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Illumina Quarterly Cash Flow Statements Chart

Quarterly
 | 
Annual
 
 Operating Cash Flow  
 Investing Cash Flow  
 Financing Cash Flow  
 Free Cash Flow  
 Capital Expenditure  
20200927 20210103 20210404 20210704 20211003 20220102 20220403 20220703 20221002 20230101 20230402 20230702 20231001 20231231 20240331 20240630 20240929 20241229 20250330 20250629 -324-219.71-115.43-11.1493.14197.43301.71406Milllion

Illumina Quarterly Cash Flow Statements Table

Quarterly
 | 
Annual
 
Unit: USD2025-06-29 2025-03-30 2024-12-29 2024-09-29 2024-06-30 2024-03-31 2023-12-31 2023-10-01 2023-07-02 2023-04-02 2023-01-01 2022-10-02 2022-07-03 2022-04-03 2022-01-02 2021-10-03 2021-07-04 2021-04-04 2021-01-03 2020-09-27 2020-06-28 2020-03-29 2019-12-29 2019-09-29 2019-06-30 2019-03-31 2018-12-30 2018-09-30 2018-07-01 2018-04-01 2017-12-31 2017-10-01 2017-07-02 2017-04-02 2017-01-01 2016-10-02 2016-07-03 2016-04-03 2016-01-03 2015-09-27 2015-06-28 2015-03-29 2014-12-28 2014-09-28 2014-06-29 2014-03-30 2013-12-29 2013-09-29 2013-06-30 2013-03-31 2012-12-30 2012-09-30 2012-07-01 2012-04-01 
                                                        
  cash flows from operating activities:                                                      
  net income235,000,000 131,000,000 187,000,000 704,000,000 -1,988,000,000 -126,000,000 -175,000,000 -755,000,000 -234,000,000 3,000,000 -139,000,000 -3,816,000,000 -535,000,000 86,000,000  317,000,000 186,000,000 147,000,000                       102,247,000 136,658,000 153,280,000 93,489,000 46,605,000 59,977,000 80,661,000 31,357,000 35,877,000 -22,587,000 71,903,000 29,748,000 23,401,000 26,202,000 
  adjustments to reconcile net income to net cash from operating activities:                                                      
  depreciation expense51,000,000 52,000,000 54,000,000 54,000,000 57,000,000 59,000,000 60,000,000 59,000,000 59,000,000 57,000,000 57,000,000 56,000,000 52,000,000 50,000,000 48,000,000 46,000,000 41,000,000 41,000,000 42,000,000 39,000,000 38,000,000 37,000,000 38,000,000 37,000,000 39,000,000 37,000,000 40,000,000 35,000,000 35,000,000 30,000,000 29,000,000 29,000,000 26,000,000 26,000,000 24,522,000 23,004,000 21,755,000 20,674,000 19,913,000 18,570,000 17,450,000 16,754,000 17,122,000 14,798,000 15,392,000 14,593,000 13,729,000 13,363,000 11,959,000 11,759,000 12,685,000 12,087,000 11,518,000 11,959,000 
  amortization of intangible assets17,000,000 17,000,000 17,000,000 16,000,000 48,000,000 49,000,000 49,000,000 49,000,000 49,000,000 50,000,000 49,000,000 47,000,000 42,000,000 41,000,000 41,000,000 19,000,000 8,000,000 7,000,000 8,000,000 8,000,000 8,000,000 7,000,000 7,000,000 10,000,000 10,000,000 10,000,000 10,000,000 10,000,000 10,000,000 9,000,000 10,000,000 12,000,000 12,000,000 12,000,000 12,909,000 12,908,000 12,598,000 12,545,000 12,848,000 14,286,000 13,250,000 13,348,000 12,830,000 11,891,000 12,134,000 13,814,000 13,438,000 13,515,000 11,390,000 8,772,000     
  share-based compensation expense69,000,000 73,000,000 79,000,000 83,000,000 112,000,000 96,000,000 94,000,000 87,000,000 106,000,000 93,000,000 100,000,000 83,000,000 91,000,000 92,000,000 98,000,000 509,000,000 80,000,000 67,000,000 78,000,000 61,000,000 16,000,000 39,000,000 49,000,000 46,000,000 48,000,000 51,000,000 47,000,000 48,000,000 50,000,000 48,000,000 41,000,000 34,000,000 39,000,000 50,000,000 27,220,000 34,583,000 31,970,000 35,292,000 35,489,000 32,229,000 32,957,000 31,918,000 38,462,000 44,669,000 35,996,000 33,424,000 29,746,000 27,409,000 24,452,000 24,219,000 24,176,000 23,072,000 24,047,000 23,029,000 
  deferred income taxes25,000,000 16,000,000 49,000,000 19,000,000 -156,000,000 -24,000,000 9,000,000 -78,000,000 53,000,000 -17,000,000 17,000,000 -6,000,000 -13,000,000 -21,000,000 5,000,000 75,000,000 -77,000,000 -79,000,000 67,000,000 3,000,000 76,000,000 -29,000,000 24,000,000 -19,000,000 17,000,000 -11,000,000 14,000,000 -10,000,000 -11,000,000 -11,000,000  -13,000,000 -20,000,000 86,000,000     -3,175,000 3,098,000 27,129,000 53,452,000 69,418,000 -1,084,000 -2,431,000 33,943,000 21,980,000 -29,810,000 7,871,000 -36,704,000 14,741,000 -8,687,000 -22,429,000 -5,323,000 
  net (gains) losses on strategic investments     -5,000,000                                                 
  change in fair value of contingent consideration liabilities-21,000,000 -11,000,000 -11,000,000 -49,000,000 -271,000,000 16,000,000 58,000,000 -110,000,000 29,000,000 -1,000,000 25,000,000 -219,000,000                                           
  gain on helix contingent value right   -4,000,000 -8,000,000 -3,000,000    -3,000,000 -1,000,000 5,000,000 8,000,000 -5,000,000                                         
  property and equipment and right-of-use asset impairment  14,000,000 32,000,000 44,000,000                                                
  goodwill and intangible impairment                                                      
  other11,000,000 -2,000,000 3,000,000 22,000,000 -20,000,000 9,000,000 1,000,000 -5,000,000 7,000,000 7,000,000 10,000,000 4,000,000 4,000,000 -1,000,000 52,000,000 -6,000,000 2,000,000 -19,000,000 -19,000,000 -2,000,000 -10,000,000 -2,000,000 9,000,000 -5,000,000 -5,000,000   -6,000,000 3,000,000 3,000,000 -3,000,000 -2,000,000 9,569,000 1,759,000 4,486,000 -1,055,000 4,060,000 4,296,000 636,000 556,000 5,530,000 4,121,000 331,000 -636,000 2,002,000 389,000 -1,965,000 4,107,000     
  changes in operating assets and liabilities:                                                      
  accounts receivable3,000,000 46,000,000 -45,000,000 -52,000,000 -18,000,000 90,000,000 -9,000,000 47,000,000 -79,000,000 1,000,000 -25,000,000 12,000,000 -30,000,000 31,000,000 -39,000,000 -64,000,000 -22,000,000 -39,000,000 -19,000,000 -82,000,000 91,000,000 99,000,000 -29,000,000 -75,000,000 -10,000,000 56,000,000 -81,000,000 -36,000,000 1,000,000 11,000,000 -27,000,000 -13,000,000 -2,000,000 16,000,000 -1,760,000 -8,491,000 26,120,000 -12,630,000 25,396,000 -46,120,000 -15,715,000 -59,474,000 -12,648,000 -20,544,000 34,967,000 -52,156,000 -3,424,000 -24,458,000 5,825,000 6,129,000 2,604,000 -23,832,000 15,945,000 -29,158,000 
  inventory-38,000,000 10,000,000 28,000,000 -13,000,000 4,000,000 27,000,000 2,000,000 -31,000,000 -18,000,000 -8,000,000 -41,000,000 -52,000,000 -34,000,000 -31,000,000 -18,000,000 -17,000,000 8,000,000 44,000,000 19,000,000 -51,000,000 -24,000,000 58,000,000 3,000,000 -10,000,000 -26,000,000 -13,000,000 -12,000,000 -11,000,000 -17,000,000 -6,000,000 -18,000,000 -10,000,000 1,000,000 12,071,000 -1,171,000 -23,437,000 -17,149,000 -36,947,000 -11,072,000 -18,482,000 -14,044,000 8,151,000 -21,506,000 -13,196,000 -9,991,000 6,615,000 7,961,000 -93,000 -8,266,000 -10,247,000 -8,650,000 -4,969,000 159,000 
  prepaid expenses and other current assets5,000,000 6,000,000 -3,000,000 5,000,000 7,000,000 -23,000,000 14,000,000 3,000,000 11,000,000 -17,000,000 6,000,000 6,000,000 -7,000,000 11,000,000 -30,000,000 -40,000,000 -1,000,000 7,000,000 -5,000,000 -18,000,000 17,000,000 -14,000,000 -3,000,000 -17,000,000 6,000,000 -2,000,000 6,000,000 3,000,000 -2,000,000 -6,000,000 9,000,000 3,000,000 2,000,000 -4,776,000 -1,673,000 7,816,000 -2,571,000 -5,894,000 -3,600,000 -225,000 -1,157,000 26,771,000 -18,690,000 -1,587,000 125,000 3,173,000 -740,000 -2,186,000 1,536,000 -1,660,000 -3,253,000 620,000 1,231,000 
  operating lease right-of-use assets and liabilities-9,000,000 -8,000,000 -11,000,000 -7,000,000 -7,000,000 -7,000,000 -3,000,000 -3,000,000 -5,000,000 -5,000,000 2,000,000 -3,000,000 -4,000,000 -3,000,000 -4,000,000 -4,000,000 -2,000,000 -3,000,000 -2,000,000 -2,000,000 -6,000,000 -1,000,000 -2,000,000 -2,000,000 -1,000,000                             
  other assets-2,000,000 -1,000,000 -1,000,000 -5,000,000 -3,000,000 -6,000,000 -1,000,000 2,000,000 2,000,000 2,000,000 2,000,000 4,000,000 7,000,000 6,000,000 8,000,000 -28,000,000 -3,000,000 -4,000,000 -8,000,000 -2,000,000 -12,000,000 -11,000,000 -1,000,000 -18,000,000 -3,000,000 -8,000,000 -4,000,000 -4,000,000 -1,000,000 -2,000,000 -2,000,000 -1,000,000 -822,000 -238,000 -3,418,000 -2,404,000 -990,000 2,918,000 -816,000 -2,530,000 -30,994,000 11,285,000 -7,575,000 -8,972,000 -12,930,000 -165,000 -1,174,000 -2,088,000 -186,000 -730,000 139,000 -2,126,000 
  accounts payable-11,000,000 -15,000,000 31,000,000 -5,000,000 7,000,000 -37,000,000 6,000,000 -6,000,000 2,000,000 -46,000,000 13,000,000 1,000,000 -13,000,000 -39,000,000 88,000,000 -40,000,000 20,000,000 -8,000,000 42,000,000 11,000,000 3,000,000 -16,000,000 11,000,000 -3,000,000 4,000,000 -47,000,000 32,000,000 12,000,000 -1,000,000 2,000,000 -2,000,000   -3,000,000 5,338,000 -14,956,000 4,592,000 3,057,000 -3,236,000 18,814,000 1,851,000 28,867,000 -16,854,000 864,000 3,824,000 10,060,000 13,265,000 -8,878,000 -10,457,000 8,459,000 -3,322,000 5,400,000 2,775,000 10,259,000 
  accrued liabilities-35,000,000 -56,000,000 -34,000,000 -489,000,000 136,000,000 -53,000,000 40,000,000 -54,000,000 152,000,000 -123,000,000 -7,000,000 -82,000,000 515,000,000 -45,000,000 20,000,000 -81,000,000 57,000,000 105,000,000 61,000,000 -27,000,000 62,000,000 -103,000,000 37,000,000 6,000,000 -17,000,000 -70,000,000 58,000,000 28,000,000 35,000,000 -18,000,000 25,000,000 15,000,000 -11,000,000 52,000,000 33,075,000 -26,052,000 -1,482,000 -29,791,000 70,907,000 33,321,000 26,607,000 -51,044,000 43,304,000 31,739,000 32,006,000 -23,147,000 26,618,000 31,306,000 -4,107,000 -15,267,000 -2,943,000 1,036,000 12,072,000 14,223,000 
  other long-term liabilities12,000,000 14,000,000 37,000,000 25,000,000 -40,000,000 6,000,000 4,000,000 10,000,000 -26,000,000 11,000,000 3,000,000 -19,000,000 -11,000,000 8,000,000 3,000,000 14,000,000 -4,000,000 -9,000,000 6,000,000 6,000,000 24,000,000 -19,000,000 -2,000,000 5,000,000 -17,000,000 11,000,000 -20,000,000 5,000,000 137,000,000 4,000,000 15,000,000 4,000,000 5,788,000 2,363,000 3,573,000 4,013,000 10,443,000 -6,765,000 24,000 1,521,000 -1,947,000 1,560,000 1,163,000 1,085,000 1,773,000 335,000 334,000 1,374,000 7,747,000 -5,707,000 187,000 4,413,000 
  net cash from operating activities234,000,000 240,000,000 364,000,000 316,000,000 80,000,000 77,000,000 224,000,000 139,000,000 105,000,000 10,000,000 147,000,000 -52,000,000 125,000,000 172,000,000 282,000,000 -272,000,000 253,000,000 282,000,000 406,000,000 153,000,000 240,000,000 281,000,000 443,000,000 267,000,000 143,000,000 198,000,000 300,000,000 292,000,000 295,000,000 255,000,000 294,000,000 235,000,000 178,000,000 168,000,000 280,153,000 150,300,000 217,047,000 39,738,000 240,378,000 180,994,000 171,445,000 66,779,000 140,549,000 145,605,000 178,030,000 37,087,000 126,839,000 83,136,000 88,606,000 87,840,000 78,876,000 51,228,000 96,329,000 65,440,000 
  capex-30,000,000 -32,000,000 -32,000,000 -31,000,000 -36,000,000 -51,000,000 -45,000,000 -47,000,000 -52,000,000 -88,000,000 -66,000,000 -71,000,000 -61,000,000 -70,000,000 -52,000,000 -44,000,000 -42,000,000 -62,000,000 -48,000,000 -39,000,000 -40,000,000 -57,000,000 -49,000,000 -47,000,000 -56,000,000 -65,000,000 -64,000,000 -77,000,000 -90,000,000 -76,000,000 -82,000,000 -69,000,000 -83,000,000 -81,538,000 -57,122,000 -67,813,000 -53,418,000 -35,486,000 -29,459,000 -41,351,000 -36,551,000 -34,832,000 -28,828,000 -23,324,000 -19,012,000 -27,310,000 -18,930,000 -11,534,000 -21,441,000 -17,101,000 -17,650,000 -20,946,000 -13,084,000 
  free cash flows204,000,000 208,000,000 364,000,000 284,000,000 49,000,000 41,000,000 173,000,000 94,000,000 58,000,000 -42,000,000 59,000,000 -118,000,000 54,000,000 111,000,000 212,000,000 -324,000,000 209,000,000 240,000,000 344,000,000 105,000,000 201,000,000 241,000,000 386,000,000 218,000,000 96,000,000 142,000,000 235,000,000 228,000,000 218,000,000 165,000,000 218,000,000 153,000,000 109,000,000 85,000,000 198,615,000 93,178,000 149,234,000 -13,680,000 204,892,000 151,535,000 130,094,000 30,228,000 105,717,000 116,777,000 154,706,000 18,075,000 99,529,000 64,206,000 77,072,000 66,399,000 61,775,000 33,578,000 75,383,000 52,356,000 
  cash flows from investing activities:                                                      
  purchases of property and equipment-30,000,000 -32,000,000  -32,000,000 -31,000,000 -36,000,000 -51,000,000 -45,000,000 -47,000,000 -52,000,000 -88,000,000 -66,000,000 -71,000,000 -61,000,000 -70,000,000 -52,000,000 -44,000,000 -42,000,000 -62,000,000 -48,000,000 -39,000,000 -40,000,000 -57,000,000 -49,000,000 -47,000,000 -56,000,000 -65,000,000 -64,000,000 -77,000,000 -90,000,000 -76,000,000 -82,000,000 -69,000,000 -83,000,000 -81,538,000 -57,122,000 -67,813,000 -53,418,000 -35,486,000 -29,459,000 -41,351,000 -36,551,000 -34,832,000 -28,828,000 -23,324,000 -19,012,000 -27,310,000 -18,930,000 -11,534,000 -21,441,000 -17,101,000 -17,650,000 -20,946,000 -13,084,000 
  purchases of strategic investments-19,000,000 -24,000,000   -10,000,000 -12,000,000  -8,000,000 -8,000,000 -3,000,000  -4,000,000 -9,000,000 -13,000,000 -8,000,000 -32,000,000 -9,000,000 -3,000,000                              399,000   -908,000 -7,530,000 -7,500,000 
  cash paid for intangible assets-7,000,000                                   -125,000   -29,500,000 -6,095,000 -625,000 -8,499,000 -2,000 -2,342,000 -501,000 -899,000    
  net cash from investing activities-49,000,000 -63,000,000 -48,000,000 -41,000,000 -41,000,000 -48,000,000 -85,000,000 -53,000,000 -37,000,000 -56,000,000 -102,000,000 -250,000,000 -165,000,000 -74,000,000 -2,448,000,000 3,000,000 1,376,000,000 -34,000,000 -65,000,000 -320,000,000 -135,000,000 -104,000,000 -218,000,000 79,000,000 988,000,000 -348,000,000 -940,000,000 -537,000,000 12,000,000 -315,000,000 -97,000,000 35,000,000 163,000,000 -173,292,000 -341,231,000 43,537,000 -43,553,000 229,398,000 -38,927,000 -142,470,000 -154,147,000 -332,783,000 -44,231,000 114,777,000 -144,387,000 -150,810,000 -101,295,000 247,477,000 -65,021,000 18,611,000 -17,105,000 -9,648,000 -141,870,000 
  cash flows from financing activities:                                                      
  common stock repurchases-370,000,000 -200,000,000 -17,000,000                -281,000,000 -125,000,000 -142,000,000 -188,000,000 -63,000,000 -198,000,000 -63,000,000 -98,000,000    -75,000,000 -75,000,000 -101,000,000 -136,267,000 -13,075,000   -202,068,000 -37,503,000 -34,753,000 -34,752,000 -72,414,000 -130,017,000 -25,009,000 -25,011,000 -30,013,000 -20,010,000   
  taxes paid related to net share settlement of equity awards-1,000,000 -22,000,000 -30,000,000 -1,000,000 -1,000,000 -26,000,000 -2,000,000 -3,000,000 -9,000,000 -35,000,000 -2,000,000 -5,000,000 -12,000,000 -59,000,000 -422,000,000 -6,000,000 -24,000,000 -50,000,000 -3,000,000 -3,000,000 -35,000,000 -52,000,000 -4,000,000 -3,000,000 -23,000,000 -56,000,000 -3,000,000 -2,000,000 -13,000,000 -40,000,000 -4,000,000 -2,000,000 -22,000,000 -23,460,000 -3,573,000 -3,272,000 -69,520,000 -32,055,000 -5,175,000 -6,143,000 -83,839,000 -370,000 -259,000 -583,000 -8,826,000         
  proceeds from issuance of common stock1,000,000 27,000,000 20,000,000 36,000,000 30,000,000 37,000,000 30,000,000 33,000,000 1,000,000 28,000,000 31,000,000 27,000,000 2,000,000 32,000,000 29,000,000 3,000,000 27,000,000 1,000,000 23,000,000 1,000,000 21,000,000 8,000,000 32,000,000 9,000,000 22,000,000 505,000 20,595,000 3,508,000 23,053,000 6,171,000 23,155,000 12,786,000 29,727,000 11,595,000 30,581,000 22,107,000 32,045,000 14,234,000 39,147,000 30,309,000 10,770,000 15,651,000 10,687,000 3,898,000 24,122,000 
  payments on contingent consideration liabilities                                                    
  grail cash deconsolidated as a result of spin-off                                                    
  borrowings on delayed draw term loan, net of issuance costs                                                      
  net cash from financing activities-371,000,000 -195,000,000 -47,000,000 -332,000,000 -226,000,000 35,000,000 -27,000,000 -707,000,000 -3,000,000 -473,000,000 956,000,000 28,000,000 -5,000,000 21,000,000 -129,000,000 -394,000,000 -496,000,000 968,000,000 -331,000,000 -101,000,000 -143,000,000 -191,000,000 -115,000,000 -173,000,000 -549,000,000 -60,000,000 -154,000,000 651,000,000 30,000,000 67,000,000 -109,000,000 -5,000,000 24,000,000 -86,000,000 -163,492,000 34,473,000 -63,345,000 -12,349,000 -253,141,000 -180,897,000 27,810,000 -12,534,000 202,000 55,495,000 -136,521,000 -85,924,000 43,556,000 -75,053,000 5,784,000 -13,006,000 -6,042,000 -8,065,000 -30,264,000 33,616,000 
  effect of exchange rate changes on cash and cash equivalents7,000,000 4,000,000 -11,000,000 6,000,000 -1,000,000 -4,000,000  -5,000,000 -6,000,000 2,000,000 10,000,000 -15,000,000   -1,000,000   -3,000,000   2,000,000 -6,000,000 3,000,000    -1,000,000 -4,000,000 1,000,000 1,000,000 2,000,000 1,000,000 1,000,000 -3,550,000 -507,000 -487,000 2,304,000 606,000 -698,000 735,000 -2,715,000 -1,709,000 -2,195,000 422,000 100,000 216,000 1,437,000 -1,338,000 -712,000 -553,000 619,000 -199,000 30,000 
  net decrease in cash and cash equivalents   -51,000,000                                  -13,860,000   57,520,000 -102,617,000             
  cash and cash equivalents at beginning of period1,127,000,000  1,048,000,000  2,011,000,000  1,232,000,000  1,810,000,000  2,042,000,000  1,144,000,000  1,225,000,000  735,000,000  768,770,000  636,154,000  711,637,000  433,981,000  302,978,000 
  cash and cash equivalents at end of period-179,000,000 1,113,000,000  -51,000,000 -188,000,000 1,108,000,000  -626,000,000 59,000,000 1,494,000,000  -289,000,000 -62,000,000 1,351,000,000  -3,116,000,000 -237,000,000 4,433,000,000  -9,000,000 -221,000,000 1,991,000,000  -128,000,000 -327,000,000 2,270,000,000  2,000,000 -216,000,000 1,560,000,000  135,000,000 238,000,000 981,000,000  -156,965,000 196,752,000 754,910,000  -39,528,000 57,520,000 533,537,000  154,674,000 156,708,000 518,513,000  -91,775,000 340,529,000 443,082,000  26,677,000 56,218,000 260,194,000 
  supplemental cash flow information:                                                      
  grail net assets, excluding cash and cash equivalents, deconsolidated as a result of spin-off                                                    
  net gains on strategic investments -32,000,000                                                     
  net increase in cash and cash equivalents -14,000,000    60,000,000   59,000,000 -517,000,000   -62,000,000 119,000,000   -237,000,000 2,623,000,000 49,000,000 -9,000,000 -221,000,000 -51,000,000 227,000,000 -128,000,000 -327,000,000 1,126,000,000 -202,000,000 2,000,000 -216,000,000 335,000,000 -129,000,000 135,000,000 238,000,000 246,000,000 -60,181,000 -156,965,000   217,241,000    -193,741,000 154,674,000 156,708,000 -193,124,000 19,801,000 -91,775,000 340,529,000 9,101,000 90,892,000 26,677,000 56,218,000 -42,784,000 
  net incomees on strategic investments  -30,000,000 12,000,000    20,000,000 3,000,000 16,000,000   32,000,000 44,000,000                                         
  (gain) loss on helix contingent value right      -2,000,000 -5,000,000                                               
  goodwill and intangible (ipr&d) impairment    6,000,000                                                
  net purchases of property and equipment                                                      
  net purchases of strategic investments  -19,000,000                -12,000,000 -5,000,000   -5,000,000 -2,000,000 -10,000,000 -3,000,000 -3,000,000 -3,000,000 -6,000,000 -3,000,000 -4,000,000 -18,000,000 -7,000,000 -4,767,000                    
  cash paid for acquisitions and intangible assets, net of cash acquired                                                     
  cash received for helix contingent value right                                                     
  proceeds from debt, net of issuance costs                                                     
  payments on debt obligations                                                     
  cash and cash equivalents at beginning of year                                                      
  cash and cash equivalents at end of year                                                      
  cash paid for interest                                                      
  cash paid for income taxes                                                      
  cash paid for operating lease liabilities                      21,000,000 21,000,000 21,000,000 21,000,000                             
  purchases of property and equipment included in accounts payable and accrued liabilities                                                      
  sales of strategic investments             78,000,000 136,000,000 84,000,000                                     
  cash paid for intangible asset      -1,000,000                                            
  debt issuance costs paid for credit facility      -1,000,000                                             
  payments on term notes        -500,000,000                                             
  payments on financing obligations                     -549,000,000 -1,000,000 -1,000,000 -1,000,000 -2,000,000 -2,000,000 -1,000,000 -5,000,000 -1,000,000 4,625,000 1,050,000 4,103,000 -75,675,000 -28,745,000 -207,543,000 -8,550,000 -114,000 -111,000 -133,000 -93,000 -29,654,000         
  accretion of debt discount on convertible senior notes              6,000,000 7,000,000                                       
  gain on previously held investment in grail              1,000,000                                        
  gain on exchange of grail contingent value rights                                                      
  net incomees (gains) on strategic investments          43,000,000                                            
  payment of accreted debt discount                                                   
  gain on derivative assets related to terminated acquisition                                                      
  unrealized loss on foreign exchange translation      1,000,000                                                
  maturities of available-for-sale securities              331,000,000 166,000,000 109,000,000 111,000,000 107,000,000 125,000,000 58,000,000 173,000,000 1,031,000,000 150,000,000 154,000,000 141,000,000 415,000,000 140,000,000 85,000,000 48,000,000 48,000,000 -8,648,000 35,615,000 36,220,000 76,455,000 104,295,000 94,317,000 53,048,000 42,564,000 32,000,000 25,586,000 48,568,000 44,075,000 165,966,000 11,900,000 44,772,000 66,559,000 37,078,000 28,200,000 78,546,000 21,600,000 
  purchases of available-for-sale securities              -77,000,000 -1,045,000,000 -210,000,000 -291,000,000 -256,000,000 -250,000,000 -367,000,000 -276,000,000 -117,000,000 -507,000,000 -1,215,000,000 -539,000,000 -598,000,000 -383,000,000 -273,000,000 -25,000,000 -61,000,000 -215,305,000 -376,517,000 -217,665,000 -84,882,000 -83,160,000 -135,437,000 -253,042,000 -325,383,000 -362,552,000 -69,826,000 -105,619,000 -253,255,000 -185,489,000 -21,013,000 -60,019,000 -97,480,000 -123,125,000 -240,112,000 -230,589,000 -331,652,000 
  sales of available-for-sale securities              1,031,000,000 919,000,000 92,000,000 101,000,000 186,000,000 101,000,000 142,000,000 268,000,000 118,000,000 77,000,000 188,000,000 44,000,000 288,000,000 8,000,000 175,000,000 99,000,000 40,000,000 136,966,000 70,987,000 296,290,000 39,009,000 247,177,000 71,904,000 111,291,000 152,156,000 67,101,000 33,290,000 202,234,000 89,030,000 -99,064,000 18,668,000 281,076,000 322,955,000 66,747,000 306,942,000 170,871,000 188,766,000 
  net (purchases) sales of strategic investments                                                      
  cash received for derivative assets related to terminated acquisition                                                      
  net cash paid for acquisitions            -2,364,000,000                34,000 -17,875,000 -1,355,000       -86,023,000 -92,317,000 -50,000 -345,111,000    
  net proceeds from issuance of debt              988,000,000                                     
  see accompanying notes to consolidated financial statements.                                                      
  impairment of long-lived assets                                                      
  goodwill impairment                                                     
  (gain) loss on derivative assets related to terminated acquisition              -26,000,000                                     
  cash received (paid for) derivative assets related to terminated acquisition              52,000,000                                     
  payments on convertible senior notes              -490,000,000 -27,000,000                                     
  change in fair value of contingent consideration liability             -49,000,000                                         
  consolidated net income                  257,000,000 179,000,000 47,000,000 173,000,000 239,000,000 234,000,000 293,000,000 224,000,000 197,000,000 188,000,000 200,000,000 197,000,000 57,000,000 153,000,000 120,000,000 348,000,000 107,542,000 116,935,000 116,394,000 87,219,000 102,864,000                
  payment of accreted debt discount on convertible senior notes                                                      
  gains on strategic investments                                                      
  gains on deconsolidations                                                      
  deconsolidation of helix cash                                                     
  proceeds from the deconsolidation of grail                                                      
  losses (gains) on equity securities               -41,000,000                                       
  change in fair value of contingent consideration                                      325,000 1,109,000 2,329,000 -9,887,000 -2,398,000 333,000 -1,531,000 -1,760,000 -7,753,000 -5,769,000 -5,726,000 464,000 262,000 -1,104,000 1,080,000 1,737,000 
  accretion of debt discount                 10,000,000 11,000,000 10,000,000 9,000,000 10,000,000 10,000,000 9,000,000 13,000,000 14,000,000 15,000,000 10,000,000 8,000,000 8,000,000 7,000,000 8,000,000 8,000,000 7,000,000 7,390,000 7,333,000 7,278,000 7,731,000 8,689,000 9,452,000 10,207,000 10,169,000 10,080,000 9,992,000 9,005,000 8,992,000 9,142,000 9,063,000 9,023,000 9,009,000 8,904,000 8,802,000 8,699,000 8,599,000 
  losses (gains) on marketable equity securities                 72,000,000                                     
  unrealized gains on marketable equity securities                  -142,000,000 -59,000,000 -66,000,000 -3,000,000 4,000,000 47,000,000                               
  gains on deconsolidation                                                    
  loss on derivative assets related to terminated acquisition                  9,000,000 12,000,000 95,000,000                                 
  cash paid for derivative assets related to terminated acquisition                  -132,000,000                                 
  contributions from noncontrolling interest owners                          31,000,000 61,000,000 43,000,000 20,000,000 16,000,000 9,000,000 80,000,000                
  1. organization and significant accounting policies                                                      
  net cash paid for acquisition                                                      
  gain on deconsolidation of grail                         -15,000,000     -453,000,000                     
  loss on continuation advances                                                      
  impairment of intangible assets                              23,000,000                     
  cash paid for continuation advances                                                      
  deconsolidation of helix and grail cash                                                      
  payments on acquisition-related contingent consideration liability                                                      
  proceeds from deconsolidation of grail                       15,000,000                             
  assets                                                      
  property and equipment                                                     
  operating lease right-of-use assets                                                      
  deferred tax assets                                                     
  total assets                                                     
  liabilities and stockholders’ equity                                                      
  operating lease liabilities                                                      
  long-term debt                                                     
  retained earnings                                                     
  total liabilities and stockholders’ equity                                                     
  proceeds from sale of grail securities                              278,000,000                     
  deconsolidation of grail cash                              -52,000,000                     
  proceeds from early exercise of equity awards from a subsidiary                                  707,000 804,000                   
  payments on acquisition related contingent consideration liability                                 -29,200,000 -1,400,000        -3,985,000     
  proceeds from issuance of debt                                2,958,000                   
  deferred income tax expense                                  36,023,000 29,710,000                   
  cost-method investment gain                                      -119,000 -2,900,000 -12,582,000             
  gain on litigation settlement                                                      
  illumina, inc.consolidated statements of cash flows —                                                      
  loss on extinguishment of debt                                      325,000 3,504,000             
  incremental tax benefit related to share-based compensation                                  18,602,000 -25,714,000 -25,227,000 -58,993,000 -4,956,000 -15,541,000 -29,717,000 -76,445,000 -23,840,000 -25,306,000 -26,805,000 -50,528,000 -29,453,000 -12,381,000 -9,566,000 -5,278,000     
  repurchase of convertible notes                                                      
  net (purchases of) sales proceeds from strategic investments                                    -3,529,000 -2,842,000     -5,000,000            
  deferred income tax (benefit) expense                                     -6,200,000                 
  (gain) impairment related to discontinued product line                                                      
  change in estimated cease-use loss                                      436,000 -5,226,000 1,480,000 699,000 1,294,000 870,000           
  accrued legal contingencies                                      4,000,000    -45,717,000 11,483,000 4,817,000 5,847,000  4,299,000 15,791,000 106,922,000     
  proceeds from issuance of convertible notes                                                    
  payments on retirement of warrants                                                      
  net sales proceeds from (purchases of) strategic investments                                       -5,026,000 -12,141,000 13,067,000             
  repurchases of convertible notes                                                     
  contingent compensation expense                                          68,000 68,000 68,000 2,417,000 4,169,000 1,358,000 1,358,000 1,393,000 2,257,000 1,084,000 44,000 2,921,000 
  cost-method investment related gain                                             -55,244,000 -6,113,000     
  unsettled short-term investments purchase                                                      
  impairments                                                     
  (purchases of) sales proceeds from strategic investments                                            -7,082,000 -4,600,000         
  change in facility exit obligation                                              2,856,000        
  long-term legal contingencies                                                      
  proceeds from (purchases of) strategic investments                                                      
  payments on current portion of long-term financing obligations                                                      
  (payments for) proceeds from warrant settlements                                                      
  proceeds from sale of strategic investment                                               3,000 9,998,000     
  payments on long-term financing obligations                                               -1,581,000       
  impairment of in-process research and development                                                    
  payments on long-term financing obligation                                                 -58,000     
  amortization of acquired intangible assets                                                  5,411,000 3,740,000 3,195,000 3,195,000 
  cease-use loss                                                  2,883,000    
  cost-method investment related (gain) loss                                                      
  recovery of previously impaired note receivable                                                      
  sales and maturities of trading securities                                                      
  payments on current portion of long-term debt                                                      
  proceeds from the exercise of warrants                                                      
  incremental tax benefit related to stock options exercised                                                   -1,258,000 -1,711,000 -9,494,000 
  other non-cash adjustments                                                   1,586,000 3,108,000 2,484,000 
  unrealized (gain) loss on foreign exchange                                                      
  cash paid in business combination milestones                                                     
  unrealized gain on foreign exchange                                                    -2,830,000 1,130,000 
  proceeds from exercises of warrants                                                      

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