Quarterly
Annual
| Unit: USD | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | 2017-12-31 | 2017-09-30 | 2017-06-30 | 2017-03-31 | 2016-12-31 | 2016-09-30 | 2016-06-30 | 2016-03-31 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
collaboration revenue | 13,782,000 | 14,245,000 | 16,627,000 | 9,111,000 | 6,957,000 | 28,935,000 | 11,992,000 | 13,594,000 | 12,606,000 | 13,266,000 | 14,030,000 | 11,252,000 | 12,854,000 | 7,204,000 | 6,550,000 | 6,445,000 | 6,595,000 | 22,220,000 | 16,263,000 | 12,916,000 | 10,936,000 | 10,616,000 | 11,118,000 | 10,433,000 | 7,880,000 | 7,408,000 | 7,677,000 | 7,469,000 | 6,668,000 | 7,317,000 | 5,917,000 | 6,215,000 | 2,713,000 | 4,869,000 | 4,206,000 | 1,777,000 |
yoy | 98.10% | -50.77% | 38.65% | -32.98% | -44.81% | 118.11% | -14.53% | 20.81% | -1.93% | 84.15% | 114.20% | 74.58% | 94.91% | -67.58% | -59.72% | -50.10% | -39.69% | 109.31% | 46.28% | 23.80% | 38.78% | 43.30% | 44.82% | 39.68% | 18.18% | 1.24% | 29.74% | 20.18% | 145.78% | 50.28% | 40.68% | 249.75% | ||||
qoq | -3.25% | -14.33% | 82.49% | 30.96% | -75.96% | 141.29% | -11.78% | 7.84% | -4.98% | -5.45% | 24.69% | -12.46% | 78.43% | 9.98% | 1.63% | -2.27% | -70.32% | 36.63% | 25.91% | 18.11% | 3.01% | -4.52% | 6.57% | 32.40% | 6.37% | -3.50% | 2.78% | 12.01% | -8.87% | 23.66% | -4.79% | 129.08% | -44.28% | 15.76% | 136.69% | |
operating expenses: | ||||||||||||||||||||||||||||||||||||
research and development | 94,747,000 | 97,035,000 | 108,427,000 | 123,380,000 | 114,207,000 | 111,847,000 | 113,696,000 | 115,276,000 | 97,116,000 | 96,651,000 | 90,199,000 | 133,095,000 | 71,161,000 | 60,486,000 | 58,884,000 | 39,276,000 | 38,231,000 | 39,756,000 | 37,771,000 | 34,650,000 | 31,731,000 | 27,513,000 | 25,460,000 | 23,709,000 | 19,918,000 | 23,237,000 | 23,467,000 | 22,493,000 | 21,170,000 | 17,481,000 | 15,565,000 | 13,431,000 | -19,404,000 | 7,861,000 | 7,423,000 | 5,225,000 |
general and administrative | 30,512,000 | 27,206,000 | 29,007,000 | 30,501,000 | 31,793,000 | 31,091,000 | 29,403,000 | 30,652,000 | 27,448,000 | 22,145,000 | 22,132,000 | 22,403,000 | 22,108,000 | 18,711,000 | 16,683,000 | 13,594,000 | 10,763,000 | 10,566,000 | 11,526,000 | 11,314,000 | 8,976,000 | 8,431,000 | 13,118,000 | 10,533,000 | 8,708,000 | 8,270,000 | 7,805,000 | 7,406,000 | 10,213,000 | 5,711,000 | 6,369,000 | 5,732,000 | -9,301,000 | 4,705,000 | 3,729,000 | 3,246,000 |
total operating expenses | 125,259,000 | 124,241,000 | 137,434,000 | 153,881,000 | 146,000,000 | 142,938,000 | 143,099,000 | 145,928,000 | 124,564,000 | 118,796,000 | 112,331,000 | 155,498,000 | 93,269,000 | 79,197,000 | 75,567,000 | 52,870,000 | 48,994,000 | 50,322,000 | 49,297,000 | 45,964,000 | 40,707,000 | 35,944,000 | 38,578,000 | 34,242,000 | 28,626,000 | 31,507,000 | 31,272,000 | 29,899,000 | 31,383,000 | 23,192,000 | 21,934,000 | 19,163,000 | -22,650,000 | 12,566,000 | 11,152,000 | 8,471,000 |
operating income | -111,477,000 | -109,996,000 | -120,807,000 | -144,770,000 | -139,043,000 | -114,003,000 | -131,107,000 | -132,334,000 | -111,958,000 | -105,530,000 | -98,301,000 | -144,246,000 | -80,415,000 | -71,993,000 | -69,017,000 | -46,425,000 | -42,399,000 | -28,102,000 | -33,034,000 | -33,048,000 | -29,771,000 | -25,328,000 | -27,460,000 | -23,809,000 | -20,746,000 | -24,099,000 | -23,595,000 | -22,430,000 | -24,715,000 | -15,875,000 | -16,017,000 | -12,948,000 | 11,798,000 | -7,697,000 | -6,946,000 | -6,694,000 |
yoy | -19.83% | -3.51% | -7.86% | 9.40% | 24.19% | 8.03% | 33.37% | -8.26% | 39.23% | 46.58% | 42.43% | 210.71% | 89.66% | 156.18% | 108.93% | 40.48% | 42.42% | 10.95% | 20.30% | 38.80% | 43.50% | 5.10% | 16.38% | 6.15% | -16.06% | 51.80% | 47.31% | 73.23% | -309.48% | 106.25% | 130.59% | 93.43% | ||||
qoq | 1.35% | -8.95% | -16.55% | 4.12% | 21.96% | -13.05% | -0.93% | 18.20% | 6.09% | 7.35% | -31.85% | 79.38% | 11.70% | 4.31% | 48.66% | 9.50% | 50.88% | -14.93% | -0.04% | 11.01% | 17.54% | -7.76% | 15.33% | 14.76% | -13.91% | 2.14% | 5.19% | -9.25% | 55.69% | -0.89% | 23.70% | -209.75% | -253.28% | 10.81% | 3.76% | |
operating margin % | -808.86% | -772.17% | -726.57% | -1588.96% | -1998.61% | -394.00% | -1093.29% | -973.47% | -888.13% | -795.49% | -700.65% | -1281.96% | -625.60% | -999.35% | -1053.69% | -720.33% | -642.90% | -126.47% | -203.12% | -255.87% | -272.23% | -238.58% | -246.99% | -228.21% | -263.27% | -325.31% | -307.35% | -300.31% | -370.65% | -216.96% | -270.69% | -208.33% | 434.87% | -158.08% | -165.15% | -376.70% |
other income, net: | ||||||||||||||||||||||||||||||||||||
interest income | 6,714,000 | 7,402,000 | 8,603,000 | 12,122,000 | 12,422,000 | 12,632,000 | 12,740,000 | 12,653,000 | 11,980,000 | 1,945,000 | 703,000 | 540,000 | 503,000 | 349,000 | 211,000 | 220,000 | 207,000 | 262,000 | 641,000 | 1,242,000 | 1,495,000 | 1,694,000 | 1,777,000 | 1,869,000 | 1,680,000 | 1,397,000 | 1,376,000 | 1,074,000 | 752,000 | 519,000 | 424,000 | 317,000 | 66,500 | 215,000 | 46,000 | 5,000 |
change in fair value of investments | 3,439,000 | 1,339,000 | -2,125,000 | -3,064,000 | -20,354,000 | -6,065,000 | ||||||||||||||||||||||||||||||
total other income | 10,153,000 | 8,741,000 | 6,478,000 | 9,058,000 | -7,932,000 | 6,567,000 | 8,883,000 | 8,653,000 | 8,832,000 | -7,699,000 | -2,377,000 | -2,626,000 | ||||||||||||||||||||||||
net income | -101,324,000 | -101,255,000 | -114,329,000 | -135,712,000 | -146,975,000 | -107,436,000 | -122,224,000 | -123,681,000 | -103,126,000 | -113,229,000 | -100,678,000 | -146,872,000 | -81,237,000 | -71,644,000 | -68,806,000 | -46,205,000 | -42,192,000 | -27,840,000 | -32,393,000 | -31,806,000 | -28,276,000 | -23,634,000 | -25,683,000 | -21,940,000 | -19,066,000 | -22,702,000 | -22,219,000 | -21,356,000 | -23,963,000 | -15,356,000 | -15,593,000 | -12,631,000 | 11,532,000 | -7,482,000 | -6,900,000 | -6,689,000 |
yoy | -31.06% | -5.75% | -6.46% | 9.73% | 42.52% | -5.12% | 21.40% | -15.79% | 26.94% | 58.04% | 46.32% | 217.87% | 92.54% | 157.34% | 112.41% | 45.27% | 49.21% | 17.80% | 26.13% | 44.97% | 48.31% | 4.11% | 15.59% | 2.73% | -20.44% | 47.84% | 42.49% | 69.08% | -307.80% | 105.24% | 125.99% | 88.83% | ||||
qoq | 0.07% | -11.44% | -15.76% | -7.66% | 36.80% | -12.10% | -1.18% | 19.93% | -8.92% | 12.47% | -31.45% | 80.79% | 13.39% | 4.12% | 48.91% | 9.51% | 51.55% | -14.06% | 1.85% | 12.48% | 19.64% | -7.98% | 17.06% | 15.07% | -16.02% | 2.17% | 4.04% | -10.88% | 56.05% | -1.52% | 23.45% | -209.53% | -254.13% | 8.43% | 3.15% | |
net income margin % | -735.19% | -710.81% | -687.61% | -1489.54% | -2112.62% | -371.30% | -1019.21% | -909.82% | -818.07% | -853.53% | -717.59% | -1305.30% | -632.00% | -994.50% | -1050.47% | -716.91% | -639.76% | -125.29% | -199.18% | -246.25% | -258.56% | -222.63% | -231.00% | -210.29% | -241.95% | -306.45% | -289.42% | -285.93% | -359.37% | -209.87% | -263.53% | -203.23% | 425.06% | -153.67% | -164.05% | -376.42% |
net income per share | -0.92 | -0.98 | -1.1 | -1.34 | -1.52 | -1.12 | -1.38 | -1.4 | -1.17 | -1.49 | -1.33 | -1.96 | -1.1 | -0.97 | -1.01 | -0.69 | -0.7 | -0.47 | -0.61 | -0.63 | -0.58 | -0.49 | -0.56 | -0.49 | -0.43 | -0.53 | -0.52 | -0.51 | -0.63 | -0.44 | -0.45 | -0.36 | -10.39 | -0.22 | -0.36 | -9.89 |
weighted-average shares outstanding, basic and diluted | 110,188 | 103,732 | 103,500 | 101,002 | 96,975 | 95,502 | 88,645 | 88,185 | 87,772 | 76,047 | 75,823 | 74,751 | 70,894 | 73,706 | 68,164 | 67,183 | 55,987 | 58,754 | 53,369 | 50,491 | 47,247 | 48,554 | 45,814 | 45,234 | 43,069 | 43,161 | 42,836 | 42,043 | 36,006 | 35,189 | 34,916 | 34,723 | 34,316 | 19,121 | 676 | |
other comprehensive gain: | ||||||||||||||||||||||||||||||||||||
unrealized gain on marketable securities | 337 | -404 | 452 | 4,452 | -208 | -821 | 142 | -1,482 | 2,989 | 991 | -13 | -30 | -124 | -218 | 112 | -75 | 81 | 196 | 87 | |||||||||||||||||
comprehensive loss | -100,987 | -101,659 | -113,877 | -131,260 | -147,183 | -108,257 | -121,928 | -124,871 | -98,343 | -113,043 | -102,170 | -152,302 | -83,695 | -71,805 | -68,807 | -46,218 | -42,222 | -27,964 | -32,611 | -31,694 | -28,351 | -23,553 | -25,487 | -21,853 | ||||||||||||
other comprehensive loss: | ||||||||||||||||||||||||||||||||||||
income from equity method investment | -3,857,000 | -4,000,000 | -3,048,000 | -1,834,000 | -3,252,000 | -2,745,000 | ||||||||||||||||||||||||||||||
change in fair value of contingent consideration | -100,000 | -7,810,000 | 172,000 | -421,000 | ||||||||||||||||||||||||||||||||
other comprehensive income: | ||||||||||||||||||||||||||||||||||||
other comprehensive gain from equity method investment | 154 | 292 | 1,794 | |||||||||||||||||||||||||||||||||
including the following revenue from related party | 1,946 | 5,792 | 4,935 | 4,414 | 7,767 | 5,384 | 69.25 | 277 | ||||||||||||||||||||||||||||
other comprehensive income from equity method investment | -805 | -560 | -302 | |||||||||||||||||||||||||||||||||
unrealized loss on marketable securities | -932 | -5,128 | -43.75 | -161 | -1 | |||||||||||||||||||||||||||||||
income before income taxes | 11,532,000 | -7,482,000 | -6,900,000 | -6,689,000 | ||||||||||||||||||||||||||||||||
income tax benefit | ||||||||||||||||||||||||||||||||||||
net income per common unit, basic and diluted | ||||||||||||||||||||||||||||||||||||
weighted-average common units outstanding, basic and diluted | ||||||||||||||||||||||||||||||||||||
benefit from income taxes |
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