7Baggers
Quarterly
Annual
    Unit: USD2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 
      
                                               
      cash flows from operating activities
                                               
      net income
    -62,214,000 -95,778,000 -93,551,000 -102,854,000 -108,483,000 -32,706,000 -201,630,000 -160,325,000 -146,828,000 -147,146,000 -137,323,000 -126,260,000 -122,055,000 -124,712,000 -130,171,000 -107,245,000 -95,764,000 974,895,000 -105,735,000 -136,347,000 -126,740,000 -168,653,000 -179,958,000 -168,221,000 -163,406,000 -158,388,000 -122,918,000 -16,978,000 -74,598,000 -69,422,000 -73,719,000 -70,201,000 -56,778,000 -55,901,000 -37,796,000 -34,747,000 -30,543,000 -28,562,000 -24,035,000 -25,027,000 -16,871,000 -12,361,000 -9,468,000 
      adjustments to reconcile net income to net cash from operating activities:
                                               
      stock-based compensation expense
    6,927,000 9,432,000 14,207,000 17,167,000 13,698,000 12,945,000 28,691,000 11,693,000 20,038,000 15,244,000 13,169,000 14,636,000 18,553,000 20,648,000 34,342,000 27,663,000 21,976,000 20,744,000 20,108,000 24,032,000 31,110,000 30,679,000 43,669,000 34,767,000 44,116,000 31,640,000 25,478,000 29,028,000 15,817,000 10,245,000 9,731,000 9,350,000 6,208,000 10,093,000 4,748,000 4,465,000 3,714,000 4,086,000 4,407,000 5,398,000 1,349,000 1,326,000 691,000 
      premium on marketable securities
    -137,000 -158,000 -51,000 -112,000 -23,000 -61,000 -42,000 -29,000 -36,000 -10,000 -265,000 -1,189,000 -3,849,000 -2,919,000 -7,414,000 -9,459,000 -670,000 -572,000 -254,000 -240,000 -1,022,000 -765,000 -1,148,000 -739,000 -50,000 -90,000 -71,000 -4,000 -56,000    -93,000 -394,000         
      amortization of discount on marketable securities
    -981,000  -2,047,000 -1,937,000 -1,554,000                -18,000 -537,000 -1,456,000 -2,651,000 -2,322,000                   
      depreciation expense
    112,000 129,000 255,000 311,000 336,000 409,000 330,000 331,000 323,000 290,000 278,000                                 
      changes in operating assets and liabilities:
                                               
      prepaid expenses and other current assets
    -2,144,000 1,881,000 9,113,000 -2,155,000 5,237,000 2,880,000 11,616,000 12,529,000 -8,024,000 2,191,000 -11,562,000 -4,249,000 2,635,000 -5,498,000 -5,497,000 -5,763,000 -262,000 7,526,000 -1,485,000 -3,383,000 1,221,000 3,713,000 -3,392,000 -6,739,000 1,637,000 -3,191,000 12,820,000 -19,743,000 -5,348,000 -1,335,000 301,000 1,287,000 -1,380,000 -1,682,000 -1,606,000 1,115,000 -1,189,000 867,000 671,000 -2,085,000 -134,000 7,000 -287,000 
      collaboration receivable - related party
    -1,595,000 5,737,000 -4,928,000 566,000 72,500,000 -60,496,000 -7,423,000 -88,000 -1,342,000 4,788,000 5,274,000 -3,925,000 -1,291,000 5,679,000 24,253,000 -23,672,000 -24,766,000                           
      other long-term assets
    220,000 847,000 2,625,000 -84,000 332,000 45,000 296,000 -2,634,000 515,000 139,000 -2,000 -316,000 -340,000 -376,000 -276,000 -207,000 -51,000 86,000 -12,000 279,000 99,000 25,000 205,000 -2,645,000 -1,378,000                   
      right-of-use operating asset
    396,000 623,000 1,441,000 1,637,000 1,601,000 1,568,000 1,534,000 1,502,000 1,470,000 1,438,000 1,409,000 1,380,000 1,350,000 1,323,000 1,296,000 1,269,000 1,333,000 1,483,000 1,453,000 1,683,000 1,778,000 1,744,000                      
      operating lease liabilities, current
    494,000 1,235,000 -1,328,000 -1,895,000 -1,859,000 -1,802,000 -758,000 41,000 41,000 40,000 40,000 40,000 55,000 54,000 55,000 53,000 44,000 42,000 43,000 -74,000 25,000                       
      operating lease liabilities, non-current
    -475,000 -1,228,000    -1,003,000 -1,760,000 -1,728,000 -1,673,000 -1,636,000 -1,596,000 -1,568,000 -1,517,000 -1,482,000 -1,447,000 -1,498,000 -1,631,000 -1,592,000 -1,705,000 -1,897,000                       
      accounts payable
    -7,264,000 5,573,000 -1,524,000 2,171,000 -3,839,000 -818,000 1,889,000 -3,016,000 -6,550,000 11,790,000 1,868,000 -1,974,000 -3,251,000 5,647,000 1,816,000 -368,000 -406,000 -598,000 1,902,000 -5,508,000 -7,307,000 10,172,000 -7,149,000 -1,299,000 -20,507,000 27,914,000 -2,467,000 -26,000 -877,000 -3,914,000 6,989,000 -2,125,000 -4,643,000 7,680,000 -825,000 1,740,000 -799,000 1,882,000 -1,952,000 2,417,000 343,000 447,000 379,000 
      accrued expenses and other liabilities
    -15,067,000 6,090,000 -6,726,000 6,748,000 -15,778,000 -47,664,000 35,543,000 14,642,000 -8,389,000 -12,668,000 8,562,000 13,230,000 -4,507,000 443,000 5,349,000 10,106,000 -4,140,000 8,025,000 -6,100,000 1,309,000 -35,391,000 8,312,000 19,522,000 14,162,000 -8,192,000 2,925,000 9,450,000 10,215,000 -12,460,000 5,684,000 10,581,000 2,511,000 1,220,000 5,846,000 4,920,000 937,000 1,341,000 3,743,000      
      net cash from operating activities
    -81,728,000 -66,560,000 -82,365,000 -80,437,000 -37,832,000 -119,519,000 -135,866,000 -131,518,000 -153,682,000 -126,932,000 -118,865,000 -106,439,000 -107,800,000 -97,501,000 -68,826,000 -102,769,000 -109,086,000 1,010,971,000 -91,016,000 -118,984,000 -136,691,000 -116,726,000 -128,702,000 -133,344,000 -149,934,000 -101,778,000 -80,187,000 -135,000 -78,571,000 -58,899,000 -46,092,000 -59,076,000 -55,210,000 -33,776,000 -30,796,000 -26,671,000 -27,435,000 -18,117,000 -19,515,000 -18,443,000 -14,606,000 -8,667,000 -7,486,000 
      capex
    112,000 -328,000 -112,000 -225,000 -199,000 -566,000 -122,000 -169,000 1,000 -70,000 -261,000 -319,000 -2,181,000 -2,007,000 -1,179,000 -776,000 -989,000 -407,000 -637,000 508,000 -235,000 -76,000 -181,000 -520,000 -66,000 -62,000 -38,000 21,000 -71,000 -110,000 -45,000 -78,000 
      free cash flows
    -81,728,000 -66,560,000 -82,365,000 -80,437,000 -37,832,000 -119,407,000 -136,194,000 -131,630,000 -153,907,000 -127,131,000 -119,431,000 -106,561,000 -107,969,000 -97,501,000 -68,826,000 -102,769,000 -109,086,000 1,010,971,000 -91,015,000 -119,054,000 -136,952,000 -117,045,000 -130,883,000 -135,351,000 -151,113,000 -102,554,000 -81,176,000 -542,000 -79,208,000 -58,391,000 -46,327,000 -59,152,000 -55,391,000 -34,296,000 -30,862,000 -26,671,000 -27,497,000 -18,155,000 -19,494,000 -18,514,000 -14,716,000 -8,712,000 -7,564,000 
      cash flows from investing activities
                                               
      proceeds from sales and maturities of marketable securities
    133,756,000 135,278,000 183,371,000 197,932,000 201,054,000 176,905,000 230,779,000 278,470,000 351,982,000 288,591,000 362,716,000 263,561,000 292,539,000 288,863,000 338,273,000 177,969,000 182,970,000 135,410,000 170,570,000 320,572,000 275,197,000 213,430,000 369,188,000 281,389,000 307,263,000 250,625,000 460,672,000 181,500,000 81,960,000 46,789,000 104,000,000 59,683,000 50,753,000           
      purchases of marketable securities
    -87,973,000 -88,704,000 -102,317,000 -198,318,000 -61,618,000 -134,956,000 -70,059,000 -232,765,000 -156,890,000 -198,532,000 -251,400,000 -129,177,000 -301,928,000 -318,752,000 -363,256,000 -466,357,000 -841,786,000 -89,891,000 -157,058,000 -143,120,000 -68,651,000 -230,973,000 -159,469,000 -337,317,000 -580,916,000 -211,399,000 -459,622,000 -419,228,000 -394,109,000 -150,587,000 -59,894,000 -15,014,000 -18,908,000 -140,443,000 -35,653,000         
      net cash from investing activities
    45,783,000 46,574,000 81,054,000 -386,000 139,436,000 42,061,000 160,392,000 45,593,000 194,867,000 89,777,000 110,952,000 134,262,000 -9,558,000 -30,261,000 -24,983,000 -288,388,000 -658,816,000 45,519,000 13,513,000 177,382,000 206,270,000 -17,916,000 207,779,000 -58,109,000 -274,910,000 38,418,000 52,000 -238,130,000 -312,801,000 -104,602,000 43,871,000 44,308,000 31,600,000 -118,463,000 -27,720,000 -84,016,000 -341,000 -38,000 21,000 -71,000 -110,000 -45,000 -78,000 
      cash flows from financing activities
                                               
      proceeds from stock option exercises and employee stock purchase plan issuances
    242,000 -1,000 1,435,000 26,000 1,559,000 2,774,000 855,000 3,301,000 33,000 1,244,000 37,000 1,799,000 419,000 1,816,000 6,861,000 5,623,000 2,171,000 3,545,000 386,000 3,160,000 2,166,000 15,402,000 15,601,000 15,681,000 1,628,000 8,078,000 6,645,000 12,757,000 8,974,000 3,687,000 2,758,000 553,000 678,000 416,000 10,000 302,000       
      payment of employee tax obligations related to vesting of restricted stock units
    -94,000 -1,000 -399,000 -1,000 -2,000 -262,000 -4,000 -8,000 -629,000 -4,000 -15,000   -589,000       -1,483,000 -692,000 -904,000               
      net cash from financing activities
    148,000 -2,000 1,037,000 8,071,000 1,557,000 -262,000 2,770,000 847,000 2,672,000 29,000 1,229,000 13,000 1,799,000 -170,000 1,816,000 6,065,000 5,623,000 419,671,000 3,545,000 386,000 3,160,000 2,166,000 13,919,000 15,343,000 576,196,000 1,628,000 8,078,000 6,540,000 643,112,000 334,820,000 3,687,000 2,758,000 553,000 678,000 189,591,000 10,000 140,703,000 31,000 137,000 129,586,000 112,000 -249,000 95,164,000 
      net increase in cash, cash equivalents and restricted cash
    -35,797,000 -19,988,000 -274,000 -72,752,000 103,161,000    43,857,000     -127,932,000 -91,993,000 -385,092,000 -762,279,000 1,476,161,000 -73,958,000 58,784,000 72,739,000 -132,476,000 92,996,000 -176,110,000 151,352,000   -231,725,000 251,740,000               
      cash, cash equivalents, and restricted cash at beginning of period
    82,471,000                                           
      cash, cash equivalents, and restricted cash at end of period
    46,674,000                                           
      reconciliation of cash, cash equivalents, and restricted cash reported in the consolidated balance sheets
                                               
      cash and cash equivalents
    45,224,000                                           
      restricted cash
    1,450,000                                           
      total cash, cash equivalents, and restricted cash shown in the statement of cash flows
    46,674,000                                           
      amortization of (discount) premium on marketable securities
                                               
      purchases of property and equipment
         112,000 -328,000 -112,000 -225,000 -282,000 -364,000 -122,000 -169,000     1,000 -70,000 -276,000 -373,000 -1,940,000 -2,181,000 -1,257,000 -808,000 -998,000 -402,000 -652,000 -804,000 -235,000 -76,000 -245,000 -520,000 -66,000         
      payments of offering costs
                       -258,000 -70,000 -105,000 -235,000             
      proceeds from public offerings of common stock, net of commissions and underwriting discounts
     1,000                   561,277,000 631,494,000     189,175,000         
      supplemental disclosure of non-cash operating activities
                                               
      right-of-use assets obtained in exchange for new operating lease liabilities
     125,000                                         
      purchases of property and equipment included in accounts payable
             83,000 -202,000          15,000 54,000 -241,000 174,000 78,000 32,000 9,000 -5,000 15,000               
      cash, cash equivalents and restricted cash at beginning of period
      72,324,000 163,969,000 295,502,000 1,662,798,000 129,072,000 193,310,000 307,084,000               
      cash, cash equivalents and restricted cash at end of period
      -274,000 -72,752,000 175,485,000 -77,720,000 27,296,000 -85,078,000 207,826,000 -37,126,000 -6,684,000 27,836,000 179,943,000 -127,932,000 -91,993,000 -385,092,000 900,519,000 1,476,161,000 -73,958,000 58,784,000 201,811,000 -132,476,000 92,996,000 -176,110,000 344,662,000 -61,732,000 -72,057,000 -231,725,000 558,824,000               
      amortization of premium (discount) on marketable securities
         6,181,000 -4,951,000 -4,391,000 -3,179,000        1,325,000 420,000 324,000         -2,806,000 -1,348,000               
      net decrease in cash, cash equivalents and restricted cash
         -77,720,000 27,296,000    -6,684,000 27,836,000 -115,559,000                               
      lease asset de-recognized upon lease cancellation
                 3,733,000                         
      adjustments to reconcile net income to net cash (used in) operating activities:
                                               
      amortization of premium on marketable securities
             -1,329,000 1,068,000 2,581,000 3,533,000  4,034,000                -62,000 -28,000 33,000 199,000 74,000         
      proceeds from the sale of common stock under the stock purchase agreement - related party
                                               
      supplemental disclosure of non-cash operating and investing activities
                                               
      depreciation
                275,000 333,000 374,000 893,000 2,582,000 649,000 650,000 662,000 669,000 665,000 698,000 505,000 415,000 363,000 287,000 246,000 247,000 135,000 136,000 130,000 130,000 82,000 83,000 75,000 41,000 32,000      
      proceeds from the sale of common stock under the stock purchase agreement
                                               
      landlord tenant incentive included in other current assets
                                               
      public offering costs included in accounts payable
                                               
      purchases of property and equipment financed with landlord tenant incentive
                                 1,312,000              
      operating lease liabilities
                          -1,787,000 -1,846,000 -2,500,000                   
      right of use operating asset
                           1,771,000 2,942,000                   
      right of use assets obtained in exchange for new operating lease liabilities
                                               
      supplemental disclosure of non-cash investing and financing activities
                                               
      public offering costs included in accrued expenses
                            259,000    105,000               
      supplemental disclosure of non-cash operating, investing and financing activities
                                               
      supplemental disclosure of non-cash investing activities
                                               
      non-cash licensing and consulting fees
                                         787,000 424,000   
      increase in restricted cash
                                           
      net increase in cash and cash equivalents
                                 171,319,000 1,466,000 -12,010,000 -23,057,000 -151,561,000 131,075,000 -110,677,000 112,927,000 -18,124,000 -19,357,000 111,072,000 -14,604,000 -8,961,000 87,600,000 
      cash and cash equivalents at beginning of period
                                 168,517,000 186,753,000 127,766,000 
      cash and cash equivalents at end of period
                                 171,319,000 1,466,000 -12,010,000 145,460,000 -151,561,000 131,075,000 -110,677,000 299,680,000 -18,124,000 -19,357,000 111,072,000 113,162,000 -8,961,000 87,600,000 
      supplemental disclosure of non-cash financing activities
                                               
      public offering costs included in accounts payable or accrued expenses
                                         161,000 -133,000     
      purchases of property and equipment included in accounts payable or accrued expenses
                                    64,000    279,000       
      proceeds from the issuance of series b preferred stock, net of issuance costs
                                             
      proceeds from the issuance of series c preferred stock, net of issuance costs
                                             
      accretion of redeemable convertible preferred stock to redemption value
                                             391,000 
      conversion of preferred stock to common stock
                                               
      proceeds from sales of marketable securities
                                               
      purchase of property and equipment
                                        -341,000 -38,000 21,000 -71,000 -110,000 -45,000 -78,000 
      payment of offering costs
                                        -599,000 -36,000 -90,000 -423,000 -35,000 -250,000 -1,128,000 
      proceeds from public offering of common stock, net of commissions and underwriting discounts
                                        141,000,000     
      deferred offering costs
                                               
      proceeds from the issuance of series a preferred stock, net of issuance costs
                                               
      proceeds from stock option exercise and employee stock purchase plan issuances
                                               
      depreciation and amortization
                                           32,000 22,000 16,000 13,000 
      accrued expenses and other
                                           35,000 261,000  1,186,000 
      proceeds from stock option exercises and restricted stock
                                               
      proceeds from the issuance of common stock and restricted stock
                                            147,000 1,000 37,000 
      deferred public offering costs included in accounts payable or accrued expenses
                                            151,000   
      licensing or consulting fees paid in common stock
                                             
      accrued expenses
                                               
      other liabilities
                                               
      proceeds from initial public offering of common stock, net of commissions and underwriting discounts
                                              
      conversion of redeemable convertible preferred stock to common stock
                                               
      changes in operating assets and liabilities
                                               
      proceeds from convertible notes payable
                                               
      initial public offering costs included in accounts payable or accrued expenses
                                               
      deferred initial public offering costs included in accounts payable or accrued expenses
                                               
    The information provided in this report is taken from www.sec.gov and many other data providers. While we have conducted our best efforts to ensure that the parsed data is accurate, we cannot guarantee its accuracy. Please use caution and understand that any consequences of its use are your own responsibility.