Quarterly
Annual
| Unit: USD | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2020-06-30 | 2020-03-31 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | 2017-12-31 | 2017-09-30 | 2017-06-30 | 2017-03-31 | 2016-12-31 | 2016-09-30 | 2016-06-30 | 2016-03-31 | 2015-12-31 | 2015-09-30 | 2015-06-30 | 2015-03-31 | 2014-09-30 | 2014-06-30 | 2014-03-31 | 2013-09-30 | 2013-06-30 | 2013-03-31 | 2012-09-30 | 2012-06-30 | 2012-03-31 | 2011-09-30 | 2011-06-30 | 2011-03-31 | 2010-09-30 | 2010-06-30 | 2010-03-31 | 2009-09-30 | 2009-06-30 | 2009-03-31 | 2008-09-30 | 2008-06-30 | 2008-03-31 | 2007-09-30 | 2007-06-30 | 2007-03-31 | 2006-12-31 | 2006-09-30 | 2006-06-30 | 2006-03-31 | 2005-12-31 | 2005-09-30 | 2005-06-30 | 2005-03-31 | 2004-12-31 | 2004-09-30 | 2004-06-30 | 2004-03-31 | 2003-09-30 | 2003-06-30 | 2003-03-31 | 2002-09-30 | 2002-06-30 | 2002-03-31 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
revenues: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
product revenues | 1,149,856,000 | 1,059,414,000 | 922,274,000 | 1,019,407,000 | 962,992,000 | 906,566,000 | 729,923,000 | 861,729,000 | 783,197,000 | 827,005,000 | 693,237,000 | 764,215,000 | 713,010,000 | 663,851,000 | 605,821,000 | 648,038,000 | 594,013,000 | 575,150,000 | 504,811,000 | 559,467,000 | 522,252,000 | 500,290,000 | 486,727,000 | 490,778,000 | 453,998,000 | 433,897,000 | 396,249,000 | 399,156,000 | 367,715,000 | 365,524,000 | 334,505,000 | 321,809,000 | 322,029,000 | 291,667,000 | 264,807,000 | 250,398,000 | 236,623,000 | 212,116,000 | 183,267,000 | 182,021,000 | 161,259,000 | 142,406,000 | 115,330,000 | 97,837,000 | 84,025,000 | 69,651,000 | 60,201,000 | 54,099,000 | 48,289,000 | 43,695,000 | 29,727,000 | 19,279,000 | |||||||||||||||||||||||||||||||||
product royalty revenues | 171,124,000 | 151,115,000 | 130,624,000 | 159,291,000 | 156,879,000 | 137,193,000 | 125,966,000 | 149,612,000 | 130,828,000 | 127,605,000 | 115,436,000 | 132,485,000 | 110,293,000 | 117,546,000 | 122,414,000 | 164,815,000 | 183,974,000 | 120,559,000 | 99,907,000 | 120,042,000 | 98,391,000 | 92,753,000 | 81,780,000 | 88,611,000 | 80,083,000 | 76,035,000 | 61,608,000 | 69,188,000 | 61,923,000 | 55,953,000 | 47,716,000 | 52,314,000 | 44,487,000 | 34,769,000 | 29,221,000 | 33,225,000 | 29,626,000 | 25,958,000 | 21,903,000 | 23,646,000 | 18,138,000 | 17,364,000 | 15,673,000 | 12,093,000 | 12,340,000 | 9,826,000 | 8,184,000 | 5,800,000 | 5,909,000 | ||||||||||||||||||||||||||||||||||||
milestone and contract revenues | 45,000,000 | 5,000,000 | 18,000,000 | 25,000,000 | 2,000,000 | 5,000,000 | 30,000,000 | 130,000,000 | 5,000,000 | 50,000,000 | 35,000,000 | 10,000,000 | 110,000,000 | 95,000,000 | 17,500,000 | 20,000,000 | 40,000,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
total revenues | 1,365,980,000 | 1,215,529,000 | 1,052,898,000 | 1,178,698,000 | 1,137,871,000 | 1,043,759,000 | 880,889,000 | 1,013,341,000 | 919,025,000 | 954,610,000 | 808,673,000 | 926,700,000 | 823,303,000 | 911,397,000 | 733,235,000 | 862,853,000 | 812,987,000 | 705,709,000 | 604,718,000 | 789,509,000 | 620,643,000 | 688,043,000 | 568,507,000 | 579,389,000 | 551,581,000 | 529,932,000 | 497,857,000 | 528,402,000 | 449,683,000 | 521,516,000 | 382,282,000 | 444,156,000 | 381,534,000 | 326,444,000 | 384,082,000 | 326,498,000 | 269,469,000 | 246,288,000 | 263,464,000 | 243,881,000 | 187,611,000 | 162,984,000 | 159,275,000 | 198,147,000 | 99,582,000 | 89,792,000 | 85,123,000 | 101,675,000 | 71,077,000 | 60,492,000 | 86,542,000 | 36,179,000 | 16,782,000 | 16,811,000 | 31,973,000 | 16,872,000 | 49,847,000 | 17,288,000 | 939,000 | 789,000 | 671,000 | 1,061,000 | 614,000 | 1,307,000 | 6,690,000 | 10,576,000 | 7,422,000 | 7,056,000 | 7,268,000 | 6,855,000 | 6,465,000 | ||||||||||||||
yoy | 20.05% | 16.46% | 19.53% | 16.32% | 23.81% | 9.34% | 8.93% | 9.35% | 11.63% | 4.74% | 10.29% | 7.40% | 1.27% | 29.15% | 21.25% | 9.29% | 30.99% | 2.57% | 6.37% | 36.27% | 12.52% | 29.84% | 14.19% | 9.65% | 22.66% | 1.61% | 30.23% | 18.97% | 17.86% | 59.76% | -0.47% | 36.04% | 41.59% | 32.55% | 45.78% | 33.88% | 43.63% | 51.11% | 65.41% | 23.08% | 88.40% | 81.51% | 87.11% | 94.88% | 40.10% | 48.44% | -1.64% | 181.03% | 323.53% | 259.84% | 170.67% | 114.43% | -66.33% | -2.76% | 3305.01% | 2038.40% | 7328.76% | 1529.41% | 52.93% | -39.63% | -89.97% | -89.97% | -91.73% | -81.48% | -7.95% | 54.28% | 14.80% | ||||||||||||||||||
qoq | 12.38% | 15.45% | -10.67% | 3.59% | 9.02% | 18.49% | -13.07% | 10.26% | -3.73% | 18.05% | -12.74% | 12.56% | -9.67% | 24.30% | -15.02% | 6.13% | 15.20% | 16.70% | -23.41% | 27.21% | -9.80% | 21.03% | -1.88% | 5.04% | 4.09% | 6.44% | -5.78% | 17.51% | -13.77% | 36.42% | -13.93% | 16.41% | 16.88% | -15.01% | 17.64% | 21.16% | 9.41% | -6.52% | 8.03% | 29.99% | 15.11% | 2.33% | -19.62% | 98.98% | 10.90% | 5.49% | -16.28% | 43.05% | 17.50% | -30.10% | 139.21% | 115.58% | -0.17% | -47.42% | 89.50% | -66.15% | 188.33% | 1741.11% | 19.01% | 17.59% | -36.76% | 72.80% | -53.02% | -80.46% | -36.74% | 42.50% | 5.19% | -2.92% | 6.02% | 6.03% | |||||||||||||||
costs, expenses and other: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cost of product revenues | 99,001,000 | 78,766,000 | 73,188,000 | 88,485,000 | 85,993,000 | 76,634,000 | 60,956,000 | 69,751,000 | 60,091,000 | 68,326,000 | 56,822,000 | 59,163,000 | 54,584,000 | 50,636,000 | 42,614,000 | 43,874,000 | 39,869,000 | 38,028,000 | 29,220,000 | 36,323,000 | 34,322,000 | 33,364,000 | 27,319,000 | 32,215,000 | 30,040,000 | 29,406,000 | 22,588,000 | 26,366,000 | 24,795,000 | 24,856,000 | 18,106,000 | 22,359,000 | 22,036,000 | 20,260,000 | 14,824,000 | 19,610,000 | 20,205,000 | 12,367,000 | 6,005,000 | 9,704,000 | 8,040,000 | 6,254,000 | 2,974,000 | 221,000 | 187,000 | 168,000 | 155,000 | 157,000 | 150,000 | 31,000 | 16,000 | 11,000 | |||||||||||||||||||||||||||||||||
contract dispute settlement | -242,251,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
research and development | 506,584,000 | 494,917,000 | 437,279,000 | 466,034,000 | 573,174,000 | 1,138,380,000 | 429,260,000 | 444,494,000 | 375,709,000 | 400,750,000 | 406,641,000 | 501,360,000 | 384,007,000 | 347,196,000 | 353,373,000 | 472,827,000 | 334,945,000 | 343,511,000 | 306,896,000 | 405,945,000 | 438,109,000 | 286,601,000 | 1,085,287,000 | 312,867,000 | 281,336,000 | 289,363,000 | 270,545,000 | 304,238,000 | 292,527,000 | 298,089,000 | 303,103,000 | 446,938,000 | 269,612,000 | 201,839,000 | 407,972,000 | 161,585,000 | 143,184,000 | 120,269,000 | 156,824,000 | 116,632,000 | 132,073,000 | 112,445,000 | 118,365,000 | 88,537,000 | 84,683,000 | 75,585,000 | 71,704,000 | 60,950,000 | 52,763,000 | 50,079,000 | 51,588,000 | 48,960,000 | 44,604,000 | 46,047,000 | 36,282,000 | 30,609,000 | 28,883,000 | 31,439,000 | 26,535,000 | 29,035,000 | 29,587,000 | 36,949,000 | 38,132,000 | 32,955,000 | 25,044,000 | 23,301,000 | 23,906,000 | 23,559,000 | 19,558,000 | 19,724,000 | 24,757,000 | 23,942,000 | 27,356,000 | 26,556,000 | 17,764,000 | 17,892,000 | 18,629,000 | 25,565,000 | 26,184,000 | 28,619,000 | 29,870,000 | 30,186,000 | 47,406,000 | 37,717,000 | 33,743,000 |
selling, general and administrative | 329,081,000 | 331,022,000 | 325,691,000 | 326,710,000 | 309,209,000 | 305,982,000 | 300,256,000 | 293,865,000 | 267,893,000 | 283,929,000 | 315,606,000 | 272,819,000 | 266,460,000 | 253,277,000 | 209,584,000 | 226,202,000 | 190,704,000 | 168,859,000 | 153,795,000 | 166,988,000 | 120,788,000 | 117,998,000 | 111,148,000 | 136,177,000 | 102,608,000 | 105,943,000 | 123,983,000 | 108,358,000 | 96,522,000 | 108,029,000 | 121,498,000 | 97,829,000 | 91,271,000 | 90,072,000 | 87,234,000 | 96,085,000 | 75,776,000 | 66,792,000 | 64,596,000 | 52,467,000 | 47,599,000 | 51,679,000 | 44,871,000 | 39,446,000 | 40,899,000 | 36,974,000 | 26,447,000 | 23,249,000 | 22,261,000 | 20,520,000 | 19,719,000 | 21,396,000 | 14,282,000 | 11,858,000 | 10,825,000 | 8,458,000 | 7,485,000 | 5,794,000 | 4,841,000 | 4,086,000 | 4,821,000 | 4,005,000 | 4,103,000 | 4,354,000 | 3,587,000 | 3,535,000 | 3,692,000 | 3,277,000 | 3,454,000 | 3,421,000 | 3,876,000 | 3,412,000 | 2,710,000 | 2,734,000 | 2,801,000 | 3,510,000 | 5,236,000 | 6,004,000 | 6,292,000 | 8,585,000 | 7,694,000 | 7,377,000 | 12,147,000 | 12,748,000 | 14,168,000 |
(gain) loss on change in fair value of acquisition-related contingent consideration | -12,204,000 | -456,000 | 3,536,000 | -426,000 | -3,049,500 | -21,893,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
(profit) and loss sharing under collaboration agreements | -1,025,000 | -549,000 | -1,362,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
total costs, expenses and other | 922,462,000 | 685,215,000 | 847,730,000 | 877,185,000 | 991,786,000 | 1,521,889,000 | 788,991,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income from operations | 443,518,000 | 530,314,000 | 205,168,000 | 301,513,000 | 146,085,000 | -478,130,000 | 91,898,000 | 187,270,000 | 214,705,000 | 193,780,000 | 24,770,000 | 70,093,000 | 138,376,000 | 254,431,000 | 116,540,000 | 110,734,000 | 235,410,000 | 140,836,000 | 98,797,000 | 164,229,000 | 5,326,000 | 230,773,000 | -664,004,000 | 95,008,000 | 134,316,000 | 98,612,000 | 74,070,000 | 81,975,000 | 31,119,000 | 83,239,000 | -67,110,000 | -132,588,000 | 14,958,000 | 7,200,000 | -133,304,000 | 42,079,000 | 22,292,000 | 44,589,000 | 36,039,000 | 65,078,000 | -101,000 | 69,943,000 | 17,319,000 | 15,219,000 | 13,624,000 | -17,993,000 | -34,093,000 | -20,340,000 | -60,943,000 | -33,477,000 | -30,170,000 | -26,818,000 | -54,273,000 | -37,464,000 | -22,777,000 | -18,897,000 | |||||||||||||||||||||||||||||
yoy | 203.60% | -210.91% | 123.26% | 61.00% | -31.96% | -346.74% | 271.01% | 167.17% | 55.16% | -23.84% | -78.75% | -36.70% | -41.22% | 80.66% | 17.96% | -32.57% | 4320.02% | -38.97% | -114.88% | 72.86% | -96.03% | 134.02% | -996.45% | 15.90% | 331.62% | 18.47% | -210.37% | -161.83% | 108.04% | 1056.10% | -49.66% | -415.09% | -32.90% | -83.85% | -469.89% | -35.34% | -22171.29% | -6.96% | 303.85% | -46.25% | 13.00% | -24.16% | 12.29% | -10.64% | 32.46% | 41.92% | |||||||||||||||||||||||||||||||||||||||
qoq | -16.37% | 158.48% | -31.95% | 106.40% | -130.55% | -620.28% | -50.93% | -12.78% | 10.80% | 682.32% | -64.66% | -49.35% | -45.61% | 118.32% | 5.24% | -52.96% | 67.15% | 42.55% | -39.84% | 2983.53% | -97.69% | -134.75% | -798.89% | -29.27% | 36.21% | 33.13% | -9.64% | 163.42% | -62.61% | -224.03% | -49.38% | -986.40% | 107.75% | -105.40% | -416.79% | 88.76% | -50.01% | 23.72% | -44.62% | -64533.66% | -47.22% | 67.62% | -66.62% | 82.04% | 10.96% | 12.50% | -50.59% | 44.87% | 64.48% | 20.53% | |||||||||||||||||||||||||||||||||||
operating margin % | 32.47% | 43.63% | 19.49% | 25.58% | 12.84% | -45.81% | 10.43% | 18.48% | 23.36% | 20.30% | 3.06% | 7.56% | 16.81% | 27.92% | 15.89% | 12.83% | 28.96% | 19.96% | 16.34% | 20.80% | 0.86% | 33.54% | -116.80% | 16.40% | 24.35% | 18.61% | 14.88% | 15.51% | 6.92% | 15.96% | -17.56% | -29.85% | 3.92% | 2.21% | -34.71% | 12.89% | 8.27% | 18.10% | 13.68% | 26.68% | -0.05% | 35.30% | 17.03% | 17.59% | 27.33% | 0% | |||||||||||||||||||||||||||||||||||||||
interest income | 26,781,000 | 25,136,000 | 22,929,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
interest expense | -592,000 | -594,000 | -660,000 | -419,000 | -774,000 | -657,000 | -430,000 | -804,000 | -623,000 | -655,000 | -469,000 | -667,000 | -641,000 | -678,000 | -680,000 | -752,000 | -439,000 | -358,000 | -359,000 | -428,000 | -544,000 | -600,000 | -602,000 | -607,000 | -597,000 | -316,000 | -335,000 | -355,000 | -405,000 | -398,000 | -385,000 | -373,000 | -204,000 | -384,000 | -5,939,000 | -9,470,000 | -9,479,000 | -9,662,000 | -10,134,000 | -10,213,000 | -11,209,000 | -4,317,000 | -4,230,000 | -4,623,000 | -4,868,000 | -3,520,000 | -2,299,000 | -2,439,000 | -2,439,000 | -2,450,000 | -2,389,000 | -2,538,000 | |||||||||||||||||||||||||||||||||
gain on equity investments | 8,558,000 | -4,151,000 | -1,343,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
other | 4,043,000 | 7,307,000 | 8,096,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income before benefit from income taxes | 482,308,000 | 558,012,000 | 234,190,000 | 313,724,000 | 156,524,000 | -389,777,000 | 236,159,000 | 140,814,750 | 233,799,000 | 277,604,000 | 51,856,000 | 112,125,250 | 148,588,000 | 229,378,000 | 70,535,000 | 112,606,000 | 209,469,000 | 171,633,000 | 69,322,000 | 168,102,000 | -3,508,000 | 307,264,000 | -704,076,000 | 126,004,000 | 148,019,000 | 108,671,000 | 104,097,000 | 9,445,000 | 38,302,000 | 35,210,000 | 24,447,000 | 55,688,000 | -39,573,000 | 9,430,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||
benefit from income taxes | 58,139,000 | 153,013,000 | 75,987,000 | 112,512,000 | 50,068,000 | 54,824,000 | 66,611,000 | 41,684,750 | 62,530,000 | 74,056,000 | 30,153,000 | 34,075,500 | 35,813,000 | 67,946,000 | 32,543,000 | 16,423,500 | 27,730,000 | 22,177,000 | 15,787,000 | 18,252,000 | 11,695,000 | 16,966,000 | 16,566,000 | 14,999,000 | 19,748,000 | 3,353,000 | 1,785,000 | 652,500 | 1,425,000 | 785,000 | 400,000 | 128,250 | 9,000 | 136,000 | 367,000 | 72,000 | 70,000 | 49,000 | 49,000 | 71,000 | 43,000 | 26,000 | 67,000 | 331,000 | 327,000 | 226,000 | 99,000 | 128,000 | 190,000 | 241,000 | 260,000 | 300,000 | 300,000 | 303,000 | |||||||||||||||||||||||||||||||
net income | 424,169,000 | 404,999,000 | 158,203,000 | 201,212,000 | 106,456,000 | -444,601,000 | 169,548,000 | 201,079,000 | 171,269,000 | 203,548,000 | 21,703,000 | 28,461,000 | 112,775,000 | 161,432,000 | 37,992,000 | 563,851,000 | 181,739,000 | 149,456,000 | 53,535,000 | 149,850,000 | -15,203,000 | 290,298,000 | -720,642,000 | 111,005,000 | 128,271,000 | 105,318,000 | 102,312,000 | 69,063,000 | 29,176,000 | 52,394,000 | -41,140,000 | -149,629,000 | 36,054,000 | -12,484,000 | -187,083,000 | 8,873,000 | 36,877,000 | 34,425,000 | 24,047,000 | 55,176,000 | -39,582,000 | 9,294,000 | -18,359,000 | 59,293,000 | -36,873,000 | -33,957,000 | -22,037,000 | -2,571,000 | -21,710,000 | 4,037,000 | -53,078,000 | -51,870,000 | -31,701,000 | 3,044,000 | -24,494,000 | -20,131,000 | -37,526,000 | -25,976,000 | -63,600,000 | -37,715,000 | -43,012,000 | -26,900,000 | -55,784,000 | -38,411,000 | -17,541,000 | -13,441,000 | |||||||||||||||||||
yoy | 298.45% | -191.09% | -6.69% | 0.07% | -37.84% | -318.43% | 681.22% | 606.51% | 51.87% | 26.09% | -42.87% | -94.95% | -37.95% | 8.01% | -29.03% | 276.28% | -1295.42% | -48.52% | -107.43% | 34.99% | -111.85% | 175.64% | -804.36% | 60.73% | 339.65% | 101.01% | -348.69% | -146.16% | -19.08% | -519.69% | -78.01% | -1786.34% | -2.23% | -136.26% | -877.99% | -83.92% | -193.17% | 270.40% | -230.98% | -6.94% | 7.35% | -127.37% | -16.69% | -2406.22% | 56.41% | -645.88% | -58.15% | -1843.69% | -46.62% | -12.75% | -3.43% | 14.01% | -1.81% | 145.21% | 100.13% | ||||||||||||||||||||||||||||||
qoq | 4.73% | 156.00% | -21.37% | 89.01% | -123.94% | -362.23% | -15.68% | 17.41% | -15.86% | 837.88% | -23.74% | -74.76% | -30.14% | 324.91% | -93.26% | 210.25% | 21.60% | 179.17% | -64.27% | -1085.66% | -105.24% | -140.28% | -749.20% | -13.46% | 21.79% | 2.94% | 48.14% | 136.71% | -44.31% | -227.36% | -72.51% | -515.01% | -388.80% | -93.33% | -2208.45% | -75.94% | 7.12% | 43.16% | -56.42% | -239.40% | -525.89% | -150.62% | -130.96% | -260.80% | 8.59% | 54.09% | 757.14% | -637.78% | 2.33% | -1141.43% | -46.35% | 44.46% | -59.16% | 68.63% | -12.32% | 59.90% | -51.78% | 45.23% | 118.98% | 30.50% | |||||||||||||||||||||||||
net income margin % | 31.05% | 33.32% | 15.03% | 17.07% | 9.36% | -42.60% | 19.25% | 19.84% | 18.64% | 21.32% | 2.68% | 3.07% | 13.70% | 17.71% | 5.18% | 65.35% | 22.35% | 21.18% | 8.85% | 18.98% | -2.45% | 42.19% | -126.76% | 19.16% | 23.26% | 19.87% | 20.55% | 13.07% | 6.49% | 10.05% | -10.76% | -33.69% | 9.45% | -3.82% | -48.71% | 2.72% | 13.69% | 13.98% | 9.13% | 22.62% | -21.10% | 5.70% | -11.53% | 29.92% | -37.03% | -37.82% | -25.89% | -2.53% | -35.89% | 4.66% | -316.28% | -308.55% | -187.89% | 6.11% | -366.13% | 0% | |||||||||||||||||||||||||||||
net income per share | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
basic | 2.17 | 2.09 | 0.82 | 0.96 | 0.55 | -2.04 | 0.76 | 0.9 | 0.76 | 0.91 | 0.1 | 0.12 | 0.51 | 0.73 | 0.17 | 2.55 | 0.82 | 0.68 | 0.24 | 0.69 | -0.07 | 1.33 | -3.33 | 0.51 | 0.6 | 0.49 | 0.48 | 0.33 | 0.14 | 0.25 | -0.72 | 0.17 | -0.06 | -0.96 | 0.04 | 0.2 | 0.18 | 0.13 | 0.31 | -0.22 | 0.05 | 0.35 | -0.02 | 0.03 | -0.41 | 0.03 | |||||||||||||||||||||||||||||||||||||||
diluted | 2.11 | 2.04 | 0.8 | 0.95 | 0.54 | -2.04 | 0.75 | 0.89 | 0.76 | 0.9 | 0.1 | 0.12 | 0.5 | 0.72 | 0.17 | 2.54 | 0.82 | 0.67 | 0.24 | 0.69 | -0.07 | 1.32 | -3.33 | 0.5 | 0.59 | 0.48 | 0.47 | 0.32 | 0.14 | 0.24 | -0.72 | 0.17 | -0.06 | -0.96 | 0.05 | 0.19 | 0.18 | 0.12 | 0.3 | -0.22 | 0.05 | 0.33 | -0.02 | 0.03 | 0.02 | ||||||||||||||||||||||||||||||||||||||||
shares used in computing net income per share: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
basic | 195,670 | 193,995 | 193,712 | -4,653 | 192,629 | 218,175 | 224,484 | 200 | 224,078 | 223,248 | 222,960 | 203 | 222,415 | 221,660 | 221,326 | 185 | 220,845 | 220,083 | 219,801 | 389 | 218,784 | 217,549 | 216,721 | 285 | 215,199 | 214,620 | 214,065 | 211 | 212,627 | 212,210 | 2,181 | 206,796 | 205,141 | 195,260 | 241 | 188,029 | 187,682 | 187,184 | 2,223 | 181,387 | 178,676 | 168,592 | 142,284 | 129,224 | 125,330 | 121,630 | |||||||||||||||||||||||||||||||||||||||
diluted | 201,429 | 198,744 | 198,197 | -1,233 | 195,838 | 218,175 | 227,219 | 172 | 226,167 | 225,649 | 225,589 | 332 | 224,175 | 223,661 | 222,950 | -39 | 222,248 | 222,250 | 221,867 | 389 | 218,784 | 220,434 | 216,721 | 264 | 217,791 | 217,483 | 217,061 | 119 | 215,964 | 215,103 | 2,181 | 212,610 | 205,141 | 195,260 | 371 | 194,265 | 193,015 | 192,625 | 9,924 | 181,387 | 186,493 | 189,046 | 142,284 | 137,969 | 125,330 | 128,291 | |||||||||||||||||||||||||||||||||||||||
loss on change in fair value of acquisition-related contingent consideration | 22,761,000 | 893,000 | 8,374,000 | 6,196,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
gain on change in fair value of acquisition-related contingent consideration | 11,572,000 | 5,961,750 | 23,410,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss and (profit) sharing under collaboration agreements | -256,250 | -214,500 | 1,053,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
interest income and other | 29,677,000 | 24,195,000 | 49,769,000 | 44,744,000 | 50,436,000 | 46,371,000 | 42,668,000 | 32,873,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
realized and unrealized gain on equity investments | -10,181,000 | -12,982,000 | 39,241,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
unrealized gain on long term investments | 99,947,000 | 34,054,000 | -26,654,000 | 41,811,000 | -24,897,000 | 4,322,000 | -27,450,000 | 26,765,000 | -509,000 | -13,207,000 | 72,274,000 | -48,132,000 | 15,755,000 | 2,339,000 | -4,625,000 | 20,989,000 | -5,477,750 | -9,949,000 | 22,679,000 | -585,750 | 23,045,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
costs and expenses: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
total costs and expenses | 826,071,000 | 704,320,000 | 760,830,000 | 783,903,000 | 856,607,000 | 684,927,000 | 656,966,000 | 616,695,000 | 752,119,000 | 577,577,000 | 564,873,000 | 505,921,000 | 625,280,000 | 615,317,000 | 457,270,000 | 1,232,511,000 | 484,381,000 | 417,265,000 | 431,320,000 | 423,787,000 | 446,427,000 | 418,564,000 | 438,277,000 | 449,392,000 | 576,744,000 | 366,576,000 | 319,244,000 | 517,386,000 | 284,419,000 | 247,177,000 | 201,699,000 | 227,425,000 | 178,803,000 | 187,712,000 | 170,378,000 | 166,210,000 | 128,204,000 | 125,769,000 | 112,727,000 | 98,306,000 | 84,356,000 | 75,174,000 | 70,630,000 | 71,323,000 | 70,367,000 | 58,886,000 | 57,925,000 | 47,798,000 | 38,928,000 | 36,223,000 | 37,118,000 | 32,502,000 | 33,527,000 | 34,917,000 | 40,854,000 | 41,317,000 | 37,432,000 | 28,065,000 | 26,763,000 | 27,705,000 | 26,615,000 | 23,025,000 | 26,035,000 | 28,834,000 | 27,622,000 | 30,365,000 | 29,736,000 | 20,908,000 | 33,041,000 | 23,733,000 | 66,106,000 | 40,118,000 | 43,419,000 | 37,854,000 | 66,782,000 | 47,911,000 | |||||||||
unrealized loss on long term investments | -5,318,000 | -18,035,500 | -660,000 | -46,585,000 | -27,709,000 | -34,641,000 | -19,574,000 | -5,814,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
collaboration loss sharing | 2,263,750 | 1,769,000 | 2,544,000 | 4,742,000 | 7,543,000 | 9,149,000 | 9,843,000 | 10,484,000 | 12,429,000 | 14,989,000 | 13,253,000 | 2,130,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
other income | 26,637,000 | 11,513,000 | 522,000 | 1,260,000 | 5,716,000 | 1,948,000 | 4,390,000 | -1,407,000 | 4,810,000 | 4,917,000 | 4,817,000 | 8,662,000 | 15,848,000 | 11,961,000 | 15,000,000 | 9,373,000 | 11,279,000 | 10,211,000 | 5,808,000 | 4,462,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
change in fair value of acquisition-related contingent consideration | 3,313,000 | 6,382,000 | 1,673,000 | 2,910,000 | 4,632,000 | 5,526,000 | 3,595,000 | 7,109,000 | 6,054,000 | 6,627,000 | 3,122,000 | 3,281,000 | 6,608,000 | 6,671,000 | 7,465,000 | 4,720,000 | 7,303,000 | 6,685,000 | 9,618,000 | -16,343,000 | 7,073,000 | 7,356,000 | 7,139,000 | 8,012,000 | 2,271,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
other revenues | 58,000 | 45,000 | 39,000 | 61,000 | 33,000 | 18,000 | 8,000 | 54,000 | 6,000 | 6,000 | 80,000 | 58,000 | 3,000 | 3,000 | 101,000 | 1,000 | 39,000 | 142,000 | 60,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
milestone revenues | 30,000,000 | 20,000,000 | 100,000,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
expense related to senior note conversions | -751,000 | -54,130,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income before benefit for income taxes | 11,157,500 | 30,976,000 | 54,008,000 | -40,354,000 | -148,277,000 | 43,354,000 | -9,384,000 | -197,983,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
benefit for income taxes | 1,050,000 | 1,800,000 | 1,614,000 | 786,000 | 1,352,000 | 7,300,000 | 3,100,000 | -10,900,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
basic and diluted net income per share | -0.19 | -0.11 | -0.41 | -0.47 | -0.22 | -0.26 | -0.37 | -0.81 | -0.57 | -0.26 | -0.2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
shares used in computing basic and diluted net income per share | 211,681 | 172,070 | 165,357 | 134,345 | 130,851 | 127,203 | 126,260 | 123,467 | 122,189 | 119,727 | 98,030 | 97,643 | 97,340 | 92,385 | 84,871 | 84,602 | 84,213 | 84,136 | 83,985 | 44 | 83,852 | 83,786 | 83,627 | 20,803.25 | 83,414 | 83,303 | 83,049 | 1,589 | 73,323 | 72,929 | 72,643 | 72,185 | 71,895 | 68,986 | 67,740 | 67,440 | 66,864 | ||||||||||||||||||||||||||||||||||||||||||||||||
contract revenues | 26,250,000 | 15,000,000 | 90,000,000 | 42,869,000 | 3,214,000 | 8,214,000 | 58,214,000 | 38,214,000 | 8,214,000 | 3,214,000 | 28,214,000 | 88,214,000 | 3,214,000 | 10,214,000 | 16,737,000 | 41,737,000 | 16,737,000 | 16,737,000 | 56,737,000 | 16,737,000 | 16,737,000 | 16,737,000 | 31,738,000 | 16,737,000 | 49,737,000 | 16,737,000 | 15,000 | 57,000 | 587,000 | 5,909,000 | 8,933,000 | 6,074,000 | 6,157,000 | 6,249,000 | 6,292,000 | 5,529,000 | |||||||||||||||||||||||||||||||||||||||||||||||||
interest and other income | 6,616,000 | 5,555,000 | 4,125,000 | 1,204,000 | 594,000 | 1,188,000 | 1,137,000 | 1,492,000 | 1,289,000 | 3,026,000 | 1,144,000 | 1,630,000 | 885,000 | 790,000 | 735,000 | 385,000 | 245,000 | 199,000 | 27,000 | 315,000 | 45,000 | 132,000 | 72,000 | 212,000 | 142,000 | 195,000 | 105,000 | 548,000 | 1,253,000 | 1,353,000 | 2,141,000 | 2,883,000 | 3,713,000 | 4,066,000 | 5,209,000 | 3,996,000 | 2,596,000 | 8,886,000 | 2,299,000 | 2,656,000 | 5,420,000 | 2,152,000 | 2,160,000 | -571,000 | 2,387,000 | -413,000 | -11,259,000 | 2,490,000 | 1,233,000 | 1,648,000 | 6,601,000 | ||||||||||||||||||||||||||||||||||
unrealized gain on long term investment | -23,758,000 | 24,301,000 | -854,000 | 27,174,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
unrealized loss on long term investment | -2,950,000 | -466,000 | -31,289,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
debt exchange expense on senior note conversions | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income before income taxes | 59,365,000 | -36,803,000 | -21,988,000 | -2,500,000 | -21,684,000 | 4,104,000 | 3,375,000 | -31,766,000 | -25,976,000 | -63,501,000 | -37,587,000 | -42,822,000 | -26,659,000 | -55,524,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
net income per basic and diluted share: | -220 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
shares used in computing basic and diluted net income per share: | 167,914 | 155,067 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
basic and diluted net income per share: | -0.21 | -0.14 | -0.12 | -0.17 | -0.36 | -0.42 | -0.21 | -0.3 | -0.44 | -0.41 | -0.48 | -0.54 | -0.29 | -0.435 | -0.35 | -0.87 | -0.52 | -0.6 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
debt exchange expense | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
shares used in computing basic and diluted net income per share | 211,681 | 172,070 | 165,357 | 134,345 | 130,851 | 127,203 | 126,260 | 123,467 | 122,189 | 119,727 | 98,030 | 97,643 | 97,340 | 92,385 | 84,871 | 84,602 | 84,213 | 84,136 | 83,985 | 44 | 83,852 | 83,786 | 83,627 | 20,803.25 | 83,414 | 83,303 | 83,049 | 1,589 | 73,323 | 72,929 | 72,643 | 72,185 | 71,895 | 68,986 | 67,740 | 67,440 | 66,864 | ||||||||||||||||||||||||||||||||||||||||||||||||
basic | 195,670 | 193,995 | 193,712 | -4,653 | 192,629 | 218,175 | 224,484 | 200 | 224,078 | 223,248 | 222,960 | 203 | 222,415 | 221,660 | 221,326 | 185 | 220,845 | 220,083 | 219,801 | 389 | 218,784 | 217,549 | 216,721 | 285 | 215,199 | 214,620 | 214,065 | 211 | 212,627 | 212,210 | 2,181 | 206,796 | 205,141 | 195,260 | 241 | 188,029 | 187,682 | 187,184 | 2,223 | 181,387 | 178,676 | 168,592 | 142,284 | 129,224 | 125,330 | 121,630 | |||||||||||||||||||||||||||||||||||||||
diluted | 201,429 | 198,744 | 198,197 | -1,233 | 195,838 | 218,175 | 227,219 | 172 | 226,167 | 225,649 | 225,589 | 332 | 224,175 | 223,661 | 222,950 | -39 | 222,248 | 222,250 | 221,867 | 389 | 218,784 | 220,434 | 216,721 | 264 | 217,791 | 217,483 | 217,061 | 119 | 215,964 | 215,103 | 2,181 | 212,610 | 205,141 | 195,260 | 371 | 194,265 | 193,015 | 192,625 | 9,924 | 181,387 | 186,493 | 189,046 | 142,284 | 137,969 | 125,330 | 128,291 | |||||||||||||||||||||||||||||||||||||||
other incomes | 20,000 | 691,000 | 1,126,000 | 406,000 | 509,000 | 123,000 | 107,000 | -221,000 | 13,000 | 2,890,000 | 201,000 | 268,000 | 299,000 | 446,000 | 343,000 | 11,639,000 | -132,000 | 34,537,000 | 7,642,000 | -35,000 | 290,000 | 1,103,000 | 292,000 | 1,371,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
license and royalty revenues | 78,000 | 163,000 | 45,000 | 74,000 | 235,000 | 135,000 | 110,000 | 551,000 | 939,000 | 789,000 | 671,000 | 1,046,000 | 557,000 | 720,000 | 781,000 | 1,643,000 | 1,348,000 | 899,000 | 1,019,000 | 563,000 | 936,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
interest and other income | 52,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss on debt redemption | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
basic and diluted loss per share: | -0.26 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss on debt repurchases | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
gain on repurchase of convertible subordinated notes | 85,000 | -226,000 | 706,000 | 1,937,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss on certain derivative financial instruments | -126,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income from continuing operations before income taxes | -20,284,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income from continuing operations | -13,415,750 | -15,838,000 | -20,520,000 | -18,911,500 | -30,207,000 | -25,154,000 | -20,284,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income from discontinued operation, net of tax | 39,750 | 9,000 | 153,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
continuing operations | -0.25 | -0.19 | -0.24 | -0.21 | -0.33 | -0.36 | -0.3 | -0.24 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
discontinued operations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
gain/(loss) on certain derivative financial instruments | 39,000 | -77,000 | -177,000 | -45,000 | 140,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
revenues | 1,028,000 | 1,228,000 | 2,676,000 | 2,915,000 | -1,052,000 | 3,393,000 | 5,163,000 | 6,641,000 | 13,249,000 | 11,036,000 | 12,509,000 | 22,390,000 | 29,059,000 | 29,014,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
gain on certain derivative financial instruments | 36,000 | 16,000 | -216,000 | 200,000 | 108,000 | 155,000 | -613,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income from discontinued operations, net of tax | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
benefitfor income taxes | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
gain on debt repurchase | 421,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
discontinued operation | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
purchased in-process research and development | 6,250,000 | 28,116,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss on sale of assets | 9,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
operating expenses: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
total operating expenses | 59,854,000 | 51,836,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income before income taxes and accounting change | -38,111,000 | -17,241,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income before accounting change | -38,411,000 | -17,541,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cumulative effect of accounting change | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
per share data: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
interest and other income/(expense) | 8,157,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income before income taxes, extraordinary item and accounting change | -13,138,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income before extraordinary item and accounting change | -13,441,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
extraordinary gain |
The information provided in this report is taken from www.sec.gov and many other data providers. While we have conducted our best efforts to ensure that the parsed data is accurate, we cannot guarantee its accuracy. Please use caution and understand that any consequences of its use are your own responsibility.