Quarterly
Annual
| Unit: USD | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | 2017-12-31 | 2017-09-30 | 2017-06-30 | 2017-03-31 | 2016-12-31 | 2016-09-30 | 2016-06-30 | 2016-03-31 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
assets | |||||||||||||||||||||||||||||||||||||||
current assets: | |||||||||||||||||||||||||||||||||||||||
cash and cash equivalents | 193,389,000 | 156,172,000 | 126,880,000 | 189,182,000 | 120,495,000 | 130,849,000 | 171,979,000 | 226,748,000 | 168,027,000 | 171,806,000 | 294,150,000 | 523,506,000 | 141,194,000 | 147,781,000 | 133,382,000 | 123,406,000 | 334,736,000 | 129,879,000 | 141,538,000 | 160,020,000 | 179,746,000 | 361,687,000 | 80,993,000 | 57,226,000 | 38,440,000 | 49,140,000 | 47,097,000 | 58,856,000 | 293,248,000 | 305,538,000 | 327,778,000 | 340,678,000 | 222,264,000 | 241,047,000 | 257,551,000 | 273,064,000 | 290,618,000 | 300,687,000 | 64,192,000 |
marketable securities | 317,655,000 | 303,479,000 | 376,867,000 | 412,333,000 | 537,619,000 | 560,219,000 | 619,315,000 | 685,475,000 | 686,761,000 | 736,268,000 | 639,392,000 | 669,116,000 | 687,000,000 | 726,494,000 | 721,869,000 | 625,282,000 | 463,531,000 | 399,140,000 | 442,525,000 | 437,351,000 | 228,201,000 | 75,117,000 | 169,266,000 | 222,500,000 | 249,485,000 | 255,203,000 | |||||||||||||
accounts receivable | 11,050,000 | 11,353,000 | 10,504,000 | 8,517,000 | 8,854,000 | 12,329,000 | 36,427,000 | 36,456,000 | 6,491,000 | 5,056,000 | 4,906,000 | 3,768,000 | 4,023,000 | 2,854,000 | 1,801,000 | 2,031,000 | 2,491,000 | 1,993,000 | 953,000 | 2,130,000 | 1,217,000 | 3,864,000 | 13,368,000 | 4,620,000 | 3,599,000 | 4,188,000 | 3,591,000 | 7,547,000 | 2,813,000 | 8,609,000 | 7,466,000 | 10,471,000 | 4,493,000 | 2,764,000 | 2,443,000 | 6,454,000 | 1,112,000 | 1,000,000 | 1,000,000 |
prepaid expenses and other current assets | 59,847,000 | 24,941,000 | 37,141,000 | 29,831,000 | 43,934,000 | 53,814,000 | 56,322,000 | 49,651,000 | 32,214,000 | 26,485,000 | 25,223,000 | 20,407,000 | 26,730,000 | 18,304,000 | 18,315,000 | 18,584,000 | 14,016,000 | 18,392,000 | 16,068,000 | 17,016,000 | 7,086,000 | 5,699,000 | 6,133,000 | 5,135,000 | 6,414,000 | 4,710,000 | 3,520,000 | 3,371,000 | 2,768,000 | 3,482,000 | 2,476,000 | 3,681,000 | 2,296,000 | 2,108,000 | 1,084,000 | 1,788,000 | 972,000 | 1,217,000 | 745,000 |
total current assets | 581,941,000 | 495,945,000 | 551,392,000 | 639,863,000 | 710,902,000 | 757,211,000 | 884,043,000 | 998,330,000 | 893,493,000 | 939,615,000 | 963,671,000 | 1,216,797,000 | 858,947,000 | 895,433,000 | 875,367,000 | 769,303,000 | 814,774,000 | 549,404,000 | 601,084,000 | 616,517,000 | 416,250,000 | 446,367,000 | 269,760,000 | 289,481,000 | 295,935,000 | 307,137,000 | 303,693,000 | 324,977,000 | 298,829,000 | 317,629,000 | 337,720,000 | 354,830,000 | 229,053,000 | 245,919,000 | 261,078,000 | 281,306,000 | 292,702,000 | 302,904,000 | 65,937,000 |
marketable securities - noncurrent | 158,814,000 | 170,855,000 | 203,353,000 | 260,215,000 | 286,567,000 | 248,805,000 | 162,090,000 | 99,864,000 | 137,752,000 | 164,013,000 | 225,038,000 | 69,338,000 | 20,533,000 | 32,604,000 | 139,486,000 | 337,361,000 | 350,451,000 | 22,262,000 | 16,735,000 | 4,746,000 | 9,868,000 | 4,739,000 | |||||||||||||||||
property and equipment | 20,421,000 | 22,806,000 | 25,123,000 | 27,381,000 | 28,763,000 | 30,273,000 | 32,075,000 | 32,760,000 | 33,800,000 | 33,194,000 | 31,606,000 | 27,921,000 | 26,597,000 | 25,868,000 | 23,697,000 | 20,968,000 | 19,946,000 | 18,530,000 | 16,157,000 | 15,943,000 | 15,612,000 | 16,402,000 | 17,251,000 | 17,996,000 | 17,206,000 | 16,694,000 | 16,669,000 | 17,061,000 | 16,935,000 | 16,580,000 | 16,010,000 | 15,272,000 | 13,560,000 | 12,578,000 | 11,418,000 | 10,628,000 | 5,492,000 | 4,421,000 | 4,228,000 |
operating lease right-of-use assets | 117,883,000 | 129,045,000 | 137,979,000 | 219,292,000 | 100,331,000 | 105,412,000 | 110,424,000 | 115,375,000 | 118,775,000 | 123,550,000 | 128,265,000 | 133,076,000 | 101,290,000 | 73,775,000 | 76,473,000 | 79,143,000 | 81,788,000 | 77,070,000 | 77,912,000 | 39,114,000 | 22,210,000 | 23,469,000 | 24,918,000 | 19,137,000 | 20,663,000 | 20,923,000 | 21,012,000 | ||||||||||||
investments and other assets | 46,216,000 | 80,243,000 | 68,316,000 | 44,264,000 | 46,788,000 | 49,835,000 | 70,957,000 | 42,883,000 | 42,363,000 | 41,031,000 | 40,920,000 | 40,527,000 | 36,989,000 | 37,128,000 | 35,493,000 | 29,558,000 | |||||||||||||||||||||||
total assets | 925,275,000 | 898,894,000 | 986,163,000 | 1,191,015,000 | 1,173,351,000 | 1,191,536,000 | 1,259,589,000 | 1,300,977,000 | 1,243,349,000 | 1,323,240,000 | 1,417,889,000 | 1,520,114,000 | 1,084,458,000 | 1,110,424,000 | 1,202,788,000 | 1,294,464,000 | 1,334,961,000 | 672,243,000 | 716,891,000 | 676,322,000 | 458,555,000 | 490,830,000 | 314,752,000 | 334,280,000 | 346,635,000 | 352,441,000 | 344,363,000 | 347,315,000 | 321,233,000 | 339,778,000 | 359,545,000 | 376,235,000 | 249,170,000 | 264,975,000 | 279,263,000 | 298,969,000 | 301,469,000 | 310,624,000 | 75,540,000 |
liabilities and stockholders’ equity | |||||||||||||||||||||||||||||||||||||||
current liabilities: | |||||||||||||||||||||||||||||||||||||||
accounts payable | 13,260,000 | 9,802,000 | 12,364,000 | 14,589,000 | 13,145,000 | 18,816,000 | 13,689,000 | 7,452,000 | 3,553,000 | 11,634,000 | 6,890,000 | 5,154,000 | 4,384,000 | 7,515,000 | 10,138,000 | 9,653,000 | 7,470,000 | 6,854,000 | 8,688,000 | 10,460,000 | 7,775,000 | 7,000 | 3,870,000 | 3,941,000 | 4,548,000 | 1,848,000 | 3,687,000 | 2,708,000 | 1,754,000 | 335,000 | 1,916,000 | 2,172,000 | 2,194,000 | 2,267,000 | 1,434,000 | 4,652,000 | 657,000 | 1,042,000 | 1,206,000 |
accrued expenses | 40,841,000 | 41,553,000 | 40,805,000 | 55,355,000 | 51,206,000 | 45,127,000 | 43,276,000 | 67,017,000 | 57,979,000 | 49,534,000 | 44,822,000 | 60,876,000 | 58,379,000 | 44,871,000 | 42,876,000 | 43,309,000 | 24,633,000 | 37,150,000 | 21,215,000 | 25,554,000 | 19,348,000 | 15,374,000 | 13,102,000 | 13,273,000 | 11,644,000 | 11,898,000 | 7,735,000 | 10,742,000 | 9,893,000 | 9,156,000 | 6,605,000 | 7,999,000 | 5,939,000 | 5,312,000 | 3,559,000 | 5,900,000 | 4,810,000 | 4,288,000 | 2,973,000 |
current portion of operating lease liability | 27,378,000 | 26,990,000 | 38,763,000 | 20,246,000 | 19,177,000 | 18,963,000 | 18,763,000 | 18,599,000 | 17,074,000 | 16,750,000 | 16,328,000 | 16,685,000 | 13,551,000 | 9,568,000 | 9,338,000 | 9,112,000 | 8,705,000 | 7,415,000 | 8,255,000 | 5,696,000 | 6,198,000 | 5,834,000 | 5,693,000 | 5,745,000 | |||||||||||||||
current portion of deferred revenue | 12,247,000 | 17,154,000 | 20,661,000 | 20,661,000 | 22,155,000 | 22,184,000 | 22,184,000 | 22,140,000 | 13,347,000 | 21,933,000 | 35,343,000 | 43,839,000 | 54,818,000 | 61,806,000 | 63,759,000 | 63,759,000 | 56,759,000 | 22,544,000 | 22,544,000 | 22,544,000 | 22,544,000 | 37,927,000 | 12,639,000 | 12,674,000 | 15,822,000 | 19,652,000 | 23,431,000 | 27,122,000 | 14,268,000 | 15,678,000 | 17,062,000 | 21,188,000 | 17,653,000 | 18,792,000 | 19,917,000 | 20,178,000 | 17,166,000 | 16,287,000 | 6,781,000 |
total current liabilities | 93,726,000 | 95,499,000 | 112,593,000 | 110,851,000 | 105,683,000 | 105,090,000 | 97,912,000 | 115,208,000 | 91,953,000 | 99,851,000 | 103,383,000 | 126,554,000 | 131,132,000 | 123,760,000 | 126,111,000 | 125,833,000 | 97,567,000 | 73,963,000 | 60,702,000 | 64,254,000 | 55,865,000 | 59,142,000 | 35,304,000 | 35,633,000 | 37,519,000 | 38,463,000 | 39,234,000 | 40,572,000 | 25,915,000 | 25,169,000 | 25,583,000 | 31,359,000 | 25,786,000 | 26,371,000 | 24,910,000 | 30,730,000 | 22,633,000 | 21,617,000 | 10,960,000 |
deferred revenue, net of current portion | 12,539,000 | 12,539,000 | 13,161,000 | 18,256,000 | 22,607,000 | 28,052,000 | 33,440,000 | 38,853,000 | 12,719,000 | 12,919,000 | 13,862,000 | 19,932,000 | 25,678,000 | 35,330,000 | 49,481,000 | 63,476,000 | 63,023,000 | 40,208,000 | 45,829,000 | 51,387,000 | 57,070,000 | 62,752,000 | 13,020,000 | 16,136,000 | 19,322,000 | 22,508,000 | 25,659,000 | 28,810,000 | 31,996,000 | 35,181,000 | 38,332,000 | 44,111,000 | 47,336,000 | 50,785,000 | 54,092,000 | 58,109,000 | 60,406,000 | 65,042,000 | 2,753,000 |
long-term operating lease liability | 70,588,000 | 75,601,000 | 80,490,000 | 189,952,000 | 82,446,000 | 87,332,000 | 92,100,000 | 96,747,000 | 101,263,000 | 105,582,000 | 109,801,000 | 114,018,000 | 84,097,000 | 59,997,000 | 62,480,000 | 64,911,000 | 67,273,000 | 63,259,000 | 64,487,000 | 33,609,000 | 16,000,000 | 17,349,000 | 18,669,000 | 12,630,000 | |||||||||||||||
total liabilities | 176,853,000 | 183,639,000 | 206,244,000 | 319,059,000 | 210,736,000 | 220,474,000 | 223,452,000 | 250,808,000 | 205,935,000 | ||||||||||||||||||||||||||||||
commitments and contingencies | |||||||||||||||||||||||||||||||||||||||
stockholders’ equity: | |||||||||||||||||||||||||||||||||||||||
common stock | 12,000 | 10,000 | 10,000 | 10,000 | 10,000 | 10,000 | 10,000 | 9,000 | 9,000 | 9,000 | 9,000 | 9,000 | 8,000 | 8,000 | 8,000 | 7,000 | 7,000 | 7,000 | 7,000 | 7,000 | 6,000 | 6,000 | 5,000 | 5,000 | 5,000 | 5,000 | 5,000 | 5,000 | 4,000 | 4,000 | 4,000 | 4,000 | 4,000 | 4,000 | 4,000 | 4,000 | 4,000 | 4,000 | |
additional paid-in capital | 3,241,728,000 | 3,107,576,000 | 3,070,581,000 | 3,048,741,000 | 3,007,810,000 | 2,884,997,000 | 2,802,889,000 | 2,710,797,000 | 2,567,195,000 | 2,512,741,000 | 2,473,825,000 | 2,420,223,000 | 1,898,091,000 | 1,840,644,000 | 1,811,681,000 | 1,745,870,000 | 1,729,029,000 | 1,044,939,000 | 1,027,192,000 | 962,173,000 | 722,500,000 | 716,503,000 | 580,065,000 | 570,493,000 | 547,913,000 | 525,574,000 | 487,559,000 | 478,968,000 | 445,225,000 | 438,589,000 | 432,533,000 | 421,706,000 | 272,993,000 | 269,375,000 | 266,080,000 | 263,403,000 | 261,127,000 | 259,123,000 | 1,483,000 |
accumulated other comprehensive income | 990,000 | 653,000 | 1,057,000 | 605,000 | 3,297,000 | -13,000 | -12,000 | 1,000 | 31,000 | 155,000 | 373,000 | 261,000 | 336,000 | 255,000 | 59,000 | ||||||||||||||||||||||||
accumulated deficit | -2,494,308,000 | -2,392,984,000 | -2,291,729,000 | -2,177,400,000 | -2,048,502,000 | -1,912,790,000 | -1,765,815,000 | -1,658,379,000 | -1,526,218,000 | -1,403,994,000 | -1,280,313,000 | -1,177,187,000 | -1,063,780,000 | -950,551,000 | -849,873,000 | -703,001,000 | -621,764,000 | -550,120,000 | -481,314,000 | -435,109,000 | -392,917,000 | -365,077,000 | -332,684,000 | -300,878,000 | -272,602,000 | -248,968,000 | -223,285,000 | -201,025,000 | -181,959,000 | -159,257,000 | -137,038,000 | -121,113,000 | -97,150,000 | -81,794,000 | -66,201,000 | -53,570,000 | -43,007,000 | -35,525,000 | -28,625,000 |
total stockholders’ equity | 748,422,000 | 715,255,000 | 779,919,000 | 871,956,000 | 962,615,000 | 971,062,000 | 1,036,137,000 | 1,050,169,000 | 1,037,414,000 | 1,104,888,000 | 1,190,843,000 | 1,235,584,000 | 824,951,000 | 880,547,000 | 953,754,000 | 1,040,244,000 | 1,107,098,000 | 494,813,000 | 545,873,000 | 527,072,000 | 329,620,000 | 351,587,000 | 247,759,000 | 269,881,000 | 275,652,000 | 276,866,000 | 264,338,000 | 277,920,000 | 300,597,000 | 199,883,000 | 209,837,000 | 218,124,000 | 223,602,000 | ||||||
total liabilities and stockholders’ equity | 925,275,000 | 898,894,000 | 986,163,000 | 1,191,015,000 | 1,173,351,000 | 1,191,536,000 | 1,259,589,000 | 1,300,977,000 | 1,243,349,000 | 1,323,240,000 | 1,417,889,000 | 1,520,114,000 | 1,084,458,000 | 1,110,424,000 | 1,202,788,000 | 1,294,464,000 | 1,334,961,000 | 672,243,000 | 716,891,000 | 676,322,000 | 458,555,000 | 490,830,000 | 314,752,000 | 334,280,000 | 346,635,000 | 352,441,000 | 344,363,000 | 347,315,000 | 376,235,000 | 279,263,000 | 298,969,000 | 301,469,000 | 310,624,000 | ||||||
equity method investment | 11,765,000 | 17,166,000 | 21,837,000 | 28,389,000 | 32,455,000 | 40,102,000 | 45,616,000 | 52,272,000 | 58,131,000 | 62,837,000 | |||||||||||||||||||||||||||||
accumulated other comprehensive loss | -1,155,000 | -947,000 | -2,258,000 | -3,572,000 | -3,868,000 | -2,678,000 | -7,461,000 | -9,368,000 | -9,554,000 | -8,062,000 | -28,000 | ||||||||||||||||||||||||||||
contingent consideration liability | 24,026,000 | 18,600,000 | |||||||||||||||||||||||||||||||||||||
other long-term liabilities | 10,790,000 | 10,962,000 | 13,000 | 52,000 | 92,000 | 131,000 | 168,000 | 201,000 | 234,000 | 378,000 | 293,000 | 306,000 | 363,000 | 349,000 | |||||||||||||||||||||||||
accumulated other comprehensive (loss)/income | -2,632,000 | -174,000 | |||||||||||||||||||||||||||||||||||||
other assets | 5,165,000 | 4,977,000 | 5,003,000 | 4,748,000 | 4,483,000 | 4,592,000 | 2,823,000 | 2,920,000 | 2,963,000 | 2,948,000 | 2,989,000 | 5,277,000 | 5,469,000 | 5,569,000 | 5,815,000 | 6,133,000 | 6,557,000 | 6,478,000 | 6,767,000 | 7,035,000 | 3,275,000 | 3,299,000 | 5,375,000 | ||||||||||||||||
marketable securities - current | 247,482,000 | 221,959,000 | |||||||||||||||||||||||||||||||||||||
current portion of lease liability | 5,505,000 | 5,065,000 | 4,381,000 | ||||||||||||||||||||||||||||||||||||
long-term lease liability | 14,142,000 | 14,604,000 | 15,132,000 | ||||||||||||||||||||||||||||||||||||
proceeds due from at-the-market offerings | 27,140,000 | ||||||||||||||||||||||||||||||||||||||
liabilities and stockholders' equity | |||||||||||||||||||||||||||||||||||||||
stockholders' equity: | |||||||||||||||||||||||||||||||||||||||
total stockholders' equity | 263,270,000 | 279,336,000 | 295,499,000 | 175,847,000 | 187,585,000 | ||||||||||||||||||||||||||||||||||
total liabilities and stockholders' equity | 321,233,000 | 339,778,000 | 359,545,000 | 249,170,000 | 264,975,000 | ||||||||||||||||||||||||||||||||||
convertible preferred stock | |||||||||||||||||||||||||||||||||||||||
stockholders’ equity | |||||||||||||||||||||||||||||||||||||||
convertible preferred stock (series b, series a-2, series a-1, junior and founder), 0.0001 par value; 5,000,000 shares and 36,500,000 shares authorized, respectively; 0 shares and 36,316,628 shares issued and outstanding, respectively | |||||||||||||||||||||||||||||||||||||||
liabilities and stockholders’ deficit | |||||||||||||||||||||||||||||||||||||||
convertible preferred stock (series b, series a-2, series a-1, junior and founder), 0.0001 par value; 36,500,000 shares authorized and 36,316,628 shares issued and outstanding; aggregate liquidation preference of 95,946 | 88,620,000 | ||||||||||||||||||||||||||||||||||||||
stockholders’ deficit: | |||||||||||||||||||||||||||||||||||||||
total stockholders’ deficit | -27,142,000 | ||||||||||||||||||||||||||||||||||||||
total liabilities and stockholders’ deficit | 75,540,000 | ||||||||||||||||||||||||||||||||||||||
collaboration revenue | 1,777,000 | ||||||||||||||||||||||||||||||||||||||
operating expenses: | |||||||||||||||||||||||||||||||||||||||
research and development | 5,225,000 | ||||||||||||||||||||||||||||||||||||||
general and administrative | 3,246,000 | ||||||||||||||||||||||||||||||||||||||
total operating expenses | 8,471,000 | ||||||||||||||||||||||||||||||||||||||
operating income | -6,694,000 | ||||||||||||||||||||||||||||||||||||||
interest income | 5,000 | ||||||||||||||||||||||||||||||||||||||
income before income taxes | -6,689,000 | ||||||||||||||||||||||||||||||||||||||
benefit from income taxes | |||||||||||||||||||||||||||||||||||||||
net income | -6,689,000 | ||||||||||||||||||||||||||||||||||||||
net income per common unit, basic and diluted | |||||||||||||||||||||||||||||||||||||||
net income per share | -9,890 | ||||||||||||||||||||||||||||||||||||||
weighted-average common units outstanding, basic and diluted | |||||||||||||||||||||||||||||||||||||||
weighted-average shares outstanding, basic and diluted | 676,000 |
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