Quarterly
Annual
| Unit: USD | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
assets | ||||||||||||||||||
current assets: | ||||||||||||||||||
cash and cash equivalents | 48,389,000 | 52,446,000 | 73,743,000 | 430,605,000 | 26,754,000 | 14,662,000 | 212,803,000 | 19,205,000 | 17,152,000 | 33,703,000 | 30,355,000 | 51,426,000 | 64,752,000 | 58,403,000 | 55,129,000 | 35,582,000 | 39,389,000 | 251,625,000 |
short-term investments | 940,604,000 | 943,565,000 | 940,403,000 | 594,568,000 | 631,277,000 | 631,631,000 | 438,960,000 | 324,823,000 | 332,560,000 | 269,586,000 | 286,520,000 | 275,590,000 | 274,008,000 | 295,893,000 | 306,071,000 | 339,383,000 | 348,118,000 | 142,570,000 |
prepaid expenses and other current assets | 9,093,000 | 9,542,000 | 9,193,000 | 8,493,000 | 8,290,000 | 8,146,000 | 6,384,000 | 5,213,000 | 5,483,000 | 6,013,000 | 3,774,000 | 5,423,000 | 5,070,000 | 3,769,000 | 3,454,000 | 2,054,000 | 2,081,000 | 2,038,000 |
total current assets | 998,086,000 | 1,005,553,000 | 1,023,339,000 | 1,033,666,000 | 666,321,000 | 661,939,000 | 658,666,000 | 349,241,000 | 355,195,000 | 309,302,000 | 321,399,000 | 332,439,000 | 344,330,000 | 358,065,000 | 364,654,000 | 377,019,000 | 389,588,000 | 396,608,000 |
restricted cash | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | 816,000 | ||
property and equipment | 4,314,000 | 4,688,000 | 4,947,000 | 4,864,000 | 5,373,000 | 5,940,000 | 6,517,000 | 7,003,000 | 7,317,000 | 7,378,000 | 7,203,000 | 7,086,000 | 6,514,000 | 3,517,000 | 2,660,000 | 1,412,000 | 1,118,000 | 215,000 |
operating lease right-of-use assets | 18,923,000 | 18,462,000 | 18,878,000 | 19,286,000 | 19,686,000 | 20,077,000 | 20,461,000 | 20,838,000 | 21,208,000 | 21,571,000 | 21,927,000 | 22,279,000 | 22,663,000 | 22,760,000 | 130,000 | 185,000 | 238,000 | |
other long-term assets | 2,627,000 | 2,693,000 | 2,792,000 | 2,884,000 | 2,823,000 | 2,640,000 | 2,524,000 | 2,509,000 | 2,314,000 | 2,433,000 | 1,611,000 | 1,390,000 | 1,433,000 | 207,000 | 337,000 | 392,000 | 140,000 | |
total assets | 1,024,766,000 | 1,032,212,000 | 1,050,772,000 | 1,061,516,000 | 695,019,000 | 691,412,000 | 688,984,000 | 380,407,000 | 386,850,000 | 341,500,000 | 352,956,000 | 364,010,000 | 375,756,000 | 385,365,000 | 368,597,000 | 379,824,000 | 391,084,000 | 396,823,000 |
liabilities and stockholders’ equity | ||||||||||||||||||
current liabilities: | ||||||||||||||||||
accounts payable | 3,395,000 | 3,477,000 | 2,351,000 | 4,026,000 | 2,462,000 | 1,253,000 | 2,254,000 | 2,424,000 | 2,505,000 | 1,910,000 | 2,051,000 | 2,159,000 | 2,866,000 | 3,000,000 | 1,939,000 | 2,458,000 | 3,613,000 | 354,000 |
accrued expenses | 22,156,000 | 16,029,000 | 13,340,000 | 11,684,000 | 13,022,000 | 8,568,000 | 5,810,000 | 7,387,000 | ||||||||||
current portion of operating lease liabilities | 2,280,000 | 1,873,000 | 1,811,000 | 1,749,000 | 1,689,000 | 1,630,000 | 1,573,000 | 1,517,000 | 1,462,000 | 1,408,000 | 1,356,000 | 763,000 | 88,000 | 153,000 | 194,000 | 212,000 | ||
total current liabilities | 27,831,000 | 21,379,000 | 17,502,000 | 17,459,000 | 17,173,000 | 11,545,000 | 10,609,000 | 13,033,000 | 14,471,000 | 17,904,000 | 16,114,000 | 16,507,000 | 16,335,000 | 12,994,000 | 12,515,000 | 12,797,000 | 12,471,000 | 9,205,000 |
operating lease liabilities, net of current portion | 20,380,000 | 20,317,000 | 20,801,000 | 21,276,000 | 21,742,000 | 22,190,000 | 22,612,000 | 23,025,000 | 23,431,000 | 23,820,000 | 24,184,000 | 24,542,000 | 24,092,000 | 23,268,000 | 23,000 | |||
total liabilities | 48,211,000 | 41,696,000 | 38,303,000 | 38,735,000 | 38,915,000 | 33,735,000 | 33,221,000 | 36,058,000 | 37,902,000 | 42,031,000 | 41,692,000 | 43,270,000 | 44,243,000 | 41,551,000 | 12,515,000 | 13,497,000 | 14,334,000 | 12,028,000 |
commitments and contingencies | ||||||||||||||||||
stockholders’ equity: | ||||||||||||||||||
preferred stock, 0.001 par value; authorized shares – 10,000,000 at september 30, 2025 and december 31, 2024; no shares issued and outstanding at september 30, 2025 and december 31, 2024 | ||||||||||||||||||
common stock | 60,000 | 59,000 | 59,000 | 59,000 | 52,000 | 52,000 | 51,000 | 46,000 | 46,000 | 42,000 | 42,000 | 42,000 | 42,000 | 42,000 | 41,000 | 41,000 | 41,000 | 41,000 |
additional paid-in capital | 1,291,369,000 | 1,281,833,000 | 1,269,919,000 | 1,258,316,000 | 865,762,000 | 848,723,000 | 839,759,000 | 512,401,000 | 507,082,000 | 445,924,000 | 439,890,000 | 432,703,000 | 428,153,000 | 423,388,000 | 418,429,000 | 413,967,000 | 410,680,000 | 407,966,000 |
accumulated other comprehensive income | 4,562,000 | 3,747,000 | 3,756,000 | 2,163,000 | 7,831,000 | -1,616,000 | -524,000 | 665,000 | -270,000 | 24,000 | 17,000 | |||||||
accumulated deficit | -319,436,000 | -295,123,000 | -261,265,000 | -237,757,000 | -217,541,000 | -189,482,000 | -183,523,000 | -168,763,000 | -157,005,000 | -145,437,000 | -127,929,000 | -110,470,000 | -94,405,000 | -77,709,000 | -60,821,000 | -47,411,000 | -33,995,000 | -23,229,000 |
total stockholders’ equity | 976,555,000 | 990,516,000 | 1,012,469,000 | 1,022,781,000 | 656,104,000 | 657,677,000 | 655,763,000 | 344,349,000 | 348,948,000 | 299,469,000 | 311,264,000 | 320,740,000 | 331,513,000 | 343,814,000 | 356,082,000 | 366,327,000 | 376,750,000 | 384,795,000 |
total liabilities and stockholders’ equity | 1,024,766,000 | 1,032,212,000 | 1,050,772,000 | 1,061,516,000 | 695,019,000 | 691,412,000 | 688,984,000 | 380,407,000 | 386,850,000 | 341,500,000 | 352,956,000 | 364,010,000 | 375,756,000 | 385,365,000 | 368,597,000 | |||
preferred stock, 0.001 par value; authorized shares – 10,000,000 at june 30, 2025 and december 31, 2024; no shares issued and outstanding at june 30, 2025 and december 31, 2024 | ||||||||||||||||||
preferred stock, 0.001 par value; authorized shares – 10,000,000 at march 31, 2025 and december 31, 2024; no shares issued and outstanding at march 31, 2025 and december 31, 2024 | ||||||||||||||||||
current portion of deferred revenue | 94,000 | 972,000 | 1,705,000 | 3,648,000 | 5,340,000 | 4,935,000 | 5,406,000 | 5,906,000 | 5,371,000 | 4,649,000 | 5,163,000 | 5,264,000 | 5,065,000 | |||||
preferred stock, 0.001 par value; authorized shares – 10,000,000 at december 31, 2024 and 2023, respectively; no shares issued and outstanding at december 31, 2024 and 2023 | ||||||||||||||||||
preferred stock, 0.001 par value; authorized shares – 10,000,000 at september 30, 2024 and december 31, 2023, respectively; no shares issued and outstanding at september 30, 2024 and december 31, 2023 | ||||||||||||||||||
accounts receivable | 7,500,000 | 519,000 | 750,000 | 500,000 | 375,000 | |||||||||||||
preferred stock, 0.001 par value; authorized shares – 10,000,000 at june 30, 2024 and december 31, 2023, respectively; no shares issued and outstanding at june 30, 2024 and december 31, 2023 | ||||||||||||||||||
preferred stock, 0.001 par value; authorized shares – 10,000,000 at march 31, 2024 and december 31, 2023, respectively; no shares issued and outstanding at march 31, 2024 and december 31, 2023 | ||||||||||||||||||
deferred revenue, net of current portion | 307,000 | 1,394,000 | 2,221,000 | 3,816,000 | 5,289,000 | 700,000 | 1,840,000 | 2,823,000 | ||||||||||
preferred stock, 0.001 par value; authorized shares – 10,000,000 at december 31, 2023 and 2022, respectively; no shares issued and outstanding at december 31, 2023 and 2022 | ||||||||||||||||||
accrued liabilities | 6,831,000 | 9,216,000 | 7,737,000 | 8,010,000 | 7,240,000 | 4,043,000 | 5,074,000 | 3,779,000 | 2,030,000 | 2,286,000 | ||||||||
unvested stock liabilities | 25,000 | 30,000 | 35,000 | 169,000 | 323,000 | 492,000 | 700,000 | 1,203,000 | 1,352,000 | |||||||||
preferred stock, 0.001 par value; authorized shares – 10,000,000 at september 30, 2023 and december 31, 2022, respectively; no shares issued and outstanding at september 30, 2023 and december 31, 2022 | ||||||||||||||||||
accumulated other comprehensive loss | -1,175,000 | -1,060,000 | -739,000 | -1,535,000 | -2,277,000 | -1,907,000 | -1,567,000 | |||||||||||
preferred stock, 0.001 par value; authorized shares – 10,000,000 at june 30, 2023 and december 31, 2022, respectively; no shares issued and outstanding at june 30, 2023 and december 31, 2022 | ||||||||||||||||||
preferred stock, 0.001 par value; authorized shares – 10,000,000 at march 31, 2023 and december 31, 2022, respectively; no shares issued and outstanding at march 31, 2023 and december 31, 2022 | ||||||||||||||||||
preferred stock, 0.001 par value; authorized shares – 10,000,000 at december 31, 2022 and 2021, respectively; no shares issued and outstanding at december 31, 2022 and 2021 | ||||||||||||||||||
preferred stock, 0.001 par value; authorized shares – 10,000,000 at september 30, 2022 and december 31, 2021, respectively; no shares issued and outstanding at september 30, 2022 and december 31, 2021 | ||||||||||||||||||
preferred stock, 0.001 par value; authorized shares – 10,000,000 at june 30, 2022 and december 31, 2021, respectively; no shares issued and outstanding at june 30, 2022 and december 31, 2021 | ||||||||||||||||||
preferred stock, 0.001 par value; authorized shares – 10,000,000 at march 31, 2022 and december 31, 2021, respectively; no shares issued and outstanding at march 31, 2022 and december 31, 2021 | ||||||||||||||||||
liabilities, convertible preferred stock and stockholders’ equity | ||||||||||||||||||
convertible preferred stock, 0.001 par value; authorized shares – 0 and 6,838,829 at december 31, 2021 and 2020, respectively; issued and outstanding shares – 0 and 6,838,829 at december 31, 2021 and 2020, respectively; liquidation preference – 0 and 21,709 at december 31, 2021 and 2020, respectively | ||||||||||||||||||
stockholders’ equity | ||||||||||||||||||
preferred stock, 0.001 par value; authorized shares – 10,000,000 and 0 at december 31, 2021 and 2020, respectively; no shares issued and outstanding at december 31, 2021 and 2020 | ||||||||||||||||||
total liabilities, convertible preferred stock and stockholders’ equity | 379,824,000 | 391,084,000 | 396,823,000 | |||||||||||||||
convertible preferred stock, 0.001 par value; authorized shares – 0 and 6,838,829 at september 30, 2021 and december 31, 2020, respectively; issued and outstanding shares – 0 and 6,838,829 at september 30, 2021 and december 31, 2020, respectively; liquidation preference – 0 and 21,709 at september 30, 2021 and december 31, 2020, respectively | ||||||||||||||||||
preferred stock, 0.001 par value; authorized shares – 10,000,000 and 0 at september 30, 2021 and december 31, 2020, respectively; no shares issued and outstanding at september 30, 2021 and december 31, 2020 | ||||||||||||||||||
unvested stock liability | 1,500,000 | |||||||||||||||||
convertible preferred stock, 0.001 par value; authorized shares – 0 and 6,838,829 at june 30, 2021 and december 31, 2020, respectively; issued and outstanding shares – 0 and 6,838,829 at june 30, 2021 and december 31, 2020, respectively; liquidation preference – 0 and 21,709 at june 30, 2021 and december 31, 2020, respectively | ||||||||||||||||||
preferred stock, 0.001 par value; authorized shares – 10,000,000 and 0 at june 30, 2021 and december 31, 2020, respectively; no shares issued and outstanding at june 30, 2021 and december 31, 2020 |
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