Quarterly
Annual
| Unit: USD | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 
|---|---|---|---|---|---|---|---|---|---|---|---|---|
  assets  | ||||||||||||
  current assets:  | ||||||||||||
  cash and cash equivalents  | 98,253,000 | 76,204,000 | 66,103,000 | 122,356,000 | 70,963,000 | 114,814,000 | 157,557,000 | 94,332,000 | 142,100,000 | 181,583,000 | 400,912,000 | 96,082,000 | 
  short-term marketable securities  | 183,126,000 | 189,083,000 | 159,673,000 | 174,844,000 | 259,183,000 | 230,233,000 | ||||||
  accounts receivable  | 2,631,000 | 24,594,000 | 55,815,000 | 23,704,000 | 32,081,000 | 30,949,000 | 19,477,000 | 67,273,000 | 48,819,000 | 66,916,000 | 33,400,000 | 6,728,000 | 
  prepaid expenses and other current assets  | 12,120,000 | 16,586,000 | 18,860,000 | 22,865,000 | 21,268,000 | 17,824,000 | 19,122,000 | 11,955,000 | 31,428,000 | 18,665,000 | 19,074,000 | 17,686,000 | 
  total current assets  | 296,130,000 | 306,467,000 | 300,451,000 | 343,769,000 | 383,495,000 | 393,820,000 | 412,926,000 | 374,634,000 | 420,336,000 | 426,372,000 | 544,706,000 | 190,656,000 | 
  long-term marketable securities  | 51,996,000 | 56,324,000 | 98,428,000 | 77,667,000 | 65,794,000 | 75,446,000 | ||||||
  long-term prepaids and other assets  | 8,855,000 | 9,096,000 | 8,919,000 | 7,228,000 | 7,181,000 | 7,676,000 | ||||||
  deferred tax asset  | 4,769,000 | 4,849,000 | 4,385,000 | 4,206,000 | 3,945,000 | 3,704,000 | 3,615,000 | 1,315,000 | 1,359,000 | 1,405,000 | 1,345,000 | 3,028,000 | 
  property and equipment  | 16,314,000 | 16,685,000 | 17,650,000 | 18,333,000 | 18,470,000 | 18,972,000 | 19,847,000 | 20,904,000 | 22,375,000 | 23,514,000 | 24,713,000 | 25,717,000 | 
  operating lease right-of-use assets  | 16,260,000 | 16,723,000 | 16,666,000 | 17,355,000 | 17,279,000 | 17,067,000 | 17,696,000 | 17,857,000 | 20,796,000 | 22,300,000 | 22,937,000 | 23,564,000 | 
  intangible assets  | 2,045,000 | 3,362,000 | 4,576,000 | 6,407,000 | 7,113,000 | 7,423,000 | 7,656,000 | 8,003,000 | 7,397,000 | 8,075,000 | 8,755,000 | 9,021,000 | 
  goodwill  | 12,016,000 | 12,016,000 | 12,016,000 | 12,016,000 | 12,016,000 | 12,016,000 | 12,016,000 | 12,016,000 | 12,016,000 | 12,016,000 | 12,016,000 | 12,016,000 | 
  total assets  | 408,385,000 | 425,522,000 | 463,091,000 | 487,152,000 | 515,634,000 | 553,752,000 | 580,880,000 | 556,366,000 | 602,054,000 | 600,743,000 | 648,725,000 | 300,263,000 | 
  liabilities and stockholders’ equity  | ||||||||||||
  current liabilities:  | ||||||||||||
  accounts payable and accrued liabilities  | 31,003,000 | 38,223,000 | 59,838,000 | 51,707,000 | 44,420,000 | 47,434,000 | 45,032,000 | 67,789,000 | 69,919,000 | 59,250,000 | 87,468,000 | 52,271,000 | 
  income tax payable  | 102,000 | 127,000 | 128,000 | 2,071,000 | 1,934,000 | 1,861,000 | 1,811,000 | 831,000 | 1,158,000 | 840,000 | 840,000 | |
  current portion of operating lease liability  | 3,586,000 | 3,258,000 | 2,740,000 | 2,943,000 | 2,839,000 | 4,155,000 | 4,261,000 | 3,841,000 | 3,645,000 | 3,372,000 | 3,322,000 | 4,605,000 | 
  deferred revenue  | 3,811,000 | 23,495,000 | 14,607,000 | 27,188,000 | 5,520,000 | 3,440,000 | 32,941,000 | 32,941,000 | 30,588,000 | 2,353,000 | 2,353,000 | 32,941,000 | 
  total current liabilities  | 38,502,000 | 65,103,000 | 88,294,000 | 83,909,000 | 54,713,000 | 56,890,000 | 55,763,000 | 72,847,000 | 93,546,000 | 67,319,000 | 95,625,000 | 57,706,000 | 
  long-term portion of operating lease liability  | 15,092,000 | 15,174,000 | 15,738,000 | 17,274,000 | 17,192,000 | 20,977,000 | 22,369,000 | 22,408,000 | 23,488,000 | 23,847,000 | 24,667,000 | 25,334,000 | 
  other long-term liabilities  | 828,000 | 856,000 | 923,000 | 929,000 | 1,229,000 | 1,594,000 | 1,701,000 | 1,858,000 | 3,597,000 | 3,595,000 | 3,101,000 | 2,934,000 | 
  deferred tax liability  | 4,850,000 | 4,815,000 | 4,761,000 | 3,455,000 | 3,398,000 | 3,351,000 | 3,300,000 | 1,968,000 | 1,916,000 | 1,856,000 | 1,788,000 | 1,590,000 | 
  total liabilities  | 73,879,000 | 100,555,000 | 124,323,000 | 120,174,000 | 109,473,000 | 115,753,000 | 116,074,000 | 132,022,000 | 153,135,000 | 127,205,000 | 155,769,000 | 120,505,000 | 
  stockholders’ equity:  | ||||||||||||
  common stock  | 1,074,079,000 | 1,021,950,000 | 1,014,327,000 | 1,005,310,000 | 1,003,481,000 | 932,138,000 | 929,396,000 | 900,490,000 | ||||
  preferred shares, 0.00001 par value; 100,000,000 authorized shares of preferred stock, out of which, one share of preferred stock is a share of special voting preferred stock and outstanding as of june 30, 2025 and december 31, 2024 (note 8a).  | ||||||||||||
  exchangeable shares, no par value, 569,902 and 570,637 issued and outstanding shares at june 30, 2025 and december 31, 2024, respectively  | 8,178,000 | |||||||||||
  additional paid-in capital  | 109,243,000 | 154,216,000 | 152,249,000 | 148,296,000 | 147,343,000 | 143,144,000 | 142,274,000 | 154,114,000 | 152,257,000 | 152,677,000 | 151,614,000 | 169,262,000 | 
  accumulated other comprehensive loss  | -6,340,000 | -6,406,000 | -6,952,000 | -5,999,000 | -7,904,000 | -7,724,000 | -6,603,000 | -8,298,000 | -7,813,000 | -5,939,000 | -6,659,000 | -6,659,000 | 
  accumulated deficit  | -850,654,000 | -852,971,000 | -830,335,000 | -797,834,000 | -746,776,000 | -709,090,000 | -677,437,000 | -662,955,000 | -634,268,000 | -583,116,000 | -558,763,000 | -868,194,000 | 
  total stockholders’ equity  | 334,506,000 | 324,967,000 | 338,768,000 | 366,978,000 | 406,161,000 | 437,999,000 | 464,806,000 | 424,344,000 | 448,919,000 | 473,538,000 | 492,956,000 | |
  total liabilities and stockholders’ equity  | 408,385,000 | 425,522,000 | 463,091,000 | 487,152,000 | 515,634,000 | 553,752,000 | 580,880,000 | 556,366,000 | 602,054,000 | 600,743,000 | 648,725,000 | |
  related party transactions  | ||||||||||||
  research collaboration and licensing agreements  | ||||||||||||
  commitments and contingencies  | ||||||||||||
  preferred shares, 0.00001 par value; 100,000,000 authorized shares of preferred stock, out of which, one share of preferred stock is a share of special voting preferred stock and outstanding as of march 31, 2025 and december 31, 2024 (note 8a).  | ||||||||||||
  exchangeable shares, no par value, 569,902 and 570,637 issued and outstanding shares at march 31, 2025 and december 31, 2024, respectively  | 8,178,000 | |||||||||||
  acquired in-process research and development assets  | ||||||||||||
  deferred revenue and other consideration  | 25,588,000 | 3,699,000 | 93,000 | 17,764,000 | ||||||||
  common shares, 0.00001 par value; 900,000,000 authorized shares of common stock at december 31, 2024 and december 31, 2023 (68,964,319 and 70,115,997 shares issued and outstanding at december 31, 2024 and 2023, respectively (note 10b).  | 1,015,618,000 | |||||||||||
  preferred shares, 0.00001 par value; 100,000,000 authorized shares of preferred stock, out of which, one share of preferred stock is a share of special voting preferred stock and outstanding as of december 31, 2024 and december 31, 2023 (note 10b).  | ||||||||||||
  exchangeable shares, no par value, 570,637 issued and outstanding shares at december 31, 2024 (december 31, 2023: 651,219) (note 10b).  | 8,188,000 | |||||||||||
  subsequent event  | ||||||||||||
  acquired in-process research and development  | 171,000 | 341,000 | 17,628,000 | 17,628,000 | 17,628,000 | 17,628,000 | 17,628,000 | 17,628,000 | 17,628,000 | |||
  preferred shares, 0.00001 par value; 100,000,000 authorized shares of preferred stock, out of which, one share of preferred stock is a share of special voting preferred stock and outstanding as of september 30, 2024 and december 31, 2023 (note 8b).  | ||||||||||||
  exchangeable shares, no par value, 570,637 and 651,219 issued and outstanding shares at september 30, 2024 and december 31, 2023, respectively  | 8,188,000 | |||||||||||
  preferred shares, 0.00001 par value; 100,000,000 authorized shares of preferred stock, out of which, one share of preferred stock is a share of special voting preferred stock and outstanding as of june 30, 2024 and december 31, 2023 (note 8b).  | ||||||||||||
  exchangeable shares, no par value, 570,637 and 651,219 issued and outstanding shares at june 30, 2024 and december 31, 2023, respectively  | 8,188,000 | |||||||||||
  preferred shares, 0.00001 par value; 100,000,000 authorized shares of preferred stock, out of which, one share of preferred stock is a share of special voting preferred stock and outstanding as of march 31, 2024 and december 31, 2023 (note 8b).  | ||||||||||||
  exchangeable shares, no par value, 570,637 and 651,219 issued and outstanding shares at march 31, 2024 and december 31, 2023, respectively  | 8,188,000 | |||||||||||
  short-term investments  | 216,770,000 | 201,074,000 | 197,989,000 | 159,208,000 | 91,320,000 | 70,160,000 | ||||||
  deferred financing fees  | 108,000 | 49,000 | 73,000 | 10,000 | 1,293,000 | |||||||
  long-term investments  | 82,148,000 | 95,674,000 | 92,235,000 | 72,474,000 | 886,000 | 886,000 | ||||||
  long-term prepaid assets  | 7,240,000 | 8,286,000 | 7,912,000 | 16,886,000 | 15,729,000 | 16,454,000 | ||||||
  fair value of liability-classified stock options  | 960,000 | 1,642,000 | ||||||||||
  common shares, 0.00001 par value; 900,000,000 authorized shares of common stock at december 31, 2023 and december 31, 2022 (70,115,997 and 63,059,501 shares issued and outstanding at december 31, 2023 and 2022, respectively (note 10b).  | 997,227,000 | |||||||||||
  preferred shares, 0.00001 par value; 100,000,000 authorized shares of preferred stock, out of which, one share of preferred stock is a share of special voting preferred stock and outstanding as of december 31, 2023 and december 31, 2022 (note 10b).  | ||||||||||||
  exchangeable shares, no par value, 651,219 issued and outstanding shares at december 31, 2023 (december 31, 2022: 1,424,533) (note 10b).  | 9,345,000 | |||||||||||
  fair value of liability classified stock options  | 293,000 | 1,060,000 | 1,504,000 | 830,000 | ||||||||
  preferred shares, 0.00001 par value; 100,000,000 authorized shares of preferred stock, out of which, one share of preferred stock is a share of special voting preferred stock and outstanding as of september 30, 2023 and december 31, 2022 (note 8b).  | ||||||||||||
  exchangeable shares, no par value, 651,219 and 1,424,533 issued and outstanding shares at september 30, 2023 and december 31, 2022, respectively  | 9,345,000 | |||||||||||
  subsequent events  | ||||||||||||
  preferred shares, 0.00001 par value; 100,000,000 authorized shares of preferred stock, out of which, one share of preferred stock is a share of special voting preferred stock and outstanding as of june 30, 2023 and december 31, 2022 (note 8b).  | ||||||||||||
  exchangeable shares, no par value, 651,388 and 1,424,533 issued and outstanding shares at june 30, 2023 and december 31, 2022, respectively  | 9,347,000 | |||||||||||
  preferred shares, 0.00001 par value; 100,000,000 authorized shares of preferred stock, out of which, one share of preferred stock is a share of special voting preferred stock and outstanding as of march 31, 2023 and december 31, 2022 (note 8b).  | ||||||||||||
  exchangeable shares, no par value, 656,888 and 1,424,533 issued and outstanding shares at march 31, 2023 and december 31, 2022, respectively  | 9,426,000 | |||||||||||
  common shares, 0.00001 par value; 900,000,000 authorized shares of common stock at december 31, 2022 (no par value, unlimited shares at december 31, 2021; 63,059,501 and 46,633,935 shares issued and outstanding at december 31, 2022 and 2021, respectively (note 10b).  | 886,322,000 | |||||||||||
  preferred shares, 0.00001 par value; 100,000,000 authorized shares of preferred stock, out of which, one share of preferred stock is a share of special voting preferred stock and outstanding as of december 31, 2022 (december 31, 2021: nil) (note 10b).  | ||||||||||||
  exchangeable shares, no par value, 1,424,533 issued and outstanding shares at december 31, 2022 (december 31, 2021: nil) (note 10b).  | 20,442,000 | |||||||||||
  liabilities and shareholders’ equity  | ||||||||||||
  other current liabilities  | ||||||||||||
  shareholders’ equity:  | ||||||||||||
  common shares, no par value; unlimited authorized shares at september 30, 2022 and december 31, 2021, respectively; 61,694,387 and 46,633,935 shares issued and outstanding at september 30, 2022 and december 31, 2021, respectively  | 885,349,000 | |||||||||||
  total shareholders’ equity  | 179,758,000 | |||||||||||
  total liabilities and shareholders’ equity  | 300,263,000 | 
The information provided in this report is taken from www.sec.gov and many other data providers. While we have conducted our best efforts to ensure that the parsed data is accurate, we cannot guarantee its accuracy. Please use caution and understand that any consequences of its use are your own responsibility.
