7Baggers
Quarterly
Annual
    Unit: USD2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-09-30 2015-06-30 2015-03-31 2014-06-30 2014-03-31 2013-09-30 
      
    		                                             
      assets
    		                                             
      current assets:
    		                                             
      cash and cash equivalents
    		315,573,000 219,499,000 186,120,000 239,087,000 274,079,000 235,915,000 209,188,000 216,454,000 202,463,000 191,142,000 177,890,000 154,247,000 170,112,000 153,447,000 163,615,000 173,197,000 164,029,000 327,545,000 324,062,000 349,364,000 345,080,000 147,450,000 153,132,000 159,317,000 195,662,000 192,647,000 67,841,000 77,995,000 77,846,000 23,758,000 27,152,000 33,891,000 41,195,000 46,463,000 51,506,000 59,219,000 31,699,000 38,993,000 47,456,000 46,116,000 51,045,000 25,798,000 57,998,000 64,237,000 15,426,000 
      short-term investments
    		50,855,000 101,220,000 101,235,000 50,354,000        24,605,000  10,551,000                                
      accounts receivable
    		47,826,000 50,814,000 53,781,000 46,525,000 48,807,000 50,304,000 46,665,000 40,378,000 39,297,000 42,365,000 45,489,000 44,021,000 40,068,000 40,448,000 42,481,000 41,461,000 40,309,000 31,864,000 27,877,000 18,461,000 17,629,000 15,306,000 19,091,000 19,329,000 23,613,000 19,626,000 16,615,000 13,168,000 12,262,000 13,006,000 13,198,000 12,716,000 11,635,000 11,027,000 9,125,000 8,756,000 6,312,000 3,387,000 3,230,000 3,520,000 3,586,000 2,564,000 1,430,000 1,191,000 714,000 
      supplies and inventory
    		20,327,000 25,020,000 24,254,000 21,750,000 20,364,000 19,258,000 18,328,000 16,128,000 15,887,000 11,572,000 13,306,000 14,294,000 13,798,000 14,600,000 12,372,000                               
      prepaid expenses and other current assets
    		14,643,000 18,128,000 17,762,000 14,551,000 13,604,000 15,629,000 16,237,000 12,661,000 13,516,000 14,401,000 14,818,000 11,469,000 14,538,000 15,999,000 20,015,000 17,219,000 15,146,000 5,263,000 3,845,000 3,197,000 3,150,000 2,891,000 3,045,000 2,235,000 2,196,000 2,573,000 2,392,000 2,387,000 1,803,000 1,822,000 2,142,000 1,997,000 1,617,000 1,933,000 2,101,000 2,057,000 1,405,000 1,395,000 1,618,000 3,371,000 1,735,000 1,179,000 1,450,000 1,014,000 2,938,000 
      total current assets
    		449,224,000 414,681,000 383,152,000 372,267,000 356,854,000 321,106,000 290,418,000 285,621,000 271,163,000 259,480,000 251,503,000 248,636,000 238,516,000 235,045,000 238,483,000 243,102,000 229,308,000 371,346,000 362,092,000 375,679,000 370,315,000 172,688,000 181,362,000 187,687,000 228,079,000 219,950,000 90,616,000 96,952,000 95,374,000 41,635,000 47,049,000 53,928,000 58,207,000 62,860,000 66,295,000 73,627,000 42,952,000 47,397,000 56,194,000 57,331,000 60,714,000 33,691,000 64,178,000 69,163,000 20,470,000 
      property, plant and equipment
    		18,900,000 18,552,000 22,529,000 22,953,000 21,194,000 22,291,000 21,566,000 20,584,000 19,288,000 18,510,000 18,072,000                                   
      right-of-use assets, operating leases
    		37,301,000 38,679,000 47,624,000 48,189,000 17,031,000 18,116,000 11,167,000 10,277,000 11,297,000 12,455,000 11,308,000  13,885,000 14,816,000 15,663,000                               
      intangible assets
    		92,477,000 95,806,000 99,094,000 102,301,000 108,873,000 112,532,000 116,348,000 88,593,000 123,567,000 164,744,000 170,226,000 174,866,000 176,542,000 184,367,000 196,228,000 202,731,000 209,521,000 155,700,000 159,423,000                           
      goodwill
    		767,154,000 773,255,000 754,272,000 745,800,000 762,117,000 752,107,000 753,853,000 702,984,000 693,176,000 698,920,000 699,718,000 695,891,000 676,885,000 690,040,000 704,368,000 707,904,000 714,273,000 471,764,000 474,838,000 2,725,000 2,725,000 2,725,000 2,725,000 2,725,000 1,057,000 1,057,000 1,057,000 1,057,000 1,057,000 1,057,000 1,057,000 1,057,000 1,057,000 1,057,000 1,057,000 1,057,000 1,057,000 1,057,000 1,057,000 1,057,000 1,057,000 1,057,000    
      restricted cash
    		1,637,000 1,654,000 1,645,000 1,544,000 1,080,000 1,088,000 1,082,000 876,000 870,000 889,000 749,000 749,000 749,000 749,000 749,000 749,000 749,000 749,000 749,000 603,000 603,000 603,000 603,000 603,000 603,000 603,000 603,000 603,000 603,000 603,000 603,000   120,000 120,000 120,000 120,000 120,000 238,000 118,000 118,000 118,000 118,000 118,000  
      other assets
    		1,094,000 1,477,000 7,095,000 6,981,000 7,872,000 7,087,000 5,639,000 5,971,000 5,582,000 6,116,000 5,543,000 5,418,000 2,143,000 1,993,000 1,799,000 2,198,000 1,636,000 1,504,000 2,286,000 1,399,000 2,303,000 1,271,000 1,302,000 1,437,000 1,228,000 1,061,000 1,049,000 1,086,000 837,000 598,000 466,000 326,000 178,000 134,000 127,000 134,000 203,000 172,000 208,000 195,000 185,000 180,000 142,000 145,000 157,000 
      total assets
    		1,367,787,000 1,344,104,000 1,315,411,000 1,300,035,000 1,275,021,000 1,234,327,000 1,200,073,000 1,114,906,000 1,124,943,000 1,161,114,000 1,157,119,000 1,156,422,000 1,125,957,000 1,144,198,000 1,173,589,000 1,187,825,000 1,186,356,000 1,027,435,000 1,025,136,000 457,163,000 454,151,000 256,737,000 267,100,000 275,212,000 260,307,000 252,377,000 123,537,000 120,638,000 119,077,000 65,461,000 71,190,000 78,669,000 83,659,000 88,347,000 92,606,000 101,034,000 69,650,000 74,832,000 84,267,000 80,853,000 82,503,000 55,060,000 67,750,000 72,454,000 23,571,000 
      liabilities and stockholders’ equity
    		                                             
      current liabilities:
    		                                             
      accounts payable
    		5,509,000 11,447,000 15,709,000 8,634,000 9,670,000 12,084,000 12,152,000 12,943,000 12,531,000 12,895,000 15,655,000 11,911,000 11,114,000 10,328,000 11,273,000 12,360,000 11,201,000 8,472,000 7,137,000 3,116,000 1,932,000 2,224,000 7,665,000 2,328,000 5,568,000 4,061,000 4,064,000 2,516,000 1,175,000 1,962,000 3,356,000 3,853,000 3,161,000 2,349,000 2,611,000 2,424,000 3,081,000 2,705,000 4,340,000 6,644,000 2,688,000 6,854,000 8,539,000 7,214,000 5,604,000 
      accrued liabilities
    		48,373,000 43,707,000 35,928,000 43,826,000 43,872,000 43,455,000 30,293,000 38,427,000 34,828,000 34,427,000 30,641,000 37,774,000 32,137,000 33,565,000 38,543,000 39,475,000 29,044,000 20,756,000 16,254,000 11,705,000 10,445,000 9,386,000 10,079,000 13,734,000 9,760,000 9,820,000 8,788,000 9,186,000 9,261,000 8,429,000 8,483,000 8,175,000 8,058,000 8,450,000 6,800,000 9,110,000 7,189,000 8,910,000 7,021,000 7,365,000 7,217,000 5,396,000 5,128,000 5,267,000 4,416,000 
      current portion of deferred revenue
    		417,000 1,450,000 1,712,000 1,673,000 2,033,000 2,195,000 2,602,000 2,008,000 2,214,000 2,378,000 2,194,000 2,613,000 3,863,000 4,193,000 4,878,000 4,646,000 3,440,000 566,000 454,000 371,000                          
      current portion of acquisition-related contingent consideration
    		13,571,000 13,415,000 14,360,000 16,981,000 7,391,000 7,348,000 6,934,000 2,657,000 2,574,000 3,359,000 3,300,000 6,060,000 5,913,000 5,998,000 2,703,000 2,682,000 2,646,000 3,375,000                            
      current portion of operating lease liabilities
    		4,282,000 6,414,000 7,409,000 7,500,000 7,294,000 7,185,000 5,982,000 5,105,000 5,007,000 4,973,000 4,076,000 4,070,000 3,958,000 3,930,000 3,849,000 3,630,000                              
      current portion of other liabilities
    		  7,000 19,000 53,000 72,000 89,000 101,000 106,000 119,000 127,000 186,000 180,000 198,000 218,000 231,000 241,000                             
      total current liabilities
    		72,152,000 76,433,000 75,125,000 78,633,000 70,313,000 72,339,000 58,052,000 61,241,000 57,260,000 58,151,000 55,993,000 62,614,000 58,352,000 59,345,000 62,543,000 64,151,000 50,037,000 36,105,000 32,709,000 16,781,000 13,919,000 13,105,000 19,194,000 17,469,000 16,772,000 15,321,000 14,329,000 13,059,000 10,436,000 10,391,000 11,839,000 12,028,000 11,219,000 10,799,000 9,411,000 11,534,000 10,270,000 11,842,000 11,879,000 15,432,000 11,802,000 14,147,000 17,107,000 15,448,000 12,520,000 
      deferred tax liabilities
    		1,214,000 1,301,000 1,242,000  1,470,000 1,483,000 1,340,000  3,644,000 4,707,000 4,594,000  4,342,000 4,605,000 4,983,000                               
      acquisition-related contingent consideration, net of current portion
    		583,000 573,000 570,000 561,000 14,225,000 13,889,000 13,446,000 518,000 484,000 4,855,000 4,773,000 2,498,000 2,411,000 2,358,000 5,732,000 5,722,000 5,251,000 4,467,000 1,800,000                           
      operating lease liabilities, net of current portion
    		36,171,000 44,232,000 43,092,000 43,237,000 12,400,000 13,553,000 8,058,000 7,525,000 8,720,000 9,891,000 9,709,000 10,648,000 11,527,000 12,529,000 13,485,000 14,096,000                              
      other liabilities
    		 508,000 446,000 411,000 571,000 540,000 528,000 786,000 776,000 792,000 791,000 931,000 1,148,000 1,210,000 1,378,000 1,407,000 1,891,000                             
      total liabilities
    		110,120,000 123,047,000 120,475,000 124,069,000 98,979,000 101,804,000 81,424,000 70,804,000 70,884,000 78,396,000 75,860,000 81,222,000 77,780,000 80,047,000 88,399,000 91,311,000 79,276,000 56,258,000 50,905,000 35,931,000 31,426,000 30,590,000 36,678,000 35,757,000 29,283,000 28,137,000 39,765,000 40,883,000 39,660,000 39,655,000 41,182,000 41,444,000 40,843,000 40,503,000 39,256,000 41,453,000 39,645,000 41,079,000 40,961,000 23,042,000 17,415,000 19,981,000 22,725,000 22,164,000 21,124,000 
      commitments and contingencies
    		                                             
      stockholders’ equity:
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of september 30, 2025 and december 31, 2024
    		                                             
      common stock
    		79,000 79,000 78,000 78,000 77,000 77,000 76,000 73,000 73,000 73,000 72,000 72,000 72,000 72,000 71,000 71,000 71,000 67,000 67,000 58,000 58,000 50,000 50,000 50,000 49,000 48,000 42,000 41,000 41,000 34,000 34,000 34,000 34,000 34,000 34,000 34,000 28,000 28,000 28,000 27,000 27,000 23,000 21,000 21,000 1,000 
      additional paid-in capital
    		1,684,587,000 1,670,853,000 1,660,435,000 1,655,961,000 1,646,343,000 1,627,307,000 1,617,465,000 1,536,168,000 1,528,011,000 1,520,638,000 1,509,861,000 1,500,191,000 1,492,044,000 1,483,279,000 1,477,418,000 1,468,683,000 1,461,778,000 1,303,610,000 1,297,626,000 702,768,000 696,217,000 495,523,000 488,773,000 486,090,000 470,202,000 462,689,000 319,733,000 313,800,000 310,357,000 252,284,000 250,238,000 248,278,000 245,430,000 243,409,000 241,617,000 239,631,000 205,658,000 203,769,000 202,079,000 198,497,000 196,829,000 157,688,000 143,982,000 142,592,000 3,181,000 
      accumulated deficit
    		-418,779,000 -437,916,000 -436,936,000 -443,983,000 -449,096,000 -464,251,000 -469,985,000 -468,121,000 -439,828,000 -410,210,000 -401,808,000 -393,717,000 -389,873,000 -381,150,000 -371,618,000 -357,157,000 -346,629,000 -332,500,000 -323,462,000 -281,594,000 -273,550,000 -269,426,000 -258,401,000 -246,685,000 -239,227,000 -238,497,000 -236,003,000 -234,086,000 -230,981,000 -226,512,000 -220,264,000 -211,087,000 -202,648,000 -195,599,000 -188,301,000 -180,084,000 -175,681,000 -170,044,000        
      accumulated other comprehensive loss
    		-8,220,000 -11,959,000 -28,641,000 -36,090,000 -21,282,000 -30,610,000 -28,907,000 -24,018,000 -34,197,000 -27,783,000 -26,866,000 -31,346,000 -54,066,000 -38,050,000 -20,681,000 -15,083,000 -8,140,000                             
      total stockholders’ equity
    		1,257,667,000 1,221,057,000 1,194,936,000  1,176,042,000 1,132,523,000 1,118,649,000  1,054,059,000 1,082,718,000 1,081,259,000  1,048,177,000 1,064,151,000 1,085,190,000  1,107,080,000 971,177,000 974,231,000  422,725,000 226,147,000 230,422,000  231,024,000 224,240,000 83,772,000  79,417,000 25,806,000 30,008,000  42,816,000 47,844,000 53,350,000  30,005,000 33,753,000 43,306,000 57,811,000 65,088,000 35,079,000 45,025,000 50,290,000  
      total liabilities and stockholders’ equity
    		1,367,787,000 1,344,104,000 1,315,411,000  1,275,021,000 1,234,327,000 1,200,073,000  1,124,943,000 1,161,114,000 1,157,119,000  1,125,957,000 1,144,198,000 1,173,589,000  1,186,356,000 1,027,435,000 1,025,136,000  454,151,000 256,737,000 267,100,000  260,307,000 252,377,000 123,537,000  119,077,000 65,461,000 71,190,000  83,659,000 88,347,000 92,606,000  69,650,000 74,832,000 84,267,000 80,853,000 82,503,000 55,060,000 67,750,000 72,454,000  
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of june 30, 2025 and december 31, 2024
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of march 31, 2025 and december 31, 2024
    		                                             
      liabilities and stockholders' equity
    		                                             
      deferred tax liability
    		   1,227,000    734,000    4,531,000    5,592,000 6,234,000 773,000 750,000                     222,000 254,000 300,000    
      stockholders' equity:
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of december 31, 2024 and 2023
    		                                             
      total stockholders' equity
    		   1,175,966,000    1,044,102,000    1,075,200,000    1,096,514,000    421,232,000    239,455,000    79,755,000    37,225,000    59,581,000          
      total liabilities and stockholders' equity
    		   1,300,035,000    1,114,906,000    1,156,422,000    1,187,825,000    457,163,000    275,212,000    120,638,000    78,669,000    101,034,000          
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of september 30, 2024 and december 31, 2023
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of june 30, 2024 and december 31, 2023
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of march 31, 2024 and december 31, 2023
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of december 31, 2023 and 2022
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of september 30, 2023 and december 31, 2022
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of june 30, 2023 and december 31, 2022
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of march 31, 2023 and december 31, 2022
    		                                             
      property and equipment
    		           17,702,000 17,237,000 17,188,000 16,299,000 15,098,000 14,868,000 11,813,000 10,562,000 8,990,000 8,914,000 8,640,000 8,788,000 8,933,000 8,488,000 8,150,000 8,114,000 8,940,000 8,939,000 9,035,000 9,215,000 9,688,000 10,281,000 10,093,000 10,657,000 11,480,000 10,435,000 10,937,000 11,272,000 6,200,000 4,211,000 4,132,000 3,312,000 3,028,000 2,826,000 
      right-of-use assets - operating leases
    		           13,160,000    16,043,000                              
      current portion of long-term debt
    		            1,187,000 1,133,000 1,079,000 1,127,000            1,357,000               940,000 467,000  
      deferred revenue, net of current portion
    		              278,000 343,000 552,000 662,000 747,000 829,000                          
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of december 31, 2022 and 2021
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of september 30, 2022 and december 31, 2021
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of june 30, 2022 and december 31, 2021
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of march 31, 2022 and december 31, 2021
    		                                             
      supplies
    		               11,225,000 9,824,000 6,674,000 6,308,000 4,657,000 4,456,000 7,041,000 6,094,000 6,806,000 6,608,000 5,104,000 3,768,000 3,402,000 3,463,000                 
      long-term debt
    		                1,075,000 917,000 863,000 810,000 756,000 801,000 748,000 694,000 639,000 585,000 12,854,000 23,925,000 25,192,000 25,103,000 25,016,000 24,938,000 24,997,000 24,971,000 24,944,000 24,918,000 24,891,000 24,671,000 24,452,000 5,002,000 4,975,000 4,949,000    
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of december 31, 2021 and 2020
    		                                             
      right-of-use assets, operating lease
    		                16,001,000 14,559,000                            
      current portion of operating lease liability
    		                3,465,000 2,936,000 2,878,000 1,589,000 1,542,000 1,495,000 1,450,000 1,407,000 1,365,000 1,284,000 1,244,000                   
      operating lease liability, net of current portion
    		                14,236,000 13,334,000 14,036,000 9,917,000 10,331,000 10,736,000 11,132,000 11,506,000 11,872,000 12,231,000 12,582,000                   
      preferred stock, 0.001 par value; 5,000,000 shares authorized, 0 shares issued and outstanding as of september 30, 2021 and december 31, 2020
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, 0 shares issued and outstanding as of june 30, 2021 and december 31, 2020
    		                                             
      right-of-use assets - operating lease
    		                  15,186,000 7,843,000 8,094,000 8,339,000 8,576,000 8,808,000 9,033,000 9,412,000 9,630,000                   
      current portion of acquisition related contingent consideration
    		                  5,986,000                           
      preferred stock, 0.001 par value; 5,000,000 shares authorized, 0 shares issued and outstanding as of march 31, 2021 and december 31, 2020
    		                                             
      finite-lived intangible assets
    		                   59,924,000 61,197,000 62,471,000 63,744,000 65,019,000 11,200,000 11,467,000 11,733,000 12,000,000 12,267,000 12,533,000 12,800,000 13,067,000 13,333,000 13,600,000 13,867,000 14,133,000 14,400,000 14,666,000 14,933,000 15,467,000 15,733,000     
      acquisition related contingent consideration
    		                   7,594,000    6,088,000                      
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of december 31, 2020 and 2019
    		                                             
      acquisition-related contingent consideration
    		                    6,420,000 5,948,000 5,604,000                       
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of september 30, 2020 and december 31, 2019
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of june 30, 2020 and december 31, 2019
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of march 31, 2020 and december 31, 2019
    		                                             
      deferred rent, net of current portion
    		                           3,899,000 3,953,000 4,005,000 4,094,000 4,170,000 4,245,000 4,277,000 4,373,000 4,402,000 4,484,000 4,566,000 4,630,000 2,386,000 384,000 111,000 223,000 260,000 250,000 
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of december 31, 2019 and 2018
    		                                             
      right-of-use assets - finance lease
    		                        619,000 677,000 735,000                   
      current portion of finance lease liability
    		                        79,000 156,000 233,000                   
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of september 30, 2019 and december 31, 2018
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of june 30, 2019 and december 31, 2018
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of march 31, 2019 and december 31, 2018
    		                                             
      capital lease liability, net of current portion
    		                            79,000 156,000 233,000 308,000 382,000 456,000 528,000 599,000          
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of december 31, 2018 and 2017
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of september 30, 2018 and december 31, 2017
    		                                             
      supplies inventory
    		                             3,049,000 4,557,000 5,324,000 3,760,000 3,317,000 3,443,000 3,475,000 3,416,000 3,502,000 3,652,000 3,984,000 3,976,000 3,732,000 3,300,000 2,721,000 1,392,000 
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of june 30, 2018 and december 31, 2017
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of march 31, 2018 and december 31, 2017
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of december 31, 2017 and 2016
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of september 30, 2017 and december 31, 2016
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of june 30, 2017 and december 31, 2016
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of march 31, 2017 and december 31, 2016
    		                                             
      deferred genzyme co-promotion fee
    		                                     227,000 518,000 1,423,000 1,897,000 1,897,000 2,500,000 2,500,000 2,500,000 
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of december 31, 2016 and 2015
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of september 30, 2016 and december 31, 2015
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of june 30, 2016 and december 31, 2015
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of march 31, 2016 and december 31, 2015
    		                                             
      deferred tax asset
    		                                       222,000 254,000 300,000    
      indefinite-lived intangible assets: in-process research and development
    		                                             
      deferred genzyme co-promotion fee, net of current portion
    		                                         474,000 1,364,000 1,989,000 3,239,000 
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of september 30, 2015 and december 31, 2014
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of june 30, 2015 and december 31, 2014
    		                                             
      in-process research and development
    		                                         16,000,000    
      preferred stock, 0.001 par value; 5,000,000 shares authorized, no shares issued and outstanding as of march 31, 2015 and december 31, 2014
    		                                             
      long-term debt, net of current portion
    		                                          4,031,000 4,467,000  
      preferred stock, 0.001 par value; 5,000,000 shares authorized, 0 shares issued and outstanding as of june 30, 2014 and december 31, 2013, respectively
    		                                             
      preferred stock, 0.001 par value; 5,000,000 shares authorized, 0 shares issued and outstanding as of march 31, 2014 and december 31, 2013, respectively
    		                                             
      liabilities, convertible preferred stock, and stockholders’ (deficit) equity
    		                                             
      preferred stock liability
    		                                             
      long-term debt, net of discount
    		                                            4,863,000 
      preferred stock warrant liability
    		                                            252,000 
      convertible preferred stock; 0.001 par value, 60,187,700 and 59,147,999 shares authorized at september 30, 2013 (unaudited) and december 31, 2012, respectively; 59,989,268 and 53,084,507 shares issued and outstanding at september 30, 2013 (unaudited) and december 31, 2012, respectively
    		                                            79,022,000 
      stockholders’ (deficit) equity:
    		                                             
      total stockholders’ (deficit) equity
    		                                             
      total liabilities, convertible preferred stock, and stockholders’ (deficit) equity
    		                                            23,571,000 
    The information provided in this report is taken from www.sec.gov and many other data providers. While we have conducted our best efforts to ensure that the parsed data is accurate, we cannot guarantee its accuracy. Please use caution and understand that any consequences of its use are your own responsibility.