7Baggers
Quarterly
Annual
    Unit: USD2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 2014-06-30 2014-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31 2010-12-31 2010-09-30 2010-06-30 2010-03-31 2009-12-31 2009-09-30 2009-06-30 2009-03-31 2008-12-31 2008-09-30 2008-06-30 2008-03-31 2007-12-31 2007-09-30 2007-06-30 2007-03-31 2006-09-30 2006-06-30 2006-03-31 2005-12-31 2005-09-30 2005-06-30 2005-03-31 2004-12-31 2004-09-30 2004-06-30 2002-12-31 2001-12-31 2001-06-30 2001-03-31 
      
                                                                                             
      assets
                                                                                             
      current assets:
                                                                                             
      cash and cash equivalents
    613,077,000 510,598,000 240,867,000 1,103,010,000 197,855,000 383,622,000 427,290,000 428,430,000 541,932,000 851,929,000 871,668,000 966,777,000 1,038,624,000 868,565,000 1,233,877,000 2,115,869,000 1,599,113,000 1,697,275,000 1,481,836,000 1,502,648,000 1,474,637,000 1,639,959,000 1,764,212,000 835,080,000 724,829,000 808,591,000 732,190,000 370,829,000 209,702,000 410,375,000 557,234,000 599,691,000 617,630,000 168,348,000 274,723,000 122,420,000 395,140,000 111,819,000 38,001,000 80,304,000 55,819,000 69,538,000 74,436,000 73,551,000 52,299,000 102,754,000 49,101,000 256,965,000 273,644,000 156,185,000 167,919,000 187,661,000 37,987,000 24,491,000 30,573,000 39,904,000 46,356,000 54,188,000 23,283,000 33,589,000 35,967,000 36,742,000 41,438,000  50,268,000 20,037,000 24,723,000 11,192,238 14,081,213 18,509,474 19,960,809 24,802,562 3,861,272 9,263,512 14,964,915 25,578,248 31,764,383 36,867,301 34,597,734 27,556,780 27,346,075 34,356,842 16,654,829 12,341,849 11,044,909 10,384,963 11,069,451 28,132,365 22,001,736 
      short-term investments
    237,916,000 289,541,000 281,895,000 251,782,000 1,000,534,000 1,076,852,000 963,453,000 1,247,820,000 1,191,610,000 1,008,786,000 1,010,429,000 1,022,597,000 1,033,860,000 1,059,454,000 779,548,000   30,000,000 255,997,000 435,923,000 341,467,000 421,349,000 406,940,000 289,668,000 324,063,000 294,478,000 612,018,000 803,083,000 583,158,000 538,769,000 491,757,000 479,369,000  132,598,000 115,590,000 195,425,000  11,396,000 91,155,000 112,187,000 44,090,000 87,349,000 91,787,000 136,793,000 183,718,000 176,785,000 176,091,000                                           
      accounts receivable
    395,739,000 527,295,000 659,371,000 601,988,000 434,524,000 359,997,000 378,806,000 400,327,000 318,855,000 236,808,000 223,836,000 214,628,000 201,509,000 203,854,000 178,194,000 152,990,000 149,787,000 127,520,000 118,203,000 101,340,000 121,827,000 104,028,000 106,875,000 90,879,000 68,032,000 56,981,000 50,510,000 49,044,000 48,601,000 42,985,000 39,848,000 29,468,000 24,751,000 17,791,000 12,278,000 5,228,000 3,986,000 3,982,000 3,990,000 3,977,000 2,733,000 2,416,000 2,416,000 2,416,000 3,362,000 5,226,000 7,849,000 3,530,000 6,721,000 3,788,000 5,652,000 4,713,000 2,474,000 7,180,000 5,135,000 3,633,000 4,267,000 10,892,000 13,576,000 3,224,000 5,241,000 2,153,000 1,648,000  5,671,000 3,360,000 3,126,000 4,971,495 4,076,586 2,666,419 4,053,301 2,869,760 1,751,367 1,119,780 551,783 61,342 44,389 840,153 1,236,446           
      inventory
    1,077,166,000 994,036,000 941,432,000 749,960,000 565,924,000 485,795,000 373,530,000 322,859,000 244,011,000 226,876,000 202,675,000 203,968,000 221,192,000 208,095,000 198,997,000 186,212,000 288,469,000 268,756,000 240,333,000 231,961,000 220,118,000 179,650,000 173,168,000 171,379,000 166,360,000 156,569,000 140,467,000 125,445,000 115,816,000 104,126,000 99,375,000 83,605,000 64,693,000 41,754,000 30,445,000 12,813,000 2,921,000                                                     
      manufacturing-related deposits and prepaids
    206,062,000 207,921,000 203,490,000 276,262,000 321,055,000 302,627,000 238,821,000                                                                                   
      other current assets
    192,349,000 127,594,000 105,478,000 90,461,000 165,477,000 74,743,000 82,965,000 179,895,000 154,441,000 148,215,000 179,769,000 149,891,000 130,744,000 129,332,000 140,331,000 149,028,000 147,941,000 141,666,000 174,981,000 213,324,000 164,624,000 114,435,000 96,153,000 81,907,000 79,015,000 110,799,000 136,238,000 77,782,000 54,800,000 42,989,000 31,203,000 36,511,000 27,033,000 28,565,000 22,742,000 26,895,000 22,002,000 15,302,000 16,885,000 17,380,000 19,466,000 23,091,000 24,410,000 35,036,000 26,436,000 15,906,000 9,079,000 3,061,000 2,807,000 5,683,000 3,023,000 1,534,000 1,698,000 1,561,000 1,924,000 1,647,000 1,322,000 943,000 1,636,000 1,025,000 1,106,000 1,037,000 891,000  839,000 764,000 645,000 598,562 1,222,654 1,093,968 1,075,033 767,278 952,987 775,179 709,486 802,973 583,500 480,547 365,866 542,528 244,696 283,117 683,075 698,789 474,316 595,093 198,923 1,131,114 858,192 
      total current assets
    2,722,309,000 2,656,985,000 2,432,533,000 3,073,463,000 2,685,369,000 2,683,636,000 2,464,865,000 2,579,331,000 2,450,849,000 2,472,614,000 2,488,377,000 2,557,861,000 2,625,929,000 2,469,300,000 2,530,947,000 2,604,099,000 2,185,310,000 2,265,217,000 2,271,350,000 2,485,196,000 2,322,673,000 2,459,421,000 2,547,348,000 1,468,913,000 1,362,299,000 1,427,418,000 1,671,423,000 1,426,183,000 1,012,077,000 1,139,244,000 1,219,417,000 1,228,644,000 735,608,000 390,585,000 457,307,000 373,476,000 434,744,000 153,194,000 160,726,000 224,543,000 122,108,000 182,394,000 193,049,000 247,796,000 269,815,000 304,671,000 249,370,000 270,806,000 290,422,000 172,906,000 176,594,000 193,908,000 42,159,000 33,232,000 37,632,000 45,184,000 51,945,000 66,023,000 38,495,000 37,838,000 42,314,000 39,932,000 44,149,000  56,947,000 24,329,000 28,779,000 17,044,357 19,659,981 22,546,479 25,363,352 28,711,451 16,754,113 21,215,260 28,307,380 39,289,335 45,101,376 50,767,209 48,653,394 31,499,939 32,430,934 37,474,609 20,198,391 23,803,614 29,648,455 20,401,988 27,511,076 35,859,956 27,478,134 
      property and equipment
    358,936,000 371,857,000 360,587,000 340,336,000 305,788,000 276,200,000 249,302,000 227,154,000 212,367,000 188,874,000 182,862,000 180,037,000 181,005,000 183,292,000 187,248,000 191,156,000 199,249,000 203,330,000 203,107,000 190,430,000 171,715,000 153,340,000 137,325,000 129,620,000 119,532,000 117,201,000 106,280,000 97,024,000 76,841,000 57,624,000 53,927,000 43,156,000 38,872,000 39,393,000 38,412,000 37,801,000 35,620,000 36,158,000 36,982,000 37,344,000 37,379,000 37,196,000 37,759,000 38,501,000 37,178,000 20,163,000 20,130,000 15,049,000 8,244,000 3,359,000 3,088,000 3,397,000 3,661,000 3,898,000 4,105,000 4,265,000 2,445,000 2,363,000 2,111,000 2,070,000 2,155,000 2,184,000 2,361,000  2,102,000 4,758,000 4,934,000 5,188,984 6,277,736 6,474,073 6,677,465 6,825,145 7,099,321 7,189,503 4,103,482 4,745,658 4,935,608 5,153,921 5,599,269 5,887,787 6,007,775 6,143,778 6,313,644 6,588,211 6,565,275 6,584,290 4,897,788 2,423,962 1,993,383 
      right of use assets
    139,167,000 143,041,000 147,063,000 148,310,000 140,898,000 124,001,000 126,269,000 129,952,000 133,454,000 134,728,000 62,016,000 64,954,000 43,034,000 46,999,000 45,982,000 45,531,000 72,663,000 72,868,000 65,068,000 91,761,000 71,085,000 74,197,000 63,097,000 37,933,000                                                                  
      non-current inventory
    198,601,000 194,668,000 181,158,000 187,986,000 202,550,000 204,691,000 207,542,000 191,368,000 176,112,000 166,635,000 164,144,000                                                                               
      non-current investments
    1,040,000 34,604,000 109,125,000 133,163,000 181,770,000                                                                                     
      other non-current assets
    73,384,000 83,137,000 80,551,000 79,915,000 83,559,000 135,729,000 176,407,000 136,771,000 136,925,000 163,039,000 162,387,000 317,936,000 293,124,000 284,200,000 278,649,000 292,949,000 190,792,000 203,553,000 211,584,000 203,703,000 201,847,000 182,980,000 186,805,000 173,859,000         10,988,000 11,582,000 7,346,000  8,051,000 6,942,000 8,145,000                                                   
      total assets
    3,493,437,000 3,679,814,000 3,465,387,000 3,963,173,000 3,599,934,000 3,424,257,000 3,224,385,000 3,264,576,000 3,109,707,000 3,125,890,000 3,059,786,000 3,128,366,000 3,156,149,000 2,996,853,000 3,056,154,000 3,147,974,000 2,662,218,000 2,759,073,000 2,765,233,000 2,984,718,000 2,780,664,000 2,883,043,000 2,947,388,000 1,822,822,000 1,702,470,000 1,747,753,000 1,963,895,000 1,642,075,000 1,182,906,000 1,247,160,000 1,300,283,000 1,307,964,000 800,281,000 450,139,000 511,533,000 424,104,000 487,310,000 204,068,000 213,364,000 273,782,000 184,751,000 231,710,000 242,708,000 295,033,000 319,058,000 337,309,000 275,389,000 291,569,000 304,479,000 183,633,000 193,340,000 204,993,000 53,082,000 42,101,000 46,647,000 54,368,000 61,083,000 74,933,000 47,031,000 45,976,000 50,860,000 48,667,000 52,825,000  65,123,000 32,617,000 37,017,000 25,535,828 29,514,946 32,578,172 35,479,866 38,637,930 26,864,835 31,208,514 35,307,047 46,542,091 52,384,016 58,119,048 56,407,982 39,516,477 40,542,949 45,698,213 28,518,631 32,373,194 38,142,082 28,603,757 33,815,113 39,372,503 30,456,128 
      liabilities and stockholders’ equity
                                                                                             
      current liabilities:
                                                                                             
      accounts payable
    94,015,000 136,702,000 156,105,000 214,442,000 118,774,000 107,417,000 91,536,000 164,918,000 87,948,000 109,796,000 106,710,000 95,875,000 118,461,000 56,207,000 54,007,000 76,741,000 44,163,000 76,681,000 76,651,000 111,090,000 74,528,000 91,660,000 26,595,000 68,094,000 81,946,000 44,045,000 26,499,000 33,829,000 20,408,000 17,382,000 17,379,000 8,467,000 5,317,000 10,921,000 27,446,000 29,690,000 20,684,000 17,133,000 18,673,000 20,234,000 7,431,000 14,095,000 9,318,000 12,408,000 967,000 1,309,000 7,721,000 17,634,000 8,129,000 6,727,000 7,073,000 7,532,000 4,334,000 8,813,000 8,195,000 9,396,000 7,899,000 10,975,000 6,484,000 1,311,000 4,945,000 2,369,000 1,761,000  4,303,000 1,506,000 1,279,000 2,014,130 3,258,153 2,325,242 3,367,551 3,026,072 5,274,320 2,348,603 1,889,929 1,155,961 1,288,154 1,250,512 1,861,604 1,641,261 1,256,438 1,574,051 1,456,196 737,067 1,608,139 4,540,745 2,772,434 1,245,126 1,217,702 
      accrued expenses
    295,793,000 377,399,000 391,650,000 373,513,000 344,830,000 350,404,000 283,317,000 314,997,000 322,350,000 326,877,000 345,554,000 418,996,000 368,998,000 383,699,000 293,908,000 271,697,000 221,009,000 240,141,000 180,636,000 193,553,000 199,063,000 159,088,000 176,298,000 185,527,000 121,663,000 107,328,000 100,120,000 134,095,000 88,687,000 72,477,000 65,648,000 68,982,000 55,752,000 39,179,000 31,157,000 31,016,000 29,539,000 35,064,000 24,277,000 29,053,000 19,761,000 15,184,000 15,039,000 17,366,000 14,824,000 13,839,000 16,340,000                                           
      deferred revenue, current portion
    485,449,000 395,431,000 44,859,000 130,256,000 127,001,000 122,036,000 112,000,000 50,416,000 22,494,000 44,989,000 67,239,000 89,244,000 89,244,000 89,244,000 89,244,000 89,244,000 89,244,000 89,244,000 89,244,000 89,244,000 89,244,000 89,311,000 91,073,000                                                                   
      contingent consideration, current portion
    36,000,000                                                                                         
      other current liabilities
    10,168,000 10,416,000 12,974,000 13,473,000 17,289,000 17,128,000 16,270,000  17,951,000 16,992,000 17,381,000 15,489,000 26,213,000 16,416,000 17,803,000 15,051,000 19,027,000 18,956,000 18,205,000 22,139,000 15,553,000 14,837,000 12,463,000 11,146,000 8,944,000 7,413,000 6,762,000 2,463,000 1,995,000 2,011,000 4,723,000 1,392,000 1,366,000 1,340,000 1,377,000 1,305,000 1,300,000 1,324,000 1,303,000 1,275,000 1,283,000 1,372,000      888,000 15,000 15,000                                        
      total current liabilities
    921,425,000 919,948,000 605,588,000 731,684,000 699,489,000 688,490,000 608,709,000 653,659,000 450,743,000 498,654,000 536,884,000 619,604,000 602,916,000 545,566,000 454,962,000 452,733,000 373,443,000 425,022,000 364,736,000 416,026,000 378,388,000 354,896,000 306,429,000 264,767,000 215,856,000 162,089,000 137,366,000 173,690,000 114,393,000 104,687,000 91,196,000 88,332,000 70,470,000 65,960,000 74,629,000 75,422,000 64,933,000 66,930,000 55,160,000 62,294,000 37,667,000 38,962,000 33,906,000 36,867,000 22,726,000 29,404,000 37,758,000 35,966,000 51,101,000 92,433,000 103,659,000 78,886,000 55,200,000 17,131,000 29,923,000 20,601,000 26,531,000 36,938,000 43,220,000 45,857,000 43,765,000 37,268,000 26,341,000  43,059,000 26,288,000 11,616,000 7,287,576 10,666,058 8,826,906 12,141,612 9,752,329 9,550,330 4,886,894 4,346,755 2,182,879 2,264,821 2,209,804 2,747,973 2,522,589 1,926,660 2,277,914 2,249,598 1,349,437 2,166,913 5,122,134 3,281,066 1,614,158 1,617,801 
      long-term debt
    1,035,146,000 1,139,458,000 1,138,289,000 1,137,124,000 1,135,965,000 1,134,810,000 1,133,660,000 1,132,515,000 1,236,755,000 1,235,517,000 1,234,284,000 1,544,292,000 1,542,770,000 1,100,873,000 1,098,847,000 1,096,876,000 1,094,912,000 1,092,985,000 1,091,110,000 992,493,000 700,470,000 694,156,000 687,953,000 681,900,000 436,421,000 431,040,000 425,752,000 420,554,000 415,446,000 429,925,000 427,365,000 424,876,000 26,550,000  2,343,000 6,042,000 8,491,000 10,111,000 13,373,000 14,969,000 17,397,000 20,652,000 1,450,000 1,476,000 1,501,000 1,525,000 1,551,000 1,576,000 1,599,000  1,645,000                                       
      lease liabilities, net of current portion
    215,042,000 214,419,000 205,460,000 192,473,000 170,009,000 143,601,000 140,102,000 140,965,000 134,752,000 129,170,000 53,931,000 57,578,000 35,229,000 39,368,000 38,620,000 41,512,000 63,428,000 65,285,000 60,675,000 80,367,000                                                                      
      deferred revenue, net of current portion
      325,000,000 325,000,000 325,000,000 325,000,000 325,000,000 437,000,000 485,000,000 485,000,000 485,000,000 485,000,000 507,494,000 529,989,000 552,239,000 574,244,000 596,738,000 619,233,000 641,483,000 663,488,000 685,982,000 708,476,000 732,667,000                                                                   
      contingent consideration, net of current portion
    300,000                                                                                         
      other non-current liabilities
    1,404,000 1,204,000 927,000 1,750,000 1,000,000 7,087,000 7,522,000 3,000,000  38,000 38,000 42,000  11,000,000 11,000,000 11,000,000 20,569,000 20,640,000 20,984,000 19,785,000 5,048,000 10,248,000 10,248,000 10,248,000                                                                  
      total liabilities
    2,173,317,000 2,322,429,000 2,322,664,000 2,435,431,000 2,378,863,000 2,347,188,000 2,263,193,000 2,405,239,000 2,345,350,000 2,384,479,000 2,347,037,000 2,743,416,000 2,725,309,000 2,270,396,000 2,199,268,000 2,219,965,000 2,192,690,000 2,273,965,000 2,229,788,000 2,222,959,000 1,888,617,000 1,840,177,000 1,802,560,000 1,004,635,000 707,266,000 648,586,000 615,331,000 609,799,000 543,058,000 548,113,000 523,523,000 518,747,000 103,125,000 72,367,000 82,391,000 87,413,000 78,686,000 82,608,000 74,402,000 83,435,000 61,515,000 66,334,000 41,949,000 47,380,000 32,854,000 37,388,000 46,427,000 44,377,000 57,495,000 94,812,000 106,059,000                                       
      commitments and contingencies
                                                                                            
      stockholders’ equity:
                                                                                             
      preferred stock, 0.0001 par value, 3,333,333 shares authorized; none issued and outstanding
                                                                                             
      common stock
    11,000 10,000 10,000 10,000 10,000 10,000 9,000 9,000 9,000 9,000 9,000 9,000 9,000 9,000 9,000 9,000 8,000 8,000 8,000 8,000 8,000 8,000 8,000 8,000 7,000 7,000 7,000 7,000 7,000 7,000 7,000 6,000 6,000 6,000 5,000 5,000 5,000 5,000 5,000 5,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 3,000 3,000 3,000 2,000 2,000 13,000 13,000 13,000 14,000 11,000 11,000 11,000 11,000 11,000  11,000 9,000 9,000 7,110 7,116 7,109 7,043 6,445 5,373 5,365 5,328 5,297 5,296 5,293 5,118 4,418 4,418 4,415 3,614 3,612 3,612 2,656 2,322 2,307 2,153 
      treasury stock
    -25,263,000 -25,263,000                                                                                        
      additional paid-in capital
    5,986,689,000 5,844,279,000 5,801,161,000 5,738,924,000 5,588,839,000 5,481,723,000 5,371,968,000 5,304,623,000 5,256,854,000 5,193,388,000 5,140,150,000 4,296,841,000 4,235,028,000 4,272,187,000 4,168,956,000 4,134,768,000 3,554,307,000 3,521,721,000 3,490,658,000 3,609,877,000 3,550,857,000 3,505,165,000 3,455,689,000 3,112,130,000 3,053,420,000 3,031,050,000 3,004,107,000 2,611,294,000 2,077,864,000 2,061,039,000 2,029,767,000 2,006,598,000 1,890,172,000 1,523,080,000 1,511,422,000 1,503,126,000 1,486,487,000 1,142,580,000 1,097,787,000 1,089,508,000 957,607,000 947,826,000 941,356,000 926,769,000 920,864,000 905,335,000 800,526,000 790,424,000 781,396,000 581,204,000 560,613,000 554,927,000 364,616,000 342,128,000 341,677,000 340,968,000 340,293,000 339,669,000 306,722,000 304,818,000 304,154,000 301,139,000 299,515,000  298,487,000 274,684,000 274,118,000 266,034,912 265,501,292 264,358,554 262,151,126 252,732,858 237,450,696 246,190,431 244,382,818 239,726,657 238,708,122 237,598,487 226,290,167 205,086,142 205,016,072 204,887,443 182,370,440 182,297,550 182,271,542 139,327,069 116,711,776 116,075,119 105,587,511 
      accumulated other comprehensive income, net of tax
    220,000  34,000 -218,000 2,245,000 -1,030,000 -691,000 918,000        -20,000 -20,000 2,000 -3,000 3,000 -6,000 6,000 624,000 50,000                                                                  
      accumulated deficit
    -4,641,537,000 -4,461,590,000 -4,658,482,000 -4,210,974,000 -4,370,023,000 -4,403,634,000 -4,410,094,000 -4,446,213,000 -4,491,868,000 -4,450,931,000 -4,426,991,000 -3,910,236,000 -3,800,992,000 -3,543,254,000 -3,311,773,000 -3,206,748,000 -3,084,767,000 -3,036,623,000 -2,955,218,000 -2,848,129,000 -2,658,812,000 -2,462,313,000 -2,311,493,000 -2,294,001,000 -2,058,298,000 -1,931,972,000 -1,655,569,000 -1,578,926,000 -1,438,031,000 -1,361,638,000 -1,252,371,000 -1,217,008,000 -1,193,010,000 -1,145,276,000 -1,082,230,000 -1,166,320,000 -1,077,868,000 -1,021,126,000 -958,825,000 -899,055,000 -834,374,000 -782,435,000 -740,584,000 -679,025,000 -634,609,000 -605,383,000                                            
      total stockholders’ equity
    1,320,120,000 1,357,385,000 1,142,723,000 1,527,742,000 1,221,071,000 1,077,069,000 961,192,000 859,337,000 764,357,000 741,411,000 712,749,000 384,950,000 430,840,000 726,457,000 856,886,000 928,009,000 469,528,000 485,108,000 535,445,000 761,759,000 892,047,000 1,042,866,000 1,144,828,000 818,187,000 995,204,000 1,099,167,000 1,348,564,000 1,032,276,000 639,848,000 699,047,000 776,760,000 789,217,000 697,156,000 377,772,000 429,142,000 336,691,000 408,624,000 121,460,000 138,962,000 190,347,000 123,236,000 165,376,000 200,759,000 247,653,000 286,204,000 299,921,000 228,962,000 247,192,000 246,984,000 88,821,000                                        
      total liabilities and stockholders’ equity
    3,493,437,000 3,679,814,000 3,465,387,000 3,963,173,000 3,599,934,000 3,424,257,000 3,224,385,000 3,264,576,000 3,109,707,000 3,125,890,000 3,059,786,000 3,128,366,000 3,156,149,000 2,996,853,000 3,056,154,000 3,147,974,000 2,662,218,000 2,759,073,000 2,765,233,000 2,984,718,000 2,780,664,000 2,883,043,000 2,947,388,000 1,822,822,000 1,702,470,000 1,747,753,000 1,963,895,000 1,642,075,000 1,182,906,000 1,247,160,000 1,300,283,000 1,307,964,000 800,281,000 450,139,000 511,533,000 424,104,000 487,310,000 204,068,000 213,364,000 273,782,000 184,751,000 231,710,000 242,708,000 295,033,000 319,058,000 337,309,000 275,389,000 291,569,000 304,479,000 183,633,000                                        
      strategic investments
     195,522,000 154,370,000                                                                                       
      contingent consideration
     47,400,000 47,400,000 47,400,000 47,400,000 48,200,000 48,200,000 38,100,000 38,100,000 36,100,000 36,900,000 36,900,000 36,900,000 43,600,000 43,600,000 43,600,000 43,600,000 50,800,000 50,800,000 50,800,000 50,500,000                                                                     
      accumulated other comprehensive loss, net of tax
     -51,000       -638,000 -1,055,000 -419,000 -1,664,000 -3,205,000 -2,485,000 -306,000                                                                           
      current portion of long-term debt
        91,595,000 91,505,000 105,586,000 105,483,000                      9,514,000 3,446,000 6,175,000 4,732,000 11,217,000 11,346,000 10,108,000 10,107,000 10,106,000 7,604,000 5,936,000 3,435,000 100,000 99,000 98,000 97,000 96,000 94,000 92,000 91,000                                         
      current portion of lease liabilities
           17,845,000                                                                                  
      intangible assets
               7,578,000 13,057,000 13,062,000 13,328,000 14,239,000 14,204,000 14,105,000 14,124,000 13,628,000 13,344,000 13,105,000 12,813,000 12,497,000                                                                  
      preferred stock, .0001 par value, 3,333,333 shares authorized; none issued and outstanding
                                                                                           
      lease liabilities
                        68,229,000 72,401,000 65,263,000 47,720,000 49,741,000 50,209,000 52,165,000                                                               
      intangible assets, net of accumulated amortization of 5,091 and 3,852 as of september 30, 2019, and december 31, 2018, respectively
                            11,975,000                                                                 
      right of use asset
                            39,493,000 39,449,000                                                                
      other assets
                            169,171,000 151,860,000 133,313,000  78,664,000 35,435,000 12,466,000     3,967,000    4,470,000 7,670,000 5,313,000 5,275,000 2,063,000 5,729,000 6,441,000 25,000 25,000 25,000 1,625,000 1,525,000 2,775,000 2,425,000 231,000 206,000 155,000 139,000 123,000 386,000 123,000 111,000 111,000 111,000  121,000 78,000 35,000 34,709 34,709 34,709 34,709 34,709 34,709 34,709 284,709 34,709 34,709 34,709 37,609 37,609 37,609 37,609 37,609 34,709 34,709 29,847 29,847 29,847 29,847 
      deferred revenue
                            3,303,000 3,303,000 3,985,000 3,303,000 3,303,000 3,303,000  3,316,000 3,303,000 3,303,000 3,303,000 3,303,000 3,303,000 3,303,000 3,303,000 3,303,000 3,303,000 3,303,000 3,363,000 3,318,000 3,362,000 3,303,000 3,303,000 3,299,000 3,963,000 4,499,000 3,884,000 3,304,000 3,304,000 3,304,000 3,304,000 3,304,000 3,304,000 3,304,000 3,304,000 3,304,000 3,335,000 3,366,000 3,409,000  2,096,000 2,128,000 2,159,000 2,190,000 2,243,750 2,275,000 1,596,250 737,500                  
      deferred rent and other
                            5,248,000 5,248,000 48,000 15,555,000 13,219,000 13,501,000 4,962,000 5,539,000 6,105,000 6,407,000 5,419,000 5,949,000 5,262,000 5,567,000 5,869,000 6,172,000 6,451,000 6,720,000                                                
      accumulated other comprehensive income
                            75,000 82,000 19,000  8,000         1,000                                     16,377 19,327 17,200 14,858 12,968       729,956 1,038,956  -13,278,794 
      intangible assets, net of accumulated amortization of 4,685 and 3,852 as of june 30, 2019, and december 31, 2018, respectively
                             11,825,000                                                                
      intangible assets, net of accumulated amortization of 4,276 and 3,852 as of march 31, 2019, and december 31, 2018, respectively
                              11,781,000                                                               
      right of use asset, net of accumulated amortization of 1,491 and nil as of march 31, 2019 and december 31, 2018, respectively
                              41,098,000                                                               
      intangible assets, net of accumulated amortization of 3,852 and 4,145 as of december 31, 2018 and 2017, respectively
                               11,574,000                                                              
      investments and other assets
                               107,294,000    21,809,000                                                          
      accumulated other comprehensive loss
                               -99,000  -361,000 -643,000 -379,000 -12,000 -38,000 -55,000 -120,000   -5,000 -111,000 -1,000  -17,000 -95,000 -55,000 -35,000 -59,000                                           
      intangible assets, net of accumulated amortization of 5,532 and 4,145 as of september 30, 2018, and december 31, 2017, respectively
                                15,324,000                                                             
      intangible assets, net of accumulated amortization of 5,100 and 4,145 as of june 30, 2018 and december 31, 2017, respectively
                                 14,857,000                                                            
      intangible assets, net of accumulated amortization of 4,659 and 4,145 as of march 31, 2018 and december 31, 2017, respectively
                                  14,473,000                                                           
      restricted investment
                                       10,695,000 10,695,000 10,695,000 10,695,000 10,695,000                                                  
      intangible assets, net of accumulated amortization of 4,145 and 3,134 as of december 31, 2017 and 2016, respectively
                                   14,355,000                                                          
      asset held for sale
                                    1,501,000 1,529,000 1,529,000                                                       
      restricted cash and investments
                                    784,000 784,000 784,000 784,000 784,000 783,000 783,000 783,000 11,478,000 783,000 783,000 782,000                                              
      intangible assets, net of accumulated amortization of 3,762 and 3,134 as of september 30, 2017 and december 31, 2016, respectively
                                    14,029,000                                                         
      intangible assets, net of accumulated amortization of 2,862 and 3,134 as of june 30, 2017 and december 31, 2016, respectively
                                     7,795,000                                                        
      intangible assets, net of accumulated amortization of 2,758 and 3,134 as of march 31, 2017 and december 31, 2016, respectively
                                      7,684,000                                                       
      intangible assets, net of accumulated amortization of 3,134 and 2,620 as of december 31, 2016 and 2015, respectively
                                       8,076,000                                                      
      current portion of notes payable
                                           2,493,000 2,454,000 4,908,000 4,831,000 2,492,000 2,415,000                                             
      intangible assets, net of accumulated amortization of 3,054 and 2,620 as of september 30, 2016 and december 31, 2015, respectively
                                        8,111,000                                                     
      patent costs, net of accumulated amortization of 2,903 and 2,620 as of june 30, 2016 and december 31, 2015, respectively
                                         6,991,000                                                    
      patent costs, net of accumulated amortization of 2,774 and 2,620 as of march 31, 2016 and december 31, 2015, respectively
                                          6,728,000                                                   
      patent costs, net of accumulated amortization of 2,620 and 2,081 as of december 31, 2015 and 2014, respectively
                                           6,642,000                                                  
      notes payable
                                               2,262,000 2,262,000                                             
      patent costs, net of accumulated amortization of 2,486 and 2,081 as of september 30, 2015 and december 31, 2014, respectively
                                            6,116,000                                                 
      patent costs, net of accumulated amortization of 2,353 and 2,081 as of june 30, 2015 and december 31, 2014, respectively
                                             6,024,000                                                
      unrealized loss
                                             -19,000                                                
      patent costs, net of accumulated amortization of 2,216 and 2,081 as of march 31, 2015 and december 31, 2014, respectively
                                              5,842,000                                               
      other liabilities
                                              1,256,000 1,185,000 1,061,000 1,031,000 1,087,000    15,000 27,000 85,000 107,000 114,000 126,000 105,000 85,000 69,000 35,000 64,000 77,000 98,000  86,000 217,000 324,000 450,160 435,086 143,835 237,585 331,335 1,238,152 1,336,821 1,435,490 346,037 314,167 237,904            
      deferred rent
                                              6,593,000 6,775,000 6,365,000                                             
      restricted investments
                                                4,000,000 4,000,000 7,250,000 7,250,000 7,250,000 7,250,000 7,250,000                                       
      patent costs, net of accumulated amortization of 2,081 and 1,622 as of december 31, 2014 and 2013, respectively
                                               5,891,000                                              
      warrant liability
                                                 9,826,000 9,213,000 9,006,000 35,994,000 79,116,000 91,077,000               21,387,000 6,815,000 1,253,580 2,970,857 2,801,882 5,849,341 4,414,657 1,642,246                 
      patent costs, net of accumulated amortization of 1,972 and 1,622 as of september 30, 2014 and december 31, 2013, respectively
                                                5,689,000                                             
      patent costs, net of accumulated amortization of 1,853 and 1,622 as of june 30, 2014 and december 31, 2013, respectively
                                                 5,387,000                                            
      deferred rent and other long-term liabilities
                                                 6,459,000 7,118,000 6,835,000                                          
      patent costs, net of accumulated amortization of 1,740 and 1,622
                                                  5,217,000                                           
      deficit accumulated during the development stage
                                                  -571,509,000 -543,236,000 -534,416,000 -492,386,000 -473,335,000 -431,251,000 -369,184,000 -319,630,000 -327,668,000 -309,964,000 -308,554,000 -304,534,000 -305,813,000 -307,646,000                             -63,472,543 
      patent costs, net of accumulated amortization of 1,622 and 2,626
                                                   5,042,000                                          
      accrued employee compensation
                                                   5,047,000 2,909,000 1,986,000 1,520,000 2,741,000 2,180,000 1,936,000 1,852,000 2,244,000 2,250,000 2,551,000 2,088,000 2,015,000 2,223,000 1,837,000 495,000  1,098,000 974,000 964,000 1,305,829 1,684,540 1,208,143 1,064,891 1,171,666 1,325,351 1,132,036 1,021,336 680,881 662,500 721,388 886,369  670,222 703,863 793,402 612,370 558,774 581,389 508,632 369,032 400,099 
      patent costs, net of accumulated amortization of 1,538 and 2,626
                                                    5,231,000                                         
      other long-term liabilities
                                                    4,795,000 757,000 755,000 760,000 758,000 757,000 967,000 993,000 1,022,000 1,046,000 1,070,000 1,094,000 1,069,000 1,075,000 1,108,000  610,000 579,000 530,000 515,621 495,002 474,385 453,767 433,149                  
      patent costs, net of accumulated amortization of 1,439 and 2,626
                                                     5,186,000                                        
      long-term debt, current portion
                                                     90,000 90,000 89,000 88,000 87,000 86,000 85,000 84,000 83,000 82,000 81,000 80,000 79,000 78,000  76,000 76,000 75,000 73,877 73,672 72,804 25,994 71,099 70,261 69,434                
      long-term debt, non-current portion
                                                     1,622,000  1,668,000 1,690,000 1,713,000 1,735,000 1,757,000 1,778,000 1,800,000 1,821,000 1,842,000 1,863,000 1,883,000 1,903,000  1,950,000 1,962,000 1,981,000 2,000,789 2,015,124 2,033,871 2,098,349 2,070,704 2,088,797 2,106,675                
      patent costs, net of accumulated amortization of 1,534 and 2,626
                                                      4,883,000                                       
      liabilities and shareholders’ equity
                                                                                             
      shareholders’ equity:
                                                                                             
      total shareholders’ equity
                                                      87,281,000 123,679,000 -4,566,000 22,500,000 14,022,000  31,752,000 35,149,000 920,000 -2,817,000 4,163,000 8,441,000   19,504,000 3,788,000 22,890,000 15,731,842 16,338,762 21,243,010 20,786,138 26,381,748 15,225,708 24,214,945 30,960,292 44,359,212 50,119,195 55,909,244 53,660,009 36,993,888 38,616,289 43,420,299 26,269,033 31,023,757 35,975,169     
      total liabilities and shareholders’ equity
                                                      193,340,000 204,993,000 53,082,000 42,101,000 46,647,000  61,083,000 74,933,000 47,031,000 45,976,000 50,860,000 48,667,000   65,123,000 32,617,000 37,017,000 25,535,828 29,514,946 32,578,172 35,479,866 38,637,930 26,864,835 31,208,514 35,307,047 46,542,091 52,384,016 58,119,048 56,407,982 39,516,477 40,542,949 45,698,213 28,518,631 32,373,194 38,142,082     
      patent costs, net of accumulated amortization of 2,626 and 2,199
                                                       4,913,000                                      
      warrant valuation
                                                       65,193,000 45,209,000 2,884,000 16,372,000 5,446,000 12,889,000 19,940,000 31,193,000 39,111,000 33,118,000 29,540,000 20,500,000  35,400,000                         
      patent costs, net of accumulated amortization of 2,521 and 2,199
                                                        4,837,000                                     
      patent costs, net of accumulated amortization of 2,413 and 2,199
                                                         4,740,000                                    
      patent costs, net of accumulated amortization of 2,298 and 2,199
                                                          4,704,000                                   
      preferred stock, .0001 par value, 20,000,000 shares authorized; none issued and outstanding
                                                                                            
      property held for sale
                                                            1,856,000 1,965,000 1,965,000 1,965,000 1,979,000 2,372,000 2,372,000                           
      patent costs, net of accumulated amortization of 2,199 and 1,742
                                                           4,764,000                                  
      liabilities and shareholders' equity
                                                                                             
      shareholders' equity
                                                                                             
      total shareholders' equity
                                                           31,017,000       23,473,000                       23,481,623 30,534,047 37,758,345 28,838,327 
      total liabilities and shareholders' equity
                                                           54,368,000       52,825,000                       28,603,757 33,815,113 39,372,503 30,456,128 
      patent costs, net of accumulated amortization of 1,901 and 1,742
                                                            4,698,000                                 
      shareholders’ equity
                                                                                             
      patent costs, net of accumulated amortization of 1,845 and 1,742
                                                             4,459,000                                
      patent costs, net of accumulated amortization of 1,790 and 1,742
                                                              4,074,000                               
      patent costs, net of accumulated amortization of 1,742 and 1,762
                                                               3,980,000                              
      patent costs, net of accumulated amortization of 1,870 and 1,762
                                                                4,301,000                             
      patent costs, net of accumulated amortization of 1,829 and 1,762
                                                                 4,068,000                            
      short-term securities —available-for-sale
                                                                  172,000                           
      patent costs, net of accumulated amortization of 1,787 and 1,762
                                                                  3,832,000                           
      shareholders' equity:
                                                                                             
      operating leases
                                                                   2,387,000                          
      royalty payments
                                                                   250,000                          
      report of kpmg llp, independent registered public accounting firm
                                                                                             
      report of arthur andersen, independent auditors
                                                                                             
      balance sheets
                                                                                             
      statements of operations
                                                                                             
      statements of shareholders’ equity and comprehensive income
                                                                                             
      statements of cash flows
                                                                                             
      notes to financial statements
                                                                                             
      short-term securities—available-for-sale
                                                                    169,000 168,000 285,000 282,062 279,528 276,618 274,209 271,851 10,188,487 10,056,789 12,081,196 12,846,772 12,709,104  12,453,348 3,400,631 4,840,163 2,834,650 2,860,487  18,129,230 8,908,682  6,596,477 4,618,206 
      patent costs, net of accumulated amortization of 1,959 and 1,927
                                                                    3,580,000  3,269,000                       
      assets held for sale
                                                                    2,373,000                         
      patent costs, net of accumulated amortization of 1,891 and 1,927
                                                                     3,452,000                        
      accumulated other comprehensive income deficit accumulated during the development stage
                                                                                             
      patent costs, net of accumulated amortization of 1,926,941 and 1,725,074
                                                                       3,267,778                      
      patent costs, net of accumulated amortization of 1,858,214 and 1,725,074
                                                                        3,542,520                     
      patent costs, net of accumulated amortization of 1,813,214 and 1,725,074
                                                                         3,522,911                    
      patent costs, net of accumulated amortization of 1,766,674 and 1,725,074
                                                                          3,404,340                   
      patent costs, net of accumulated amortization of 1,725,074 and 1,496,699
                                                                           3,066,625                  
      patent costs, net of accumulated amortization of 1,674,130 and 1,496,699
                                                                            2,976,692                 
      patent costs, net of accumulated amortization of 1,580,130 and 1,496,699
                                                                             2,769,042                
      patent costs, net of accumulated amortization of 1,533,630 and 1,496,699
                                                                              2,611,476               
      patent costs, net of accumulated amortization of 1,435,381 and 1,270,881
                                                                               2,472,389              
      patent costs, net of accumulated amortization of 1,373,381 and 1,270,881
                                                                                2,312,323             
      short-term securities–available-for-sale
                                                                                 12,579,208         14,527,670   
      patent costs, net of accumulated amortization of 1,320,381 and 1,270,881
                                                                                 2,163,209            
      patent costs, net of accumulated amortization of 1,270,881 and 1,061,788
                                                                                  2,117,710           
      patent costs, net of accumulated amortization of 1,216,288 and 1,061,788
                                                                                   2,091,142          
      accrued employee compensation and deferred revenue
                                                                                   881,328          
      patent costs, net of accumulated amortization of 1,161,788 and 1,061,788
                                                                                    2,066,631         
      patent costs, net of accumulated amortization of 1,109,788 and 1,061,788
                                                                                     2,042,217        
      patent costs, net of accumulated amortization of 1,061,788 and 877,038
                                                                                      1,968,987       
      short-term securities-available-for-sale
                                                                                       10,762,976      
      patent costs, net of accumulated amortization of 1,010,038 and 877,038
                                                                                       1,946,660      
      patent costs, net of accumulated amortization of 964,038 and 877,038
                                                                                        1,893,643     
      related party receivables
                                                                                         513,250 1,715,032   
      patent costs, net of accumulated amortization of 727,901 and 694,193
                                                                                         1,587,632    
      patent costs, net of accumulated amortization of 694,193 and 541,185
                                                                                          1,376,402   
      preferred stock, .0001 par value, 2,000,000 shares authorized; none issued and outstanding
                                                                                             
      patent costs, net of accumulated amortization of 606,185 and 541,185
                                                                                           1,058,738  
      patent costs, net of accumulated amortization of 571,185 and 541,185
                                                                                            954,764 
    The information provided in this report is taken from www.sec.gov and many other data providers. While we have conducted our best efforts to ensure that the parsed data is accurate, we cannot guarantee its accuracy. Please use caution and understand that any consequences of its use are your own responsibility.