Corcept Therapeutics Incorporated
(NASDAQ:CORT)

Corcept Therapeutics Incorporated discovers, develops, and commercializes drugs for the treatment of severe metabolic, oncologic, and psychiatric disorders in the United States. The company offers Korlym (mifepristone) tablets as a once-daily oral medication for the treatment of hyperglycemia second...

Website: http://www.corcept.com

Founded: 1998

Full Time Employees: 206

Sector: Healthcare

Industry: Biotechnology

Pharmaceuticals

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Unit: USD	2026-03-31	2025-12-31	2025-09-30	2025-06-30	2025-03-31	2024-12-31	2024-09-30	2024-06-30	2024-03-31	2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2017-06-30	2017-03-31	2016-12-31	2016-09-30	2016-06-30	2016-03-31	2015-12-31	2015-09-30	2015-06-30	2015-03-31	2014-12-31	2014-09-30	2014-06-30	2014-03-31	2013-12-31	2013-09-30	2013-06-30	2013-03-31	2012-12-31	2012-09-30	2012-06-30	2012-05-13	2012-03-31	2011-12-31	2011-09-30	2011-06-30	2011-05-13	2011-03-31	2010-12-31	2010-09-30	2010-06-30	2010-05-13	2010-03-31	2009-12-31	2009-09-30	2009-06-30	2009-05-13	2009-03-31	2008-12-31	2008-09-30	2008-06-30	2008-05-13	2008-03-31	2007-12-31	2007-09-30	2007-06-30	2007-05-13	2007-03-31	2006-12-31	2006-09-30	2006-06-30	2006-05-13	2006-03-31	2005-12-31	2005-09-30	2005-06-30	2005-05-13	2005-03-31	2004-12-31	2004-09-30	2004-06-30	2004-03-31

product revenue	164,903,000	202,125,000	207,638,000	194,430,000	157,214,000	181,890,000	182,546,000	163,796,000	146,808,000	135,405,000	123,601,000	117,715,000	105,654,000	103,056,000	101,728,000	103,386,000	93,688,000	98,822,000	96,131,000	91,588,000	79,437,000	85,735,000	86,327,000	88,565,000	93,247,000	87,895,000	81,505,000	72,257,000	64,829,000	66,831,000	64,445,000	62,312,000	57,659,000	53,280,000	42,763,000	35,559,000	27,599,000	23,812,000	21,725,000	19,724,000	16,061,000	8,829,750	13,261,000	11,956,000	10,102,000
operating expenses:
cost of sales	2,883,000	2,545,000	4,596,000	3,433,000	2,403,000	2,956,000	2,867,000	2,524,000	2,535,000	1,877,000	1,645,000	1,574,000	1,386,000	1,480,000	1,339,000	1,316,000	1,250,000	1,354,000	1,275,000	1,384,000	1,268,000	1,254,000	1,216,000	1,234,000	1,878,000	1,436,000	1,451,000	1,377,000	1,240,000	1,579,000	1,308,000	1,154,000	1,174,000	1,157,000	976,000	775,000	646,000	561,000	668,000	426,000	403,000	364,000	256,000	439,000	302,000	258,000	235,000	215,000	174,000	61,000	40,000	23,000	20,000	19,000	24,000	48,000
research and development	66,265,000	64,856,000	68,846,000	60,471,000	60,735,000	70,300,000	59,336,000	58,745,000	58,505,000	54,707,000	45,517,000	43,277,000	40,851,000	36,754,000	33,292,000	32,825,000	28,120,000	28,519,000	28,091,000	28,232,000	29,022,000	28,275,000	33,869,000	26,497,000	26,123,000	24,312,000	22,805,000	21,656,000	20,244,000	18,794,000	18,860,000	20,543,000	17,050,000	13,631,000	11,693,000	7,876,000	7,176,000	6,484,000	7,054,000	5,672,000	4,634,000	-11,329,161	3,612,000	3,341,000	4,377,000	3,789,000	3,047,000	4,252,000	7,285,000	6,567,000	5,155,000	4,491,000	4,257,000	4,856,000	3,008,000	2,668,000	3,542,000	3,542,000	5,610	110	267		5,551	5,325	5,446	5,401	5,401	63	5,078	5,211	68	5,211	5,077	4,811	70	4,876	4,876	64	4,595	4,680	56	4,680	29	4,076	103	4,348	4,348	4,189	4,064	53	-194		74	84,773	-140,481	117,140	141,002
selling, general and administrative	145,356,000	130,237,000	123,977,000	103,851,000	90,660,000	83,372,000	73,745,000	66,935,000	56,268,000	47,152,000	45,262,000	43,281,000	48,564,000	42,323,000	35,163,000	37,813,000	37,549,000	32,285,000	30,533,000	30,029,000	29,509,000	25,696,000	26,523,000	25,572,000	27,535,000	27,131,000	24,245,000	24,591,000	24,389,000	21,560,000	21,308,000	19,981,000	18,440,000	16,795,000	16,471,000	14,113,000	15,037,000	11,760,000	10,931,000	12,118,000	10,432,000	-28,080,826	9,291,000	9,342,000	9,453,000	8,044,000	9,103,000	7,965,000	9,805,000	7,517,000	7,179,000	8,160,000	8,383,000	6,482,000	5,694,000	5,751,000	7,487,000	7,487,000
total operating expenses	214,504,000	197,638,000	197,419,000	167,755,000	153,798,000	156,628,000	135,948,000	128,204,000	117,308,000	103,736,000	92,424,000	88,132,000	90,801,000	80,557,000	69,794,000	71,954,000	66,919,000	62,158,000	59,899,000	59,645,000	59,799,000	55,225,000	61,608,000	53,303,000	55,536,000	52,879,000	48,501,000	47,624,000	45,873,000	41,933,000	41,476,000	41,678,000	36,664,000	31,583,000	29,140,000	22,764,000	22,859,000	18,805,000	18,653,000	18,216,000	15,469,000	13,316,000	13,159,000	13,122,000	14,132,000	12,091,000	12,385,000	12,432,000	17,264,000	14,145,000	12,374,000	12,674,000	12,660,000	11,357,000	8,726,000	8,467,000	11,029,000	11,029,000	192,338,000	6,437,000	8,869,000		189,507,000	162,797,000	174,587,000	167,482,000	167,482,000	6,064,000	139,857,000	149,810,000	4,888,000	149,810,000	140,252,000	120,956,000	4,968,000	123,566,000	123,566,000	4,083,000	106,489,000	110,378,000	1,953,000	110,378,000	2,736,000	80,258,000	6,549,000	91,458,000	91,458,000	83,294,000	60,541,000	5,481,000	4,386,000		5,787,000	5,522,394	4,257,966	3,694,446	2,570,029
income from operations	-49,601,000	4,487,000	10,219,000	26,675,000	3,416,000	25,262,000	46,598,000	35,592,000	29,500,000	31,669,000	31,177,000	29,583,000	14,853,000	22,499,000	31,934,000	31,432,000	26,769,000	36,664,000	36,232,000	31,943,000	19,638,000	30,510,000	24,719,000	35,262,000	37,711,000	35,016,000	33,004,000	24,633,000	18,956,000	24,898,000	22,969,000	20,634,000	20,995,000	21,697,000	13,623,000	12,795,000	4,740,000	5,007,000	3,072,000	1,508,000	592,000	1,651,000	102,000	-1,166,000	-4,030,000	-3,077,000	-5,103,000	-6,581,000	-12,859,000	-10,030,000	-9,740,000	-10,783,000	-10,943,000	-9,980,000	-7,671,000	-7,592,000	-11,029,000	-11,029,000	-191,324,000	-6,437,000	-8,869,000		-188,493,000	-161,783,000	-173,573,000	-166,468,000	-166,468,000	-6,064,000	-138,872,000	-148,796,000	-4,882,000	-148,796,000	-139,243,000	-120,037,000	-4,902,000	-122,790,000	-122,790,000	-4,083,000	-106,195,000	-109,602,000	-1,579,000	-109,602,000	-2,628,000	-80,185,000	-6,549,000	-91,237,000	-91,237,000	-83,173,000
yoy	-1552.02%	-82.24%	-78.07%	-25.05%	-88.42%	-20.23%	49.46%	20.31%	98.61%	40.76%	-2.37%	-5.88%	-44.51%	-38.63%	-11.86%	-1.60%	36.31%	20.17%	46.58%	-9.41%	-47.93%	-12.87%	-25.10%	43.15%	98.94%	40.64%	43.69%	19.38%	-9.71%	14.75%	68.60%	61.27%	342.93%	333.33%	343.46%	748.47%	700.68%	203.27%	2911.76%	-229.33%	-114.69%	-153.66%	-102.00%	-82.28%	-68.66%	-69.32%	-47.61%	-38.97%	17.51%	0.50%	26.97%	42.03%	-0.78%	-9.51%	-95.99%	17.94%	24.35%		1.50%	-96.02%	-94.89%		13.23%	2567.93%	24.99%	11.88%	3309.83%	-95.92%	-0.27%	23.96%	-0.41%	21.18%	13.40%	2839.92%	-95.38%	12.03%	7676.44%	-96.27%	3940.91%	36.69%	-75.89%	20.13%	-97.12%	-3.59%
qoq	-1205.44%	-56.09%	-61.69%	680.88%	-86.48%	-45.79%	30.92%	20.65%	-6.85%	1.58%	5.39%	99.17%	-33.98%	-29.55%	1.60%	17.42%	-26.99%	1.19%	13.43%	62.66%	-35.63%	23.43%	-29.90%	-6.49%	7.70%	6.10%	33.98%	29.95%	-23.87%	8.40%	11.32%	-1.72%	-3.24%	59.27%	6.47%	169.94%	-5.33%	62.99%	103.71%	154.73%	-64.14%	1518.63%	-108.75%	-71.07%	30.97%	-39.70%	-22.46%	-48.82%	28.21%	2.98%	-9.67%	-1.46%	9.65%	30.10%	1.04%	-31.16%	0.00%	-94.24%	2872.25%	-27.42%			16.51%	-6.79%	4.27%	0.00%	2645.18%	-95.63%	-6.67%	2947.85%	-96.72%	6.86%	16.00%	2348.74%	-96.01%	0.00%	2907.35%	-96.16%	-3.11%	6841.23%	-98.56%	4070.55%	-96.72%	1124.39%	-92.82%	0.00%	9.70%
interest and other income	4,886,000	5,423,000	5,024,000	5,017,000	6,202,000	6,698,000	6,345,000	6,004,000	5,493,000	5,140,000	5,208,000	3,347,000	3,581,000	1,777,000	1,070,000	630,000	80,000	72,000	72,000	110,000	275,000	297,000	622,000	1,010,000	1,471,000	1,444,000	1,348,000	1,178,000	1,097,000	1,042,000	759,000	562,000	294,000	-59,250	86,000																								6,822,000	3,000	-1,000		6,824,000	6,814,000	5,335,000	5,332,000	5,332,000	2,000	5,229,000	5,322,000	6,000	5,322,000	5,311,000	4,478,000	291,000	4,737,000	4,737,000	157,000	3,829,000	4,047,000	164,000	4,047,000	96,000	2,985,000	154,000	3,329,000	3,329,000	3,126,000	2,032,000	278,000	282,000		283,000	268,816	169,201	115,913	24,308
income before income taxes	-44,715,000	9,910,000	15,243,000	31,692,000	9,618,000	31,960,000	52,943,000	41,596,000	34,993,000	36,809,000	36,385,000	32,930,000	18,434,000	24,276,000	33,004,000	32,062,000	26,849,000	36,736,000	36,304,000	32,053,000	19,913,000	30,807,000	25,341,000	36,272,000	39,182,000	36,460,000	34,352,000	25,811,000	20,053,000	25,940,000	23,728,000	21,196,000	21,289,000	21,885,000	13,709,000	12,697,000	4,515,000
income tax benefit	12,954,000	14,378,000	4,425,000	3,457,000	10,929,000					-3,240,750	-5,007,000			-1,774,500	1,604,000		-4,052,000				3,552,000									-3,202,750	-5,981,000			76,445,000	48,000
net income	-31,761,000	24,288,000	19,668,000	35,149,000	20,547,000	30,746,000	47,213,000	35,488,000	27,762,000	31,355,000	31,378,000	27,528,000	15,879,000	16,601,000	34,608,000	27,412,000	22,797,000	32,053,000	30,471,000	26,523,000	23,465,000	25,994,000	21,625,000	28,327,000	30,065,000	29,381,000	26,340,000	20,186,000	18,274,000	22,008,000	17,747,000	18,196,000	17,459,000	98,330,000	13,757,000	12,647,000	4,388,000																													-162,006,000	-162,006,000	-6,073,000	-135,242,000	-145,068,000	-4,878,000	-145,068,000	-135,522,000	-116,182,000	-5,565,000	-118,336,000	-118,336,000	-3,930,000	-102,631,000	-105,818,000	-1,417,000	-105,818,000	-2,535,000	-77,442,000	-6,403,000	-88,159,000	-88,159,000	-80,295,000	-58,719,000	-5,223,000	-4,111,000		-5,512,000	-5,311,046	-4,088,765	-3,583,741	-2,550,929
yoy	-254.58%	-21.00%	-58.34%	-0.96%	-25.99%	-1.94%	50.47%	28.92%	74.83%	88.87%	-9.33%	0.42%	-30.35%	-48.21%	13.58%	3.35%	-2.85%	23.31%	40.91%	-6.37%	-21.95%	-11.53%	-17.90%	40.33%	64.52%	33.50%	48.42%	10.94%	4.67%	-77.62%	29.00%	43.88%	297.88%																																	11.68%	3221.16%	-95.81%	-0.21%	24.86%	-12.35%	22.59%	14.52%	2856.28%	-94.58%	11.83%	8251.16%	-96.29%	3948.56%	36.64%	-77.87%	20.03%	-97.12%	-3.55%	-89.10%	1587.90%	2044.47%		965.29%	-1.66%	0.54%		116.08%
qoq	-230.77%	23.49%	-44.04%	71.07%	-33.17%	-34.88%	33.04%	27.83%	-11.46%	-0.07%	13.99%	73.36%	-4.35%	-52.03%	26.25%	20.24%	-28.88%	5.19%	14.89%	13.03%	-9.73%	20.20%	-23.66%	-5.78%	2.33%	11.55%	30.49%	10.46%	-16.97%	24.01%	-2.47%	4.22%	-82.24%	614.76%	8.78%	188.22%																														0.00%	2567.64%	-95.51%	-6.77%	2873.92%	-96.64%	7.04%	16.65%	1987.73%	-95.30%	0.00%	2911.09%	-96.17%	-3.01%	7367.75%	-98.66%	4074.28%	-96.73%	1109.46%	-92.74%	0.00%	9.79%	36.74%	1024.24%	27.05%			3.78%	29.89%	14.09%	40.49%
net income attributable to common stockholders	-31,202,000	23,904,000	19,359,000	34,611,000	20,288,000	30,389,000	46,690,000	35,120,000	27,514,000	31,143,000	31,172,000	27,356,000	15,807,000	16,533,000	34,550,000	27,398,000
basic net income per common share	-300	240	190	330	190	290	450	340	270	300	310	270	150	150	320	260																		870	120	110
diluted net income per common share	-300	200	160	290	170	250	410	320	250	280	280	250	140	140	300	240																		790	110	100
weighted-average shares outstanding used in computing net income per common share
basic	104,435,000	103,862,000	103,545,000	104,111,000	104,106,000	103,232,000	103,371,000	103,118,000	102,791,000	103,560,000	102,014,000	101,964,000	107,885,000	106,787,000	107,125,000	106,289,000	106,012	115,653	115,791	116,294	116,818	115,412	115,734	115,006	114,575	114,349	113,875	114,340	114,844	115,343	115,798	115,492	114,882	113,527	113,603	113,249	112,867	110,566	110,652	110,034
diluted	104,435,000	119,987,000	119,439,000	120,485,000	119,819,000	113,480,000	113,723,000	111,244,000	109,915,000	111,742,000	111,099,000	109,590,000	115,425,000	115,966,000	116,620,000	115,399,000	115,037	125,963	125,136	126,680	129,668	124,194	124,464	123,234	122,226	122,566	121,762	121,783	123,895	126,688	126,159	127,515	127,733	124,515	125,651	123,011	121,189	116,139	116,419	115,329
income tax expense						-1,214,000	-5,730,000	-6,108,000	-7,231,000			-5,402,000	-2,555,000			-4,650,000		20,305,000	-5,833,000	-5,530,000		46,369,000	-3,716,000	-7,945,000	-9,117,000	37,911,000	-8,012,000	-5,625,000	-1,779,000			-3,000,000	-3,830,000
other comprehensive income:
unrealized loss on available-for-sale investments, net of tax effect of 323 and 61, respectively																	-1,019,000
foreign currency translation gain, net of tax																	-105,000	14,000	-77,000	16,000	26,000
total comprehensive income																	21,673,000	31,711,000	30,371,000	26,489,000	23,299,000	25,832,000	21,362,000	28,857,000	30,114,000	29,328,000	26,333,000	20,413,000	18,438,000	22,090,000	17,797,000	18,221,000	17,307,000	98,269,000	13,760,000	12,642,000	4,376,000
basic net income per share																	0.22	0.28	0.26	0.23	0.2	0.22	0.19	0.25	0.26	0.25	0.23	0.18	0.16	0.19	0.15	0.16	0.15
diluted net income per share																	0.2	0.26	0.24	0.21	0.18	0.2	0.17	0.23	0.25	0.24	0.22	0.17	0.15	0.18	0.14	0.14	0.14
weighted-average shares outstanding used in computing net income per share
basic	104,435,000	103,862,000	103,545,000	104,111,000	104,106,000	103,232,000	103,371,000	103,118,000	102,791,000	103,560,000	102,014,000	101,964,000	107,885,000	106,787,000	107,125,000	106,289,000	106,012	115,653	115,791	116,294	116,818	115,412	115,734	115,006	114,575	114,349	113,875	114,340	114,844	115,343	115,798	115,492	114,882	113,527	113,603	113,249	112,867	110,566	110,652	110,034
diluted	104,435,000	119,987,000	119,439,000	120,485,000	119,819,000	113,480,000	113,723,000	111,244,000	109,915,000	111,742,000	111,099,000	109,590,000	115,425,000	115,966,000	116,620,000	115,399,000	115,037	125,963	125,136	126,680	129,668	124,194	124,464	123,234	122,226	122,566	121,762	121,783	123,895	126,688	126,159	127,515	127,733	124,515	125,651	123,011	121,189	116,139	116,419	115,329
net unrealized gain on available-for-sale investments, net of tax effect of 8, 109, 85 and (81), respectively																		-66,250	-23,000
net unrealized gain on available-for-sale investments, net of tax effect of 16, (170), 77 and (190), respectively																				-50,000
net unrealized gain on available-for-sale investments, net of tax effect of 61 and (20), respectively																					-192,000
net unrealized gain on available-for-sale investments, net of tax impact of 109, 1, (81) and (123), respectively																						64,750	-347,000
foreign currency translation loss, net of tax																						14,250	84,000	-15,000	-12,000	-1,250	-5,000
net unrealized gain on available-for-sale investments, net of tax impact of (170), (73), (190) and (124), respectively																								545,000
net unrealized gain on available-for-sale investments, net of tax impact of (20) and (52), respectively																									61,000
net unrealized income on available-for-sale investments, net of tax impact of 1, (16), (123) and 25, respectively																										97,250	-2,000
net unrealized income on available-for-sale investments, net of tax impact of (73), , (124) and 41, respectively																												227,000
net unrealized income on available-for-sale investments, net of tax impact of (52) and 48, respectively																													164,000
net unrealized income on available-for-sale investments, net of tax impact of (16), 0, 25 and 0, respectively																														-19,250	50,000
other comprehensive loss:
net unrealized income on available-for-sale investments, net of tax impact of , 0, 41 and 0, respectively																																25,000
net unrealized loss on available-for-sale investments, net of tax impact of 48 and 0, respectively																																	-152,000
net unrealized gain on available-for-sale investments																																		-3,500	3,000
interest and other expense																																				-98,000	-225,000	-410,000	-487,000	-531,000	-611,000	-568,250	-703,000	-770,000	-800,000	-818,000	-903,000	-971,000	-1,071,000	-1,094,000	-1,166,000	-1,114,000	-1,141,000	-1,144,000	-622,000
provision for income taxes																																				-50,000	-127,000
net unrealized loss on available-for-sale investments																																				-5,000	-12,000
basic and diluted net income per common share																																					40	40	20	10
net income and comprehensive income																																						4,597,000	2,585,000	977,000		-1,841,750	-601,000
net loss and comprehensive loss																																									-19,000			-1,936,000	-4,830,000	-3,895,000	-6,006,000	-7,552,000	-13,930,000	-11,124,000	-10,906,000	-11,897,000	-12,084,000	-11,124,000	-8,293,000	-7,597,000		-11,034,000	-5,604,500	-6,435,000	-8,882,000		-183,305,000	-4,718,250	-169,111,000
basic and diluted net loss per share																																												-0.02	-0.05	-0.04	-0.06	-0.07	-0.14	-0.11	-0.11	-0.12	-0.12	-0.11	-0.08	-0.09		-0.13	-0.068	-0.08	-0.11			-0.07				-0.1	-0.075		-0.1			-0.075	-0.11			-0.1	-0.058		-0.04		-0.1	-0.233	-0.28				-0.165	-0.23	-0.18		-0.24	-0.24	-0.18	-0.18	-0.28
weighted-average shares outstanding used in computing basic and diluted net loss per share																																									109,661			107,874	101,905		101,134	100,980	100,521		99,814	99,814	99,814		99,082	88,621		84,420		84,188	84,010							62,655			49,763				48,754			40,235
basic and diluted net income per share																																										-0.018	-0.01														-0.13
weighted-average shares outstanding used in computing basic and diluted net income per share																																											108,461														84,420
product sales																																														9,014,000	7,282,000	5,851,000	4,405,000	4,115,000	2,634,000	1,891,000	1,717,000	1,377,000	1,055,000	875,000
other expense																																																								-5,000		-5,000	-1,638,000	-1,000	-12,000		-1,636,000	-1,612,000	-1,623,000	-1,620,000		-11,000	-1,599,000	-1,594,000	-2,000		-1,590,000	-623,000	-954,000	-283,000		-4,000	-265,000	-263,000	-2,000		-3,000	-242,000	-8,000	-251,000		-248,000	-210,000	-20,000
collaboration revenue																																																															1,014,000		1,014,000	1,014,000	1,014,000		985,000	1,014,000	6,000	1,014,000	1,009,000	919,000	66,000	776,000	776,000		294,000	776,000	374,000	776,000	108,000	73,000		221,000	221,000	121,000
other income																																																									-5,000										-1,620,000					-1,594,000					-283,000					-263,000					-251,000
net income and comprehensive loss																																																									-11,034,000
research and development*																																																											139,806,000	3,228,000	6,203,000		138,084,000	118,875,000	128,498,000	123,274,000	123,274,000	4,489,000	103,558,000	110,462,000	3,342,000	110,462,000	103,993,000	90,383,000	3,300,000	91,783,000	91,783,000	2,850,000	80,469,000	82,985,000	1,160,000	82,985,000	1,601,000	59,885,000	5,147,000	69,728,000	69,728,000	62,746,000	44,402,000	4,521,000	3,325,000		4,714,000	4,306,513	3,098,255	2,569,419	1,576,584
general and administrative*																																																											52,532,000	3,209,000	2,666,000		51,423,000	43,922,000	46,089,000	44,208,000	44,208,000	1,575,000	36,299,000	39,348,000	1,546,000	39,348,000	36,259,000	30,573,000	1,668,000	31,783,000	31,783,000	1,233,000	26,020,000	27,393,000	793,000	27,393,000	1,135,000	20,373,000	1,402,000	21,730,000	21,730,000	20,548,000	16,139,000	960,000	1,061,000		1,073,000	1,215,881	1,159,711	1,125,027	993,445
* includes non-cash stock-based compensation consisting of the following:
general and administrative																																																											12,375	844	602		11,982	10,097	10,922	10,422	10,422	421	8,404	9,167	399	9,167	8,369	6,987	328	7,344	7,344	350	6,239	6,215	-108	6,215	221	5,001	274	5,320	5,320	5,071	4,145	180	213		253	289,664	354,803	439,992	390,490
total non-cash stock-based compensation																																																											17,985	954	869		17,533	15,422	16,368	15,823	15,823	484	13,482	14,378	467	14,378	13,446	11,798	398	12,220	12,220	414	10,834	10,895	-52	10,895	250	9,077	377	9,668	9,668	9,260	8,209	233	19		327	374,437	214,322	557,132	531,492
legal settlement																																																																187,500	750,000	750,000	750,000
*includes non-cash stock-based compensation consisting of the following:
shares used in computing basic and diluted net loss per share																																																																															8,116.5		34,742		25,932	5,672.75	22,719				5,649.25	22,621	22,594		22,576	1,381,915	22,532,466	19,777,534	8,959,753
shares used in computing basic and diluted net income per share
______________ * includes non-cash stock-based compensation expense (recovery) consisting of the following:
_______________ *includes non-cash stock-based compensation consisting of the following:
*includes non-cash stock-based compensation of the following:
non-operating expense																																																																																											-7,000		-8,000
interest expense																																																																																														-2,604		-5,208	-5,208
* includes non-cash stock-based compensation expense (credits) of the following
* includes non-cash stock-based compensation expense (credits) of the following:
* includes non-cash stock-based compensation of the following:

Balance Sheets:

Quarterly

Annual

Unit: USD	2026-03-31	2025-12-31	2025-09-30	2025-06-30	2025-03-31	2024-12-31	2024-09-30	2024-06-30	2024-03-31	2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2017-06-30	2017-03-31	2016-12-31	2016-09-30	2016-06-30	2016-03-31	2015-12-31	2015-09-30	2015-06-30	2015-03-31	2014-12-31	2014-09-30	2014-06-30	2014-03-31	2013-12-31	2013-09-30	2013-06-30	2013-03-31	2012-12-31	2012-09-30	2012-06-30	2012-03-31	2011-12-31	2011-09-30	2011-06-30	2011-03-31	2010-12-31	2010-09-30	2010-06-30	2010-03-31	2009-12-31	2009-09-30	2009-06-30	2009-03-31	2008-12-31	2008-09-30	2008-06-30	2008-03-31	2007-12-31	2007-09-30	2007-06-30	2007-03-31	2006-12-31	2006-09-30	2006-06-30	2006-03-31	2005-12-31	2005-09-30	2005-06-30	2005-03-31	2004-12-31	2004-09-30	2004-06-30	2004-03-31

assets
current assets:
cash and cash equivalents	108,738,000	120,495,000	125,138,000	102,745,000	89,819,000	127,665,000	137,289,000	128,588,000	149,750,000	135,551,000	111,800,000	172,377,000	299,942,000	66,329,000	50,243,000	35,346,000	61,862,000	77,617,000	94,688,000	95,430,000	52,381,000	76,190,000	30,560,000	58,523,000	84,477,000	31,269,000	44,948,000	58,141,000	49,650,000	41,625,000	33,894,000	31,165,000	33,121,000	31,062,000	31,060,000	33,623,000	37,976,000	51,536,000	47,865,000	41,789,000	40,744,000	40,435,000	36,450,000	37,048,000	37,953,000	24,248,000	26,780,000	33,974,000	43,618,000	54,877,000	63,175,000	72,220,000	81,460,000	93,032,000	101,628,000	34,899,000	42,627,000	39,635,000	45,909,000	52,230,000	59,201,000	24,578,000	28,976,000	35,385,000	18,548,000	23,867,000	10,716,000	14,447,000	19,194,000	14,716,000	16,320,000	26,123,000	31,791,000	11,433,000	18,565,000	11,949,000	14,744,000	8,906,000	3,296,000	3,819,000	2,132,000	3,816,000	1,412,000	2,826,000	3,501,000	5,930,117	22,023,562	35,235,142	8,993,337
short-term marketable securities	229,446,000	251,657,000	296,545,000	239,481,000	232,944,000	255,669,000	243,047,000	344,568,000	261,011,000	232,670,000	243,425,000	190,885,000	165,115,000	365,343,000	346,019,000	334,740,000	283,665,000	145,918,000	266,643,000	274,552,000	320,578,000	364,506,000	398,233,000	346,835,000	222,838,000	244,693,000	186,697,000	143,396,000	137,255,000	165,135,000	161,300,000	128,780,000	92,241,000	57,682,000	44,096,000	32,542,000	14,798,000
trade receivables, net of allowance	39,072,000	59,786,000	69,629,000	64,567,000	61,819,000	53,976,000	59,717,000	53,837,000	61,518,000	41,123,000	34,626,000	32,553,000	32,557,000	31,057,000	29,414,000	28,164,000	27,178,000	27,625,000	26,508,000	27,620,000	22,200,000	26,198,000	21,957,000	22,725,000	26,684,000	19,928,000	22,405,000	19,774,000	19,218,000	17,588,000	19,360,000	28,704,000	17,261,000	15,300,000	11,872,000	9,504,000	9,214,000	9,860,000
inventory	12,890,000	12,868,000	12,349,000	12,276,000	14,368,000	12,412,000	8,050,000	8,350,000	7,190,000	7,730,000	7,513,000	6,915,000	6,409,000	6,100,000	6,046,000	5,437,000	5,079,000	4,988,000	4,994,000	4,669,000	4,948,000	4,910,000	4,817,000	4,927,000	5,084,000	5,424,000	5,462,000	5,142,000	5,000,000	4,732,000	5,362,000	4,947,000	4,876,000	4,576,000	3,828,000	3,089,000	2,888,000	2,329,000	2,327,000	2,134,000	1,912,000	1,682,000	1,604,000	1,451,000	1,310,000	1,207,000	1,080,000	1,072,000	1,127,000	1,096,000	1,025,000	694,000	1,026,000	853,000	1,837,000	2,437,000	56,000
prepaid expenses and other current assets	35,887,000	40,658,000	37,469,000	24,043,000	39,553,000	21,880,000	18,875,000	25,503,000	23,898,000	27,562,000	20,163,000	15,858,000	15,870,000	16,424,000	20,680,000	15,358,000	10,436,000	10,315,000	9,067,000	8,999,000	9,517,000	6,697,000	7,926,000	5,323,000	5,693,000	6,044,000	7,798,000	6,202,000	5,741,000	7,740,000	4,275,000	3,579,000	3,324,000	2,669,000	3,086,000	2,527,000	1,799,000	1,964,000	1,353,000	1,554,000	1,106,000	642,000	1,180,000	1,241,000	622,000	1,441,000	1,769,000	2,166,000	1,453,000	910,000	1,004,000	801,000	572,000	620,000	800,000	608,000	102,000	140,000	427,000	455,000	604,000	418,000	613,000	621,000	581,000	553,000	686,000	974,000	328,000	1,270,000	1,690,000	1,638,000	561,000	290,000	430,000	887,000	368,000	343,000	500,000	598,000	1,550,000	425,000	830,000	1,317,000	797,000	838,114	672,859	878,689	347,940
total current assets	426,033,000	485,464,000	541,130,000	443,112,000	438,503,000	471,602,000	466,978,000	560,846,000	503,367,000	458,636,000	431,527,000	432,588,000	533,893,000	499,253,000	452,402,000	419,045,000	388,220,000	266,463,000	401,900,000	411,270,000	409,624,000	478,501,000	463,493,000	438,333,000	344,776,000	307,358,000	267,310,000	232,655,000	216,864,000	236,820,000	224,191,000	197,175,000	150,823,000	124,185,000	93,942,000	81,285,000	66,675,000	65,689,000	59,781,000	54,778,000	50,514,000	48,980,000	45,179,000	44,691,000	44,186,000	30,230,000	32,375,000	39,437,000	48,120,000	58,311,000	66,223,000	74,570,000	84,201,000	95,062,000	104,619,000	38,299,000	42,785,000	39,775,000	46,336,000	52,685,000	59,805,000	24,996,000	29,589,000	36,006,000	19,129,000	24,420,000	11,402,000	15,421,000	20,972,000	19,579,000	24,514,000	27,761,000	32,352,000	17,656,000	21,012,000	12,836,000	15,112,000	9,799,000	12,534,000	18,058,000	25,490,000	29,505,000	30,641,000	33,655,000	33,077,000	38,239,247	49,578,886	52,912,316	9,341,277
strategic inventory	14,506,000	11,094,000	12,002,000	7,991,000	1,166,000	3,583,000	7,764,000	8,451,000	7,846,000	8,244,000	8,752,000	8,762,000	10,156,000	10,931,000	11,027,000	11,978,000	13,098,000	12,962,000	13,659,000	14,734,000	15,384,000	16,247,000	12,075,000	11,193,000	11,063,000	11,981,000	11,539,000	12,726,000	10,360,000	11,510,000	7,360,000	5,500,000	2,910,000	3,800,000	1,680,000	3,210,000	3,820,000	2,835,000	2,980,000	1,960,000	2,280,000	2,800,000	2,990,000	3,420,000	3,730,000	4,090,000	4,430,000	4,570,000	4,330,000	4,450,000	4,530,000	4,850,000	3,650,000	3,810,000	640,000
operating lease right-of-use asset	7,196,000	4,583,000	4,776,000	4,964,000	5,147,000	5,324,000	5,503,000	5,684,000	61,000	120,000	178,000	235,000	575,000	1,143,000	1,707,000	2,264,000	2,816,000	514,000	1,022,000	1,524,000	2,020,000	2,509,000	2,993,000	3,472,000	3,082,000	3,446,000	742,000	1,106,000	1,465,000
property and equipment	3,171,000	1,890,000	2,094,000	2,348,000	2,543,000	2,689,000	2,930,000	1,472,000	127,000	195,000	302,000	413,000	461,000	633,000	801,000	862,000	726,000	1,002,000	1,226,000	1,414,000	1,481,000	1,675,000	1,311,000	619,000	880,000	1,050,000	1,227,000	1,177,000	925,000	655,000	540,000	552,000	577,000	518,000	553,000	499,000	302,000	205,000	145,000	76,000	93,000	98,000	143,000	173,000	230,000	236,000	273,000	296,000	285,000	203,000	184,000	139,000	154,000	150,000	105,000	59,000	30,000	26,000	3,000	3,000	4,000	4,000	4,000	5,000	7,000	10,000	12,000	15,000	17,000	20,000	15,000	18,000	22,000	25,000	28,000	32,000	35,000	38,000	42,000	45,000	49,000	52,000	55,000	50,000
long-term marketable securities	177,261,000	160,270,000	102,557,000	172,775,000	248,041,000	219,831,000	167,310,000	19,315,000	40,276,000	57,176,000	59,621,000			4,947,000	4,895,000	11,890,000	22,566,000	112,277,000	133,845,000	101,657,000	81,834,000	36,196,000	15,425,000	4,200,000	41,690,000	39,352,000	35,250,000	24,165,000	28,842,000		1,481,000		15,010,000	15,281,000	1,508,000	1,494,000	4,493,000
other assets	5,153,000	5,153,000	8,049,000	8,303,000	6,610,000	6,610,000	6,973,000	6,939,000	6,388,000	6,541,000	6,540,000	4,413,000	4,764,000	5,058,000	5,081,000	1,834,000	2,984,000	3,083,000	4,106,000	4,140,000	5,030,000	5,000,000	5,010,000	4,536,000	3,441,000	3,448,000	150,000	150,000	75,000	50,000	53,000	53,000	73,000	50,000	12,989,000	49,000	49,000	24,000	24,000	24,000	25,000	59,000	65,000	71,000	78,000	74,000	81,000	87,000	96,000	113,000	120,000	128,000	136,000	144,000	160,000	260,000	72,000	32,000	40,000	32,000	28,000	104,000	95,000	86,000	80,000	81,000	206,000	174,000	180,000	176,000	170,000	64,000	63,000	63,000	64,000	62,000	61,000	65,000	70,000	67,000	63,000	60,000	76,000	83,000	51,000	46,858	56,500	51,856	941,678
deferred tax assets	181,561,000	168,197,000	152,999,000	162,229,000	144,445,000	130,914,000	126,799,000	111,848,000	97,870,000	90,605,000	87,102,000	78,214,000	67,999,000	61,465,000	57,342,000	48,491,000	37,713,000	27,455,000	29,641,000	33,741,000	37,025,000	31,603,000	33,818,000	35,470,000	40,562,000	45,677,000	50,804,000	56,700,000	61,681,000	62,659,000	66,126,000	71,102,000	73,583,000	76,703,000
total assets	814,881,000	836,651,000	823,607,000	801,722,000	846,455,000	840,553,000	784,257,000	714,555,000	655,935,000	621,517,000	594,022,000	524,625,000	617,848,000	583,430,000	533,255,000	496,364,000	468,123,000	423,756,000	585,399,000	568,480,000	552,398,000	571,731,000	534,125,000	497,823,000	445,494,000	412,312,000	367,022,000	328,679,000	320,212,000	311,694,000	299,751,000	274,382,000	242,976,000	220,537,000	110,672,000	86,537,000	75,339,000	68,753,000	62,930,000	56,838,000	52,912,000	51,937,000	48,377,000	48,355,000	48,224,000	34,630,000	37,159,000	44,390,000	52,831,000	63,077,000	71,057,000	79,687,000	88,141,000	99,166,000	105,524,000	38,618,000	42,887,000	39,833,000	46,379,000	52,720,000	59,837,000	25,104,000	29,688,000	36,097,000	19,216,000	24,511,000	11,620,000	15,610,000	21,169,000	19,775,000	24,699,000	27,843,000	32,437,000	17,744,000	21,104,000	12,930,000	15,208,000	9,902,000	12,646,000	18,170,000	25,602,000	30,156,000	34,321,000	38,135,000	41,929,000	47,771,628	52,489,032	56,124,279	10,282,955
liabilities and stockholders’ equity
current liabilities:
accounts payable	33,306,000	40,444,000	34,446,000	23,525,000	27,947,000	15,376,000	18,584,000	19,484,000	12,557,000	17,396,000	16,710,000	7,976,000	11,216,000	11,976,000	8,178,000	8,246,000	9,269,000	6,908,000	6,558,000	9,216,000	6,969,000	10,554,000	6,510,000	6,304,000	4,976,000	7,537,000	5,937,000	7,026,000	9,330,000	8,266,000	13,922,000	6,365,000	7,850,000	8,579,000	6,226,000	2,082,000	4,253,000	2,290,000	4,309,000	2,081,000	2,082,000	1,325,000	1,740,000	2,360,000	1,036,000	1,886,000	1,960,000	2,595,000	3,666,000	2,381,000	2,337,000	3,033,000	2,263,000	3,804,000	1,574,000	4,235,000	2,084,000	3,611,000	1,066,000	2,291,000	1,865,000	817,000	1,677,000	1,173,000	1,023,000	1,270,000	892,000	670,000	1,571,000	1,304,000	1,003,000	1,098,000	878,000	1,115,000	1,666,000	306,000	809,000	916,000	2,618,000	1,265,000	1,231,000	549,000	833,000	125,000	285,000	549,516	980,479	629,765	935,788
accrued research and development expenses	34,091,000	33,954,000	28,322,000	29,049,000	25,260,000	33,868,000	27,736,000	21,972,000	24,825,000	21,330,000	21,305,000	18,607,000	13,981,000	14,573,000	13,771,000	13,803,000	13,051,000
accrued and other liabilities	80,161,000	90,603,000	108,447,000	91,073,000	88,875,000	90,700,000	79,464,000	59,250,000	59,744,000	51,628,000	69,633,000	52,179,000	39,093,000	30,799,000	29,412,000	24,744,000	32,660,000	27,665,000	24,309,000	21,514,000	17,999,000	21,186,000	18,972,000	22,631,000	19,590,000	23,269,000	21,568,000	16,437,000
short-term operating lease liability	1,627,000	1,084,000	1,050,000	1,017,000	984,000	829,000	432,000	44,000	76,000	151,000	225,000	297,000	575,000	1,143,000	1,707,000	2,264,000	2,264,000	526,000	1,046,000	1,559,000	2,067,000	2,050,000	2,034,000	2,019,000	1,571,000	1,558,000
total current liabilities	149,185,000	166,085,000	172,265,000	144,664,000	143,066,000	140,773,000	126,216,000	100,750,000	97,202,000	104,505,000	121,873,000	93,059,000	78,865,000	72,491,000	53,068,000	49,057,000	57,244,000	47,541,000	44,757,000	45,402,000	40,601,000	47,494,000	43,048,000	42,243,000	34,075,000	38,841,000	32,396,000	30,381,000	34,218,000	35,573,000	40,206,000	30,873,000	27,749,000	29,569,000	24,370,000	20,392,000	25,759,000	27,374,000	31,683,000	27,434,000	24,025,000	20,876,000	18,767,000	17,430,000	15,526,000	13,555,000	12,486,000	13,302,000	15,242,000	12,738,000	10,142,000	9,079,000	8,243,000	8,359,000	5,548,000	5,816,000	3,570,000	5,026,000	2,713,000	3,856,000	3,196,000	3,860,000	2,993,000	2,859,000	2,143,000	2,419,000	2,358,000	2,138,000	3,283,000	2,862,000	3,286,000	1,917,000	2,309,000	2,994,000	2,663,000	1,420,000	2,195,000	3,513,000	5,636,000	5,168,000	5,195,000	3,521,000	2,656,000	1,503,000	1,261,000	1,824,041	1,633,993	1,400,564	1,529,567
long-term operating lease liability	8,010,000	5,023,000	5,308,000	5,588,000	5,851,000	6,107,000	6,359,000	5,625,000									552,000					501,000	997,000	1,486,000	1,541,000	1,903,000
long-term accrued government rebates	4,367,000	2,562,000
long-term accrued income taxes payable	15,332,000	15,176,000	14,132,000	15,677,000	14,253,000	14,084,000	12,847,000	11,937,000	10,869,000	10,307,000	10,470,000	9,952,000	9,399,000	9,097,000	6,823,000	4,981,000	2,516,000
total liabilities	176,894,000	188,846,000	191,705,000	165,929,000	163,170,000	160,964,000	145,422,000	118,312,000	108,071,000	114,812,000	132,343,000	103,011,000	88,264,000	81,588,000	59,891,000	54,038,000	60,312,000	47,950,000	45,170,000	45,805,000	41,596,000	48,393,000	44,445,000	44,125,000	36,005,000	41,130,000	32,646,000	30,626,000	34,457,000	35,812,000																																				2,419,000				2,868,000			2,323,000	3,010,000	2,682,000	1,442,000	2,221,000	3,542,000	5,668,000	5,204,000	5,234,000	3,563,000	2,701,000	1,513,000		1,824,041	1,633,993	1,400,564	2,058,464
commitments and contingencies
stockholders’ equity:
preferred stock
common stock	141,000		139,000	138,000	137,000		135,000	134,000	133,000		133,000	132,000	131,000		130,000	128,000	128,000		126,000	125,000	124,000		121,000	121,000	120,000		119,000	118,000	118,000		116,000	116,000	115,000																						100,000	89,000	89,000		84,000	84,000	84,000		72,000	72,000	63,000		50,000	50,000	50,000		49,000	48,000	48,000		40,000	35,000	35,000		23,000	23,000	23,000		23,000	23,000
treasury stock	-976,688,000	-966,586,000	-923,290,000	-866,931,000	-744,692,000	-696,173,000	-682,177,000	-650,763,000	-641,059,000	-635,078,000	-631,788,000	-614,074,000	-462,507,000	-456,148,000	-453,001,000	-426,814,000	-417,448,000	-410,411,000	-194,304,000	-164,263,000	-131,855,000	-75,795,000	-63,969,000	-63,814,000	-62,979,000	-62,704,000	-59,732,000	-59,732,000	-42,312,000	-23,657,000	-8,904,000
additional paid-in capital	1,001,990,000	968,600,000	933,613,000	900,864,000	862,866,000	832,108,000	806,317,000	781,012,000	758,244,000	738,515,000	722,397,000	695,718,000	679,848,000	662,342,000	648,831,000	625,976,000	608,717,000	591,349,000	571,377,000	554,154,000	536,363,000	516,140,000	496,489,000	481,714,000	465,528,000	457,060,000	446,611,000	436,622,000	427,317,000	417,228,000	408,154,000	401,011,000	390,951,000	384,074,000	377,678,000	371,282,000	367,359,000	363,534,000	358,001,000	355,000,000	350,485,000	348,796,000	344,735,000	342,184,000	339,294,000	320,511,000	318,687,000	317,449,000	315,817,000	313,534,000	312,166,000	310,858,000	309,593,000	308,283,000	307,033,000	259,901,000	258,820,000	243,281,000	242,209,000	240,973,000	239,921,000	197,473,000	195,831,000	195,269,000	173,418,000	172,369,000	154,381,000	153,922,000	153,455,000	153,031,000	151,385,000	150,304,000	150,120,000	124,822,000	124,332,000	113,988,000	114,209,000	105,125,000	101,986,000	101,689,000	101,361,000	101,014,000	101,027,000	101,006,000	101,334,000	101,360,621	101,410,794	101,549,861	10,428,765
accumulated other comprehensive income	918,000	2,264,000	2,341,000	2,291,000	692,000	-217,000	1,571,000	84,000	258,000	609,000		45,000							115,000	215,000	249,000		577,000	840,000	310,000																																													-1,000	-28,000				1,000
retained earnings	611,626,000	643,387,000	619,099,000	599,431,000	564,282,000	543,735,000	512,989,000	465,776,000	430,288,000	402,526,000	371,171,000	339,793,000	312,265,000	296,386,000	279,785,000	245,177,000	217,765,000	194,968,000	162,915,000	132,444,000	105,921,000	82,456,000	56,462,000	34,837,000	6,510,000
total stockholders’ equity	637,987,000	647,805,000	631,902,000	635,793,000	683,285,000	679,589,000	638,835,000	596,243,000	547,864,000	506,705,000	461,679,000	421,614,000	529,584,000	501,842,000	473,364,000	442,326,000	407,811,000	375,806,000	540,229,000	522,675,000	510,802,000	523,338,000	489,680,000	453,698,000	409,489,000	371,182,000	334,376,000	298,053,000	285,755,000	275,882,000	259,545,000	243,509,000	215,227,000	190,968,000	86,302,000	66,145,000	49,580,000	41,379,000	31,247,000	25,660,000	20,168,000	18,498,000	13,477,000	11,526,000	10,572,000	-3,388,000	-1,317,000	3,452,000	9,371,000	21,017,000	30,773,000	40,371,000	51,003,000	61,777,000	71,651,000	32,802,000	39,317,000	34,807,000	43,666,000	48,864,000	56,641,000	21,244,000	26,695,000	33,238,000	17,073,000	22,092,000	9,262,000	13,471,000	17,882,000	16,907,000	21,404,000	25,914,000	30,114,000	14,734,000	18,422,000	11,488,000	12,987,000	6,360,000	6,978,000	12,966,000	20,368,000	26,593,000	31,620,000	36,622,000	40,668,000	45,947,587	50,855,039	54,723,715	-33,491,483
total liabilities and stockholders’ equity	814,881,000	836,651,000	823,607,000	801,722,000	846,455,000	840,553,000	784,257,000	714,555,000	655,935,000	621,517,000	594,022,000	524,625,000	617,848,000	583,430,000	533,255,000	496,364,000	468,123,000	423,756,000	585,399,000	568,480,000	552,398,000	571,731,000	534,125,000	497,823,000	445,494,000	412,312,000	367,022,000	328,679,000	320,212,000	311,694,000	299,751,000	274,382,000	242,976,000	220,537,000	110,672,000	86,537,000	75,339,000	68,753,000	62,930,000	56,838,000	52,912,000	51,937,000	48,377,000	48,355,000	48,224,000	34,630,000	37,159,000	44,390,000	52,831,000	63,077,000	71,057,000	79,687,000	88,141,000	99,166,000	105,524,000	38,618,000	42,887,000	39,833,000	46,379,000	52,720,000	59,837,000	25,104,000	29,688,000	36,097,000	19,216,000	24,511,000	11,620,000	15,610,000	21,169,000	19,775,000	24,699,000	27,843,000	32,437,000	17,744,000	21,104,000	12,930,000	15,208,000	9,902,000	12,646,000	18,170,000	25,602,000	30,156,000	34,321,000	38,135,000	41,929,000	47,771,628	52,489,032	56,124,279	10,282,955
preferred stock, par value 0.001 per share...
common stock, par value 0.001 per share...		140,000				136,000				133,000				131,000				127,000				122,000				120,000				117,000				115,000	114,000	113,000	113,000	113,000	111,000	110,000	110,000		109,000	108,000	108,000		101,000	101,000	101,000		100,000	100,000	100,000
insurance recovery receivable related to melucci litigation										14,000,000	14,000,000	14,000,000	14,000,000	14,000,000
accrued settlement related to melucci litigation										14,000,000	14,000,000	14,000,000	14,000,000	14,000,000
liabilities and stockholders' equity
accumulated other comprehensive loss											-234,000		-153,000	-869,000	-2,381,000	-2,141,000	-1,351,000													-70,000	-77,000	-127,000	-152,000	-75,000	-14,000	-17,000	-12,000																																										-8,000	-45,000	-76,000	-108,000	-120,000	-106,000	-152,000	-61,734	-27,757	-33,524
accrued clinical expenses																		12,442,000	12,844,000	13,113,000	13,566,000	13,704,000	15,532,000	11,289,000	7,938,000	6,477,000	4,121,000	5,770,000	4,537,000	3,521,000	5,392,000	5,397,000	3,486,000	2,247,000	1,892,000	1,511,000	1,461,000	1,467,000	1,775,000	963,000	1,094,000	1,171,000	609,000	492,000	1,358,000	336,000	276,000	1,643,000	3,380,000	3,288,000	1,963,000	1,044,000	583,000	843,000	605,000	640,000	781,000	644,000	755,000	799,000	694,000	815,000	851,000	1,123,000	692,000	709,000	955,000	978,000	1,325,000	989,000	781,000	414,000	884,000	879,000	612,000	748,000	919,000	2,224,000	2,541,000	3,550,000	3,584,000	2,521,000	1,426,000	961,000	596,000	655,488	338,960	483,917	209,127
long-term accrued income taxes																		409,000	413,000	403,000	995,000	398,000	400,000	396,000	389,000	386,000	250,000	245,000	239,000	239,000
accumulated other comprehensive gain																		-227,000				415,000				261,000	314,000	321,000	94,000																																													3,000
accumulated deficit																										-23,555,000	-52,936,000	-79,276,000	-99,462,000	-117,736,000	-139,744,000	-157,491,000	-175,687,000	-193,146,000	-291,476,000	-305,233,000	-317,880,000	-322,268,000	-326,865,000	-329,450,000	-330,427,000	-330,408,000	-331,367,000	-330,766,000	-328,830,000	-324,000,000	-320,105,000	-314,098,000	-306,547,000	-292,617,000	-281,493,000	-270,587,000	-258,690,000	-246,606,000
operating lease liability																											770,000	1,148,000	1,521,000
other accrued liabilities																													18,830,000	23,786,000	20,892,000	19,111,000	16,413,000	18,743,000	16,252,000	12,226,000	9,938,000	8,953,000	6,874,000	5,833,000	4,527,000	3,257,000	2,832,000	2,507,000	2,419,000	1,876,000	1,539,000	1,624,000	1,271,000	1,301,000	777,000	812,000	958,000	695,000	786,000	621,000	441,000		660,000	552,000	410,000		252,000	344,000	199,000		288,000	228,000	144,000		1,297,000	228,000	398,000		250,000	232,000	321,000		311,000	184,000	212,000		397,000	417,000	380,000	619,037	314,554	286,882	384,652
other receivable																																		12,896,000
debt obligation - current portion
long-term obligation - current portion																																				4,573,000	10,107,000	14,664,000	18,725,000	18,557,000	16,322,000		13,507,000	12,034,000	10,658,000	9,424,000	8,661,000	7,396,000	6,896,000	5,743,000					2,250,000
commitments
deferred revenue																																										158,000	79,000	37,000	55,000	33,000	50,000	44,000	29,000	25,000	55,000	37,000	76,000	16,000	21,000	26,000
long-term obligation, net of current portion																																								3,744,000	8,719,000	12,563,000	16,133,000	19,399,000	22,126,000	24,463,000	25,990,000	27,636,000	28,218,000	29,322,000	30,142,000	30,237,000	28,895,000	29,030,000	28,325,000
trade receivables																																							8,236,000	9,301,000	6,752,000	6,221,000	5,945,000	4,951,000	4,301,000	3,334,000	2,746,000	2,225,000	1,922,000	1,428,000	1,019,000	855,000	1,143,000	557,000	354,000	355,000
long-term obligation – current portion																																										14,965,000										3,650,000	3,900,000
stockholders' equity
preferred stock, 0.001 par value...
common stock, 0.001 par value...																																										110,000				101,000				100,000				100,000				84,000				72,000				62,000				50,000				40,000				26,000				23,000			23,000		22,687	22,687	9,335
accrued compensation																																																			510,000	503,000	463,000	351,000	312,000	294,000	264,000	238,000	232,000	214,000	227,000	1,806,000	213,000	219,000	225,000	210,000	214,000	251,000	233,000	243,000	195,000	166,000	137,000	637,000	121,000	121,000	133,000	138,000	153,000	157,000	156,000	144,000
long-term obligation—current portion																																																			4,500,000			2,650,000
accumulated deficit and comprehensive loss																																																							-235,482,000	-227,188,000
deficit accumulated during the development stage																																																									-219,592,000	-208,558,000	-198,622,000	-192,187,000	-183,305,000	-176,204,000	-169,111,000	-162,006,000	-156,311,000	-150,238,000	-145,068,000	-140,400,000	-135,522,000	-130,072,000	-123,901,000	-118,336,000	-113,941,000	-110,011,000	-105,818,000	-102,390,000	-100,973,000	-98,438,000	-94,562,000	-88,159,000	-80,295,000	-73,565,000	-68,318,000	-63,095,000	-58,984,000	-53,471,907	-48,160,861	-44,072,096	-40,488,355
other liabilities																																																										533,000				422,000				224,000				316,000				350,000				222,000				295,000
notes receivable from stockholders																																																											-5,000	-6,000	-59,000	-97,000	-97,000	-97,000	-97,000	-101,000	-101,000	-101,000	-101,000	-6,101,000	-6,101,000	-6,101,000	-6,107,000	-107,000	-111,000	-111,000	-111,000	-125,000	-168,000	-168,000	-168,000	-168,000	-184,000	-184,000	-184,000	-183,841	-246,258	-246,258	-246,258
obligations under capital lease
obligations under capital lease, short-term																																																																	4,000	6,000	9,000	11,000	10,000	10,000	10,000	11,000	12,000	13,000	14,000	13,000	13,000	13,000	13,000	12,000	12,000	12,000
short-term investments																																																																					1,450,000	3,593,000	6,504,000			5,933,000	2,017,000			550,000	8,738,000	13,641,000	21,808,000	25,264,000	28,399,000	29,512,000	28,779,000	31,471,016	26,882,465	16,798,485
obligations under capital lease, long-term																																																																				1,000	4,000	6,000	9,000	12,000	14,000	16,000	19,000	22,000	26,000	29,000	32,000	36,000	39,000	42,000	45,000	10,000
deferred compensation																																																																								-1,000	-6,000	-13,000	-22,000	-34,000	-173,000	-228,000	-293,000	-374,000	-477,000	-603,000	-808,000	-1,022,000	-1,369,000	-1,718,246	-2,143,566	-2,496,955	-3,194,970
long-term investments																																																																																		539,000	3,549,000	4,347,000	8,801,000	9,485,523	2,853,646
10,000,000 shares authorized; no shares outstanding at december 31, 2004 or march 31, 2005
convertible note payable																																																																																									528,897
convertible preferred stock, 0.001 par value...																																																																																									41,715,974
stockholders’ equity
long-term investment																																																																																								3,160,107

Cashflow Statements:

Quarterly

Annual

Unit: USD	2026-03-31	2025-12-31	2025-09-30	2025-06-30	2025-03-31	2024-12-31	2024-09-30	2024-06-30	2024-03-31	2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2017-06-30	2017-03-31	2016-12-31	2016-09-30	2016-06-30	2016-03-31	2015-12-31	2015-09-30	2015-06-30	2015-03-31	2014-12-31	2014-09-30	2014-06-30	2014-03-31	2013-12-31	2013-09-30	2013-06-30	2013-03-31	2012-12-31	2012-09-30	2012-06-30	2012-05-13	2012-03-31	2011-12-31	2011-09-30	2011-06-30	2011-05-13	2011-03-31	2010-12-31	2010-09-30	2010-05-13	2010-03-31	2009-12-31	2009-09-30	2009-06-30	2009-05-13	2009-03-31	2008-12-31	2008-09-30	2008-05-13	2008-03-31	2007-12-31	2007-09-30	2007-03-31	2006-12-31	2006-09-30	2006-05-13	2006-03-31	2005-12-31	2005-09-30	2005-03-31	2004-12-31	2004-09-30	2004-05-13	2004-03-31

cash flows from operating activities:
net income	-31,761,000	24,288,000	19,668,000	35,149,000	20,547,000	30,746,000	47,213,000	35,488,000	27,762,000	31,355,000	31,378,000	27,528,000	15,879,000	16,601,000	34,608,000	27,412,000	22,797,000	32,053,000	30,471,000	26,523,000	23,465,000	25,994,000	21,625,000	28,327,000	30,065,000	29,381,000	26,340,000	20,186,000	18,274,000	22,008,000	17,747,000	18,196,000	17,459,000	98,330,000	13,757,000	12,647,000	4,388,000	4,597,000	2,585,000																		-11,034,000					-183,305,000									-135,522,000
adjustments to reconcile net income to net cash from operations:
stock-based compensation	23,043,000	20,768,000	22,879,000	19,023,000	21,830,000	16,796,000	16,102,000	15,207,000	13,249,000	13,065,000	12,876,000	11,858,000	11,141,000	10,521,000	10,554,000	10,606,000	10,761,000	10,810,000	10,952,000	11,068,000	10,101,000	8,430,000	8,702,000	8,489,000	7,918,000	7,610,000	7,271,000	7,736,000	6,696,000	6,266,000	6,510,000	6,017,000	4,954,000	3,832,000	3,623,000	3,205,000	2,701,000	1,957,000	1,831,000	1,657,000	1,613,000	1,493,000	1,543,000	1,568,000	1,409,000	1,387,000	1,211,000	1,225,000	1,378,000	1,313,000	1,308,000	1,265,000	1,310,000
accretion of marketable securities	-836,000		-1,005,000	-1,312,000	-1,693,000
depreciation and amortization	598,000	289,000	289,000	286,000	285,000	281,000	318,000
deferred income taxes	-13,110,000	-15,182,000	9,114,000	-17,764,000	-13,705,000	-3,858,000	-15,207,000	-13,964,000	-7,162,000	-3,672,000	-8,857,000	-10,238,000	-6,726,000	-4,467,000	-8,873,000	-10,630,000	-9,935,000	2,299,000	4,108,000	3,299,000	-5,360,000	2,311,000	1,761,000	4,922,000	5,095,000	5,146,000	5,897,000	4,908,000	926,000	3,465,000	4,960,000	2,473,000	3,169,000
changes in operating assets and liabilities:
trade receivables	20,714,000	9,843,000	-5,062,000	-2,748,000	-7,843,000	5,741,000	-5,880,000	7,681,000	-20,395,000	-6,497,000	-2,073,000	4,000	-1,500,000	-1,643,000	-1,250,000	-986,000	447,000	-1,117,000	1,112,000	-5,420,000	3,998,000	-4,241,000	768,000	3,959,000	-6,756,000	2,477,000	-2,631,000	-556,000	-1,630,000	1,772,000	9,344,000	-11,443,000	-1,961,000	-3,428,000	-2,368,000	-290,000	646,000	-1,624,000	1,065,000	-2,549,000	-531,000	-276,000	-994,000	-650,000	-967,000	-588,000	-521,000	-303,000	-494,000	-409,000	-164,000	288,000	-586,000	-203,000	1,000
inventory	-3,272,000	483,000	-3,943,000	-4,626,000	605,000	-78,000	1,081,000	-1,681,000	983,000	329,000	-544,000	922,000	558,000	125,000	419,000	818,000	-163,000	789,000	797,000	992,000	866,000	-4,208,000	-720,000	86,000	1,328,000	-390,000	889,000	-2,453,000	910,000	-3,433,000	-2,275,000	-2,661,000	590,000	-1,918,000	791,000	409,000	-1,544,000	143,000	-1,213,000	98,000	290,000	112,000	277,000	169,000	257,000	211,000	132,000	-183,000	89,000	9,000	-11,000	-868,000	-13,000	-2,186,000	-40,000	-2,381,000	-56,000	-56,000
prepaid expenses and other current assets	4,736,000	-3,224,000	-13,461,000	11,293,000	-13,525,000	-3,040,000	6,594,000	-1,744,000	3,612,000					4,285,000	-5,322,000	-5,034,000	-9,000	-1,309,000	-241,000			1,229,000	-2,603,000	370,000	351,000	1,754,000	-1,596,000	-461,000	1,999,000	-3,465,000	-696,000	-275,000	-635,000	417,000	-559,000	-728,000	165,000	-643,000	105,000	-320,000	-464,000	538,000	61,000	-619,000	819,000	328,000	397,000	-713,000	-543,000	94,000	-203,000	-229,000	48,000	180,000	-192,000	-506,000	38,000	38,000	-131,000	28,000	567,000	-604,000	-604,000	195,000	8,000	-40,000	-581,000	133,000	288,000	-646,000	-328,000	-328,000	420,000	-52,000	-1,077,000	-561,000	140,000	114,000	-368,000	157,000	98,000	952,000	-1,550,000	-433,000	487,000	41,000		205,830	-530,749	-347,940
accounts payable	-7,644,000	5,998,000	10,921,000	-4,780,000	12,929,000	-3,864,000	-113,000	6,590,000	-4,861,000	995,000	8,585,000	-3,153,000	-649,000	4,242,000	-165,000	-1,576,000	2,256,000	364,000	-2,657,000	2,189,000	-3,493,000	4,149,000	263,000	1,349,000	-2,600,000	1,689,000	-1,125,000	-2,252,000	953,000	-5,732,000	7,557,000	-1,455,000	-759,000	2,367,000	4,138,000	-2,179,000	1,963,000	-2,019,000	2,228,000	-1,000	757,000	-415,000	-620,000	1,324,000	-850,000	-74,000	-635,000	-1,071,000	1,285,000	44,000	-696,000	770,000	-1,541,000	2,230,000	-2,661,000	2,151,000	-1,527,000	-1,527,000	3,362,000	-1,225,000	-391,000	1,865,000	1,865,000	-860,000	504,000	150,000	1,023,000	378,000	222,000	-901,000	1,571,000	1,571,000	301,000	-95,000	220,000	878,000	-551,000	2,276,000	809,000	-1,702,000	1,353,000	34,000	1,231,000	266,000	708,000	-265,000		350,714	136,742	493,023
accrued research and development expenses	137,000	5,632,000	-727,000	3,789,000	-8,608,000	6,132,000	5,764,000	-2,852,000	3,494,000	25,000	2,698,000	4,626,000	-592,000	802,000	-32,000	752,000	609,000
accrued and other liabilities, current and non-current	-9,377,000
net cash from operating activities	-16,772,000	38,448,000	54,481,000	43,939,000	5,128,000	59,300,000	73,829,000	41,182,000	23,756,000	5,887,000	52,909,000	42,286,000	25,957,000	33,388,000	33,648,000	18,040,000	35,247,000	49,427,000	48,704,000	44,339,000	25,422,000	35,071,000	30,444,000	53,186,000	33,269,000	48,454,000	38,427,000	25,555,000	23,681,000	21,519,000	44,505,000	15,211,000	34,430,000	24,883,000	10,925,000	15,566,000	9,561,000	4,569,000	8,935,000	1,590,000	3,297,000	4,163,000	883,000	-139,000	-1,777,000	-1,403,000	-5,929,000	-8,984,000	-11,060,000	-7,666,000	-8,602,000	-9,236,000	-11,554,000	-8,742,000	-9,229,000	-7,892,000	-10,157,000	-10,157,000	-160,463,000	-6,604,000	146,962,000	-161,464,000	-161,464,000	-5,455,000	-6,426,000	-4,517,000	-137,771,000	-4,381,000	-3,728,000	-6,195,000	-117,580,000	-117,580,000	-4,494,000	-3,952,000	-5,448,000	-100,022,000	-3,218,000	-85,954,000	-88,211,000	-5,543,000	-5,460,000	-6,523,000	-67,065,000	-47,897,000	-3,338,000	-5,715,000	25,498,489	-3,439,828	-3,151,331	-32,625,253
capital expenditures	-201,000	-50,000	0	-57,000	-104,000	-121,000	-1,635,000	0	0	0	-37,000	0		-31,000	-351,000	-19,000	-12,000	-65,000	-159,000	-119,000	-126,000	-431,000	-718,000	-47,000	-42,000	-135,000	-286,000	-410,000	-257,000	-113,000	-45,000	-63,000	-77,000	-29,000	-82,000	-198,000	-110,000	-75,000	-90,000	-7,000	-22,000	17,000	0	0	-34,000	0	-16,000	-48,000	-110,000	-40,000	-65,000	-4,000	-18,000	-58,000	-52,000	-34,000	-7,000	-7,000	0	0	0	-61,000	-61,000	0	0	0	-61,000	0	0	0	-61,000	-61,000	-7,000	0	0	-54,000	0	0	-54,000	0	0	0	-54,000	5,000	-8,000		0	0	0	-53,966
free cash flows	-16,973,000	38,398,000	54,481,000	43,882,000	5,024,000	59,179,000	72,194,000	41,182,000	23,756,000	5,887,000	52,872,000	42,286,000		33,357,000	33,297,000	18,021,000	35,235,000	49,362,000	48,545,000	44,220,000	25,296,000	34,640,000	29,726,000	53,139,000	33,227,000	48,319,000	38,141,000	25,145,000	23,424,000	21,406,000	44,460,000	15,148,000	34,353,000	24,854,000	10,843,000	15,368,000	9,451,000	4,494,000	8,845,000	1,583,000	3,275,000	4,180,000	883,000	-139,000	-1,811,000	-1,403,000	-5,945,000	-9,032,000	-11,170,000	-7,706,000	-8,667,000	-9,240,000	-11,572,000	-8,800,000	-9,281,000	-7,926,000	-10,164,000	-10,164,000	-160,463,000	-6,604,000	146,962,000	-161,525,000	-161,525,000	-5,455,000	-6,426,000	-4,517,000	-137,832,000	-4,381,000	-3,728,000	-6,195,000	-117,641,000	-117,641,000	-4,501,000	-3,952,000	-5,448,000	-100,076,000	-3,218,000	-85,954,000	-88,265,000	-5,543,000	-5,460,000	-6,523,000	-67,119,000	-47,892,000	-3,346,000		25,498,489	-3,439,828	-3,151,331	-32,679,219
cash flows from investing activities:
purchases of property and equipment	-201,000	-50,000	0	-57,000	-104,000	-121,000	-1,635,000			0	-37,000			-31,000	-351,000	-19,000	-12,000	-65,000	-159,000	-119,000	-126,000	-431,000	-718,000	-47,000	-42,000	-135,000	-286,000	-410,000	-257,000	-113,000	-45,000	-63,000	-77,000	-29,000	-82,000	-198,000	-110,000	-75,000	-90,000	-7,000	-22,000	17,000	0	0	-34,000	0	-16,000	-48,000	-110,000	-40,000	-65,000	-4,000	-18,000	-58,000	-52,000	-34,000	-7,000	-7,000				-61,000	-61,000	0	0	0	-61,000	0	0	0	-61,000	-61,000	-7,000	0	0	-54,000	0		-54,000	0	0	0	-54,000	5,000	-8,000			0	0	-53,966
proceeds from sales and maturities of marketable securities	57,071,000		52,000,000	93,458,000	112,078,000
purchases of marketable securities	-52,328,000	-143,833,000	-37,355,000	-23,274,000	-115,145,000	-144,572,000	-223,134,000	-142,728,000	-77,876,000	-29,902,000	-210,031,000			-96,644,000	-78,851,000	-86,960,000	-92,611,000	0	-89,537,000	-95,880,000	-127,388,000	-97,020,000	-103,780,000	-170,845,000	-48,469,000	-75,704,000	-92,330,000	-60,066,000	-70,935,000	-55,799,000	-81,661,000	-44,798,000	-50,866,000	-27,419,000	-11,565,000	-14,750,000	-19,303,000
net cash from investing activities	4,542,000		14,645,000	70,127,000	-3,171,000	-64,360,000	-44,036,000	-60,194,000	-9,014,000		-109,570,000	-24,097,000	207,475,000	-17,241,000	-4,790,000	-41,800,000	-50,496,000	140,471,000	-25,803,000	24,742,000	-3,284,000	11,220,000	-64,273,000	-85,944,000	19,734,000	-61,989,000	-54,316,000																											-58,000	-52,000	-34,000	-7,000	-7,000				-61,000	-61,000	0	0	0	-61,000	0	0	1,450,000	-1,511,000	-1,511,000	2,931,000	-6,532,000	0	-54,000	-3,914,000	-2,620,000	-54,000	8,196,000	4,939,000	8,199,000	-21,937,000	-34,856,000	1,889,000	3,286,000	-9,695,616	-9,771,752	-19,992,116	-53,966
cash flows from financing activities:
proceeds from stock option exercises, net of issuance costs	3,984,000	2,861,000	2,033,000	9,235,000	1,740,000	889,000
proceeds from purchases under the employee stock purchase program	2,537,000	2,461,000	2,170,000	3,275,000	1,715,000	1,532,000	1,289,000	1,698,000	940,000
repurchases of common stock in connection with stock repurchase program		0	-42,464,000	-103,018,000	-27,433,000
cash paid to satisfy statutory withholding requirement for net settlement of cashless option exercises and vesting of restricted stock grants	-5,761,000	-36,538,000	-8,152,000	-12,426,000	-15,825,000	-6,985,000	-11,651,000	-1,909,000	-1,756,000	-995,000	-5,059,000	-1,824,000	-1,228,000	-846,000
net cash from financing activities	760,000	-31,216,000	-46,413,000	-102,934,000	-39,803,000	-4,564,000	-21,092,000	-2,150,000	-543,000	766,000	-3,916,000	-145,754,000	181,000	-61,000	-13,961,000	-2,756,000	-506,000	-206,969,000	-23,643,000	-26,032,000	-45,947,000	-661,000	5,866,000	6,804,000	205,000	-144,000	2,696,000	-15,908,000	-15,289,000	-12,031,000	-8,270,000	4,044,000	1,922,000	2,567,000	-1,841,000	-4,971,000	-3,708,000	-823,000	-2,769,000	-538,000	-2,966,000	-195,000	-1,481,000			-1,129,000	-1,249,000	-612,000	-89,000	-592,000				204,000	76,010,000	198,000	13,156,000	13,156,000	178,853,000	283,000	-178,572,000	220,726,000	220,726,000	1,057,000	17,000	21,354,000	156,380,000	17,532,000	-3,000	-2,000	138,285,000	138,285,000	-41,000	681,000	-220,000	131,867,000	0	104,096,000	103,009,000	2,957,000	-2,000	11,000	91,134,000	91,087,000	35,000		-41,969,421	0	49,385,252	41,672,556
net effect of exchange rate changes on cash, cash equivalents and restricted cash	-287,000
net decrease in cash, cash equivalents and restricted cash	-11,757,000
cash, cash equivalents and restricted cash, at beginning of period	121,745,000
cash, cash equivalents and restricted cash, at end of period	109,988,000
supplemental disclosure:
exercise cost of shares repurchased for net settlement of cashless option exercises	4,341,000				5,261,000				1,798,000		13,667,000	3,286,000	5,246,000	2,413,000
reconciliation of cash, cash equivalents and restricted cash
cash and cash equivalents	108,738,000
restricted cash included in other assets	1,250,000
adjustments to reconcile net income to net cash from operating activities:
accretion of discount on marketable securities							-2,866,000
amortization of right-of-use asset						179,000	181,000																			332,000	364,000	359,000	413,000
insurance recovery receivable related to melucci litigation						0	0	0	14,000,000
other assets		2,896,000	254,000			363,000	-34,000	-551,000	153,000					23,000	-3,247,000			1,023,000	34,000			10,000	-474,000	-1,095,000	7,000	-3,298,000	0	-75,000	-25,000		0	20,000	-23,000	12,939,000	-12,940,000	0	-25,000								-10,000	1,000	-3,000	3,000	9,000		0	0	-3,000	8,000	231,000	-188,000	-40,000	-40,000	-96,000	-8,000	100,000	-28,000	-28,000	-9,000	-9,000	-6,000	-80,000	125,000	-32,000	6,000	-180,000	-180,000	-6,000	-106,000	-1,000	-63,000	1,000	-67,000	-61,000	5,000	-3,000	-4,000	-63,000	-31,000	7,000	-4,000		-4,644	-178	-51,678
accrued and other liabilities		-13,236,000	17,158,000	5,945,000	-5,939,000	10,711,000	19,624,000	-1,207,000	9,114,000	-19,046,000	17,416,000	11,252,000	8,027,000	1,180,000	4,668,000	-7,916,000	4,995,000	3,341,000	2,805,000	3,550,000	-3,217,000	2,232,000	-3,687,000	3,048,000	-3,676,000	1,690,000	5,142,000
accrued settlement related to melucci litigation						0	0	0	-14,000,000
long-term accrued income taxes		1,044,000	-1,545,000	1,424,000	169,000	1,237,000	910,000	1,068,000	562,000	-163,000	518,000	553,000	302,000	2,274,000	1,842,000	2,465,000	2,107,000				597,000
operating lease liability		-251,000	-247,000	-230,000	-101,000	145,000	142,000	-29,000	-75,000	-74,000	-72,000	-575,000	-568,000	-564,000	-557,000	-552,000	-526,000	-520,000	-513,000	-508,000	-484,000					-344,000	-378,000	-373,000	-357,000
proceeds from maturities of marketable securities						80,333,000	180,733,000	82,950,000	68,862,000	47,000,000	100,498,000	64,820,000	207,475,000	79,434,000	74,412,000	45,179,000	42,127,000	90,073,000	63,893,000	120,741,000	124,230,000	108,671,000	40,225,000	84,948,000	68,245,000	13,850,000	38,300,000	59,320,000	70,825,000	54,155,000	48,200,000	23,650,000	16,650,000
net cash provided (used in) by investing activities
repurchase of common stock in connection with tender offer										0	0
net effect of exchange rate changes on cash and cash equivalents		-32,000	-320,000
net increase in cash and cash equivalents		-4,643,000			-37,846,000	-9,624,000	8,701,000	-21,162,000	14,199,000	23,751,000	-60,577,000	-127,565,000	233,613,000	16,086,000	14,897,000			-17,071,000	-742,000	43,049,000	-23,809,000	45,630,000	-27,963,000	-25,954,000	53,208,000	-13,679,000	-13,193,000	8,491,000	8,025,000	7,731,000	2,729,000	-1,956,000	2,059,000	2,000	-2,563,000	-4,353,000	-13,560,000	3,671,000	6,076,000	1,045,000	309,000	3,985,000	-598,000	-905,000	13,705,000					-8,298,000	-9,045,000	-9,240,000	-11,572,000	-8,596,000	66,729,000	-7,728,000	2,992,000	2,992,000	18,304,000	-6,321,000	-31,549,000	59,201,000	59,201,000	-4,398,000	-6,409,000	16,837,000	18,548,000	13,151,000	-3,731,000	-4,747,000	19,194,000	19,194,000	-1,604,000	-9,803,000	-5,668,000	31,791,000	-7,132,000	15,522,000	14,744,000	5,610,000	-523,000	1,687,000	2,132,000	8,334,000	-1,414,000	-2,429,000	-26,166,548	-13,211,580	26,241,805	8,993,337
cash and cash equivalents, at beginning of period		0	0	0	127,665,000	0	0	0	135,551,000	0	0	0	66,329,000	0	0	0	77,617,000	0	0	0	76,190,000	0	0	0	31,269,000	0	0	0	41,625,000	0	0	0	31,062,000	0	0	0	51,536,000	0	0	0	40,435,000		0	0	24,248,000		0	0	54,877,000		0	0	93,032,000		0	0	39,635,000	39,635,000		0																									0	5,930,000
cash and cash equivalents, at end of period		-4,643,000	22,393,000	12,926,000	89,819,000	-9,624,000	8,701,000	-21,162,000	149,750,000	23,751,000	-60,577,000	-127,565,000	299,942,000	16,086,000	14,897,000	-26,516,000	61,862,000	-17,071,000	-742,000	43,049,000	52,381,000	45,630,000	-27,963,000	-25,954,000	84,477,000	-13,679,000	-13,193,000	8,491,000	49,650,000	7,731,000	2,729,000	-1,956,000	33,121,000	2,000	-2,563,000	-4,353,000	37,976,000	3,671,000	6,076,000	1,045,000	40,744,000		-598,000	-905,000	37,953,000		-7,194,000	-9,644,000	43,618,000		-9,045,000	-9,240,000	81,460,000		66,729,000	-7,728,000	42,627,000	42,627,000		-6,321,000	-6,971,000	59,201,000	59,201,000		-6,409,000	16,837,000	18,548,000		-3,731,000	-4,747,000	19,194,000	19,194,000		-9,803,000	-5,668,000	31,791,000		6,616,000	14,744,000		-523,000	1,687,000	2,132,000		-1,414,000	3,501,000
income taxes paid
non-cash amortization of right-of-use asset			188,000	183,000	177,000				59,000	58,000	57,000	637,000	568,000	564,000	557,000	552,000	514,000	508,000	502,000	496,000	489,000	484,000	479,000	385,000	364,000
net decrease in cash and cash equivalents																	-15,755,000																														-7,194,000	-9,644,000	-11,259,000
(accretion) of discount and amortization of premium on marketable securities
repurchase of common stock in connection with stock repurchase program							-11,710,000	-3,478,000	-476,000
proceeds from issuance of common stock under our incentive award plan, net of issuance costs								1,539,000	749,000	1,761,000	1,143,000	1,498,000	1,409,000	785,000
(accretion) of discount on marketable securities									-2,859,000
amortization of cloud computing arrangements									52,000
depreciation and amortization of property and equipment									68,000	107,000	112,000	186,000	172,000	183,000	195,000	116,000	288,000	289,000	269,000	260,000	254,000	78,000	85,000	124,000	238,000	229,000	211,000	167,000	96,000	73,000	58,000	57,000	48,000	48,000	36,000	9,000	13,000	15,000	21,000	24,000	27,000	28,000	30,000	57,000	40,000	37,000	39,000	37,000	28,000	21,000	20,000	19,000	14,000			5,000	3,000	3,000	118,000	0	-115,000	116,000	116,000	0	1,000	2,000	113,000	2,000	3,000	2,000	103,000	103,000	2,000	3,000	4,000	91,000	3,000	79,000	78,000	4,000	3,000	4,000	64,000
other
proceeds from sales of marketable securities
amortization of interest income											-2,753,000	-1,677,000	-1,503,000	-738,000	251,000	764,000	1,106,000	1,278,000	1,334,000	1,277,000	1,194,000	899,000
prepaid expenses and other assets											-6,432,000	363,000	848,000								-2,850,000
recognition of right-of-use asset and lease liability											0			0	0	0	2,816,000					0	0			3,035,000	0	0	1,878,000
excise tax payable
repurchase of common stock																			-25,774,000	-29,170,000	-33,541,000	-9,670,000	0	0	-275,000	0	0	-17,420,000	-13,555,000	-14,753,000
proceeds from exercise of stock options, net of issuance costs																550,000	1,382,000	3,047,000	4,396,000	4,748,000	4,038,000
cash paid to satisfy statutory withholding requirement for net settlement of cashless option exercises																-3,306,000	-1,888,000		-2,265,000	-1,610,000	-16,444,000
cost of shares repurchased for net settlement of cashless option exercises																6,060,000	5,149,000		2,001,000	1,659,000	6,045,000
others																						0	0
accrued clinical expenses																		-402,000	-269,000	-453,000	-138,000	-1,828,000	4,243,000	3,351,000	1,461,000	2,356,000	-1,597,000	1,181,000	1,016,000	-1,871,000	-5,000	1,911,000	1,239,000	355,000	381,000	50,000	-6,000	-308,000	812,000	-131,000	-77,000	562,000	117,000	-866,000	1,022,000	60,000	-1,367,000	-1,737,000	92,000	1,325,000	919,000	461,000	-260,000	238,000	-35,000	-141,000	137,000	137,000	704,000	-44,000	-710,000	694,000	694,000																		-1,009,000
cash paid to satisfy statutory withholding requirement for the net settlement of cashless option exercises
cost of shares repurchased for net settlement of cashless option exercise
other receivable																														0	0	20,000	12,876,000
cash paid to satisfy statutory withholding requirement for the net settlement of cashless option exercise
adjustments to reconcile net income to net cash generated from operations:
operating lease liabilities																							-474,000	-382,000	-349,000
proceeds from issuance of common stock upon exercise of options, net of issuance costs																							5,893,000	6,867,000	480,000		2,696,000	1,512,000	2,435,000		634,000	4,044,000	1,922,000
cash paid to satisfy statutory withholding requirement for net settlement of cashless option exercise																							-27,000				0	0	-4,169,000
exercise price of shares tendered in net settlement of cashless option exercise																							128,000				0	0	931,000
accretion of interest income																								105,000	-177,000		-360,000	-419,000	-634,000
accretion of interest expense																														-701,000	-474,000	-348,000	-198,000	0	37,000	149,000	270,000	367,000	455,000	523,000	584,000	652,000	697,000	737,000	762,000	804,000	895,000	935,000	1,044,000	1,070,000	1,133,000	1,092,000	1,115,000	1,105,000
amortization of debt financing costs																																		0	3,000	6,000	5,000	5,000	5,000	6,000	5,000	2,000	9,000	5,000	6,000	6,000	9,000	6,000	8,000	8,000	8,000	8,000	11,000
excess tax benefits from stock option activity																																	54,000
payments related to debt obligation
other accrued liabilities																													-4,956,000	2,895,000	1,779,000	2,753,000	-2,383,000	1,247,000	4,026,000	2,288,000	985,000	2,079,000	1,041,000	1,306,000	1,270,000	425,000	325,000	88,000	543,000	337,000	-85,000	353,000	-30,000
cash from investing activities																													-367,000		-33,506,000	-21,211,000	-34,293,000	-27,448,000	-11,647,000	-14,948,000	-19,413,000	-75,000	-90,000	-7,000	-22,000	17,000	0	0	-34,000	0	-16,000	-48,000	-110,000	-40,000	-65,000	-4,000	-18,000
adjustments to reconcile net income to net cash provided by operations:
deferred revenue																																						0	0	0	-158,000	79,000	42,000	-18,000	22,000	-17,000	6,000	15,000	4,000	-30,000	18,000	-39,000	60,000	-5,000	-5,000
deferred taxes
proceeds from exercise of warrants, net of issuance costs
proceeds from issuance of common stock upon exercise of options and warrants, net of issuance costs																																			2,772,000	718,000	1,124,000		1,267,000	2,731,000	75,000		1,009,000	1,322,000	17,381,000
payments related to long-term obligation																																			-4,613,000	-5,689,000	-4,832,000	-4,433,000	-4,036,000	-3,269,000	-3,041,000	-2,764,000	-2,490,000	-2,088,000	-1,865,000	-1,568,000	-1,276,000	-1,017,000	-995,000
adjustments to reconcile net income to net cash generated from (used in) operations:
operating activities
net loss																																									-19,000	959,000	-601,000	-1,936,000	-4,830,000	-3,895,000	-6,007,000	-7,551,000	-13,930,000	-11,124,000	-10,906,000	-11,897,000	-12,084,000	-11,124,000	-8,294,000			-11,034,000	-186,140,000	-6,435,000			-183,305,000	-7,093,000	-7,105,000		-156,311,000	-5,170,000	-4,668,000			-135,522,000	-6,171,000	-5,565,000		-113,941,000	-4,193,000	-101,866,000	-100,973,000	-3,877,000	-6,402,000		-80,295,000	-58,719,000	-5,223,000	-5,512,000	32,626,380	-4,088,765		-40,488,355
adjustments to reconcile net loss to net cash generated from operations:
investing activities
financing activities
cash and cash equivalents at beginning of period
cash and cash equivalents at end of period																																																																																							-16,093,445	-13,211,580	26,241,805	8,993,337
adjustments to reconcile net loss to net cash from operations:
net cash provided (used) in financing activities																																													15,516,000
proceeds from issuance of common stock and warrants, net of issuance costs																																																405,000	906,000
proceeds from issuance of long-term obligation, net of issuance costs
accrued compensation and other liabilities																																																		14,000	-28,000	-106,000	375,000
proceeds from issuance of common stock and warrants, including collection of stockholder notes receivable, net of cash paid for issuance costs
proceeds from issuance of long-term obligation, net of cash paid for issuance costs
payment related to long-term obligation
principal payments of obligations under capital leases																																																														-59,000	-59,000	0	0	-4,000	-55,000	-3,000	-3,000	-2,000	-45,000	-45,000	-3,000	-4,000	-3,000	-33,000	-4,000	-19,000	-20,000	-3,000	-3,000	-3,000	-8,000
non-cash expense related to stock options
other liabilities																																																							183,000	210,000	-66,000	-66,000		126,000	-2,099,000	637,000	637,000		-98,000	139,000	424,000	-68,000	23,000	102,000	377,000	377,000	-933,000	1,098,000	-141,000	535,000	616,000	378,000	454,000	-104,000	123,000	-27,000	368,000
proceeds from issuance of common stock and warrants, including collection of notes receivable, net of issuance costs																																																							46,150,000	198,000	13,156,000	13,156,000		283,000	-136,710,000	178,864,000	178,864,000		17,000	21,358,000	114,514,000		0	0	96,409,000	96,409,000
expense related to stock options
expense related to stock options, net of recoveries																																																									2,388,000	2,388,000
expense related to stock issued for services or in conjunction with license agreement																																																														95,000	95,000		0	0	95,000		11,000	0	79,000	79,000		0	4,000	75,000			75,000		0	8,000	67,000		31,000	20,000
expense related to stock issued below fair value																																																														522,000	522,000	0	0	0	522,000	0	0	0	522,000	522,000	0	0	0	522,000	0		522,000	0	0	6,000	516,000					17,000	17,000	380,487
interest accrued on convertible promissory note																																																														104,000	104,000		0	0	104,000		0	0	104,000	104,000		0	0	104,000			104,000		0	0	104,000
settlement of liquidated damages in stock																																																														1,281,000	1,281,000	0	0	0	1,281,000	0	0	0	1,281,000	1,281,000
purchases of investments																																																														-118,320,000	-118,320,000		0
maturities of investments																																																														118,320,000	118,320,000		0
proceeds from issuance of convertible preferred stock, net of cash paid for issuance costs																																																														40,378,000	40,378,000	0	0	0	40,378,000	0	0	0	40,378,000	40,378,000	0	0	0	40,378,000	0		40,378,000	0	0	0	40,378,000					0	0	40,378,669
proceeds from issuance of convertible notes																																																														1,543,000	1,543,000	0	0	0	1,543,000	0	0	0	1,543,000	1,543,000		0	0	1,543,000			1,543,000		0	0	1,543,000
stock-based compensation, net of recoveries
expense related to stock issued for services																																																																																								0	0	45,696
expense related to stock issued in conjunction with license agreement																																																																																								0	0	14,570
interest accrued on convertible promissory notes																																																																																								0	5,208	98,561
purchases of short-term and long-term investments																																																																			-118,320,000	0	0	6,000	-118,326,000	-118,326,000	2,938,000	-6,532,000	0	-114,726,000	-4,364,000		-108,346,000	-4,000	-1,000	-11,000	-108,330,000	-85,911,000	-7,589,000	-9,499,000
maturities of short-term investments																																																																			118,320,000	0	0	1,444,000	116,876,000	116,876,000					450,000								9,486,000				0	14,809,823
supplemental disclosure of cash flow information
interest paid
supplemental disclosure of non-cash financing activities
conversion of convertible promissory notes and accrued interest
—to convertible preferred stock
—to common stock
issuance of warrant in connection with financing agreement
issuance of common stock in settlement of liquidated damages
purchase of equipment under capital leases
expense related to stock options, net of reversals																																																												954,000	-15,710,000	17,159,000	17,159,000		545,000	502,000	14,947,000		448,000	467,000	13,088,000	13,088,000		398,000	408,000	11,454,000		10,343,000	10,230,000		377,000	402,000	8,909,000
proceeds from issuance of convertible promissory notes																																																																																								0	0	1,080,000
accrued clinical expense																																																																	-272,000
accrued clinical																																																																			692,000	-246,000	-23,000	-347,000	1,325,000	1,325,000	208,000	367,000	-470,000	884,000	267,000	2,088,000	919,000				3,584,000
proceeds from issuance of common stock and warrants, including collection of note receivable, net of cash paid for issuance costs
proceeds from repayment of stockholder notes																																																																									0	0	6,000	177,000	4,000	159,000	173,000	43,000	0	0	116,000
proceeds from issuance of common stock, net of cash paid for issuance costs																																																																													0	62,035,000	60,935,000	2,917,000	1,000	14,000	49,105,000	49,100,000	0		-73,190	0
proceeds from issuance of convertible note payable																																																																																								0	0	462,929
proceeds from convertible promissory notes
issuance of note receivable pursuant to sale of common stock and warrant
sales and maturities of short-term investments																																																																										0	0	114,726,000
proceeds from issuance of common stock and warrants, net of note receivable and cash paid for issuance costs																																																																										685,000	-223,000	89,802,000
- to convertible preferred stock																																																																										0	0	1,111,000
- to common stock																																																																										0	0	534,000
issuance of note receivable for sale of common stock and warrants																																																																										0	0	6,000,000
maturities of short-term and long-term investments																																																																															108,346,000		4,940,000	8,210,000	86,447,000			12,785,000
amortization of deferred compensation, net of reversals																																																																																				7,965,000	201,000	306,000		197,322	540,132	6,662,569
proceeds from repayment of stockholder note																																																																																							25,117	0	0	37,300
depreciation																																																																																								0	0	53,966
accrued liabilities																																																																																					447,000	-301,000		-117,285	264,255	513,848
proceeds from issuance of convertible notes payable
proceeds from issuance of capital leases, net of short-term portion																																																																																					35,000
purchases of short-term investments																																																																																									-19,992,116	-14,809,823
payment to repurchase common stock																																																																																								0	0	-250
supplemental disclosure of noncash financing activities:
issuance of preferred stock for services
supplemental disclosure of cash flow information:
supplemental disclosure of non-cash financing activities:
to common stock
to convertible preferred stock
payment of issuance costs related to initial public offering																																																																																										-360,000
proceeds from issuance of common stock																																																																																										73,908

Corcept Therapeutics Incorporated(NASDAQ:CORT)

Corcept Therapeutics Incorporated
(NASDAQ:CORT)