Lyell Immunopharma Inc(NASDAQ:LYEL) 
Lyell Immunopharma is an operator of a biotechnology company that develops cellular therapies to cure cancer. South San Francisco, California, United States.
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At a glance:
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Income Statements:
Quarterly
Annual
| Unit: USD | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
revenue | 6,000 | 15,000 | 8,000 | 7,000 | 11,000 | 34,000 | 13,000 | 3,000 | 13,000 | 25,000 | 27,000 | 65,000 | 48,386,000 | 3,000 | 35,741,000 | 553,000 | 2,822,000 | 2,755,000 | 2,628,000 |
yoy | -45.45% | -55.88% | -38.46% | 133.33% | -15.38% | 36.00% | -51.85% | -95.38% | -99.97% | 733.33% | -99.92% | -88.25% | 1614.60% | -99.89% | 1260.01% | ||||
qoq | -60.00% | 87.50% | 14.29% | -36.36% | -67.65% | 161.54% | 333.33% | -76.92% | -48.00% | -7.41% | -58.46% | -99.87% | 1612766.67% | -99.99% | 6363.11% | -80.40% | 2.43% | 4.83% | |
operating expenses: | |||||||||||||||||||
research and development | 52,199,000 | 28,172,000 | 34,857,000 | 43,447,000 | 48,668,000 | 39,500,000 | 40,261,000 | 43,174,000 | 46,995,000 | 43,849,000 | 47,471,000 | 44,630,000 | 38,032,000 | 41,607,000 | 43,719,000 | 35,830,000 | 19,285,000 | 31,433,000 | 46,446,000 |
general and administrative | 10,616,000 | 10,687,000 | 9,786,000 | 14,046,000 | 14,522,000 | 11,769,000 | 12,256,000 | 13,494,000 | 13,167,000 | 15,507,000 | 19,030,000 | 19,279,000 | 26,348,000 | 26,084,000 | 30,454,000 | 34,421,000 | 31,873,000 | 21,241,000 | 19,112,000 |
other operating income | -1,497,000 | -1,591,000 | -119,000 | -513,000 | -730,000 | -976,000 | -1,090,000 | -641,000 | -292,000 | -569,000 | -1,288,000 | -1,210,000 | -1,251,000 | -1,171,000 | -1,122,000 | -798,000 | -758,000 | -223,000 | |
impairment of long-lived assets | 1,443,000 | ||||||||||||||||||
total operating expenses | 127,650,000 | 37,268,000 | 47,148,000 | 57,374,000 | 201,158,000 | 50,539,000 | 51,541,000 | 55,578,000 | 59,521,000 | 59,064,000 | 65,932,000 | 62,621,000 | 63,170,000 | 66,440,000 | 73,002,000 | 69,129,000 | 50,360,000 | 51,916,000 | 65,335,000 |
income from operations | -127,644,000 | -37,253,000 | -47,140,000 | -57,367,000 | -201,147,000 | -50,505,000 | -51,528,000 | -55,575,000 | -59,508,000 | -59,039,000 | -65,905,000 | -62,556,000 | -14,784,000 | -66,437,000 | -37,261,000 | -68,576,000 | -47,538,000 | -49,161,000 | -62,707,000 |
yoy | -36.54% | -26.24% | -8.52% | 3.22% | 238.02% | -14.45% | -21.81% | -11.16% | 302.52% | -11.14% | 76.87% | -8.78% | -68.90% | 35.14% | -40.58% | ||||
qoq | 242.64% | -20.97% | -17.83% | -71.48% | 298.27% | -1.99% | -7.28% | -6.61% | 0.79% | -10.42% | 5.35% | 323.13% | -77.75% | 78.30% | -45.66% | 44.26% | -3.30% | -21.60% | |
operating margin % | -2127400.00% | -248353.33% | -589250.00% | -819528.57% | -1828609.09% | -148544.12% | -396369.23% | -1852500.00% | -457753.85% | -236156.00% | -244092.59% | -96240.00% | -30.55% | -2214566.67% | -104.25% | -12400.72% | -1684.55% | -1784.43% | -2386.11% |
interest income | 2,676,000 | 3,266,000 | 3,276,000 | 3,862,000 | 4,920,000 | 5,965,000 | 6,364,000 | 6,819,000 | 7,084,000 | 6,608,000 | 5,264,000 | 4,497,000 | 3,453,000 | 2,251,000 | 952,000 | 397,000 | 323,000 | 270,000 | 218,000 |
other income | -15,755,000 | -4,859,000 | 1,180,000 | 1,310,000 | 4,292,000 | -43,000 | -645,000 | 1,090,000 | -506,000 | 1,578,000 | -326,000 | 1,100,000 | 2,934,000 | -1,068,000 | -14,000 | 35,000 | -44,000 | 16,000 | -106,000 |
impairment of other investments | -13,001,000 | -2,923,000 | -10,000,000 | -5,000,000 | |||||||||||||||
total other income | -13,079,000 | -1,593,000 | 4,456,000 | 5,172,000 | 9,212,000 | 5,922,000 | 5,719,000 | 6,578,000 | 8,186,000 | 2,015,000 | -4,403,000 | 6,387,000 | -3,817,000 | 938,000 | 432,000 | ||||
net income | -140,723,000 | -38,846,000 | -42,684,000 | -52,195,000 | -191,935,000 | -44,583,000 | -45,809,000 | -60,667,000 | -52,930,000 | -50,853,000 | -63,890,000 | -66,959,000 | -8,397,000 | -70,254,000 | -36,323,000 | -68,144,000 | -83,706,000 | -48,875,000 | -62,595,000 |
yoy | -26.68% | -12.87% | -6.82% | -13.96% | 262.62% | -12.33% | -28.30% | -9.40% | 530.34% | -27.62% | 75.89% | -1.74% | -89.97% | 43.74% | -41.97% | ||||
qoq | 262.26% | -8.99% | -18.22% | -72.81% | 330.51% | -2.68% | -24.49% | 14.62% | 4.08% | -20.41% | -4.58% | 697.42% | -88.05% | 93.41% | -46.70% | -18.59% | 71.27% | -21.92% | |
net income margin % | -2345383.33% | -258973.33% | -533550.00% | -745642.86% | -1744863.64% | -131126.47% | -352376.92% | -2022233.33% | -407153.85% | -203412.00% | -236629.63% | -103013.85% | -17.35% | -2341800.00% | -101.63% | -12322.60% | -2966.19% | -1774.05% | -2381.85% |
other comprehensive loss: | |||||||||||||||||||
net unrealized gain on marketable securities | 41,000 | 144,000 | -101,000 | -469,000 | 1,157,000 | 7,000 | -310,000 | 1,087,000 | 1,198,000 | 1,500,000 | 3,720,000 | -1,558,000 | -138,000 | -90,000 | |||||
comprehensive loss | -140,682,000 | -38,702,000 | -42,785,000 | -52,328,000 | -192,404,000 | -43,426,000 | -45,802,000 | -60,977,000 | -51,843,000 | -49,655,000 | -62,390,000 | -63,239,000 | -6,000,000 | -71,899,000 | -38,074,000 | -73,121,000 | |||
net loss per common share, basic and diluted1 | -7,680 | -2,130 | -2,890 | ||||||||||||||||
weighted-average shares used for eps calculation | 17,093,000 | 18,268,000 | 14,793,000 | 295,098,000 | 261,480,000 | 256,309,000 | 255,398,000 | 254,252,000 | 250,983,000 | 251,318,000 | 250,204,000 | 249,591,000 | 247,080,000 | 248,320,000 | 246,312,000 | 244,178,000 | 135,918,000 | 239,384,000 | 42,713,000 |
other operating loss | 1,062,000 | ||||||||||||||||||
net unrealized loss on marketable securities | -133,000 | 2,397,000 | -1,645,000 | -1,751,000 | -4,977,000 | ||||||||||||||
net loss per common share, basic and diluted | -180 | -720 | -170 | -180 | -240 | -200 | -200 | -260 | -270 | -30 | -280 | -150 | -280 | -180 | -200 | -1,470 | |||
total other loss | -5,092,000 | ||||||||||||||||||
comprehensive loss: | |||||||||||||||||||
operating expenses | |||||||||||||||||||
other comprehensive gain: | |||||||||||||||||||
net comprehensive loss | -41,708,500 | -49,013,000 | -62,685,000 | ||||||||||||||||
net loss attributed to common stockholders: | |||||||||||||||||||
deemed dividends upon repurchase of convertible preferred stock | |||||||||||||||||||
net loss attributed to common stockholders | -83,706,000 | -48,875,000 | -62,595,000 |
Balance Sheets:
Quarterly
Annual
| Unit: USD | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
assets | |||||||||||||||||||
current assets: | |||||||||||||||||||
cash and cash equivalents | 60,181,000 | 123,575,000 | 98,804,000 | 120,328,000 | 105,597,000 | 100,299,000 | 133,424,000 | 125,650,000 | 145,647,000 | 286,214,000 | 224,372,000 | 109,426,000 | 123,554,000 | 116,311,000 | 205,739,000 | 222,596,000 | 293,828,000 | 393,504,000 | 564,441,000 |
marketable securities | 187,039,000 | 196,049,000 | 177,986,000 | 180,849,000 | 264,930,000 | 340,248,000 | 357,695,000 | 400,650,000 | 400,576,000 | 289,217,000 | 371,376,000 | 503,343,000 | 516,598,000 | 531,821,000 | 449,825,000 | 391,316,000 | 320,966,000 | ||
prepaid expenses and other current assets | 13,719,000 | 8,577,000 | 5,424,000 | 8,001,000 | 9,067,000 | 9,498,000 | 8,705,000 | 7,865,000 | 8,463,000 | 11,423,000 | 10,662,000 | 11,629,000 | 11,143,000 | 11,613,000 | 11,214,000 | 11,793,000 | 11,492,000 | 12,226,000 | 10,317,000 |
total current assets | 260,939,000 | 328,201,000 | 282,214,000 | 309,178,000 | 379,594,000 | 450,045,000 | 499,824,000 | 534,165,000 | 554,686,000 | 586,854,000 | 606,410,000 | 624,398,000 | 651,295,000 | 659,745,000 | 666,778,000 | 625,705,000 | 626,286,000 | 631,147,000 | 834,840,000 |
restricted cash | 1,585,000 | 1,585,000 | 1,584,000 | 1,688,000 | 1,690,000 | 288,000 | 287,000 | 286,000 | 284,000 | 283,000 | 282,000 | 281,000 | 280,000 | 279,000 | 279,000 | 279,000 | 466,000 | 466,000 | 466,000 |
marketable securities, non-current | 20,059,000 | 28,949,000 | 13,014,000 | 20,112,000 | 16,506,000 | 22,729,000 | 36,952,000 | 55,255,000 | 70,117,000 | 102,519,000 | 131,438,000 | 224,118,000 | 283,531,000 | ||||||
other investments | 19,000,000 | 19,000,000 | 19,000,000 | 19,000,000 | 19,000,000 | 19,000,000 | 19,000,000 | 19,000,000 | 32,001,000 | 32,001,000 | 32,001,000 | 34,924,000 | 44,924,000 | 42,001,000 | 47,001,000 | 47,001,000 | 47,001,000 | 83,448,000 | 83,448,000 |
property and equipment | 34,771,000 | 36,722,000 | 39,115,000 | 44,195,000 | 48,200,000 | 88,047,000 | 93,096,000 | 97,836,000 | 102,654,000 | 108,096,000 | 113,677,000 | 118,600,000 | 123,023,000 | 125,727,000 | 127,559,000 | 125,707,000 | 120,098,000 | 115,857,000 | 109,637,000 |
operating lease right-of-use assets | 18,871,000 | 19,912,000 | 20,951,000 | 23,570,000 | 24,739,000 | 36,662,000 | 37,696,000 | 38,695,000 | 39,663,000 | 40,603,000 | 41,512,000 | 42,390,000 | 43,242,000 | 44,084,000 | 44,907,000 | 45,725,000 | 46,541,000 | ||
other non-current assets | 4,886,000 | 2,545,000 | 2,530,000 | 3,218,000 | 4,622,000 | 5,061,000 | 4,239,000 | 4,238,000 | 4,235,000 | 4,423,000 | 4,520,000 | 4,602,000 | 4,680,000 | 2,914,000 | 3,712,000 | 3,568,000 | 3,483,000 | 2,669,000 | 2,791,000 |
total assets | 340,052,000 | 407,965,000 | 385,453,000 | 429,798,000 | 490,859,000 | 619,215,000 | 654,142,000 | 694,220,000 | 750,029,000 | 794,989,000 | 835,354,000 | 880,450,000 | 937,561,000 | 977,269,000 | 1,021,674,000 | 1,072,103,000 | 1,127,406,000 | 1,198,334,000 | 1,229,867,000 |
liabilities and stockholders’ equity | |||||||||||||||||||
current liabilities: | |||||||||||||||||||
accounts payable | 2,893,000 | 2,568,000 | 3,379,000 | 3,728,000 | 5,366,000 | 3,596,000 | 4,199,000 | 4,895,000 | 4,817,000 | 4,365,000 | 5,805,000 | 5,733,000 | 3,917,000 | 4,795,000 | 4,247,000 | 6,510,000 | 3,207,000 | 3,526,000 | 4,863,000 |
accrued liabilities and other current liabilities | 46,519,000 | 29,310,000 | 27,999,000 | 31,168,000 | 40,411,000 | 29,009,000 | 25,670,000 | 24,914,000 | 28,126,000 | 29,652,000 | 24,832,000 | 22,416,000 | 28,755,000 | 23,568,000 | 21,396,000 | 22,686,000 | 29,057,000 | 25,058,000 | 25,568,000 |
contingent consideration payable | 5,525,000 | 6,389,000 | 7,600,000 | ||||||||||||||||
total current liabilities | 49,412,000 | 31,878,000 | 36,903,000 | 41,285,000 | 53,788,000 | 33,512,000 | 30,879,000 | 32,353,000 | 34,519,000 | 35,064,000 | 34,390,000 | 30,797,000 | 37,028,000 | 51,217,000 | 50,291,000 | 41,055,000 | 46,738,000 | 59,281,000 | 63,663,000 |
operating lease liabilities, non-current | 41,921,000 | 44,285,000 | 46,597,000 | 48,851,000 | 50,994,000 | 51,441,000 | 53,323,000 | 55,159,000 | 56,894,000 | 58,576,000 | 60,221,000 | 61,826,000 | 63,168,000 | 64,636,000 | 66,074,000 | 67,475,000 | 66,650,000 | 65,684,000 | |
other non-current liabilities | 517,000 | 2,681,000 | 3,030,000 | 3,141,000 | 3,253,000 | 3,565,000 | 3,439,000 | 3,551,000 | 3,664,000 | 3,776,000 | 3,888,000 | 4,001,000 | 4,113,000 | 4,227,000 | 4,340,000 | 4,453,000 | 4,566,000 | 5,012,000 | 900,000 |
total liabilities | 91,850,000 | 78,844,000 | 86,530,000 | 93,277,000 | 108,035,000 | 88,518,000 | 87,641,000 | 91,063,000 | 95,077,000 | 97,416,000 | 98,499,000 | 96,624,000 | 104,309,000 | 157,243,000 | 153,632,000 | 190,854,000 | 197,619,000 | 211,860,000 | 207,912,000 |
commitments and contingencies | |||||||||||||||||||
stockholders’ equity: | |||||||||||||||||||
preferred stock, 0.0001 par value... | |||||||||||||||||||
common stock, 0.0001 par value... | 2,000 | 2,000 | 1,000 | 30,000 | 29,000 | 26,000 | 26,000 | 25,000 | 25,000 | 25,000 | 25,000 | 25,000 | 25,000 | 25,000 | 25,000 | 25,000 | 24,000 | 24,000 | 24,000 |
additional paid-in capital1 | 1,867,512,000 | 1,807,749,000 | 1,738,850,000 | ||||||||||||||||
accumulated other comprehensive income | 242,000 | 201,000 | 57,000 | 158,000 | 291,000 | 760,000 | -1,623,000 | -65,000 | 73,000 | ||||||||||
accumulated deficit | -1,619,554,000 | -1,478,831,000 | -1,439,985,000 | -1,397,301,000 | -1,345,106,000 | -1,153,171,000 | -1,108,588,000 | -1,062,779,000 | -1,002,112,000 | -949,182,000 | -898,329,000 | -834,439,000 | -767,480,000 | -759,083,000 | -688,829,000 | -652,506,000 | -584,362,000 | -500,656,000 | -451,781,000 |
total stockholders’ equity | 248,202,000 | 329,121,000 | 298,923,000 | 336,521,000 | 382,824,000 | 530,697,000 | 566,501,000 | 603,157,000 | 654,952,000 | 697,573,000 | 736,855,000 | 783,826,000 | 833,252,000 | 820,026,000 | 868,042,000 | 881,249,000 | 929,787,000 | ||
total liabilities and stockholders’ equity | 340,052,000 | 407,965,000 | 385,453,000 | 429,798,000 | 490,859,000 | 619,215,000 | 654,142,000 | 694,220,000 | 750,029,000 | 794,989,000 | 835,354,000 | 880,450,000 | 937,561,000 | 977,269,000 | 1,021,674,000 | 1,072,103,000 | |||
revenue | 15,000 | 8,000 | 7,000 | 34,000 | 13,000 | 3,000 | 25,000 | 27,000 | 65,000 | 3,000 | 35,741,000 | 553,000 | |||||||
operating expenses: | |||||||||||||||||||
research and development | 28,172,000 | 34,857,000 | 43,447,000 | 39,500,000 | 40,261,000 | 43,174,000 | 43,849,000 | 47,471,000 | 44,630,000 | 41,607,000 | 43,719,000 | 35,830,000 | |||||||
general and administrative | 10,687,000 | 9,786,000 | 14,046,000 | 11,769,000 | 12,256,000 | 13,494,000 | 15,507,000 | 19,030,000 | 19,279,000 | 26,084,000 | 30,454,000 | 34,421,000 | |||||||
other operating income | -1,591,000 | -119,000 | -730,000 | -976,000 | -1,090,000 | -292,000 | -569,000 | -1,288,000 | -1,251,000 | -1,171,000 | -1,122,000 | ||||||||
impairment of long-lived assets | 1,443,000 | ||||||||||||||||||
total operating expenses | 37,268,000 | 47,148,000 | 57,374,000 | 50,539,000 | 51,541,000 | 55,578,000 | 59,064,000 | 65,932,000 | 62,621,000 | 66,440,000 | 73,002,000 | 69,129,000 | |||||||
income from operations | -37,253,000 | -47,140,000 | -57,367,000 | -50,505,000 | -51,528,000 | -55,575,000 | -59,039,000 | -65,905,000 | -62,556,000 | -66,437,000 | -37,261,000 | -68,576,000 | |||||||
interest income | 3,266,000 | 3,276,000 | 3,862,000 | 5,965,000 | 6,364,000 | 6,819,000 | 6,608,000 | 5,264,000 | 4,497,000 | 2,251,000 | 952,000 | 397,000 | |||||||
other income | -4,859,000 | 1,180,000 | 1,310,000 | -43,000 | -645,000 | 1,090,000 | 1,578,000 | -326,000 | 1,100,000 | -1,068,000 | -14,000 | 35,000 | |||||||
impairment of other investments | -13,001,000 | -2,923,000 | -10,000,000 | -5,000,000 | |||||||||||||||
total other income | -1,593,000 | 4,456,000 | 5,172,000 | 5,922,000 | 5,719,000 | 8,186,000 | 2,015,000 | -4,403,000 | -3,817,000 | 938,000 | 432,000 | ||||||||
net income | -38,846,000 | -42,684,000 | -52,195,000 | -44,583,000 | -45,809,000 | -60,667,000 | -50,853,000 | -63,890,000 | -66,959,000 | -70,254,000 | -36,323,000 | -68,144,000 | |||||||
other comprehensive loss: | |||||||||||||||||||
net unrealized gain on marketable securities | 144,000 | -101,000 | 1,157,000 | 7,000 | -310,000 | 1,198,000 | 1,500,000 | 3,720,000 | |||||||||||
comprehensive loss | -38,702,000 | -42,785,000 | -52,328,000 | -43,426,000 | -45,802,000 | -60,977,000 | -49,655,000 | -62,390,000 | -63,239,000 | -71,899,000 | -38,074,000 | -73,121,000 | |||||||
net income per common share, basic and diluted1 | -2,130 | -2,890 | |||||||||||||||||
weighted-average shares used for eps calculation | 18,268,000 | 14,793,000 | 295,098,000 | 256,309,000 | 255,398,000 | 254,252,000 | 251,318,000 | 250,204,000 | 249,591,000 | 248,320,000 | 246,312,000 | 244,178,000 | |||||||
other operating income (income) | 1,062,000 | ||||||||||||||||||
additional paid-in capital | 1,733,634,000 | 1,727,610,000 | 1,683,082,000 | 1,675,460,000 | 1,666,315,000 | 1,657,133,000 | 1,647,911,000 | 1,637,538,000 | 1,622,119,000 | 1,608,306,000 | 1,589,080,000 | 1,565,197,000 | 1,540,330,000 | 1,515,748,000 | 1,487,171,000 | 1,473,639,000 | |||
net unrealized loss on marketable securities | -133,000 | -1,645,000 | -1,751,000 | -4,977,000 | |||||||||||||||
net income per common share, basic and diluted | -180 | -170 | -180 | -240 | -200 | -260 | -270 | -280 | -150 | -280 | |||||||||
success payment liabilities | 411,000 | 907,000 | 1,010,000 | 2,544,000 | 1,576,000 | 1,047,000 | 3,753,000 | 2,648,000 | 4,356,000 | 11,663,000 | 9,222,000 | 5,635,000 | 9,486,000 | 25,116,000 | 25,006,000 | ||||
accumulated other comprehensive loss | -397,000 | -404,000 | -94,000 | -1,181,000 | -2,379,000 | -3,879,000 | -7,599,000 | -9,996,000 | -8,351,000 | -6,600,000 | |||||||||
total other loss | -5,092,000 | ||||||||||||||||||
comprehensive loss: | |||||||||||||||||||
deferred revenue | 11,191,000 | 15,426,000 | 6,224,000 | 4,988,000 | 5,581,000 | 8,226,000 | |||||||||||||
deferred revenue, non-current | 37,163,000 | 32,927,000 | 77,871,000 | 79,665,000 | 81,883,000 | ||||||||||||||
liabilities, convertible preferred stock and stockholders’ equity | |||||||||||||||||||
convertible preferred stock, 0.0001 par value... | |||||||||||||||||||
stockholders’ equity | |||||||||||||||||||
total liabilities, convertible preferred stock and stockholders’ equity | 1,127,406,000 | ||||||||||||||||||
short-term marketable securities | 225,417,000 | 260,082,000 | |||||||||||||||||
long-term marketable securities | 317,511,000 | 150,261,000 | |||||||||||||||||
right-of-use assets | 47,236,000 | 48,424,000 | |||||||||||||||||
liabilities, convertible preferred stock and stockholders' equity | |||||||||||||||||||
stockholders' equity | |||||||||||||||||||
total stockholders' equity | 986,474,000 | 1,021,955,000 | |||||||||||||||||
total liabilities, convertible preferred stock and stockholders' equity | 1,198,334,000 | 1,229,867,000 | |||||||||||||||||
operating lease liabilities, net of current portion | 61,471,000 | ||||||||||||||||||
deferred revenue, net of current portion | 81,878,000 |
Cashflow Statements:
Quarterly
Annual
| Unit: USD | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cash flows from operating activities | ||||||||||||||||||
net loss | -140,723,000 | -38,846,000 | -42,684,000 | -52,195,000 | -191,935,000 | -44,583,000 | -45,809,000 | -60,667,000 | -52,930,000 | -50,853,000 | -63,890,000 | -66,959,000 | -8,397,000 | -70,254,000 | -36,323,000 | -68,144,000 | -83,706,000 | -48,875,000 |
adjustments to reconcile net loss to net cash from operating activities: | ||||||||||||||||||
acquired ipr&d expense | ||||||||||||||||||
stock-based compensation expense | 25,569,000 | 5,232,000 | 5,004,000 | 6,024,000 | 8,083,000 | 7,622,000 | 8,284,000 | 9,155,000 | 8,463,000 | 10,516,000 | 14,223,000 | 13,882,000 | 18,363,000 | 19,123,000 | 22,410,000 | 22,028,000 | 21,178,000 | 13,042,000 |
loss on securities purchase agreement put/call | 15,156,000 | |||||||||||||||||
depreciation and amortization expense | 2,397,000 | 2,566,000 | 3,135,000 | 3,441,000 | 5,026,000 | 4,680,000 | 4,901,000 | 5,024,000 | 5,057,000 | 5,104,000 | 5,062,000 | 5,027,000 | 5,041,000 | 4,621,000 | ||||
net amortization and accretion on marketable securities | -1,060,000 | -1,009,000 | -1,165,000 | -1,725,000 | -2,965,000 | -3,587,000 | -3,762,000 | -4,367,000 | -3,384,000 | -2,287,000 | -2,075,000 | -1,850,000 | -1,208,000 | -428,000 | ||||
non-cash lease income | -1,039,000 | -995,000 | -806,000 | -710,000 | -607,000 | -612,000 | -606,000 | -373,000 | -528,000 | -523,000 | -293,000 | |||||||
loss on property and equipment disposals | -166,000 | -249,000 | 2,468,000 | 1,291,000 | 924,000 | 402,000 | 0 | 15,000 | 437,000 | 642,000 | 6,000 | 13,000 | 714,000 | |||||
change in fair value of contingent consideration payable | 0 | 369,000 | -864,000 | -1,211,000 | ||||||||||||||
impairment of long-lived assets | 0 | 0 | ||||||||||||||||
change in fair value of success payment liabilities | 610,000 | 461,000 | -115,000 | -125,000 | -496,000 | -103,000 | -1,534,000 | 968,000 | 529,000 | -2,706,000 | 1,105,000 | -1,708,000 | -7,307,000 | 2,441,000 | 3,587,000 | -3,851,000 | -15,630,000 | 110,000 |
impairment of other investments | 0 | 0 | 0 | 13,001,000 | 0 | 0 | 2,923,000 | 10,000,000 | 0 | |||||||||
loss on marketable equity security | 1,000 | 1,000 | 2,000 | 26,000 | ||||||||||||||
changes in operating assets and liabilities: | ||||||||||||||||||
prepaid expenses, other current assets and other assets | -2,393,000 | 420,000 | 2,796,000 | 2,000,000 | 3,636,000 | -1,615,000 | -841,000 | 595,000 | 3,148,000 | -664,000 | 1,049,000 | -408,000 | -1,296,000 | -681,000 | 406,000 | -397,000 | ||
accounts payable | 325,000 | -779,000 | -231,000 | -1,654,000 | -2,036,000 | -568,000 | -517,000 | -113,000 | 425,000 | -1,410,000 | 380,000 | 2,069,000 | -526,000 | 23,000 | -1,767,000 | 2,937,000 | 99,000 | -988,000 |
accrued liabilities and other current liabilities | 4,904,000 | 572,000 | -3,330,000 | -9,788,000 | -1,254,000 | 3,094,000 | 516,000 | -3,606,000 | -1,739,000 | 4,612,000 | 2,268,000 | -5,860,000 | 5,373,000 | 1,323,000 | -766,000 | -6,393,000 | -6,250,000 | |
other non-current liabilities | -2,164,000 | -349,000 | -111,000 | -112,000 | -312,000 | 126,000 | -112,000 | -113,000 | -112,000 | -112,000 | -113,000 | -112,000 | -114,000 | -113,000 | -113,000 | -113,000 | -446,000 | |
net cash from operating activities | -32,251,000 | -28,577,000 | -34,458,000 | -54,738,000 | -47,242,000 | -35,042,000 | -38,094,000 | -42,016,000 | -40,635,000 | -37,686,000 | -39,161,000 | -46,212,000 | -40,267,000 | -37,103,000 | -44,333,000 | -47,852,000 | -33,173,000 | -25,532,000 |
capital expenditures | -304,000 | -62,000 | -314,000 | -91,000 | 77,000 | -86,000 | -501,000 | 190,000 | 2,000 | -226,000 | -1,295,000 | -1,138,000 | -6,820,000 | -2,781,000 | -3,724,000 | -9,626,000 | -11,095,000 | -12,746,000 |
free cash flows | -32,555,000 | -28,639,000 | -34,772,000 | -54,829,000 | -47,165,000 | -35,128,000 | -38,595,000 | -41,826,000 | -40,633,000 | -37,912,000 | -40,456,000 | -47,350,000 | -47,087,000 | -39,884,000 | -48,057,000 | -57,478,000 | -44,268,000 | -38,278,000 |
cash flows from investing activities | ||||||||||||||||||
purchases of property and equipment | -304,000 | -62,000 | -168,000 | -246,000 | -44,000 | -59,000 | -331,000 | -30,000 | -25,000 | -195,000 | -933,000 | -1,533,000 | -4,582,000 | -2,791,000 | -7,170,000 | -9,733,000 | -10,268,000 | -11,599,000 |
sales of property and equipment | 24,000 | 0 | ||||||||||||||||
purchases of marketable securities | -42,800,000 | -70,987,000 | -80,701,000 | -84,411,000 | -38,802,000 | -131,430,000 | -116,464,000 | -108,011,000 | -256,785,000 | -78,280,000 | -33,255,000 | -108,560,000 | -59,669,000 | -160,792,000 | -89,659,000 | -96,196,000 | -133,924,000 | -275,311,000 |
maturities of marketable securities | 52,910,000 | 74,135,000 | 93,516,000 | 154,123,000 | 123,697,000 | 133,407,000 | 161,802,000 | 130,035,000 | ||||||||||
acquisition of assets, net of cash acquired | ||||||||||||||||||
net cash from investing activities | -31,365,000 | 3,349,000 | 12,647,000 | 69,466,000 | 53,505,000 | 1,918,000 | 45,007,000 | 21,994,000 | -100,690,000 | 99,672,000 | 152,912,000 | 32,154,000 | 46,648,000 | -57,085,000 | 25,019,000 | -26,122,000 | -73,902,000 | -144,874,000 |
cash flows from financing activities | ||||||||||||||||||
proceeds from securities purchase agreement equity issuance | 0 | |||||||||||||||||
proceeds from exercise of stock options | -1,000 | 0 | 52,000 | 103,000 | 151,000 | 72,000 | 325,000 | 5,127,000 | 1,570,000 | 2,555,000 | 7,399,000 | 529,000 | ||||||
proceeds from employee stock purchase plan | 181,000 | 0 | 438,000 | 0 | 731,000 | 0 | 632,000 | 0 | ||||||||||
taxes paid related to net share settlement of equity awards | 1,000 | 0 | 0 | 0 | -76,000 | -123,000 | -215,000 | -50,000 | -69,000 | -94,000 | ||||||||
net cash from financing activities | 222,000 | 50,000,000 | 183,000 | 1,000 | 437,000 | 0 | 862,000 | 27,000 | 759,000 | -143,000 | 1,196,000 | -69,000 | 863,000 | 4,760,000 | 2,457,000 | 2,555,000 | 7,399,000 | -531,000 |
net increase in cash, cash equivalents and restricted cash | -63,394,000 | 14,729,000 | 6,700,000 | -33,124,000 | -140,566,000 | 61,843,000 | 7,244,000 | -89,428,000 | -16,857,000 | -71,419,000 | -99,676,000 | -170,937,000 | ||||||
cash, cash equivalents and restricted cash at beginning of period | 0 | 0 | 0 | 107,287,000 | 0 | 0 | 0 | 145,931,000 | 0 | 0 | 0 | 123,834,000 | 0 | 0 | 0 | 294,294,000 | 0 | 0 |
cash, cash equivalents and restricted cash at end of period | -63,394,000 | 24,772,000 | -21,628,000 | 122,016,000 | 6,700,000 | -33,124,000 | 7,775,000 | 125,936,000 | -140,566,000 | 61,843,000 | 114,947,000 | 109,707,000 | 7,244,000 | -89,428,000 | -16,857,000 | 222,875,000 | -99,676,000 | -170,937,000 |
represented by: | ||||||||||||||||||
cash and cash equivalents | -63,394,000 | 24,771,000 | -21,524,000 | 120,328,000 | 5,298,000 | -33,125,000 | 7,774,000 | 125,650,000 | -140,567,000 | 61,842,000 | 114,946,000 | 109,426,000 | 7,243,000 | -89,428,000 | -16,857,000 | 222,596,000 | -99,676,000 | -170,937,000 |
restricted cash | 0 | 1,000 | -104,000 | 1,688,000 | 1,402,000 | 1,000 | 1,000 | 286,000 | 1,000 | 1,000 | 1,000 | 281,000 | 1,000 | 0 | 0 | 279,000 | 0 | 0 |
total | -63,394,000 | 24,772,000 | -21,628,000 | 122,016,000 | 6,700,000 | -33,124,000 | 7,775,000 | 125,936,000 | -140,566,000 | 61,843,000 | 114,947,000 | 109,707,000 | 7,244,000 | -89,428,000 | -16,857,000 | 222,875,000 | -99,676,000 | -170,937,000 |
supplemental cash flow information | ||||||||||||||||||
cash paid for amounts included in the measurement of lease liabilities | 3,168,000 | 3,167,000 | 3,157,000 | 3,095,000 | 3,018,000 | 2,898,000 | 2,892,000 | 2,659,000 | 2,815,000 | 2,815,000 | 2,809,000 | 2,406,000 | 2,734,000 | 2,737,000 | 2,727,000 | 2,672,000 | 2,888,000 | 2,759,000 |
non-cash investing and financing activities: | ||||||||||||||||||
equity issued for acquisition | ||||||||||||||||||
securities purchase agreement put/call issuance | 0 | |||||||||||||||||
equity issued for contingent consideration - immpact bio usa inc. acquisition | ||||||||||||||||||
contingent consideration payable related to the purchase of the ipr&d asset on closing date | ||||||||||||||||||
purchases of property and equipment included in accounts payable and accrued liabilities | -146,000 | 155,000 | 121,000 | -27,000 | -170,000 | 220,000 | 27,000 | -31,000 | -362,000 | 395,000 | -2,238,000 | 10,000 | 3,446,000 | 107,000 | -827,000 | -1,147,000 | ||
equity issued for contingent consideration — immpact bio usa inc. acquisition | ||||||||||||||||||
net decrease in cash, cash equivalents and restricted cash | -19,995,000 | -14,127,000 | ||||||||||||||||
gain on marketable equity security | 17,000 | 102,000 | ||||||||||||||||
change in fair value of equity warrant | 0 | |||||||||||||||||
gain on other investments | ||||||||||||||||||
deferred revenue | -48,354,000 | 1,000 | -35,742,000 | -558,000 | -2,811,000 | -2,640,000 | ||||||||||||
operating lease liabilities, non-current | 1,524,000 | 1,196,000 | 0 | 2,135,000 | ||||||||||||||
cash received for amounts related to tenant improvement allowances | 1,523,000 | 1,196,000 | 0 | 2,042,000 | 2,232,000 | 5,663,000 | ||||||||||||
issuance of common stock related to the purchase of the ipr&d asset on closing date | ||||||||||||||||||
acquisition of pact series d convertible preferred shares | ||||||||||||||||||
remeasurement of operating lease right-of-use asset for lease modification | 2,000 | 18,000 | 6,000 | 5,000 | ||||||||||||||
gain on marketable equity securities | -1,535,000 | |||||||||||||||||
non-cash lease expense | -449,000 | -441,000 | -214,000 | -405,000 | ||||||||||||||
gain on net operating lease liability disposal | ||||||||||||||||||
sales and maturities of marketable securities | 156,120,000 | 178,147,000 | 187,100,000 | 142,247,000 | 110,899,000 | 106,498,000 | 121,848,000 | 79,807,000 | 70,330,000 | 142,036,000 | ||||||||
proceeds from initial public offering, net of issuance costs | 0 | -1,060,000 | ||||||||||||||||
conversion of convertible preferred stock to common stock upon closing of initial public offering | 0 | 0 | ||||||||||||||||
lease expense, net of gain on lease remeasurement | ||||||||||||||||||
expense in connection with asset acquisition | ||||||||||||||||||
purchases of other investments | ||||||||||||||||||
proceeds from issuance of convertible preferred stock, net of issuance costs | ||||||||||||||||||
payments for the repurchase of common stock | ||||||||||||||||||
payments for the repurchase of convertible preferred stock | ||||||||||||||||||
operating lease right-of-use assets obtained in exchange for lease obligations | ||||||||||||||||||
other investments received for sale of assets | ||||||||||||||||||
change in fair value of warrants | 14,000 | -28,000 | 57,000 | 42,000 | ||||||||||||||
deferred offering costs included in accounts payable and accrued liabilities | ||||||||||||||||||
depreciation and amortization | 4,187,000 | 4,565,000 | 4,091,000 | |||||||||||||||
net amortization or accretion on marketable securities | 475,000 | 467,000 | 552,000 | |||||||||||||||
loss on property equipment and disposals | 84,000 | |||||||||||||||||
non-cash expense in connection with asset acquisition | ||||||||||||||||||
loss on remeasurement of convertible preferred stock tranche liabilities | ||||||||||||||||||
expense in connection with equity issuances | ||||||||||||||||||
prepaid expenses and other assets | -176,000 | |||||||||||||||||
non-cash deemed dividends on convertible preferred stock | ||||||||||||||||||
payments for the repurchase of preferred stock | ||||||||||||||||||
remeasurement of operating lease right of use asset for lease modification | -228,000 | |||||||||||||||||
other | ||||||||||||||||||
prepaid expense and other assets | ||||||||||||||||||
accrued liabilities and other liabilities |