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Y-mAbs Therapeutics, Inc
(NASDAQ:YMAB) 

YMAB stock logo

Y-mAbs Therapeutics, Inc., a commercial-stage biopharmaceutical company, focuses on the development and commercialization of novel antibody based therapeutic products for the treatment of cancer in the United States. It offers DANYELZA, a monoclonal antibody in combination with granulocyte-macrophag...

Founded: 2015
Full Time Employees: 65
Sector: Healthcare
Industry: Biotechnology
Pharmaceuticals
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At a glance:
Bull Thesis:
Bear Thesis:
Main Competitors:
Moat:
Income Statements:
Quarterly
Annual
    Unit: USD2025-06-30 2025-03-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 
                               
      ​
    		                           
      revenues
    		                           
      net product revenue
    		19,025,000 20,904,000                          
      license revenue
    		500,000    500,000  500,000   15,000,000  1,000,000    2,000,000            
      total revenues
    		19,525,000 20,904,000 18,461 22,798,000 19,931,000 23,363,000 20,454,000 20,751,000 20,251,000 31,447,000 12,537,000 10,797,000 10,486,000               
      yoy
    		-2.04% -10.53% -99.91% 9.86% -1.58% -25.71% 63.15% 92.19% 93.12%                   
      qoq
    		-6.60% 113133.30% -99.92% 14.38% -14.69% 14.22% -1.43% 2.47% -35.60% 150.83% 16.12% 2.97%                
      cost of goods sold
    		2,662,000 3,001,000 2,248 3,014,000 2,097,000 2,039,000 2,595,000 4,649,000 2,083,000 2,020,000 2,475,000 1,140,000 1,831,000 1,461,000 550,000 200,000 93,000           
      gross profit
    		16,863,000 17,903,000                          
      yoy
    		                           
      qoq
    		-5.81%                           
      gross margin %
    		86.37% 85.64% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% 
      operating costs and expenses
    		                           
      license royalties
    		50,000    50,000  50,000     100,000                
      research and development
    		11,104,000 11,359,000 11,168 12,341,000 13,267,000 13,388,000 15,358,000 12,055,000 13,418,000 19,787,000 22,453,000 26,420,000 22,912,000 28,757,000 23,131,000 19,778,000 21,579,000 24,011,000 21,005,000 30,059,000 18,622,000 16,827,000 19,660,000 14,494,000 12,511,000 11,041,000 8,731,000 
      selling, general, and administrative
    		11,313,000 13,087,000 13,613 17,232,000 11,425,000 11,135,000 10,200,000 11,270,000 12,251,000 10,793,000 13,626,000 23,082,000 13,438,000 15,138,000 13,988,000 13,475,000 11,970,000           
      total operating costs and expenses
    		22,467,000 24,446,000 27,029 32,587,000 26,839,000 26,562,000 28,203,000 27,974,000 27,752,000 32,600,000 38,554,000 50,742,000 38,181,000 45,356,000 37,669,000 33,663,000            
      income from operations
    		-5,604,000 -6,543,000 -8,568 -9,789,000 -6,908,000 -3,199,000 -7,749,000 -7,223,000 -7,501,000 -1,153,000 -26,017,000 -39,945,000 -27,695,000 -35,758,000 -28,704,000 -22,712,000 -28,259,000 -20,094,000 -32,641,000 -40,452,000 -26,747,000 -23,758,000 -24,359,000 -18,634,000 -16,253,000 -14,078,000 -11,415,000 
      yoy
    		-18.88% 104.53% -99.89% 35.53% -7.91% 177.45% -70.22% -81.92% -72.92% -96.78% -9.36% 75.88% -2.00% 77.95% -12.06% -43.85% 5.65% -15.42% 34.00% 117.09% 64.57% 68.76% 113.39%     
      qoq
    		-14.35% 76265.55% -99.91% 41.71% 115.94% -58.72% 7.28% -3.71% 550.56% -95.57% -34.87% 44.23% -22.55% 24.57% 26.38% -19.63% 40.63% -38.44% -19.31% 51.24% 12.58% -2.47% 30.72% 14.65% 15.45% 23.33%  
      operating margin %
    		-28.70% -31.30% -46.41% -42.94% -34.66% -13.69% -37.89% -34.81% -37.04% -3.67% -207.52% -369.96% -264.11% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% 
      other income
    		                         -15,500 -11,000 
      interest and other income
    		2,372,000 1,352,000 1,916 640,000 439,000               59,000 568,000       
      income before income taxes
    		-3,232,000 -5,191,000 -6,652 -9,149,000 -6,469,000 -793,000 -7,560,000 -6,123,000                    
      benefit from income taxes
    		7,000 5,000  100,000 160,000 195,000 187,000 179,000                    
      net income
    		-3,239,000 -5,196,000 -6,998 -9,249,000 -6,629,000 -988,000 -7,747,000 -6,302,000 -6,390,000 1,157,000 -27,526,000   -36,893,000 -28,858,000   -19,933,000 -32,832,000 -40,393,000 -26,179,000 -23,136,000 -23,922,000 -18,036,000 -15,934,000 -14,060,000 -11,426,000 
      yoy
    		-51.14% 425.91% -99.91% 46.76% 3.74% -185.39% -71.86%   -103.14% -4.62%   85.09% -12.10%   -13.84% 37.25% 123.96% 64.30% 64.55% 109.36%     
      qoq
    		-37.66% 74149.79% -99.92% 39.52% 570.95% -87.25% 22.93% -1.38% -652.29% -104.20%    27.84%    -39.29% -18.72% 54.30% 13.15% -3.29% 32.63% 13.19% 13.33% 23.05%  
      net income margin %
    		-16.59% -24.86% -37.91% -40.57% -33.26% -4.23% -37.88% -30.37% -31.55% 3.68% -219.56% 0% 0% -Infinity% -Infinity% NaN% NaN% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% 
      other comprehensive income/
    		                           
      foreign currency translation
    		-2,013,000 -863,000 -1,083 199,000 399,000 129,500 806,000 18,000 -306,000 832,750 1,598,000 1,422,000 311,000 187,750 238,000 78,000 435,000 -19,500 -12,000 -91,000 25,000 31,000 134,000 -66,000 56,000 30,250 39,000 
      comprehensive loss
    		-5,252,000 -6,059,000 -8,081 -9,050,000 -6,230,000 -4,980,250 -6,941,000 -6,284,000 -6,696,000 -23,348,500 -25,928,000   -4,407,750 -28,620,000   -24,870,500 -32,844,000 -40,484,000 -26,154,000 -14,442,000 -23,788,000 -18,102,000 -15,878,000 -7,273,250 -11,387,000 
      net income per share
    		-0.07 -0.12 -0.16 -0.21 -0.15 -0.118 -0.18 -0.14 -0.15 -0.553 -0.63   -0.108 -0.66   -0.48 -0.82 -1.01 -0.66 -0.61 -0.7 -0.53 -0.47 -0.42 -0.42 
      weighted-average common shares outstanding, basic and diluted
    		45,318,028 45,104,476 44,626,943 44,022,356 43,779,456  43,620,532 43,663,112 43,671,589  43,718,351    43,598,350    40,187,173 39,972,174 39,753,583  34,371,927 34,193,666 34,193,666  27,330,579 
      product revenue
    		  18,461 22,798,000 19,431,000 23,363,000 19,954,000 20,751,000 20,251,000 16,447,000 12,537,000 9,797,000 10,486,000 9,598,000 8,965,000 8,951,000 5,383,000           
      provision for income taxes
    		  346                         
      other comprehensive income
    		                           
      balance december 31, 2022
    		  43,670,109                         
      stock-based compensation expense
    		  7,658                         
      balance march 31, 2023
    		  43,677,767                         
      retirement of treasury shares
    		  -58,763                         
      balance june 30, 2023
    		  43,620,192                         
      balance september 30, 2023
    		  43,621,618                         
      balance december 31, 2023
    		  43,672,112                         
      exercise of stock options
    		  71,550                         
      balance march 31, 2024
    		  43,852,638                         
      balance june 30, 2024
    		  44,567,334                         
      balance september 30, 2024
    		  44,766,802                         
      other income/(loss)
    		                           
      interest and other income/
    		     2,406,000 189,000 1,100,000              338,500 437,000 598,000 319,000   
      other income / (loss)
    		                           
      interest and other income /
    		        1,111,000     -1,135,000 -154,000 -225,000 -338,000           
      other comprehensive income /
    		                           
      gain from sale of priority review voucher
    		                62,010,000           
      interest and other loss
    		         2,310,000 -1,509,000 -1,186,000 -373,000               
      net income /
    		           -41,131,000 -28,068,000   -22,937,000 33,413,000           
      comprehensive income /
    		           -39,709,000 -27,757,000   -22,859,000 33,848,000           
      net income / (loss) per share attributable to common stockholders, basic
    		           -0.94 -0.64               
      weighted-average common shares outstanding, basic
    		           43,718,748 43,709,238   43,569,482 41,870,759           
      net income / (loss) per share attributable to common stockholders, diluted
    		           -0.94 -0.64               
      weighted-average common shares outstanding, diluted
    		           43,718,748 43,709,238   43,569,482 44,383,791           
      revenue
    		                           
      total revenue
    		             6,324,750 8,965,000 10,951,000            
      licensing royalties
    		                           
      royalties
    		               210,000            
      net income/(loss) per share attributable to common stockholders, basic
    		               -0.53 0.8           
      net income/(loss) per share attributable to common stockholders, diluted
    		               -0.53 0.75           
      total operating cost and expenses
    		                33,642,000           
      operating expenses
    		                           
      general and administrative
    		                 14,630,000 11,636,000 10,393,000 8,125,000 6,931,000 4,699,000 4,140,000 3,742,000 3,037,000 2,684,000 
      total operating expenses
    		                 40,844,000 32,641,000 40,452,000 26,747,000 23,758,000 24,359,000 18,634,000 16,253,000 14,078,000 11,415,000 
      interest and other income / (expenses)
    		                 109,250 -191,000         
      other income/
    		                           
    Balance Sheets:
    Quarterly
    Annual
      Unit: USD2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 
                                  
        assets
      		                            
        current assets
      		                            
        cash and cash equivalents
      		62,293,000 60,310,000 67,234,000 68,122,000 77,806,000 75,749,000 78,637,000 86,571,000 87,909,000 92,629,000 105,762,000 114,526,000 133,665,000 156,724,000 181,564,000 215,730,000 233,587,000 252,271,000 114,634,000 131,267,000 158,059,000 185,774,000 207,136,000 98,192,000 120,163,000 134,245,000 147,840,000 163,292,000 
        accounts receivable
      		15,740,000 17,740,000 19,688,000 19,916,000 22,191,000 20,588,000 22,454,000 18,874,000 19,118,000 18,702,000 12,531,000 9,251,000 7,208,000 9,324,000 7,712,000 7,264,000 8,517,000 5,997,000           
        inventories
      		9,719,000 7,995,000 7,214,000 9,557,000 8,498,000 8,448,000 5,065,000 7,113,000 5,187,000 8,945,000 6,702,000 6,242,000 6,794,000 5,588,000 5,512,000 4,787,000 3,820,000 1,005,000           
        other current assets
      		4,035,000 4,403,000 4,373,000 1,462,000 2,243,000 3,482,000 4,955,000 2,302,000 3,570,000 3,730,000 5,452,000 3,225,000 6,253,000 6,103,000 7,473,000 2,799,000 3,445,000 4,736,000  1,942,000 5,261,000 4,062,000  1,399,000 3,027,000 2,759,000  2,721,000 
        total current assets
      		91,787,000 90,448,000 98,509,000 99,057,000 126,763,000 108,267,000 111,111,000 114,860,000 115,784,000 124,006,000 130,447,000 133,244,000 153,920,000 177,739,000 202,261,000 230,580,000 249,369,000 264,009,000  133,209,000 163,320,000 189,836,000  99,591,000 123,190,000 137,034,000  166,044,000 
        property and equipment
      		269,000 161,000 42,000 53,000 87,000 153,000 224,000 296,000 375,000 511,000 604,000 1,372,000 1,554,000 1,697,000 1,847,000 1,846,000 1,919,000 2,095,000  1,888,000 1,894,000 1,992,000  1,689,000 390,000 400,000  162,000 
        operating lease right-of-use assets
      		3,109,000 601,000 817,000 1,075,000 1,271,000 1,179,000 1,412,000 1,593,000 1,178,000 1,369,000 1,739,000 2,169,000 2,381,000 3,155,000 3,842,000 2,802,000 3,398,000 3,979,000  5,123,000 1,758,000 1,865,000  2,086,000 2,216,000 2,320,000   
        intangible assets
      		2,177,000 2,213,000 2,276,000 2,366,000 2,454,000 2,543,000 2,631,000 2,720,000 2,809,000 2,898,000 2,986,000 1,530,000 1,574,000 1,618,000 1,663,000              
        inventories, long-term
      		19,223,000 18,472,000 17,772,000                          
        other assets
      		646,000 718,000 488,000 18,366,000 13,460,000 11,173,000 12,491,000 9,415,000 12,250,000 8,661,000 5,680,000 5,600,000 5,749,000 6,838,000 3,170,000 4,751,000 4,793,000 4,833,000  2,975,000 357,000 381,000  318,000 244,000 243,000  188,000 
        total assets
      		117,211,000 112,613,000 119,904,000 120,917,000 144,035,000 123,315,000 127,869,000 128,884,000 132,396,000 137,445,000 141,456,000 143,915,000 165,178,000 191,047,000 212,783,000 239,979,000 259,479,000 274,916,000 132,047,000 143,195,000 167,329,000 194,074,000 216,366,000 103,684,000 126,040,000 139,997,000 151,924,000 166,394,000 
        liabilities and stockholders’ equity
      		                            
        liabilities
      		                            
        accounts payable
      		7,571,000 4,627,000 6,662,000 7,878,000 10,190,000 6,728,000 6,060,000 7,610,000 7,252,000 8,843,000 14,175,000 13,723,000 11,291,000 14,661,000 13,552,000 11,024,000 6,803,000 6,543,000  10,320,000 9,825,000 10,260,000  7,628,000 8,911,000 5,907,000  6,827,000 
        accrued liabilities
      		14,888,000 13,875,000 16,406,000 16,638,000 12,788,000 9,989,000 13,166,000 13,304,000 16,152,000 16,222,000 13,241,000 17,092,000 17,067,000 12,930,000 12,540,000 12,486,000 12,169,000 8,486,000  7,570,000 5,313,000 4,035,000  5,848,000 4,215,000 3,877,000  2,489,000 
        operating lease liabilities, current portion
      		486,000 455,000 630,000 776,000 842,000 888,000 902,000 898,000 829,000 855,000 868,000 1,200,000 1,092,000 1,451,000 1,783,000 1,849,000 2,014,000 1,971,000  1,887,000 569,000 548,000  516,000 502,000 517,000   
        total current liabilities
      		22,945,000 18,957,000 23,698,000 25,292,000 43,470,000 17,605,000 20,128,000 21,812,000 24,233,000 25,920,000 28,284,000 32,015,000 29,450,000 29,042,000 27,875,000 25,359,000 20,986,000 17,000,000  19,777,000 15,707,000 14,843,000  13,992,000 13,628,000 10,301,000  9,316,000 
        accrued milestones
      		3,200,000 3,200,000 3,200,000 2,000,000       2,250,000 2,250,000                 
        operating lease liabilities, long-term portion
      		2,638,000 148,000 190,000 299,000 432,000 293,000 517,000 725,000 416,000 629,000 899,000 1,019,000 1,302,000 1,598,000 1,851,000 654,000 988,000 1,515,000  2,517,000 1,399,000 1,543,000  1,821,000 1,980,000 2,133,000   
        other liabilities
      		935,000 851,000 812,000 897,000 847,000 853,000 864,000 822,000 816,000 817,000 802,000 733,000 780,000 835,000 851,000 871,000 939,000 1,934,000  1,923,000 1,729,000 457,000       
        total liabilities
      		29,718,000 23,156,000 27,900,000 28,488,000 48,699,000 24,126,000 26,884,000 28,734,000 27,715,000 29,616,000 32,235,000 36,017,000 33,782,000 33,575,000 32,677,000 29,134,000 25,163,000 22,699,000 26,211,000 26,683,000 21,321,000 18,744,000 17,463,000 17,745,000 17,658,000 14,484,000 11,397,000 11,366,000 
        commitments and contingencies
      		                            
        stockholders’ equity
      		                            
        preferred stock, 0.0001 par value...
      		                            
        common stock, 0.0001 par value...
      		5,000 5,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000  4,000 4,000 4,000  3,000 3,000 3,000  3,000 
        additional paid-in capital
      		583,671,000 580,383,000 576,872,000 572,807,000 567,633,000 562,436,000 558,002,000 554,779,000 552,369,000                    
        accumulated other comprehensive income
      		-612,000 1,401,000 2,264,000 -36,000 1,047,000 848,000 449,000 1,849,000 1,043,000 1,025,000 1,331,000 4,702,000 3,104,000 1,682,000 1,371,000 225,000    -28,000 -16,000 75,000  131,000  63,000  -48,000 
        accumulated deficit
      		-495,571,000 -492,332,000 -487,136,000 -480,346,000 -473,348,000 -464,099,000 -457,470,000 -456,482,000 -448,735,000 -442,433,000 -436,043,000 -437,200,000 -409,674,000 -368,543,000 -340,475,000 -303,582,000 -274,724,000 -251,787,000 -285,200,000 -265,267,000 -232,435,000 -192,042,000 -165,863,000 -142,727,000 -118,805,000 -100,769,000 -84,835,000 -70,775,000 
        total stockholders’ equity
      		87,493,000 89,457,000 92,004,000 92,429,000 95,336,000 99,189,000 100,985,000 100,150,000 104,681,000 107,829,000 109,221,000 107,898,000 131,396,000 157,472,000 180,106,000 210,845,000 234,316,000 252,217,000 105,836,000 116,512,000 146,008,000 175,330,000 198,903,000 85,939,000 108,382,000 125,513,000 140,527,000 155,028,000 
        total liabilities and stockholders’ equity
      		117,211,000 112,613,000 119,904,000 120,917,000 144,035,000 123,315,000 127,869,000 128,884,000 132,396,000 137,445,000 141,456,000 143,915,000 165,178,000 191,047,000 212,783,000 239,979,000 259,479,000 274,916,000  143,195,000 167,329,000 194,074,000  103,684,000 126,040,000 139,997,000  166,394,000 
        insurance recovery receivable related to legal settlement
      		    16,025,000                        
        accrued legal settlement
      		    19,650,000                        
        accrued milestone and royalty payments
      		    3,950,000 5,375,000 5,375,000  2,250,000 2,250,000   2,250,000 2,100,000 2,100,000 2,250,000 2,250,000 2,250,000  2,466,000 2,486,000 1,901,000  1,932,000 2,050,000 2,050,000  2,050,000 
        ​
      		                            
        accrued milestone payments
      		       5,375,000                     
        additional paid in capital
      		         549,233,000 543,929,000 540,392,000 537,962,000 524,329,000 519,206,000 514,198,000 509,049,000 504,091,000  381,803,000 378,455,000 367,293,000  228,532,000 227,187,000 226,216,000  225,848,000 
        accumulated other comprehensive loss
      		                -13,000 -91,000           
        consolidated balance sheet data:
      		                            
        working capital
      		                  102,828,000    198,369,000    142,409,000  
        restricted cash
      		                         30,000  31,000 
        deferred offering costs
      		                            
      Cashflow Statements:
      Quarterly
      Annual
        Unit: USD2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 
                                   
          cash flows from operating activities
        		                           
          net loss
        		-3,240,000 -5,196,000 -6,790,000 -6,998,000 -9,249,000 -6,629,000 -988,000 -7,747,000 -6,302,000 -6,390,000 1,157,000 -27,526,000 -41,131,000 -28,068,000 -36,893,000    -19,933,000 -32,832,000 -40,393,000 -26,179,000 -23,136,000 -23,922,000 -18,036,000 -15,934,000 -14,060,000 
          adjustments to reconcile net loss to net cash from operating activities:
        		                           
          depreciation and amortization
        		53,000 71,000 102,000 121,000 153,000 159,000 161,000 168,000 224,000 182,000 230,000 226,000 188,000 195,000 291,000 145,000 216,000 130,000 117,000 93,000 100,000 86,000 79,000 48,000 20,000 19,000 14,000 
          stock-based compensation
        		2,902,000 3,341,000 3,079,000 4,195,000 3,439,000 3,846,000 3,123,000 2,410,000 3,616,000 5,304,000 3,537,000 3,341,000 13,633,000 5,091,000 4,908,000 4,901,000 4,827,000 4,698,000 8,336,000 3,134,000 2,454,000 2,211,000 1,477,000 1,345,000 971,000 864,000 495,000 
          foreign currency transactions
        		-1,940,000 -812,000           1,422,000 311,000 1,146,000 238,000 78,000 435,000 -514,000 4,000 -91,000 25,000 -80,000 134,000 -62,000 51,000 -4,000 
          changes in assets and liabilities:
        		                           
          accounts receivable
        		2,000,000 1,948,000 -292,000 2,275,000 -1,603,000 1,866,000 -3,580,000 244,000 -416,000 -6,171,000 -3,280,000 -2,043,000 2,116,000 -1,612,000 -448,000 1,253,000 -2,520,000 -5,997,000          
          inventories
        		-1,670,000 -724,000 2,343,000 -1,059,000 -50,000 -3,383,000 2,048,000 -1,926,000 3,758,000 -2,243,000 -460,000 552,000 -1,206,000 -76,000 -725,000 -967,000 -2,815,000 -1,005,000          
          insurance recovery receivable related to legal settlement
        		                           
          other current assets
        		368,000 -30,000 -2,911,000 781,000 1,239,000 1,473,000 -2,654,000 1,269,000 -320,000 1,722,000 -3,279,000 1,699,000 -150,000 1,370,000 -4,674,000 646,000 1,291,000 2,993,000 -5,787,000 2,381,000 -1,201,000 759,000 -3,420,000 1,627,000 -267,000 902,000 -940,000 
          inventories, long-term
        		-751,000 -700,000                          
          other assets
        		72,000 -230,000 5,930,000 -4,906,000 -2,287,000 1,318,000 -3,077,000 2,835,000 -3,587,000 -2,983,000 -80,000 149,000 1,089,000 -3,668,000 1,581,000 42,000 40,000 -1,543,000 -313,000 -11,000 24,000 -11,000 -51,000 -74,000 -1,000 -56,000 1,000 
          accounts payable
        		4,877,000 -1,223,000 -3,659,000 -1,132,000 3,230,000 176,000 -660,000 -47,000 -1,378,000 -4,771,000 -1,090,000 2,432,000 -3,370,000 1,109,000 2,528,000 4,221,000 260,000 -2,829,000 -948,000 495,000 -435,000 1,740,000 1,586,000 -1,984,000 3,149,000 -134,000 -439,000 
          accrued liabilities and other
        		-1,020,000 -3,356,000 3,189,000 863,000 1,569,000 -2,795,000 -1,519,000 1,051,000 -11,000 2,682,000 -5,275,000 -30,000 4,309,000 423,000 -1,577,000 303,000 2,804,000 -146,000 1,347,000 2,591,000 3,200,000 -387,000 -1,034,000 1,431,000 186,000 805,000 1,356,000 
          accrued legal settlement
        		                           
          net cash from operating activities
        		1,651,000 -6,911,000 -1,870,000 -10,665,000 298,000 -3,477,000 -8,036,000 -1,338,000 -4,734,000 -13,124,000 -8,661,000 -19,235,000 -23,100,000 -24,925,000 -33,863,000 -18,076,000 -18,756,000 -31,861,000 -17,695,000 -24,145,000 -27,635,000 -21,756,000 -24,579,000 -21,395,000 -14,040,000 -13,483,000 -13,577,000 
          capital expenditures
        		0 -127,000 0 0 0 0 0 0 0 0 0 0 0  -155,000 -71,000 -41,000 -400,000 -44,000 -103,000 -2,000 -26,000 -1,147,000 -617,000 -75,000 -126,000 -57,000 
          free cash flows
        		1,651,000 -7,038,000 -1,870,000 -10,665,000 298,000 -3,477,000 -8,036,000 -1,338,000 -4,734,000 -13,124,000 -8,661,000 -19,235,000 -23,100,000  -34,018,000 -18,147,000 -18,797,000 -32,261,000 -17,739,000 -24,248,000 -27,637,000 -21,782,000 -25,726,000 -22,012,000 -14,115,000 -13,609,000 -13,634,000 
          net cash from investing activities
        		0 -127,000             -455,000 -71,000 -41,000 61,610,000 -44,000 -2,713,000 -2,000 -26,000 -1,147,000 -617,000 -75,000 -126,000 -57,000 
          purchase of property and equipment
        		0 -127,000             -155,000 -71,000 -41,000 -400,000 -44,000 -103,000 -2,000 -26,000 -1,147,000 -617,000 -75,000 -126,000 -57,000 
          cash flows from financing activities
        		                           
          proceeds from exercised stock options
        		332,000 114,000 986,000 979,000 1,758,000 588,000     0 52,000 0 32,000 100,000 248,000 131,000 110,000 1,419,000 215,000 0 370,000      
          net cash from financing activities
        		332,000 114,000 986,000 979,000 1,758,000 588,000     0 52,000 0 32,000 100,000 248,000 131,000 107,835,000 1,419,000 215,000 0 370,000     -1,842,000 
          effect of exchange rates on cash and cash equivalents
        		   2,000 1,000 1,000 2,000 0 14,000 -9,000 -103,000 44,000 41,000 53,000 52,000 42,000 -18,000 53,000 -313,000        24,000 
          net decrease in cash and cash equivalents
        		1,983,000 -6,924,000 -888,000 -9,684,000 2,057,000 -2,888,000 -7,934,000 -1,338,000 -4,720,000 -13,133,000         -16,633,000         
          cash and cash equivalents at the beginning of period
        		0 67,234,000 0 0 0 78,637,000 0 0 0 105,762,000 0 0 0 181,564,000 0 0 0 114,634,000 0         
          cash and cash equivalents at the end of period
        		1,983,000 60,310,000 -888,000 -9,684,000 2,057,000 75,749,000 -7,934,000 -1,338,000 -4,720,000 92,629,000 -8,764,000 -19,139,000 -23,059,000 156,724,000 -34,166,000 -17,857,000 -18,684,000 252,271,000 -16,633,000         
          ​
        		                           
          supplemental disclosure of non-cash activities
        		                           
          right-of-use assets obtained in exchange for lease obligations
        		  0 0   0    0        0    0 69,000 -1,488,000 2,320,000  
          property and equipment purchase in accrued liabilities and other
        		                           
          foreign currency and other transactions
        		  2,443,000 -1,180,000 232,000 492,000    -456,000 -121,000                 
          provision for bad debt
        		                           
          cash flows from investing activities
        		                           
          supplemental disclosure of cash flow information
        		                           
          cash paid for income taxes
        		                           
          acquisition of treasury shares upon repayment of secured promissory note
        		                           
          foreign currency transactions and other transactions
        		      -890,000                     
          intangible assets acquisition in accrued liabilities
        		                           
          acquisition of treasury shares upon repayment of secured promissory note – refer to note 10
        		      0 0   0                 
          intangible assets acquisition in accrued milestones and royalty payments
        		            0 1,500,000              
          gain from sale of priority review voucher
        		              0 0 0 -62,010,000          
          acquisition of intangible assets
        		                           
          net proceeds from sale of priority review voucher
        		              0 0 0 62,010,000          
          proceeds from issuance of common stock, net of issuance costs
        		              0 0 0 107,725,000         -1,842,000 
          net increase in cash and cash equivalents
        		          -8,764,000 -19,139,000 -23,059,000 -24,840,000 -34,166,000 -17,857,000 -18,684,000 137,637,000         -15,452,000 
          intangible assets acquisition in accrued milestones
        		                           
          property and equipment purchases in accounts payable
        		                 60,000     -703,000 729,000 -65,000 88,000  
          non-cash expense in connection with equity issuance to msk/mit
        		                  0 0        
          non-cash expense in connection with equity issuance to inventors
        		                  0 0        
          loans to inventors
        		                  0         
          net income
        		                -22,937,000 33,413,000          
          effect of exchange rates on cash, cash equivalents and restricted cash
        		                    -78,000 50,000 -34,000 41,000 3,000 13,000  
          net decrease in cash, cash equivalents and restricted cash
        		                    -27,715,000 -21,362,000      
          cash, cash equivalents and restricted cash at the beginning of period
        		                    0 207,136,000 0 0 0 147,871,000 0 
          cash, cash equivalents and restricted cash at the end of period
        		                    -27,715,000 185,774,000 108,944,000 -21,971,000 -14,112,000 134,275,000 -15,452,000 
          payment of offering costs for private placement
        		                           
          net increase in cash, cash equivalents and restricted cash
        		                      108,944,000 -21,971,000 -14,112,000 -13,596,000  
          common stock issuance costs in accounts payable
        		                           
          deferred offering costs included in other assets and accounts payable and accrued liabilities and other
        		                           
          payment of offering costs
        		                           
          supplemental disclosure of noncash financing activities
        		                           
          common stock issuance cost in accounts payable