7Baggers

NeoGenomics, Inc
(NASDAQ:NEO) 

NEO stock logo

NeoGenomics, Inc. operates a network of cancer-focused testing laboratories in the United States, Europe, and Asia. It operates in two segments, Clinical Services and Pharma Services. The company offers testing services to hospitals, reference labs, pathologists, oncologists, clinicians, pharmaceuti...

Founded: 2002
Full Time Employees: 1,700
CEO: Douglas M. Van Oort  
Sector: Healthcare
Industry: Diagnostics & Research

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Quarterly
Annual
    Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 2014-06-30 2014-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31 2010-12-31 2010-09-30 2010-06-30 2010-03-31 2009-12-31 2009-09-30 2009-06-30 2009-03-31 2008-12-31 2008-09-30 2008-06-30 2008-05-13 2008-03-31 
                                                                              
      net revenue
    186,672,000 190,170,000 187,797,000 181,330,000 168,035,000                                     27,279,000 25,126,000 24,370,000 23,026,000 24,999,000 23,217,000 20,670,000 18,182,000 18,323,000 16,884,000 15,603,000 15,657,000 14,894,000 14,202,000 15,611,000 15,160,000 12,893,000 11,320,000 10,466,000 8,805,000  8,708 8,490 8,418,000 7,799,409 7,296,800 7,459,326 6,913,520  14,094,959 4,881,402 4,162,762 4,162,762 
      cost of revenue
    105,808,000 106,827,000 107,351,000 104,072,000 94,789,000 94,743,000 92,944,000 92,008,000 90,771,000 87,964,000 89,643,000 87,026,000 82,406,000 81,880,000 79,889,000 81,126,000 78,937,000 80,475,000 74,101,000 68,734,000 73,959,000 68,544,000 71,379,000 58,971,000 59,661,000 56,945,000 53,840,000 52,747,000 48,462,000 39,365,000 36,775,000 37,216,000 36,120,000 34,661,000 34,242,000 34,912,000 34,480,000 33,233,000 33,416,000 34,524,000 32,531,000 15,051,000 13,955,000 13,557,000 13,482,000 13,529,000 12,923,000 10,431,000 9,473,000 9,160,000 8,713,000 8,446,000 8,411,000 8,460,000 8,310,000 8,244,000 8,016,000 7,060,000 6,246,000 5,810,000 4,940,000  4,818 4,575 4,344,000 4,107,461 3,672,289 3,384,035 3,090,442  6,577,549 2,183,758 1,858,474 1,858,474 
      gross profit
    80,864,000 57,737,500 80,446,000 77,258,000 73,246,000 77,257,000 74,880,000 72,494,000 65,469,000 67,588,000 62,311,000 59,891,000 54,814,000 56,825,000 48,893,000 43,946,000 38,232,000 45,257,000 47,239,000 52,990,000 41,574,000 57,453,000 54,065,000 28,006,000 46,369,000 49,923,000 50,832,000 48,966,000 47,115,000 22,538,750 32,321,000 30,530,000 27,303,000 21,796,000 28,810,000 31,178,000          7,311,000 10,294,000 10,239,000  5,643,500 8,171,000 7,157,000  5,100,500 5,892,000 7,367,000  3,398,750 5,074,000 4,656,000   3,890 3,915  2,880,719.75 3,624,511 4,075,291 3,823,078  7,517,410 2,697,644 2,304,288 2,304,288 
      yoy
    10.40% -25.27% 7.43% 6.57% 11.88% 14.31% 20.17% 21.04% 19.44% 18.94% 27.44% 36.28% 43.37% 25.56% 3.50% -17.07% -8.04% -21.23% -12.63% 89.21% -10.34% 15.08% 6.36% -42.81% -1.58% 121.50% 57.27% 60.39% 72.56% 3.41% 12.19% -2.08%              29.55% 25.98% 43.06%  10.65% 38.68% -2.85%  50.07% 16.12% 58.23%   130337.02% 118827.20%   -99.89% -99.90%   -51.79% 51.07% 65.91%      
      qoq
    40.05% -28.23% 4.13% 5.48% -5.19% 3.17% 3.29% 10.73% -3.14% 8.47% 4.04% 9.26% -3.54% 16.22% 11.26% 14.95% -15.52% -4.20% -10.85% 27.46% -27.64% 6.27% 93.05% -39.60% -7.12% -1.79% 3.81% 3.93% 109.04% -30.27% 5.87% 11.82% 25.27% -24.35% -7.60%           -28.98% 0.54%   -30.93% 14.17%   -13.43% -20.02%   -33.02% 8.98%    -0.64%   -20.52% -11.06% 6.60%   178.67% 17.07% 0.00%  
      gross margin %
    Infinity% Infinity% Infinity% Infinity% Infinity% 63.25% 44.62% 44.07% 41.90% 43.45% 41.01% 40.77% 39.95% 40.97% 37.97% 35.14% 32.63% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% Infinity% Infinity% Infinity% NaN% Infinity% Infinity% Infinity% NaN% Infinity% Infinity% Infinity% NaN% Infinity% Infinity% Infinity% NaN% NaN% Infinity% Infinity% NaN% Infinity% Infinity% Infinity% Infinity% NaN% Infinity% Infinity% Infinity% Infinity% 
      operating expenses:
                                                                              
      general and administrative
    65,741,000 63,509,000 69,874,000 71,747,000 68,207,000 63,643,000 66,969,000 63,328,000 65,797,000 59,758,000 61,486,000 60,308,000 61,549,000 54,875,000 64,282,000 57,951,000 66,248,000 62,394,000 63,839,000 54,638,000 40,476,000 36,709,000 36,128,000 34,613,000 36,344,000 33,220,000 33,054,000 29,577,000 32,142,000 25,716,000 21,055,000 20,983,000 17,067,000 22,012,000 23,267,000 22,675,000 20,801,000 19,972,000 19,025,000 18,779,000 18,005,000 12,595,000 7,438,000 7,075,000 6,522,000 6,513,000 6,370,000 5,870,000 5,054,000 4,824,000 4,335,000 4,064,000 4,175,000 4,098,000 3,929,000 4,066,000 3,750,000 3,657,000 3,307,000 3,086,000 2,823,000  2,919 2,769 2,902,000 3,043,618 2,457,978  3,675,084  7,706,284 2,556,121 2,514,555 2,514,555 
      research and development
    9,534,000 9,179,000 8,694,000 9,023,000 10,181,000 7,969,000 7,684,000 7,886,000 7,620,000 7,127,000 5,285,000 7,502,000 7,395,000 6,675,000 7,312,000 8,626,000 7,713,000 8,513,000 7,409,000 3,495,000 2,456,000 2,100,000 1,964,000 2,105,000 2,060,000 2,080,000 2,611,000 2,587,000 1,209,000 526,000 446,000 1,073,000 956,000 556,000 1,270,000 947,000 862,000 930,000 967,000 1,306,000 1,446,000 1,856,000 871,000 803,000 669,000 414,000 1,014,000 633,000 628,000 649,000 340,000 616,000 835,000 448,000 808,000 528,000 497,000                  
      sales and marketing
    23,830,000 23,443,000 21,806,000 24,075,000 22,683,000 22,339,000 20,415,000 21,677,000 20,221,000 18,072,000 17,610,000 18,901,000 16,259,000 17,142,000 16,809,000 17,071,000 16,299,000 15,917,000 15,704,000 17,224,000 13,749,000 13,105,000 11,304,000 10,195,000 13,258,000 12,302,000 11,508,000 12,324,000 11,216,000 8,047,000 6,900,000 7,680,000 6,775,000 6,077,000 6,577,000 6,242,000 5,648,000 5,826,000 5,958,000 6,327,000 5,800,000 2,993,000 2,748,000 2,907,000 2,914,000 3,224,000 2,983,000 3,158,000 2,633,000 2,487,000 2,336,000 1,972,000 1,931,000 1,692,000 1,839,000 1,934,000 2,036,000 1,801,000 1,725,000 1,684,000 1,753,000  1,983 1,943 1,763,000 2,035,926 1,792,955        
      total operating expenses
    99,105,000 96,757,000 107,460,000 124,886,000 101,071,000 95,658,000 96,077,000 94,435,000 96,036,000 86,162,000 86,506,000 89,785,000 89,887,000 83,208,000 88,403,000 83,648,000 90,260,000 86,824,000 86,952,000 75,357,000 56,681,000 51,914,000 49,396,000 46,913,000 51,662,000 47,602,000 47,173,000 44,488,000 44,567,000 34,289,000 28,401,000 29,736,000 24,798,000 28,645,000 32,172,000 29,864,000 27,311,000 30,192,000 25,950,000 26,412,000 25,251,000 17,444,000 11,057,000 10,785,000 10,105,000 10,151,000 10,367,000 9,661,000 8,315,000 7,960,000 7,011,000 6,652,000 6,941,000 6,238,000 6,576,000 6,528,000 6,283,000 3,594,750 5,032,000 4,770,000 4,576,000  4,902 4,712 4,665,000 4,705,393 4,379,816 4,067,231 3,789,900  7,905,620 2,625,367 2,569,651 2,569,651 
      income from operations
    -18,241,000 -13,414,000 -27,014,000 -47,628,000 -27,825,000 -18,401,000 -21,197,000 -21,941,000 -30,567,000 -18,574,000 -24,195,000 -29,894,000 -35,073,000 -26,383,000 -39,510,000 -39,702,000 -52,028,000 -41,567,000 -39,713,000 -22,367,000 -15,107,000 5,539,000 4,669,000 -18,907,000 -5,293,000 2,321,000 3,659,000 4,478,000 2,548,000 2,821,000 3,920,000 794,000 2,505,000 4,487,000 -3,362,000 1,314,000 -115,000 -2,935,000 1,395,000 2,193,000 1,922,000 -5,216,000 114,000 28,000 -561,000 1,319,000 -73,000 578,000 394,000 1,203,000 1,160,000 505,000 305,000 196,000 -684,000 839,000 861,000 375,000 42,000 -114,000 -711,000  -1,012            
      yoy
    -34.44% -27.10% 27.44% 117.07% -8.97% -0.93% -12.39% -26.60% -12.85% -29.60% -38.76% -24.70% -32.59% -36.53% -0.51% 77.50% 244.40% -850.44% -950.57% 18.30% 185.41% 138.65% 27.60% -522.22% -307.73% -17.72% -6.66% 463.98% 1.72% -37.13% -216.60% -39.57% -2278.26% -252.88% -341.00% -40.08% -105.98% -43.73% 1123.68% 7732.14% -442.60% -495.45% -256.16% -95.16% -242.39% 9.64% -106.29% 14.46% 29.18% 513.78% -269.59% -39.81% -64.58% -47.73% -1728.57% -835.96% -221.10%  -4250.20%                
      qoq
    35.98% -50.34% -43.28% 71.17% 51.21% -13.19% -3.39% -28.22% 64.57% -23.23% -19.06% -14.77% 32.94% -33.22% -0.48% -23.69% 25.17% 4.67% 77.55% 48.06% -372.74% 18.63% -124.69% 257.21% -328.05% -36.57% -18.29% 75.75% -9.68% -28.04% 393.70% -68.30% -44.17% -233.46% -355.86% -1242.61% -96.08% -310.39% -36.39% 14.10% -136.85% -4675.44% 307.14% -104.99% -142.53% -1906.85% -112.63% 46.70% -67.25% 3.71% 129.70% 65.57% 55.61% -128.65% -181.53% -2.56% 129.60% 792.86% -136.84% -83.97%               
      operating margin %
    -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -15.07% -12.63% -13.34% -19.56% -11.94% -15.92% -20.35% -25.56% -19.02% -30.68% -31.74% -44.40% -Infinity% -Infinity% -Infinity% -Infinity% Infinity% Infinity% -Infinity% -Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% -Infinity% Infinity% -Infinity% -Infinity% Infinity% Infinity% Infinity% -Infinity% Infinity% Infinity% -Infinity% Infinity% -Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% -Infinity% Infinity% Infinity% Infinity% Infinity% -Infinity% -Infinity% NaN% -Infinity% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% 
      interest income
    -1,273,000 -1,523,000 -1,563,000 -2,263,000 -3,721,000 -4,328,000 -4,673,000 -4,592,000 -4,834,000                                                                  
      interest expense
    598,000 599,000 603,000 933,000 1,618,000 1,624,000 1,642,000 1,666,000 1,685,000 13,738,000 -2,840,000 -2,524,000 -1,467,000 -860,000 139,000 926,000 1,301,000 1,707,000 1,296,000 902,000 1,177,000 2,194,000 2,458,000 1,548,000 819,000 380,000 203,000 1,304,000 1,826,000 1,191,500 1,873,000 1,407,000 1,486,000 1,043,250 1,398,000 1,411,000 1,364,000 1,127,250 1,468,000 1,448,000 1,593,000                         -906,542 128,883 130,452 114,816  199,336 69,246 55,096 55,096 
      other expense
    12,000 -84,000 335,000 -482,000 -65,000 431,000 -317,000 2,000 263,000 -124,000 96,000 -730,000 114,000 1,000 -25,000 405,000     4,854,000 -4,222,000 -11,000 -7,405,000 -223,000 -494,000 -35,000 -10,000 5,169,000 -45,000 -30,000 124,000                                           
      loss before taxes
    -17,578,000 -12,406,000 -26,389,000 -45,816,000 -25,657,000 -16,128,000 -17,849,000 -19,017,000 -27,681,000 -15,286,000 -21,451,000 -26,640,000 -33,720,000    -53,161,000    -21,138,000    -5,889,000                                                  
      income tax expense
    -472,000 70,500 740,000  266,000            -3,753,000    976,000 -7,850,000 -335,000 -11,132,000 1,089,000 -3,861,000 1,348,000 175,000 -2,023,000 1,049,000 54,000 -357,000 438,000 -134,750 340,000 -54,000 -825,000 -2,201,000 -6,000 332,000 174,000                                  
      net income
    -17,106,000 -9,881,000 -27,129,000 -45,092,000 -25,923,000 -15,324,000 -17,699,000 -18,642,000 -27,061,000 -14,326,000 -18,516,000 -24,331,000 -30,795,000 -22,687,000 -36,852,000 -35,303,000 -49,408,000 -41,759,000 -20,348,000 75,873,000 -22,114,000 15,417,000 2,557,000 -6,824,000 -6,978,000 6,296,000 2,143,000 1,991,000 -2,424,000 353,000 2,023,000 -380,000 644,000 -1,449,250 -5,100,000 -43,000 -654,000 -6,223,000 -67,000 413,000 155,000 -1,473,000 -125,000 -176,000 -761,000 1,047,000 -291,000 274,000 102,000 857,000 900,000 273,000 3,000 -113,000 -975,000 551,000 603,000 152,000 -143,000 -293,000 -893,000  -1,198 -978 -750,000 -1,528,745 -755,305 8,060 33,178  -388,210 72,277 -265,363 -265,363 
      yoy
    -34.01% -35.52% 53.28% 141.88% -4.21% 6.97% -4.41% -23.38% -12.13% -36.85% -49.76% -31.08% -37.67% -45.67% 81.11% -146.53% 123.42% -370.86% -895.78% -1211.86% 216.91% 144.87% 19.32% -442.74% 187.87% 1683.57% 5.93% -623.95% -476.40% -124.36% -139.67% 783.72% -198.47% -76.71% 7511.94% -110.41% -521.94% 322.47% -46.40% -334.66% -120.37% -240.69% -57.04% -164.23% -846.08% 22.17% -132.33% 0.37% 3300.00% -858.41% -192.31% -50.45% -99.50% -174.34% 581.82% -288.05% -167.53%  11836.56% 29859.10% 19.07%  -99.84% -112.13% -2360.53%  94.56% -88.85% -112.50%      
      qoq
    73.12% -63.58% -39.84% 73.95% 69.17% -13.42% -5.06% -31.11% 88.89% -22.63% -23.90% -20.99% 35.74% -38.44% 4.39% -28.55% 18.32% 105.22% -126.82% -443.10% -243.44% 502.93% -137.47% -2.21% -210.83% 193.79% 7.63% -182.14% -786.69% -82.55% -632.37% -159.01% -144.44% -71.58% 11760.47% -93.43% -89.49% 9188.06% -116.22% 166.45% -110.52% 1078.40% -28.98% -76.87% -172.68% -459.79% -206.20% 168.63% -88.10% -4.78% 229.67% 9000.00% -102.65% -88.41% -276.95% -8.62% 296.71% -206.29% -51.19% -67.19%   22.49% -99.87% -50.94% 102.40% -9471.03% -75.71%   -637.11% -127.24% 0.00%  
      net income margin %
    -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -12.55% -10.55% -11.33% -17.32% -9.21% -12.19% -16.56% -22.44% -16.36% -28.62% -28.23% -42.17% -Infinity% -Infinity% Infinity% -Infinity% Infinity% Infinity% -Infinity% -Infinity% Infinity% Infinity% Infinity% -Infinity% Infinity% Infinity% -Infinity% Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% Infinity% Infinity% -Infinity% -Infinity% -Infinity% -Infinity% Infinity% -Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% -Infinity% -Infinity% Infinity% Infinity% Infinity% -Infinity% -Infinity% -Infinity% NaN% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% Infinity% Infinity% NaN% -Infinity% Infinity% -Infinity% -Infinity% 
      net income per share
                                             -0.005   -0.01                            -0.01 -0.01 
      basic
    -0.13 -0.07 -0.21 -0.35 -0.2 -0.12 -0.14 -0.15 -0.21 -0.11 -0.15 -0.19 -0.25 -0.18 -0.3 -0.28 -0.4 -0.35 -0.17 0.64 -0.19 0.14 0.02 -0.06 -0.07        -0.03 -0.043 -0.1 -0.03 -0.04 -0.053 -0.07 -0.07 -0.07                                  
      diluted
    -0.13 -0.07 -0.21 -0.35 -0.2 -0.12 -0.14 -0.15 -0.21 -0.11 -0.15 -0.19 -0.25 -0.18 -0.3 -0.28 -0.4 -0.35 -0.17 0.59 -0.19 0.14 0.04 -0.06 -0.07        -0.03 -0.043 -0.1 -0.03 -0.04 -0.053 -0.07 -0.07 -0.07                                  
      weighted-average common shares outstanding
                                                                              
      basic
    129,166 128,101 128,415 127,949 127,376 126,658 126,953 126,405 126,111 125,502 125,687 125,356 125,026 124,217 124,425 124,068 123,630 119,962 122,559 118,287 116,199 108,579 110,461 107,887 104,484 100,470 103,899 98,297 94,740 85,618 87,253 81,017 80,507 79,426 79,617 79,413 78,650 77,542 78,145 77,448 76,068 60,526                                 
      diluted
    129,166 128,101 128,415 127,949 127,376 126,658 126,953 126,405 126,111 125,502 125,687 125,356 125,026 124,217 124,425 124,068 123,630 119,962 122,559 131,237 116,199 111,794 119,191 107,887 104,484 103,615 107,880 102,336 94,740 91,568 90,899 90,168 80,507 79,426 79,617 79,413 78,650 77,542 78,145 77,448 76,068 60,526                                 
      restructuring charges
         1,707,000 1,009,000 1,544,000 2,398,000 1,205,000 2,125,000 3,074,000 4,684,000                                                              
      impairment charges
     626,000 7,086,000 20,041,000                                                                       
      income tax benefit
       -724,000  -804,000 -150,000 -375,000 -620,000 -960,000 -2,935,000 -2,309,000 -2,925,000 -2,837,000 -2,772,000 -5,730,000  -2,445,000 -2,822,000 -2,437,000                                                       
      clinical services
         105,426,500 145,783,000 141,388,000 134,535,000 130,058,000 127,553,000 123,156,000 114,869,000 108,166,000 106,162,000 105,635,000 98,791,000 104,053,000 102,227,000 101,405,000 96,487,000 106,738,000 108,733,000 73,884,000 92,982,000 93,404,000 92,565,000 88,982,000 86,210,000 65,913,000 59,449,000 59,540,000                                           
      advanced diagnostics
         16,715,000 22,041,000 23,114,000 21,705,000 25,494,000 24,401,000 23,761,000                                                               
      total net revenue
         122,141,500 167,824,000 164,502,000 156,240,000 155,552,000 151,954,000 146,917,000 137,220,000 138,705,000 128,782,000 125,072,000 117,169,000                                                          
      yoy
         -21.48% 10.44% 11.97% 13.86% 12.15% 17.99% 17.47% 17.11%                                                              
      qoq
         -27.22% 2.02% 5.29% 0.44% 2.37% 3.43% 7.07% -1.07% 7.71% 2.97% 6.74%                                                           
      pharma services
                22,351,000 30,539,000 22,620,000 19,437,000 18,378,000 21,679,000 19,113,000 20,319,000 19,046,000 19,259,000 16,711,000 13,093,000 13,048,000 13,464,000 12,107,000 12,731,000 9,367,000 10,562,000 9,647,000 8,206,000 6,452,000 8,713,000 6,866,000 6,299,000 4,986,000                                      
      gain on investment in and loan receivable from non-consolidated affiliate
                      -17,750,000 -96,534,000                                                       
      income before taxes
                 -33,454,500 -39,624,000 -41,033,000  -44,204,000 -23,170,000 73,436,000  7,567,000 2,222,000 -17,956,000  2,435,000 3,491,000 2,166,000 -4,447,000 1,402,000 2,077,000 -737,000 1,082,000 -1,584,000 -4,760,000 -97,000 -1,479,000 -8,424,000 -73,000 745,000 329,000     1,126,000 -291,000 325,000  963,000 929,000 273,000                       
      adjustment to net income for convertible notes in diluted eps
                                                                              
      convertible note accretion, amortization, and interest, net of tax
                       1,552,000   1,975,000                                                    
      net income used in diluted eps
                   -35,303,000  8,353,000 -20,348,000 77,425,000  -2,811,250 4,532,000                                                    
      other expenses
                    -168,000                                                          
      net revenue:
                                                                              
      total revenue
                     89,649,250 121,340,000 121,724,000 115,533,000 79,612,750 125,444,000 86,977,000 106,030,000 106,868,000 104,672,000 101,713,000 95,577,000 76,475,000 69,096,000 67,746,000 63,423,000 67,793,000 63,052,000 66,090,000 61,676,000 60,490,000 60,761,000 63,129,000 59,704,000                                  
      other income
                     -107,750 -89,000 -171,000             -63,000                                          
      loss on extinguishment of debt
                           1,400,000    1,018,000                                               
      loss on termination of cash flow hedge
                           3,506,000                                                   
      adjustment to the numerator for convertible notes in diluted eps
                                                                              
      deemed dividends on preferred stock and amortization of beneficial conversion feature
                                                                              
      gain on redemption of preferred stock
                                   -9,075,000                                           
      net income attributable to common stockholders
                             6,296,000 2,143,000 1,991,000 -2,424,000 353,000 2,023,000 5,924,000                                           
      income per share attributable to common stockholders
                                                                              
      basic
                             0.06 0.02 0.02 -0.03 0.018 0.02 0.07                                           
      diluted
                             0.06 0.02 0.02 -0.03 0.015 0.02 0.07                                           
      weighted-average common shares outstanding:
                                                                              
      basic
    129,166 128,101 128,415 127,949 127,376 126,658 126,953 126,405 126,111 125,502 125,687 125,356 125,026 124,217 124,425 124,068 123,630 119,962 122,559 118,287 116,199 108,579 110,461 107,887 104,484 100,470 103,899 98,297 94,740 85,618 87,253 81,017 80,507 79,426 79,617 79,413 78,650 77,542 78,145 77,448 76,068 60,526                                 
      diluted
    129,166 128,101 128,415 127,949 127,376 126,658 126,953 126,405 126,111 125,502 125,687 125,356 125,026 124,217 124,425 124,068 123,630 119,962 122,559 131,237 116,199 111,794 119,191 107,887 104,484 103,615 107,880 102,336 94,740 91,568 90,899 90,168 80,507 79,426 79,617 79,413 78,650 77,542 78,145 77,448 76,068 60,526                                 
      deemed dividends on preferred stock
                                 8,248,000  947,000 1,003,000 911,000 912,000 929,000 894,000 12,491,000 1,840,000 1,840,000 1,840,000                                  
      amortization of preferred stock beneficial conversion feature
                                 -8,248,000  1,824,000 1,853,000 1,780,000 1,739,000 1,710,000 1,672,000 -4,517,000 3,727,000 3,727,000 3,727,000                                  
      loss on sale of path logic
                                      1,058,000                                        
      clinical testing
                                    56,971,000 43,167,000 56,186,000 59,791,000 56,690,000                                      
      net loss attributable to common stockholders
                                    -2,212,000 2,260,000 -7,751,000 -2,682,000 -3,220,000 -4,050,000 -5,634,000 -5,154,000 -5,412,000                                  
      gross margin
                                        27,196,000 27,257,000 27,345,000 28,605,000 27,173,000 12,228,000 11,171,000 10,813,000 9,544,000    8,709,000    7,246,000    7,144,000    3,865,000    4,074,000          
      clinical testing revenue
                                         41,668,500 55,739,000 56,316,000 54,622,000                                  
      pharma services & research revenue
                                         4,229,750 5,022,000                                    
      biopharma & research revenue
                                           6,813,000 5,082,000                                  
      operating expenses
                                                                              
      interest and other expense – net
                                             -155,750 -239,000 -189,000                               
      income before income taxes
                                             -260,500 -125,000 -161,000 -756,000    129,000    20,000    603,000                  
      income taxes
                                             5,000  15,000 5,000 79,000  51,000 27,000 106,000 29,000  17,000                      
      net income per share
                                             -0.005   -0.01                            -0.01 -0.01 
      weighted-average number of shares outstanding – basic
                                              60,537 60,425 60,277 53,483    48,263    45,027,010                     
      weighted-average number of shares outstanding – diluted
                                              60,537 60,425 60,277 56,016    52,775    48,715,063                     
      interest and other expense - net
                                                195,000                              
      interest and other income – net
                                                 -184,000 -218,000 -253,000  -187,250 -231,000 -232,000  -309,000 -291,000 -288,000                   
      - basic
                                                 12,818 -0.01 0.01 49,277 0.005 0.02 0.01 46,264 11,236 -0.02  0.01       -0.03 -0.02   33,066,941 32,173,698  -0.01 31,367,144   
      - diluted
                                                 13,481.5 -0.01 0.01 53,469 0.005 0.02 0.01 50,923 12,056.5 -0.02  0.01       -0.03 -0.02   38,485,914 35,630,058  -0.01 38,243,857   
      weighted avg number of shares outstanding
                                                                              
      interest income—net
                                                    -265,000                          
      weighted-average number of shares outstanding
                                                                              
      interest income - net
                                                        -285,000    -258,000    -182,000    -159,000          
      net income before taxes
                                                         44,500 -975,000 551,000                   
      – basic
                                                           0.01                   
      – diluted
                                                           0.01                   
      benefit for income taxes
                                                                              
      interest and other income — net
                                                             -136,250 -185,000                
      — basic and diluted
                                                             -0.008 43,103,707                
      interest and other income - net
                                                               -179,000   -186 -181           
      - basic and diluted
                                                               -0.01 -0.02  -0.03            
      weighted average number of shares outstanding
                                                                              
      income (loss) from operations
                                                                   -797           
      income / (loss) from operations
                                                                    -591,000          
      — basic
                                                                     -0.005 -0.02        
      — diluted
                                                                     -0.005 -0.02        
      selling, general and administrative
                                                                       3,936,779       
      net income (loss) per share
                                                                              
      other operating expenses
                                                                              
      weighted average number of shares outstanding – basic and fully diluted
                                                                            31,400,947  
      weighted-average number of shares outstanding – basic and fully diluted
                                                                             31,400,947 
    Balance Sheets:
    Quarterly
    Annual
      Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 2014-06-30 2014-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31 2010-12-31 2010-09-30 2010-06-30 2010-03-31 2009-12-31 2009-09-30 2009-06-30 2009-03-31 2008-12-31 2008-09-30 2008-06-30 2008-05-13 2008-03-31 
                                                                                
        assets
                                                                                
        current assets
                                                                                
        cash and cash equivalents
      146,143,000 159,618,000 164,117,000 154,723,000 346,194,000 367,012,000 361,992,000 355,085,000 331,914,000 342,488,000 306,239,000 289,074,000 275,609,000 263,180,000 266,126,000 283,637,000 305,896,000 316,827,000 340,565,000 368,796,000 611,970,000 228,713,000 233,233,000 295,281,000 86,254,000 173,016,000 178,891,000 167,436,000 13,195,000 9,811,000 118,440,000 9,435,000 15,173,000 12,821,000 12,211,000 10,932,000 11,036,000 12,525,000 28,935,000 21,786,000 19,256,000 23,420,000 33,966,000 32,952,000 31,248,000 33,689,000 34,366,000 5,023,000 5,385,000 4,834,000 4,929,000 4,636,000 4,628,000 1,868,000 2,038,000 2,566,000 2,756,000 2,628,000 2,649,000 2,632,000 2,533,000 1,097,000 1,555,000 2,177,000 1,661,000 1,631,069 3,128,047 697,722 857,190 468,171 631,365 442,187 330,358 330,358 
        accounts receivable
      167,424,000 159,242,000 155,296,000 153,125,000 151,208,000 150,540,000 151,428,000 146,581,000 140,279,000 131,227,000 132,640,000 125,425,000 118,842,000 119,711,000 111,994,000 111,276,000 110,796,000 112,130,000 104,964,000 106,284,000 102,922,000 106,843,000 103,697,000 87,766,000 99,972,000 94,242,000 91,133,000 89,991,000 82,585,000 76,919,000 62,694,000 60,765,000 58,129,000 60,427,000 62,723,000 61,750,000 61,718,000 55,512,000 50,184,000 53,513,000 50,088,000 48,943,000 21,556,000 21,130,000 21,484,000 20,475,000 18,297,000 18,800,000 19,262,000 18,653,000 15,727,000 16,005,000 15,628,000 14,034,000 12,013,000 11,327,000 10,683,000 7,894,000 7,366,000 7,155,000 6,191,000 5,236,000 5,630,000 5,385,000 5,492,000 4,632,219 4,174,624 4,171,363 3,955,266 2,913,531 3,381,066 3,641,822 2,937,905 2,937,905 
        inventories
      29,837,000 28,566,000 28,460,000 34,171,000 29,772,000 26,748,000 24,457,000 23,214,000 20,320,000 24,156,000 24,053,000 24,945,000 24,432,000 24,277,000 23,799,000 21,863,000 23,840,000 23,395,000 21,834,000 21,384,000 21,382,000 29,526,000 20,643,000 21,627,000 20,286,000 14,405,000 12,632,000 8,733,000 9,670,000 8,650,000 6,829,000 6,898,000 7,515,000 7,474,000 6,088,000 5,457,000 5,970,000 6,253,000 5,952,000 5,545,000 5,334,000 5,108,000 2,967,000 3,416,000 2,595,000 2,616,000 2,970,000 2,616,000 2,003,000 2,301,000 2,068,000 1,738,000 1,646,000 1,859,000 1,906,000 1,526,000 1,312,000 1,202,000 1,096,000 1,079,000 911,000 887,000 768,000 807,000 582,000 601,802 613,631 598,612 577,730 491,459 344,608 364,259 245,986 245,986 
        prepaid assets
      23,666,000 21,443,000 21,986,000 22,831,000 22,980,000 20,165,000 18,235,000 17,396,000 19,155,000 17,987,000 18,676,000 16,571,000 16,185,000 15,237,000 16,511,000 16,662,000 14,341,000 12,354,000 14,618,000 13,959,000 11,073,000 11,547,000 10,459,000 8,300,000 6,884,000 6,327,000 8,742,000 9,553,000 7,504,000 7,727,000                                             
        other current assets
      6,614,000 7,417,000 10,528,000 9,785,000 11,892,000 11,722,000 8,308,000 9,157,000 9,312,000 8,239,000 9,317,000 8,433,000 7,622,000 8,077,000 7,516,000 6,506,000 20,693,000 8,189,000 15,755,000 8,422,000 4,675,000 4,555,000 3,968,000 6,026,000 2,046,000 2,748,000 603,000 632,000 2,991,000 561,000 6,307,000 6,161,000 6,954,000 4,241,000 4,725,000 5,218,000 5,857,000 4,535,000 7,488,000 6,665,000 6,525,000 4,889,000 1,547,000 1,282,000 1,183,000 1,141,000 1,022,000 1,055,000 909,000 1,115,000 1,103,000 784,000 841,000 820,000 864,000 837,000 937,000 954,000 702,000 657,000 619,000 1,018,000 732,000 653,000 515,000 655,046 714,278 635,272 497,158 482,408 900,146 746,209 426,739 426,739 
        total current assets
      373,684,000 376,286,000 382,465,000 392,553,000 573,932,000 596,019,000 590,241,000 584,203,000 573,896,000 596,812,000 586,950,000 584,720,000 584,996,000 605,291,000 603,360,000 622,260,000 651,100,000 681,508,000 709,930,000 721,795,000 942,732,000 448,730,000 422,375,000 419,000,000 215,442,000 290,738,000 292,001,000 276,345,000 115,945,000 103,668,000 194,270,000 83,259,000 87,771,000 84,963,000 85,747,000 83,357,000 84,581,000 78,825,000 92,559,000 87,509,000 81,203,000 99,028,000 60,857,000 59,601,000 57,331,000 58,742,000 57,243,000 28,082,000 28,147,000 27,491,000 23,827,000 23,163,000 22,743,000 18,581,000 17,121,000 16,556,000 15,988,000 13,178,000 12,313,000 12,023,000 10,754,000 8,738,000 9,185,000 9,522,000 9,250,000 8,520,136 8,630,580 6,102,969 5,887,344 4,355,569 5,257,185 5,194,477 3,940,988 3,940,988 
        property and equipment
      83,659,000 84,834,000 85,470,000 85,462,000 89,603,000 94,103,000 93,038,000 92,158,000 87,865,000 92,012,000 94,517,000 100,110,000 102,845,000 102,499,000 106,818,000 111,105,000 108,942,000 109,465,000 107,172,000 112,208,000 94,315,000 85,873,000 85,449,000 83,969,000 83,392,000 64,188,000 62,488,000 59,334,000 60,696,000 60,888,000 41,004,000 42,873,000  36,504,000 34,549,000 35,588,000 36,531,000 34,036,000 34,169,000 33,575,000 33,559,000 34,577,000 15,898,000 16,286,000 16,640,000 15,082,000 14,637,000 12,974,000 11,472,000 9,694,000 8,592,000 8,437,000 8,045,000 8,607,000 9,234,000 8,410,000 7,355,000 6,642,000 5,062,000 4,559,000 4,553,000 4,839,000 5,010,000 5,042,000 4,882,000 4,339,560 4,180,162 3,190,587 2,857,025 2,875,297 2,495,146 2,215,613 2,032,537 2,032,537 
        operating lease right-of-use assets
      76,703,000 78,444,000 80,150,000 82,870,000 77,803,000 79,583,000 81,442,000 83,671,000 86,578,000 91,769,000 87,131,000 91,412,000 93,784,000 96,109,000 98,945,000 99,917,000 101,955,000 102,197,000 102,310,000 54,558,000 50,904,000 45,786,000 45,856,000 47,554,000 49,084,000 26,492,000 25,797,000 26,057,000 19,734,000                                              
        intangible assets
      278,895,000 286,528,000 294,162,000 301,795,000 331,319,000 339,681,000 348,042,000 356,404,000 364,764,000 373,128,000 381,910,000 390,693,000 399,477,000 408,260,000 416,848,000 425,338,000 433,835,000 442,325,000 450,802,000 471,038,000 118,195,000 120,653,000 123,353,000 125,821,000 128,289,000 126,640,000 129,084,000 135,301,000 137,844,000 140,029,000 69,909,000 71,330,000 72,751,000 74,165,000 76,330,000 73,614,000 75,339,000 77,064,000 82,346,000 84,164,000 85,774,000 87,800,000 3,928,000 4,022,000 4,119,000 4,212,000 4,236,000 2,466,000 2,521,000 2,577,000 2,633,000 2,689,000 2,744,000 2,800,000 2,856,000 2,912,000 2,968,000                  
        goodwill
      523,995,000 524,344,000 524,344,000 524,143,000 522,766,000 522,766,000 522,766,000 522,766,000 522,766,000 522,766,000 522,766,000 522,766,000 522,766,000 522,766,000 522,766,000 527,115,000 527,115,000 527,115,000 525,802,000 499,977,000 211,083,000 211,083,000 210,833,000 210,833,000 210,833,000 198,601,000 198,571,000 196,298,000 196,298,000 197,892,000 147,019,000 147,019,000 147,019,000 147,019,000 147,019,000 147,019,000 147,019,000 147,019,000 146,179,000 146,179,000 146,179,000 146,421,000 2,929,000 2,929,000 2,929,000 2,929,000 2,561,000                            
        other assets
      9,595,000 9,394,000 8,189,000 7,127,000 6,007,000 5,886,000 5,582,000 4,075,000 4,470,000 4,742,000 4,967,000 5,407,000 5,306,000 5,109,000 6,845,000 6,378,000 6,600,000 7,168,000 7,210,000 7,674,000 5,273,000 4,503,000 3,817,000 3,057,000 3,153,000 2,847,000 3,214,000 3,332,000 2,826,000 2,538,000 2,937,000 1,302,000 1,320,000 689,000 250,000 302,000 167,000 174,000 174,000 129,000 129,000 129,000 129,000 128,000 139,000 141,000 143,000 116,000 179,000 154,000 178,000 170,000 84,000 83,000 91,000 123,000 129,000 129,000   93,000 74,000 86,000 87,000 86,000 85,604 106,737 88,283 72,791 64,509 275,087 255,566 248,374 248,374 
        total non-current assets
      972,847,000 983,544,000 992,315,000 1,001,397,000 1,027,498,000 1,042,019,000 1,050,870,000 1,059,074,000 1,066,443,000 1,084,417,000 1,091,291,000 1,110,388,000 1,124,178,000 1,134,743,000 1,152,222,000 1,169,853,000 1,178,447,000 1,188,270,000 1,196,457,000 1,174,516,000 551,681,000 539,601,000                                                     
        total assets
      1,346,531,000 1,359,830,000 1,374,780,000 1,393,950,000 1,601,430,000 1,638,038,000 1,641,111,000 1,643,277,000 1,640,339,000 1,681,229,000 1,678,241,000 1,695,108,000 1,709,174,000 1,740,034,000 1,755,582,000 1,792,113,000 1,829,547,000 1,869,778,000 1,906,387,000 1,896,311,000 1,494,413,000 988,331,000 959,428,000 945,485,000 732,247,000 709,506,000 711,155,000 696,667,000 533,343,000 505,015,000 455,139,000 345,783,000 349,272,000 343,340,000 343,895,000 339,880,000 343,637,000 337,118,000 355,427,000 351,556,000 346,844,000 367,955,000 83,741,000 82,966,000 81,158,000 81,106,000 78,820,000 43,638,000 42,319,000 39,916,000 35,230,000 34,459,000 33,616,000 30,071,000 29,302,000 28,001,000 26,440,000 19,949,000 17,485,000 16,658,000 15,400,000 13,651,000 14,281,000 14,651,000 14,218,000 12,945,300 12,917,479 9,381,839 8,817,160 7,295,375 8,027,418 7,665,656 6,221,899 6,221,899 
        liabilities and stockholders’ equity
                                                                                
        current liabilities
                                                                                
        accounts payable
      25,898,000 23,090,000 22,611,000 27,492,000 16,211,000 21,607,000 16,514,000 17,186,000 18,336,000 20,334,000 16,819,000 17,913,000 22,712,000 20,510,000 13,708,000 16,849,000 20,481,000 17,921,000 28,536,000 23,056,000 18,919,000 24,965,000 17,735,000 19,198,000 20,453,000 19,568,000 17,995,000 16,326,000 16,514,000 17,779,000 9,200,000 12,337,000 13,048,000 10,450,000 14,823,000 15,594,000 20,579,000 16,782,000 13,984,000 13,435,000 15,288,000 12,464,000 5,026,000 6,059,000 5,465,000 6,294,000 6,287,000 6,081,000 4,701,000 4,177,000 3,780,000 3,387,000 2,925,000 3,611,000 3,238,000 3,134,000 3,316,000 2,529,000 2,285,000 2,463,000 1,722,000 1,933,000 1,869,000 2,049,000 1,762,000 1,968,884 2,106,696 1,554,015 1,695,518 1,512,427 1,904,694 1,902,813 1,609,775 1,609,775 
        accrued compensation
      40,576,000 47,580,000 51,301,000 48,557,000 39,487,000 62,443,000 52,165,000 50,880,000 34,609,000 53,161,000 47,594,000 45,686,000 32,891,000 40,141,000 37,992,000 37,280,000 32,320,000 38,304,000 32,283,000 38,719,000 23,621,000 24,727,000 26,083,000 22,065,000 20,810,000 21,365,000 26,298,000 19,621,000 18,851,000 19,062,000 15,187,000 11,184,000 10,164,000 9,482,000 11,805,000 7,782,000 7,697,000 8,351,000 11,382,000 8,577,000 9,185,000 6,217,000 4,767,000 3,940,000 3,394,000 3,897,000 3,410,000 3,411,000 2,210,000 2,337,000 2,375,000 2,291,000 1,889,000 2,808,000 2,194,000 2,314,000 1,617,000 2,137,000 1,291,000 1,401,000 907,000 1,338,000 1,083,000 1,275,000 1,007,000 1,308,160    736,552     
        accrued expenses and other liabilities
      12,727,000 12,003,000 17,393,000 18,479,000 18,628,000 12,624,000 22,998,000 17,274,000 18,134,000 15,069,000 18,679,000 18,172,000 17,964,000 15,070,000 20,420,000 16,075,000 16,571,000 17,796,000 18,088,000 25,304,000 14,018,000 11,654,000 8,677,000 7,913,000 8,966,000 7,548,000 7,900,000 7,893,000  8,986,000 7,517,000 9,889,000 9,884,000 6,144,000 5,000,000 3,186,000 2,766,000 4,247,000 4,380,000 7,604,000 4,980,000 7,374,000 1,332,000 1,231,000 1,237,000 1,208,000    741,000    669,000 690,000 691,000 818,000 773,000   426,000 460,000 622,000 508,000 439,000 464,830 1,200,988 1,220,807 1,328,220 358,265 955,405 1,203,374 1,280,212 1,280,212 
        current portion of operating lease liabilities
      4,828,000 4,776,000 4,507,000 4,052,000 3,075,000 3,381,000 3,716,000 3,574,000 4,487,000 5,610,000 6,213,000 7,354,000 6,934,000 6,584,000 6,379,000 5,708,000 5,958,000 6,884,000 6,988,000 5,642,000 5,111,000 4,967,000       3,620,000                                              
        contract liabilities
      561,000 851,000 1,576,000 1,084,000 1,163,000 409,000 589,000 972,000 1,144,000 2,130,000 3,617,000 5,712,000                                                               
        total current liabilities
      84,590,000 88,300,000 97,866,000 100,120,000 279,695,000 301,241,000 296,406,000 289,959,000 76,710,000 96,304,000 92,926,000 94,848,000 86,606,000 89,932,000 85,003,000 82,670,000 82,070,000 87,232,000 92,737,000 99,131,000 67,750,000 73,183,000 64,612,000 61,700,000 67,649,000 63,904,000 68,907,000 59,162,000 72,703,000 60,925,000 47,055,000 47,974,000 43,303,000 35,065,000 40,114,000 35,204,000 39,876,000 38,113,000 35,392,000 34,953,000 34,316,000 40,058,000 15,328,000 15,125,000 13,855,000 14,623,000 13,954,000 15,226,000 15,227,000 14,323,000 12,246,000 12,056,000 11,949,000 17,758,000 16,670,000 15,096,000 14,749,000 11,444,000 10,539,000 10,112,000 8,799,000 9,168,000 9,517,000 8,832,000 7,484,000 5,776,233 4,303,616 5,503,061 5,152,506 4,390,994 4,486,096 4,480,340 3,178,402 3,178,402 
        long-term liabilities
                                                                                
        operating lease liabilities
      61,461,000 62,822,000 64,325,000 66,616,000 59,861,000 60,841,000 62,172,000 63,294,000 64,773,000 67,871,000 62,007,000 65,468,000 67,319,000 68,952,000 70,471,000 71,882,000 73,434,000 72,289,000 72,336,000 49,624,000 46,437,000 42,296,000                                                     
        convertible senior notes
      342,240,000 341,858,000 341,476,000 341,095,000 340,714,000 340,335,000 339,956,000 339,577,000 538,923,000 538,198,000 537,475,000 536,755,000 536,037,000 535,322,000 534,609,000 533,898,000 533,189,000 532,483,000 531,779,000 531,077,000 530,378,000 168,120,000 166,440,000 164,544,000                                                   
        deferred income tax liabilities
      17,450,000 18,219,000 20,846,000 19,976,000 20,970,000 21,510,000 22,771,000 23,015,000 23,490,000 24,285,000 25,370,000 28,811,000 31,715,000 34,750,000 38,345,000 45,979,000 51,709,000 55,475,000 57,706,000 63,877,000 1,744,000 5,415,000                                                     
        other long-term liabilities
      12,030,000 12,069,000 11,977,000 12,103,000 11,921,000 11,772,000 11,596,000 11,548,000 13,033,000 13,034,000 13,035,000 13,034,000 13,035,000 13,055,000 14,166,000 14,165,000 14,141,000 13,951,000 14,432,000 3,796,000 3,707,000 4,056,000 3,937,000 3,155,000  3,566,000    3,060,000                                             
        total long-term liabilities
      433,181,000 434,968,000 438,624,000 439,790,000 433,466,000 434,458,000 436,495,000 437,434,000 640,219,000 643,388,000 637,887,000 644,068,000 648,106,000 652,079,000 657,591,000 665,924,000 672,473,000 674,269,000 676,405,000 648,822,000 582,949,000 220,854,000 228,453,000 229,556,000 159,555,000 138,194,000 145,241,000 147,771,000 136,792,000 123,647,000 104,525,000 133,600,000 97,953,000 102,742,000 104,123,000 108,102,000 109,737,000 112,409,000 73,943,000 73,235,000 72,356,000 89,785,000 6,564,000 6,974,000 7,148,000                              
        total liabilities
      517,771,000 523,268,000 536,490,000 539,910,000 713,161,000 735,699,000 732,901,000 727,393,000 716,929,000 739,692,000 730,813,000 738,916,000 734,712,000 742,011,000 742,594,000 748,594,000 754,543,000 761,501,000 769,142,000 747,953,000 650,699,000 294,037,000 293,065,000 291,256,000 227,204,000 202,098,000 214,148,000 206,933,000 209,495,000 184,572,000 151,580,000 181,574,000 141,256,000 137,807,000 144,237,000 143,306,000 149,613,000 150,522,000 109,335,000 108,188,000 106,672,000 129,843,000 21,892,000 22,099,000 21,003,000 20,701,000 19,755,000 20,505,000 19,824,000 18,205,000 14,903,000 15,019,000 14,786,000 20,855,000 20,080,000 18,282,000 17,770,000 14,052,000 12,125,000 11,369,000 10,014,000 10,516,000 10,906,000 10,268,000 9,115,000 7,301,961 5,869,960 7,034,007 6,523,840 5,794,265 5,540,417 5,334,633 4,068,870 4,068,870 
        commitments and contingencies
                                                                                
        stockholders’ equity
                                                                                
        common stock, 0.001 par value...
      129,000 129,000 128,000 128,000 128,000 128,000 128,000 128,000 127,000 127,000 127,000 127,000 127,000 127,000 127,000 126,000 125,000 124,000 123,000 123,000 117,000 112,000 111,000 110,000 105,000 105,000 104,000 104,000 95,000 94,000 93,000 81,000 81,000  80,000 79,000 79,000  78,000 78,000   61,000                                
        additional paid-in capital
      1,279,539,000 1,270,235,000 1,262,016,000 1,250,679,000 1,239,901,000 1,228,198,000 1,219,182,000 1,209,536,000 1,198,729,000 1,190,139,000 1,181,876,000 1,172,850,000 1,167,051,000 1,160,882,000 1,154,365,000 1,146,997,000 1,142,133,000 1,123,628,000 1,110,590,000 1,101,298,000 872,350,000 701,357,000 688,832,000 679,235,000 525,929,000 520,278,000 516,936,000 543,484,000 378,571,000 372,186,000 354,487,000 217,451,000 232,039,000 230,030,000 229,006,000 220,622,000 217,626,000 216,104,000 238,975,000 236,183,000 233,401,000 231,375,000 82,256,000 81,148,000 80,262,000 79,751,000 79,457,000 43,244,000 42,880,000 42,200,000 41,673,000 41,686,000 41,349,000 31,742,000 31,635,000 31,157,000 30,659,000 28,490,000 28,105,000 27,891,000 27,696,000 24,557,000 24,420,000 24,229,000 23,972,000 23,761,784 23,637,244 18,186,334 18,139,903 17,381,810 17,373,756 17,022,971 16,917,216 16,917,216 
        accumulated other comprehensive income
      4,000 4,000 71,000 29,000              -638,000 -390,000 -333,000 -150,000        -1,136,000 -579,000 536,000 257,000 499,000 274,000                                         
        accumulated deficit
      -450,912,000 -433,806,000 -423,925,000 -396,796,000 -351,704,000 -325,781,000 -310,457,000 -292,758,000 -274,116,000 -247,055,000 -232,729,000 -214,213,000 -189,882,000 -159,087,000 -136,400,000 -99,548,000 -64,245,000 -14,837,000   -28,603,000 -7,185,000 -22,602,000 -25,159,000 -18,335,000 -11,357,000 -17,653,000 -51,691,000 -53,682,000 -51,258,000 -51,557,000 -53,580,000 -60,074,000 -57,466,000 -59,553,000 -51,803,000 -49,120,000 -52,460,000 -38,263,000 -32,628,000 -27,475,000 -21,941,000 -20,468,000 -20,342,000 -20,167,000 -19,406,000 -20,452,000 -20,161,000 -20,435,000 -20,538,000 -21,395,000 -22,295,000 -22,568,000 -22,571,000 -22,458,000 -21,483,000 -22,034,000 -22,636,000 -22,788,000 -22,645,000 -22,353,000 -21,459,000 -21,082,000 -19,883,000 -18,906,000 -18,155,630 -16,626,885 -15,871,579 -15,879,639 -15,912,817 -14,918,441 -14,723,316 -14,795,594 -14,795,594 
        total stockholders' equity
      828,760,000  838,290,000 854,040,000                                                                       
        total liabilities and stockholders’ equity
      1,346,531,000  1,374,780,000 1,393,950,000 1,601,430,000 1,638,038,000 1,641,111,000 1,643,277,000 1,640,339,000 1,681,229,000 1,678,241,000 1,695,108,000 1,709,174,000 1,740,034,000 1,755,582,000 1,792,113,000 1,829,547,000 1,869,778,000 1,906,387,000 1,896,311,000  988,331,000    709,506,000                 83,741,000 82,966,000 81,158,000 81,106,000 78,820,000 43,638,000 42,319,000 39,916,000 35,230,000 34,459,000 33,616,000 30,071,000 29,302,000 28,001,000 26,440,000 19,949,000 17,485,000 16,658,000 15,400,000 13,651,000 14,281,000 14,651,000 14,218,000 12,945,300 12,917,479 9,381,839 8,817,160 7,295,375 8,027,418 7,665,656 6,221,899 6,221,899 
        marketable securities, at fair value
         8,962,000 11,886,000 19,832,000 25,821,000 32,770,000 52,916,000 72,715,000 96,025,000 120,272,000 142,306,000 174,809,000 177,414,000 182,316,000 175,534,000 198,563,000 202,144,000 202,950,000 190,710,000 67,546,000 50,375,000                                                    
        current portion of convertible senior notes
          201,131,000 200,777,000 200,424,000 200,073,000                                                                   
        total stockholders’ equity
       836,562,000   888,269,000 902,339,000 908,210,000 915,884,000 923,410,000 941,537,000 947,428,000 956,192,000 974,462,000 998,023,000 1,012,988,000 1,043,519,000 1,075,004,000 1,108,277,000 1,137,245,000 1,148,358,000 843,714,000 694,294,000 666,363,000 654,229,000 505,043,000 507,408,000 497,007,000 489,734,000 323,848,000 320,443,000 303,559,000 164,209,000 172,545,000 172,918,000 169,533,000 168,898,000 168,585,000 163,723,000 200,790,000 203,633,000 206,003,000 209,510,000 61,849,000 60,867,000 60,155,000 60,405,000 59,065,000 23,133,000 22,495,000 21,711,000 20,327,000 19,440,000 18,830,000 9,216,000 9,222,000 9,719,000 8,670,000 5,897,000 5,360,000 5,289,000 5,386,000 3,135,000 3,375,000 4,383,000 5,103,000 5,643,339 7,047,519 2,347,832 2,293,320 1,501,110 2,487,001 2,331,023 2,153,029 2,153,029 
        total liabilities and stockholders' equity
       1,359,830,000                   1,494,413,000  959,428,000 945,485,000 732,247,000  711,155,000 696,667,000 533,343,000                                              
        assets held for sale
        2,078,000 8,956,000              10,050,000 10,050,000                                                        
        liabilities held for sale
        478,000 456,000                                                                       
        accumulated other comprehensive loss
          -56,000 -206,000 -643,000 -1,022,000 -1,330,000 -1,674,000 -1,846,000 -2,572,000 -2,834,000 -3,899,000 -5,104,000 -4,056,000 -3,009,000     10,000 22,000 43,000 -2,656,000 -1,618,000 -2,380,000 -2,163,000                                               
        current portion of equipment financing obligations
                4,000 11,000 38,000 70,000 118,000 410,000 621,000 1,135,000 1,564,000 1,913,000 2,089,000 2,841,000                                                     
        pharma contract liabilities
                  6,067,000 7,557,000 6,386,000 6,348,000 6,119,000 5,192,000 5,278,000 4,497,000 3,992,000 4,029,000                                                     
        restricted cash
                        3,161,000 4,103,000 11,119,000 21,919,000                                 300,000 300,000 300,000 500,000 500,000 500,000 500,000 500,000 500,000 500,000 1,000,000 1,000,000         
        investment in non-consolidated affiliate
                          29,555,000 29,555,000 25,600,000 13,137,000                                                   
        prepaid lease asset
                         24,958,000 21,052,000 20,229,000 10,142,000 6,084,000 3,316,000                                                  
        equipment financing obligations
                       71,000 152,000 448,000 683,000 967,000                                                     
        retained earnings
                        26,922,000 47,270,000                                                       
        loan receivable from non-consolidated affiliate
                          10,185,000                                                      
        current portion of term loan
                                                                                
        term loan
                                                                                
        restricted cash, non-current
                            32,003,000 36,030,000 38,738,000                                                  
        short-term portion of financing obligations
                            3,700,000 4,458,000 4,941,000 5,432,000 5,750,000 5,825,000                                               
        short-term portion of operating leases
                            4,701,000 4,496,000 4,505,000  3,527,000 3,428,000                                               
        short-term portion of term loan
                              5,000,000 5,000,000 6,250,000 5,000,000  7,873,000    3,750,000    3,750,000    550,000                                 
        pharma contract liability
                            3,716,000 3,570,000 2,974,000 1,610,000 1,187,000 1,069,000 1,017,000 927,000 1,259,000 2,155,000                                           
        long-term portion of financing obligations
                            1,399,000 1,911,000 2,428,000 3,199,000 3,982,000 4,782,000                                               
        long-term portion of operating leases
                            43,123,000 44,524,000 45,910,000  23,870,000 24,179,000                                               
        long-term portion of term loan
                              90,605,000 91,829,000 93,027,000   87,880,000    66,616,000    70,149,000    52,254,000                                 
        deferred income tax liability
                            13,554,000 15,422,000 16,377,000 15,566,000 19,688,000 20,117,000 20,156,000 22,457,000 6,899,000 6,827,000 6,594,000 6,307,000 7,548,000 7,435,000 7,583,000 14,973,000 16,236,000 16,249,000 15,916,000 32,409,000 821,000 821,000 821,000 821,000 588,000 588,000 588,000 588,000                         
        stockholders' equity
                                                                                
        other long term liabilities
                              4,235,000  4,674,000 4,443,000 3,740,000                                              
        short-term portion of operating lease liabilities
                               3,381,000                                                 
        long-term portion of operating lease liabilities
                               24,034,000   16,648,000                                              
        revolving credit facility
                                  5,000,000 5,000,000  29,176,000 19,114,000 24,516,000 24,461,000 26,906,000 26,860,000     8,869,000                                 
        long-term portion of term loans
                                 94,250,000                                               
        accrued expenses and other current liabilities
                                  18,327,000                                              
        current portion of finance leases and obligations
                                  6,501,000                                              
        current portion of loans
                                  7,873,000                                              
        long-term portion of finance leases and obligations
                                  5,253,000                                              
        long-term portion of loans
                                  85,995,000  89,764,000 91,535,000 65,208,000  67,531,000 68,454,000 69,363,000  52,194,000 52,238,000 52,316,000                                  
        commitments and contingencies - see note l
                                                                                
        liabilities, redeemable convertible preferred stock and stockholders’ equity
                                                                                
        short-term portion of car loans
                                       49,000    92,000    50,000                                 
        short-term portion of capital leases
                                   6,298,000    5,190,000 4,687,000 4,812,000 4,997,000 4,891,000 5,000,000 4,691,000 4,267,000 4,534,000                                 
        long-term portion of car loans
                                       20,000    110,000    82,000                                 
        long-term portion of capital leases
                                   5,250,000    5,283,000 4,583,000 5,307,000 5,931,000 5,378,000 5,513,000 4,748,000 4,124,000 5,040,000                                 
        commitments and contingencies - see note m
                                                                                
        redeemable convertible preferred stock
                                                                                
        series a redeemable convertible preferred stock, 0.001 par value...
                                      35,471,000 32,615,000 30,125,000 27,676,000 25,439,000  45,302,000 39,735,000                                   
        total liabilities, redeemable convertible preferred stock and stockholders' equity
                                   505,015,000 455,139,000 345,783,000 349,272,000 343,340,000 343,895,000 339,880,000 343,637,000 337,118,000 355,427,000 351,556,000 346,844,000 367,955,000                                 
        short-term portion of capital leases and car loans
                                    6,675,000 5,847,000 5,988,000                                          
        short-term portion of loans
                                    7,217,000 6,562,000 4,219,000  3,799,000 3,830,000 3,837,000  646,000 646,000 596,000                                  
        long-term portion of capital leases and car loans
                                    6,663,000 5,414,000 6,515,000                                          
        long-term pharma contract liability
                                    1,199,000 648,000 522,000                                          
        commitments and contingencies - see note i
                                                                                
        property and equipment (net of accumulated depreciation of 44,024 and 40,530, respectively.
                                      40,411,000                                          
        commitments and contingencies - see note j
                                                                                
        common stock, .001 par value...
                                       80,000    79,000   77,000 76,000  61,000 60,000 60,000 60,000 50,000 50,000 49,000 49,000 49,000 49,000 45,000 45,000 45,000 45,000 43,000 43,000 43,000 43,000 37,000 37,000 37,000 37,000 37,185 37,160 33,077 33,056 32,117 31,686 31,368 31,407 31,407 
        series a redeemable convertible preferred stock, 0.01 par value...
                                           22,873,000   34,169,000 28,602,000                                 
        deferred income tax asset
                                               16,668,000 821,000 821,000 821,000 821,000 588,000 588,000 588,000 588,000                         
        commitments and contingencies - see note k
                                                                                
        short-term portion of equipment capital lease obligations
                                                4,203,000 3,895,000 3,759,000 3,224,000                             
        long-term portion of equipment capital lease obligations
                                                5,743,000 6,153,000 6,327,000 5,257,000                             
        commitments and contingencies (see note g) stockholders’ equity
                                                                                
        revolving credit line
                                                     1,989,000 4,864,000 4,282,000 2,736,000 3,193,000 4,190,000 8,458,000 8,035,000 6,393,000 6,686,000 3,898,000 4,472,000 3,819,000 3,863,000 3,442,000 3,900,000 2,969,000 2,453,000 552,033  1,858,187 1,419,033 1,146,850 1,176,221 1,053,471   
        long term liabilities
                                                                                
        total long term liabilities
                                                   6,078,000 5,801,000 5,279,000 4,597,000 3,882,000                         
        other accrued expenses and liabilities
                                                    1,100,000 651,000 461,000  755,000 631,000 662,000      625,000 573,000               
        short-term portion of equipment capital leases
                                                    3,157,000 3,094,000 2,991,000 2,786,000 2,600,000 2,554,000 2,283,000 2,212,000 2,513,000 2,564,000 2,312,000 2,107,000 1,866,000 1,856,000 1,881,000 1,995,000 2,043,000 2,031,000 1,823,000 1,482,326 995,932 870,052 709,735 636,900 449,776 320,682 288,415 288,415 
        long-term portion of equipment capital leases and notes payable
                                                    5,213,000                            
        commitments
                                                                                
        long-term portion of equipment capital leases
                                                     4,691,000 4,009,000 3,294,000 2,657,000 2,963,000 2,837,000 3,097,000 3,410,000 3,186,000 3,021,000 2,608,000 1,586,000 1,257,000 1,215,000 1,348,000 1,389,000 1,436,000 1,631,000 1,525,728 1,566,344 1,530,946 1,371,334 1,403,271 1,054,321 854,293 890,468 890,468 
        committments
                                                                                
        deposits
                                                                110,000 76,000               
        legal contingency
                                                                                
      Cashflow Statements:
      Quarterly
      Annual
        Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 2014-06-30 2014-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31 2010-12-31 2010-09-30 2010-06-30 2010-03-31 2009-12-31 2009-09-30 2009-06-30 2009-03-31 2008-09-30 2008-06-30 2008-05-13 
                                                                                
          cash flows from operating activities
                                                                                
          net loss
        -17,106,000 -9,881,000 -27,129,000 -45,092,000 -25,923,000 -15,324,000 -17,699,000 -18,642,000 -27,061,000 -14,326,000 -18,516,000 -24,331,000 -30,795,000    -49,408,000    -22,114,000   -6,824,000 -6,978,000                                             -388,210 -193,085 -265,363 
          adjustments to reconcile net loss to net cash from operating activities:
                                                                                
          depreciation
        8,780,000 8,763,000 8,803,000 9,140,000 9,366,000 9,827,000 9,623,000 9,746,000 9,905,000 9,578,000 9,349,000 9,475,000 9,048,000 9,478,000 8,973,000 8,526,000 8,395,000 8,385,000 8,178,000 6,949,000 6,680,000 7,199,000 6,528,000 5,937,000 6,240,000 5,146,000 4,848,000 5,081,000 5,271,000 4,327,000 4,033,000 3,811,000 3,633,000 3,857,000 3,833,000 3,927,000 3,979,000 4,387,000 4,221,000 3,744,000 3,585,000                  521,000 475,000 488,000  459,000 423,000 415,000  310,849 265,943 237,059 512,913 323,720 156,416 
          amortization of intangibles
        7,633,000 7,632,000 7,634,000 8,124,000 8,362,000 8,361,000 8,362,000 8,361,000 8,362,000 8,783,000 8,784,000 8,783,000 8,783,000 8,588,000 8,491,000 8,489,000 8,490,000 8,477,000 8,474,000 3,751,000 2,458,000 2,430,000 2,468,000 2,467,000 2,452,000 2,443,000 2,380,000 2,543,000 2,559,000 1,673,000 1,421,000 1,421,000 1,413,000 1,794,000 1,751,000 1,725,000 1,725,000 1,818,000 1,818,000 1,610,000 2,026,000 129,000 93,000 97,000 93,000 95,000 89,000 55,000 56,000 55,000 57,000 55,000 56,000 56,000 56,000 56,000 14,000                
          stock-based compensation
        9,636,000 8,042,000 10,306,000 12,214,000 10,754,000 8,328,000 8,470,000                                                    129,000 156,000 93,000  114,000 117,000 109,000  124,735 112,694 58,000 229,539   
          non-cash operating lease expense
        1,720,000 1,713,000 1,686,000 1,769,000 1,584,000 1,904,000 2,229,000 2,392,000 2,401,000 2,375,000 2,212,000 2,318,000 2,330,000 2,400,000 2,386,000 2,336,000 2,653,000 2,549,000 2,417,000 1,888,000 1,862,000 -197,000 2,252,000 2,092,000 2,021,000 2,411,000                                               
          other adjustments
        402,000 -326,000 343,000 -377,000 37,000 37,000 -18,000 216,000 -57,000  -1,543,000 1,696,000 -31,000  -174,000 476,000 1,126,000                                                        
          changes in assets and liabilities
                                                                                
          accounts receivable
        -8,182,000 -4,207,000 -2,368,000 1,065,000 -668,000 888,000 -4,848,000 -6,301,000 -9,052,000 1,412,000 -7,215,000 -6,583,000 870,000 -7,717,000 -718,000 -480,000 1,334,000 -7,166,000 1,320,000 -2,766,000 3,921,000 -3,146,000 -15,953,000 12,220,000 -5,722,000 -3,082,000 -1,041,000 -7,383,000 -5,795,000                                            
          inventories
        -1,271,000 -28,000 5,632,000 -4,123,000 -3,024,000 -2,291,000 -1,243,000 -3,001,000 3,836,000 -202,000 636,000 -688,000 -200,000 -697,000 -1,936,000 1,978,000 -445,000 -1,562,000 -449,000 800,000 2,845,000 -9,493,000 984,000 -1,340,000 -5,348,000 -1,772,000 -3,899,000 936,000 -1,019,000              449,000 -821,000 21,000                            
          prepaid and other assets
        -1,395,000 3,205,000 -514,000 1,969,000 -3,105,000 -5,625,000 -1,522,000 2,292,000 -1,976,000 1,985,000 -2,551,000 -1,427,000 -1,187,000 2,445,000 -1,403,000 -158,000 -2,044,000 9,890,000 -7,115,000 -3,887,000 -794,000 -5,561,000 1,093,000                                                  
          operating lease liabilities
        -1,299,000 -1,233,000 -795,000 903,000 -1,090,000 -1,712,000 -979,000 -1,876,000 -1,432,000 -1,752,000 -2,577,000 -1,572,000 -1,722,000                                                            
          deferred income tax liabilities
        -769,000 -2,694,000 869,000 -993,000 -541,000 -1,556,000 -244,000 -475,000 -795,000 -1,813,000 -3,441,000 -2,904,000 -3,035,000                                                            
          accrued compensation
        -7,004,000 -4,098,000 2,773,000 8,617,000 -22,957,000 10,279,000 1,285,000 16,271,000 -18,552,000 5,567,000 1,908,000 12,795,000 -7,250,000                                                            
          accounts payable and other liabilities
        718,000  -5,823,000 6,575,000 1,143,000  5,037,000 -4,847,000 -138,000  -2,481,000 -4,610,000 4,101,000                              43,000 1,037,000 -1,078,000                            
          net cash from operating activities
        -8,137,000 1,343,000 8,884,000 20,330,000 -25,327,000 9,800,000 9,246,000 13,892,000 -25,915,000 17,784,000 -5,497,000 -1,548,000 -12,692,000 -3,685,000 -16,272,000 -16,996,000 -29,040,000 -19,776,000 -7,767,000 -1,390,000 2,210,000 5,985,000 526,000 1,882,000 -6,933,000 3,359,000 18,634,000 -4,721,000 6,097,000 15,453,000 8,381,000 6,640,000 14,312,000 5,759,000 7,436,000 6,528,000 -1,686,000 -241,000 9,623,000 5,036,000 7,059,000 2,121,000 2,375,000 2,684,000 -787,000 986,000 3,166,000 4,273,000 1,025,000 -505,000 2,199,000 1,863,000 -1,330,000   1,081,000 -1,065,000 1,239,000 -116,000 490,000 -1,544,000 361,000 -925,000 76,000 -1,564,000 -454,517 -513,322 -201,039 -331,539 -181,654 -521,601 194,638 
          capital expenditures
        -5,000,000 -7,871,000 -8,314,000 -6,323,000 -4,500,000 -11,599,000 -10,799,000 -13,078,000 -5,585,000 -7,057,000 -4,274,000 -7,494,000 -9,927,000 -4,534,000 -7,844,000 -10,294,000 -8,219,000 -11,987,000 -14,977,000 -21,347,000 -15,831,000 -11,505,000 -7,857,000 -5,026,000 -4,708,000 -6,076,000 -7,316,000 -3,441,000 -3,196,000 -3,219,000 -2,148,000 -4,277,000 -4,666,000 -3,523,000 -2,303,000 -4,857,000 -3,007,000 -2,208,000 -1,903,000 -2,424,000 -1,001,000 -533,000 -502,000 -338,000 -842,000 -1,053,000 -753,000 -1,083,000 -883,000 -525,000 -878,000 -369,000 -239,000   -760,000 -277,000 -559,000 -213,000 -54,000 -71,000 -103,000 -313,000 -386,000 -114,000 -531,558 -292,736 -133,560 -5,886 -370,218 -170,764 -25,115 
          free cash flows
        -13,137,000 -6,528,000 570,000 14,007,000 -29,827,000 -1,799,000 -1,553,000 814,000 -31,500,000 10,727,000 -9,771,000 -9,042,000 -22,619,000 -8,219,000 -24,116,000 -27,290,000 -37,259,000 -31,763,000 -22,744,000 -22,737,000 -13,621,000 -5,520,000 -7,331,000 -3,144,000 -11,641,000 -2,717,000 11,318,000 -8,162,000 2,901,000 12,234,000 6,233,000 2,363,000 9,646,000 2,236,000 5,133,000 1,671,000 -4,693,000 -2,449,000 7,720,000 2,612,000 6,058,000 1,588,000 1,873,000 2,346,000 -1,629,000 -67,000 2,413,000 3,190,000 142,000 -1,030,000 1,321,000 1,494,000 -1,569,000   321,000 -1,342,000 680,000 -329,000 436,000 -1,615,000 258,000 -1,238,000 -310,000 -1,678,000 -986,075 -806,058 -334,599 -337,425 -551,872 -692,365 169,523 
          cash flows from investing activities
                                                                                
          proceeds from maturities of marketable securities
         9,000,000 3,000,000 8,060,000 6,132,000 7,283,000 20,391,000 20,110,000 24,252,000                                                               
          purchases of property and equipment
        -5,000,000 -7,871,000 -8,314,000 -6,323,000 -4,500,000 -11,599,000 -10,799,000 -13,078,000 -5,585,000 -7,057,000 -4,274,000 -7,494,000 -9,927,000 -4,534,000 -7,844,000 -10,294,000 -8,219,000 -11,987,000 -14,977,000 -21,347,000 -15,831,000 -11,505,000 -7,857,000 -5,026,000 -4,708,000 -6,076,000 -7,316,000 -3,441,000 -3,196,000 -3,219,000 -2,148,000 -4,277,000 -4,666,000 -3,523,000 -2,303,000 -4,857,000 -3,007,000 -2,208,000 -1,903,000 -2,424,000 -1,001,000 -533,000 -502,000 -338,000 -842,000 -1,053,000 -753,000 -1,083,000 -883,000 -525,000 -878,000 -369,000 -239,000 -352,000 -1,226,000 -760,000 -277,000 -559,000 -213,000 -54,000 -71,000 -103,000 -313,000 -386,000 -114,000 -531,558 -292,736 -133,560 -5,886 -370,218 -170,764 -25,115 
          net cash from investing activities
        -5,000,000 -6,305,000 -277,000 -9,314,000 3,560,000 -5,467,000 -3,516,000 7,313,000 14,525,000 17,195,000 20,821,000 14,949,000 23,742,000 -1,063,000 -4,198,000 -6,274,000 12,052,000 -9,583,000 -14,686,000 -453,410,000 -154,688,000 -28,854,000 -70,716,000 -18,163,000 -41,708,000 -6,076,000 -7,316,000 -3,042,000 -3,196,000 -128,596,000 -2,148,000 -4,277,000 -4,666,000 -3,523,000 -2,303,000 -4,857,000 -3,007,000 -1,173,000 -1,903,000 -2,424,000 -1,001,000 -73,473,000 -502,000 -338,000 -842,000 -1,054,000 -6,582,000 -1,083,000 -883,000 -525,000 -878,000 -369,000 -239,000   -736,000 -1,314,000 -559,000 -213,000 -54,000 -71,000 -103,000 -313,000 -386,000 -114,000 -531,558 -292,736 -133,560 -5,886 -370,218 -170,764 -25,115 
          cash flows from financing activities
                                                                                
          issuance of common stock
        -338,000 431,000 765,000 -1,183,000 949,000 687,000 1,177,000 1,966,000 816,000 1,274,000 1,846,000 93,000 1,411,000 1,854,000 3,091,000 1,239,000 6,403,000 2,970,000 4,065,000 5,428,000 2,617,000 9,549,000 5,292,000 2,004,000 3,465,000 1,070,000 2,071,000 3,813,000 4,248,000 2,649,000 135,857,000 5,105,000 483,000                                        
          net cash from financing activities
        -338,000 431,000 765,000 -202,433,000 949,000 687,000 1,177,000 1,966,000 816,000 1,270,000 1,841,000 64,000 1,379,000 1,802,000 2,959,000 1,011,000 6,057,000 2,460,000 -6,720,000 204,610,000 524,935,000 8,265,000 4,115,000 222,600,000 617,000 -3,158,000 137,000 162,004,000 483,000 4,547,000 102,785,000 -8,124,000 -7,249,000 -1,670,000 -3,854,000 -1,775,000 3,204,000 -14,996,000 -571,000 -82,000 -10,222,000 60,806,000 -859,000 -642,000 -812,000 -609,000 32,759,000 -3,552,000 409,000 935,000 -1,028,000 -1,486,000 4,329,000 181,000 1,231,000 -535,000 2,507,000 -701,000 346,000 -337,000 3,051,000 -716,000 616,000 826,000 1,708,000 -510,903 3,236,383 175,131 726,444 972,664 923,979 -49,738 
          net change in cash and cash equivalents
        -13,475,000 -4,499,000 9,394,000 -191,471,000 -20,818,000 5,020,000 6,907,000 23,171,000 -10,574,000 36,249,000 17,165,000 13,465,000 12,429,000             -5,875,000 11,455,000 154,241,000 3,384,000  109,005,000 -5,738,000 2,352,000 610,000 1,279,000 -104,000 -1,489,000 -16,410,000 7,149,000 2,530,000 -4,164,000                                
          cash and cash equivalents, beginning of period
        159,618,000  367,012,000  342,488,000  263,180,000              9,811,000  12,821,000          33,689,000  4,834,000  1,868,000  2,628,000  1,097,000  1,631,000  468,171 210,573 210,573 210,573 
          cash and cash equivalents, end of period
        146,143,000  9,394,000 -191,471,000 346,194,000  6,907,000 23,171,000 331,914,000  17,165,000 13,465,000 275,609,000              11,455,000 154,241,000 13,195,000  109,005,000 -5,738,000 15,173,000  1,279,000 -104,000 11,036,000  7,149,000 2,530,000 19,256,000  1,014,000 1,704,000 31,248,000  29,343,000 -362,000 5,385,000  293,000 8,000 4,628,000  -528,000 -190,000 2,756,000  17,000 99,000 2,533,000  -622,000 516,000 1,661,000  2,430,325 -159,468 857,190 631,365 442,187 330,358 
          amortization of convertible debt discount
         374,000 372,000 477,000 687,000 684,000 683,000 680,000 678,000 676,000 674,000 672,000 669,000 668,000 665,000 663,000 661,000 659,000 657,000 654,000 593,000 1,653,000 1,841,000                                                  
          amortization of debt issuance costs
                 46,000                                                               
          loss on disposal of assets
             -112,000    -42,000    -208,000         108,000 246,000 17,000 21,000 47,000 248,000 156,000  172,000                                          
          impairment charges
         626,000 7,086,000                                                                      
          impairment of long-lived assets
                                                                                
          changes in assets and liabilities, net:
                                                                                
          accounts payable, accrued and other liabilities
                          10,673,000 11,178,000 -6,538,000 5,365,000 1,840,000 -12,366,000 1,191,000 -11,471,000 8,916,000 -10,880,000 4,434,000                                            
          purchases of marketable securities
                 -6,756,000 -23,632,000 -17,641,000 -40,165,000 -16,167,000 -15,830,000 -18,192,000 -24,993,000 -137,776,000 -19,705,000                                                   
          proceeds from assets held for sale, net of closing costs
                                                                                
          business acquisitions, net of cash acquired
                                                                              
          purchase of convertible note
                                                                                
          purchase of equity securities
                                                                                
          repayment of equipment financing obligations
                 -4,000 -5,000 -29,000 -32,000 -52,000 -132,000 -228,000 -346,000 -510,000 -645,000 -801,000 -1,091,000 -1,284,000 -1,272,000 -1,461,000 -1,598,000                                                
          repayment of convertible debt
                                                                              
          cash, cash equivalents and restricted cash, beginning of year
                                                                                
          cash, cash equivalents and restricted cash, end of year
                                                                                
          amortization of debt issue costs
          9,000 21,000 48,000  47,000 47,000 47,000   46,000 46,000  45,000 46,000 45,000  45,000 45,000 43,000  26,000 42,000 70,000 67,000 73,000 100,000 150,000 150,000 150,000 129,000 113,000 110,000 111,000 109,000 110,000 2,965,000 174,000 176,000 182,000     41,000 13,000 12,000 13,000 12,000 12,000 12,000 9,000 10,000 10,000 9,000 10,000 9,000 10,000 11,000 11,000 10,000 10,000 18,000 22,095 16,654 16,655 13,245 35,321 22,076 8,830 
          other impairment charges
                                                                                
          purchases of equity securities
                                                                                
          business acquisition, net of cash acquired
          -463,000                                                                      
          net change in cash and cash equivalents, including cash classified within current assets held for sale
          9,372,000                                                                      
          less: net change in cash classified within current assets held for sale
          22,000                                                                      
          impairment of assets
             117,000 188,000 145,000    923,000                                                            
          gain on sale of assets held for sale
                     -2,048,000                                                        
          proceeds from assets held for sale
                                                                              
          non-cash stock-based compensation
                7,774,000 6,990,000 7,180,000 5,705,000 4,758,000 4,663,000 4,280,000 3,626,000 12,103,000 10,062,000 5,237,000 4,506,000 2,653,000 2,676,000 2,715,000 2,635,000 2,186,000                                                
          gain on investment in and loan receivable from non-consolidated affiliate
                         -17,750,000                                                      
          interest on loan receivable from non-consolidated affiliate
                                                                                
          write off of covid-19 pcr testing inventory and equipment
                                                                                
          other non-cash items
                         1,159,000 598,000 242,000 548,000                                                    
          prepaid lease asset
                         -353,000 295,000 -3,907,000 -823,000 -10,087,000 -4,058,000 -2,768,000 -3,316,000                                                
          loan receivable from non-consolidated affiliate
                         -15,000,000                                                    
          proceeds from issuance of convertible debt, net of issuance costs
                         334,410,000 90,000                                                  
          premiums paid for capped call transactions
                                                                                
          proceeds from equity offering, net of issuance costs
                            218,290,000 5,000                                                  
          proceeds from sales and maturities of marketable securities
                   22,443,000 40,425,000 27,103,000 21,287,000 32,087,000 36,438,000 18,234,000 18,483,000 12,334,000 13,919,000                                                    
          net income
                     -22,687,000 -36,852,000   -41,759,000 -20,347,000   15,417,000    6,296,000 2,143,000 1,991,000 -2,424,000 353,000 2,023,000 -380,000 644,000  -5,100,000 -43,000 -654,000 -6,223,000 -68,000 413,000 155,000 -1,473,000 -125,000 -176,000 -761,000 1,047,000 -291,000 274,000 102,000 857,000 900,000 273,000 3,000 -113,000 -976,000 551,000 603,000    -893,000   -978,000 -750,000  -755,306 8,060 33,178    
          adjustments to reconcile net income to net cash from operating activities:
                                                                                
          loss on debt extinguishment
                                                                            
          loss on termination of cash flow hedge
                                                                              
          investment in non-consolidated affiliate
                             -12,463,000                                                  
          repayment of term loan
                             -96,290,000 -1,250,000 -2,500,000 -94,782,000 -1,968,000 -1,313,000        -54,587,000                                   
          cash flow hedge termination
                                                                              
          cash, cash equivalents and restricted stock, beginning of year
                                                                                
          interest receivable on loan receivable from non-consolidated affiliate
                          -182,000 -209,000                                                    
          write-off of covid-19 pcr testing inventory and equipment
                          6,061,000                                                    
          accounts payable, operating lease liabilities, deferred taxes, accrued and other liabilities
                      -3,095,000 -7,195,000 -9,902,000                                                        
          premiums paid for capped call confirmations
                          -29,291,000                                                    
          net change in cash, cash equivalents and restricted cash
                      -17,511,000 -22,259,000 -10,931,000  -29,173,000 -250,190,000 372,457,000  -66,075,000 206,319,000 -48,024,000                                                
          cash, cash equivalents and restricted cash, beginning of period
                      316,827,000  250,632,000  173,016,000                                                
          cash, cash equivalents and restricted cash, end of period
                      -17,511,000 -22,259,000 305,896,000  -29,173,000 -250,190,000 623,089,000  -66,075,000 206,319,000 124,992,000                                                
          unrealized loss on investment in non-consolidated affiliate
                            5,024,000                                                    
          acquisition working capital adjustment
                                                                                
          repayment of revolving credit facility
                                            -10,044,000                                
          proceeds from term loan
                                                                            
          payments of debt issuance costs for term loan
                                                                                
          cash and cash equivalents, beginning of year
                                                                                
          proceeds from equity offerings, net of issuance costs
                          -10,140,000                                                      
          business acquisition
                             -37,000,000                                                
          unrealized gain on investment in non-consolidated affiliate
                                                                                
          advances on revolving credit facility
                                                                                
          redemption of preferred stock
                                                                              
          effects of foreign exchange rate changes on cash and cash equivalents
                                     -33,000 -13,000 23,000 -45,000                                        
          other current assets
                              -1,875,000 -677,000 -16,000  1,516,000 -1,632,000 -265,000              -268,000 -99,000 -42,000                            
          proceeds from sale of marketable securities
                                                                                
          payments of debt issuance costs
                                                                                
          prepaid assets
                                270,000 779,000 -630,000                                              
          reconciliation of cash, cash equivalents and restricted cash to the consolidated balance sheets:
                                                                                
          cash and cash equivalents
                                86,254,000                                                
          restricted cash, non-current
                                38,738,000                                                
          total cash, cash equivalents and restricted cash
                                124,992,000                                                
          supplemental disclosure of cash flow information:
                                                                                
          interest paid
                                1,136,000  1,117,000 1,482,000 1,696,000 1,789,000 2,019,000 1,307,000 1,396,000 1,276,000 1,306,000 1,316,000 1,257,000 1,430,000 1,302,000 1,275,000 1,416,000 239,000 255,000 205,000 212,000 211,000 272,000 244,000 254,000 358,000 220,000 221,000 274,000 299,000 280,000 279,000 250,000 216,000 175,000 170,000 174,000 177,000 171,000 169,000 144,000 128,500 120,984 113,867 100,391 171,606 107,820 47,931 
          income taxes paid
                                2,000   227,000 8,000   42,000 7,000 12,000 170,000 97,000 5,000 62,000 6,000 15,000 207,000 5,000 15,000 5,000 7,000 11,000 159,000 -2,000 2,000 17,000         2,000 7,000          
          supplemental disclosure of non-cash investing and financing information:
                                                                                
          equipment acquired under financing obligations
                                                                                
          property and equipment included in accounts payable
                                1,844,000  -160,000 -205,000 1,175,000                                            
          loss on sale of business
                                                                                
          non-cash stock based compensation
                                 2,273,000 3,275,000 2,313,000 2,139,000  1,191,000 2,333,000 1,624,000                                        
          other assets
                                                  -1,000 12,000 1,000                            
          acquisition, net of cash acquired
                                                     -1,000                           
          repayment of equipment and other loans
                                 -1,720,000 -1,837,000 -1,847,000 -1,797,000                                            
          payments of debt issue costs
                                 -8,000 -97,000                                            
          proceeds from equity offering
                                                                              
          cash and cash equivalent, beginning of year
                                                                                
          cash and cash equivalents, end of year
                                                                                
          acquisition adjustment
                                                                                
          cash paid for operating lease liabilities
                                  1,015,000                                              
          income taxes paid (refunded)
                                     45,000                                           
          working capital adjustment related to acquisition
                                                                               
          equipment acquired under loan obligations
                                  963,000 699,000 2,003,000                                            
          non-cash operating lease expenses
                                   1,077,000 1,141,000                                            
          prepaid expenses
                                    -250,000                                            
          adjustments to reconcile net income to net cash fromoperating activities, net of business acquisition:
                                                                                
          impairment/loss on sale of assets
                                                                                
          loss on extinguishment of debt
                                                                                
          stock based compensation
                                                                              124,539 48,537 
          changes in assets and liabilities, net of business acquisition:
                                                                                
          decrease in accounts receivable, net of write-offs
                                        2,299,000              1,972,000 -468,000 -1,492,000 -3,757,000 -299,000 -1,025,000 -2,335,000 -2,640,000 -1,384,000 -1,540,000 -3,628,000 -1,356,000 -842,000 -1,478,000 -1,550,000            
          decrease in inventories
                                     90,000 68,000 617,000 -41,000   513,000 283,000    -225,000      -267,000 -613,000 298,000 -233,000 -330,000 -93,000 214,000 47,000 -380,000 -215,000 -109,000 -107,000 -16,000 -168,000 -24,000            
          decrease in other assets
                                                     2,000 1,000   24,000 -8,000   8,000                   
          decrease in other current assets
                                        -158,000    6,000 400,000        -118,000 59,000 -133,000 167,000 -612,000 -332,000 47,000 -35,000 35,000 55,000   -341,000 -54,000              
          increase in accounts payable and other liabilities
                                         -6,910,000 5,163,000 -2,059,000 -738,000 -5,374,000 -205,000       636,000 -664,000 2,731,000 -237,000 844,000 673,000 770,000 -1,419,000 794,000 170,000 179,000 300,000    -666,000            
          (payments) advances from revolving credit facility
                                                                                
          repayment of capital lease obligations
                                                 -1,203,000 -1,079,000                              
          net increase in cash and cash equivalents
                                                  1,014,000 1,704,000 -2,441,000  29,343,000 -362,000 551,000  293,000 8,000 2,760,000  -528,000 -190,000 128,000  17,000 99,000 1,436,000  -622,000 516,000 30,000  2,430,325 -159,468 389,019 420,792 231,614 119,785 
          equipment acquired under capital lease/loan obligations
                                     3,836,000 378,000 3,355,000 2,488,000 683,000 659,000 1,898,000 1,150,000 2,322,000 2,412,000 173,000                                
          purchases of property and equipment included in accounts payable
                                                                                
          fair value of common stock issued to fund acquisition
                                                                                
          fair value of restricted stock issued to fund purchase of customer list
                                                                                
          loss on sale of path logic
                                                                                
          (increase) in accounts receivable, net of write-offs
                                      -1,929,000   -3,327,000 -6,651,000 -4,276,000 -9,989,000 -9,001,000 580,000 -6,195,000 -3,809,000                                
          (increase) in prepaid expenses
                                      1,639,000 -208,000 -1,990,000  314,000 601,000 -1,321,000  -880,000                                  
          (increase) in other current assets
                                      -772,000    31,000                                      
          increase in accounts payable, accrued and other liabilities
                                      385,000 2,260,000 6,782,000                                        
          repayment of capital lease obligations, loans
                                      -1,760,000 -1,620,000 -1,394,000                                        
          purchase of customer list through issuance of restricted stock
                                                                                
          advances from revolving credit facility
                                         -2,501,000 -9,000 5,006,000                                    
          repayment of term loan and revolving credit facility
                                       -937,000 -6,338,000                                        
          gain on sale of assets
                                        -7,000                                        
          payments of equity issue costs
                                          -85,000 -112,000                                    
          net
                                                                  -143,000              
          adjustments to reconcile net (loss) to net cash provided by operating activities, net of business acquisition:
                                                                                
          impact of tax valuation allowance
                                                                                
          provision for bad debts
                                         5,623,000 4,999,000 4,244,000 3,783,000 3,673,000 2,749,000 2,771,000 2,663,000     393,000 230,000 930,000 884,000 831,000 579,000 646,000 741,000 619,000 699,000 896,000 839,000 827,000 631,000 515,000 594,000 508,000 580,000 626,000 540,000 795,823 424,266 426,737 507,741 1,095,387 815,011 425,453 
          (increase) in inventories
                                         -1,386,000    -301,000 -407,000                                  
          acquisition, net of cash acquired of 0, 0 and 890
                                                                                
          issuance of common stock for the exercise of options, warrants and espp shares, net of transaction expenses
                                                1,201,000                                
          fair value of preferred stock issued to fund acquisition
                                                                                
          stock based compensation – options, restricted stock and warrants
                                          2,760,000 1,922,000 1,130,000  1,687,000 1,634,000 703,000                                
          repayment to revolving credit facility
                                                                                
          repayment of capital lease obligations/loans
                                          -1,372,000 -1,491,000 -1,263,000  -1,263,000 -1,232,000 -1,379,000                                
          repayment on term loan
                                          -938,000 -946,000 -932,000                                    
          proceeds from the exercise of options, warrants and espp shares, net of transaction expenses
                                          1,042,000    1,105,000                                  
          cash and cash equivalent, beginning of period
                                          12,525,000  23,420,000                                
          deemed dividends on preferred stock
                                          912,000 928,000 894,000  1,840,000                                  
          amortization of preferred stock beneficial conversion feature
                                          1,739,000 1,711,000 1,672,000  3,727,000                                  
          issuance of common stock for the exercise of options, warrants and espp shares
                                            505,000      220,000 270,000 109,000                            
          adjustments to reconcile net income to net cash provided by operating activities, net of business acquisition:
                                                                                
          stock based compensation – options and restricted stock
                                                 1,301,000                               
          stock based compensation – warrants
                                                 271,000                               
          acquisition, net of cash acquired of 0, 890 and 79
                                                                                
          advances from (repayments to) revolving credit facility
                                                                                
          issuance of common stock for cash , net of transaction expenses
                                                                                
          adjustments to reconcile net income to net cash from operating activities, net of business acquisition:
                                                                                
          decrease in prepaid expenses
                                                -401,000               91,000 7,000    389,000            
          (decrease) in accounts payable and other liabilities
                                                2,180,000                                
          acquisition, net of cash acquired of 890 and 79
                                                                                
          bad debt expense
                                                  546,000 701,000 602,000                            
          depreciation and amortization of property and equipment
                                                  1,722,000 1,663,000 1,586,000                            
          accounts receivable, net of write-offs
                                                  -972,000 -348,000 -1,610,000                            
          acquisition, net of cash
                                                                                
          payments on credit facility
                                                                                
          issuance of common stock for cash, net of transaction expense
                                                                                
          supplemental disclosure of cash flow information
                                                                                
          non-cash investing and financing activities
                                                                                
          equipment leased under capital lease obligations and equipment loans
                                                                                
          stock-based compensation – options and restricted stock
                                                   471,000 342,000                            
          stock-based compensation – warrants
                                                   148,000 59,000                            
          equipment leased under capital lease obligations
                                                   875,000 2,525,000                            
          repayments of capital lease obligations
                                                    -921,000                            
          purchases of intangible assets
                                                                                
          (repayments to) advances from revolving credit facility
                                                                                
          restricted cash
                                                             300,000 200,000                
          common stock issued for intangible asset purchase
                                                                               
          depreciation of property and equipment
                                                      1,538,000 1,249,000 1,151,000 1,074,000 1,063,000 1,062,000 990,000  944,000 856,000 749,000                
          stock-based compensation – options
                                                      320,000 157,000 89,000  9,000 130,000 254,000  230,000 153,000 105,000                
          stock-based compensation – warrants and restricted stock
                                                      138,000 40,000 -5,000  -125,000 73,000 189,000  127,000 38,000 46,000                
          advances (payments) on credit facility
                                                      -1,990,000    -458,000    1,642,000                  
          repayment of capital leases and loans
                                                                  -393,000    -361,000          
          issuance of common stock for the exercise of stock options and warrants
                                                                                
          issuance of common stock for cash, net of transaction expenses
                                                                                
          equipment leased under capital leases
                                                      1,503,000 1,628,000 1,693,000 1,433,000 414,000 1,021,000 381,000 -63,000 705,000 966,000 1,174,000 1,587,000 732,000 382,000 141,000 255,000 316,000 357,000 746,000 713,290 378,271 507,086 178,837    
          repayment of capital leases
                                                          -674,000    -533,000 -549,000 -555,000    -377,000    -300,000  -216,993 -187,157 -137,938 -244,612 -139,905 -63,208 
          issuance of common stock and warrants for cash, net of transaction expenses
                                                          104,000   8,000 122,000 307,000 74,000    3,018,000  35,000 34,000 82,000  5,311,562 -76,865 495,309 41,055 10,413 13,470 
          advances (repayments) on credit facility
                                                        583,000    -4,268,000                    
          repayments of capital leases and loans
                                                        -772,000                        
          issuance of common stock and warrants for cash, net of transaction costs
                                                        598,000    9,167,000                    
          stock based compensation – options
                                                                                
          stock based compensation – warrants and restricted stock
                                                                                
          advances (repayments) from/to revolving credit facility
                                                                                
          issuance of common stock and warrants for cash , net of transaction expenses
                                                                                
          purchase of intangible assets
                                                              -24,000 24,000 -1,037,000                
          non-cash intangible asset purchase
                                                               1,945,000                
          repayments of capital leases
                                                            -570,000                    
          net cash (used) in operating activities
                                                                                
          net cash (used) in investing activities
                                                                                
          advances on credit facility
                                                                2,788,000  653,000 -33,000 410,000  943,000 504,000 1,901,000  -1,858,186      
          depreciation and amortization
                                                                                
          proceeds from issuance of capital lease on owned assets
                                                                                
          automobiles purchased under a car loan
                                                                                
          adjustments to reconcile net (loss) to net cash from operating activities:
                                                                                
          decrease in deposits
                                                                  -35,000 17,000 -19,000            
          increase in accounts payable, accrued expenses and other liabilities
                                                                  -316,000              
          proceeds from capital lease obligations
                                                                      -1,000 122,000 25,000  96,890    
          decrease in restricted cash
                                                                               
          issuance of common stock, net of transaction costs
                                                                  86,000              
          adjustments to reconcile net income to net cash from provided by operating activities:
                                                                                
          non-cash consulting expenses
                                                                    33,000 36,000 41,000 108,000 19,000 18,696 18,696 10,622 19,724 99,813   
          common stock issued for the purchase of assets
                                                                                
          (increase) decrease in accounts receivable, net of write-offs
                                                                      -825,000 -518,000 -1,401,000   -642,834 -1,549,476 -1,239,702 -1,220,083 -126,607 
          (increase) decrease in inventories
                                                                      39,000 -225,000 20,000   -20,882 -86,271 -39,857 -59,508 58,764 
          (increase) decrease in prepaid expenses
                                                                      1,000 -148,000 122,000        
          (increase) decrease in deposits
                                                                           -15,492 -8,282 -14,512 5,009  
          increase (decrease) in accounts payable and other liabilities
                                                                      -148,000 663,000 -656,000   -207,774 471,539 -79,447 -38,205 -122,462 
          equipment purchased and included in accounts payable
                                                                                
          equipment purchased and payables settled with issuance of restricted common stock
                                                                          186,000    
          loss on investments
                                                                                
          other non-cash expenses
                                                                                
          (increase) decrease in other current assets
                                                                              -368,117 -35,402 
          increase (decrease) in legal contingency
                                                                                
          decrease in pre-paid expenses
                                                                                
          equipment purchased and included in accounts payable at september 30
                                                                                
          (increase) decrease in pre-paid expenses
                                                                           -154,768 -27,996 -405,841   
          equipment purchased and included in accounts payable at june 30
                                                                                
          advances / (repayments) on credit facility
                                                                            272,183 1,176,221 1,053,471  
          equipment purchased and included in accounts payable at march 31
                                                                            46,250    
          amortization of credit facility warrants and debt issue costs
                                                                                
          investment in other assets
                                                                                
          advances (repayments) from/to affiliates
                                                                                
          notes payable
                                                                                
          amortization of lease cap costs
                                                                             4,080   
          amortization of relocation costs
                                                                             8,862   
          amortization of credit facility warrants
                                                                                
          purchase of convertible debenture
                                                                                
          advances / (repayments) to affiliates
                                                                                
          repayment of notes payable
                                                                                
          equipment leased under capital leases, including 140,000 in accrued expenses at december 31, 2007
                                                                             538,761 234,833 162,043 
          equipment purchased and included in accounts payable at september 30, 2008
                                                                             126,227   
          non cash consulting expenses
                                                                              67,042 34,271 
          equipment purchased and included in accounts payable at june 30, 2008
                                                                              165,653  
          increase (decrease) in deposits
                                                                               12,201 
          advances from/(repayments to) affiliates
                                                                                
          equipment purchased and included in accounts payable at march 31, 2008
                                                                               33,713 
          benefit from bad debts
                                                                                
          increase in accounts receivable, net of write-offs
                                                                                
          increase in inventories
                                                                                
          increase in other current assets
                                                                                
          increase in deposits
                                                                                
          net cash provided by/(used in) operating activities
                                                                                
          net cash provided by/(used in) financing activities