7Baggers
Quarterly
Annual
    Unit: USD2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-09-30 2018-06-30 2018-03-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-09-30 2014-06-30 2014-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31 2010-12-31 2010-09-30 2010-06-30 2010-03-31 2009-12-31 2009-09-30 2009-06-30 2009-03-31 2008-12-31 2008-09-30 2008-06-30 2008-03-31 2007-12-31 2007-09-30 2006-12-31 2005-12-31 
      
    		                                                                        
      assets
    		                                                                        
      current assets:
    		                                                                        
      cash and cash equivalents
    		1,835,700,000 1,159,000,000 904,900,000 606,100,000 621,200,000 939,200,000 851,200,000 566,300,000 643,700,000 1,194,900,000 623,200,000 642,300,000 698,100,000 735,400,000 716,000,000 1,052,600,000 1,444,300,000 1,158,800,000 733,800,000 817,600,000 673,500,000 530,000,000 584,600,000 446,200,000 395,600,000 709,200,000 1,285,100,000 367,400,000 300,200,000 420,400,000 402,100,000 395,900,000 153,500,000 94,500,000 97,700,000 87,500,000 77,900,000 86,100,000 85,300,000 67,700,000 54,200,000 63,200,000 49,500,000 45,700,000 43,200,000 33,400,000 28,200,000 18,900,000 8,100,000 4,744,000 5,985,000 5,119,000 2,553,000 17,523,000 33,889,000 3,805,000 4,889,000 5,529,000 6,090,000 10,700,000 3,577,000 6,362,000 4,208,000 9,276,000 12,700,000 4,642,000 4,963,000 23,952,000 23,115,000 15,176,000 18,167,066 37,247,064 
      short-term marketable securities
    		1,486,400,000 1,770,300,000 1,796,500,000 1,973,300,000 1,871,100,000 2,181,500,000 2,045,800,000 2,157,800,000 2,596,600,000 2,441,300,000 1,943,800,000 1,813,900,000 1,673,800,000 2,019,400,000 1,972,200,000 1,678,600,000 1,253,600,000 1,426,100,000 1,898,800,000 1,890,100,000 1,930,300,000 1,978,800,000 925,900,000 1,087,100,000 1,034,300,000 668,300,000 72,900,000 301,300,000 305,900,000 113,500,000                                           
      accounts receivable
    		1,109,600,000 1,348,800,000 1,155,200,000 1,005,700,000 1,002,000,000 945,200,000 978,600,000 973,900,000 785,700,000 750,600,000 636,800,000 713,300,000 564,100,000 560,800,000 544,500,000 514,300,000 529,100,000 483,500,000 443,400,000 428,500,000 370,000,000 296,500,000 300,700,000 286,300,000 234,900,000 217,300,000 204,700,000 169,800,000 162,000,000 123,900,000 110,500,000 101,700,000 85,900,000 101,700,000 76,800,000 73,800,000 67,300,000 74,100,000 55,800,000 45,500,000 40,200,000 31,400,000 28,600,000 23,800,000 26,100,000 21,600,000 17,700,000 16,300,000 19,500,000 12,357,000 12,900,000 12,543,000 12,547,000 9,003,000 8,694,000 7,158,000 6,671,000 5,102,000 4,661,000 3,801,000 3,490,000 2,487,000 2,067,000 1,345,000 1,118,000 429,000 568,000 321,000 215,000 171,000 120,477  
      inventory
    		604,100,000 570,700,000 538,200,000 542,600,000 586,300,000 570,300,000 589,100,000 559,600,000 498,600,000 421,100,000 366,000,000 306,700,000 311,000,000 339,500,000 342,200,000 357,300,000 351,300,000 319,300,000 289,700,000 234,700,000 200,700,000 165,300,000 141,900,000 119,800,000 120,400,000 117,900,000 101,100,000 55,200,000 46,200,000 51,600,000 43,300,000 42,800,000 46,500,000 45,400,000 44,700,000 42,900,000 46,100,000 35,200,000 30,600,000 22,400,000 18,400,000 14,300,000 11,600,000 8,900,000 9,000,000 10,000,000 7,300,000 7,500,000 7,400,000 7,141,000 7,378,000 8,044,000 8,171,000 6,455,000 6,258,000 6,425,000 8,112,000 6,353,000 4,087,000 3,851,000 2,641,000 1,932,000 1,363,000 2,365,000 2,446,000 2,590,000 2,771,000 1,824,000 1,139,000 1,035,000 1,413,024  
      prepaid and other current assets
    		183,700,000 181,400,000 159,000,000 173,700,000 182,200,000 212,200,000 156,000,000 168,300,000 173,800,000 195,000,000 197,600,000 192,600,000 151,500,000 153,600,000 171,700,000 81,600,000 77,900,000 86,500,000 79,400,000 53,900,000 62,600,000 62,400,000 42,600,000 30,000,000 30,500,000 31,500,000 27,000,000 20,400,000 21,700,000 19,900,000 13,300,000 15,700,000 17,000,000 9,200,000 9,800,000 8,700,000 7,500,000 6,800,000 4,000,000 5,000,000 3,800,000 2,800,000 4,000,000 3,500,000 3,400,000 2,500,000 2,800,000 2,200,000 2,000,000 2,688,000 2,527,000 2,051,000 1,781,000 2,457,000 3,011,000 2,304,000 2,690,000 1,460,000 1,614,000 1,436,000 2,773,000 1,239,000 1,819,000 1,344,000 1,426,000 1,382,000 1,757,000 1,118,000 1,614,000 1,598,000 1,313,907 488,015 
      total current assets
    		5,219,500,000 5,030,200,000 4,553,800,000 4,301,400,000 4,262,800,000 4,848,400,000 4,620,700,000 4,425,900,000 4,698,400,000 5,002,900,000 3,767,400,000 3,668,800,000 3,398,500,000 3,808,700,000 3,746,600,000 3,684,400,000 3,656,200,000 3,474,200,000 3,445,100,000 3,424,800,000 3,237,100,000 3,033,000,000 1,995,700,000 1,969,400,000 1,815,700,000 1,744,200,000 1,690,800,000 914,100,000 836,000,000 729,300,000 692,900,000 656,800,000 330,500,000 280,000,000 258,600,000 241,000,000 227,400,000 231,300,000 203,700,000 170,400,000 146,200,000 123,400,000 105,500,000 93,600,000 93,100,000 81,700,000 74,200,000 71,300,000 77,600,000 75,571,000 83,993,000 92,822,000 104,410,000 115,232,000 123,980,000 54,432,000 66,025,000 44,488,000 50,443,000 59,009,000 36,920,000 43,376,000 54,123,000 66,506,000 32,058,000 29,784,000 42,955,000 53,847,000 67,291,000 77,083,000 57,355,923 51,012,767 
      property and equipment
    		1,471,300,000 1,457,300,000 1,364,700,000 1,339,900,000 1,318,800,000 1,183,100,000 1,108,600,000 1,113,100,000 1,078,900,000 1,077,600,000 1,075,500,000 1,055,600,000 1,002,500,000 942,900,000 856,500,000 801,800,000 742,200,000 676,000,000 589,900,000 515,300,000 461,800,000 384,300,000 346,100,000 321,300,000 301,000,000 253,200,000 221,400,000 169,600,000 156,800,000 152,400,000 136,100,000 125,000,000 123,400,000 109,400,000 88,400,000 77,000,000 65,900,000 54,700,000 46,600,000 40,600,000 35,700,000 28,000,000 26,000,000 22,900,000 20,700,000 19,700,000 19,100,000 18,300,000 18,900,000 18,613,000 17,768,000 16,206,000 15,019,000 12,524,000 12,016,000 11,748,000 10,763,000 9,240,000 7,775,000 6,880,000 6,422,000 6,731,000 6,495,000 6,403,000 6,105,000 6,442,000 6,543,000 6,854,000 6,649,000 5,058,000 6,117,685 5,463,491 
      operating lease right-of-use assets
    		54,000,000 56,400,000 59,100,000 62,800,000 67,500,000 71,200,000 68,000,000 71,400,000 73,400,000 76,300,000 78,000,000 80,000,000 73,100,000 77,900,000 82,300,000 88,100,000 91,300,000 94,800,000 98,800,000 93,300,000 94,300,000 71,600,000 73,800,000 71,500,000 34,600,000 35,800,000 27,700,000                                              
      goodwill
    		24,100,000 24,100,000 23,100,000 22,800,000 23,800,000 23,300,000 23,200,000 25,200,000 25,300,000 25,800,000 25,700,000 25,700,000 24,700,000 25,600,000 26,600,000 26,500,000 23,900,000 19,100,000 18,900,000 19,300,000 19,000,000 18,700,000 18,600,000 18,600,000 18,400,000 18,700,000 18,600,000 18,400,000 11,900,000 12,300,000 12,000,000 11,900,000 11,400,000 11,300,000 11,800,000 11,800,000 3,700,000 3,700,000 3,700,000 3,700,000 3,200,000 3,200,000 3,200,000 3,200,000 3,200,000 3,200,000 3,200,000 3,200,000 3,200,000 3,162,000 3,162,000 3,162,000                     
      intangibles
    		79,000,000 87,200,000 95,200,000 103,400,000 106,200,000 114,500,000 123,300,000 134,500,000 144,500,000 154,200,000 163,600,000 173,300,000 24,400,000 28,000,000 31,400,000                                                          
      deferred tax assets
    		375,600,000 496,300,000 487,300,000 481,200,000 486,500,000 475,800,000 460,700,000 419,400,000 501,300,000 417,000,000 349,100,000 341,200,000 342,300,000 309,500,000 290,800,000 220,800,000 216,300,000 216,400,000 216,700,000 216,400,000                                                     
      other assets
    		276,500,000 175,500,000 168,500,000 173,000,000 88,200,000 82,900,000 77,700,000 75,000,000 74,400,000 66,900,000 56,600,000 47,100,000 33,700,000 24,800,000 22,800,000   23,300,000 20,400,000 21,400,000 21,000,000 14,200,000 13,700,000 14,200,000 16,000,000 14,000,000 15,500,000 12,200,000 2,800,000 2,800,000 1,900,000 1,900,000 1,900,000 1,900,000 1,500,000 1,200,000 400,000 100,000 300,000 500,000 600,000 700,000 700,000 800,000 900,000 800,000 900,000 1,000,000 1,100,000 98,000 98,000 123,000 107,000 98,000 98,000 100,000 101,000 102,000 183,000 236,000 1,192,000 1,210,000 1,275,000 1,335,000 1,933,000 2,010,000 2,147,000 2,284,000 2,405,000 3,348,000   
      total assets
    		7,500,000,000 7,327,000,000 6,751,700,000 6,484,500,000 6,353,800,000 6,799,200,000 6,482,200,000 6,264,500,000 6,596,200,000 6,820,700,000 5,515,900,000 5,391,700,000 4,899,200,000 5,217,400,000 5,057,000,000 4,863,600,000 4,775,900,000 4,503,800,000 4,389,800,000 4,290,500,000 3,833,200,000 3,521,800,000 2,447,900,000 2,395,000,000 2,185,700,000 2,065,900,000 1,974,000,000 1,114,300,000 1,007,500,000 896,800,000 842,900,000 795,600,000 467,200,000 402,800,000 361,900,000 332,800,000 299,400,000 292,000,000 256,700,000 218,400,000 189,300,000 159,400,000 139,700,000 124,900,000 122,500,000 110,100,000 102,300,000 98,800,000 106,000,000 102,796,000 110,522,000 117,962,000 120,475,000 128,793,000 136,369,000 66,555,000 77,164,000 54,105,000 60,565,000 68,314,000 46,948,000 53,956,000 65,101,000 77,946,000 44,366,000 43,075,000 57,053,000 68,962,000 77,259,000 85,489,000 64,552,608 56,726,258 
      liabilities and stockholders’ equity
    		                                                                        
      current liabilities:
    		                                                                        
      accounts payable and accrued liabilities
    		1,932,400,000 1,943,800,000 1,690,600,000 1,585,100,000 1,592,500,000 1,569,800,000 1,446,600,000 1,345,500,000 1,373,100,000 1,156,500,000 965,200,000 901,800,000 764,200,000 688,300,000 603,100,000 573,000,000 598,000,000 482,000,000 502,600,000 481,100,000 397,000,000 315,900,000 267,500,000 256,400,000 232,400,000 196,700,000 169,100,000 135,400,000 117,900,000 88,000,000 80,600,000 72,200,000 65,400,000 68,100,000 58,600,000 49,900,000 45,100,000 38,900,000 34,300,000 24,000,000 21,200,000 20,900,000 20,000,000 15,900,000 14,100,000 12,600,000 9,100,000 7,500,000 8,700,000 10,520,000 7,532,000 7,980,000 6,346,000 6,045,000 4,965,000 4,234,000 5,350,000 7,075,000 5,684,000 5,112,000 5,745,000 4,373,000 4,118,000 3,774,000 4,599,000 2,663,000 3,736,000 3,245,000 4,535,000 2,088,000 2,763,300 6,008,194 
      accrued payroll and related expenses
    		170,200,000 129,300,000 110,800,000 112,000,000 105,800,000 116,100,000 110,500,000 171,000,000 151,300,000 108,600,000 94,800,000 134,300,000 112,700,000 94,800,000 84,700,000 125,200,000 115,300,000 98,100,000 81,400,000 114,300,000 92,100,000 67,400,000 59,000,000 88,500,000 70,900,000 73,900,000 51,300,000 55,000,000 46,100,000 34,200,000 35,300,000 31,400,000 30,100,000 33,400,000 27,000,000 23,300,000 16,700,000 24,900,000 20,400,000 17,000,000 12,100,000 16,800,000 13,000,000 11,000,000 15,100,000 12,400,000 10,100,000 7,200,000 9,200,000 8,662,000 7,930,000 6,251,000 6,804,000 6,961,000 6,403,000 4,703,000 5,730,000 5,623,000 4,883,000 4,048,000 4,406,000 3,560,000 3,158,000 2,187,000 2,115,000 2,722,000 2,431,000 2,410,000 2,537,000 2,644,000 1,557,578 889,362 
      current portion of long-term senior convertible notes
    		1,206,900,000 1,206,100,000 1,205,300,000 1,204,400,000     124,200,000 773,800,000 773,200,000 772,600,000                                                             
      short-term operating lease liabilities
    		23,600,000 23,400,000 22,600,000 22,500,000 22,300,000 21,600,000 20,700,000 21,100,000 21,000,000 21,800,000 22,200,000 20,500,000 20,900,000 21,200,000 20,900,000 20,500,000 19,300,000 18,800,000 18,200,000 16,500,000 15,800,000                                                    
      deferred revenue
    		2,900,000 6,100,000 7,800,000 8,000,000 13,900,000 14,700,000 16,400,000 18,400,000 9,000,000 9,000,000 9,600,000 10,100,000 2,700,000 2,700,000 2,700,000 2,100,000 2,300,000 1,800,000 1,900,000 2,200,000 1,500,000 1,700,000 1,800,000 1,700,000 4,300,000 3,500,000 2,700,000 3,500,000 6,800,000 2,900,000                                           
      total current liabilities
    		3,336,000,000 3,308,700,000 3,037,100,000 2,932,000,000 1,734,500,000 1,722,200,000 1,594,200,000 1,556,000,000 1,678,600,000 2,069,700,000 1,865,000,000 1,839,300,000 900,500,000 807,000,000 711,400,000 720,800,000 734,900,000 600,700,000 604,100,000 614,100,000 506,400,000 400,100,000 342,800,000 360,200,000 322,400,000 288,200,000 235,400,000 193,900,000 170,800,000 125,100,000 118,200,000 105,100,000 171,700,000 102,400,000 86,100,000 73,900,000 64,100,000 66,900,000 58,800,000 44,200,000 37,000,000 40,600,000 35,600,000 29,700,000 32,100,000 27,400,000 21,100,000 16,200,000 19,500,000 20,404,000 16,961,000 16,076,000 14,741,000 14,743,000 13,776,000 11,595,000 15,129,000 17,008,000 15,514,000 15,828,000 18,796,000 17,535,000 16,624,000 14,997,000 14,996,000 7,827,000 8,609,000 8,097,000 8,447,000 6,107,000 5,228,678 7,074,096 
      long-term senior convertible notes
    		1,239,900,000 1,238,900,000 1,238,000,000 1,237,000,000 2,439,600,000 2,437,800,000 2,436,000,000 2,434,200,000 2,432,400,000 2,430,600,000 1,198,500,000 1,197,700,000 1,968,800,000 1,967,300,000 1,965,900,000 1,702,700,000 1,703,500,000 1,710,700,000 1,688,800,000 1,667,200,000 1,645,800,000 1,658,800,000 1,072,400,000 1,059,700,000 1,047,100,000 1,034,700,000 1,022,400,000                                              
      long-term operating lease liabilities
    		50,600,000 54,700,000 59,700,000 65,000,000 71,100,000 76,800,000 75,800,000 80,100,000 83,400,000 86,900,000 89,700,000 94,600,000 82,100,000 87,700,000 93,300,000 98,600,000 102,900,000 107,100,000 111,300,000 101,800,000 103,200,000                                                    
      other long-term liabilities
    		147,400,000 151,600,000 150,300,000 147,900,000 129,600,000 128,100,000 129,400,000 125,600,000 133,900,000 133,100,000 129,700,000 128,300,000 123,300,000 99,500,000 97,100,000 90,000,000 98,500,000 87,700,000 82,400,000 80,900,000 78,500,000 35,300,000 20,900,000 20,100,000 17,600,000 17,500,000 18,100,000                                           683,000   
      total liabilities
    		4,773,900,000 4,753,900,000 4,485,100,000 4,381,900,000 4,374,800,000 4,364,900,000 4,235,400,000 4,195,900,000 4,328,300,000 4,720,300,000 3,282,900,000 3,259,900,000 3,074,700,000 2,961,500,000 2,867,700,000 2,612,100,000 2,639,800,000 2,506,200,000 2,486,600,000 2,464,000,000 2,333,900,000 2,167,900,000 1,513,400,000 1,512,400,000 1,421,400,000 1,377,600,000 1,305,400,000 552,100,000 525,400,000 475,100,000 458,900,000 441,900,000 189,400,000 119,000,000 100,100,000 86,400,000 68,200,000 70,800,000 63,400,000 47,700,000 40,700,000 44,400,000 40,100,000 34,900,000 38,400,000 35,400,000 30,000,000 25,200,000 29,000,000 22,543,000 19,214,000 18,411,000 15,985,000 15,728,000 14,794,000 13,193,000 16,171,000 18,861,000 19,547,000 21,587,000 65,393,000 63,057,000 63,124,000 62,792,000 82,979,000 70,368,000 71,761,000 71,854,000     
      commitments and contingencies
    		                                                                        
      stockholders’ equity:
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at september 30, 2025 and december 31, 2024
    		                                                                        
      common stock
    		400,000 400,000 400,000 400,000 400,000 400,000 400,000 400,000 400,000 400,000 400,000 400,000 400,000 400,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 100,000 70,000 69,000 69,000 68,000 68,000 68,000 63,000 62,000 60,000 58,000 58,000 46,000 46,000 46,000 46,000 30,000 30,000 30,000 30,000 29,000 28,000 28,164 25,417 
      additional paid-in capital
    		2,246,500,000 2,187,500,000 2,142,200,000 2,093,800,000 2,050,500,000 1,992,300,000 2,510,600,000 3,514,600,000 3,618,000,000 2,269,000,000 2,305,600,000 2,258,100,000 2,072,100,000 2,028,900,000 1,996,600,000 2,504,500,000 2,322,100,000 2,193,600,000 2,162,000,000 2,125,300,000 2,153,700,000 2,079,800,000 1,706,500,000 1,675,900,000 1,651,600,000 1,620,400,000 1,590,600,000 1,181,600,000 1,149,100,000 1,122,500,000 1,048,500,000 1,015,600,000 942,300,000 905,700,000 876,000,000 841,800,000 806,000,000 776,800,000 750,400,000 685,300,000 659,500,000 614,100,000 593,600,000 577,900,000 559,500,000 547,500,000 539,100,000 530,300,000 522,600,000 517,418,000 511,206,000 504,773,000 495,626,000 491,964,000 487,203,000 411,610,000 407,375,000 371,789,000 364,133,000 358,190,000 272,730,000 270,496,000 268,024,000 265,921,000 192,743,000 190,744,000 188,605,000 186,249,000 183,325,000 181,285,000 187,162,062 134,257,379 
      accumulated other comprehensive income
    		81,500,000 83,600,000 2,200,000  63,400,000       -11,600,000 -41,100,000 -23,000,000 -6,100,000 500,000 1,400,000 2,800,000 2,900,000 3,200,000 2,800,000 3,500,000 3,700,000 2,300,000 1,000,000 2,000,000 1,600,000                                  -13,000 36,000 63,000 13,000 50,000 -81,000 -45,000 53,000 13,000 34,000 11,923  
      retained earnings
    		2,166,600,000 1,882,800,000 1,703,000,000 1,597,600,000 1,445,900,000 1,311,300,000 1,167,800,000 1,021,400,000 765,100,000 644,400,000 528,500,000 479,900,000 388,100,000 286,900,000 236,000,000                                                          
      treasury stock
    		-1,768,900,000 -1,581,200,000 -1,581,200,000 -1,581,200,000 -1,581,200,000 -831,700,000 -1,394,700,000 -2,451,100,000 -2,080,000,000 -784,100,000 -595,000,000 -595,000,000 -595,000,000 -37,300,000 -37,300,000 -206,200,000 -159,500,000 -100,000,000 -100,000,000 -100,000,000 -100,000,000 -100,000,000 -100,000,000 -100,000,000 -100,000,000 -100,000,000 -100,000,000                                              
      total stockholders’ equity
    		2,726,100,000 2,573,100,000 2,266,600,000 2,102,600,000 1,979,000,000 2,434,300,000 2,246,800,000 2,068,600,000 2,267,900,000 2,100,400,000 2,233,000,000 2,131,800,000 1,824,500,000 2,255,900,000 2,189,300,000 2,251,500,000 2,136,100,000 1,997,600,000 1,903,200,000 1,826,500,000 1,499,300,000 1,353,900,000 934,500,000 882,600,000 764,300,000 688,300,000 668,600,000 562,200,000 482,100,000 421,700,000 384,000,000 353,700,000 277,800,000 283,800,000 261,800,000 246,400,000 231,200,000 221,200,000 193,300,000 170,700,000 148,600,000 115,000,000 99,600,000 90,000,000 84,100,000 74,700,000 72,300,000 73,600,000 77,000,000 80,253,000 91,308,000 99,551,000 104,490,000 113,065,000 121,575,000 53,362,000 60,993,000 35,244,000 41,018,000 46,727,000   1,977,000 15,154,000     7,115,000 17,324,000 56,828,267 49,412,063 
      total liabilities and stockholders’ equity
    		7,500,000,000 7,327,000,000 6,751,700,000 6,484,500,000 6,353,800,000 6,799,200,000 6,482,200,000 6,264,500,000 6,596,200,000 6,820,700,000 5,515,900,000 5,391,700,000 4,899,200,000 5,217,400,000 5,057,000,000 4,863,600,000 4,775,900,000 4,503,800,000 4,389,800,000 4,290,500,000 3,833,200,000 3,521,800,000 2,447,900,000 2,395,000,000 2,185,700,000 2,065,900,000 1,974,000,000 1,114,300,000 1,007,500,000 896,800,000 842,900,000 795,600,000 467,200,000 402,800,000 361,900,000 332,800,000 299,400,000 292,000,000 256,700,000 218,400,000 189,300,000 159,400,000 139,700,000 124,900,000 122,500,000 110,100,000 102,300,000 98,800,000 106,000,000 102,796,000 110,522,000 117,962,000 120,475,000 128,793,000 136,369,000 66,555,000 77,164,000 54,105,000 60,565,000 68,314,000   65,101,000 77,946,000   57,053,000 68,962,000 77,259,000 85,489,000 64,552,608  
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at june 30, 2025 and december 31, 2024
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at march 31, 2025 and december 31, 2024
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at december 31, 2024 and december 31, 2023
    		                                                                        
      accumulated other comprehensive loss
    		   -8,000,000  -38,000,000 -37,300,000 -16,700,000 -35,600,000 -29,300,000 -6,500,000                 -300,000 -1,300,000 -4,900,000 -2,200,000 -1,600,000 -1,300,000 -1,000,000 -700,000 -700,000 -300,000 -300,000 -300,000 -300,000 -300,000 -100,000 -200,000 -100,000 -100,000 -100,000 -100,000 -100,000 -100,000 -93,000 -88,000 -103,000 -80,000 -94,000 -101,000 -83,000 -66,000 -39,000 -5,000 -40,000             
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at september 30, 2024 and december 31, 2023
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at june 30, 2024 and december 31, 2023
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at march 31, 2024 and december 31, 2023
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at december 31, 2023 and december 31, 2022
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at september 30, 2023 and december 31, 2022
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at june 30, 2023 and december 31, 2022
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at march 31, 2023 and december 31, 2022
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at december 31, 2022 and december 31, 2021
    		                                                                        
      * we adjusted our 2021 amounts to reflect the simplified convertible instruments accounting guidance, which we adopted on a full retrospective basis. all periods presented have also been adjusted to reflect the four-for-one stock split. refer to note 1, “organization and significant accounting policies,” to the consolidated financial statements for further information.
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at september 30, 2022 and december 31, 2021
    		                                                                        
      * we adjusted our 2021 amounts to reflect the simplified convertible instruments accounting guidance, which we adopted on a full retrospective basis. all periods presented have also been adjusted to reflect the four-for-one stock split. refer to note 1, “organization and significant accounting policies,” for further information.
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at june 30, 2022 and december 31, 2021
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at march 31, 2022 and december 31, 2021
    		                                                                        
      * we adjusted our 2021 amounts to reflect the simplified convertible instruments accounting guidance, which we adopted on a full retrospective basis. refer to note 1 “organization and significant accounting policies” for further information.
    		                                                                        
      intangibles and other assets
    		               42,000,000 46,000,000                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at december 31, 2021 and december 31, 2020
    		                                                                        
      accumulated deficit
    		               -47,400,000 -28,000,000 -98,900,000 -161,800,000 -202,100,000 -557,300,000 -629,500,000 -675,800,000 -695,700,000 -788,400,000 -834,200,000 -823,700,000 -619,200,000 -665,800,000 -696,000,000 -662,400,000 -660,400,000 -663,300,000 -621,000,000 -613,600,000 -594,800,000 -574,600,000 -555,400,000 -556,900,000 -514,400,000 -510,700,000 -499,100,000 -493,900,000 -487,900,000 -475,400,000 -472,800,000 -466,800,000 -456,700,000 -445,600,000 -437,142,000 -419,879,000 -405,188,000 -391,124,000 -378,873,000 -365,595,000 -358,228,000 -346,378,000 -336,566,000 -323,168,000 -311,481,000 -291,208,000 -279,679,000 -266,156,000 -250,826,000 -231,436,000 -217,986,000 -203,298,000 -189,224,000 -176,252,000    
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at september 30, 2021 and december 31, 2020
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at june 30, 2021 and december 31, 2020
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at march 31, 2021 and december 31, 2020
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at december 31, 2020 and december 31, 2019
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at september 30, 2020 and december 31, 2019
    		                                                                        
      operating lease liabilities, current portion
    		                     15,100,000 14,500,000 13,600,000 14,800,000 14,100,000 12,300,000                                              
      operating lease liabilities, net of current portion
    		                     73,700,000 77,300,000 72,400,000 34,300,000 37,200,000 29,500,000                                              
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at june 30, 2020 and december 31, 2019
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at march 31, 2020 and december 31, 2019
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at december 31, 2019 and december 31, 2018, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at september 30, 2019 and december 31, 2018
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at june 30, 2019 and december 31, 2018
    		                                                                        
      preferred stock, 0.001 par value, 5.0 million shares authorized; no shares issued and outstanding at march 31, 2019 and december 31, 2018
    		                                                                        
      other liabilities
    		                           19,400,000 19,600,000 18,700,000 16,700,000 16,300,000 17,700,000 16,600,000 14,000,000 12,500,000 4,100,000 3,900,000 4,200,000 2,400,000 2,000,000 900,000 1,000,000 1,100,000 1,700,000 2,800,000 3,100,000 2,700,000 2,100,000 1,570,000 1,551,000 1,501,000 963,000 985,000 1,018,000 1,027,000 1,042,000 972,000 750,000 791,000 840,000 839,000 880,000 916,000 889,000 679,000 679,000 673,000 666,000    
      long term senior convertible notes
    		                           338,800,000 335,000,000 331,300,000 324,000,000 320,500,000                                         
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at september 30, 2018 and december 31, 2017, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at june 30, 2018 and december 31, 2017, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at march 31, 2018 and december 31, 2017, respectively
    		                                                                        
      short-term marketable securities, available-for-sale
    		                              123,700,000 100,700,000 27,600,000 29,200,000 29,600,000 28,100,000 28,600,000 29,100,000 28,000,000 29,800,000 29,600,000 11,700,000 11,800,000 11,700,000 11,400,000 14,200,000 18,200,000 26,400,000 40,600,000 48,641,000 55,203,000 65,065,000 79,358,000 79,794,000 71,139,000 33,526,000 42,224,000 24,380,000 33,991,000 39,221,000 24,439,000 31,356,000 44,666,000 52,176,000 14,368,000 20,741,000 32,896,000 26,632,000 41,208,000 59,103,000 36,341,449 13,277,688 
      current portion of deferred revenue
    		                              2,300,000 1,500,000 1,200,000 900,000 500,000 700,000 600,000 800,000 1,600,000 800,000 1,300,000 600,000 300,000 600,000 700,000 600,000 700,000 800,000 1,400,000 1,222,000 1,499,000 1,845,000 1,591,000 1,737,000 2,333,000 2,358,000 3,524,000 3,560,000 4,047,000 5,768,000 7,745,000 8,702,000 8,104,000 7,448,000 6,351,000 167,000 167,000 167,000     
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at september 30, 2017 and december 31, 2016, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at june 30, 2017 and december 31, 2016, respectively
    		                                                                        
      short-term borrowings
    		                                75,000,000                                        
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at march 31, 2017 and december 31, 2016, respectively
    		                                                                        
      intangible assets
    		                                 200,000 1,600,000 1,800,000 2,000,000 2,200,000 2,400,000 2,500,000 2,600,000 3,100,000 3,300,000 3,400,000 3,600,000 3,700,000 3,900,000 4,000,000 4,200,000 4,313,000 4,462,000 4,610,000                     
      current portion of long-term debt
    		                                    1,700,000 2,300,000 2,500,000 2,400,000 2,400,000 2,300,000 2,300,000 2,200,000 2,200,000 1,800,000 1,200,000 700,000 200,000    0 0 75,000 300,000 525,000 750,000 900,000 900,000 900,000 900,000 1,244,000 1,588,000 1,931,000 2,275,000 2,275,000 2,275,000 1,375,000 1,375,000 907,800  
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at december 31, 2016 and december 31, 2015, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at september 30, 2016 and december 31, 2015, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at june 30, 2016 and december 31, 2015, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at march 31, 2016 and december 31, 2015, respectively
    		                                                                        
      restricted cash
    		                                       700,000 1,000,000 1,000,000 1,000,000 1,000,000 1,000,000 1,000,000 1,000,000 1,000,000 1,000,000 1,039,000 1,039,000 1,039,000 939,000 939,000 989,000 1,214,000 1,439,000 1,664,000 2,164,000 2,189,000 2,414,000 2,639,000 3,208,000 3,702,000 4,270,000 4,839,000 5,408,000 5,977,000 914,000  1,079,000 250,000 
      long-term debt, net of current portion
    		                                      400,000 1,100,000 1,700,000 2,900,000 3,500,000 4,100,000 4,600,000 5,200,000 5,800,000 6,300,000 6,800,000          3,283,000 4,968,000 45,757,000 44,683,000 43,667,000 42,706,000 61,425,000 61,650,000 62,219,000 62,788,000 61,031,000 61,375,000 2,118,200  
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at december 31, 2015 and december 31, 2014, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at september 30, 2015 and december 31, 2014, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at june 30, 2015 and december 31, 2014, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at march 31, 2015 and december 31, 2014, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at september 30, 2014 and december 31, 2013, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at june 30, 2014 and december 31, 2013, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at march 31, 2014 and december 31, 2013, respectively
    		                                                                        
      long-term portion of deferred revenue
    		                                                600,000 569,000 702,000 834,000 281,000   571,000  881,000     1,953,000 4,173,000 5,669,000 212,000 254,000 296,000     
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at december 31, 2013 and december 31, 2012, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at september 30, 2013 and december 31, 2012, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at june 30, 2013 and december 31, 2012, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5.0 shares authorized; no shares issued and outstanding at march 31, 2013 and december 31, 2012, respectively
    		                                                                        
      preferred stock, 0.001 par value per share, 5.0 shares authorized; no shares issued and outstanding at december 31, 2012 and december 31, 2011, respectively.
    		                                                0                        
      preferred stock, 0.001 par value, 5,000 shares authorized; no shares issued and outstanding at september 30, 2012 and december 31, 2011, respectively
    		                                                 0                       
      preferred stock, 0.001 par value, 5,000 shares authorized; no shares issued and outstanding at june 30, 2012 and december 31, 2011, respectively
    		                                                  0                      
      preferred stock, 0.001 par value, 5,000 shares authorized; no shares issued and outstanding at march 31, 2012 and december 31, 2011, respectively
    		                                                   0                     
      preferred stock, 0.001 par value per share, 5,000 shares authorized; no shares issued and outstanding at december 31, 2011 and december 31, 2010, respectively.
    		                                                    0                    
      preferred stock, 0.001 par value, 5,000 shares authorized; no shares issued and outstanding at september 30, 2011 and december 31, 2010, respectively
    		                                                     0                   
      preferred stock, 0.001 par value, 5,000 shares authorized; no shares issued and outstanding at june 30, 2011 and december 31, 2010, respectively
    		                                                      0                  
      preferred stock, 0.001 par value, 5,000 shares authorized; no shares issued and outstanding at march 31, 2011 and december 31, 2010, respectively
    		                                                                        
      stockholders’ equity
    		                                                                        
      preferred stock, 0.001 par value per share, 5,000 shares authorized; no shares issued and outstanding at december 31, 2010 and december 31, 2009, respectively.
    		                                                                        
      preferred stock, 0.001 par value, 5,000 shares authorized; no shares issued and outstanding at september 30, 2010 and december 31, 2009, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5,000 shares authorized; no shares issued and outstanding at june 30, 2010 and december 31, 2009, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5,000 shares authorized; no shares issued and outstanding at march 31, 2010 and december 31, 2009, respectively
    		                                                                        
      stockholders’ deficit:
    		                                                                        
      preferred stock, 0.001 par value per share, 5,000 shares authorized; no shares issued and outstanding at december 31, 2009 and december 31, 2008, respectively.
    		                                                                        
      total stockholders’ deficit
    		                                                            -18,445,000 -9,101,000           
      total liabilities and stockholders’ deficit
    		                                                            46,948,000 53,956,000           
      preferred stock, 0.001 par value, 5,000 shares authorized; no shares issued and outstanding at september 30, 2009 and december 31, 2008, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5,000 shares authorized; no shares issued and outstanding at june 30, 2009 and december 31, 2008, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5,000 shares authorized; no shares issued and outstanding at march 31, 2009 and december 31, 2008, respectively
    		                                                                        
      stockholders’ (deficit) equity:
    		                                                                        
      preferred stock, 0.001 par value per share, 5,000 shares authorized; no shares issued and outstanding at december 31, 2008 and december 31, 2007, respectively.
    		                                                                        
      total stockholders’ (deficit) equity
    		                                                                -38,613,000 -27,293,000 -14,708,000 -2,892,000     
      total liabilities and stockholders’ (deficit) equity
    		                                                                44,366,000 43,075,000       
      preferred stock, 0.001 par value, 5,000 shares authorized; no shares issued and outstanding at september 30, 2008 and december 31, 2007, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5,000 shares authorized; no shares issued and outstanding at june 30, 2008 and december 31, 2007, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5,000 shares authorized; no shares issued and outstanding at march 31, 2008 and december 31, 2007, respectively
    		                                                                        
      preferred stock, 0.001 par value, 5,000 shares authorized; no shares issued and outstanding at december 31, 2007 and december 31, 2006, respectively.
    		                                                                        
      preferred stock, 0.001 par value, 5,000,000 shares authorized; no shares issued and outstanding at september 30, 2007 and december 31, 2006, respectively
    		                                                                        
      deferred rent
    		                                                                      377,463 240,099 
      preferred stock, 0.001 par value, 5,000,000 shares authorized; no shares issued and outstanding at december 31, 2006 and december 31, 2005, respectively.
    		                                                                        
      deferred stock-based compensation
    		                                                                        
      deferred offering costs and other assets
    		                                                                        
      liabilities, redeemable convertible preferred stock and stockholders’ equity
    		                                                                        
      accrued clinical trials
    		                                                                       176,540 
      redeemable convertible series b preferred stock, 0.001 par value, no shares and 11,304,114 shares authorized, issued and outstanding at december 31, 2005 and 2004, respectively.
    		                                                                        
      redeemable convertible series c preferred stock, 0.001 par value, no shares and 13,043,478 shares authorized; no shares and 12,790,870 shares issued and outstanding at december 31, 2005 and 2004, respectively.
    		                                                                        
      redeemable convertible series d preferred stock, 0.001 par value, no shares and 8,700,000 shares authorized; no shares and 8,355,886 shares issued and outstanding at december 31, 2005 and 2004, respectively.
    		                                                                        
      preferred stock, 0.001 par value, 5,000,000 shares authorized; no shares issued and outstanding at december 31, 2005 and 2004.
    		                                                                        
      convertible series a preferred stock, 0.001 par value, no shares and 3,000,000 shares authorized; no shares and 3,000,000 issued and outstanding at december 31, 2005 and 2004, respectively.
    		                                                                        
      deficit accumulated during the development stage
    		                                                                        
      total liabilities, redeemable convertible preferred stock and stockholders’ equity
    		                                                                       56,726,258 
    The information provided in this report is taken from www.sec.gov and many other data providers. While we have conducted our best efforts to ensure that the parsed data is accurate, we cannot guarantee its accuracy. Please use caution and understand that any consequences of its use are your own responsibility.