7Baggers

Illumina, Inc
(NASDAQ:ILMN) 

ILMN stock logo

Illumina, Inc. provides sequencing and array-based solutions for genetic and genomic analysis. Its products and services serve customers in a range of markets enabling the adoption of genomic solutions in research and clinical settings for applications in the life sciences, oncology, reproductive he...

Founded: 1998
Full Time Employees: 7,700
CEO: Francis deSouza  
Sector: Healthcare
Industry: Diagnostics & Research

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Quarterly
Annual
    Unit: USD2026-03-29 2025-12-28 2025-09-28 2025-06-29 2025-03-30 2024-12-29 2024-09-29 2024-06-30 2024-03-31 2023-12-31 2023-10-01 2023-07-02 2023-04-02 2023-01-01 2022-10-02 2022-07-03 2022-04-03 2022-01-02 2021-10-03 2021-07-04 2021-04-04 2021-01-03 2020-09-27 2020-06-28 2020-03-29 2019-12-29 2019-09-29 2019-06-30 2019-03-31 2018-12-30 2018-09-30 2018-07-01 2018-04-01 2017-12-31 2017-10-01 2017-07-02 2017-04-02 2017-01-01 2016-10-02 2016-07-03 2016-04-03 2016-01-03 2015-09-27 2015-06-28 2015-03-29 2014-12-28 2014-09-28 2014-06-29 2014-03-30 2013-12-29 2013-09-29 2013-06-30 2013-03-31 2012-12-30 2012-09-30 2012-07-01 2012-04-01 
                                                             
      revenue:
                                                             
      product revenue
    917,000,000 990,000,000 927,000,000 912,000,000 880,000,000 938,000,000 914,000,000 927,000,000 876,000,000 923,000,000 941,000,000 1,001,000,000 922,000,000 914,000,000 963,000,000 1,006,000,000 1,070,000,000 1,065,000,000 978,000,000 972,000,000 953,000,000 831,000,000 676,000,000 527,000,000 701,000,000 812,000,000 746,000,000 704,000,000 667,000,000 738,000,000 710,000,000 673,000,000 628,000,000 658,000,000 596,000,000 543,000,000 491,000,000 525,581,000 513,744,000 509,922,000 482,750,000 497,922,000 470,824,000 462,760,000 459,127,000 450,329,000 416,163,000 390,808,000 362,211,000 336,386,000 318,603,000 313,497,000 296,170,000 278,933,000 262,418,000 258,839,000 255,636,000 
      service and other revenue
    174,000,000 169,000,000 157,000,000 147,000,000 161,000,000 166,000,000 166,000,000 185,000,000 200,000,000 199,000,000 178,000,000 175,000,000 165,000,000 169,000,000 152,000,000 156,000,000 153,000,000 134,000,000 130,000,000 154,000,000 140,000,000 122,000,000 118,000,000 106,000,000 158,000,000 140,000,000 161,000,000 134,000,000 179,000,000 129,000,000 143,000,000 157,000,000 154,000,000 119,000,000 118,000,000 119,000,000 107,000,000 93,766,000 93,395,000 90,202,000 89,013,000 93,626,000 79,447,000 76,618,000 79,438,000 62,050,000 64,467,000 56,760,000 58,570,000 50,940,000 38,197,000 32,597,000 34,788,000 30,332,000 23,456,000 21,768,000 17,134,000 
      total revenue
    1,091,000,000 1,159,000,000 1,084,000,000 1,059,000,000 1,041,000,000 1,104,000,000 1,080,000,000 1,112,000,000 1,076,000,000 1,122,000,000 1,119,000,000 1,176,000,000 1,087,000,000 1,083,000,000 1,115,000,000 1,162,000,000 1,223,000,000 1,199,000,000 1,108,000,000 1,126,000,000 1,093,000,000 953,000,000 794,000,000 633,000,000 859,000,000 952,000,000 907,000,000 838,000,000 846,000,000 867,000,000 853,000,000 830,000,000 782,000,000 777,000,000 714,000,000 662,000,000 598,000,000 619,347,000 607,139,000 600,124,000 571,763,000 591,548,000 550,271,000 539,378,000 538,565,000 512,379,000 480,630,000 447,568,000 420,781,000 387,326,000 356,800,000 346,094,000 330,958,000 309,265,000 285,874,000 280,607,000 272,770,000 
      yoy
    4.80% 4.98% 0.37% -4.77% -3.25% -1.60% -3.49% -5.44% -1.01% 3.60% 0.36% 1.20% -11.12% -9.67% 0.63% 3.20% 11.89% 25.81% 39.55% 77.88% 27.24% 0.11% -12.46% -24.46% 1.54% 9.80% 6.33% 0.96% 8.18% 11.58% 19.47% 25.38% 30.77% 25.45% 17.60% 10.31% 4.59% 4.70% 10.33% 11.26% 6.16% 15.45% 14.49% 20.51% 27.99% 32.29% 34.71% 29.32% 27.14% 25.24% 24.81% 23.34% 21.33%     
      qoq
    -5.87% 6.92% 2.36% 1.73% -5.71% 2.22% -2.88% 3.35% -4.10% 0.27% -4.85% 8.19% 0.37% -2.87% -4.04% -4.99% 2.00% 8.21% -1.60% 3.02% 14.69% 20.03% 25.43% -26.31% -9.77% 4.96% 8.23% -0.95% -2.42% 1.64% 2.77% 6.14% 0.64% 8.82% 7.85% 10.70% -3.45% 2.01% 1.17% 4.96% -3.34% 7.50% 2.02% 0.15% 5.11% 6.61% 7.39% 6.37% 8.64% 8.56% 3.09% 4.57% 7.01% 8.18% 1.88% 2.87%  
      cost of revenue:
                                                             
      cost of product revenue
    273,000,000 312,000,000 267,000,000 276,000,000 253,000,000 278,000,000 235,000,000 250,000,000 255,000,000 293,000,000 293,000,000 305,000,000 285,000,000 278,000,000 280,000,000 286,000,000 299,000,000 278,000,000 264,000,000 254,000,000 265,000,000 253,000,000 209,000,000 152,000,000 174,000,000 229,000,000 195,000,000 196,000,000 182,000,000 198,000,000 184,000,000 181,000,000 174,000,000 171,000,000 173,000,000 168,000,000 166,000,000 151,343,000 132,423,000 125,107,000 125,326,000 130,775,000 120,954,000 119,459,000 119,624,000 93,069,000 113,103,000 114,307,000 111,441,000 99,795,000 119,954,000 98,150,000 89,978,000 86,348,000 75,873,000 74,911,000 80,151,000 
      cost of service and other revenue
    80,000,000 72,000,000 68,000,000 71,000,000 88,000,000 81,000,000 84,000,000 95,000,000 106,000,000 107,000,000 95,000,000 91,000,000 99,000,000 85,000,000 72,000,000 69,000,000 69,000,000 64,000,000 56,000,000 63,000,000 58,000,000 63,000,000 52,000,000 46,000,000 59,000,000 55,000,000 55,000,000 59,000,000 71,000,000 70,000,000 62,000,000 65,000,000 62,000,000 55,000,000 50,000,000 50,000,000 53,000,000 37,606,000 37,606,000 40,663,000 38,887,000 39,561,000 29,590,000 32,170,000 32,529,000 23,757,000 23,909,000 23,176,000 21,513,000 19,079,000 17,643,000 15,951,000 15,138,000 14,791,000 10,540,000 9,656,000 8,565,000 
      amortization of acquired intangible assets
    17,000,000 16,000,000 16,000,000 17,000,000 17,000,000 17,000,000 16,000,000 46,000,000 48,000,000 48,000,000 47,000,000 48,000,000 48,000,000 48,000,000 46,000,000 40,000,000 40,000,000 40,000,000 18,000,000 7,000,000 6,000,000 7,000,000 7,000,000 7,000,000 7,000,000 6,000,000 9,000,000 10,000,000 9,000,000 9,000,000 10,000,000 9,000,000 8,000,000 9,000,000 9,000,000 10,000,000 11,000,000 10,959,000 10,960,000 10,549,000 10,496,000 10,853,000 12,188,000 11,384,000 11,385,000 10,616,000 9,677,000 9,545,000 9,535,000 9,206,000 9,263,000 8,584,000 6,550,000 4,479,000 3,588,000 3,043,000 3,043,000 
      total cost of revenue
    370,000,000 400,000,000 351,000,000 364,000,000 358,000,000 376,000,000 335,000,000 391,000,000 409,000,000 448,000,000 435,000,000 444,000,000 432,000,000 411,000,000 398,000,000 395,000,000 408,000,000 382,000,000 338,000,000 324,000,000 329,000,000 323,000,000 268,000,000 205,000,000 240,000,000 290,000,000 259,000,000 265,000,000 262,000,000 277,000,000 256,000,000 255,000,000 244,000,000 235,000,000 232,000,000 228,000,000 230,000,000 199,908,000 180,989,000 176,319,000 174,709,000 181,189,000 162,732,000 163,013,000 163,538,000 127,442,000 146,689,000 147,028,000 142,489,000 128,080,000 146,860,000 122,685,000 111,666,000 105,618,000 90,001,000 87,610,000 91,759,000 
      gross profit
    721,000,000 759,000,000 733,000,000 695,000,000 683,000,000 728,000,000 745,000,000 721,000,000 667,000,000 674,000,000 684,000,000 732,000,000 655,000,000 672,000,000 717,000,000 767,000,000 815,000,000 817,000,000 770,000,000 802,000,000 764,000,000 630,000,000 526,000,000 428,000,000 619,000,000 662,000,000 648,000,000 573,000,000 584,000,000 590,000,000 597,000,000 575,000,000 538,000,000 542,000,000 482,000,000 434,000,000 368,000,000 419,439,000 426,150,000 423,805,000 397,054,000 410,359,000 387,539,000 376,365,000 375,027,000 384,937,000 333,941,000 300,540,000 278,292,000 259,246,000 209,940,000 223,409,000 219,292,000 203,647,000 195,873,000 192,997,000 181,011,000 
      yoy
    5.56% 4.26% -1.61% -3.61% 2.40% 8.01% 8.92% -1.50% 1.83% 0.30% -4.60% -4.56% -19.63% -17.75% -6.88% -4.36% 6.68% 29.68% 46.39% 87.38% 23.42% -4.83% -18.83% -25.31% 5.99% 12.20% 8.54% -0.35% 8.55% 8.86% 23.86% 32.49% 46.20% 29.22% 13.11% 2.41% -7.32% 2.21% 9.96% 12.60% 5.87% 6.60% 16.05% 25.23% 34.76% 48.48% 59.06% 34.52% 26.90% 27.30% 7.18% 15.76% 21.15%     
      qoq
    -5.01% 3.55% 5.47% 1.76% -6.18% -2.28% 3.33% 8.10% -1.04% -1.46% -6.56% 11.76% -2.53% -6.28% -6.52% -5.89% -0.24% 6.10% -3.99% 4.97% 21.27% 19.77% 22.90% -30.86% -6.50% 2.16% 13.09% -1.88% -1.02% -1.17% 3.83% 6.88% -0.74% 12.45% 11.06% 17.93% -12.26% -1.57% 0.55% 6.74% -3.24% 5.89% 2.97% 0.36% -2.57% 15.27% 11.11% 7.99% 7.35% 23.49% -6.03% 1.88% 7.68% 3.97% 1.49% 6.62%  
      gross margin %
    66.09% 65.49% 67.62% 65.63% 65.61% 65.94% 68.98% 64.84% 61.99% 60.07% 61.13% 62.24% 60.26% 62.05% 64.30% 66.01% 66.64% 68.14% 69.49% 71.23% 69.90% 66.11% 66.25% 67.61% 72.06% 69.54% 71.44% 68.38% 69.03% 68.05% 69.99% 69.28% 68.80% 69.76% 67.51% 65.56% 61.54% 67.72% 70.19% 70.62% 69.44% 69.37% 70.43% 69.78% 69.63% 75.13% 69.48% 67.15% 66.14% 66.93% 58.84% 64.55% 66.26% 65.85% 68.52% 68.78% 66.36% 
      operating expense:
                                                             
      research and development
    240,000,000 239,000,000 229,000,000 247,000,000 252,000,000 256,000,000 253,000,000 325,000,000 339,000,000 341,000,000 315,000,000 358,000,000 341,000,000 346,000,000 325,000,000 327,000,000 323,000,000 350,000,000 436,000,000 202,000,000 197,000,000 199,000,000 172,000,000 155,000,000 156,000,000 161,000,000 151,000,000 166,000,000 169,000,000 176,000,000 159,000,000 151,000,000 137,000,000 137,000,000 134,000,000 130,000,000 145,000,000 129,915,000 125,917,000 124,589,000 123,994,000 114,347,000 99,226,000 96,182,000 91,772,000 142,947,000 85,082,000 82,985,000 77,041,000 76,728,000 70,957,000 67,608,000 61,450,000 56,907,000 54,056,000 71,223,000 48,839,000 
      selling, general and administrative
    272,000,000 309,000,000 277,000,000 234,000,000 267,000,000 279,000,000 239,000,000 147,000,000 439,000,000 485,000,000 303,000,000 450,000,000 378,000,000 432,000,000 146,000,000 410,000,000 308,000,000 426,000,000 879,000,000 413,000,000 374,000,000 298,000,000 192,000,000 177,000,000 274,000,000 233,000,000 189,000,000 202,000,000 211,000,000 217,000,000 197,000,000 197,000,000 183,000,000 175,000,000 167,000,000 169,000,000 163,000,000 146,091,000 139,146,000 148,535,000 149,233,000 147,251,000 136,648,000 124,441,000 116,317,000 122,173,000 119,888,000 114,649,000 109,573,000 111,649,000 95,617,000 88,700,000 85,074,000 79,715,000 69,791,000 68,516,000 67,969,000 
      total operating expense
    512,000,000 558,000,000 506,000,000 481,000,000 519,000,000 553,000,000 4,000,000 2,358,000,000 778,000,000 838,000,000 1,438,000,000 820,000,000 719,000,000 799,000,000 4,374,000,000 1,346,000,000 631,000,000 776,000,000 1,315,000,000 615,000,000 571,000,000 497,000,000 364,000,000 332,000,000 430,000,000 394,000,000 340,000,000 368,000,000 380,000,000 393,000,000 356,000,000 348,000,000 320,000,000 312,000,000 301,000,000 291,000,000 316,000,000 276,423,000 265,448,000 261,936,000 275,609,000 266,359,000 246,757,000 224,432,000 198,901,000 182,054,000 214,448,000 200,301,000 186,196,000 185,462,000 164,476,000 163,403,000 264,439,000 144,301,000 147,059,000 150,017,000 131,399,000 
      income from operations
    209,000,000 201,000,000 227,000,000 214,000,000 164,000,000 175,000,000 741,000,000 -1,637,000,000 -111,000,000 -164,000,000 -754,000,000 -88,000,000 -64,000,000 -127,000,000 -3,657,000,000 -579,000,000 184,000,000 41,000,000 -545,000,000 187,000,000 193,000,000 133,000,000 162,000,000 96,000,000 189,000,000 268,000,000 308,000,000 205,000,000 204,000,000 197,000,000 241,000,000 227,000,000 218,000,000 230,000,000 181,000,000 143,000,000 52,000,000 143,016,000 160,702,000 161,869,000 121,445,000 144,000,000 140,782,000 151,933,000 176,126,000 202,883,000 119,493,000 100,239,000 92,096,000 73,784,000 45,464,000 60,006,000 -45,147,000 59,346,000 48,814,000 42,980,000 49,612,000 
      yoy
    27.44% 14.86% -69.37% -113.07% -247.75% -206.71% -198.28% 1760.23% 73.44% 29.13% -79.38% -84.80% -134.78% -409.76% 571.01% -409.63% -4.66% -69.17% -436.42% 94.79% 2.12% -50.37% -47.40% -53.17% -7.35% 36.04% 27.80% -9.69% -6.42% -14.35% 33.15% 58.74% 319.23% 60.82% 12.63% -11.66% -57.18% -0.68% 14.15% 6.54% -31.05% -29.02% 17.82% 51.57% 91.24% 174.97% 162.83% 67.05% -303.99% 24.33% -6.86% 39.61% -191.00%     
      qoq
    3.98% -11.45% 6.07% 30.49% -6.29% -76.38% -145.27% 1374.77% -32.32% -78.25% 756.82% 37.50% -49.61% -96.53% 531.61% -414.67% 348.78% -107.52% -391.44% -3.11% 45.11% -17.90% 68.75% -49.21% -29.48% -12.99% 50.24% 0.49% 3.55% -18.26% 6.17% 4.13% -5.22% 27.07% 26.57% 175.00% -63.64% -11.01% -0.72% 33.29% -15.66% 2.29% -7.34% -13.74% -13.19% 69.79% 19.21% 8.84% 24.82% 62.29% -24.23% -232.91% -176.07% 21.58% 13.57% -13.37%  
      operating margin %
    19.16% 17.34% 20.94% 20.21% 15.75% 15.85% 68.61% -147.21% -10.32% -14.62% -67.38% -7.48% -5.89% -11.73% -327.98% -49.83% 15.04% 3.42% -49.19% 16.61% 17.66% 13.96% 20.40% 15.17% 22.00% 28.15% 33.96% 24.46% 24.11% 22.72% 28.25% 27.35% 27.88% 29.60% 25.35% 21.60% 8.70% 23.09% 26.47% 26.97% 21.24% 24.34% 25.58% 28.17% 32.70% 39.60% 24.86% 22.40% 21.89% 19.05% 12.74% 17.34% -13.64% 19.19% 17.08% 15.32% 18.19% 
      other income:
                                                             
      interest income
    11,000,000 10,000,000 9,000,000 10,000,000 11,000,000 10,000,000 11,000,000 13,000,000 12,000,000 11,000,000 13,000,000 17,000,000 17,000,000 7,000,000 3,000,000 1,000,000     1,000,000 15,000,000 5,000,000 7,000,000 14,000,000 16,000,000 16,000,000 20,000,000 23,000,000 13,000,000 14,000,000 11,000,000 5,000,000 6,000,000 4,000,000 5,000,000 4,000,000 3,116,000 2,056,000 3,403,000 1,224,000 -780,000 2,767,000 1,344,000 1,693,000 947,000 534,000 1,464,000 956,000 965,000 1,267,000 722,000 1,933,000 8,838,000 3,459,000 1,385,000 2,526,000 
      interest expense
    -24,000,000 -26,000,000 -25,000,000 -25,000,000 -25,000,000 -25,000,000 -36,000,000 -20,000,000 -18,000,000 -18,000,000 -19,000,000 -19,000,000 -20,000,000 -9,000,000 -6,000,000 -6,000,000 -6,000,000 -13,000,000 -14,000,000 -16,000,000 -19,000,000 -16,000,000 -11,000,000 -11,000,000 -11,000,000 -11,000,000 -11,000,000 -15,000,000 -15,000,000 -20,000,000 -15,000,000 -11,000,000 -11,000,000 -11,000,000 -10,000,000 -8,000,000 -8,000,000 -8,301,000 -8,208,000 -8,147,000 -8,525,000 -6,931,000 -12,821,000 -11,205,000 -11,164,000 -11,076,000 -10,987,000 -9,922,000 -9,743,000 -9,944,000 -9,954,000 -10,045,000 -9,747,000 -9,586,000 -9,483,000 -9,508,000 -9,202,000 
      other income
    -39,000,000 192,000,000 9,000,000 107,000,000 32,000,000 -79,750,000 4,000,000 -332,000,000 8,000,000   1,000,000  -39,000,000 -12,000,000 -53,000,000  58,000,000 979,000,000 36,000,000  167,000,000 59,000,000 73,000,000 -14,000,000 -4,000,000 -43,000,000 136,000,000 21,000,000 19,000,000 -8,000,000 5,000,000 9,000,000 -2,000,000  1,000,000 455,000,000 -3,588,000 -186,000 -150,000 1,452,000    -1,191,000 -7,965,000 -1,024,000  479,000 -416,750 370,000   -606,000 855,000 -70,000 -2,663,000 
      total other income
    -52,000,000 176,000,000 -7,000,000 92,000,000 18,000,000    2,000,000     -41,000,000 -15,000,000 -58,000,000  45,000,000 965,000,000 20,000,000  166,000,000 53,000,000 69,000,000 -11,000,000 1,000,000 -38,000,000 141,000,000 29,000,000 12,000,000 -9,000,000 5,000,000 3,000,000 -7,000,000 -6,000,000 -2,000,000 451,000,000 -8,773,000 -6,338,000  -5,849,000    1,920,000         44,557,000 -5,169,000 -8,193,000 -9,339,000 
      income before income taxes
    157,000,000 377,000,000 220,000,000 306,000,000 182,000,000 187,000,000 720,000,000 -1,976,000,000 -109,000,000 -167,000,000 -782,000,000 -89,000,000 -78,000,000 -168,000,000 -3,672,000,000 -637,000,000 140,000,000 86,000,000 420,000,000 207,000,000 169,000,000 299,000,000 215,000,000 165,000,000 178,000,000 269,000,000 270,000,000 346,000,000 233,000,000 209,000,000 232,000,000 232,000,000 221,000,000 223,000,000 175,000,000 141,000,000 503,000,000 134,243,000 154,364,000 156,975,000 115,596,000 135,007,000 128,917,000 141,172,000 178,046,000 192,061,000 112,443,000 60,466,000 83,788,000 120,369,000 37,147,000 49,360,000 -47,562,000 103,903,000 43,645,000 34,787,000 40,273,000 
      provision for income taxes
    23,000,000 43,000,000 70,000,000 71,000,000 51,000,000  15,000,000 12,000,000 17,000,000 8,000,000 -28,000,000 145,000,000 -81,000,000 -29,000,000 144,000,000 -102,000,000 54,000,000 -26,000,000 103,000,000 22,000,000 22,000,000 42,000,000 36,000,000 118,000,000 5,000,000 30,000,000 36,000,000 53,000,000 9,000,000 12,000,000 44,000,000 32,000,000 24,000,000 166,000,000 23,000,000 21,000,000    40,581,000 28,377,000 32,143,000 13,296,000 38,925,000 41,388,000 38,781,000 18,954,000 13,861,000 23,811,000         
      net income
    134,000,000 334,000,000 150,000,000 235,000,000 131,000,000 187,000,000 705,000,000 -1,988,000,000 -126,000,000 -175,000,000 -754,000,000 -234,000,000 3,000,000 -139,000,000 -3,816,000,000 -535,000,000 86,000,000 162,500,000 317,000,000 185,000,000 147,000,000                       102,247,000 136,658,000 153,280,000 93,489,000 46,605,000 59,977,000 80,661,000 31,357,000 35,877,000 -22,587,000 71,903,000 29,748,000 23,401,000 26,202,000 
      yoy
    2.29% 78.61% -78.72% -111.82% -203.97% -206.86% -193.50% 749.57% -4300.00% 25.90% -80.24% -56.26% -96.51% -185.54% -1303.79% -389.19% -41.50%                           119.39% 127.85% 90.03% 198.14% 29.90% -365.54% 12.18% 5.41% 53.31% -186.20%     
      qoq
    -59.88% 122.67% -36.17% 79.39% -29.95% -73.48% -135.46% 1477.78% -28.00% -76.79% 222.22% -7900.00% -102.16% -96.36% 613.27% -722.09% -47.08% -48.74% 71.35% 25.85%                        -25.18% -10.84% 63.96% 100.60% -22.30% -25.64% 157.23% -12.60% -258.84% -131.41% 141.71% 27.12% -10.69%  
      net income margin %
    12.28% 28.82% 13.84% 22.19% 12.58% 16.94% 65.28% -178.78% -11.71% -15.60% -67.38% -19.90% 0.28% -12.83% -342.24% -46.04% 7.03% 13.55% 28.61% 16.43% 13.45% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 18.96% 25.37% 29.92% 19.45% 10.41% 14.25% 20.83% 8.79% 10.37% -6.82% 23.25% 10.41% 8.34% 9.61% 
      earnings per share:
                                                             
      basic
    0.88 2.17 0.98 1.49 0.83 -2.215 4.43  -0.79    0.02 -0.87 -24.26 -3.4 0.55 0.68 2.09 1.27 1.01 1.76 1.22 0.32 1.18 1.62 1.59 2.01 1.58 1.43 1.35 1.42 1.42 0.47 1.12 0.87 2.5 0.8 0.88 0.83 0.61 0.72 0.81               
      diluted
    0.87 2.16 0.98 1.49 0.82 -2.215 4.42  -0.79    0.02 -0.87 -24.26 -3.4 0.55 0.68 2.08 1.26 1.75 1.21 0.32 1.17 1.61 1.58 1.99 1.57 1.41 1.33 1.41 1.41 0.47 1.11 0.87 2.48 0.8 0.87 0.82 0.6 0.71 0.79               
      shares used in computing earnings per share:
                                                             
      basic
    153 -1 153 157 159  159 159 159  158 158 158  157 157 157 152 146 146  146 147 147  147 147 147  147 147 147  146 146 146 146,705 146,778 146,866 379 145,349               
      diluted
    154 -1 154 157 159  160 159 159  158 158 158  157 157 159 153 147 147  148 148 148  148 149 149 149 148 148  148 147 147 -9 147,901 147,889 148,357 -39 149,672               
      goodwill and intangible impairment
           1,886,000,000  6,000,000 821,000,000                                               
      legal contingency and settlement
         18,000,000 -488,000,000   6,000,000 -1,000,000 12,000,000  21,000,000 -11,000,000                                           
      total other expense
         12,000,000 -21,000,000 -339,000,000  -11,250,000 -28,000,000 -1,000,000 -14,000,000    -44,000,000    -24,000,000                   -4,894,000  -5,176,500 -11,865,000 -10,761,000  -13,782,750 -7,050,000 -39,773,000 -8,308,000 -5,344,500 -8,317,000 -10,646,000 -2,415,000     
      loss per share:
                                                             
      basic
           -12.48  -1.558 -4.77 -1.48                                              
      diluted
           -12.48  -1.558 -4.77 -1.48                                              
      shares used in computing loss per share:
                                                             
      basic
    153 -1 153 157 159  159 159 159  158 158 158  157 157 157 152 146 146  146 147 147  147 147 147  147 147 147  146 146 146 146,705 146,778 146,866 379 145,349               
      diluted
    154 -1 154 157 159  160 159 159  158 158 158  157 157 159 153 147 147  148 148 148  148 149 149 149 148 148  148 147 147 -9 147,901 147,889 148,357 -39 149,672               
      other expense
             -8,250,000 -22,000,000  -11,000,000    -38,000,000    -6,000,000                     -1,401,000 -4,711,000 -900,000    -31,315,000    -1,323,000 -714,000     
      goodwill impairment
                  3,914,000,000                                           
      legal contingencies
                   609,000,000                    -8,000,000 8,000,000   -11,490,000 2,000,000 4,000,000 15,000,000   -82,043,000 7,705,000     9,516,000 105,853,000     
      consolidated net income
                         257,000,000 179,000,000 47,000,000 173,000,000 239,000,000 234,000,000 293,000,000 224,000,000 197,000,000 188,000,000 200,000,000 197,000,000 57,000,000 152,000,000 120,000,000 348,000,000 107,542,000 116,935,000 116,394,000 87,219,000 102,864,000 115,621,000               
      add: net loss attributable to noncontrolling interests
                               3,000,000 9,000,000 13,000,000 11,000,000 9,000,000 11,000,000 11,000,000 11,000,000 8,000,000    4,018,000 2,368,000 1,613,000 2,556,000               
      net income attributable to illumina stockholders
                         257,000,000 179,000,000 47,000,000 173,000,000 239,000,000 234,000,000 296,000,000 233,000,000 210,000,000 199,000,000 209,000,000 208,000,000 68,000,000 163,000,000 128,000,000 367,000,000 123,762,000 128,888,000 120,412,000 89,587,000 104,477,000 118,177,000               
      earnings per share attributable to illumina stockholders:
                                                             
      basic
    0.88 2.17 0.98 1.49 0.83 -2.215 4.43  -0.79    0.02 -0.87 -24.26 -3.4 0.55 0.68 2.09 1.27 1.01 1.76 1.22 0.32 1.18 1.62 1.59 2.01 1.58 1.43 1.35 1.42 1.42 0.47 1.12 0.87 2.5 0.8 0.88 0.83 0.61 0.72 0.81               
      diluted
    0.87 2.16 0.98 1.49 0.82 -2.215 4.42  -0.79    0.02 -0.87 -24.26 -3.4 0.55 0.68 2.08 1.26 1.75 1.21 0.32 1.17 1.61 1.58 1.99 1.57 1.41 1.33 1.41 1.41 0.47 1.11 0.87 2.48 0.8 0.87 0.82 0.6 0.71 0.79               
      net income attributable to illumina stockholders for earnings per share
                                 210 199 209 208 68 163 128 366 118,509 128,682 121,971                  
      shares used in computing earnings per common share:
                                                             
      basic
    153 -1 153 157 159  159 159 159  158 158 158  157 157 157 152 146 146  146 147 147  147 147 147  147 147 147  146 146 146 146,705 146,778 146,866 379 145,349               
      diluted
    154 -1 154 157 159  160 159 159  158 158 158  157 157 159 153 147 147  148 148 148  148 149 149 149 148 148  148 147 147 -9 147,901 147,889 148,357 -39 149,672               
      benefit from income taxes
                                        155,000,000 26,701,000 37,429,000               9,838,500 13,897,000 11,386,000 14,071,000 
      add: net income attributable to noncontrolling interests
                                        19,000,000 16,220,000 11,953,000                   
      headquarter relocation
                                         417,000 385,000 302,000 382,000 436,000 -5,226,000 1,480,000 699,000 1,281,000 870,000 2,892,000 595,000 2,856,000 518,000 -1,507,000      
      acquisition related expense (gain)
                                             -1,612,250 1,109,000 2,329,000  -83,750 903,000           
      cost-method investment gain
                                             119,000 2,900,000  12,582,000             
      acquisition related gain
                                                -9,887,000   -225,000          
      net income per basic share
                                               710 950 1,110 660 360 470 640 250 290 -180 580 240 190 210 
      net income per diluted share
                                               690 920 1,030 630 310 400 580 220 260 -180 530 220 180 200 
      shares used in calculating basic net income per share
                                               144,220 143,771 2,263 141,142 130,583 128,146 544 125,465 124,362 123,768 70 122,930 123,214 122,642 
      shares used in calculating diluted net income per share
                                               148,969 148,683 -107 147,512 149,121 150,619 1,306 140,601 139,377 123,768 567 132,507 133,011 133,859 
      unsolicited tender offer related expense
                                                      1,326,000 4,811,000 7,484,000 4,394,000 3,956,000 6,694,000 8,092,000 
      cost-method investment related gain
                                                  4,427,000   55,244,000   6,113,000     
      acquisition related (gain) expense
                                                    -1,013,000 -5,771,000 -3,942,000 -5,725,000  615,000 -357,000   
      restructuring
                                                             
      provision for for income taxes
                                                     -1,425,500 5,790,000 13,483,000 -24,975,000     
      acquisition related expense
                                                        3,821,000   1,080,000 1,737,000 
      headquarter relocation expense
                                                        757,000 2,883,000 19,475,000 1,830,000 2,140,000 
      restructuring charges
                                                         88,000 138,000 674,000 2,622,000 
    Balance Sheets:
    Quarterly
    Annual
      Unit: USD2026-03-29 2025-12-28 2025-09-28 2025-06-29 2025-03-30 2024-12-29 2024-09-29 2024-06-30 2024-03-31 2023-12-31 2023-10-01 2023-07-02 2023-04-02 2023-01-01 2022-10-02 2022-07-03 2022-04-03 2022-01-02 2021-10-03 2021-07-04 2021-04-04 2021-01-03 2020-09-27 2020-06-28 2020-03-29 2019-12-29 2019-09-29 2019-06-30 2019-03-31 2018-12-30 2018-09-30 2018-07-01 2018-04-01 2017-12-31 2017-10-01 2017-07-02 2017-04-02 2017-01-01 2016-10-02 2016-07-03 2016-04-03 2016-01-03 2015-09-27 2015-06-28 2015-03-29 2014-12-28 2014-09-28 2014-06-29 2014-03-30 2013-12-29 2013-09-29 2013-06-30 2013-03-31 2012-12-30 2012-09-30 2012-07-01 2012-04-01 
                                                               
        assets
                                                               
        current assets:
                                                               
        cash and cash equivalents
      1,089,000,000 1,418,000,000 1,050,000,000 934,000,000 1,113,000,000 1,127,000,000 869,000,000 920,000,000 1,108,000,000 1,048,000,000 927,000,000 1,553,000,000 1,494,000,000 2,011,000,000 1,000,000,000 1,289,000,000 1,351,000,000 1,232,000,000 1,080,000,000 4,196,000,000 4,433,000,000 1,810,000,000 1,761,000,000 1,770,000,000 1,991,000,000 2,042,000,000 1,815,000,000 1,943,000,000 2,270,000,000 1,144,000,000 1,346,000,000 1,344,000,000 1,560,000,000 1,225,000,000 1,354,000,000 1,219,000,000 981,000,000 734,516,000 794,697,000 951,662,000 754,910,000 768,770,000 551,529,000 591,057,000 533,537,000 636,154,000 829,895,000 675,221,000 518,513,000 711,637,000 691,836,000 783,611,000 443,082,000 433,981,000 343,089,000 316,412,000 260,194,000 
        short-term investments
      66,000,000 215,000,000 228,000,000 221,000,000 124,000,000 93,000,000 70,000,000 74,000,000  6,000,000 6,000,000 6,000,000 24,000,000 26,000,000 41,000,000 38,000,000 65,000,000 107,000,000 185,000,000 90,000,000 197,000,000 1,662,000,000 1,563,000,000 1,498,000,000 1,341,000,000 1,372,000,000 1,351,000,000 1,230,000,000 1,345,000,000 2,368,000,000 2,043,000,000 1,168,000,000 813,000,000 920,000,000 687,000,000 674,000,000 797,000,000 824,208,000 741,569,000 473,594,000 588,182,000 617,450,000 887,877,000 919,325,000 832,952,000 702,217,000 441,532,000 427,835,000 573,289,000 453,966,000 336,155,000 345,852,000 624,388,000 916,223,000 889,977,000 985,274,000 1,006,169,000 
        accounts receivable
      738,000,000 854,000,000 729,000,000 701,000,000 699,000,000 735,000,000 699,000,000 641,000,000 635,000,000 734,000,000 690,000,000 741,000,000 665,000,000 671,000,000 628,000,000 642,000,000 614,000,000 648,000,000 604,000,000 540,000,000 517,000,000 487,000,000 464,000,000 385,000,000 472,000,000 573,000,000 541,000,000 470,000,000 457,000,000 514,000,000 433,000,000 395,000,000 400,000,000 411,000,000 383,000,000 372,000,000 368,000,000 381,316,000 381,632,000 372,480,000 402,514,000 385,529,000 413,474,000 368,611,000 350,044,000 289,458,000 276,675,000 258,694,000 293,045,000 238,946,000 235,437,000 207,413,000 210,831,000 214,975,000 218,145,000 188,562,000 202,234,000 
        inventory
      611,000,000 564,000,000 590,000,000 575,000,000 537,000,000 547,000,000 574,000,000 561,000,000 584,000,000 587,000,000 615,000,000 617,000,000 586,000,000 568,000,000 559,000,000 518,000,000 465,000,000 431,000,000 401,000,000 380,000,000 364,000,000 372,000,000 415,000,000 435,000,000 384,000,000 359,000,000 417,000,000 420,000,000 412,000,000 386,000,000 374,000,000 362,000,000 350,000,000 333,000,000 327,000,000 309,000,000 299,000,000 300,170,000 312,242,000 311,364,000 287,919,000 270,777,000 233,781,000 223,620,000 205,184,000 191,144,000 199,298,000 177,534,000 164,231,000 154,099,000 159,866,000 168,070,000 167,959,000 158,718,000 147,684,000 133,844,000 128,684,000 
        prepaid expenses and other current assets
      234,000,000 238,000,000 199,000,000 210,000,000 200,000,000 244,000,000 161,000,000 263,000,000 256,000,000 234,000,000 268,000,000 306,000,000 403,000,000 285,000,000 259,000,000 404,000,000 260,000,000 295,000,000 181,000,000 104,000,000 131,000,000 152,000,000 126,000,000 106,000,000 136,000,000 105,000,000 98,000,000 93,000,000 61,000,000 78,000,000 66,000,000 68,000,000 71,000,000 91,000,000 54,000,000 69,000,000 72,000,000 77,881,000 47,696,000 33,921,000 40,273,000 54,297,000 80,030,000 83,402,000 89,459,000 29,844,000 57,624,000 36,508,000 42,516,000 22,811,000 28,877,000 56,558,000 30,525,000 32,700,000 20,112,000 16,366,000 17,318,000 
        total current assets
      2,738,000,000 3,289,000,000 2,796,000,000 2,641,000,000 2,673,000,000 2,746,000,000 2,373,000,000 2,459,000,000 2,583,000,000 2,609,000,000 2,506,000,000 3,223,000,000 3,172,000,000 3,561,000,000 2,487,000,000 2,891,000,000 2,755,000,000 2,713,000,000 2,451,000,000 5,310,000,000 5,642,000,000 4,483,000,000 4,329,000,000 4,194,000,000 4,324,000,000 4,451,000,000 4,222,000,000 4,156,000,000 4,545,000,000 4,490,000,000 4,262,000,000 3,337,000,000 3,194,000,000 2,980,000,000 2,805,000,000 2,643,000,000 2,517,000,000 2,318,091,000 2,277,836,000 2,143,021,000 2,073,798,000 2,096,823,000 2,210,428,000 2,237,691,000 2,060,281,000 1,889,603,000 1,906,954,000 1,620,721,000 1,631,943,000 1,617,535,000 1,537,646,000 1,646,391,000 1,550,773,000 1,787,048,000 1,646,236,000 1,664,372,000 1,637,291,000 
        property and equipment
      755,000,000 759,000,000 748,000,000 764,000,000 782,000,000 815,000,000 832,000,000 859,000,000 964,000,000 1,007,000,000 1,040,000,000 1,069,000,000 1,082,000,000 1,091,000,000 1,068,000,000 1,055,000,000 1,034,000,000 1,024,000,000 1,009,000,000 915,000,000 915,000,000 922,000,000 910,000,000 890,000,000 890,000,000 889,000,000 875,000,000 854,000,000 852,000,000 1,075,000,000 1,060,000,000 1,036,000,000 983,000,000 931,000,000 862,000,000 837,000,000 734,000,000 713,334,000 633,856,000 511,354,000 385,253,000 342,694,000 308,722,000 302,840,000 280,628,000 265,264,000 247,643,000 230,113,000 210,372,000 202,666,000 193,649,000 187,362,000 186,792,000 166,167,000 154,869,000 147,917,000 143,494,000 
        operating lease right-of-use assets
      371,000,000 370,000,000 382,000,000 397,000,000 410,000,000 419,000,000 453,000,000 460,000,000 550,000,000 544,000,000 581,000,000 638,000,000 658,000,000 653,000,000 680,000,000 693,000,000 706,000,000 672,000,000 676,000,000 566,000,000 529,000,000 532,000,000 545,000,000 549,000,000 559,000,000 555,000,000 555,000,000 558,000,000 574,000,000                             
        goodwill
      1,284,000,000 1,113,000,000 1,113,000,000 1,113,000,000 1,113,000,000 1,113,000,000 1,113,000,000 1,079,000,000 2,545,000,000 2,545,000,000 2,527,000,000 3,239,000,000 3,239,000,000 3,239,000,000 3,238,000,000 7,158,000,000 7,113,000,000 7,113,000,000 7,098,000,000 966,000,000 897,000,000 897,000,000 897,000,000 894,000,000 824,000,000 824,000,000 824,000,000 824,000,000 831,000,000 831,000,000 831,000,000 831,000,000 775,000,000 771,000,000 771,000,000 771,000,000 771,000,000 775,995,000 775,995,000 775,995,000 776,029,000 752,629,000 756,687,000 724,904,000 724,904,000 724,904,000 724,887,000 721,648,000 723,259,000 723,061,000 667,192,000 596,588,000 604,493,000 369,327,000 370,189,000 321,853,000 321,853,000 
        intangible assets
      430,000,000 210,000,000 225,000,000 238,000,000 278,000,000 295,000,000 305,000,000 278,000,000 2,940,000,000 2,993,000,000 3,029,000,000 3,188,000,000 3,237,000,000 3,285,000,000 3,335,000,000 3,202,000,000 3,209,000,000 3,250,000,000 3,351,000,000 162,000,000 134,000,000 142,000,000 149,000,000 156,000,000 138,000,000 145,000,000 152,000,000 162,000,000 175,000,000 185,000,000 195,000,000 205,000,000 168,000,000 175,000,000 185,000,000 196,000,000 207,000,000 242,652,000 255,560,000 268,469,000 269,576,000 273,621,000 286,346,000 288,177,000 301,302,000 314,500,000 299,345,000 304,850,000 316,984,000 331,173,000 297,911,000 304,469,000 307,214,000 130,196,000 134,829,000 89,007,000 103,007,000 
        deferred tax assets
      458,000,000 454,000,000 490,000,000 534,000,000 553,000,000 567,000,000 617,000,000 632,000,000              20,000,000 19,000,000 13,000,000 91,000,000 64,000,000 88,000,000 69,000,000 87,000,000 70,000,000 86,000,000 108,000,000 100,000,000 88,000,000 117,000,000 103,000,000 83,000,000 123,317,000 182,122,000 186,462,000 196,198,000                 
        other assets
      523,000,000 449,000,000 423,000,000 400,000,000 373,000,000 348,000,000 321,000,000 314,000,000 458,000,000 413,000,000 439,000,000 417,000,000 423,000,000 423,000,000 448,000,000 449,000,000 457,000,000 445,000,000 478,000,000 756,000,000 638,000,000 589,000,000 555,000,000 552,000,000 435,000,000 388,000,000 373,000,000 350,000,000 326,000,000 308,000,000 325,000,000 334,000,000 322,000,000 312,000,000 306,000,000 308,000,000 286,000,000 107,211,000 102,458,000 99,789,000 92,852,000 87,465,000 84,538,000 82,790,000 68,856,000 95,521,000 59,648,000 87,597,000 69,676,000 56,091,000 78,002,000 78,677,000 73,270,000 73,164,000 77,450,000 76,730,000 69,350,000 
        total assets
      6,559,000,000 6,644,000,000 6,177,000,000 6,087,000,000 6,182,000,000 6,303,000,000 6,014,000,000 6,081,000,000 10,040,000,000 10,111,000,000 10,122,000,000 11,774,000,000 11,811,000,000 12,252,000,000 11,256,000,000 15,448,000,000 15,274,000,000 15,217,000,000 15,063,000,000 8,675,000,000 8,755,000,000 7,585,000,000 7,404,000,000 7,248,000,000 7,261,000,000 7,316,000,000 7,089,000,000 6,973,000,000 7,390,000,000 6,959,000,000 6,759,000,000 5,851,000,000 5,542,000,000 5,257,000,000 5,046,000,000 4,858,000,000 4,598,000,000 4,280,600,000 4,227,827,000 3,985,090,000 3,793,706,000 3,687,747,000 3,733,548,000 3,703,125,000 3,499,093,000 3,339,640,000 3,278,206,000 3,035,055,000 3,053,570,000 3,019,006,000 2,817,696,000 2,823,202,000 2,744,188,000 2,566,085,000 2,437,983,000 2,348,738,000 2,301,474,000 
        liabilities and stockholders’ equity
                                                               
        current liabilities:
                                                               
        accounts payable
      218,000,000 240,000,000 218,000,000 200,000,000 207,000,000 221,000,000 191,000,000 199,000,000 201,000,000 245,000,000 240,000,000 244,000,000 242,000,000 293,000,000 281,000,000 282,000,000 291,000,000 332,000,000 248,000,000 200,000,000 178,000,000 192,000,000 156,000,000 135,000,000 130,000,000 149,000,000 143,000,000 139,000,000 137,000,000 184,000,000 156,000,000 149,000,000 151,000,000 160,000,000 158,000,000 175,000,000 142,000,000 137,930,000 134,090,000 250,670,000 154,680,000 139,226,000 123,432,000 107,884,000 106,674,000 82,626,000 96,069,000 91,513,000 86,471,000 73,655,000 63,126,000 67,648,000 76,627,000 65,727,000 74,971,000 56,668,000 59,861,000 
        accrued liabilities
      849,000,000 846,000,000 746,000,000 762,000,000 734,000,000 827,000,000 784,000,000 1,265,000,000 1,273,000,000 1,325,000,000 1,242,000,000 1,309,000,000 1,239,000,000 1,232,000,000 1,142,000,000 1,354,000,000 700,000,000 761,000,000 666,000,000 674,000,000 602,000,000 541,000,000 452,000,000 477,000,000 425,000,000 516,000,000 476,000,000 473,000,000 473,000,000 513,000,000 450,000,000 422,000,000 388,000,000 432,000,000 381,000,000 378,000,000 386,000,000 342,751,000 315,204,000 330,326,000 326,548,000 396,339,000 358,259,000 314,722,000 296,150,000 335,276,000 304,133,000 259,676,000 215,292,000 219,120,000 199,977,000 198,788,000 188,751,000 201,877,000 191,821,000 206,813,000 198,040,000 
        term debt, current portion
      499,000,000 499,000,000 998,000,000 499,000,000 499,000,000 499,000,000  744,000,000                                                  
        total current liabilities
      1,566,000,000 1,585,000,000 1,962,000,000 1,461,000,000 1,440,000,000 1,547,000,000 975,000,000 2,208,000,000 1,474,000,000 1,570,000,000 1,482,000,000 2,303,000,000 2,230,000,000 2,773,000,000 2,669,000,000 2,881,000,000 1,490,000,000 1,093,000,000 914,000,000 874,000,000 1,268,000,000 1,244,000,000 1,115,000,000 1,115,000,000 1,054,000,000 665,000,000 619,000,000 612,000,000 1,241,000,000 1,804,000,000 1,735,000,000 1,217,000,000 1,180,000,000 746,000,000 665,000,000 682,000,000 721,000,000 704,665,000 628,855,000 581,507,000 481,228,000 610,494,000 583,857,000 725,053,000 710,251,000 722,158,000 856,401,000 649,207,000 1,149,779,000 322,063,000 418,925,000 418,880,000 409,941,000 304,571,000 303,099,000 299,141,000 292,926,000 
        operating lease liabilities
      475,000,000 486,000,000 506,000,000 528,000,000 539,000,000 554,000,000 613,000,000 616,000,000 700,000,000 687,000,000 698,000,000 726,000,000 747,000,000 744,000,000 748,000,000 775,000,000 803,000,000 774,000,000 784,000,000 704,000,000 664,000,000 671,000,000 678,000,000 681,000,000 696,000,000 695,000,000 691,000,000 698,000,000 718,000,000                             
        term debt
      1,490,000,000 1,490,000,000 994,000,000 1,492,000,000 1,491,000,000 1,490,000,000 1,988,000,000 1,490,000,000                                                  
        other long-term liabilities
      352,000,000 360,000,000 334,000,000 348,000,000 344,000,000 339,000,000 313,000,000 331,000,000 642,000,000 620,000,000 555,000,000 702,000,000 654,000,000 649,000,000 613,000,000 853,000,000 845,000,000 915,000,000 1,085,000,000 238,000,000 229,000,000 303,000,000 245,000,000 230,000,000 224,000,000 202,000,000 209,000,000 211,000,000 212,000,000 359,000,000 352,000,000 343,000,000 364,000,000 360,000,000 222,000,000 212,000,000 212,000,000 213,955,000 204,273,000 198,568,000 185,526,000 180,505,000 173,061,000 183,331,000 171,739,000 167,904,000 167,656,000 188,870,000 191,398,000 191,221,000 192,807,000 192,167,000 206,195,000 134,369,000 111,690,000 75,341,000 62,333,000 
        stockholders’ equity:
                                                               
        common stock
      2,000,000  2,000,000 2,000,000 2,000,000  2,000,000 2,000,000 2,000,000  2,000,000 2,000,000 2,000,000  2,000,000 2,000,000 2,000,000  2,000,000 2,000,000 2,000,000  2,000,000 2,000,000 2,000,000  2,000,000 2,000,000 2,000,000  2,000,000 2,000,000 2,000,000  2,000,000 2,000,000 2,000,000  1,882,000 1,878,000 1,876,000  1,849,000 1,829,000 1,823,000  1,794,000 1,785,000 1,778,000  1,739,000 1,726,000 1,711,000 1,703,000 1,690,000 1,685,000 1,681,000 
        additional paid-in capital
      7,862,000,000 7,822,000,000 7,762,000,000 7,676,000,000 7,608,000,000 7,525,000,000 7,449,000,000 7,347,000,000 9,658,000,000 9,555,000,000 9,487,000,000 9,397,000,000 9,311,000,000 9,207,000,000 9,129,000,000 9,033,000,000 8,957,000,000 8,938,000,000 8,849,000,000 3,993,000,000 3,914,000,000 3,815,000,000 3,737,000,000 3,649,000,000 3,631,000,000 3,560,000,000 3,510,000,000 3,436,000,000 3,385,000,000 3,290,000,000 3,093,000,000 2,939,000,000 2,897,000,000 2,833,000,000 2,891,000,000 2,836,000,000 2,798,000,000 2,733,394,000 2,738,001,000 2,664,865,000 2,617,681,000 2,497,501,000 2,454,876,000 2,388,181,000 2,311,970,000 2,172,940,000 2,101,183,000 2,056,922,000 2,681,983,000 2,562,705,000 2,484,457,000 2,530,075,000 2,463,555,000 2,419,831,000 2,370,969,000 2,339,049,000 2,309,285,000 
        accumulated other comprehensive income
      1,000,000 -10,000,000 -12,000,000 -21,000,000 8,000,000 22,000,000  14,000,000 12,000,000 -1,000,000 21,000,000 12,000,000 -1,000,000 3,000,000 39,000,000 30,000,000 18,000,000 17,000,000 13,000,000 8,000,000 8,000,000 2,000,000 12,000,000 14,000,000 6,000,000 5,000,000 5,000,000 5,000,000 2,000,000         -1,037,000 1,314,000 2,318,000 1,982,000 36,000 1,040,000 599,000 2,334,000 -1,080,000 361,000 1,333,000 1,208,000 1,234,000 1,368,000 1,163,000 1,703,000 2,123,000 2,447,000 2,203,000 2,263,000 
        accumulated deficit
      -258,000,000 -392,000,000 -726,000,000 -876,000,000 -1,111,000,000 -1,242,000,000 -1,428,000,000 -2,133,000,000 -145,000,000                                               -19,108,000 -42,510,000 
        treasury stock
      -4,931,000,000 -4,699,000,000 -4,645,000,000 -4,523,000,000 -4,139,000,000 -3,934,000,000 -3,893,000,000 -3,794,000,000 -3,793,000,000 -3,792,000,000 -3,769,000,000 -3,767,000,000 -3,764,000,000 -3,755,000,000 -3,720,000,000 -3,718,000,000 -3,714,000,000 -3,702,000,000 -3,643,000,000 -3,878,000,000 -3,872,000,000 -3,848,000,000 -3,517,000,000 -3,389,000,000 -3,244,000,000 -3,021,000,000 -2,906,000,000 -2,705,000,000 -2,702,000,000 -2,616,000,000 -2,462,000,000 -2,356,000,000 -2,354,000,000 -2,341,000,000 -2,226,000,000 -2,148,000,000 -2,145,000,000 -2,022,429,000 -1,862,702,000 -1,846,054,000 -1,742,782,000 -1,673,608,000 -1,439,486,000 -1,396,808,000 -1,390,665,000 -1,272,073,000 -1,236,951,000 -1,294,041,000 -1,379,188,000 -1,240,345,000 -1,240,287,000 -1,240,209,000 -1,215,102,000 -1,187,623,000 -1,163,532,000 -1,143,046,000 -1,110,547,000 
        total stockholders’ equity
      2,676,000,000 2,723,000,000 2,381,000,000 2,258,000,000 2,368,000,000 2,373,000,000 2,125,000,000 1,436,000,000 5,734,000,000 5,745,000,000 5,898,000,000 6,555,000,000 6,693,000,000 6,599,000,000 6,731,000,000 10,444,000,000 10,895,000,000 10,740,000,000 10,593,000,000 5,180,000,000 4,922,000,000 4,694,000,000 4,700,000,000 4,563,000,000 4,635,000,000 4,613,000,000 4,439,000,000 4,332,000,000 4,070,000,000 3,845,000,000 3,594,000,000 3,351,000,000 3,073,000,000 2,749,000,000 2,855,000,000 2,715,000,000 2,551,000,000 2,270,235,000 2,319,677,000 2,139,912,000 2,070,923,000 1,848,553,000 1,936,567,000 1,793,912,000 1,623,326,000 1,462,798,000 1,274,313,000 1,080,436,000 1,573,613,000 1,533,202,000 1,374,464,000 1,388,592,000 1,311,827,000 1,318,581,000 1,222,214,000 1,180,783,000 1,160,172,000 
        total liabilities and stockholders’ equity
      6,559,000,000 6,644,000,000 6,177,000,000 6,087,000,000 6,182,000,000 6,303,000,000 6,014,000,000 6,081,000,000 10,040,000,000 10,111,000,000 10,122,000,000 11,774,000,000 11,811,000,000 12,252,000,000 11,256,000,000 15,448,000,000 15,274,000,000 15,217,000,000 15,063,000,000 8,675,000,000 8,755,000,000 7,585,000,000 7,404,000,000 7,248,000,000 7,261,000,000 7,316,000,000 7,089,000,000 6,973,000,000 7,390,000,000 6,959,000,000 6,759,000,000 5,851,000,000 5,542,000,000 5,257,000,000 5,046,000,000 4,858,000,000 4,598,000,000 4,280,600,000 4,227,827,000 3,985,090,000 3,793,706,000 3,687,747,000 3,733,548,000 3,703,125,000 3,499,093,000 3,339,640,000 3,278,206,000 3,035,055,000 3,053,570,000 3,019,006,000 2,817,696,000 2,823,202,000 2,744,188,000 2,566,085,000 2,437,983,000 2,348,738,000 2,301,474,000 
        commitments and contingencies
                                                               
        preferred stock, 0.01 par value...
                                                               
        common stock, 0.01 par value...
       2,000,000    2,000,000    2,000,000    2,000,000    2,000,000    2,000,000    2,000,000    2,000,000    2,000,000    1,887,000    1,859,000    1,805,000    1,753,000        
        accumulated other comprehensive loss
            -5,000,000                       -1,000,000 -2,000,000 -1,000,000 -1,000,000 -1,000,000   -1,000,000                     
        term notes
              1,490,000,000 1,489,000,000 1,489,000,000 1,488,000,000 1,487,000,000 1,487,000,000 495,000,000 495,000,000 495,000,000 993,000,000 993,000,000 992,000,000 992,000,000                                     
        term notes, current portion
                   500,000,000 499,000,000 499,000,000 499,000,000                                         
        convertible senior notes, current portion
                 750,000,000 749,000,000 748,000,000 747,000,000 746,000,000     488,000,000                                     
        (accumulated deficit) retained earnings
               -19,000,000                                                
        retained earnings
                157,000,000 911,000,000 1,145,000,000 1,142,000,000 1,281,000,000 5,097,000,000 5,632,000,000 5,485,000,000 5,372,000,000 5,055,000,000 4,870,000,000 4,723,000,000 4,466,000,000 4,287,000,000 4,240,000,000 4,067,000,000 3,828,000,000 3,594,000,000 3,298,000,000 3,083,000,000 2,872,000,000 2,673,000,000 2,464,000,000 2,256,000,000 2,188,000,000 2,025,000,000 1,897,000,000 1,485,414,000 1,361,652,000 1,232,764,000 1,112,352,000 1,022,765,000 918,288,000 800,111,000 697,864,000 561,206,000 407,926,000 314,437,000 267,832,000 207,855,000 127,187,000 95,837,000 59,960,000 82,547,000 10,640,000   
        convertible senior notes
                      746,000,000 702,000,000 694,000,000 687,000,000 680,000,000                                     
        long-term debt, current portion
                           511,000,000 507,000,000 503,000,000 499,000,000    631,000,000 1,107,000,000 1,107,000,000 625,000,000 620,000,000 10,000,000 2,000,000 5,000,000 1,000,000 1,250,000 1,250,000 511,000  74,929,000 102,166,000 302,447,000 307,427,000 304,256,000 301,119,000 298,018,000 848,016,000 29,288,000 28,810,000 29,731,000 37,641,000 36,967,000 36,307,000 35,660,000 35,025,000 
        long-term debt
                           673,000,000 666,000,000 659,000,000 652,000,000 1,141,000,000 1,131,000,000 1,120,000,000 1,112,000,000 890,000,000 860,000,000 723,000,000 710,000,000 1,182,000,000 1,180,000,000 1,169,000,000 1,055,000,000 1,047,805,000 1,040,765,000 1,031,370,000 1,022,646,000 1,015,649,000 1,007,935,000 1,000,829,000 993,777,000 986,780,000 979,836,000 972,945,000  839,305,000 830,690,000 822,169,000 813,741,000 805,406,000 797,162,000 789,008,000 780,943,000 
        redeemable noncontrolling interests
                                  37,000,000 61,000,000 218,000,000 217,000,000 215,000,000 220,000,000 124,000,000 80,000,000 59,000,000 43,940,000 34,257,000 33,733,000 33,383,000 32,546,000 32,128,000               
        total illumina stockholders’ equity
                               4,613,000,000 4,439,000,000 4,332,000,000 3,985,000,000 3,758,000,000 3,503,000,000 3,257,000,000 3,008,000,000 2,749,000,000 2,855,000,000 2,715,000,000 2,551,000,000 2,197,229,000 2,240,147,000 2,055,771,000 1,991,109,000                 
        noncontrolling interests
                                  85,000,000 87,000,000 91,000,000 94,000,000 65,000,000     73,006,000 79,530,000 84,141,000 79,814,000                 
        build-to-suit lease liability
                                    22,000,000 21,000,000 21,000,000 144,000,000 124,000,000 124,000,000 192,000,000 222,734,000 178,311,000                   
        preferred stock
                                                               
        deferred tax assets, current portion
                                                43,737,000 51,676,000 49,105,000 40,786,000 101,930,000 44,929,000 40,349,000 36,076,000 85,475,000 84,887,000 73,988,000 30,451,000 27,229,000 23,914,000 22,692,000 
        deferred tax assets, long-term portion
                                               134,515,000 86,827,000 66,723,000 63,122,000 49,848,000 39,729,000 70,126,000 101,336,000 88,480,000 43,296,000 9,715,000 21,646,000 40,183,000 54,410,000 48,859,000 26,479,000 
        long-term legal contingencies
                                                     143,597,000 138,780,000 132,933,000        
        conversion option subject to cash settlement
                                                       282,000 810,000 1,394,000 2,484,000 3,158,000 3,818,000 4,465,000 5,100,000 
        accrued legal contingencies
                                                    155,080,000    127,012,000 122,713,000 106,922,000     
        preferred stock: 0.01 par value...
                                                               
      Cashflow Statements:
      Quarterly
      Annual
        Unit: USD2026-03-29 2025-12-28 2025-09-28 2025-06-29 2025-03-30 2024-12-29 2024-09-29 2024-06-30 2024-03-31 2023-12-31 2023-10-01 2023-07-02 2023-04-02 2023-01-01 2022-10-02 2022-07-03 2022-04-03 2022-01-02 2021-10-03 2021-07-04 2021-04-04 2021-01-03 2020-09-27 2020-06-28 2020-03-29 2019-12-29 2019-09-29 2019-06-30 2019-03-31 2018-12-30 2018-09-30 2018-07-01 2018-04-01 2017-12-31 2017-10-01 2017-07-02 2017-04-02 2017-01-01 2016-10-02 2016-07-03 2016-04-03 2016-01-03 2015-09-27 2015-06-28 2015-03-29 2014-12-28 2014-09-28 2014-06-29 2014-03-30 2013-12-29 2013-09-29 2013-06-30 2013-03-31 2012-12-30 2012-09-30 2012-07-01 2012-04-01 
                                                                 
          cash flows from operating activities:
                                                                 
          net income
        134,000,000 334,000,000 150,000,000 235,000,000 131,000,000    -126,000,000    3,000,000 -139,000,000 -3,816,000,000 -535,000,000 86,000,000  317,000,000 186,000,000 147,000,000                       102,247,000 136,658,000 153,280,000 93,489,000 46,605,000 59,977,000 80,661,000 31,357,000 35,877,000 -22,587,000 71,903,000 29,748,000 23,401,000 26,202,000 
          adjustments to reconcile net income to net cash from operating activities:
                                                                 
          depreciation expense
        51,000,000 50,000,000 50,000,000 51,000,000 52,000,000 54,000,000 54,000,000 57,000,000 59,000,000 60,000,000 59,000,000 59,000,000 57,000,000 57,000,000 56,000,000 52,000,000 50,000,000 48,000,000 46,000,000 41,000,000 41,000,000 42,000,000 39,000,000 38,000,000 37,000,000 38,000,000 37,000,000 39,000,000 37,000,000 40,000,000 35,000,000 35,000,000 30,000,000 29,000,000 29,000,000 26,000,000 26,000,000 24,522,000 23,004,000 21,755,000 20,674,000 19,913,000 18,570,000 17,450,000 16,754,000 17,122,000 14,798,000 15,392,000 14,593,000 13,729,000 13,363,000 11,959,000 11,759,000 12,685,000 12,087,000 11,518,000 11,959,000 
          amortization of intangible assets
        18,000,000 16,000,000 17,000,000 17,000,000 17,000,000 17,000,000 16,000,000 48,000,000 49,000,000 49,000,000 49,000,000 49,000,000 50,000,000 49,000,000 47,000,000 42,000,000 41,000,000 41,000,000 19,000,000 8,000,000 7,000,000 8,000,000 8,000,000 8,000,000 7,000,000 7,000,000 10,000,000 10,000,000 10,000,000 10,000,000 10,000,000 10,000,000 9,000,000 10,000,000 12,000,000 12,000,000 12,000,000 12,909,000 12,908,000 12,598,000 12,545,000 12,848,000 14,286,000 13,250,000 13,348,000 12,830,000 11,891,000 12,134,000 13,814,000 13,438,000 13,515,000 11,390,000 8,772,000     
          share-based compensation expense
        60,000,000 63,000,000 70,000,000 69,000,000 73,000,000 79,000,000 83,000,000 112,000,000 96,000,000 94,000,000 87,000,000 106,000,000 93,000,000 100,000,000 83,000,000 91,000,000 92,000,000 98,000,000 509,000,000 80,000,000 67,000,000 78,000,000 61,000,000 16,000,000 39,000,000 49,000,000 46,000,000 48,000,000 51,000,000 47,000,000 48,000,000 50,000,000 48,000,000 41,000,000 34,000,000 39,000,000 50,000,000 27,220,000 34,583,000 31,970,000 35,292,000 35,489,000 32,229,000 32,957,000 31,918,000 38,462,000 44,669,000 35,996,000 33,424,000 29,746,000 27,409,000 24,452,000 24,219,000 24,176,000 23,072,000 24,047,000 23,029,000 
          deferred income taxes
        -3,000,000 37,000,000 41,000,000 25,000,000 16,000,000 49,000,000 19,000,000 -156,000,000 -24,000,000 9,000,000 -78,000,000 53,000,000 -17,000,000 17,000,000 -6,000,000 -13,000,000 -21,000,000 5,000,000 75,000,000 -77,000,000 -79,000,000 67,000,000 3,000,000 76,000,000 -29,000,000 24,000,000 -19,000,000 17,000,000 -11,000,000 14,000,000 -10,000,000 -11,000,000 -11,000,000  -13,000,000 -20,000,000 86,000,000     -3,175,000 3,098,000 27,129,000 53,452,000 69,418,000 -1,084,000 -2,431,000 33,943,000 21,980,000 -29,810,000 7,871,000 -36,704,000 14,741,000 -8,687,000 -22,429,000 -5,323,000 
          net losses on strategic investments
        38,000,000 -191,000,000 -4,000,000   -30,000,000 12,000,000 335,000,000 -5,000,000 1,000,000 20,000,000 3,000,000 16,000,000 43,000,000 3,000,000 32,000,000 44,000,000                                         
          change in fair value of contingent consideration liabilities
        -16,000,000 11,000,000 3,000,000 -21,000,000 -11,000,000 -11,000,000 -49,000,000 -271,000,000 16,000,000 58,000,000 -110,000,000 29,000,000 -1,000,000 25,000,000 -219,000,000                                           
          other
        8,000,000 9,000,000 11,000,000 -2,000,000 3,000,000 22,000,000 -20,000,000 9,000,000 1,000,000 -5,000,000 7,000,000 7,000,000 10,000,000 4,000,000 4,000,000 -1,000,000 52,000,000 -6,000,000 2,000,000 -19,000,000 -19,000,000 -2,000,000 -10,000,000 -2,000,000 9,000,000 -5,000,000 -5,000,000   -6,000,000 3,000,000 3,000,000 -3,000,000 -2,000,000 9,569,000 1,759,000 4,486,000 -1,055,000 4,060,000 4,296,000 636,000 556,000 5,530,000 4,121,000 331,000 -636,000 2,002,000 389,000 -1,965,000 4,107,000     
          changes in operating assets and liabilities:
                                                                 
          accounts receivable
        118,000,000 -121,000,000 -36,000,000 3,000,000 46,000,000 -45,000,000 -52,000,000 -18,000,000 90,000,000 -9,000,000 47,000,000 -79,000,000 1,000,000 -25,000,000 12,000,000 -30,000,000 31,000,000 -39,000,000 -64,000,000 -22,000,000 -39,000,000 -19,000,000 -82,000,000 91,000,000 99,000,000 -29,000,000 -75,000,000 -10,000,000 56,000,000 -81,000,000 -36,000,000 1,000,000 11,000,000 -27,000,000 -13,000,000 -2,000,000 16,000,000 -1,760,000 -8,491,000 26,120,000 -12,630,000 25,396,000 -46,120,000 -15,715,000 -59,474,000 -12,648,000 -20,544,000 34,967,000 -52,156,000 -3,424,000 -24,458,000 5,825,000 6,129,000 2,604,000 -23,832,000 15,945,000 -29,158,000 
          inventory
        -13,000,000 26,000,000 -15,000,000 -38,000,000 10,000,000 28,000,000 -13,000,000 4,000,000 27,000,000 2,000,000 -31,000,000 -18,000,000 -8,000,000 -41,000,000 -52,000,000 -34,000,000 -31,000,000 -18,000,000 -17,000,000 8,000,000 44,000,000 19,000,000 -51,000,000 -24,000,000 58,000,000 3,000,000 -10,000,000 -26,000,000 -13,000,000 -12,000,000 -11,000,000 -17,000,000 -6,000,000 -18,000,000 -10,000,000 1,000,000 12,071,000 -1,171,000 -23,437,000 -17,149,000 -36,947,000 -11,072,000 -18,482,000 -14,044,000 8,151,000 -21,506,000 -13,196,000 -9,991,000 6,615,000 7,961,000 -93,000 -8,266,000 -10,247,000 -8,650,000 -4,969,000 159,000 
          prepaid expenses and other current assets
        -2,000,000 -7,000,000 -12,000,000 5,000,000 6,000,000 -3,000,000 5,000,000 7,000,000 -23,000,000 14,000,000 3,000,000 11,000,000 -17,000,000 6,000,000 6,000,000 -7,000,000 11,000,000 -30,000,000 -40,000,000 -1,000,000 7,000,000 -5,000,000 -18,000,000 17,000,000 -14,000,000 -3,000,000 -17,000,000 6,000,000 -2,000,000 6,000,000 3,000,000 -2,000,000 -6,000,000 9,000,000 3,000,000 2,000,000 -4,776,000 -1,673,000 7,816,000 -2,571,000 -5,894,000 -3,600,000 -225,000 -1,157,000 26,771,000 -18,690,000 -1,587,000 125,000 3,173,000 -740,000 -2,186,000 1,536,000 -1,660,000 -3,253,000 620,000 1,231,000 
          operating lease right-of-use assets and liabilities
        -9,000,000 -9,000,000 -8,000,000 -9,000,000 -8,000,000 -11,000,000 -7,000,000 -7,000,000 -7,000,000 -3,000,000 -3,000,000 -5,000,000 -5,000,000 2,000,000 -3,000,000 -4,000,000 -3,000,000 -4,000,000 -4,000,000 -2,000,000 -3,000,000 -2,000,000 -2,000,000 -6,000,000 -1,000,000 -2,000,000 -2,000,000 -1,000,000                             
          other assets
        -26,000,000 -8,000,000 -10,000,000 -2,000,000 -1,000,000 -1,000,000 -5,000,000 -3,000,000 -6,000,000 -1,000,000 2,000,000 2,000,000 2,000,000 2,000,000 4,000,000 7,000,000 6,000,000 8,000,000 -28,000,000 -3,000,000 -4,000,000 -8,000,000 -2,000,000 -12,000,000 -11,000,000 -1,000,000 -18,000,000 -3,000,000 -8,000,000 -4,000,000 -4,000,000 -1,000,000 -2,000,000 -2,000,000 -1,000,000 -822,000 -238,000 -3,418,000 -2,404,000 -990,000 2,918,000 -816,000 -2,530,000 -30,994,000 11,285,000 -7,575,000 -8,972,000 -12,930,000 -165,000 -1,174,000 -2,088,000 -186,000 -730,000 139,000 -2,126,000 
          accounts payable
        -12,000,000 15,000,000 13,000,000 -11,000,000 -15,000,000 31,000,000 -5,000,000 7,000,000 -37,000,000 6,000,000 -6,000,000 2,000,000 -46,000,000 13,000,000 1,000,000 -13,000,000 -39,000,000 88,000,000 -40,000,000 20,000,000 -8,000,000 42,000,000 11,000,000 3,000,000 -16,000,000 11,000,000 -3,000,000 4,000,000 -47,000,000 32,000,000 12,000,000 -1,000,000 2,000,000 -2,000,000   -3,000,000 5,338,000 -14,956,000 4,592,000 3,057,000 -3,236,000 18,814,000 1,851,000 28,867,000 -16,854,000 864,000 3,824,000 10,060,000 13,265,000 -8,878,000 -10,457,000 8,459,000 -3,322,000 5,400,000 2,775,000 10,259,000 
          accrued liabilities
        -47,000,000  22,000,000 -35,000,000 -56,000,000 -34,000,000 -489,000,000 136,000,000 -53,000,000 40,000,000 -54,000,000 152,000,000 -123,000,000 -7,000,000 -82,000,000 515,000,000 -45,000,000 20,000,000 -81,000,000 57,000,000 105,000,000 61,000,000 -27,000,000 62,000,000 -103,000,000 37,000,000 6,000,000 -17,000,000 -70,000,000 58,000,000 28,000,000 35,000,000 -18,000,000 25,000,000 15,000,000 -11,000,000 52,000,000 33,075,000 -26,052,000 -1,482,000 -29,791,000 70,907,000 33,321,000 26,607,000 -51,044,000 43,304,000 31,739,000 32,006,000 -23,147,000 26,618,000 31,306,000 -4,107,000 -15,267,000 -2,943,000 1,036,000 12,072,000 14,223,000 
          other long-term liabilities
        -10,000,000 17,000,000 -10,000,000 12,000,000 14,000,000 37,000,000 25,000,000 -40,000,000 6,000,000 4,000,000 10,000,000 -26,000,000 11,000,000 3,000,000 -19,000,000 -11,000,000 8,000,000 3,000,000 14,000,000 -4,000,000 -9,000,000 6,000,000 6,000,000 24,000,000 -19,000,000 -2,000,000 5,000,000 -17,000,000 11,000,000 -20,000,000 5,000,000 137,000,000 4,000,000 15,000,000 4,000,000 5,788,000 2,363,000 3,573,000 4,013,000 10,443,000 -6,765,000 24,000 1,521,000 -1,947,000 1,560,000 1,163,000 1,085,000 1,773,000 335,000 334,000 1,374,000 7,747,000 -5,707,000 187,000 4,413,000 
          net cash from operating activities
        289,000,000 321,000,000 284,000,000 234,000,000 240,000,000 364,000,000 316,000,000 80,000,000 77,000,000 224,000,000 139,000,000 105,000,000 10,000,000 147,000,000 -52,000,000 125,000,000 172,000,000 282,000,000 -272,000,000 253,000,000 282,000,000 406,000,000 153,000,000 240,000,000 281,000,000 443,000,000 267,000,000 143,000,000 198,000,000 300,000,000 292,000,000 295,000,000 255,000,000 294,000,000 235,000,000 178,000,000 168,000,000 280,153,000 150,300,000 217,047,000 39,738,000 240,378,000 180,994,000 171,445,000 66,779,000 140,549,000 145,605,000 178,030,000 37,087,000 126,839,000 83,136,000 88,606,000 87,840,000 78,876,000 51,228,000 96,329,000 65,440,000 
          capital expenditures
        -38,000,000 -55,000,000 -30,000,000 -32,000,000 -32,000,000 -31,000,000 -36,000,000 -51,000,000 -45,000,000 -47,000,000 -52,000,000 -88,000,000 -66,000,000 -71,000,000 -61,000,000 -70,000,000 -52,000,000 -44,000,000 -42,000,000 -62,000,000 -48,000,000 -39,000,000 -40,000,000 -57,000,000 -49,000,000 -47,000,000 -56,000,000 -65,000,000 -64,000,000 -77,000,000 -90,000,000 -76,000,000 -82,000,000 -69,000,000 -83,000,000 -81,538,000 -57,122,000 -67,813,000 -53,418,000 -35,486,000 -29,459,000 -41,351,000 -36,551,000 -34,832,000 -28,828,000 -23,324,000 -19,012,000 -27,310,000 -18,930,000 -11,534,000 -21,441,000 -17,101,000 -17,650,000 -20,946,000 -13,084,000 
          free cash flows
        251,000,000 266,000,000 284,000,000 204,000,000 208,000,000 364,000,000 284,000,000 49,000,000 41,000,000 173,000,000 94,000,000 58,000,000 -42,000,000 59,000,000 -118,000,000 54,000,000 111,000,000 212,000,000 -324,000,000 209,000,000 240,000,000 344,000,000 105,000,000 201,000,000 241,000,000 386,000,000 218,000,000 96,000,000 142,000,000 235,000,000 228,000,000 218,000,000 165,000,000 218,000,000 153,000,000 109,000,000 85,000,000 198,615,000 93,178,000 149,234,000 -13,680,000 204,892,000 151,535,000 130,094,000 30,228,000 105,717,000 116,777,000 154,706,000 18,075,000 99,529,000 64,206,000 77,072,000 66,399,000 61,775,000 33,578,000 75,383,000 52,356,000 
          cash flows from investing activities:
                                                                 
          net purchases of property and equipment
        -38,000,000 -55,000,000                                                        
          net sales (purchases) of strategic investments
        87,000,000                                                         
          cash paid for acquisitions and intangible assets, net of cash acquired
        -415,000,000                                                        
          net cash from investing activities
        -366,000,000 108,000,000 -51,000,000 -49,000,000 -63,000,000 -48,000,000 -41,000,000 -41,000,000 -48,000,000 -85,000,000 -53,000,000 -37,000,000 -56,000,000 -102,000,000 -250,000,000 -165,000,000 -74,000,000 -2,448,000,000 3,000,000 1,376,000,000 -34,000,000 -65,000,000 -320,000,000 -135,000,000 -104,000,000 -218,000,000 79,000,000 988,000,000 -348,000,000 -940,000,000 -537,000,000 12,000,000 -315,000,000 -97,000,000 35,000,000 163,000,000 -173,292,000 -341,231,000 43,537,000 -43,553,000 229,398,000 -38,927,000 -142,470,000 -154,147,000 -332,783,000 -44,231,000 114,777,000 -144,387,000 -150,810,000 -101,295,000 247,477,000 -65,021,000 18,611,000 -17,105,000 -9,648,000 -141,870,000 
          cash flows from financing activities:
                                                                 
          common stock repurchases
        -242,000,000 -42,000,000 -130,000,000 -370,000,000 -200,000,000 -17,000,000                -281,000,000 -125,000,000 -142,000,000 -188,000,000 -63,000,000 -198,000,000 -63,000,000 -98,000,000    -75,000,000 -75,000,000 -101,000,000 -136,267,000 -13,075,000   -202,068,000 -37,503,000 -34,753,000 -34,752,000 -72,414,000 -130,017,000 -25,009,000 -25,011,000 -30,013,000 -20,010,000   
          taxes paid related to net share settlement of equity awards
        -33,000,000 -16,000,000 -1,000,000 -1,000,000 -22,000,000 -30,000,000 -1,000,000 -1,000,000 -26,000,000 -2,000,000 -3,000,000 -9,000,000 -35,000,000 -2,000,000 -5,000,000 -12,000,000 -59,000,000 -422,000,000 -6,000,000 -24,000,000 -50,000,000 -3,000,000 -3,000,000 -35,000,000 -52,000,000 -4,000,000 -3,000,000 -23,000,000 -56,000,000 -3,000,000 -2,000,000 -13,000,000 -40,000,000 -4,000,000 -2,000,000 -22,000,000 -23,460,000 -3,573,000 -3,272,000 -69,520,000 -32,055,000 -5,175,000 -6,143,000 -83,839,000 -370,000 -259,000 -583,000 -8,826,000         
          proceeds from issuance of common stock
        24,000,000 16,000,000 1,000,000 27,000,000 20,000,000 36,000,000 30,000,000 37,000,000 30,000,000 33,000,000 1,000,000 28,000,000 31,000,000 27,000,000 2,000,000 32,000,000 29,000,000 3,000,000 27,000,000 1,000,000 23,000,000 1,000,000 21,000,000 8,000,000 32,000,000 9,000,000 22,000,000 505,000 20,595,000 3,508,000 23,053,000 6,171,000 23,155,000 12,786,000 29,727,000 11,595,000 30,581,000 22,107,000 32,045,000 14,234,000 39,147,000 30,309,000 10,770,000 15,651,000 10,687,000 3,898,000 24,122,000 
          net cash from financing activities
        -251,000,000 -63,000,000 -115,000,000 -371,000,000 -195,000,000 -47,000,000 -332,000,000 -226,000,000 35,000,000 -27,000,000 -707,000,000 -3,000,000 -473,000,000 956,000,000 28,000,000 -5,000,000 21,000,000 -129,000,000 -394,000,000 -496,000,000 968,000,000 -331,000,000 -101,000,000 -143,000,000 -191,000,000 -115,000,000 -173,000,000 -549,000,000 -60,000,000 -154,000,000 651,000,000 30,000,000 67,000,000 -109,000,000 -5,000,000 24,000,000 -86,000,000 -163,492,000 34,473,000 -63,345,000 -12,349,000 -253,141,000 -180,897,000 27,810,000 -12,534,000 202,000 55,495,000 -136,521,000 -85,924,000 43,556,000 -75,053,000 5,784,000 -13,006,000 -6,042,000 -8,065,000 -30,264,000 33,616,000 
          effect of exchange rate changes on cash and cash equivalents
        -1,000,000 2,000,000 -2,000,000 7,000,000 4,000,000 -11,000,000 6,000,000 -1,000,000 -4,000,000  -5,000,000 -6,000,000 2,000,000 10,000,000 -15,000,000   -1,000,000   -3,000,000   2,000,000 -6,000,000 3,000,000    -1,000,000 -4,000,000 1,000,000 1,000,000 2,000,000 1,000,000 1,000,000 -3,550,000 -507,000 -487,000 2,304,000 606,000 -698,000 735,000 -2,715,000 -1,709,000 -2,195,000 422,000 100,000 216,000 1,437,000 -1,338,000 -712,000 -553,000 619,000 -199,000 30,000 
          net decrease in cash and cash equivalents
        -329,000,000  116,000,000    -51,000,000                                  -13,860,000   57,520,000 -102,617,000             
          cash and cash equivalents at beginning of period
        1,418,000,000  1,127,000,000  1,048,000,000  2,011,000,000  1,232,000,000  1,810,000,000  2,042,000,000  1,144,000,000  1,225,000,000  735,000,000  768,770,000  636,154,000  711,637,000  433,981,000  302,978,000 
          cash and cash equivalents at end of period
        1,089,000,000  116,000,000 -179,000,000 1,113,000,000  -51,000,000 -188,000,000 1,108,000,000  -626,000,000 59,000,000 1,494,000,000  -289,000,000 -62,000,000 1,351,000,000  -3,116,000,000 -237,000,000 4,433,000,000  -9,000,000 -221,000,000 1,991,000,000  -128,000,000 -327,000,000 2,270,000,000  2,000,000 -216,000,000 1,560,000,000  135,000,000 238,000,000 981,000,000  -156,965,000 196,752,000 754,910,000  -39,528,000 57,520,000 533,537,000  154,674,000 156,708,000 518,513,000  -91,775,000 340,529,000 443,082,000  26,677,000 56,218,000 260,194,000 
          goodwill and intangible impairment
                                                               
          property and equipment and right-of-use asset impairment
            14,000,000 32,000,000 44,000,000                                                
          non-cash charitable contribution
                                                                 
          gain on helix contingent value right
              -4,000,000 -8,000,000 -3,000,000    -3,000,000    -5,000,000                                         
          cash received for helix contingent value right
                                                                
          payments on contingent consideration liabilities
                                                             
          proceeds from debt, net of issuance costs
                                                                
          payments on debt obligations
                                                                
          grail cash deconsolidated as a result of spin-off
                                                               
          net increase in cash and cash equivalents
            -14,000,000    60,000,000   59,000,000 -517,000,000   -62,000,000 119,000,000   -237,000,000 2,623,000,000 49,000,000 -9,000,000 -221,000,000 -51,000,000 227,000,000 -128,000,000 -327,000,000 1,126,000,000 -202,000,000 2,000,000 -216,000,000 335,000,000 -129,000,000 135,000,000 238,000,000 246,000,000 -60,181,000 -156,965,000   217,241,000    -193,741,000 154,674,000 156,708,000 -193,124,000 19,801,000 -91,775,000 340,529,000 9,101,000 90,892,000 26,677,000 56,218,000 -42,784,000 
          cash and cash equivalents at beginning of year
                                                                 
          cash and cash equivalents at end of year
                                                                 
          supplemental cash flow information:
                                                                 
          cash paid for interest
                                                                 
          cash paid for income taxes
                                                                 
          cash paid for operating lease liabilities
                                 21,000,000 21,000,000 21,000,000 21,000,000                             
          purchases of property and equipment included in accounts payable and accrued liabilities
                                                                 
          grail net assets, excluding cash and cash equivalents, deconsolidated as a result of spin-off
                                                               
          net purchases of strategic investments
             -19,000,000                -12,000,000 -5,000,000   -5,000,000 -2,000,000 -10,000,000 -3,000,000 -3,000,000 -3,000,000 -6,000,000 -3,000,000 -4,000,000 -18,000,000 -7,000,000 -4,767,000                    
          cash paid for acquisitions and intangible assets, net of cash required
                                                                 
          purchases of property and equipment
           -30,000,000 -32,000,000  -32,000,000 -31,000,000 -36,000,000 -51,000,000 -45,000,000 -47,000,000 -52,000,000 -88,000,000 -66,000,000 -71,000,000 -61,000,000 -70,000,000 -52,000,000 -44,000,000 -42,000,000 -62,000,000 -48,000,000 -39,000,000 -40,000,000 -57,000,000 -49,000,000 -47,000,000 -56,000,000 -65,000,000 -64,000,000 -77,000,000 -90,000,000 -76,000,000 -82,000,000 -69,000,000 -83,000,000 -81,538,000 -57,122,000 -67,813,000 -53,418,000 -35,486,000 -29,459,000 -41,351,000 -36,551,000 -34,832,000 -28,828,000 -23,324,000 -19,012,000 -27,310,000 -18,930,000 -11,534,000 -21,441,000 -17,101,000 -17,650,000 -20,946,000 -13,084,000 
          purchases of strategic investments
           -19,000,000 -24,000,000   -10,000,000 -12,000,000  -8,000,000 -8,000,000 -3,000,000  -4,000,000 -9,000,000 -13,000,000 -8,000,000 -32,000,000 -9,000,000 -3,000,000                              399,000   -908,000 -7,530,000 -7,500,000 
          cash paid for intangible assets
           -7,000,000                                   -125,000   -29,500,000 -6,095,000 -625,000 -8,499,000 -2,000 -2,342,000 -501,000 -899,000    
          borrowings on delayed draw term loan, net of issuance costs
                                                                 
          net gains on strategic investments
            -32,000,000                                                     
          net loss
             187,000,000 704,000,000    -755,000,000                                               
          adjustments to reconcile net loss to net cash from operating activities:
                                                                 
          loss on helix contingent value right
                 -2,000,000 -5,000,000   -1,000,000 5,000,000                                           
          goodwill and intangible (ipr&d) impairment
               6,000,000                                                
          sales of strategic investments
                        78,000,000 136,000,000 84,000,000                                     
          cash paid for intangible asset
                 -1,000,000                                            
          debt issuance costs paid for credit facility
                 -1,000,000                                             
          payments on term notes
                   -500,000,000                                             
          payments on financing obligations
                                -549,000,000 -1,000,000 -1,000,000 -1,000,000 -2,000,000 -2,000,000 -1,000,000 -5,000,000 -1,000,000 4,625,000 1,050,000 4,103,000 -75,675,000 -28,745,000 -207,543,000 -8,550,000 -114,000 -111,000 -133,000 -93,000 -29,654,000         
          accretion of debt discount on convertible senior notes
                         6,000,000 7,000,000                                       
          gain on previously held investment in grail
                         1,000,000                                        
          gain on exchange of grail contingent value rights
                                                                 
          payment of accreted debt discount
                                                              
          gain on derivative assets related to terminated acquisition
                                                                 
          unrealized loss on foreign exchange translation
                 1,000,000                                                
          maturities of available-for-sale securities
                         331,000,000 166,000,000 109,000,000 111,000,000 107,000,000 125,000,000 58,000,000 173,000,000 1,031,000,000 150,000,000 154,000,000 141,000,000 415,000,000 140,000,000 85,000,000 48,000,000 48,000,000 -8,648,000 35,615,000 36,220,000 76,455,000 104,295,000 94,317,000 53,048,000 42,564,000 32,000,000 25,586,000 48,568,000 44,075,000 165,966,000 11,900,000 44,772,000 66,559,000 37,078,000 28,200,000 78,546,000 21,600,000 
          purchases of available-for-sale securities
                         -77,000,000 -1,045,000,000 -210,000,000 -291,000,000 -256,000,000 -250,000,000 -367,000,000 -276,000,000 -117,000,000 -507,000,000 -1,215,000,000 -539,000,000 -598,000,000 -383,000,000 -273,000,000 -25,000,000 -61,000,000 -215,305,000 -376,517,000 -217,665,000 -84,882,000 -83,160,000 -135,437,000 -253,042,000 -325,383,000 -362,552,000 -69,826,000 -105,619,000 -253,255,000 -185,489,000 -21,013,000 -60,019,000 -97,480,000 -123,125,000 -240,112,000 -230,589,000 -331,652,000 
          sales of available-for-sale securities
                         1,031,000,000 919,000,000 92,000,000 101,000,000 186,000,000 101,000,000 142,000,000 268,000,000 118,000,000 77,000,000 188,000,000 44,000,000 288,000,000 8,000,000 175,000,000 99,000,000 40,000,000 136,966,000 70,987,000 296,290,000 39,009,000 247,177,000 71,904,000 111,291,000 152,156,000 67,101,000 33,290,000 202,234,000 89,030,000 -99,064,000 18,668,000 281,076,000 322,955,000 66,747,000 306,942,000 170,871,000 188,766,000 
          net (purchases) sales of strategic investments
                                                                 
          cash received for derivative assets related to terminated acquisition
                                                                 
          net cash paid for acquisitions
                       -2,364,000,000                34,000 -17,875,000 -1,355,000       -86,023,000 -92,317,000 -50,000 -345,111,000    
          net proceeds from issuance of debt
                         988,000,000                                     
          see accompanying notes to consolidated financial statements.
                                                                 
          impairment of long-lived assets
                                                                 
          goodwill impairment
                                                                
          loss on derivative assets related to terminated acquisition
                         -26,000,000 9,000,000 12,000,000 95,000,000                                 
          cash received (paid for) derivative assets related to terminated acquisition
                         52,000,000                                     
          payments on convertible senior notes
                         -490,000,000 -27,000,000                                     
          change in fair value of contingent consideration liability
                        -49,000,000                                         
          consolidated net income
                             257,000,000 179,000,000 47,000,000 173,000,000 239,000,000 234,000,000 293,000,000 224,000,000 197,000,000 188,000,000 200,000,000 197,000,000 57,000,000 153,000,000 120,000,000 348,000,000 107,542,000 116,935,000 116,394,000 87,219,000 102,864,000                
          payment of accreted debt discount on convertible senior notes
                                                                 
          gains on strategic investments
                                                                 
          gains on deconsolidations
                                                                 
          deconsolidation of helix cash
                                                                
          proceeds from the deconsolidation of grail
                                                                 
          losses on equity securities
                          -41,000,000                                       
          change in fair value of contingent consideration
                                                 325,000 1,109,000 2,329,000 -9,887,000 -2,398,000 333,000 -1,531,000 -1,760,000 -7,753,000 -5,769,000 -5,726,000 464,000 262,000 -1,104,000 1,080,000 1,737,000 
          accretion of debt discount
                            10,000,000 11,000,000 10,000,000 9,000,000 10,000,000 10,000,000 9,000,000 13,000,000 14,000,000 15,000,000 10,000,000 8,000,000 8,000,000 7,000,000 8,000,000 8,000,000 7,000,000 7,390,000 7,333,000 7,278,000 7,731,000 8,689,000 9,452,000 10,207,000 10,169,000 10,080,000 9,992,000 9,005,000 8,992,000 9,142,000 9,063,000 9,023,000 9,009,000 8,904,000 8,802,000 8,699,000 8,599,000 
          losses on marketable equity securities
                            72,000,000                                     
          unrealized gains on marketable equity securities
                             -142,000,000 -59,000,000 -66,000,000 -3,000,000 4,000,000 47,000,000                               
          gains on deconsolidation
                                                               
          cash paid for derivative assets related to terminated acquisition
                             -132,000,000                                 
          contributions from noncontrolling interest owners
                                     31,000,000 61,000,000 43,000,000 20,000,000 16,000,000 9,000,000 80,000,000                
          net cash paid for acquisition
                                                                 
          gain on deconsolidation of grail
                                    -15,000,000     -453,000,000                     
          loss on continuation advances
                                                                 
          impairment of intangible assets
                                         23,000,000                     
          cash paid for continuation advances
                                                                 
          deconsolidation of helix and grail cash
                                                                 
          payments on acquisition-related contingent consideration liability
                                                                 
          proceeds from deconsolidation of grail
                                  15,000,000                             
          proceeds from sale of grail securities
                                         278,000,000                     
          deconsolidation of grail cash
                                         -52,000,000                     
          proceeds from early exercise of equity awards from a subsidiary
                                             707,000 804,000                   
          payments on acquisition related contingent consideration liability
                                            -29,200,000 -1,400,000        -3,985,000     
          proceeds from issuance of debt
                                           2,958,000                   
          deferred income tax expense
                                             36,023,000 29,710,000 34,029,000 -6,200,000                 
          cost-method investment gain
                                                 -119,000 -2,900,000 -12,582,000             
          gain on litigation settlement
                                                                 
          illumina, inc.consolidated statements of cash flows —
                                                                 
          loss on extinguishment of debt
                                                 325,000 3,504,000             
          incremental tax benefit related to share-based compensation
                                             18,602,000 -25,714,000 -25,227,000 -58,993,000 -4,956,000 -15,541,000 -29,717,000 -76,445,000 -23,840,000 -25,306,000 -26,805,000 -50,528,000 -29,453,000 -12,381,000 -9,566,000 -5,278,000     
          repurchase of convertible notes
                                                                 
          net (purchases of) sales proceeds from strategic investments
                                               -3,529,000 -2,842,000     -5,000,000            
          (gain) impairment related to discontinued product line
                                                                 
          change in estimated cease-use loss
                                                 436,000 -5,226,000 1,480,000 699,000 1,294,000 870,000           
          accrued legal contingencies
                                                 4,000,000    -45,717,000 11,483,000 4,817,000 5,847,000  4,299,000 15,791,000 106,922,000     
          proceeds from issuance of convertible notes
                                                               
          payments on retirement of warrants
                                                                 
          net sales proceeds from (purchases of) strategic investments
                                                  -5,026,000 -12,141,000 13,067,000             
          repurchases of convertible notes
                                                                
          contingent compensation expense
                                                     68,000 68,000 68,000 2,417,000 4,169,000 1,358,000 1,358,000 1,393,000 2,257,000 1,084,000 44,000 2,921,000 
          cost-method investment related gain
                                                        -55,244,000 -6,113,000     
          unsettled short-term investments purchase
                                                                 
          impairments
                                                                
          (purchases of) sales proceeds from strategic investments
                                                       -7,082,000 -4,600,000         
          change in facility exit obligation
                                                         2,856,000        
          long-term legal contingencies
                                                                 
          proceeds from (purchases of) strategic investments
                                                                 
          payments on current portion of long-term financing obligations
                                                                 
          (payments for) proceeds from warrant settlements
                                                                 
          proceeds from sale of strategic investment
                                                          3,000 9,998,000     
          payments on long-term financing obligations
                                                          -1,581,000       
          impairment of in-process research and development
                                                               
          payments on long-term financing obligation
                                                            -58,000     
          amortization of acquired intangible assets
                                                             5,411,000 3,740,000 3,195,000 3,195,000 
          cease-use loss
                                                             2,883,000    
          cost-method investment related loss
                                                                 
          recovery of previously impaired note receivable
                                                                 
          sales and maturities of trading securities
                                                                 
          payments on current portion of long-term debt
                                                                 
          proceeds from the exercise of warrants
                                                                 
          incremental tax benefit related to stock options exercised
                                                              -1,258,000 -1,711,000 -9,494,000 
          other non-cash adjustments
                                                              1,586,000 3,108,000 2,484,000 
          unrealized (gain) loss on foreign exchange
                                                                 
          cash paid in business combination milestones
                                                                
          unrealized gain on foreign exchange
                                                               -2,830,000 1,130,000 
          proceeds from exercises of warrants