7Baggers

Sarepta Therapeutics Quarterly Income Statements Chart

Quarterly
 | 
Annual
 
 Revenue  
 Gross Profit  
 Operating Profit  
 Net Income  
20200930 20201231 20210331 20210630 20210930 20211231 20220331 20220630 20220930 20221231 20230331 20230630 20230930 20231231 20240331 20240630 20240930 20241231 20250331 20250630 -516.75-336.52-156.2923.94204.17384.4564.63744.86Milllion

Sarepta Therapeutics Quarterly Income Statements Table

Quarterly
 | 
Annual
 
Unit: USD2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 2014-06-30 2014-03-31 2013-12-31 2013-09-30 2013-07-22 2013-06-30 2012-12-31 2012-09-30 2012-07-22 2011-12-31 2011-07-22 2011-06-30 2011-03-31 2010-12-31 2010-09-30 2010-07-22 2010-06-30 2010-03-31 2009-12-31 2009-09-30 2009-07-22 2009-07-22 2009-06-30 2009-03-31 2008-12-31 2008-09-30 2008-07-22 2008-06-30 2007-07-22 2007-07-22 2006-07-22 2005-12-31 2005-07-22 2005-06-30 2004-12-31 2004-09-30 2004-07-22 2004-03-31 2003-09-30 2003-07-22 2003-07-22 2002-07-22 2002-07-22 2002-06-30 2002-03-31 2001-12-31 2001-09-30 2001-07-22 
                                                                                              
  revenues:                                                                                            
  products513,123,000 611,523,000 638,157,000 429,771,000 360,548,000 359,484,000 365,071,000 309,322,000 238,988,000 231,495,000 235,933,000 207,774,000 211,237,000 188,825,000 178,725,000 166,911,000 141,839,000 124,926,000 122,644,000 121,429,000 111,344,000 100,448,000                                                                       
  collaboration and other97,968,000 133,333,000 20,255,000 37,401,000 2,383,000 53,980,000                                                                                       
  total revenues611,091,000 744,856,000 658,412,000 467,172,000 362,931,000 413,464,000 396,781,000 331,817,000 261,238,000 253,500,000 258,427,000 230,269,000 233,487,000 210,830,000 201,461,000 189,406,000 164,089,000 146,931,000 145,138,000 143,924,000 137,363,000 113,674,000 100,113,000 99,041,000 94,668,000 87,011,000 84,415,000 78,486,000 73,529,000 64,604,000 57,277,000 45,954,000 35,011,000 16,342,000                                                           
  yoy68.38% 80.15% 65.94% 40.79% 38.93% 63.10% 53.54% 44.10% 11.89% 20.24% 28.28% 21.57% 42.29% 43.49% 38.81% 31.60% 19.46% 29.26% 44.97% 45.32% 45.10% 30.64% 18.60% 26.19% 28.75% 34.68% 47.38% 70.79% 110.02% 295.32%                                                               
  qoq-17.96% 13.13% 40.94% 28.72% -12.22% 4.20% 19.58% 27.02% 3.05% -1.91% 12.23% -1.38% 10.75% 4.65% 6.36% 15.43% 11.68% 1.24% 0.84% 4.78% 20.84% 13.55% 1.08% 4.62% 8.80% 3.08% 7.55% 6.74% 13.81% 12.79% 24.64% 31.26% 114.24%                                                            
  cost and expenses:                                                                                            
  cost of sales152,558,000 137,564,000 132,304,000 91,691,000 44,545,000 50,559,000 44,176,000 37,026,000 34,124,000 35,017,000 30,799,000 39,952,000 37,795,000 31,443,000 31,744,000 23,444,000 19,515,000 22,346,000 22,404,000 15,015,000 13,341,000 12,622,000 15,567,000 13,037,000 15,919,000 12,063,000 13,135,000 8,741,000 6,735,000 5,582,000 3,546,000 3,078,000 534,000 252,000                                                           
  gross profit458,533,000 607,292,000 526,108,000 375,481,000 318,386,000 362,905,000 352,605,000 294,791,000 227,114,000 218,483,000 227,628,000 190,317,000 195,692,000 179,387,000 169,717,000 165,962,000 144,574,000 124,585,000 122,734,000 128,909,000 124,022,000 101,052,000 84,546,000 86,004,000 78,749,000 74,948,000 71,280,000 69,745,000 66,794,000 59,022,000 53,731,000 42,876,000 34,477,000 16,090,000                                                           
  yoy44.02% 67.34% 49.21% 27.37% 40.19% 66.10% 54.90% 54.89% 16.06% 21.79% 34.12% 14.68% 35.36% 43.99% 38.28% 28.74% 16.57% 23.29% 45.17% 49.89% 57.49% 34.83% 18.61% 23.31% 17.90% 26.98% 32.66% 62.67% 93.73% 266.82%                                                               
  qoq-24.50% 15.43% 40.12% 17.93% -12.27% 2.92% 19.61% 29.80% 3.95% -4.02% 19.60% -2.75% 9.09% 5.70% 2.26% 14.79% 16.04% 1.51% -4.79% 3.94% 22.73% 19.52% -1.70% 9.21% 5.07% 5.15% 2.20% 4.42% 13.17% 9.85% 25.32% 24.36% 114.28%                                                            
  gross margin %75.04% 81.53% 79.91% 80.37% 87.73% 87.77% 88.87% 88.84% 86.94% 86.19% 88.08% 82.65% 83.81% 85.09% 84.24% 87.62% 88.11% 84.79% 84.56% 89.57% 90.29% 88.90% 84.45% 86.84% 83.18% 86.14% 84.44% 88.86% 90.84% 91.36% 93.81% 93.30% 98.47% 98.46%                                                           
  research and development204,392,000 773,448,000 199,953,000 224,483,000 179,690,000 200,396,000 195,517,000 194,301,000 241,890,000 245,679,000 213,804,000 216,707,000 252,329,000 194,250,000 197,296,000 139,115,000 239,622,000 195,149,000 207,239,000 190,438,000 188,522,000 136,144,000 223,141,000 133,949,000 113,266,000 90,553,000 146,207,000 86,584,000 122,848,000 46,204,000 44,441,000 34,239,000 58,908,000 29,119,000 70,749,000 34,349,000 44,348,000 38,826,000 41,376,000 36,673,000 29,180,000 39,165,000 30,832,000 21,852,000 20,641,000 20,906,000 410,744,000 21,087,000 13,762,000 12,984,000 346,100,000 10,914,000 14,805,000 285,105,000 15,610,000 17,750,000 14,801,000 244,324,000 9,059,000 9,059,000 6,931,000 6,096,000 6,625,000 7,473,000   5,804,000 4,495,000 5,430,109 7,934,886 7,472,811 8,164,698   6,763,245 4,913,490 4,147,201 3,915,155 3,805,658 4,167,209 97,211,010 6,613,988 3,533,868     7,224,095 7,049,120 38,216,603 2,774,979 36,588,578 
  selling, general and administrative137,897,000 133,629,000 163,873,000 128,200,000 138,796,000 127,003,000 131,700,000 120,893,000 118,564,000 110,714,000 120,478,000 104,787,000 154,316,000 71,840,000 78,055,000 61,127,000 72,347,000 71,131,000 86,046,000 75,373,000 73,688,000 82,768,000 81,424,000 75,429,000 67,393,000 60,566,000 64,220,000 53,044,000 47,156,000 43,341,000 32,221,000 28,176,000 36,069,000 26,216,000                                                           
  amortization of in-licensed rights667,000 601,000 601,000 602,000 601,000 601,000 763,000 439,000 179,000 178,000 179,000 178,000 179,000 178,000 179,000 178,000 179,000 170,000 165,000 166,000 165,000 166,000 200,000 216,000 217,000 216,000 216,000 216,000 217,000 216,000 216,000 780,000                                                             
  total cost and expenses495,514,000 1,045,242,000 496,731,000 444,976,000 363,632,000 378,559,000 372,156,000 352,659,000 394,757,000 391,588,000 365,260,000 361,624,000 444,619,000 297,711,000 307,274,000 223,864,000 331,663,000 298,796,000 315,854,000 280,992,000 275,716,000 231,700,000 330,332,000 222,631,000 370,035,000 163,398,000     80,424,000 91,861,000 98,350,000 55,587,000                                                           
  operating income115,577,000 -300,386,000 161,681,000 22,196,000 -701,000 34,905,000 24,625,000 -20,842,000 -133,519,000 -138,088,000 -106,833,000 -131,355,000 -211,132,000 -86,881,000 -105,813,000 -34,458,000 -167,574,000 -151,865,000 -170,716,000 -137,068,000 -138,353,000 -118,026,000 -230,219,000 -123,590,000 -275,367,000 -76,387,000 -139,363,000 -70,099,000 -103,427,000 -30,739,000 -23,147,000 -45,907,000 -63,339,000 -39,245,000 -88,395,000 -56,533,000 -62,100,000 -59,702,000 -64,452,000 -51,763,000 -42,107,000 -61,862,000 -44,722,000 -33,675,000 -30,271,000 -25,121,000 -393,517,000 -24,933,000 -15,415,000 -17,087,000 -341,332,000 -6,905,000 -6,874,000 -304,038,000 -11,271,000 -10,125,000 -5,531,000                                    
  yoy-16587.45% -960.58% 556.57% -206.50% -99.47% -125.28% -123.05% -84.13% -36.76% 58.94% 0.96% 281.20% 25.99% -42.79% -38.02% -74.86% 21.12% 28.67% -25.85% 10.91% -49.76% 54.51% 65.19% 76.31% 166.24% 148.50% 502.08% 52.70% 63.29% -21.67% -73.81% -18.80% 2.00% -34.27% 37.15% 9.22% 47.48% -3.49% 44.12% 53.71% 39.10% 146.26% -88.64% 35.06% 96.37% 47.02% 15.29% 261.09% 124.25% -94.38% 2928.41% -31.80% 24.28%                                        
  qoq-138.48% -285.79% 628.42% -3266.33% -102.01% 41.75% -218.15% -84.39% -3.31% 29.26% -18.67% -37.79% 143.01% -17.89% 207.08% -79.44% 10.34% -11.04% 24.55% -0.93% 17.22% -48.73% 86.28% -55.12% 260.49% -45.19% 98.81% -32.22% 236.47% 32.80% -49.58% -27.52% 61.39% -55.60% 56.36% -8.96% 4.02% -7.37% 24.51% 22.93% -31.93% 38.33% 32.80% 11.25% 20.50% -93.62% 1478.30% 61.75% -9.79% -94.99% 4843.26% 0.45% -97.74% 2597.52% 11.32% 83.06%                                     
  operating margin %18.91% -40.33% 24.56% 4.75% -0.19% 8.44% 6.21% -6.28% -51.11% -54.47% -41.34% -57.04% -90.43% -41.21% -52.52% -18.19% -102.12% -103.36% -117.62% -95.24% -100.72% -103.83% -229.96% -124.79% -290.88% -87.79% -165.09% -89.31% -140.66% -47.58% -40.41% -99.90% -180.91% -240.15%                                                           
  other income, net:                                                                                            
  other income38,061,000 -83,132,000 10,062,000 11,810,000 14,278,000 6,543,000 15,746,000 -12,332,000 16,934,000 12,707,000 5,527,000 -6,322,000 -16,961,000 -17,265,000 -16,076,000 -20,649,000 -16,185,000 -15,528,000 -17,769,000 -14,335,000 -12,447,000 -7,420,000 -4,773,000 -2,510,000 -862,000  -4,167,750 -6,968,000 -5,218,000 -4,485,000                                   4,495,000 4,495,000       6,317,641 6,317,641          2,805,895 2,805,895 65,614,102 65,614,102      
  income before income tax expense153,638,000 -383,518,000 171,743,000 34,006,000 13,577,000 41,448,000 -140,117,250 -33,174,000 -14,585,000 -512,710,000         -91,145,000 -196,403,000 -150,800,000 -17,377,000 -119,722,000 -126,100,000 -276,229,000 -76,559,000    -35,224,000 -25,840,000 -45,723,000  86,090,000                                                           
  income tax (benefit) expense-43,254,000                -354,000 -143,000         -779,000 -674,000     -109,000                                                            
  net income196,892,000 -447,508,000 159,049,000 33,611,000 6,460,000 36,119,000 45,655,000 -40,937,000 -23,940,000 -516,755,000 -109,244,000 -257,738,000 -231,481,000 -105,025,000 -121,981,000 -48,144,000 -81,405,000 -167,250,000 -189,317,000 -196,499,000 -150,820,000 -17,492,000 -235,703,000 -126,326,000 -276,403,000 -76,643,000 -140,895,000 -76,393,000 -109,267,000 -35,363,000 -23,998,000 -47,734,000 -63,046,000 84,090,000 -88,452,000 -56,742,000 -62,301,000 -59,770,000 -64,681,000 -51,939,000 -41,851,000 -61,559,000 -44,416,000 -29,226,000 -33,874,000 -28,273,000 -440,071,000 -42,030,000 -42,084,000 -19,051,000 -372,031,000 -49,554,000 -17,704,000    1,833,000     -584,000 3,525,000 -8,090,000   -19,668,000 -927,000 -1,140,534 -6,046,993 -15,014,476 -1,750,622   -9,061,150 -4,551,572 -1,692,471 -4,932,642 -4,990,254 -5,106,966 -145,875,160 -7,532,512 -4,603,655     -10,497,859 -7,816,093 -64,898,088 -15,596,194 -63,472,543 
  yoy2947.86% -1338.98% 248.37% -182.10% -126.98% -106.99% -141.79% -84.12% -89.66% 392.03% -10.44% 435.35% 184.36% -37.20% -35.57% -75.50% -46.03% 856.15% -19.68% 55.55% -45.43% -77.18% 67.29% 65.36% 152.96% 116.73% 487.11% 60.04% 73.31% -142.05% -72.87% -15.88% 1.20% -240.69% 36.75% 9.25% 48.86% -2.91% 45.63% 77.72% 23.55% 117.73% -89.91% -30.46% -19.51% 48.41% 18.29% -15.18% 137.71%    -1065.85%          -117.92% 772.71%   30.99% -47.05%   65.70% -61.54%   81.58% -10.88% -98.84% -34.52% 8.40%         -83.46%     
  qoq-144.00% -381.36% 373.21% 420.29% -82.11% -20.89% -211.53% 71.00% -95.37% 373.03% -57.61% 11.34% 120.41% -13.90% 153.37% -40.86% -51.33% -11.66% -3.65% 30.29% 762.22% -92.58% 86.58% -54.30% 260.64% -45.60% 84.43% -30.09% 208.99% 47.36% -49.73% -24.29% -174.97% -195.07% 55.88% -8.92% 4.23% -7.59% 24.53% 24.10% -32.01% 38.60% 51.97% -13.72% 19.81% -93.58% 947.04% -0.13% 120.90% -94.88% 650.76% 179.90%          -116.57% -143.57%    2021.68% -18.72% -81.14% -59.73% 757.67%    99.08% 168.93% -65.69% -1.15% -2.29% -96.50% 1836.61% 63.62%      34.31% -87.96% 316.11% -75.43%  
  net income margin %32.22% -60.08% 24.16% 7.19% 1.78% 8.74% 11.51% -12.34% -9.16% -203.85% -42.27% -111.93% -99.14% -49.82% -60.55% -25.42% -49.61% -113.83% -130.44% -136.53% -109.80% -15.39% -235.44% -127.55% -291.97% -88.08% -166.91% -97.33% -148.60% -54.74% -41.90% -103.87% -180.07% 514.56%                                                           
  other comprehensive income:                                                                                            
  unrealized gains on investments, net of tax-85,000 252,000 -2,463,000 3,275,000 -339,000 -1,609,000 1,556,000 417,000 -636,000 1,245,000   -2,179,000    5,000 -6,000 -14,000 -12,000 -618,000 574,000                                                                       
  total other comprehensive income-85,000 252,000 -2,463,000 3,275,000 -339,000 -1,609,000 1,556,000 417,000 -636,000 1,245,000        -6,000 9,000 -12,000 -618,000 574,000 -25,000 -7,000 63,000 118,000 96,750 369,000 282,000 -264,000 27,000 26,000 17,000 65,000 27,750 -1,000 6,000 106,000 23,500 18,000 -2,000    24,000                                                
  comprehensive income196,807,000 -447,256,000 156,586,000 36,886,000 6,121,000 34,510,000                       -108,985,000 -35,627,000   -63,029,000 84,155,000                -19,051,000 -14,805,000 -49,554,000 -17,704,000                                        
  earnings per share:                                                                                            
  basic2.01 -4.6 1.67 0.35 0.07 0.38                                                                                       
  diluted1.89 -4.6 1.56 0.34 0.07 0.37                                                                                       
  weighted-average number of shares of common stock used in computing earnings per share:                                                                                            
  basic98,005 97,362 95,075 95,390 94,618 93,991                                                                                       
  diluted106,623 97,362 107,875 100,448 99,144 99,114                                                                                       
  income tax expense 63,990,000 12,694,000 395,000 7,117,000 5,329,000 5,290,750 7,763,000 9,355,000 4,045,000         57,750 96,000 20,000 115,000   174,000 84,000    139,000 -1,842,000 2,011,000  2,000,000                                                           
  gain from sale of priority review voucher        102,000,000        102,000,000     108,069,000            125,000,000                               -927,000 -927,000       -9,722,975 -9,722,975          -3,418,817 -3,418,817 -112,584,224 -112,584,224      
  loss on debt extinguishment         -387,329,000  -125,441,000                                                                                 
  total other income  10,062,000 11,810,000 14,278,000 6,543,000   118,934,000  5,527,000 -125,063,000 -16,961,000  -16,076,000 -13,449,000 85,815,000 -15,528,000 -17,769,000 -59,335,000 -12,447,000 100,649,000         -2,693,000 184,000 184,000 125,335,000 -57,000 -209,000 -201,000 -68,000 -229,000 -176,000 256,000 303,000 -576,500 4,449,000                                                 
  collaboration      16,687,500 22,495,000 22,250,000 22,005,000 16,687,500 22,495,000 22,250,000 22,005,000 16,687,500 22,495,000 22,250,000 22,005,000 22,494,000 22,495,000 26,019,000 13,226,000                                                                       
  other loss, net:                                                                                            
  total other loss      -67,005,000 -12,332,000  -374,622,000    -17,265,000                               -3,603,000 -3,152,000 -11,432,500 -17,097,000                                             
  comprehensive loss      47,211,000 -40,520,000 -24,576,000 -515,510,000 -107,703,000 -258,458,000 -233,660,000 -105,311,000 -121,981,000 -48,166,000 -81,400,000 -167,256,000 -189,308,000 -196,511,000 -151,438,000 -16,918,000 -235,728,000 -126,333,000 -276,340,000 -76,525,000 -141,002,000 -76,024,000   -24,365,000 -47,708,000   -88,572,000 -56,743,000 -62,295,000 -59,664,000 -64,791,000 -51,921,000 -41,853,000 -61,481,000 -44,456,000 -29,247,000 -33,850,000 -28,332,000 -440,071,000 -42,030,000 -42,084,000                                            
  net income per share      0.76 -0.46 -0.27 -5.86 -1.24 -2.94 -2.65 -1.2 -1.43 -0.6 -1.02 -2.1 -2.41 -2.5 -1.93 -0.23 -3.17 -1.7 -3.74 -1.07 -2.08 -1.15   -0.39 -0.78   -1.66 -1.18 -1.35 -1.31 -1.45 -1.25  -1.49 -1.08 -0.71 -0.85 -0.75 -0.793 -1.24 -1.32 -0.6 -0.653 -2.17 -0.13 -0.003 -0.03 0.01 0.02 -0.055 -0.07 -0.07 -0.15 -0.01 0.06 -0.08   -0.23 -0.01 -0.01 -0.08 -0.23 -0.02   -0.18 -0.09 -0.04 -0.11 -0.14 -0.14  -0.21 -0.15     -0.4 -0.33 -0.253 -0.67  
  weighted-average number of shares of common stock used in computing basic and diluted net income per share      92,398 88,889 88,743 88,186 87,559 87,628 87,511 87,253 81,262 79,880 79,746 79,454 77,956 78,501 77,968 76,432 73,615 74,177 73,958 71,731  66,209                                                                 
  settlement and license charges                 10,000,000              25,588,000                                                             
  gain on contingent consideration           6,700,000    7,200,000                                                                             
  income before income tax benefit          -101,306,000 -256,418,000 -228,093,000 -104,146,000 -74,264,750 -47,907,000             -108,645,000                                                                
  income tax benefit          7,938,000 1,320,000 3,388,000 879,000 -65,000 237,000       711,000 226,000     622,000                                                                
  other comprehensive loss:                                                                                            
  unrealized losses on investments, net of tax          1,541,000 -720,000  -286,000 -5,750 -22,000                                                                             
  total other comprehensive loss          1,541,000 -720,000 -2,179,000 -286,000 -5,750 -22,000 5,000                          -40,000 -21,000  -59,000                                               
  other income:                                                                                            
  income before income tax (benefit) expense                -81,759,000 -167,393,000         -141,674,000 -77,067,000     -63,155,000                                                            
  acquired in-process research and development                        173,240,000                          29,461,000                  9,916,271          19,545,028           19,545,028 
  loss on contingent consideration                   -45,000,000                                             -0.01 -0.01       -0.18 -0.18          -0.13 -0.13        
  product                      100,113,000 99,041,000 94,668,000 87,011,000 84,415,000 78,486,000 73,529,000 64,604,000 57,277,000 45,954,000 35,011,000 16,342,000                                                           
  other loss:                                                                                            
  other loss                      -886,000 -2,510,000 -862,000 -172,000                                                                   
  unrealized gains on investments                      -25,000 -7,000 63,000                                                                    
  interest expense and other                         -172,000                                                                   
  unrealized gain on cash equivalents and short-term investments                         118,000 96,750 369,000 282,000 -264,000 27,000 26,000                                                             
  costs and expenses:                                                                                            
  exondys 51 litigation and license charges                                2,839,000                                                            
  total costs and expenses                          105,221,000 148,585,000 176,956,000 95,343,000                                                               
  interest income and other                          -4,167,750 -6,968,000 -5,218,000 -4,485,000 -2,693,000 184,000 184,000 335,000 -57,000 -209,000 -201,000 -68,000 -229,000 -176,000 256,000 303,000 306,000 193,000 181,000 99,000 9,568,000 63,000 237,000 -19,000 9,253,000 67,000 96,000 8,729,000 199,000 151,000 90,000 8,412,000 82,000 82,000 51,000 42,000      16,000                         
  basic earnings per share                            -1.67 -0.55   -1.15 1.53                                                    19,545,028 19,545,028      
  diluted earnings per share                            -1.67 -0.55   -1.15 1.5                                                           
  weighted-average number of shares of common stock used in computing:                                                                                            
  weighted-average number of shares of common stock outstanding for computing basic and diluted net income per share                          66,250    58,818 61,528   48,697 48,254 46,157 45,697 42,290 41,565 41,357                                                    
  unrealized gain on short-term securities - available-for-sale                                17,000 65,000 27,750 -1,000 6,000 106,000 23,500 18,000 -2,000                                                    
  weighted-average number of shares of common stock used in calculating:                                                                                            
  revenues                                                                                            
  operating expenses:                                                                                            
  general and administrative                                  15,203,000 22,184,000 17,752,000 20,876,000 24,329,000 15,090,000 12,927,000 22,697,000 13,917,000 12,882,000 12,213,000 10,303,000 129,486,000 8,014,000 6,127,000 7,054,000 109,326,000 3,565,000 3,281,000 92,286,000 3,185,000 3,960,000 5,026,000 77,385,000 3,440,000 3,440,000 4,733,000 2,844,000 2,470,000 1,800,000   2,206,000 2,220,000 2,943,530 3,173,942 1,982,679 1,696,796   2,821,726 1,409,066 1,052,244 1,272,529 1,416,803 964,700 25,503,904 1,238,201 1,560,026     895,706 1,084,519 12,275,514 877,615 12,433,101 
  total operating expenses                                  44,583,750 56,533,000 62,100,000 59,702,000 65,705,000 51,763,000 42,107,000 61,862,000                                                   
  revenue from research contracts and other grants                                          27,000 1,059,000 2,583,000                                                
  gain on change in warrant valuation                                          -694,750 4,256,000       -26,814,000 -42,716,000 -10,926,000            16,000 16,000                           
  loss on change in warrant valuation                                            -3,784,000 -3,251,000 -11,502,750 -17,160,000                                             
  loss per share — basic and diluted                                        -1.01                                                    
  unrealized gain on available-for-sale securities                                         78,000   24,000                                                
  total other comprehensive gain                                         78,000                                                   
  weighted-average number of common shares outstanding for computing basic and diluted net income per share                                         41,324    37,821   31,813                                            
  unrealized loss on available-for-sale securities                                          -13,750 -21,000  -59,000                                               
  weighted-average number of common stock outstanding for computing basic and diluted net income per share                                          40,026 41,066 39,862                                                
  revenue from license fees, grants and research contracts                                             6,088,000                                               
  realized gain on sale of available-for-sale securities                                                                2,220,000 2,220,000       4,303,885 4,303,885          933,401 933,401 17,816,311 17,816,311      
  write-down of available-for-sale securities                                                                                            
  revenues from license fees, grants and research contracts                                              176,174,000 4,168,000 4,474,000 2,951,000 143,555,000 7,574,000 11,212,000 102,814,000 7,524,000 11,585,000 14,296,000 75,326,000 8,702,000 8,702,000 3,997,000 1,205,000 5,141,000 6,349,000   2,945,000 3,150,000 5,479,912 5,170,663 5,624,617 4,982,963   65,962 1,417,446 3,281,805 39,317 285,588 9,151             
  realized gain on sale of short-term securities — available-for-sale                                                                                            
  write-down of short-term securities — available-for-sale                                                                                            
  unrealized loss on short-term securities — available-for-sale                                                                                            
  weighted-average number of common shares outstanding for computing basic net income per share                                               33,943                                             
  weighted-average number of common shares outstanding for computing diluted net income per share                                               33,943                                             
  other non-operating income:                                                                                            
  loss on change in warrant liability                                                -26,906,000                                            
  income on change in warrant valuation                                                 -1,945,000                                           
  weighted-average number of common shares outstanding for computing basic income per share                                                 31,984  22,824 135,743   134,090 112,482                                    
  weighted-average number of common shares outstanding for computing diluted income per share                                                 31,984  22,824 135,743   138,916 121,285                                    
  realized gain on sale of short-term securities— available-for-sale                                                                                           
  write-down of short-term securities— available-for-sale                                                               3,150,000 3,150,000       536,042 536,042                   
  unrealized loss on short-term securities— available-for-sale                                                                                           
  realized gain on sale of short-term securities - available-for-sale                                                                                           
  write-down of short-term securities - available-for-sale                                                                                           
  unrealized loss on short-term securities - available-for-sale                                                                                           
  increase on warrant valuation                                                     6,394,750 7,052,000 11,253,000 7,274,000     7,109,000                               
  realized gain on sale of short-term securities—available-for-sale                                                                                3,862,502            
  write-down of short-term securities—available-for-sale                                                                                            
  net income and comprehensive loss                                                     -227,000 -4,020,000   -6,133,250 -7,293,000 -7,293,000 -16,656,000                                
  weighted-average number of common shares outstanding for computing basic and diluted loss per share                                                      135,738    111,767 111,767 110,383 110,429 93,090 95,261   85,664 80,759 69,491,475 71,150,972 65,321,986 70,985,520   51,715,050 44,655,008 44,184,293 44,167,565 35,994,976 36,123,790  35,610,687 31,186,464     26,353,017 23,442,127  23,122,839  
  realized gain on sale of short-term—securitiesavailable-for-sale                                                                                            
  net income and comprehensive income                                                       1,279,000                                     
  gain on warrant liability                                                                   2,622,000 1,717,277   3,047,459                     
  interest income and other loss                                                                                            
  increase on warrant liability                                                                                            
  interest income                                                                    35,916 60,147 167,352 80,450   457,859 353,538 225,169 215,725 -53,381 15,792 4,736,599 220,226 75,887     111,207 79,851 2,608,443 271,939 2,842,879 
  revenues, from license fees, grants and research contracts                                                                                4,787,029 99,451 414,352     197,691  2,433,864 307,549 2,154,535 
  realized gain on sale of short-term securities                                                                                           96,750 
  write-down of short-term securities–available-for-sale                                                                                            
  revenues, from license fees, grants and                                                                                            
  research contracts                                                                                        237,695    
  write-down of short-term securities--available-for-sale                                                                80,759 80,759       53,241,730 53,241,730          26,567,968 26,567,968        
  3,556,746                                                                                           68,566,707 
  362,056                                                                                           2,939,629 

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