Ionis Pharmaceuticals Quarterly Income Statements Chart
Quarterly
|
Annual
Ionis Pharmaceuticals Quarterly Income Statements Table
Quarterly
|
Annual
Unit: USD | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2019-03-31 | 2018-12-31 | 2014-09-30 | 2014-06-30 | 2014-03-31 | 2013-12-31 | 2013-09-30 | 2013-06-30 | 2013-03-31 | 2012-12-31 | 2012-09-30 | 2012-06-30 | 2012-03-31 | 2011-12-31 | 2011-09-30 | 2011-06-30 | 2011-03-31 | 2010-12-31 | 2010-09-30 | 2010-06-30 | 2010-03-31 | 2009-12-31 | 2009-09-30 | 2009-06-30 | 2009-03-31 | 2008-12-31 | 2008-09-30 | 2008-06-30 | 2008-03-31 | 2007-09-30 | 2007-06-30 | 2007-03-31 | 2006-12-31 | 2006-09-30 | 2006-06-30 | 2006-03-31 | 2005-09-30 | 2005-06-30 | 2005-03-31 | 2004-09-30 | 2004-06-30 | 2004-03-31 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
revenue: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
commercial revenue: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
product sales | 19,273,000 | 6,287,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
royalty revenue | 69,952,000 | 64,166,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
other commercial revenue | 13,531,000 | 5,715,000 | 12,103,000 | 13,152,000 | 11,512,000 | 20,013,000 | 16,977,000 | 16,828,000 | 16,885,000 | |||||||||||||||||||||||||||||||||||||||||||||||
total commercial revenue | 102,756,000 | 76,168,000 | 85,716,000 | 75,731,000 | 72,036,000 | 59,593,000 | 78,845,000 | 84,081,000 | 77,897,000 | 67,768,000 | 80,479,000 | 72,410,000 | 78,184,000 | 72,285,000 | 68,088,000 | |||||||||||||||||||||||||||||||||||||||||
research and development revenue: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
collaborative agreement revenue | 336,921,000 | 45,031,000 | 96,894,000 | 44,883,000 | 141,524,000 | 49,345,000 | 179,144,000 | 44,167,000 | 91,013,000 | 38,334,000 | 49,940,000 | 69,250,000 | 38,247,000 | 49,784,000 | ||||||||||||||||||||||||||||||||||||||||||
wainua joint development revenue | 12,372,000 | 10,413,000 | 43,966,000 | 13,200,000 | 11,690,000 | 10,559,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||
total research and development revenue | 349,293,000 | 55,444,000 | 140,860,000 | 58,083,000 | 153,214,000 | 59,904,000 | 245,660,000 | 60,126,000 | 110,514,000 | 62,756,000 | 71,410,000 | 87,357,000 | 55,607,000 | 69,634,000 | ||||||||||||||||||||||||||||||||||||||||||
total revenue | 452,049,000 | 131,612,000 | 226,576,000 | 133,814,000 | 225,250,000 | 119,497,000 | 324,505,000 | 144,207,000 | 188,411,000 | 130,524,000 | 151,889,000 | 159,767,000 | 133,791,000 | 141,919,000 | 297,214,000 | 32,325,000 | 44,063,000 | 57,076,000 | 28,161,000 | 42,249,000 | 23,585,000 | 38,092,000 | 43,360,000 | 19,873,000 | 11,601,000 | 47,340,000 | 23,235,000 | 32,403,000 | 20,713,000 | 24,823,000 | 21,147,000 | 26,420,000 | 28,624,000 | 23,503,000 | 29,926,000 | 32,262,000 | 26,771,000 | 30,992,000 | 31,576,000 | 20,661,000 | 32,215,000 | 32,961,000 | 21,354,000 | 38,631,000 | 3,813,000 | 2,450,000 | 11,945,000 | 3,253,000 | 4,375,000 | 4,958,000 | 7,458,000 | 105,929,843,000 | 7,442,000 | 9,093,000 | 9,843,000 | 12,303,000 |
yoy | 100.69% | 10.14% | -30.18% | -7.21% | 19.55% | -8.45% | 113.65% | -9.74% | 40.82% | -8.03% | -48.90% | 394.25% | 203.64% | 148.65% | 955.41% | -23.49% | 86.83% | 49.84% | -35.05% | 112.59% | 103.30% | -19.54% | 86.62% | -38.67% | -43.99% | 90.71% | 9.87% | 22.65% | -27.64% | 5.62% | -29.34% | -18.11% | 6.92% | -24.16% | -5.23% | 56.15% | -16.90% | -5.97% | 47.87% | -46.52% | 744.87% | 1245.35% | 78.77% | 1087.55% | -12.85% | -50.58% | 60.16% | -100.00% | -41.21% | -45.47% | -24.23% | 860908.23% | ||||
qoq | 243.47% | -41.91% | 69.32% | -40.59% | 88.50% | -63.18% | 125.03% | -23.46% | 44.35% | -14.07% | -4.93% | 19.42% | -5.73% | -52.25% | 819.46% | -26.64% | -22.80% | 102.68% | -33.35% | 79.14% | -38.08% | -12.15% | 118.19% | 71.30% | -75.49% | 103.74% | -28.29% | 56.44% | -16.56% | 17.38% | -19.96% | -7.70% | 21.79% | -21.46% | -7.24% | 20.51% | -13.62% | -1.85% | 52.83% | -35.87% | -2.26% | 54.36% | -44.72% | 913.14% | 55.63% | -79.49% | 267.20% | -25.65% | -11.76% | -33.52% | -99.99% | 1423305.58% | -18.16% | -7.62% | -20.00% | |
expenses: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cost of sales | 4,151,000 | 1,463,000 | 3,830,000 | 1,071,000 | 4,164,000 | 2,151,000 | 3,062,000 | 2,191,000 | 2,537,000 | 1,343,000 | 3,686,000 | 1,515,000 | 4,745,000 | 4,170,000 | ||||||||||||||||||||||||||||||||||||||||||
gross profit | 447,898,000 | 130,149,000 | 222,746,000 | 132,743,000 | 221,086,000 | 117,346,000 | 321,443,000 | 142,016,000 | 185,874,000 | 129,181,000 | 148,203,000 | 158,252,000 | 129,046,000 | 137,749,000 | ||||||||||||||||||||||||||||||||||||||||||
yoy | 102.59% | 10.91% | -30.70% | -6.53% | 18.94% | -9.16% | 116.89% | -10.26% | 44.04% | -6.22% | ||||||||||||||||||||||||||||||||||||||||||||||
qoq | 244.14% | -41.57% | 67.80% | -39.96% | 88.41% | -63.49% | 126.34% | -23.60% | 43.89% | -12.84% | -6.35% | 22.63% | -6.32% | |||||||||||||||||||||||||||||||||||||||||||
gross margin % | 99.08% | 98.89% | 98.31% | 99.20% | 98.15% | 98.20% | 99.06% | 98.48% | 98.65% | 98.97% | 97.57% | 99.05% | 96.45% | 97.06% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% |
research, development and patent | 217,460,000 | 200,759,000 | 245,490,000 | 219,761,000 | 222,064,000 | 214,215,000 | 256,555,000 | 215,330,000 | 229,927,000 | 197,813,000 | 308,272,000 | 182,990,000 | 180,758,000 | 161,126,000 | 106,417,000 | |||||||||||||||||||||||||||||||||||||||||
selling, general and administrative | 90,622,000 | 76,250,000 | 88,079,000 | 61,638,000 | 65,113,000 | 52,644,000 | 71,011,000 | 69,951,000 | 46,142,000 | 45,516,000 | 47,950,000 | 34,416,000 | 33,802,000 | 34,127,000 | 68,221,000 | 3,301,500 | 4,571,000 | 4,899,000 | 3,736,000 | 4,278,000 | 3,089,000 | 3,402,000 | 4,520,000 | 2,823,000 | ||||||||||||||||||||||||||||||||
total operating expenses | 312,233,000 | 278,472,000 | 337,399,000 | 282,470,000 | 291,341,000 | 269,010,000 | 330,628,000 | 287,472,000 | 278,606,000 | 244,672,000 | 359,908,000 | 218,921,000 | 219,305,000 | 199,423,000 | 175,679,000 | 46,777,750 | 65,556,000 | 63,726,000 | 57,828,000 | 62,107,000 | 49,090,000 | 46,020,000 | 41,735,000 | 45,992,000 | 39,647,000 | 43,644,000 | 41,690,000 | 51,019,000 | 43,029,000 | 38,883,000 | 37,255,000 | 42,278,000 | 37,571,000 | 42,175,000 | 34,806,000 | 43,933,000 | 37,167,000 | 35,819,000 | 32,218,000 | 17,433,000 | 36,539,000 | 36,094,000 | 30,185,000 | 28,574,000 | 23,473,000 | 23,351,000 | 28,681,000 | 21,517,000 | 21,477,000 | 20,974,000 | 19,602,000 | 2,351,531,183,000 | 30,949,000 | 31,473,000 | 31,183,000 | 34,638,000 |
income from operations | 139,816,000 | -146,860,000 | -110,823,000 | -148,656,000 | -66,091,000 | -149,513,000 | -6,123,000 | -143,265,000 | -90,195,000 | -114,148,000 | -208,019,000 | -59,154,000 | -85,514,000 | -57,504,000 | 121,535,000 | -14,452,750 | -21,493,000 | -6,650,000 | -29,667,000 | 1,625,000 | 3,696,000 | 10,057,000 | ||||||||||||||||||||||||||||||||||
yoy | -311.55% | -1.77% | 1709.95% | 3.76% | -26.72% | 30.98% | -97.06% | 142.19% | 5.47% | 98.50% | -271.16% | 309.29% | 297.87% | 764.72% | -509.66% | -1925.66% | ||||||||||||||||||||||||||||||||||||||||
qoq | -195.20% | 32.52% | -25.45% | 124.93% | -55.80% | 2341.83% | -95.73% | 58.84% | -20.98% | -45.13% | 251.66% | -30.83% | 48.71% | -147.31% | -940.91% | -32.76% | 223.20% | -77.58% | ||||||||||||||||||||||||||||||||||||||
operating margin % | 30.93% | -111.59% | -48.91% | -111.09% | -29.34% | -125.12% | -1.89% | -99.35% | -47.87% | -87.45% | -136.95% | -37.03% | -63.92% | -40.52% | 40.89% | -44.71% | -48.78% | -11.65% | -105.35% | 0% | 3.75% | 0% | 7.81% | 0% | 0% | 0% | 0% | 26.03% | 0% | |||||||||||||||||||||||||||
other income: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
investment income | 24,687,000 | 24,667,000 | 28,910,000 | 26,228,000 | 25,599,000 | 26,285,000 | 25,686,000 | 23,935,000 | 20,792,000 | 18,627,000 | 11,884,000 | 7,524,000 | 3,403,000 | 1,993,000 | 12,142,000 | 500,750 | 675,000 | 671,000 | 657,000 | 685,000 | 434,000 | 589,000 | 376,000 | 359,000 | 408,000 | 477,000 | 600,000 | 518,000 | 575,000 | 616,000 | 705,000 | 780,000 | 776,000 | 859,000 | 955,000 | 1,118,000 | 1,430,000 | 1,678,000 | 2,192,000 | -1,743,000 | 7,546,000 | 560,000 | 4,956,000 | 2,603,000 | 3,053,000 | 3,401,000 | 2,123,000 | 1,682,000 | 1,344,000 | 811,000 | 1,241,000 | 349,842,000 | 504,000 | 561,000 | 842,000 | 1,133,000 |
interest expense | -4,108,000 | -4,191,000 | -4,161,000 | -4,490,000 | -4,151,000 | -4,558,000 | -4,203,000 | -2,291,000 | -1,608,000 | -1,731,000 | -2,139,000 | -2,130,000 | -2,122,000 | -11,599,000 | -3,725,500 | -4,998,000 | -4,961,000 | -4,943,000 | ||||||||||||||||||||||||||||||||||||||
interest expense related to sale of future royalties | -18,822,000 | -18,669,000 | -18,533,000 | -18,296,000 | -17,959,000 | -17,849,000 | -17,779,000 | -17,655,000 | -15,515,000 | |||||||||||||||||||||||||||||||||||||||||||||||
loss on investments | -529,000 | -6,625,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
other income | 102,000 | 465,000 | 314,000 | 142,000 | 610,000 | 277,000 | 399,000 | 2,447,000 | 11,183,000 | 230,000 | -1,980,750 | 4,713,000 | -12,297,000 | 187,000 | ||||||||||||||||||||||||||||||||||||||||||
income before income tax benefit | 123,531,000 | -107,039,000 | -144,101,000 | -44,330,000 | -46,709,000 | -17,508,750 | -25,278,000 | -33,556,000 | ||||||||||||||||||||||||||||||||||||||||||||||||
income tax benefit | 20,000 | 2,690,000 | 3,621,000 | -8,100,000 | -283,000 | -500 | -1,398,000 | -881,000 | 2,276,000 | -523,000 | 5,193,000 | 1,181,000 | 64,000 | 8,405,000 | 706,000 | 1,156,250 | 3,968,000 | 717,000 | ||||||||||||||||||||||||||||||||||||||
net income | 123,551,000 | -146,938,000 | -104,349,000 | -140,480,000 | -66,265,000 | -142,803,000 | -9,263,000 | -147,410,000 | -85,290,000 | -124,323,000 | -52,430,000 | -46,992,000 | -105,135,000 | -65,165,000 | 90,884,000 | -17,509,250 | -26,676,000 | -12,081,000 | -31,280,000 | -24,276,000 | -24,570,000 | -10,126,000 | -1,672,000 | -2,637,000 | -37,639,000 | -1,207,000 | -23,995,000 | -16,191,250 | -26,882,000 | -17,889,000 | -19,994,000 | -8,445,000 | 170,930,000 | 3,188,000 | 20,007,000 | |||||||||||||||||||||
yoy | -286.45% | 2.90% | 1026.51% | -4.70% | -22.31% | 14.86% | -82.33% | 213.69% | -18.88% | 90.78% | -157.69% | 168.38% | 294.12% | 439.40% | -390.55% | -27.87% | 8.57% | 19.31% | 1770.81% | 820.59% | -34.72% | 738.94% | -93.03% | -83.71% | 40.02% | -93.25% | 20.01% | |||||||||||||||||||||||||||||
qoq | -184.08% | 40.81% | -25.72% | 112.00% | -53.60% | 1441.65% | -93.72% | 72.83% | -31.40% | 137.12% | 11.57% | -55.30% | 61.34% | -171.70% | -619.06% | -34.36% | 120.81% | -61.38% | 28.85% | -1.20% | 142.64% | 505.62% | -36.59% | -92.99% | 3018.39% | -94.97% | 48.20% | -39.77% | 50.27% | -10.53% | ||||||||||||||||||||||||||
net income margin % | 27.33% | -111.64% | -46.05% | -104.98% | -29.42% | -119.50% | -2.85% | -102.22% | -45.27% | -95.25% | -34.52% | -29.41% | -78.58% | -45.92% | 30.58% | -54.17% | -60.54% | -21.17% | -111.08% | -57.46% | -104.18% | -26.58% | -3.86% | -13.27% | -324.45% | -2.55% | -103.27% | -49.97% | -129.78% | -72.07% | -94.55% | 0% | -26.18% | 541.33% | 0% | 9.90% | 0% | 0% | 51.79% | 0% | 0% | 0% | 0% | 0% | 0% | |||||||||||
basic net income per share | 0.78 | 0.63 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
diluted net income per share | 0.7 | 0.62 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
shares used in computing basic net income per share | 159,137 | 138,582 | 24,497 | 98,320 | 98,116 | 97,521 | 23,446.5 | 95,863 | ||||||||||||||||||||||||||||||||||||||||||||||||
shares used in computing diluted net income per share | 182,331 | 141,537 | 24,497 | 98,320 | 98,116 | 111,274 | 23,446.5 | 100,181 | ||||||||||||||||||||||||||||||||||||||||||||||||
gain on investments | -2,164,000 | -80,250 | 879,000 | -3,533,000 | 2,333,000 | -161,000 | -1,943,000 | 718,000 | 3,283,000 | 2,347,000 | -6,337,000 | 168,750 | 538,000 | -260,000 | 397,000 | 305,000 | 175,000 | 840,000 | 1,058,000 | 1,446,000 | 2,000 | 17,000 | 18,000 | 34,000 | -710,000 | 123,000 | 2,612,000 | 1,989,000 | 1,521,000 | 2,263,000 | ||||||||||||||||||||||||||
income before income tax expense | -146,822,000 | -66,201,000 | -142,728,000 | -82,799,500 | -140,808,000 | -77,448,000 | -112,943,000 | -102,875,000 | -64,071,000 | 121,931,000 | -11,200,000 | |||||||||||||||||||||||||||||||||||||||||||||
income tax expense | -116,000 | -64,000 | -75,000 | -6,456,250 | -6,602,000 | -7,842,000 | -11,380,000 | -2,260,000 | -1,094,000 | -31,047,000 | ||||||||||||||||||||||||||||||||||||||||||||||
basic and diluted net income per share | -0.93 | -0.66 | -0.95 | -0.45 | -0.98 | -0.06 | -1.03 | -0.6 | -0.87 | -0.37 | -0.33 | -0.74 | -0.46 | -0.15 | -0.23 | -0.1 | -0.27 | -0.22 | -0.21 | -0.09 | -0.02 | -0.02 | -0.37 | -0.01 | -0.24 | -0.163 | -0.27 | -0.18 | -0.01 | 0.03 | -0.02 | -0.05 | -1.25 | -0.13 | -0.16 | -0.18 | -0.16 | -0.03 | -0.24 | -0.24 | -0.52 | -0.57 | -0.47 | -0.47 | ||||||||||||
shares used in computing basic and diluted net income per share | 158,735 | 2,811 | 148,593 | 145,958 | 145,538 | 138 | 143,317 | 143,098 | 142,735 | 66 | 141,950 | 141,794 | 141,599 | 29,377.75 | 117,811 | 117,588 | 117,128 | 1,894 | 115,263 | 108,539 | 101,875 | 225 | 100,680 | 100,213 | 100,157 | 36 | 99,687 | 99,602 | 99,569 | 42 | 99,196 | 99,091 | 99,013 | 94,675 | 90,799 | 83,942 | 82,548 | 82,456 | 1,374 | 73,588 | 72,822 | 72,377 | 64,086 | 5,752,456,111 | 57,521 | 57,267 | 56,111 | 55,858 | ||||||||
spinraza royalties | 63,684,000 | 57,208,000 | 56,743,000 | 38,455,000 | 61,868,000 | 67,253,000 | 61,012,000 | 50,247,000 | 67,222,000 | 61,647,000 | 59,627,000 | 53,818,000 | 59,711,000 | |||||||||||||||||||||||||||||||||||||||||||
wainua royalties | 9,929,000 | 5,371,000 | 3,781,000 | 1,125,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
eplontersen joint development revenue | 14,970,750 | 15,959,000 | 19,501,000 | 24,422,000 | 21,470,000 | 18,107,000 | 17,360,000 | 19,850,000 | ||||||||||||||||||||||||||||||||||||||||||||||||
tegsedi and waylivra revenue | 6,478,000 | 7,584,000 | 5,920,000 | 10,386,000 | 6,160,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||
licensing and other royalty revenue | 11,043,000 | 5,673,000 | 4,843,000 | 8,171,000 | 12,307,000 | 1,623,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||
tegsedi product sales | 6,754,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
research and development revenue under collaborative agreements | 229,126,000 | 29,993,750 | 43,798,000 | 56,628,000 | 19,550,000 | 41,276,000 | 23,383,000 | 37,615,000 | 41,921,000 | 19,015,000 | 11,127,000 | 47,140,000 | 21,818,000 | 31,682,000 | 20,189,000 | 24,305,000 | 20,014,000 | 25,437,000 | 27,785,000 | 21,143,000 | 28,556,000 | 21,716,000 | 25,962,000 | 30,768,000 | 29,685,000 | 20,114,000 | 31,240,000 | 26,814,000 | 20,686,000 | 11,921,000 | 3,482,000 | 2,002,000 | 3,831,000 | 2,469,000 | 4,322,000 | 4,468,000 | 7,122,000 | 104,388,217,000 | 7,135,000 | 9,055,000 | 8,217,000 | 6,998,000 | ||||||||||||||
cost of products sold | 1,041,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
other incomes | -147,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
net (income) loss attributable to noncontrolling interest in akcea therapeutics, inc. | -6,441,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
net income attributable to ionis pharmaceuticals, inc. common stockholders | 84,443,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
licensing and royalty revenue | 2,331,250 | 265,000 | 448,000 | 8,611,000 | 973,000 | 202,000 | 477,000 | 1,439,000 | 858,000 | 474,000 | 200,000 | 1,417,000 | 721,000 | 524,000 | 518,000 | 1,133,000 | 983,000 | 839,000 | 2,360,000 | 1,370,000 | 10,546,000 | 809,000 | 224,000 | 1,891,000 | 547,000 | 975,000 | 6,147,000 | 668,000 | 26,710,000 | 331,000 | 448,000 | 8,114,000 | 784,000 | 53,000 | 490,000 | 336,000 | 1,541,626,000 | 307,000 | 38,000 | 1,626,000 | 5,305,000 | |||||||||||||||
research, development and patent expenses | 240,802,000 | 61,086,000 | 59,264,000 | 53,448,000 | 57,430,000 | 45,660,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||
general and administrative | 3,328,250 | 4,470,000 | 4,462,000 | 4,380,000 | 4,677,000 | 3,430,000 | 3,389,000 | 3,423,000 | 3,234,000 | 3,096,000 | 3,209,000 | 2,976,000 | 3,800,000 | 3,105,000 | 2,874,000 | 3,010,000 | 2,945,000 | 2,855,000 | 3,051,000 | 2,819,000 | 3,830,000 | 3,335,000 | 3,673,000 | 3,677,000 | 2,710,000 | 2,566,000 | 1,724,000 | 19,102,568,000 | 2,137,000 | 2,373,000 | 2,568,000 | 2,453,000 | ||||||||||||||||||||||||
equity in net income of regulus therapeutics inc. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss on early retirement of debt | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
research and development | 42,631,000 | 38,312,000 | 42,758,000 | 36,551,000 | 40,435,000 | 38,714,000 | 47,219,000 | 39,924,000 | 36,009,000 | 34,245,000 | 39,333,000 | 34,716,000 | 39,124,000 | 31,987,000 | 40,103,000 | 33,832,000 | 32,146,000 | 28,541,000 | 16,828,000 | 31,968,000 | 31,195,000 | 26,449,000 | 24,296,000 | 20,384,000 | 19,949,000 | 24,240,000 | 18,973,000 | 18,982,000 | 18,372,000 | 18,212,000 | 2,095,032,036,000 | 22,361,000 | 29,566,000 | 32,036,000 | 28,947,000 | |||||||||||||||||||||
basic and diluted net income | -200 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
income from continuing operations, before income tax expense | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
net income from continuing operations | -0.21 | -0.07 | -0.03 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
discontinued operations: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income from discontinued operations | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
gain on sale of ibis biosciences, inc., net of tax | 13,884,000 | 171,773,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
net income from discontinued operations, net of tax | 13,884,000 | 171,744,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
net income attributable to noncontrolling interest in regulus therapeutics inc. | 1,487,000 | 1,136,000 | 857,000 | 913,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
net income attributable to isis pharmaceuticals, inc. common stockholders | -13,986,000 | -12,454,000 | -25,154,000 | -9,658,000 | -6,958,000 | -6,924,000 | -2,896,000 | 171,843,000 | ||||||||||||||||||||||||||||||||||||||||||||||||
basic and diluted net income per share: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
net income from continuing operations attributable to isis pharmaceuticals, inc. common stockholders | -0.14 | -0.13 | -0.25 | -0.1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
net income from discontinued operations | 0.14 | 1.76 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
basic and diluted net income attributable to isis pharmaceuticals, inc. common stockholders | -0.14 | -0.13 | -0.25 | -0.1 | -0.07 | -0.07 | ||||||||||||||||||||||||||||||||||||||||||||||||||
income from continuing operations, before income tax benefit | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
net income from continuing operations, net of income tax benefit | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
basic net income per share: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
basic net income attributable to isis pharmaceuticals, inc. common stockholders | -0.03 | 1.76 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
diluted net income per share: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
diluted net income attributable to isis pharmaceuticals, inc. common stockholders | -0.03 | 1.57 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss attributed to noncontrolling interest in symphony genisis, inc. | 8,748,000 | 7,603,000 | 6,806,000 | 5,085,250 | 6,733,000 | 13,608,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||
loss attributed to noncontrolling interest in regulus therapeutics llc | 764,000 | 1,208,000 | 965,000 | 883,000 | 87,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||
loss attributed to noncontrolling interest in ibis biosciences, inc. | 290,750 | 267,000 | 791,000 | 105,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
excess purchase price over carrying value of noncontrolling interest in symphony genisis, inc. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
net income applicable to common stock | -8,658,000 | 3,188,000 | -2,208,000 | -4,285,000 | -105,304,000 | -11,024,000 | -13,020,000 | -14,146,000 | -12,105,000 | -2,172,000 | -17,480,000 | -15,172,000 | -29,658,000 | -32,708,000 | -26,129,000 | -26,487,000 | ||||||||||||||||||||||||||||||||||||||||
restructuring activities | 36,000 | 650,000 | 7,084,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
net income before noncontrolling interest in symphony genisis, inc. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
operating expenses: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
compensation expense/(benefit) related to variable accounting of stock options | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
compensation benefit related to variable accounting of stock options | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
compensation benefit related to stock options | 15,000 | 5,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
accretion of dividends on preferred stock | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
compensation expense related to stock options | 3,238,000 |
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