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Ionis Pharmaceuticals Quarterly Income Statements Chart

Quarterly
 | 
Annual
 
 Revenue  
 Gross Profit  
 Operating Profit  
 Net Income  
20131231 20140331 20140630 20140930 20181231 20190331 20220331 20220630 20220930 20221231 20230331 20230630 20230930 20231231 20240331 20240630 20240930 20241231 20250331 20250630 -208.02-113.72-19.4374.87169.16263.46357.75452.05Milllion

Ionis Pharmaceuticals Quarterly Income Statements Table

Quarterly
 | 
Annual
 
Unit: USD2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2019-03-31 2018-12-31 2014-09-30 2014-06-30 2014-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31 2010-12-31 2010-09-30 2010-06-30 2010-03-31 2009-12-31 2009-09-30 2009-06-30 2009-03-31 2008-12-31 2008-09-30 2008-06-30 2008-03-31 2007-09-30 2007-06-30 2007-03-31 2006-12-31 2006-09-30 2006-06-30 2006-03-31 2005-09-30 2005-06-30 2005-03-31 2004-09-30 2004-06-30 2004-03-31 
                                                          
  revenue:                                                        
  commercial revenue:                                                        
  product sales19,273,000 6,287,000                                                       
  royalty revenue69,952,000 64,166,000                                                       
  other commercial revenue13,531,000 5,715,000 12,103,000 13,152,000 11,512,000 20,013,000 16,977,000 16,828,000 16,885,000                                                
  total commercial revenue102,756,000 76,168,000 85,716,000 75,731,000 72,036,000 59,593,000 78,845,000 84,081,000 77,897,000 67,768,000 80,479,000 72,410,000 78,184,000 72,285,000 68,088,000                                          
  research and development revenue:                                                        
  collaborative agreement revenue336,921,000 45,031,000 96,894,000 44,883,000 141,524,000 49,345,000 179,144,000 44,167,000 91,013,000 38,334,000 49,940,000 69,250,000 38,247,000 49,784,000                                           
  wainua joint development revenue12,372,000 10,413,000 43,966,000 13,200,000 11,690,000 10,559,000                                                   
  total research and development revenue349,293,000 55,444,000 140,860,000 58,083,000 153,214,000 59,904,000 245,660,000 60,126,000 110,514,000 62,756,000 71,410,000 87,357,000 55,607,000 69,634,000                                           
  total revenue452,049,000 131,612,000 226,576,000 133,814,000 225,250,000 119,497,000 324,505,000 144,207,000 188,411,000 130,524,000 151,889,000 159,767,000 133,791,000 141,919,000 297,214,000 32,325,000 44,063,000 57,076,000 28,161,000 42,249,000 23,585,000 38,092,000 43,360,000 19,873,000 11,601,000 47,340,000 23,235,000 32,403,000 20,713,000 24,823,000 21,147,000 26,420,000 28,624,000 23,503,000 29,926,000 32,262,000 26,771,000 30,992,000 31,576,000 20,661,000 32,215,000 32,961,000 21,354,000 38,631,000 3,813,000 2,450,000 11,945,000 3,253,000 4,375,000 4,958,000 7,458,000 105,929,843,000 7,442,000 9,093,000 9,843,000 12,303,000 
  yoy100.69% 10.14% -30.18% -7.21% 19.55% -8.45% 113.65% -9.74% 40.82% -8.03% -48.90% 394.25% 203.64% 148.65% 955.41% -23.49% 86.83% 49.84% -35.05% 112.59% 103.30% -19.54% 86.62% -38.67% -43.99% 90.71% 9.87% 22.65% -27.64% 5.62% -29.34% -18.11% 6.92% -24.16% -5.23% 56.15% -16.90% -5.97% 47.87% -46.52% 744.87% 1245.35% 78.77% 1087.55% -12.85% -50.58% 60.16% -100.00% -41.21% -45.47% -24.23% 860908.23%     
  qoq243.47% -41.91% 69.32% -40.59% 88.50% -63.18% 125.03% -23.46% 44.35% -14.07% -4.93% 19.42% -5.73% -52.25% 819.46% -26.64% -22.80% 102.68% -33.35% 79.14% -38.08% -12.15% 118.19% 71.30% -75.49% 103.74% -28.29% 56.44% -16.56% 17.38% -19.96% -7.70% 21.79% -21.46% -7.24% 20.51% -13.62% -1.85% 52.83% -35.87% -2.26% 54.36% -44.72% 913.14% 55.63% -79.49% 267.20% -25.65% -11.76% -33.52% -99.99% 1423305.58% -18.16% -7.62% -20.00%  
  expenses:                                                        
  cost of sales4,151,000 1,463,000 3,830,000 1,071,000 4,164,000 2,151,000 3,062,000 2,191,000 2,537,000 1,343,000 3,686,000 1,515,000 4,745,000 4,170,000                                           
  gross profit447,898,000 130,149,000 222,746,000 132,743,000 221,086,000 117,346,000 321,443,000 142,016,000 185,874,000 129,181,000 148,203,000 158,252,000 129,046,000 137,749,000                                           
  yoy102.59% 10.91% -30.70% -6.53% 18.94% -9.16% 116.89% -10.26% 44.04% -6.22%                                               
  qoq244.14% -41.57% 67.80% -39.96% 88.41% -63.49% 126.34% -23.60% 43.89% -12.84% -6.35% 22.63% -6.32%                                            
  gross margin %99.08% 98.89% 98.31% 99.20% 98.15% 98.20% 99.06% 98.48% 98.65% 98.97% 97.57% 99.05% 96.45% 97.06% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 
  research, development and patent217,460,000 200,759,000 245,490,000 219,761,000 222,064,000 214,215,000 256,555,000 215,330,000 229,927,000 197,813,000 308,272,000 182,990,000 180,758,000 161,126,000 106,417,000                                          
  selling, general and administrative90,622,000 76,250,000 88,079,000 61,638,000 65,113,000 52,644,000 71,011,000 69,951,000 46,142,000 45,516,000 47,950,000 34,416,000 33,802,000 34,127,000 68,221,000                         3,301,500 4,571,000 4,899,000 3,736,000 4,278,000 3,089,000 3,402,000 4,520,000 2,823,000         
  total operating expenses312,233,000 278,472,000 337,399,000 282,470,000 291,341,000 269,010,000 330,628,000 287,472,000 278,606,000 244,672,000 359,908,000 218,921,000 219,305,000 199,423,000 175,679,000 46,777,750 65,556,000 63,726,000 57,828,000 62,107,000 49,090,000 46,020,000 41,735,000 45,992,000 39,647,000 43,644,000 41,690,000 51,019,000 43,029,000 38,883,000 37,255,000 42,278,000 37,571,000 42,175,000 34,806,000 43,933,000 37,167,000 35,819,000 32,218,000 17,433,000 36,539,000 36,094,000 30,185,000 28,574,000 23,473,000 23,351,000 28,681,000 21,517,000 21,477,000 20,974,000 19,602,000 2,351,531,183,000 30,949,000 31,473,000 31,183,000 34,638,000 
  income from operations139,816,000 -146,860,000 -110,823,000 -148,656,000 -66,091,000 -149,513,000 -6,123,000 -143,265,000 -90,195,000 -114,148,000 -208,019,000 -59,154,000 -85,514,000 -57,504,000 121,535,000 -14,452,750 -21,493,000 -6,650,000 -29,667,000    1,625,000   3,696,000                  10,057,000             
  yoy-311.55% -1.77% 1709.95% 3.76% -26.72% 30.98% -97.06% 142.19% 5.47% 98.50% -271.16% 309.29% 297.87% 764.72% -509.66%    -1925.66%                                      
  qoq-195.20% 32.52% -25.45% 124.93% -55.80% 2341.83% -95.73% 58.84% -20.98% -45.13% 251.66% -30.83% 48.71% -147.31% -940.91% -32.76% 223.20% -77.58%                                       
  operating margin %30.93% -111.59% -48.91% -111.09% -29.34% -125.12% -1.89% -99.35% -47.87% -87.45% -136.95% -37.03% -63.92% -40.52% 40.89% -44.71% -48.78% -11.65% -105.35% 0%   3.75% 0%  7.81%  0%    0%    0%    0%    26.03%   0%          
  other income:                                                        
  investment income24,687,000 24,667,000 28,910,000 26,228,000 25,599,000 26,285,000 25,686,000 23,935,000 20,792,000 18,627,000 11,884,000 7,524,000 3,403,000 1,993,000 12,142,000 500,750 675,000 671,000 657,000 685,000 434,000 589,000 376,000 359,000 408,000 477,000 600,000 518,000 575,000 616,000 705,000 780,000 776,000 859,000 955,000 1,118,000 1,430,000 1,678,000 2,192,000 -1,743,000 7,546,000 560,000 4,956,000 2,603,000 3,053,000 3,401,000 2,123,000 1,682,000 1,344,000 811,000 1,241,000 349,842,000 504,000 561,000 842,000 1,133,000 
  interest expense -4,108,000 -4,191,000 -4,161,000 -4,490,000 -4,151,000 -4,558,000 -4,203,000 -2,291,000 -1,608,000 -1,731,000 -2,139,000 -2,130,000 -2,122,000 -11,599,000 -3,725,500 -4,998,000 -4,961,000 -4,943,000                                      
  interest expense related to sale of future royalties -18,822,000 -18,669,000 -18,533,000 -18,296,000 -17,959,000 -17,849,000 -17,779,000 -17,655,000 -15,515,000                                               
  loss on investments         -529,000    -6,625,000                                           
  other income102,000 465,000 314,000 142,000 610,000 277,000 399,000 2,447,000 11,183,000 230,000 -1,980,750 4,713,000 -12,297,000 187,000                                           
  income before income tax benefit123,531,000  -107,039,000 -144,101,000       -44,330,000 -46,709,000    -17,508,750 -25,278,000  -33,556,000                                      
  income tax benefit20,000  2,690,000 3,621,000       -8,100,000 -283,000    -500 -1,398,000 -881,000 2,276,000 -523,000 5,193,000 1,181,000 64,000 8,405,000 706,000           1,156,250 3,968,000  717,000                  
  net income123,551,000 -146,938,000 -104,349,000 -140,480,000 -66,265,000 -142,803,000 -9,263,000 -147,410,000 -85,290,000 -124,323,000 -52,430,000 -46,992,000 -105,135,000 -65,165,000 90,884,000 -17,509,250 -26,676,000 -12,081,000 -31,280,000 -24,276,000 -24,570,000 -10,126,000 -1,672,000 -2,637,000 -37,639,000 -1,207,000 -23,995,000 -16,191,250 -26,882,000 -17,889,000 -19,994,000     -8,445,000   170,930,000  3,188,000   20,007,000             
  yoy-286.45% 2.90% 1026.51% -4.70% -22.31% 14.86% -82.33% 213.69% -18.88% 90.78% -157.69% 168.38% 294.12% 439.40% -390.55% -27.87% 8.57% 19.31% 1770.81% 820.59% -34.72% 738.94% -93.03% -83.71% 40.02% -93.25% 20.01%                              
  qoq-184.08% 40.81% -25.72% 112.00% -53.60% 1441.65% -93.72% 72.83% -31.40% 137.12% 11.57% -55.30% 61.34% -171.70% -619.06% -34.36% 120.81% -61.38% 28.85% -1.20% 142.64% 505.62% -36.59% -92.99% 3018.39% -94.97% 48.20% -39.77% 50.27% -10.53%                           
  net income margin %27.33% -111.64% -46.05% -104.98% -29.42% -119.50% -2.85% -102.22% -45.27% -95.25% -34.52% -29.41% -78.58% -45.92% 30.58% -54.17% -60.54% -21.17% -111.08% -57.46% -104.18% -26.58% -3.86% -13.27% -324.45% -2.55% -103.27% -49.97% -129.78% -72.07% -94.55% 0%    -26.18%   541.33% 0% 9.90% 0% 0% 51.79% 0% 0% 0% 0% 0% 0%       
  basic net income per share0.78              0.63                                          
  diluted net income per share0.7              0.62                                          
  shares used in computing basic net income per share159,137              138,582                     24,497 98,320 98,116 97,521 23,446.5 95,863                
  shares used in computing diluted net income per share182,331              141,537                     24,497 98,320 98,116 111,274 23,446.5 100,181                
  gain on investments -2,164,000 -80,250 879,000 -3,533,000 2,333,000 -161,000 -1,943,000 718,000  3,283,000 2,347,000 -6,337,000   168,750 538,000 -260,000 397,000 305,000 175,000 840,000 1,058,000 1,446,000  2,000 17,000  18,000 34,000      -710,000 123,000 2,612,000       1,989,000 1,521,000   2,263,000        
  income before income tax expense -146,822,000   -66,201,000 -142,728,000 -82,799,500 -140,808,000 -77,448,000 -112,943,000   -102,875,000 -64,071,000 121,931,000   -11,200,000                                       
  income tax expense -116,000   -64,000 -75,000 -6,456,250 -6,602,000 -7,842,000 -11,380,000   -2,260,000 -1,094,000 -31,047,000                                          
  basic and diluted net income per share -0.93 -0.66 -0.95 -0.45 -0.98 -0.06 -1.03 -0.6 -0.87 -0.37 -0.33 -0.74 -0.46  -0.15 -0.23 -0.1 -0.27 -0.22 -0.21 -0.09 -0.02 -0.02 -0.37 -0.01 -0.24 -0.163 -0.27 -0.18          -0.01 0.03 -0.02 -0.05 -1.25 -0.13 -0.16 -0.18 -0.16 -0.03 -0.24 -0.24  -0.52 -0.57 -0.47 -0.47 
  shares used in computing basic and diluted net income per share 158,735 2,811 148,593 145,958 145,538 138 143,317 143,098 142,735 66 141,950 141,794 141,599  29,377.75 117,811 117,588 117,128 1,894 115,263 108,539 101,875 225 100,680 100,213 100,157 36 99,687 99,602 99,569 42 99,196 99,091 99,013       94,675 90,799 83,942 82,548 82,456 1,374 73,588 72,822 72,377 64,086 5,752,456,111 57,521 57,267 56,111 55,858 
  spinraza royalties  63,684,000 57,208,000 56,743,000 38,455,000 61,868,000 67,253,000 61,012,000 50,247,000 67,222,000 61,647,000 59,627,000 53,818,000 59,711,000                                          
  wainua royalties  9,929,000 5,371,000 3,781,000 1,125,000                                                   
  eplontersen joint development revenue      14,970,750 15,959,000 19,501,000 24,422,000 21,470,000 18,107,000 17,360,000 19,850,000                                           
  tegsedi and waylivra revenue         6,478,000 7,584,000 5,920,000 10,386,000 6,160,000                                           
  licensing and other royalty revenue         11,043,000 5,673,000 4,843,000 8,171,000 12,307,000 1,623,000                                          
  tegsedi product sales              6,754,000                                          
  research and development revenue under collaborative agreements              229,126,000 29,993,750 43,798,000 56,628,000 19,550,000 41,276,000 23,383,000 37,615,000 41,921,000 19,015,000 11,127,000 47,140,000 21,818,000 31,682,000 20,189,000 24,305,000 20,014,000 25,437,000 27,785,000 21,143,000 28,556,000 21,716,000 25,962,000 30,768,000 29,685,000 20,114,000 31,240,000 26,814,000 20,686,000 11,921,000 3,482,000 2,002,000 3,831,000 2,469,000 4,322,000 4,468,000 7,122,000 104,388,217,000 7,135,000 9,055,000 8,217,000 6,998,000 
  cost of products sold              1,041,000                                          
  other incomes              -147,000                                          
  net (income) loss attributable to noncontrolling interest in akcea therapeutics, inc.              -6,441,000                                          
  net income attributable to ionis pharmaceuticals, inc. common stockholders              84,443,000                                          
  licensing and royalty revenue               2,331,250 265,000 448,000 8,611,000 973,000 202,000 477,000 1,439,000 858,000 474,000 200,000 1,417,000 721,000 524,000 518,000 1,133,000 983,000 839,000 2,360,000 1,370,000 10,546,000 809,000 224,000 1,891,000 547,000 975,000 6,147,000 668,000 26,710,000 331,000 448,000 8,114,000 784,000 53,000 490,000 336,000 1,541,626,000 307,000 38,000 1,626,000 5,305,000 
  research, development and patent expenses               240,802,000 61,086,000 59,264,000 53,448,000 57,430,000 45,660,000                                    
  general and administrative               3,328,250 4,470,000 4,462,000 4,380,000 4,677,000 3,430,000 3,389,000 3,423,000 3,234,000 3,096,000 3,209,000 2,976,000 3,800,000 3,105,000 2,874,000 3,010,000 2,945,000 2,855,000 3,051,000 2,819,000 3,830,000 3,335,000 3,673,000 3,677,000          2,710,000 2,566,000 1,724,000 19,102,568,000 2,137,000 2,373,000 2,568,000 2,453,000 
  equity in net income of regulus therapeutics inc.                                                        
  loss on early retirement of debt                                                        
  research and development                     42,631,000 38,312,000 42,758,000 36,551,000 40,435,000 38,714,000 47,219,000 39,924,000 36,009,000 34,245,000 39,333,000 34,716,000 39,124,000 31,987,000 40,103,000 33,832,000 32,146,000 28,541,000 16,828,000 31,968,000 31,195,000 26,449,000 24,296,000 20,384,000 19,949,000 24,240,000 18,973,000 18,982,000 18,372,000 18,212,000 2,095,032,036,000 22,361,000 29,566,000 32,036,000 28,947,000 
  basic and diluted net income                              -200                          
  income from continuing operations, before income tax expense                                                        
  net income from continuing operations                                   -0.21 -0.07 -0.03                   
  discontinued operations:                                                        
  income from discontinued operations                                                        
  gain on sale of ibis biosciences, inc., net of tax                                   13,884,000   171,773,000                  
  net income from discontinued operations, net of tax                                   13,884,000   171,744,000                  
  net income attributable to noncontrolling interest in regulus therapeutics inc.                                   1,487,000 1,136,000 857,000 913,000                  
  net income attributable to isis pharmaceuticals, inc. common stockholders                               -13,986,000 -12,454,000 -25,154,000 -9,658,000 -6,958,000 -6,924,000 -2,896,000 171,843,000                  
  basic and diluted net income per share:                                                        
  net income from continuing operations attributable to isis pharmaceuticals, inc. common stockholders                               -0.14 -0.13 -0.25 -0.1                      
  net income from discontinued operations                                   0.14   1.76                  
  basic and diluted net income attributable to isis pharmaceuticals, inc. common stockholders                               -0.14 -0.13 -0.25 -0.1 -0.07 -0.07                    
  income from continuing operations, before income tax benefit                                                        
  net income from continuing operations, net of income tax benefit                                                        
  basic net income per share:                                                        
  basic net income attributable to isis pharmaceuticals, inc. common stockholders                                     -0.03 1.76                  
  diluted net income per share:                                                        
  diluted net income attributable to isis pharmaceuticals, inc. common stockholders                                     -0.03 1.57                  
  loss attributed to noncontrolling interest in symphony genisis, inc.                                           8,748,000 7,603,000 6,806,000 5,085,250 6,733,000 13,608,000        
  loss attributed to noncontrolling interest in regulus therapeutics llc                                       764,000 1,208,000 965,000 883,000 87,000             
  loss attributed to noncontrolling interest in ibis biosciences, inc.                                       290,750 267,000 791,000 105,000              
  excess purchase price over carrying value of noncontrolling interest in symphony genisis, inc.                                                        
  net income applicable to common stock                                       -8,658,000 3,188,000 -2,208,000 -4,285,000 -105,304,000 -11,024,000 -13,020,000 -14,146,000 -12,105,000 -2,172,000 -17,480,000 -15,172,000  -29,658,000 -32,708,000 -26,129,000 -26,487,000 
  restructuring activities                                                 36,000  650,000 7,084,000    
  net income before noncontrolling interest in symphony genisis, inc.                                                        
  operating expenses:                                                        
  compensation expense/(benefit) related to variable accounting of stock options                                                        
  compensation benefit related to variable accounting of stock options                                                        
  compensation benefit related to stock options                                                  15,000 5,000     
  accretion of dividends on preferred stock                                                        
  compensation expense related to stock options                                                       3,238,000 

We provide you with 20 years income statements for Ionis Pharmaceuticals stock, allowing you to gain comprehensive visibility into the fundamentals of the company. Our detailed breakdowns include key financial metrics such as earnings, sales and marketing expenses, research and development costs, profits, and profit margins. This in-depth information is essential for making informed investment decisions and understanding the financial health and performance of Ionis Pharmaceuticals stock. Explore the full financial landscape of Ionis Pharmaceuticals stock with our expertly curated income statements.

The information provided in this report about Ionis Pharmaceuticals stock is taken from www.sec.gov and many other data providers. While we have conducted our best efforts to ensure that the parsed data is accurate, we cannot guarantee its accuracy. Please use caution and understand that any consequences of its use are your own responsibility.