Janux Therapeutics(NASDAQ:JANX)

Janux Therapeutics is an innovative clinical-stage biopharmaceutical company developing next-generation therapeutics based on applying its proprietary technology to its Tumor Activated T Cell Engager (TRACTr) and Tumor Activated Immunomodulator (TRACIr) platforms to better treat patients suffering f...
Website: https://www.januxrx.com/
Founded: 2017
IPO Price: $17 (Jun 11, 2021)
CEO: David Campbell
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At a glance:
Bull Thesis:
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Income Statements:
Quarterly
Annual
| Unit: USD | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
collaboration revenue | 3,733,000 | 10,000,000 | 439,000 | 8,897,000 | 1,252,000 | 2,461,000 | 2,517,000 | 1,057,000 | 2,048,000 | 2,845,000 | 1,813,000 | 2,365,000 | 1,589,000 | 1,616,000 | 1,159,000 | 482,000 | ||||
operating expenses: | ||||||||||||||||||||
research and development | 26,813,000 | 31,548,000 | 34,629,000 | 34,664,000 | 25,055,000 | 20,806,000 | 18,614,000 | 14,898,000 | 14,070,000 | 12,241,000 | 11,892,000 | 14,924,000 | 15,865,000 | 15,434,000 | 13,737,000 | 14,086,000 | 10,184,000 | 11,169,000 | 8,406,000 | 4,737,000 |
general and administrative | 11,133,000 | 10,853,000 | 10,622,000 | 10,454,000 | 9,842,000 | 8,216,000 | 17,667,000 | 7,821,000 | 7,343,000 | 6,357,000 | 6,438,000 | 6,881,000 | 6,464,000 | 5,677,000 | 6,098,000 | 5,540,000 | 4,947,000 | 3,937,000 | 3,656,000 | 1,997,000 |
total operating expenses | 37,946,000 | 42,401,000 | 45,251,000 | 45,118,000 | 34,897,000 | 29,022,000 | 36,281,000 | 22,719,000 | 21,413,000 | 18,598,000 | 18,330,000 | 21,805,000 | 22,329,000 | 21,111,000 | 19,835,000 | 19,626,000 | 15,131,000 | 15,106,000 | 12,062,000 | 6,734,000 |
income from operations | -34,213,000 | -42,401,000 | -35,251,000 | -45,118,000 | -34,897,000 | -29,022,000 | -35,842,000 | -13,822,000 | -20,161,000 | -16,137,000 | -15,813,000 | -20,748,000 | -20,281,000 | -18,266,000 | -18,022,000 | -17,261,000 | -13,542,000 | -13,490,000 | -10,903,000 | -6,252,000 |
yoy | -1.96% | 46.10% | -1.65% | 226.42% | 73.09% | 79.85% | 126.66% | -33.38% | -0.59% | -11.66% | -12.26% | 20.20% | 49.76% | 35.40% | 65.29% | 176.09% | ||||
qoq | -19.31% | 20.28% | -21.87% | 29.29% | 20.24% | -19.03% | 159.31% | -31.44% | 24.94% | 2.05% | -23.79% | 2.30% | 11.03% | 1.35% | 4.41% | 27.46% | 0.39% | 23.73% | 74.39% | |
other income: | ||||||||||||||||||||
interest income | 9,852,000 | 10,455,000 | 10,938,000 | 11,260,000 | 11,389,000 | 8,806,000 | 7,783,000 | 7,863,000 | 5,401,000 | 4,379,000 | 4,245,000 | 3,240,000 | 2,822,000 | 2,201,000 | 1,326,000 | 373,000 | 132,000 | 74,000 | 137,000 | 46,000 |
total other income | 9,852,000 | 10,455,000 | 10,938,000 | 11,260,000 | 11,389,000 | 8,806,000 | 7,783,000 | 7,863,000 | 5,401,000 | 4,379,000 | 4,245,000 | 3,240,000 | 2,822,000 | 2,201,000 | 1,326,000 | 373,000 | 132,000 | 74,000 | 137,000 | 46,000 |
net income | -24,361,000 | -31,946,000 | -24,313,000 | -33,858,000 | -23,508,000 | -20,216,000 | -28,059,000 | -5,959,000 | -14,760,000 | -11,758,000 | -11,568,000 | -17,508,000 | -17,459,000 | -16,065,000 | -16,696,000 | -16,888,000 | -13,410,000 | -13,416,000 | -10,766,000 | -6,206,000 |
yoy | 3.63% | 58.02% | -13.35% | 468.18% | 59.27% | 71.93% | 142.56% | -65.96% | -15.46% | -26.81% | -30.71% | 3.67% | 30.19% | 19.75% | 55.08% | 172.12% | ||||
qoq | -23.74% | 31.39% | -28.19% | 44.03% | 16.28% | -27.95% | 370.87% | -59.63% | 25.53% | 1.64% | -33.93% | 0.28% | 8.68% | -3.78% | -1.14% | 25.94% | -0.04% | 24.61% | 73.48% | |
other comprehensive gain: | ||||||||||||||||||||
unrealized gain on available-for-sale securities | -3,740,000 | -246,000 | 815,000 | -9,000 | 1,593,000 | -5,668,000 | 9,447,000 | -1,092,000 | -1,189,000 | 1,840,000 | -115,000 | -321,000 | 796,000 | -501,750 | -370,000 | -340,000 | -294,000 | 7,000 | -17,000 | |
comprehensive loss | -28,101,000 | -32,192,000 | -23,498,000 | -33,867,000 | -21,915,000 | -25,884,000 | -18,612,000 | -7,051,000 | -15,949,000 | -9,918,000 | -11,683,000 | -17,829,000 | -16,663,000 | -15,323,000 | -17,066,000 | -17,228,000 | -14,977,000 | -13,710,000 | -10,759,000 | -6,223,000 |
net loss per common share, basic and diluted | -390 | -510 | -390 | -550 | -380 | -350 | -510 | -110 | -300 | -240 | -250 | -420 | -420 | -390 | -400 | -410 | -320 | -290 | -260 | -620 |
weighted-average shares of common stock outstanding, basic and diluted | 62,665,717,000 | 61,966,999,000 | 62,023,685,000 | 61,902,411,000 | 61,791,721,000 | 53,751,480,000 | 54,628,670,000 | 54,451,666,000 | 49,049,741,000 | 44,016,283,000 | 45,708,649,000 | 41,836,238,000 | 41,763,971,000 | 41,469,631,000 | 41,526,524,000 | 41,448,743,000 | 41,315,482,000 | 23,530,252,000 | 41,134,102,000 | 10,033,328,000 |
other comprehensive loss: | ||||||||||||||||||||
unrealized loss on available-for-sale securities | -1,567,000 | |||||||||||||||||||
interest expense – related parties | ||||||||||||||||||||
change in fair value of convertible promissory notes – related parties | ||||||||||||||||||||
increase in fair value of convertible promissory notes – related parties |
Balance Sheets:
Quarterly
Annual
| Unit: USD | 2026-03-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
assets | |||||||||||||||||||
current assets: | |||||||||||||||||||
cash and cash equivalents | 51,828,000 | 48,389,000 | 52,446,000 | 73,743,000 | 430,605,000 | 26,754,000 | 14,662,000 | 212,803,000 | 19,205,000 | 17,152,000 | 33,703,000 | 30,355,000 | 51,426,000 | 64,752,000 | 58,403,000 | 55,129,000 | 35,582,000 | 39,389,000 | 251,625,000 |
accounts receivable | 35,000,000 | 7,500,000 | 519,000 | 750,000 | 500,000 | 375,000 | |||||||||||||
short-term investments | 904,558,000 | 940,604,000 | 943,565,000 | 940,403,000 | 594,568,000 | 631,277,000 | 631,631,000 | 438,960,000 | 324,823,000 | 332,560,000 | 269,586,000 | 286,520,000 | 275,590,000 | 274,008,000 | 295,893,000 | 306,071,000 | 339,383,000 | 348,118,000 | 142,570,000 |
prepaid expenses and other current assets | 10,663,000 | 9,093,000 | 9,542,000 | 9,193,000 | 8,493,000 | 8,290,000 | 8,146,000 | 6,384,000 | 5,213,000 | 5,483,000 | 6,013,000 | 3,774,000 | 5,423,000 | 5,070,000 | 3,769,000 | 3,454,000 | 2,054,000 | 2,081,000 | 2,038,000 |
total current assets | 1,002,049,000 | 998,086,000 | 1,005,553,000 | 1,023,339,000 | 1,033,666,000 | 666,321,000 | 661,939,000 | 658,666,000 | 349,241,000 | 355,195,000 | 309,302,000 | 321,399,000 | 332,439,000 | 344,330,000 | 358,065,000 | 364,654,000 | 377,019,000 | 389,588,000 | 396,608,000 |
restricted cash | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | ||
property and equipment | 3,546,000 | 4,314,000 | 4,688,000 | 4,947,000 | 4,864,000 | 5,373,000 | 5,940,000 | 6,517,000 | 7,003,000 | 7,317,000 | 7,378,000 | 7,203,000 | 7,086,000 | 6,514,000 | 3,517,000 | 2,660,000 | 1,412,000 | 1,118,000 | 215,000 |
operating lease right-of-use assets | 17,870,000 | 18,923,000 | 18,462,000 | 18,878,000 | 19,286,000 | 19,686,000 | 20,077,000 | 20,461,000 | 20,838,000 | 21,208,000 | 21,571,000 | 21,927,000 | 22,279,000 | 22,663,000 | 22,760,000 | 130,000 | 185,000 | 238,000 | |
other long-term assets | 3,944,000 | 2,627,000 | 2,693,000 | 2,792,000 | 2,884,000 | 2,823,000 | 2,640,000 | 2,524,000 | 2,509,000 | 2,314,000 | 2,433,000 | 1,611,000 | 1,390,000 | 1,433,000 | 207,000 | 337,000 | 392,000 | 140,000 | |
total assets | 1,028,225,000 | 1,024,766,000 | 1,032,212,000 | 1,050,772,000 | 1,061,516,000 | 695,019,000 | 691,412,000 | 688,984,000 | 380,407,000 | 386,850,000 | 341,500,000 | 352,956,000 | 364,010,000 | 375,756,000 | 385,365,000 | 368,597,000 | 379,824,000 | 391,084,000 | 396,823,000 |
liabilities and stockholders’ equity | |||||||||||||||||||
current liabilities: | |||||||||||||||||||
accounts payable | 3,376,000 | 3,395,000 | 3,477,000 | 2,351,000 | 4,026,000 | 2,462,000 | 1,253,000 | 2,254,000 | 2,424,000 | 2,505,000 | 1,910,000 | 2,051,000 | 2,159,000 | 2,866,000 | 3,000,000 | 1,939,000 | 2,458,000 | 3,613,000 | 354,000 |
accrued expenses | 15,476,000 | 22,156,000 | 16,029,000 | 13,340,000 | 11,684,000 | 13,022,000 | 8,568,000 | 5,810,000 | 7,387,000 | ||||||||||
current portion of deferred revenue | 37,591,000 | 94,000 | 972,000 | 1,705,000 | 3,648,000 | 5,340,000 | 4,935,000 | 5,406,000 | 5,906,000 | 5,371,000 | 4,649,000 | 5,163,000 | 5,264,000 | 5,065,000 | |||||
current portion of operating lease liabilities | 2,472,000 | 2,280,000 | 1,873,000 | 1,811,000 | 1,749,000 | 1,689,000 | 1,630,000 | 1,573,000 | 1,517,000 | 1,462,000 | 1,408,000 | 1,356,000 | 763,000 | 88,000 | 153,000 | 194,000 | 212,000 | ||
total current liabilities | 58,915,000 | 27,831,000 | 21,379,000 | 17,502,000 | 17,459,000 | 17,173,000 | 11,545,000 | 10,609,000 | 13,033,000 | 14,471,000 | 17,904,000 | 16,114,000 | 16,507,000 | 16,335,000 | 12,994,000 | 12,515,000 | 12,797,000 | 12,471,000 | 9,205,000 |
deferred revenue, net of current portion | 8,676,000 | 307,000 | 1,394,000 | 2,221,000 | 3,816,000 | 5,289,000 | 700,000 | 1,840,000 | 2,823,000 | ||||||||||
operating lease liabilities, net of current portion | 19,099,000 | 20,380,000 | 20,317,000 | 20,801,000 | 21,276,000 | 21,742,000 | 22,190,000 | 22,612,000 | 23,025,000 | 23,431,000 | 23,820,000 | 24,184,000 | 24,542,000 | 24,092,000 | 23,268,000 | 23,000 | |||
total liabilities | 86,690,000 | 48,211,000 | 41,696,000 | 38,303,000 | 38,735,000 | 38,915,000 | 33,735,000 | 33,221,000 | 36,058,000 | 37,902,000 | 42,031,000 | 41,692,000 | 43,270,000 | 44,243,000 | 41,551,000 | 12,515,000 | 13,497,000 | 14,334,000 | 12,028,000 |
commitments and contingencies | |||||||||||||||||||
stockholders’ equity: | |||||||||||||||||||
preferred stock, 0.001 par value... | |||||||||||||||||||
common stock, 0.001 par value... | 60,000 | 60,000 | 59,000 | 59,000 | 59,000 | 52,000 | 52,000 | 51,000 | 46,000 | 46,000 | 42,000 | 42,000 | 42,000 | 42,000 | 42,000 | 41,000 | 41,000 | 41,000 | 41,000 |
additional paid-in capital | 1,316,642,000 | 1,291,369,000 | 1,281,833,000 | 1,269,919,000 | 1,258,316,000 | 865,762,000 | 848,723,000 | 839,759,000 | 512,401,000 | 507,082,000 | 445,924,000 | 439,890,000 | 432,703,000 | 428,153,000 | 423,388,000 | 418,429,000 | 413,967,000 | 410,680,000 | 407,966,000 |
accumulated other comprehensive income | 576,000 | 4,562,000 | 3,747,000 | 3,756,000 | 2,163,000 | 7,831,000 | -1,616,000 | -524,000 | 665,000 | -270,000 | 24,000 | 17,000 | |||||||
accumulated deficit | -375,743,000 | -319,436,000 | -295,123,000 | -261,265,000 | -237,757,000 | -217,541,000 | -189,482,000 | -183,523,000 | -168,763,000 | -157,005,000 | -145,437,000 | -127,929,000 | -110,470,000 | -94,405,000 | -77,709,000 | -60,821,000 | -47,411,000 | -33,995,000 | -23,229,000 |
total stockholders’ equity | 941,535,000 | 976,555,000 | 990,516,000 | 1,012,469,000 | 1,022,781,000 | 656,104,000 | 657,677,000 | 655,763,000 | 344,349,000 | 348,948,000 | 299,469,000 | 311,264,000 | 320,740,000 | 331,513,000 | 343,814,000 | 356,082,000 | 366,327,000 | 376,750,000 | 384,795,000 |
total liabilities and stockholders’ equity | 1,028,225,000 | 1,024,766,000 | 1,032,212,000 | 1,050,772,000 | 1,061,516,000 | 695,019,000 | 691,412,000 | 688,984,000 | 380,407,000 | 386,850,000 | 341,500,000 | 352,956,000 | 364,010,000 | 375,756,000 | 385,365,000 | 368,597,000 | |||
accrued liabilities | 6,831,000 | 9,216,000 | 7,737,000 | 8,010,000 | 7,240,000 | 4,043,000 | 5,074,000 | 3,779,000 | 2,030,000 | 2,286,000 | |||||||||
unvested stock liabilities | 25,000 | 30,000 | 35,000 | 169,000 | 323,000 | 492,000 | 700,000 | 1,203,000 | 1,352,000 | ||||||||||
accumulated other comprehensive loss | -1,175,000 | -1,060,000 | -739,000 | -1,535,000 | -2,277,000 | -1,907,000 | -1,567,000 | ||||||||||||
liabilities, convertible preferred stock and stockholders’ equity | |||||||||||||||||||
convertible preferred stock, 0.001 par value... | |||||||||||||||||||
stockholders’ equity | |||||||||||||||||||
total liabilities, convertible preferred stock and stockholders’ equity | 379,824,000 | 391,084,000 | 396,823,000 | ||||||||||||||||
unvested stock liability | 1,500,000 |
Cashflow Statements:
Quarterly
Annual
| Unit: USD | 2026-03-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cash flows from operating activities | ||||||||||||||||||
net loss | -24,361,000 | -24,313,000 | -33,858,000 | -23,508,000 | -20,216,000 | -28,059,000 | -5,959,000 | -14,760,000 | -11,758,000 | -11,568,000 | -17,508,000 | -17,459,000 | -16,065,000 | -16,696,000 | -16,888,000 | -13,410,000 | -13,416,000 | -10,766,000 |
adjustments to reconcile net loss to net cash from operating activities: | ||||||||||||||||||
depreciation | 469,000 | 501,000 | 541,000 | 519,000 | 512,000 | 510,000 | 506,000 | 532,000 | 531,000 | 500,000 | 471,000 | 453,000 | 403,000 | 249,000 | 108,000 | 81,000 | 64,000 | 27,000 |
stock-based compensation | 9,269,000 | 9,044,000 | 10,960,000 | 10,702,000 | 6,251,000 | 15,387,000 | 5,757,000 | 5,625,000 | 4,483,000 | 4,548,000 | 5,501,000 | 5,473,000 | 4,205,000 | 4,596,000 | 4,444,000 | 3,958,000 | 2,944,000 | 2,566,000 |
accretion of discounts on investments | -2,624,000 | -4,623,000 | -5,206,000 | -4,221,000 | -2,927,000 | -2,898,000 | -2,973,000 | -1,787,000 | -2,061,000 | -2,108,000 | -1,841,000 | -1,678,000 | ||||||
changes in operating assets and liabilities: | ||||||||||||||||||
accounts receivable | -35,000,000 | -6,981,000 | -519,000 | -750,000 | 0 | 375,000 | ||||||||||||
prepaid expenses and other current assets | -1,343,000 | 449,000 | -349,000 | -700,000 | -203,000 | -144,000 | -1,762,000 | -1,171,000 | 270,000 | 530,000 | -2,239,000 | 1,649,000 | -81,000 | -1,301,000 | -587,000 | -1,400,000 | 27,000 | -43,000 |
other long-term assets | -1,336,000 | 66,000 | 99,000 | 92,000 | -61,000 | -183,000 | -116,000 | -15,000 | -195,000 | 119,000 | -822,000 | -221,000 | -313,000 | -1,142,000 | 130,000 | 55,000 | -252,000 | |
accounts payable | -1,612,000 | -168,000 | 1,113,000 | -1,637,000 | 1,559,000 | 1,175,000 | -694,000 | -456,000 | 327,000 | 228,000 | -171,000 | -107,000 | 223,000 | -634,000 | 857,000 | -740,000 | -482,000 | 2,584,000 |
accrued expenses | -2,030,000 | 6,179,000 | 2,893,000 | 1,734,000 | -1,634,000 | 4,573,000 | 3,060,000 | -1,573,000 | 426,000 | -1,987,000 | 1,443,000 | -560,000 | 1,005,000 | 2,887,000 | -894,000 | 1,158,000 | 1,921,000 | 409,000 |
deferred revenue | 46,267,000 | 0 | -94,000 | -878,000 | -733,000 | -1,943,000 | -1,999,000 | -682,000 | -1,298,000 | -2,095,000 | -938,000 | 6,011,000 | -1,214,000 | -1,241,000 | -784,000 | |||
operating lease right-of-use assets and liabilities | -36,000 | 9,000 | -6,000 | -5,000 | -6,000 | 2,000 | 19,000 | 20,000 | 19,000 | 28,000 | 44,000 | 587,000 | 1,597,000 | 833,000 | 845,000 | 14,000 | 12,000 | |
net cash from operating activities | -12,337,000 | -12,856,000 | -23,813,000 | -17,024,000 | -16,725,000 | -2,231,000 | -10,021,000 | -14,837,000 | -9,901,000 | -11,709,000 | -15,054,000 | -13,911,000 | -11,913,000 | -13,414,000 | -6,073,000 | -11,522,000 | -10,481,000 | -5,854,000 |
capital expenditures | -273,000 | -93,000 | -473,000 | -371,000 | -42,000 | -25,000 | -95,000 | -197,000 | -515,000 | -470,000 | -580,000 | -285,000 | -2,056,000 | -2,520,000 | -898,000 | -971,000 | -1,173,000 | -77,000 |
free cash flows | -12,610,000 | -12,949,000 | -24,286,000 | -17,395,000 | -16,767,000 | -2,256,000 | -10,116,000 | -15,034,000 | -10,416,000 | -12,179,000 | -15,634,000 | -14,196,000 | -13,969,000 | -15,934,000 | -6,971,000 | -12,493,000 | -11,654,000 | -5,931,000 |
cash flows from investing activities | ||||||||||||||||||
purchases of property and equipment | -273,000 | -93,000 | -473,000 | -371,000 | -42,000 | -25,000 | -95,000 | -197,000 | -515,000 | -470,000 | -580,000 | -285,000 | -2,056,000 | -2,520,000 | -898,000 | -971,000 | -1,173,000 | -77,000 |
purchases of short-term investments | -112,751,000 | -117,969,000 | -92,685,000 | -371,291,000 | -24,032,000 | -32,466,000 | -235,540,000 | -178,539,000 | -33,112,000 | -135,981,000 | -76,546,000 | -71,705,000 | -86,048,000 | -94,467,000 | -68,813,000 | -45,061,000 | -103,501,000 | -227,607,000 |
maturities of short-term investments | 121,310,000 | 126,368,000 | 94,720,000 | 31,270,000 | 58,000,000 | 45,165,000 | 44,750,000 | 65,000,000 | 44,750,000 | 75,000,000 | 95,000,000 | 63,250,000 | 86,500,000 | 116,750,000 | 78,750,000 | 77,100,000 | 112,000,000 | |
net cash from investing activities | 8,286,000 | 8,306,000 | 1,562,000 | -340,392,000 | 33,926,000 | 12,674,000 | -190,885,000 | -113,736,000 | 11,123,000 | -61,451,000 | 17,874,000 | -8,740,000 | -1,604,000 | 19,763,000 | 9,039,000 | 31,068,000 | 7,326,000 | -205,539,000 |
cash flows from financing activities | ||||||||||||||||||
proceeds from exercise of common stock options | 3,545,000 | 901,000 | 1,657,000 | |||||||||||||||
payments of issuance costs | ||||||||||||||||||
net cash from financing activities | 3,545,000 | 493,000 | 954,000 | 554,000 | 386,650,000 | 1,649,000 | 2,765,000 | 322,171,000 | 831,000 | 56,609,000 | 528,000 | 1,580,000 | 191,000 | 0 | 308,000 | 1,000 | 164,000 | -843,000 |
net decrease in cash, cash equivalents and restricted cash | -506,000 | |||||||||||||||||
cash, cash equivalents and restricted cash – beginning of year | 53,150,000 | 0 | 0 | 431,421,000 | 0 | 0 | 0 | 20,021,000 | 0 | 0 | 0 | 52,242,000 | 0 | 0 | 0 | 36,398,000 | ||
cash, cash equivalents and restricted cash – end of period | 52,644,000 | -4,057,000 | -21,297,000 | 74,559,000 | 403,851,000 | 12,092,000 | -198,141,000 | 213,619,000 | 2,053,000 | -16,551,000 | 3,348,000 | 31,171,000 | ||||||
supplemental disclosure of noncash investing and financing activities | ||||||||||||||||||
unpaid property and equipment | 25,000 | 54,000 | -190,000 | 237,000 | -36,000 | -298,000 | -30,000 | 65,000 | 395,000 | -1,080,000 | 726,000 | |||||||
unrealized gain on available-for-sale securities | -3,740,000 | 815,000 | -9,000 | 1,593,000 | -5,668,000 | 9,447,000 | -1,092,000 | -1,189,000 | 1,840,000 | -115,000 | -321,000 | 796,000 | -370,000 | |||||
proceeds from exercise of common stock options and employee stock purchase plan | 493,000 | 8,442,000 | 1,649,000 | 831,000 | ||||||||||||||
proceeds from the issuance of common stock and pre-funded common stock warrants, net of issuance costs | 0 | 0 | -347,000 | 378,208,000 | 0 | -455,000 | 320,514,000 | 0 | ||||||||||
net increase in cash, cash equivalents and restricted cash | -356,862,000 | 403,851,000 | 193,598,000 | 2,053,000 | -16,551,000 | 3,348,000 | -21,071,000 | -13,326,000 | 6,349,000 | 3,274,000 | 19,547,000 | |||||||
operating lease liabilities arising from right-of-use assets | 344,000 | 0 | 0 | |||||||||||||||
unpaid issuance costs | ||||||||||||||||||
vesting of restricted common stock | 7,000 | 3,000 | 5,000 | 5,000 | 5,000 | 5,000 | 5,000 | 134,000 | 154,000 | 169,000 | 208,000 | 503,000 | 149,000 | 148,000 | ||||
unpaid equity issuance costs | 438,000 | -843,000 | ||||||||||||||||
proceeds from exercise of vested and unvested common stock options and employee stock purchase plan | 528,000 | 1,580,000 | 191,000 | 0 | 308,000 | 1,000 | ||||||||||||
loss on disposal of assets | 0 | 0 | ||||||||||||||||
amortization of premiums/discounts on investments | -1,292,000 | -768,000 | -99,000 | -24,000 | -58,000 | -79,000 | ||||||||||||
proceeds from issuance of series a convertible preferred stock, net of issuance costs | 0 | 0 | ||||||||||||||||
proceeds from issuance of series b convertible preferred stock, net of issuance costs | 0 | 0 | ||||||||||||||||
proceeds from initial public offering, net of issuance costs | 0 | -843,000 | ||||||||||||||||
cash, cash equivalents and restricted cash – end of year | 3,274,000 | 55,945,000 | ||||||||||||||||
conversion of convertible preferred stock in connection with initial public offering | 0 | 0 | ||||||||||||||||
unrealized loss on available-for-sale securities | ||||||||||||||||||
payment of initial public offering costs | ||||||||||||||||||
unpaid fixed asset additions | 396,000 | -815,000 | ||||||||||||||||
unrealized loss on short-term investments | -1,297,000 | |||||||||||||||||
noncash interest – related parties | ||||||||||||||||||
increase in fair value of convertible promissory notes – related parties | ||||||||||||||||||
proceeds from issuance of convertible promissory notes | ||||||||||||||||||
proceeds from issuance of series seed 2 convertible preferred stock, net of issuance costs | ||||||||||||||||||
conversion of convertible promissory notes and accrued interest into shares of convertible preferred stock | ||||||||||||||||||
unrealized gain on short-term investments | -294,000 | 7,000 | ||||||||||||||||
proceeds from exercise of vested and unvested common stock options | 0 | |||||||||||||||||
net increase in cash and cash equivalents | -212,236,000 | |||||||||||||||||
cash and cash equivalents – beginning of period | 0 | |||||||||||||||||
cash and cash equivalents – end of period | -212,236,000 |
