21,100,000 | 21,000,000 | 21,800,000 | 22,200,000 | 20,500,000 | 20,900,000 | 21,200,000 | 20,900,000 | 20,500,000 | 19,300,000 | 18,800,000 | 18,200,000 | 16,500,000 | 15,800,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
other current liabilities | 7,600,000 | 7,700,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
total current liabilities | 2,223,800,000 | 2,142,500,000 | 3,336,000,000 | 3,308,700,000 | 3,037,100,000 | 2,932,000,000 | 1,734,500,000 | 1,722,200,000 | 1,594,200,000 | 1,556,000,000 | 1,678,600,000 | 2,069,700,000 | 1,865,000,000 | 1,839,300,000 | 900,500,000 | 807,000,000 | 711,400,000 | 720,800,000 | 734,900,000 | 600,700,000 | 604,100,000 | 614,100,000 | 506,400,000 | 400,100,000 | 342,800,000 | 360,200,000 | 322,400,000 | 288,200,000 | 235,400,000 | 222,400,000 | 193,900,000 | 170,800,000 | 125,100,000 | 138,900,000 | 118,200,000 | 105,100,000 | 171,700,000 | 102,400,000 | 86,100,000 | 73,900,000 | 64,100,000 | 66,900,000 | 58,800,000 | 44,200,000 | 37,000,000 | 40,600,000 | 40,600,000 | 35,600,000 | 29,700,000 | 32,100,000 | 27,400,000 | 21,100,000 | 16,200,000 | 19,500,000 | 20,404,000 | 16,961,000 | 16,076,000 | 14,741,000 | 14,743,000 | 13,776,000 | 11,595,000 | 15,129,000 | 17,008,000 | 15,514,000 | 15,828,000 | 18,796,000 | 17,535,000 | 16,624,000 | 14,997,000 | 14,996,000 | 7,827,000 | 8,609,000 | 8,097,000 | 8,447,000 | 6,107,000 | 5,228,678 | 7,074,096 |
long-term senior convertible notes | 1,241,800,000 | 1,240,900,000 | 1,239,900,000 | 1,238,900,000 | 1,238,000,000 | 1,237,000,000 | 2,439,600,000 | 2,437,800,000 | 2,436,000,000 | 2,434,200,000 | 2,432,400,000 | 2,430,600,000 | 1,198,500,000 | 1,197,700,000 | 1,968,800,000 | 1,967,300,000 | 1,965,900,000 | 1,702,700,000 | 1,703,500,000 | 1,710,700,000 | 1,688,800,000 | 1,667,200,000 | 1,645,800,000 | 1,658,800,000 | 1,072,400,000 | 1,059,700,000 | 1,047,100,000 | 1,034,700,000 | 1,022,400,000 | 1,010,300,000 | |||||||||||||||||||||||||||||||||||||||||||||||
long-term operating lease liabilities | 69,000,000 | 73,400,000 | 50,600,000 | 54,700,000 | 59,700,000 | 65,000,000 | 71,100,000 | 76,800,000 | 75,800,000 | 80,100,000 | 83,400,000 | 86,900,000 | 89,700,000 | 94,600,000 | 82,100,000 | 87,700,000 | 93,300,000 | 98,600,000 | 102,900,000 | 107,100,000 | 111,300,000 | 101,800,000 | 103,200,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
other long-term liabilities | 141,800,000 | 137,100,000 | 147,400,000 | 151,600,000 | 150,300,000 | 147,900,000 | 129,600,000 | 128,100,000 | 129,400,000 | 125,600,000 | 133,900,000 | 133,100,000 | 129,700,000 | 128,300,000 | 123,300,000 | 99,500,000 | 97,100,000 | 90,000,000 | 98,500,000 | 87,700,000 | 82,400,000 | 80,900,000 | 78,500,000 | 35,300,000 | 20,900,000 | 20,100,000 | 17,600,000 | 17,500,000 | 18,100,000 | 683,000 | |||||||||||||||||||||||||||||||||||||||||||||||
total liabilities | 3,676,400,000 | 3,593,900,000 | 4,773,900,000 | 4,753,900,000 | 4,485,100,000 | 4,381,900,000 | 4,374,800,000 | 4,364,900,000 | 4,235,400,000 | 4,195,900,000 | 4,328,300,000 | 4,720,300,000 | 3,282,900,000 | 3,259,900,000 | 3,074,700,000 | 2,961,500,000 | 2,867,700,000 | 2,612,100,000 | 2,639,800,000 | 2,506,200,000 | 2,486,600,000 | 2,464,000,000 | 2,333,900,000 | 2,167,900,000 | 1,513,400,000 | 1,512,400,000 | 1,421,400,000 | 1,377,600,000 | 1,305,400,000 | 1,252,700,000 | 552,100,000 | 525,400,000 | 475,100,000 | 484,700,000 | 458,900,000 | 441,900,000 | 189,400,000 | 119,000,000 | 100,100,000 | 86,400,000 | 68,200,000 | 70,800,000 | 63,400,000 | 47,700,000 | 40,700,000 | 44,400,000 | 44,400,000 | 40,100,000 | 34,900,000 | 38,400,000 | 35,400,000 | 30,000,000 | 25,200,000 | 29,000,000 | 22,543,000 | 19,214,000 | 18,411,000 | 15,985,000 | 15,728,000 | 14,794,000 | 13,193,000 | 16,171,000 | 18,861,000 | 19,547,000 | 21,587,000 | 65,393,000 | 63,057,000 | 63,124,000 | 62,792,000 | 82,979,000 | 70,368,000 | 71,761,000 | 71,854,000 | ||||
commitments and contingencies | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
stockholders’ equity: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
preferred stock, 0.001 par value... | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
common stock, 0.001 par value... | 400,000 | 400,000 | 400,000 | 400,000 | 400,000 | 400,000 | 400,000 | 400,000 | 400,000 | 400,000 | 400,000 | 400,000 | 400,000 | 400,000 | 400,000 | 400,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 70,000 | 69,000 | 69,000 | 68,000 | 68,000 | 63,000 | 60,000 | 58,000 | 58,000 | 46,000 | 46,000 | 46,000 | 30,000 | 30,000 | 30,000 | 29,000 | 28,000 | 28,164 | 25,417 | |||||
additional paid-in capital | 2,337,500,000 | 2,281,500,000 | 2,246,500,000 | 2,187,500,000 | 2,142,200,000 | 2,093,800,000 | 2,050,500,000 | 1,992,300,000 | 2,510,600,000 | 3,514,600,000 | 3,618,000,000 | 2,269,000,000 | 2,305,600,000 | 2,258,100,000 | 2,072,100,000 | 2,028,900,000 | 1,996,600,000 | 2,504,500,000 | 2,322,100,000 | 2,193,600,000 | 2,162,000,000 | 2,125,300,000 | 2,153,700,000 | 2,079,800,000 | 1,706,500,000 | 1,675,900,000 | 1,651,600,000 | 1,620,400,000 | 1,590,600,000 | 1,560,600,000 | 1,181,600,000 | 1,149,100,000 | 1,122,500,000 | 1,093,700,000 | 1,048,500,000 | 1,015,600,000 | 942,300,000 | 905,700,000 | 876,000,000 | 841,800,000 | 806,000,000 | 776,800,000 | 750,400,000 | 685,300,000 | 659,500,000 | 638,000,000 | 614,100,000 | 593,600,000 | 577,900,000 | 559,500,000 | 547,500,000 | 539,100,000 | 530,300,000 | 522,600,000 | 517,418,000 | 511,206,000 | 504,773,000 | 495,626,000 | 491,964,000 | 487,203,000 | 411,610,000 | 407,375,000 | 371,789,000 | 364,133,000 | 358,190,000 | 272,730,000 | 270,496,000 | 268,024,000 | 265,921,000 | 192,743,000 | 190,744,000 | 188,605,000 | 186,249,000 | 183,325,000 | 181,285,000 | 187,162,062 | 134,257,379 |
accumulated other comprehensive income | 106,200,000 | 115,000,000 | 81,500,000 | 83,600,000 | 2,200,000 | 63,400,000 | -11,600,000 | -41,100,000 | -23,000,000 | -6,100,000 | 500,000 | 1,400,000 | 2,800,000 | 2,900,000 | 3,200,000 | 2,800,000 | 3,500,000 | 3,700,000 | 2,300,000 | 1,000,000 | 2,000,000 | 1,600,000 | 1,500,000 | -13,000 | 36,000 | 63,000 | 13,000 | 50,000 | -81,000 | -45,000 | 53,000 | 13,000 | 34,000 | 11,923 | |||||||||||||||||||||||||||||||||||||||||||
retained earnings | 2,633,400,000 | 2,433,900,000 | 2,166,600,000 | 1,882,800,000 | 1,703,000,000 | 1,597,600,000 | 1,445,900,000 | 1,311,300,000 | 1,167,800,000 | 1,021,400,000 | 765,100,000 | 644,400,000 | 528,500,000 | 479,900,000 | 388,100,000 | 286,900,000 | 236,000,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
treasury stock | -2,120,600,000 | -2,084,800,000 | -1,768,900,000 | -1,581,200,000 | -1,581,200,000 | -1,581,200,000 | -1,581,200,000 | -831,700,000 | -1,394,700,000 | -2,451,100,000 | -2,080,000,000 | -784,100,000 | -595,000,000 | -595,000,000 | -595,000,000 | -37,300,000 | -37,300,000 | -206,200,000 | -159,500,000 | -100,000,000 | -100,000,000 | -100,000,000 | -100,000,000 | -100,000,000 | -100,000,000 | -100,000,000 | -100,000,000 | -100,000,000 | -100,000,000 | -100,000,000 | |||||||||||||||||||||||||||||||||||||||||||||||
total stockholders’ equity | 2,956,900,000 | 2,746,000,000 | 2,726,100,000 | 2,573,100,000 | 2,266,600,000 | 2,102,600,000 | 1,979,000,000 | 2,434,300,000 | 2,246,800,000 | 2,068,600,000 | 2,267,900,000 | 2,100,400,000 | 2,233,000,000 | 2,131,800,000 | 1,824,500,000 | 2,255,900,000 | 2,189,300,000 | 2,251,500,000 | 2,136,100,000 | 1,997,600,000 | 1,903,200,000 | 1,826,500,000 | 1,499,300,000 | 1,353,900,000 | 934,500,000 | 882,600,000 | 764,300,000 | 688,300,000 | 668,600,000 | 663,300,000 | 562,200,000 | 482,100,000 | 421,700,000 | 419,400,000 | 384,000,000 | 353,700,000 | 277,800,000 | 283,800,000 | 261,800,000 | 246,400,000 | 231,200,000 | 221,200,000 | 193,300,000 | 170,700,000 | 148,600,000 | 140,200,000 | 115,000,000 | 99,600,000 | 90,000,000 | 84,100,000 | 74,700,000 | 72,300,000 | 73,600,000 | 77,000,000 | 80,253,000 | 91,308,000 | 99,551,000 | 104,490,000 | 113,065,000 | 121,575,000 | 53,362,000 | 60,993,000 | 35,244,000 | 41,018,000 | 46,727,000 | 1,977,000 | 15,154,000 | 7,115,000 | 17,324,000 | 56,828,267 | 49,412,063 | ||||||
total liabilities and stockholders’ equity | 6,633,300,000 | 6,339,900,000 | 7,500,000,000 | 7,327,000,000 | 6,751,700,000 | 6,484,500,000 | 6,353,800,000 | 6,799,200,000 | 6,482,200,000 | 6,264,500,000 | 6,596,200,000 | 6,820,700,000 | 5,515,900,000 | 5,391,700,000 | 4,899,200,000 | 5,217,400,000 | 5,057,000,000 | 4,863,600,000 | 4,775,900,000 | 4,503,800,000 | 4,389,800,000 | 4,290,500,000 | 3,833,200,000 | 3,521,800,000 | 2,447,900,000 | 2,395,000,000 | 2,185,700,000 | 2,065,900,000 | 1,974,000,000 | 1,916,000,000 | 1,114,300,000 | 1,007,500,000 | 896,800,000 | 904,100,000 | 842,900,000 | 795,600,000 | 467,200,000 | 402,800,000 | 361,900,000 | 332,800,000 | 299,400,000 | 292,000,000 | 256,700,000 | 218,400,000 | 189,300,000 | 184,600,000 | 159,400,000 | 139,700,000 | 124,900,000 | 122,500,000 | 110,100,000 | 102,300,000 | 98,800,000 | 106,000,000 | 102,796,000 | 110,522,000 | 117,962,000 | 120,475,000 | 128,793,000 | 136,369,000 | 66,555,000 | 77,164,000 | 54,105,000 | 60,565,000 | 68,314,000 | 65,101,000 | 77,946,000 | 57,053,000 | 68,962,000 | 77,259,000 | 85,489,000 | 64,552,608 | |||||
current portion of long-term senior convertible notes | 1,206,900,000 | 1,206,100,000 | 1,205,300,000 | 1,204,400,000 | 124,200,000 | 773,800,000 | 773,200,000 | 772,600,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
deferred revenue | 2,900,000 | 6,100,000 | 7,800,000 | 8,000,000 | 13,900,000 | 14,700,000 | 16,400,000 | 18,400,000 | 9,000,000 | 9,000,000 | 9,600,000 | 10,100,000 | 2,700,000 | 2,700,000 | 2,700,000 | 2,100,000 | 2,300,000 | 1,800,000 | 1,900,000 | 2,200,000 | 1,500,000 | 1,700,000 | 1,800,000 | 1,700,000 | 4,300,000 | 3,500,000 | 2,700,000 | 2,900,000 | 3,500,000 | 6,800,000 | 2,900,000 | 3,200,000 | |||||||||||||||||||||||||||||||||||||||||||||
accumulated other comprehensive loss | -8,000,000 | -38,000,000 | -37,300,000 | -16,700,000 | -35,600,000 | -29,300,000 | -6,500,000 | -300,000 | -1,300,000 | -4,900,000 | -2,600,000 | -2,200,000 | -1,600,000 | -1,300,000 | -1,000,000 | -700,000 | -700,000 | -300,000 | -300,000 | -300,000 | -300,000 | -300,000 | -100,000 | -100,000 | -200,000 | -100,000 | -100,000 | -100,000 | -100,000 | -100,000 | -100,000 | -93,000 | -88,000 | -103,000 | -80,000 | -94,000 | -101,000 | -83,000 | -66,000 | -39,000 | -5,000 | -40,000 | |||||||||||||||||||||||||||||||||||
* we adjusted our 2021 amounts to reflect the simplified convertible instruments accounting guidance, which we adopted on a full retrospective basis. all periods presented have also been adjusted to reflect the four-for-one stock split. refer to note 1, “organization and significant accounting policies,” to the consolidated financial statements for further information. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
* we adjusted our 2021 amounts to reflect the simplified convertible instruments accounting guidance, which we adopted on a full retrospective basis. all periods presented have also been adjusted to reflect the four-for-one stock split. refer to note 1, “organization and significant accounting policies,” for further information. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
* we adjusted our 2021 amounts to reflect the simplified convertible instruments accounting guidance, which we adopted on a full retrospective basis. refer to note 1 “organization and significant accounting policies” for further information. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
intangibles and other assets | 42,000,000 | 46,000,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
accumulated deficit | -47,400,000 | -28,000,000 | -98,900,000 | -161,800,000 | -202,100,000 | -557,300,000 | -629,500,000 | -675,800,000 | -695,700,000 | -788,400,000 | -834,200,000 | -823,700,000 | -798,900,000 | -619,200,000 | -665,800,000 | -696,000,000 | -671,800,000 | -662,400,000 | -660,400,000 | -663,300,000 | -621,000,000 | -613,600,000 | -594,800,000 | -574,600,000 | -555,400,000 | -556,900,000 | -514,400,000 | -510,700,000 | -497,800,000 | -499,100,000 | -493,900,000 | -487,900,000 | -475,400,000 | -472,800,000 | -466,800,000 | -456,700,000 | -445,600,000 | -437,142,000 | -419,879,000 | -405,188,000 | -391,124,000 | -378,873,000 | -365,595,000 | -358,228,000 | -346,378,000 | -336,566,000 | -323,168,000 | -311,481,000 | -291,208,000 | -279,679,000 | -266,156,000 | -250,826,000 | -231,436,000 | -217,986,000 | -203,298,000 | -189,224,000 | -176,252,000 | ||||||||||||||||||||
operating lease liabilities, current portion | 15,100,000 | 14,500,000 | 13,600,000 | 14,800,000 | 14,100,000 | 12,300,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
operating lease liabilities, net of current portion | 73,700,000 | 77,300,000 | 72,400,000 | 34,300,000 | 37,200,000 | 29,500,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
other liabilities | 20,000,000 | 19,400,000 | 19,600,000 | 18,700,000 | 18,200,000 | 16,700,000 | 16,300,000 | 17,700,000 | 16,600,000 | 14,000,000 | 12,500,000 | 4,100,000 | 3,900,000 | 4,200,000 | 2,400,000 | 2,000,000 | 1,500,000 | 900,000 | 1,000,000 | 1,100,000 | 1,700,000 | 2,800,000 | 3,100,000 | 2,700,000 | 2,100,000 | 1,570,000 | 1,551,000 | 1,501,000 | 963,000 | 985,000 | 1,018,000 | 1,027,000 | 1,042,000 | 972,000 | 750,000 | 791,000 | 840,000 | 839,000 | 880,000 | 916,000 | 889,000 | 679,000 | 679,000 | 673,000 | 666,000 | ||||||||||||||||||||||||||||||||
long term senior convertible notes | 338,800,000 | 335,000,000 | 331,300,000 | 327,600,000 | 324,000,000 | 320,500,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
short-term marketable securities, available-for-sale | 107,100,000 | 123,700,000 | 100,700,000 | 27,600,000 | 29,200,000 | 29,600,000 | 28,100,000 | 28,600,000 | 29,100,000 | 28,000,000 | 29,800,000 | 29,600,000 | 11,800,000 | 11,700,000 | 11,800,000 | 11,700,000 | 11,400,000 | 14,200,000 | 18,200,000 | 26,400,000 | 40,600,000 | 48,641,000 | 55,203,000 | 65,065,000 | 79,358,000 | 79,794,000 | 71,139,000 | 33,526,000 | 42,224,000 | 24,380,000 | 33,991,000 | 39,221,000 | 24,439,000 | 31,356,000 | 44,666,000 | 52,176,000 | 14,368,000 | 20,741,000 | 32,896,000 | 26,632,000 | 41,208,000 | 59,103,000 | 36,341,449 | 13,277,688 | |||||||||||||||||||||||||||||||||
current portion of deferred revenue | 2,300,000 | 1,500,000 | 1,200,000 | 900,000 | 500,000 | 700,000 | 600,000 | 800,000 | 1,600,000 | 800,000 | 1,300,000 | 700,000 | 600,000 | 300,000 | 600,000 | 700,000 | 600,000 | 700,000 | 800,000 | 1,400,000 | 1,222,000 | 1,499,000 | 1,845,000 | 1,591,000 | 1,737,000 | 2,333,000 | 2,358,000 | 3,524,000 | 3,560,000 | 4,047,000 | 5,768,000 | 7,745,000 | 8,702,000 | 8,104,000 | 7,448,000 | 6,351,000 | 167,000 | 167,000 | 167,000 | ||||||||||||||||||||||||||||||||||||||
short-term borrowings | 75,000,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
intangible assets | 200,000 | 1,600,000 | 1,800,000 | 2,000,000 | 2,200,000 | 2,400,000 | 2,500,000 | 2,600,000 | 2,700,000 | 3,100,000 | 3,300,000 | 3,400,000 | 3,600,000 | 3,700,000 | 3,900,000 | 4,000,000 | 4,200,000 | 4,313,000 | 4,462,000 | 4,610,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
current portion of long-term debt | 1,700,000 | 2,300,000 | 2,500,000 | 2,400,000 | 2,400,000 | 2,300,000 | 2,300,000 | 2,300,000 | 2,200,000 | 2,200,000 | 1,800,000 | 1,200,000 | 700,000 | 200,000 | 75,000 | 300,000 | 525,000 | 750,000 | 900,000 | 900,000 | 900,000 | 900,000 | 1,244,000 | 1,588,000 | 1,931,000 | 2,275,000 | 2,275,000 | 2,275,000 | 1,375,000 | 1,375,000 | 907,800 | ||||||||||||||||||||||||||||||||||||||||||||||
restricted cash | 700,000 | 1,000,000 | 1,000,000 | 1,000,000 | 1,000,000 | 1,000,000 | 1,000,000 | 1,000,000 | 1,000,000 | 1,000,000 | 1,000,000 | 1,039,000 | 1,039,000 | 1,039,000 | 939,000 | 939,000 | 989,000 | 1,214,000 | 1,439,000 | 1,664,000 | 2,164,000 | 2,189,000 | 2,414,000 | 2,639,000 | 3,208,000 | 3,702,000 | 4,270,000 | 4,839,000 | 5,408,000 | 5,977,000 | 914,000 | 1,079,000 | 250,000 | ||||||||||||||||||||||||||||||||||||||||||||
long-term debt | 400,000 | 1,100,000 | 1,700,000 | 2,300,000 | 2,900,000 | 3,500,000 | 4,100,000 | 4,600,000 | 5,200,000 | 5,800,000 | 6,300,000 | 6,800,000 | 3,283,000 | 4,968,000 | 45,757,000 | 44,683,000 | 43,667,000 | 42,706,000 | 61,425,000 | 61,650,000 | 62,219,000 | 62,788,000 | 61,031,000 | 61,375,000 | 2,118,200 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
long-term portion of deferred revenue | 600,000 | 569,000 | 702,000 | 834,000 | 281,000 | 571,000 | 881,000 | 1,953,000 | 4,173,000 | 5,669,000 | 212,000 | 254,000 | 296,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
preferred stock, 0.001 par value per share... | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
common stock, 0.001 par value per share... | 100,000 | 68,000 | 62,000 | 46,000 | 30,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
stockholders’ equity | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
stockholders’ deficit: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
total stockholders’ deficit | -18,445,000 | -9,101,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
total liabilities and stockholders’ deficit | 46,948,000 | 53,956,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
stockholders’ (deficit) equity: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
total stockholders’ (deficit) equity | -38,613,000 | -27,293,000 | -14,708,000 | -2,892,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
total liabilities and stockholders’ (deficit) equity | 44,366,000 | 43,075,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
deferred rent | 377,463 | 240,099 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
deferred stock-based compensation | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
deferred offering costs and other assets | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
liabilities, redeemable convertible preferred stock and stockholders’ equity | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
accrued clinical trials | 176,540 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
redeemable convertible series b preferred stock, 0.001 par value... | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
redeemable convertible series c preferred stock, 0.001 par value... | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
redeemable convertible series d preferred stock, 0.001 par value... | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
convertible series a preferred stock, 0.001 par value... | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
deficit accumulated during the development stage | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
total liabilities, redeemable convertible preferred stock and stockholders’ equity | 56,726,258 |
Cashflow Statements:
Quarterly
Annual
| Unit: USD | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | 2017-09-30 | 2017-06-30 | 2017-03-31 | 2016-12-31 | 2016-09-30 | 2016-06-30 | 2016-03-31 | 2015-12-31 | 2015-09-30 | 2015-06-30 | 2015-03-31 | 2014-09-30 | 2014-06-30 | 2014-03-31 | 2013-12-31 | 2013-09-30 | 2013-06-30 | 2013-03-31 | 2012-12-31 | 2012-09-30 | 2012-06-30 | 2012-03-31 | 2011-12-31 | 2011-09-30 | 2011-06-30 | 2011-03-31 | 2010-12-31 | 2010-09-30 | 2010-06-30 | 2010-03-31 | 2009-12-31 | 2009-09-30 | 2009-06-30 | 2009-03-31 | 2008-12-31 | 2008-09-30 | 2008-06-30 | 2008-03-31 | 2007-12-31 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
operating activities | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
net income | 199,500,000 | 267,300,000 | 283,800,000 | 179,800,000 | 105,400,000 | 151,700,000 | 134,600,000 | 143,500,000 | 146,400,000 | 256,300,000 | 120,700,000 | 115,900,000 | 48,600,000 | 91,800,000 | 101,200,000 | 50,900,000 | 97,300,000 | -19,400,000 | 70,900,000 | 62,900,000 | 40,300,000 | 355,200,000 | 72,200,000 | 46,300,000 | 19,900,000 | 92,700,000 | 45,800,000 | -10,500,000 | -26,900,000 | -179,700,000 | 46,600,000 | 30,200,000 | -24,200,000 | -2,000,000 | 2,900,000 | -41,700,000 | -7,400,000 | -18,800,000 | -20,200,000 | -19,200,000 | 1,500,000 | -42,500,000 | -3,700,000 | -12,900,000 | -5,200,000 | -6,000,000 | -12,500,000 | -2,600,000 | -6,000,000 | -10,100,000 | -11,100,000 | -8,482,000 | -17,263,000 | -14,691,000 | -14,064,000 | -12,251,000 | -13,278,000 | -7,367,000 | -11,850,000 | -9,812,000 | -13,398,000 | -11,687,000 | -20,273,000 | -11,529,000 | -13,523,000 | -15,330,000 | -13,142,000 | -13,450,000 | -14,688,000 | -14,074,000 | -12,972,000 | -12,229,000 |
adjustments to reconcile net income to cash from operating activities: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
depreciation and amortization | 67,100,000 | 65,200,000 | 63,600,000 | 63,000,000 | 60,000,000 | 57,800,000 | 55,300,000 | 52,100,000 | 52,500,000 | 52,500,000 | 48,200,000 | 43,700,000 | 41,600,000 | 36,300,000 | 39,200,000 | 43,600,000 | 36,800,000 | 32,100,000 | 25,500,000 | 23,500,000 | 20,900,000 | 20,400,000 | 18,400,000 | 15,300,000 | 13,000,000 | 14,300,000 | 12,900,000 | 11,600,000 | 9,900,000 | 8,600,000 | 7,800,000 | 6,700,000 | 6,000,000 | 4,300,000 | 3,900,000 | 3,700,000 | 3,600,000 | 4,100,000 | 3,900,000 | 3,400,000 | 3,100,000 | 2,700,000 | 2,600,000 | 2,400,000 | 2,200,000 | 1,900,000 | 1,900,000 | 1,900,000 | 1,700,000 | 1,600,000 | 1,800,000 | 1,751,000 | 2,199,000 | 1,468,000 | 1,182,000 | 1,063,000 | 998,000 | 892,000 | 806,000 | 721,000 | 628,000 | 588,000 | 500,000 | 470,000 | 589,000 | 662,000 | 652,000 | 768,000 | 710,000 | 703,000 | 855,000 | 1,004,000 |
share-based compensation | 43,300,000 | 35,000,000 | 45,100,000 | 45,300,000 | 34,200,000 | 43,300,000 | 43,400,000 | 44,700,000 | 39,000,000 | 36,900,000 | 39,000,000 | 39,700,000 | 35,200,000 | 34,000,000 | 30,800,000 | 32,600,000 | 29,100,000 | 26,300,000 | 27,500,000 | 31,600,000 | 28,000,000 | 34,100,000 | 30,700,000 | 30,700,000 | 23,900,000 | 23,600,000 | 24,400,000 | 29,700,000 | 25,000,000 | 24,600,000 | 27,100,000 | 25,600,000 | 24,600,000 | 25,400,000 | 25,300,000 | 30,600,000 | 29,100,000 | 29,000,000 | 27,600,000 | 25,100,000 | 23,500,000 | 22,600,000 | 20,700,000 | 15,900,000 | 13,800,000 | 13,200,000 | 8,700,000 | 6,600,000 | 6,600,000 | 6,400,000 | 5,000,000 | 4,542,000 | 4,879,000 | 4,833,000 | 4,146,000 | 3,580,000 | 3,728,000 | 3,657,000 | 2,548,000 | 2,078,000 | 2,317,000 | 2,771,000 | 2,275,000 | 2,154,000 | 2,130,000 | 2,041,000 | 2,041,000 | 1,787,000 | 1,972,000 | 1,948,000 | ||
non-cash interest expense | 1,000,000 | 1,700,000 | 1,900,000 | 1,800,000 | 1,900,000 | 1,900,000 | 1,900,000 | 1,800,000 | 1,900,000 | 2,000,000 | 2,200,000 | 2,100,000 | 1,500,000 | 1,600,000 | 1,500,000 | 1,600,000 | 1,600,000 | 22,000,000 | 22,000,000 | 22,500,000 | 22,200,000 | 22,000,000 | 21,700,000 | 17,600,000 | 12,700,000 | 12,600,000 | 12,500,000 | 12,300,000 | 12,200,000 | 6,600,000 | 3,800,000 | 3,800,000 | 3,700,000 | 3,600,000 | ||||||||||||||||||||||||||||||||||||||
deferred income taxes | 300,000 | 78,900,000 | 118,000,000 | -8,900,000 | -5,800,000 | 24,300,000 | -11,600,000 | -14,700,000 | -41,800,000 | 81,500,000 | -85,000,000 | -42,200,000 | -9,300,000 | 32,000,000 | -33,800,000 | -19,900,000 | 100,000 | -5,100,000 | 100,000 | 400,000 | -300,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||
net losses on equity investments | 0 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
other non-cash income and expenses | -3,100,000 | -6,000,000 | -400,000 | -12,300,000 | 16,000,000 | -39,900,000 | -15,600,000 | -7,800,000 | -36,600,000 | -17,900,000 | -15,700,000 | -13,700,000 | 2,800,000 | 15,900,000 | 12,200,000 | 3,800,000 | 13,100,000 | 14,500,000 | 8,000,000 | 8,000,000 | 9,600,000 | 600,000 | 3,400,000 | 100,000 | 1,500,000 | 2,500,000 | -2,200,000 | 300,000 | -300,000 | 300,000 | 5,600,000 | -900,000 | ||||||||||||||||||||||||||||||||||||||||
changes in operating assets and liabilities: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
accounts receivable | 124,600,000 | -106,200,000 | 237,800,000 | -184,600,000 | -148,900,000 | -7,400,000 | -55,600,000 | 33,800,000 | -5,800,000 | -187,200,000 | -35,800,000 | -113,700,000 | 76,600,000 | -148,300,000 | -4,500,000 | -17,000,000 | -30,100,000 | 15,100,000 | -35,700,000 | -40,000,000 | -14,900,000 | -58,500,000 | -73,400,000 | 4,300,000 | -14,700,000 | -50,800,000 | -18,400,000 | -12,300,000 | 21,500,000 | -57,000,000 | -8,100,000 | -38,800,000 | 10,700,000 | -8,700,000 | -15,300,000 | 15,800,000 | -25,000,000 | -3,000,000 | -6,000,000 | 6,800,000 | -18,300,000 | -10,300,000 | -5,300,000 | 2,200,000 | -2,800,000 | -4,700,000 | 2,200,000 | -4,500,000 | -3,800,000 | -1,400,000 | 3,200,000 | -7,190,000 | 543,000 | -357,000 | 4,000 | -3,544,000 | -309,000 | -1,536,000 | -487,000 | -1,569,000 | -441,000 | -860,000 | -311,000 | -1,003,000 | -420,000 | -722,000 | -227,000 | -689,000 | 139,000 | -247,000 | -106,000 | |
inventory | -65,200,000 | -17,800,000 | -33,600,000 | -18,500,000 | 6,200,000 | 32,700,000 | -1,900,000 | 18,300,000 | -36,700,000 | -59,000,000 | -78,600,000 | -55,400,000 | -59,600,000 | 5,700,000 | 26,900,000 | 1,100,000 | 15,600,000 | -6,000,000 | -21,700,000 | -29,500,000 | -55,000,000 | -33,600,000 | -35,400,000 | -23,300,000 | -22,200,000 | 600,000 | -2,500,000 | -16,800,000 | -30,400,000 | -15,500,000 | -9,000,000 | 5,400,000 | -6,400,000 | -600,000 | 3,800,000 | -1,000,000 | -900,000 | -1,700,000 | 3,700,000 | -10,900,000 | -4,600,000 | -8,200,000 | -4,000,000 | -2,400,000 | -2,700,000 | -2,800,000 | 200,000 | 900,000 | -2,700,000 | 300,000 | -100,000 | -330,000 | 237,000 | 666,000 | 127,000 | -1,716,000 | -197,000 | 167,000 | 1,687,000 | -1,759,000 | -2,266,000 | -236,000 | -1,210,000 | -709,000 | -569,000 | 1,002,000 | 81,000 | 144,000 | 181,000 | -947,000 | -685,000 | -104,000 |
prepaid and other assets | 51,000,000 | -6,900,000 | -2,400,000 | -22,000,000 | 16,500,000 | 8,000,000 | 31,600,000 | -56,800,000 | 11,400,000 | 6,100,000 | 16,600,000 | 10,000,000 | -13,400,000 | -50,400,000 | 1,300,000 | 15,400,000 | -97,900,000 | -3,100,000 | 8,900,000 | -6,900,000 | -20,200,000 | 9,400,000 | 14,800,000 | -19,000,000 | -7,600,000 | -4,600,000 | 800,000 | 2,000,000 | -5,400,000 | 400,000 | 1,600,000 | -2,300,000 | -2,700,000 | 2,500,000 | 1,500,000 | -7,700,000 | 200,000 | -1,400,000 | -1,700,000 | -1,000,000 | -1,200,000 | 200,000 | 1,300,000 | -900,000 | 300,000 | -700,000 | -100,000 | -18,000 | -139,000 | -412,000 | -231,000 | 720,000 | 689,000 | -560,000 | 389,000 | -1,133,000 | 162,000 | -136,000 | 2,395,000 | -1,539,000 | 696,000 | -563,000 | 402,000 | -133,000 | 337,000 | -478,000 | 422,000 | -36,000 | ||||
operating lease right-of-use assets and liabilities | -1,300,000 | -2,600,000 | -1,500,000 | -2,100,000 | -900,000 | -3,500,000 | 600,000 | -1,600,000 | -2,000,000 | -100,000 | -2,300,000 | -1,400,000 | -700,000 | 300,000 | -2,700,000 | -2,500,000 | -900,000 | 0 | -1,200,000 | 400,000 | 700,000 | 500,000 | -100,000 | -800,000 | -400,000 | |||||||||||||||||||||||||||||||||||||||||||||||
accounts payable and accrued liabilities | 145,100,000 | -10,100,000 | -2,300,000 | 234,000,000 | 125,400,000 | -20,000,000 | 49,800,000 | 72,300,000 | 109,600,000 | -30,000,000 | 219,500,000 | 190,300,000 | 86,700,000 | 123,800,000 | 75,300,000 | 42,500,000 | 53,500,000 | -57,300,000 | 30,000,000 | 67,900,000 | 69,800,000 | 51,500,000 | 5,300,000 | 30,800,000 | 24,300,000 | 28,400,000 | 25,500,000 | 6,000,000 | 17,300,000 | 30,700,000 | 2,200,000 | 10,700,000 | -300,000 | 2,100,000 | 2,500,000 | 9,300,000 | 5,600,000 | 3,700,000 | 5,000,000 | 9,100,000 | 2,100,000 | 1,600,000 | 1,700,000 | 4,500,000 | -100,000 | -500,000 | 2,100,000 | 1,300,000 | -500,000 | -2,066,000 | 2,817,000 | 180,000 | -631,000 | 301,000 | 1,080,000 | 731,000 | -1,116,000 | -1,728,000 | 1,387,000 | 572,000 | -663,000 | 1,372,000 | 255,000 | 344,000 | -463,000 | 1,581,000 | -1,060,000 | 491,000 | -1,303,000 | |||
accrued payroll and related expenses | -47,100,000 | -1,200,000 | 41,300,000 | 15,900,000 | -600,000 | 4,300,000 | -9,100,000 | 5,500,000 | -60,700,000 | 20,600,000 | 42,100,000 | 13,800,000 | -39,300,000 | 22,500,000 | 17,100,000 | 9,400,000 | -40,500,000 | 9,900,000 | 16,700,000 | 16,800,000 | -33,000,000 | 21,800,000 | 25,100,000 | 8,300,000 | -29,100,000 | 17,200,000 | -2,800,000 | 22,700,000 | -21,100,000 | 17,600,000 | 8,200,000 | 12,400,000 | -14,400,000 | 3,700,000 | 1,200,000 | -3,300,000 | 6,500,000 | 3,700,000 | 6,500,000 | -8,200,000 | 4,600,000 | 3,300,000 | 4,900,000 | -5,100,000 | 3,700,000 | 2,000,000 | -4,000,000 | 2,700,000 | 2,300,000 | 2,800,000 | -2,000,000 | 542,000 | 732,000 | 1,679,000 | -553,000 | -157,000 | 558,000 | 1,700,000 | -1,027,000 | 107,000 | 740,000 | 835,000 | -358,000 | 846,000 | 402,000 | 971,000 | 72,000 | -607,000 | 291,000 | 21,000 | -127,000 | -107,000 |
deferred revenue and other liabilities | 7,300,000 | -6,200,000 | -7,700,000 | -300,000 | 2,700,000 | -7,700,000 | 400,000 | -3,900,000 | 3,200,000 | -8,500,000 | 1,500,000 | 3,200,000 | 1,200,000 | -19,600,000 | 25,000,000 | 2,900,000 | 2,800,000 | 2,000,000 | 3,700,000 | 1,900,000 | 1,100,000 | 1,900,000 | 1,300,000 | 14,400,000 | 1,000,000 | -5,000,000 | ||||||||||||||||||||||||||||||||||||||||||||||
net cash from operating activities | 525,600,000 | 294,000,000 | 659,900,000 | 303,000,000 | 183,800,000 | 301,400,000 | 199,500,000 | 279,400,000 | 209,200,000 | 133,600,000 | 269,200,000 | 190,300,000 | 155,400,000 | 132,500,000 | 293,200,000 | 172,800,000 | 71,000,000 | 105,800,000 | 247,300,000 | 61,600,000 | 27,800,000 | 172,000,000 | 147,600,000 | 154,100,000 | 1,900,000 | 143,700,000 | 94,500,000 | 64,500,000 | 11,800,000 | 33,700,000 | 56,800,000 | 41,400,000 | -8,700,000 | 36,200,000 | 14,300,000 | 300,000 | 13,300,000 | 23,000,000 | 20,100,000 | -200,000 | 11,300,000 | 17,900,000 | 16,400,000 | 3,400,000 | 11,400,000 | 6,200,000 | -2,400,000 | 4,400,000 | 1,600,000 | 900,000 | -4,500,000 | -10,557,000 | -6,050,000 | -6,329,000 | -10,164,000 | -11,570,000 | -6,741,000 | -2,526,000 | -9,289,000 | -13,464,000 | -9,470,000 | -9,305,000 | -10,437,000 | -9,173,000 | -9,808,000 | -11,036,000 | -9,372,000 | 2,526,000 | -11,617,000 | -11,901,000 | -16,459,000 | |
capital expenditures | -26,200,000 | -101,900,000 | -85,800,000 | -100,000,000 | -29,400,000 | -124,600,000 | -124,300,000 | -16,100,000 | -16,200,000 | -52,500,000 | -56,800,000 | -61,400,000 | -18,900,000 | -63,500,000 | -108,200,000 | -91,500,000 | -75,000,000 | -80,200,000 | -121,100,000 | -93,000,000 | -64,700,000 | -60,200,000 | -36,600,000 | -60,800,000 | -13,600,000 | 0 | 15,200,000 | -49,900,000 | -29,200,000 | -17,700,000 | -27,100,000 | -8,300,000 | -11,000,000 | -11,900,000 | -12,700,000 | -17,300,000 | -17,600,000 | -16,100,000 | -10,500,000 | -11,500,000 | -11,600,000 | -7,400,000 | -6,300,000 | -8,000,000 | -3,700,000 | -4,000,000 | -3,900,000 | -2,300,000 | -2,200,000 | -2,000,000 | -1,400,000 | -1,404,000 | -2,894,000 | -2,882,000 | -2,320,000 | -3,549,000 | -1,506,000 | -1,160,000 | -1,791,000 | -2,326,000 | -2,093,000 | -1,483,000 | -958,000 | -463,000 | -825,000 | -754,000 | -950,000 | -431,000 | -609,000 | -392,000 | -1,060,000 | |
free cash flows | 499,400,000 | 192,100,000 | 574,100,000 | 203,000,000 | 154,400,000 | 176,800,000 | 75,200,000 | 263,300,000 | 193,000,000 | 81,100,000 | 212,400,000 | 128,900,000 | 136,500,000 | 69,000,000 | 185,000,000 | 81,300,000 | -4,000,000 | 25,600,000 | 126,200,000 | -31,400,000 | -36,900,000 | 111,800,000 | 111,000,000 | 93,300,000 | -11,700,000 | 143,700,000 | 109,700,000 | 14,600,000 | -17,400,000 | 16,000,000 | 29,700,000 | 33,100,000 | -19,700,000 | 24,300,000 | 1,600,000 | -17,000,000 | -4,300,000 | 6,900,000 | 9,600,000 | -11,700,000 | -300,000 | 10,500,000 | 10,100,000 | -4,600,000 | 7,700,000 | 2,200,000 | -6,300,000 | 2,100,000 | -600,000 | -1,100,000 | -5,900,000 | -11,961,000 | -8,944,000 | -9,211,000 | -12,484,000 | -15,119,000 | -8,247,000 | -3,686,000 | -11,080,000 | -15,790,000 | -11,563,000 | -10,788,000 | -11,395,000 | -9,636,000 | -10,633,000 | -11,790,000 | -10,322,000 | 2,095,000 | -12,226,000 | -12,293,000 | -17,519,000 | |
investing activities | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
purchases of marketable securities | -688,600,000 | 0 | -175,900,000 | -608,200,000 | -462,500,000 | -306,900,000 | -784,200,000 | -992,400,000 | -798,000,000 | -1,340,300,000 | -809,600,000 | -254,000,000 | -597,200,000 | -546,500,000 | -368,300,000 | -369,900,000 | -802,000,000 | -403,100,000 | -1,374,200,000 | -365,800,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from sale and maturity of marketable securities | 468,200,000 | 409,600,000 | 466,200,000 | 638,700,000 | 650,200,000 | 405,200,000 | 630,600,000 | 666,800,000 | 1,121,800,000 | 719,000,000 | 671,400,000 | 859,400,000 | 697,600,000 | 740,000,000 | 602,200,000 | 543,800,000 | 241,800,000 | 501,000,000 | 537,000,000 | 838,300,000 | 790,000,000 | 952,000,000 | 449,000,000 | 319,500,000 | 530,000,000 | 423,400,000 | 259,200,000 | 291,300,000 | 222,500,000 | 161,100,000 | ||||||||||||||||||||||||||||||||||||||||||
purchases of property and equipment | -76,600,000 | -101,900,000 | -80,500,000 | -94,100,000 | -87,000,000 | -124,600,000 | -111,200,000 | -66,100,000 | -56,900,000 | -52,500,000 | -50,400,000 | -59,000,000 | -74,700,000 | -63,500,000 | -108,200,000 | -91,500,000 | -101,600,000 | -80,200,000 | -108,100,000 | -101,200,000 | -99,700,000 | -60,200,000 | -47,400,000 | -58,200,000 | -33,200,000 | |||||||||||||||||||||||||||||||||||||||||||||||
purchases of non-marketable equity securities | -1,500,000 | -1,200,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
other investing activities | 100,000 | 1,000,000 | 0 | -500,000 | -10,200,000 | -2,200,000 | -5,400,000 | 2,300,000 | 900,000 | -2,500,000 | -2,000,000 | -10,000,000 | 0 | -2,300,000 | 14,600,000 | 0 | -4,000,000 | -500,000 | -700,000 | -7,800,000 | -2,400,000 | -400,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||
net cash from investing activities | -298,500,000 | 306,600,000 | 192,800,000 | -63,600,000 | 100,200,000 | -303,700,000 | 210,300,000 | -188,900,000 | 74,800,000 | 414,900,000 | -179,500,000 | -555,900,000 | -186,700,000 | -194,100,000 | 229,300,000 | -144,900,000 | -411,800,000 | -496,100,000 | 29,000,000 | 363,200,000 | -112,200,000 | -24,000,000 | -9,300,000 | -1,115,300,000 | 130,600,000 | -94,300,000 | -412,800,000 | -639,400,000 | 131,300,000 | 30,900,000 | 4,600,000 | -159,900,000 | -15,400,000 | -36,600,000 | -85,300,000 | -21,400,000 | -17,300,000 | -17,800,000 | -9,600,000 | -11,200,000 | -12,700,000 | -5,700,000 | -7,200,000 | -25,900,000 | -3,800,000 | -4,000,000 | -4,300,000 | 500,000 | 1,700,000 | 6,100,000 | 12,600,000 | 6,553,000 | 3,494,000 | 6,722,000 | 11,631,000 | -3,446,000 | -10,602,000 | -39,099,000 | 6,776,000 | -20,429,000 | 7,327,000 | 3,513,000 | -16,021,000 | |||||||||
financing activities | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
net proceeds from issuance of common stock | 12,700,000 | 0 | 13,900,000 | 0 | 14,200,000 | 0 | 14,800,000 | 0 | 13,400,000 | 0 | 14,300,000 | 0 | 12,300,000 | 0 | 12,400,000 | 0 | 10,100,000 | 0 | 11,600,000 | 0 | 8,700,000 | 0 | 8,600,000 | 0 | 6,700,000 | 0 | 6,800,000 | 100,000 | 5,000,000 | 200,000 | 5,400,000 | 1,000,000 | 4,200,000 | 4,300,000 | 400,000 | 5,300,000 | 500,000 | 5,100,000 | 1,000,000 | 3,800,000 | 2,800,000 | 5,900,000 | 4,900,000 | 5,500,000 | 6,600,000 | 2,200,000 | 9,700,000 | 5,100,000 | 1,900,000 | 2,300,000 | 2,700,000 | 694,000 | 1,334,000 | 452,000 | 1,120,000 | 47,000 | 1,033,000 | 71,941,000 | 1,688,000 | 33,485,000 | 1,850,000 | 1,397,000 | 33,814,000 | 79,000 | 343,000 | 78,000 | 45,810,000 | 66,000 | 384,000 | 259,000 | 1,053,000 | 207,000 |
payments for taxes related to net share settlement of equity awards | -35,800,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
other financing activities | -1,900,000 | -1,900,000 | -1,700,000 | -1,700,000 | -1,700,000 | -1,600,000 | -1,300,000 | -1,400,000 | -8,700,000 | 4,900,000 | -1,200,000 | -1,100,000 | -1,100,000 | -1,000,000 | -7,200,000 | -4,300,000 | -4,800,000 | -800,000 | -800,000 | -400,000 | -7,900,000 | -4,900,000 | -4,100,000 | -200,000 | -200,000 | -800,000 | -100,000 | -200,000 | -100,000 | |||||||||||||||||||||||||||||||||||||||||||
net cash from financing activities | -25,000,000 | -1,522,200,000 | -175,000,000 | -1,700,000 | 12,500,000 | -1,600,000 | -736,500,000 | -1,400,000 | 4,700,000 | -631,900,000 | -637,400,000 | 939,500,000 | 11,200,000 | -1,000,000 | -552,500,000 | -4,300,000 | 5,300,000 | -800,000 | 10,800,000 | -400,000 | 800,000 | -4,900,000 | 4,500,000 | 906,000,000 | 6,500,000 | -100,000 | 6,000,000 | -100,000 | 4,900,000 | 701,600,000 | 5,400,000 | -800,000 | 4,200,000 | 4,300,000 | 314,400,000 | 80,300,000 | 500,000 | 5,100,000 | -700,000 | 3,200,000 | 2,200,000 | 5,400,000 | 4,300,000 | 4,900,000 | 6,100,000 | 1,600,000 | 9,200,000 | 4,900,000 | 1,900,000 | 2,300,000 | 2,700,000 | 7,294,000 | 1,334,000 | 452,000 | 1,120,000 | 47,000 | 958,000 | 71,716,000 | 1,463,000 | 33,260,000 | 1,625,000 | 1,172,000 | 33,589,000 | -146,000 | -226,000 | -491,000 | 45,242,000 | -503,000 | -185,000 | -310,000 | 3,710,000 | -204,000 |
effect of exchange rate changes on cash, cash equivalents and restricted cash | -2,800,000 | 3,800,000 | -1,100,000 | 16,500,000 | 2,300,000 | -11,200,000 | 8,600,000 | -1,000,000 | -3,800,000 | 6,100,000 | -3,500,000 | -2,200,000 | 1,100,000 | 6,800,000 | -7,300,000 | -4,300,000 | -1,000,000 | -500,000 | -1,000,000 | 500,000 | -400,000 | 1,300,000 | 1,000,000 | 300,000 | -500,000 | 1,000,000 | -1,400,000 | -900,000 | 600,000 | 3,200,000 | 400,000 | -900,000 | -900,000 | |||||||||||||||||||||||||||||||||||||||
increase in cash, cash equivalents and restricted cash | 199,300,000 | -917,800,000 | 676,600,000 | 254,200,000 | 298,800,000 | -15,100,000 | -318,100,000 | 88,100,000 | 284,900,000 | -77,300,000 | -551,200,000 | -55,800,000 | -37,300,000 | -391,600,000 | 286,100,000 | 424,900,000 | -84,000,000 | 144,400,000 | 143,800,000 | -54,900,000 | 138,500,000 | 148,600,000 | 769,400,000 | 67,200,000 | -120,200,000 | -20,800,000 | ||||||||||||||||||||||||||||||||||||||||||||||
cash, cash equivalents and restricted cash, beginning of period | 919,100,000 | 0 | 0 | 0 | 607,300,000 | 0 | 0 | 0 | 567,500,000 | 0 | 0 | 0 | 643,300,000 | 0 | 0 | 0 | 1,053,600,000 | 0 | 0 | 0 | 818,200,000 | 0 | 0 | 0 | 446,400,000 | 0 | 0 | 0 | 1,137,100,000 | 0 | 0 | 0 | 441,500,000 | |||||||||||||||||||||||||||||||||||||||
cash, cash equivalents and restricted cash, end of period | 1,118,400,000 | -917,800,000 | 676,600,000 | 254,200,000 | 906,100,000 | -15,100,000 | -318,100,000 | 88,100,000 | 852,400,000 | -77,300,000 | -551,200,000 | 571,700,000 | 624,300,000 | -55,800,000 | -37,300,000 | 19,300,000 | 717,100,000 | -391,600,000 | 286,100,000 | 424,900,000 | 734,200,000 | 144,400,000 | 143,800,000 | -54,900,000 | 584,900,000 | 50,300,000 | -313,700,000 | -575,900,000 | 1,285,700,000 | 769,400,000 | 67,200,000 | -120,200,000 | 420,700,000 | |||||||||||||||||||||||||||||||||||||||
reconciliation of cash, cash equivalents and restricted cash, end of period: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cash and cash equivalents | 1,118,200,000 | -918,000,000 | 676,700,000 | 254,100,000 | 904,900,000 | -15,100,000 | -318,000,000 | 88,000,000 | 851,200,000 | -77,400,000 | -551,200,000 | 571,700,000 | 623,200,000 | -55,800,000 | -37,300,000 | 19,400,000 | 716,000,000 | -391,700,000 | 285,500,000 | 425,000,000 | 733,800,000 | 144,100,000 | 143,500,000 | -54,600,000 | 584,600,000 | 50,600,000 | -313,600,000 | -575,900,000 | 1,285,100,000 | 769,600,000 | ||||||||||||||||||||||||||||||||||||||||||
restricted cash | 200,000 | 200,000 | -100,000 | 100,000 | 1,200,000 | 0 | -100,000 | 100,000 | 1,200,000 | 100,000 | 0 | 0 | 1,100,000 | 0 | 0 | -100,000 | 1,100,000 | 100,000 | 600,000 | -100,000 | 400,000 | 300,000 | 300,000 | -300,000 | -100,000 | 0 | 600,000 | -200,000 | 0 | 0 | 300,000 | 0 | 700,000 | 0 | 0 | 0 | -100,000 | 0 | 325,000 | 225,000 | 225,000 | 225,000 | 225,000 | 25,000 | 225,000 | 225,000 | 569,000 | 494,000 | 568,000 | 569,000 | 569,000 | 569,000 | -5,063,000 | |||||||||||||||||||
total cash, cash equivalents and restricted cash | 1,118,400,000 | -917,800,000 | 676,600,000 | 254,200,000 | 906,100,000 | -15,100,000 | -318,100,000 | 88,100,000 | 852,400,000 | -77,300,000 | -551,200,000 | 571,700,000 | 624,300,000 | -55,800,000 | -37,300,000 | 19,300,000 | 717,100,000 | -391,600,000 | 286,100,000 | 424,900,000 | 734,200,000 | 144,400,000 | 143,800,000 | -54,900,000 | 584,900,000 | 50,300,000 | -313,700,000 | -575,900,000 | 1,285,700,000 | 769,400,000 | ||||||||||||||||||||||||||||||||||||||||||
supplemental disclosure of non-cash investing and financing transactions: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
acquisition of property and equipment included in accounts payable and accrued liabilities | 50,400,000 | -5,300,000 | -5,900,000 | 57,600,000 | -13,100,000 | 50,000,000 | 40,700,000 | -6,400,000 | -2,400,000 | 55,800,000 | 26,600,000 | -13,000,000 | 8,200,000 | 35,000,000 | 10,800,000 | -2,600,000 | 19,600,000 | 15,200,000 | -3,000,000 | 10,100,000 | -3,300,000 | 2,000,000 | 4,300,000 | 1,600,000 | -700,000 | 5,600,000 | ||||||||||||||||||||||||||||||||||||||||||||||
right-of-use assets obtained in exchange for operating lease liabilities | 400,000 | 2,200,000 | -500,000 | 7,600,000 | 1,100,000 | 1,900,000 | 2,200,000 | 1,900,000 | -1,300,000 | 1,800,000 | 500,000 | 9,900,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
right-of-use assets obtained in exchange for finance lease liabilities | 2,000,000 | 0 | 300,000 | 1,100,000 | 2,000,000 | 2,400,000 | 7,400,000 | 300,000 | 500,000 | 1,000,000 | 5,200,000 | 1,700,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
purchases of treasury stock | -312,800,000 | 0 | -500,000,000 | 0 | 0 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from issuance of convertible notes, net of issuance costs | 0 | 0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
purchases of capped call transactions | 0 | 0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
payments for conversions of senior convertible notes | -136,800,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
repayments for maturity of senior convertible notes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
purchase of marketable securities | -883,800,000 | -50,700,000 | -112,500,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
acquisitions, net of cash acquired | 0 | -700,000 | 0 | -3,200,000 | 1,400,000 | 0 | -100,000 | 0 | 0 | 0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from issuance of senior convertible notes, net of issuance costs | 0 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
shares issued for conversions of 2023 notes | 35,900,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
shares received under note hedge upon conversion of 2023 notes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
collaborative research and development fee | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss on extinguishment of debt | 700,000 | 0 | 500,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
realized loss on equity investment | -900,000 | -200,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
decrease in cash, cash equivalents and restricted cash | -19,000,000 | -336,500,000 | -313,700,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
realized (gain) loss on equity investment | 0 | 0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
repurchase of convertible notes | 0 | 0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
shares received under note hedge upon conversions of 2023 notes | -33,500,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
* we adjusted our 2021 amounts to reflect the simplified convertible instruments accounting guidance, which we adopted on a full retrospective basis. refer to note 1 “organization and significant accounting policies” for further information. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
shares issued for repurchase and conversions of senior convertible notes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
common stock issued for repurchase and conversions of senior convertible notes | 160,900,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
non-cash collaborative research and development fee through issuance of common stock | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
unrealized gain on equity investment | -7,400,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from sale of warrants | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
purchase of convertible note hedge | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cash flows from investing activities: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cash flows from financing activities: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
right-of-use assets obtained in exchange for lease liabilities | 0 | 5,300,000 | 1,400,000 | 10,600,000 | 45,200,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
purchases of other equity investments | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
deferred revenue, deferred rent and other liabilities | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
purchase of other equity investments | 0 | -1,200,000 | 0 | 0 | 0 | -1,000,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
purchase of property and equipment | -46,900,000 | -39,300,000 | -17,700,000 | -23,800,000 | -10,300,000 | -15,300,000 | -13,500,000 | -12,000,000 | -22,900,000 | -17,600,000 | -16,100,000 | -10,500,000 | -11,500,000 | -11,600,000 | -7,400,000 | -6,300,000 | -8,000,000 | -3,700,000 | -4,000,000 | -3,900,000 | -2,300,000 | -2,200,000 | -2,000,000 | -1,400,000 | -1,404,000 | -2,894,000 | -2,882,000 | -2,320,000 | -3,549,000 | -1,506,000 | -1,160,000 | -1,791,000 | -2,326,000 | -2,093,000 | -1,483,000 | -958,000 | -463,000 | -825,000 | -754,000 | -950,000 | -431,000 | -609,000 | -392,000 | -1,060,000 | ||||||||||||||||||||||||||||
proceeds from issuance of convertible debt, net of issuance costs | 0 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from short-term borrowings | 0 | 0 | 75,000,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
repayment of short-term borrowings | 0 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cash flows from operating activities: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
unrealized loss on equity investment | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
payments on acquisition related contingent consideration liability | 0 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
(income) income from equity investments | 0 | 4,200,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
deferred revenue, deferred rent, and other liabilities | -3,000,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
unrealized income on equity investment | 4,800,000 | 9,300,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
realized income on equity investment | 0 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
deferred tax | -1,100,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
deferred revenue | -3,300,000 | 3,900,000 | -300,000 | 900,000 | 300,000 | 200,000 | 400,000 | -100,000 | 0 | -200,000 | -800,000 | 800,000 | -500,000 | 600,000 | 300,000 | -300,000 | -100,000 | 200,000 | -100,000 | -200,000 | -1,100,000 | 181,000 | -410,000 | -478,000 | 807,000 | 135,000 | -596,000 | -596,000 | -595,000 | -917,000 | 394,000 | -1,721,000 | -1,977,000 | -957,000 | -1,355,000 | -1,564,000 | -399,000 | 11,641,000 | -42,000 | -42,000 | 463,000 | |||||||||||||||||||||||||||||||
deferred rent and other liabilities | -700,000 | 900,000 | 400,000 | 400,000 | 300,000 | 1,200,000 | 2,700,000 | 1,300,000 | 700,000 | 200,000 | -400,000 | 1,900,000 | 400,000 | 500,000 | -100,000 | -100,000 | -100,000 | -200,000 | 0 | 501,000 | -88,000 | -32,000 | 119,000 | -22,000 | -33,000 | -9,000 | -15,000 | 70,000 | 222,000 | -41,000 | -49,000 | 2,000 | -42,000 | -36,000 | 27,000 | 210,000 | 0 | 6,000 | 7,000 | |||||||||||||||||||||||||||||||||
reconciliation of cash, cash equivalents and restricted cash: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
purchase of available-for-sale marketable securities | -192,100,000 | -32,000,000 | -50,500,000 | -84,000,000 | -7,400,000 | -9,100,000 | -9,200,000 | -10,100,000 | -10,800,000 | -9,800,000 | -7,900,000 | -4,900,000 | -22,600,000 | -3,900,000 | -3,400,000 | -3,000,000 | -3,900,000 | -3,500,000 | -4,000,000 | -4,900,000 | -10,118,000 | -13,999,000 | -15,665,000 | -26,618,000 | -24,611,000 | -28,614,000 | -45,439,000 | -3,991,000 | -29,759,000 | -4,033,000 | -7,390,000 | -32,265,000 | -11,673,000 | -5,192,000 | -3,044,000 | -45,361,000 | -4,036,000 | -8,000 | -15,378,000 | -17,564,000 | ||||||||||||||||||||||||||||||||
proceeds from the maturity of available-for-sale marketable securities | 42,500,000 | 32,900,000 | 27,400,000 | 10,700,000 | 8,900,000 | 9,500,000 | 7,500,000 | 10,600,000 | 11,100,000 | 8,700,000 | 9,600,000 | 4,500,000 | 4,700,000 | 3,800,000 | 3,400,000 | 2,600,000 | 6,700,000 | 7,400,000 | 12,100,000 | 18,900,000 | 18,075,000 | 20,387,000 | 25,269,000 | 40,569,000 | 24,710,000 | 19,518,000 | 7,500,000 | 12,558,000 | 11,650,000 | 13,453,000 | 12,386,000 | 17,202,000 | 18,373,000 | 18,200,000 | 10,283,000 | 7,000,000 | 10,501,000 | 12,099,000 | 8,992,000 | 32,210,000 | 31,540,000 | |||||||||||||||||||||||||||||||
reconciliation of cash and restricted cash: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cash | -120,200,000 | 420,400,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
total cash and restricted cash | -120,200,000 | 420,700,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
other non-cash expenses | -2,900,000 | 5,700,000 | 400,000 | 100,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
repayment of long-term debt | 0 | 0 | -1,700,000 | -600,000 | -600,000 | -500,000 | -600,000 | -600,000 | -500,000 | -600,000 | -500,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
effect of exchange rate changes on cash and cash equivalents | 2,300,000 | -1,000,000 | -200,000 | -100,000 | -21,000 | -1,000 | 19,000 | -7,000 | -34,000 | -7,000 | -43,000 | 10,000 | -8,000 | -5,000 | 5,000 | -26,000 | 17,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
increase in cash and cash equivalents | 6,200,000 | 242,400,000 | 59,000,000 | -3,200,000 | 10,200,000 | 800,000 | 17,600,000 | 13,500,000 | -17,600,000 | 13,700,000 | 3,800,000 | 2,500,000 | 9,800,000 | 5,200,000 | 9,300,000 | 10,800,000 | 3,309,000 | -1,241,000 | 866,000 | 2,566,000 | -14,970,000 | -16,366,000 | 30,084,000 | -1,084,000 | -640,000 | -561,000 | -4,610,000 | 7,123,000 | -3,424,000 | 8,058,000 | -321,000 | -18,989,000 | 837,000 | |||||||||||||||||||||||||||||||||||||||
cash and cash equivalents, beginning of period | 0 | 0 | 94,500,000 | 0 | 0 | 0 | 86,100,000 | 0 | 0 | 0 | 71,800,000 | 0 | 0 | 43,200,000 | 0 | 0 | 0 | 8,100,000 | 0 | 0 | 2,553,000 | 0 | 0 | 4,889,000 | 0 | 0 | 3,577,000 | 0 | 0 | 12,700,000 | 0 | 0 | 23,115,000 | |||||||||||||||||||||||||||||||||||||||
cash and cash equivalents, end of period | 6,200,000 | 242,400,000 | 153,500,000 | 10,200,000 | 9,600,000 | 77,900,000 | 17,600,000 | 13,500,000 | 54,200,000 | -16,366,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
issuance of common stock in connection with acquisition | 0 | 0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
acquisition-related holdback liability | 0 | 0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
assets acquired and financing obligation under build-to-suit leasing arrangement | 0 | 0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
non-cash research and development charge through issuance of common stock | 0 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
impairment of intangible assets | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cash and cash equivalents, ending of period | 3,800,000 | 45,700,000 | 9,800,000 | 5,200,000 | 9,300,000 | 18,900,000 | -1,241,000 | 866,000 | 5,119,000 | 3,805,000 | -561,000 | -4,610,000 | 10,700,000 | 2,154,000 | -5,068,000 | 9,276,000 | -321,000 | -18,989,000 | 23,952,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
supplemental disclosure of cash flow information | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cash paid during the year for interest | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cash paid during the year for taxes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
issuance of common stock in connection with contingent consideration settlement | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
accretion and amortization related to marketable securities | 100,000 | 0 | 100,000 | 0 | 100,000 | 100,000 | 100,000 | 0 | 0 | 100,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
amortization of debt issuance costs | 0 | 100,000 | 0 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 100,000 | 0 | 6,000 | 24,000 | 6,000 | 68,000 | -19,000 | 145,000 | 52,000 | 134,000 | 138,000 | 135,000 | 139,000 | 139,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||
loss on disposal of equipment | 100,000 | 0 | 200,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
decrease in cash and cash equivalents | -8,200,000 | 2,154,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
change in fair value of contingent consideration | -900,000 | -1,000,000 | 1,200,000 | 500,000 | 1,000,000 | 700,000 | 300,000 | -240,000 | 278,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
adjustments to reconcile net income to cash from in operating activities: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
release of valuation allowance against deferred tax assets | 16,000 | 0 | 0 | -1,316,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
net proceeds from issuance of long-term debt | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
repayment of equipment loan | 0 | -75,000 | -225,000 | -225,000 | -225,000 | -225,000 | -225,000 | -225,000 | -225,000 | -569,000 | -569,000 | -568,000 | -912,000 | -569,000 | -226,000 | -343,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
supplemental disclosure of non-cash transactions | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
issuance of common stock in connection with acquisition and contingent consideration | 0 | 0 | 6,063,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
accretion and amortization related to investments | 100,000 | 136,000 | 166,000 | 213,000 | 285,000 | 299,000 | 294,000 | 170,000 | 146,000 | 149,000 | 191,000 | 227,000 | 154,000 | 128,000 | 238,000 | 334,000 | 191,000 | 27,000 | 21,000 | -10,000 | -37,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||
accretion of non-cash interest expense related to convertible notes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss on debt extinguishment upon conversion of convertible debt | 3,000 | 312,000 | 245,000 | 7,930,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cash and cash equivalents, beginning of year | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cash and cash equivalents, ending of year | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
supplemental disclosure of cash flow information: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
non-cash investing and financing transactions: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
conversion of convertible notes to common stock | -763,000 | 4,001,000 | 1,549,000 | 41,483,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
other non-cash | -60,000 | 61,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
non-cash restructuring charge | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from the sale of equipment | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
unrealized gain on marketable securities | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
accretion related to convertible debt discount | 51,000 | 89,000 | 919,000 | 1,241,000 | 1,186,000 | 1,135,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
compensation expense associated with stock options issued to consultants | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from equipment loan | 343,000 | 0 | -343,000 | 3,000,000 | 0 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
non-cash restructuring benefit | 0 | 0 | -362,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from issuance of senior convertible notes | 0 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
payment of senior convertible notes issuance costs | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
purchase of senior convertible notes call spread options | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
net cash provided by/(used in) investing activities | 12,183,000 | 6,485,000 | -39,311,000 | 11,482,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
common shares received as settlement for a call spread option | 0 | 0 | 869,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
stock-based compensation | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
net cash provided/(used) in investing activities | 13,586,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
conversion of series a, b, c, and d preferred stock | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
accretion to redemption value of series b, series c, and series d redeemable convertible preferred stock | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
other assets | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
other liabilities | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
non-cash investing and financing activities | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
deferred rent | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
net proceeds from issuance of preferred stock | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
interest on converted notes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
prepaid and other current assets | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
proceeds on sale of equipment | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
proceeds from convertible notes payable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
purchase of technology in exchange for common stock | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
conversion of notes payable into series b preferred stock | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
unrealized loss on marketable securities |
