HALO Stock Balance Sheets

Halozyme Therapeutics Quarterly Balance Sheets Chart

Quarterly

Annual

Goodwill

Account Receivables

Cash and Cash Eq

Account Payables

Long-Term Debt

Inventory

Halozyme Therapeutics Quarterly Balance Sheets Table

Quarterly

Annual

Unit: USD	2025-06-30	2025-03-31	2024-12-31	2024-09-30	2024-06-30	2024-03-31	2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2017-06-30	2017-03-31	2016-12-31	2016-09-30	2016-06-30	2016-03-31	2015-12-31	2015-09-30	2015-06-30	2015-03-31	2014-12-31	2014-09-30	2014-06-30	2014-03-31	2013-12-31	2013-09-30	2013-06-30	2013-03-31	2012-12-31	2012-09-30	2012-06-30	2012-03-31	2011-12-31	2011-09-30	2011-06-30	2011-03-31	2010-12-31	2010-09-30	2010-06-30	2010-03-31	2009-12-31	2009-09-30	2009-06-30	2009-03-31	2008-12-31	2008-09-30	2008-06-30	2008-03-31	2007-12-31	2007-09-30	2007-06-30	2007-03-31	2006-12-31	2006-09-30	2006-06-30	2006-03-31

assets
current assets
cash and cash equivalents	61,861,000	176,328,000	115,850,000	154,318,000	187,864,000	164,627,000	118,370,000	274,227,000	221,165,000	96,383,000	234,195,000	147,159,000	90,932,000	117,835,000	118,719,000	491,683,000	446,966,000	499,450,000	147,703,000	65,741,000	133,606,000	104,820,000	120,179,000	59,202,000	67,041,000	60,595,000	57,936,000	55,019,000	55,173,000	98,012,000	168,740,000	164,397,000	114,745,000	45,188,000	66,764,000	61,207,000	61,233,000	69,093,000	43,292,000	71,514,000	67,769,000	44,287,000	61,389,000	46,375,000	56,135,000	76,570,000	27,356,947	17,492,131	27,927,551	39,017,804	99,901,000	87,614,891	102,041,617	116,608,304	52,825,527	66,329,358	79,116,705	73,829,299	83,255,848	89,840,588	41,312,426	55,176,316	67,464,506	77,635,792	89,240,763	62,065,063	63,715,906	72,493,045	82,410,139	92,558,408	97,679,085	105,114,751	100,595,143	70,970,875	44,189,403	16,100,911,000	15,099,757,000	17,570,501
marketable securities, available-for-sale	486,316,000	571,594,000	480,224,000	511,988,000	341,166,000	298,824,000	217,630,000	209,055,000	127,110,000	179,225,000	128,599,000	118,425,000	118,428,000	668,305,000	622,203,000	324,237,000	308,343,000	264,856,000	220,310,000	280,965,000	251,840,000	263,363,000	301,083,000	178,796,000	220,424,000	268,122,000	296,590,000	309,347,000	343,721,000	335,682,000	300,474,000	152,525,000	182,788,000	133,797,000	138,217,000	159,845,000	168,757,000	169,545,000	65,047,000	52,204,000	72,946,000	84,212,000	74,234,000	88,089,000	91,513,000	87,919,000	44,145,697	47,818,851	48,082,636	48,408,220
accounts receivable, net and contract assets	316,339,000	304,621,000	308,455,000	285,743,000	214,524,000	195,902,000		217,325,000	246,179,000	194,883,000		233,302,000	189,368,000
inventories	181,505,000	164,868,000	141,860,000	131,412,000	159,312,000	168,541,000	127,601,000	128,921,000	132,406,000	107,521,000	100,123,000	103,276,000	97,615,000	47,761,000	53,908,000	55,978,000	58,554,000	58,343,000	60,747,000	57,697,000	48,271,000	41,452,000	29,359,000	36,051,000	43,900,000	31,241,000	22,625,000	18,285,000	8,404,000	4,393,000	5,146,000	9,331,000	15,172,000	14,290,000	14,623,000	12,852,000	10,755,000	10,345,000	9,489,000	11,101,000	7,723,000	7,482,000	6,406,000	6,916,000	7,114,000	6,765,000	6,169,982	3,846,290	2,466,999	2,737,387		2,186,063	1,783,894	1,496,783	567,263
prepaid expenses and other current assets	76,652,000	44,617,000	38,951,000	43,515,000	84,931,000	45,690,000	48,613,000	49,478,000	38,885,000	37,007,000	45,024,000	51,039,000	45,595,000
total current assets	1,122,673,000	1,262,028,000	1,085,340,000	1,126,976,000	987,797,000	873,584,000	746,424,000	879,006,000	765,745,000	615,019,000	739,013,000	653,201,000	541,938,000	988,689,000	926,287,000	1,017,299,000	999,750,000	941,719,000	554,764,000	498,895,000	500,358,000	467,971,000	543,436,000	342,041,000	391,706,000	409,036,000	427,849,000	429,926,000	462,032,000	484,470,000	510,372,000	353,345,000	340,834,000	222,354,000	256,532,000	272,605,000	284,344,000	297,035,000	171,772,000	153,090,000	168,442,000	153,329,000	161,321,000	158,600,000	175,623,000	190,914,000	95,195,394	102,818,028	100,420,847	111,110,478		105,618,569	119,731,075	132,565,976	63,987,497	76,968,519	88,013,451	79,192,091	89,498,434	98,430,800	49,324,302	62,677,320	74,441,743	83,405,811	93,648,975	66,180,998	74,012,788	78,229,346	86,116,203	96,620,736	101,177,058	108,075,769	102,944,110	73,294,524	45,593,550	17,332,034,000	16,453,870,000	18,581,699
property and equipment	71,520,000	72,816,000	75,035,000	74,490,000	75,000,000	78,071,000	74,944,000	74,669,000	74,559,000	77,964,000	75,570,000	36,674,000	37,091,000	8,513,000	8,794,000	9,588,000	10,132,000	10,366,000	10,593,000	10,252,000	11,169,000	11,752,000	10,855,000	15,398,000	15,079,000	14,542,000	7,465,000	6,790,000	4,789,000	4,937,000	3,520,000	3,232,000	3,330,000	3,741,000	4,264,000	4,407,000	4,682,000	4,440,000	3,943,000	2,686,000	2,594,000	2,732,000	2,951,000	3,249,000	3,343,000	3,628,000	3,421,506	4,935,928	4,576,506	3,975,052		2,363,650	2,016,809	2,152,934	1,771,048	1,274,753	1,495,639	1,741,192	1,846,899	1,960,935	2,161,549	2,486,127	2,708,016	2,703,592	2,646,666	2,745,803	2,549,925	2,523,767	2,439,765	2,251,099	2,283,316	1,916,932	1,182,661	572,026	497,770	460,834,000	369,442,000	367,142
prepaid expenses and other assets	56,371,000	55,609,000	80,596,000	80,151,000	52,481,000	17,319,000	17,816,000	18,115,000	18,409,000	25,240,000	26,301,000	25,783,000	26,283,000	41,026,000	40,482,000	33,302,000	32,691,000	30,679,000	28,274,000	31,941,000	29,240,000	28,587,000	33,373,000	27,248,000	28,122,000	20,914,000	20,693,000	19,619,000	21,152,000	19,809,000	13,879,000	12,397,000	13,656,000	16,627,000	21,248,000	6,062,000	3,632,000	22,509,000	21,534,000	9,879,000	10,266,000	9,623,000	10,143,000	8,945,000	7,966,000	8,704,000	8,425,684	9,139,014	11,111,833	10,571,334		11,353,342	10,218,468	8,910,059	8,332,242	4,297,814	4,317,105	3,382,993	3,720,896	4,891,556	4,676,229	4,320,707	1,573,777	2,942,015	2,711,585	3,072,336	2,591,149	3,715,018	1,895,820	2,252,861	2,014,680	1,830,827	1,326,775	1,295,675	428,268
goodwill	416,821,000	416,821,000	416,821,000	416,821,000	416,821,000	416,821,000	416,821,000	416,821,000	416,821,000	416,223,000	409,049,000	199,481,000	199,481,000
intangible assets	366,306,000	384,068,000	401,830,000	419,592,000	437,354,000	455,116,000	472,879,000	490,641,000	510,982,000	528,817,000	546,652,000	948,904,000	976,097,000
deferred tax assets	20,208,000	5,190,000	3,855,000			616,000	4,386,000	13,410,000	23,924,000	35,684,000	44,426,000			142,508,000	155,434,000	142,481,000
total assets	2,053,899,000	2,196,532,000	2,063,477,000	2,118,030,000	1,969,453,000	1,841,527,000	1,733,270,000	1,892,662,000	1,810,440,000	1,699,447,000	1,841,511,000	1,864,543,000	1,781,390,000	1,162,248,000	1,104,429,000	1,185,420,000	1,025,863,000	966,582,000	579,924,000	524,029,000	526,997,000	492,353,000	565,874,000	370,356,000	417,830,000	429,109,000	440,248,000	444,507,000	474,754,000	495,469,000	519,945,000	357,149,000	344,786,000	226,767,000	261,515,000	282,498,000	296,127,000	309,096,000	181,789,000	158,734,000	174,047,000	159,125,000	165,977,000	164,626,000	182,052,000	197,687,000	101,792,592	110,145,126	107,387,338	116,866,295	134,728,000	107,982,219	121,747,884	134,718,910	65,758,545	78,243,272	89,509,090	80,933,283	91,345,333	100,391,735	51,485,851	65,163,447	77,149,759	86,109,403	96,295,641	68,926,801	76,562,713	80,753,113	88,555,968	98,871,835	103,460,374	109,992,701	104,126,771	73,866,550	46,091,320	17,811,703,000	16,842,147,000	18,971,676
liabilities and stockholders’ equity
current liabilities
accounts payable	18,691,000	20,074,000	10,249,000	12,398,000	15,430,000	13,325,000	11,816,000	19,318,000	10,120,000	8,695,000	17,693,000	18,166,000	12,232,000	1,266,000	1,541,000	3,322,000	4,563,000	535,000	1,928,000	433,000	4,067,000	8,320,000	6,434,000	4,314,000	12,467,000	4,089,000	4,079,000	3,331,000	6,187,000	3,628,000	7,948,000	4,152,000	5,650,000	3,079,000	3,578,000	4,641,000	3,650,000	6,211,000	4,499,000	4,437,000	4,138,000	3,299,000	3,003,000	4,342,000	3,910,000	8,658,000	3,134,757	5,591,763	7,480,982	2,884,794		3,526,839	2,087,432	3,011,181	7,556,859	1,219,905	1,731,663	1,450,993	3,820,368	1,828,069	2,101,349	4,250,024	2,820,491	5,121,914	5,430,644	5,303,100	6,668,791	4,140,976	2,814,512	3,398,587	3,055,637	2,729,727	1,548,430	1,072,178	2,017,395	1,428,044,000	1,106,262,000	1,621,122
accrued expenses	115,591,000	130,305,000	128,851,000	96,417,000	117,930,000	118,314,000	100,678,000	95,200,000	105,431,000	79,978,000	96,516,000	74,317,000	84,101,000	19,133,000	24,441,000	18,335,000	19,274,000	16,098,000	20,483,000	25,795,000	21,258,000	26,811,000	55,649,000	45,679,000	45,561,000	43,663,000	49,529,000	43,020,000	35,030,000	31,889,000	39,601,000	32,370,000	26,934,000	24,935,000	28,821,000	25,733,000	23,851,000	21,791,000	26,792,000	18,926,000	14,821,000	12,813,000	13,961,000	15,023,000	16,455,000	12,272,000	14,920,446	20,624,501	15,289,431	9,177,574		8,041,673	7,529,322	7,184,794	5,615,574	8,864,705	9,465,723	8,238,267	8,605,569	5,052,723	4,134,661	4,084,015	6,083,854	5,749,610	4,721,593	4,473,621	3,995,897	3,705,304	3,338,896	2,942,071	2,502,259	1,976,594	1,454,459	1,187,146	1,011,153	1,206,630,000	928,258,000	818,007
total current liabilities	134,282,000	150,379,000	139,100,000	108,815,000	133,360,000	131,639,000	112,494,000	115,185,000	116,393,000	91,919,000	130,789,000	109,384,000	199,512,000	111,691,000	117,147,000	113,153,000	114,251,000	107,421,000	421,385,000	26,976,000	26,073,000	42,002,000	85,637,000	108,041,000	135,417,000	138,662,000	149,361,000	139,119,000	132,429,000	119,224,000	131,328,000	102,048,000	82,615,000	61,708,000	54,585,000	52,660,000	38,885,000	64,223,000	62,457,000	44,851,000	35,039,000	26,209,000	24,331,000	34,593,000	31,721,000	36,360,000	25,453,032	39,623,816	32,833,250	19,750,581		21,038,759	16,147,588	16,680,775	17,301,840	13,792,405	31,543,057	12,603,739	15,343,066	11,781,294	11,061,745	13,760,587	14,396,949	15,813,104	15,168,415	13,330,451	14,218,418	11,062,360	9,408,869	9,602,641	8,864,121	8,261,024	6,001,356	5,156,256	4,250,540	2,757,039,000	2,425,789,000	2,693,267
long-term debt	1,509,100,000	1,507,447,000	1,505,798,000	1,504,154,000	1,502,515,000	1,500,879,000	1,499,248,000	1,497,621,000	1,495,998,000	1,494,380,000	1,492,766,000	1,491,156,000	1,147,129,000	788,099,000	787,255,000	786,454,000	785,571,000	784,731,000		393,631,000	390,079,000	386,571,000	383,045,000	9,308,000	14,083,000	18,742,000	34,874,000	57,940,000	79,080,000	102,696,000	125,140,000	145,417,000	165,517,000	184,430,000	199,228,000	199,803,000	204,850,000	168,600,000	27,971,000	34,094,000	40,098,000	45,985,000	49,860,000	39,762,000	43,613,000	47,389,000	49,771,737	23,781,955	26,075,507	28,323,233	29,662,000
other long-term liabilities	77,769,000	56,436,000	54,758,000	40,406,000	30,507,000	31,201,000	37,720,000	28,422,000	30,875,000	29,573,000	30,433,000	5,418,000	5,551,000	171,000	544,000	1,609,000	2,267,000	2,809,000	3,466,000	3,793,000	4,627,000	5,097,000	4,180,000	6,407,000	6,532,000	7,149,000	2,118,000	2,203,000	2,314,000	2,479,000	814,000	540,000	710,000	326,000	358,000	1,178,000	600,000	3,906,000	4,443,000	3,746,000	3,429,000	3,127,000	3,167,000	2,759,000	2,854,000	2,343,000
total liabilities	1,721,151,000	1,714,262,000	1,699,656,000	1,665,327,000	1,680,029,000	1,663,719,000	1,649,462,000	1,643,481,000	1,659,407,000	1,633,597,000																																									85,875,000
commitments and contingencies
stockholders’ equity																																																			48,854,000
preferred stock - 0.001 par value; 20,000 shares authorized; no shares issued and outstanding
common stock - 0.001 par value; 300,000 shares authorized; 117,621 and 123,138 shares issued and outstanding as of june 30, 2025 and december 31, 2024, respectively	118,000
additional paid-in capital		7,596,000		61,886,000	30,747,000	11,794,000	2,409,000	25,537,000	12,068,000		27,368,000	13,177,000	271,169,000	261,713,000	256,347,000	407,229,000	461,897,000	501,186,000	625,483,000	646,184,000	688,318,000	667,677,000	695,066,000	814,095,000	803,782,000	789,483,000	780,457,000	769,382,000	756,978,000	744,359,000	731,044,000	718,553,000	707,086,000	559,659,000	552,737,000	545,751,000	538,585,000	531,390,000	525,628,000	518,647,000	512,657,000	502,980,000	491,694,000	485,014,000	480,044,000	475,249,000	361,929,935	356,449,825	351,843,228	349,459,065		345,244,876	343,283,575	341,088,827	255,817,772	253,557,547	251,721,011	248,300,828	245,502,670	243,261,452	181,739,270	180,513,941	178,821,852	175,854,683	171,779,912	132,216,125	128,948,064	127,628,664	125,525,748	124,140,964	122,685,443	121,122,922	119,937,129
accumulated other comprehensive income	-28,403,000	-3,413,000	3,829,000							24,000					-620,000	-14,000	-24,000	-9,000		426,000	1,086,000	11,000		392,000	390,000	61,000										83,000	216,000	88,000					-41,000	-46,000	3,000	-25,000	17,054	15,779
retained earnings	361,033,000	477,964,000	359,869,000	397,629,000	260,618,000	167,373,000	90,550,000	222,285,000	140,448,000	65,694,000	143,217,000	85,515,000	23,881,000
total stockholders’ equity	332,748,000	482,270,000	363,821,000	452,703,000	289,424,000	177,808,000	83,808,000	249,181,000	151,033,000	65,850,000	169,798,000	96,991,000	293,171,000	260,256,000	196,953,000	281,674,000	119,748,000	67,595,000	151,047,000	98,988,000	105,577,000	58,042,000	91,765,000	245,353,000	260,052,000	260,047,000	248,887,000	239,738,000	254,925,000	265,064,000	208,366,000	72,389,000	58,165,000				9,920,000	29,472,000	42,999,000	31,799,000	50,229,000	37,545,000	41,352,000	39,940,000	55,299,000	66,748,000			11,143,677	31,681,060		51,189,777	69,234,318	81,060,411	10,900,116	27,055,163	20,053,396	13,515,349	20,351,456	35,003,715			6,903,389	16,600,485	26,434,558	3,924,086	15,379,996	30,885,809	39,654,037	49,271,052	57,767,924	64,912,893	70,755,192	40,903,649	23,081,235	15,054,664,000	14,416,358,000	16,278,409
total liabilities and stockholders’ equity	2,053,899,000	2,196,532,000	2,063,477,000	2,118,030,000	1,969,453,000	1,841,527,000	1,733,270,000	1,892,662,000	1,810,440,000	1,699,447,000	1,841,511,000	1,864,543,000	1,781,390,000	1,162,248,000	1,104,429,000	1,185,420,000	1,025,863,000	966,582,000	579,924,000	524,029,000	526,997,000	492,353,000	565,874,000	370,356,000	417,830,000	429,109,000	440,248,000	444,507,000	474,754,000	495,469,000	519,945,000	357,149,000	344,786,000				296,127,000	309,096,000	181,789,000	158,734,000	174,047,000	159,125,000	165,977,000	164,626,000	182,052,000	197,687,000			107,387,338	116,866,295		107,982,219	121,747,884	134,718,910	65,758,545	78,243,272	89,509,090	80,933,283	91,345,333	100,391,735			77,149,759	86,109,403	96,295,641	68,926,801	76,562,713	80,753,113	88,555,968	98,871,835	103,460,374	109,992,701	104,126,771	73,866,550	46,091,320	17,811,703,000	16,842,147,000	18,971,676
common stock - 0.001 par value; 300,000 shares authorized; 123,170 and 123,138 shares issued and outstanding as of march 31, 2025 and december 31, 2024, respectively		123,000
common stock - 0.001 par value; 300,000 shares authorized; 123,138 and 126,770 shares issued and outstanding as of december 31, 2024 and 2023, respectively			123,000
deferred tax liabilities				11,952,000	13,647,000							28,989,000	3,288,000
common stock - 0.001 par value; 300,000 shares authorized; 127,183 and 126,770 shares issued and outstanding as of september 30, 2024 and december 31, 2023, respectively				127,000
accumulated other comprehensive loss				-6,939,000	-2,068,000	-1,486,000	-9,278,000		-1,615,000		-922,000	-1,836,000	-2,017,000	-2,791,000					22,000				240,000				-277,000	-478,000	-736,000	-870,000	-450,000	-53,000	-61,000	-49,000	-6,000				-99,000		-40,000	-27,000							-39,309	-29,131
common stock - 0.001 par value; 300,000 shares authorized; 126,535 and 126,770 shares issued and outstanding as of june 30, 2024 and december 31, 2023, respectively					127,000
common stock - 0.001 par value; 300,000 shares authorized; 127,186 and 126,770 shares issued and outstanding as of march 31, 2024 and december 31, 2023, respectively						127,000
accounts receivable, net and other contract assets							234,210,000				231,072,000				90,975,000	112,099,000	153,196,000	88,391,000	97,730,000	62,551,000					32,219,000			27,656,000	33,582,000
restricted cash										500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000	500,000
current portion of long-term debt											13,334,000	13,315,000	99,048,000	89,546,000	89,419,000	89,251,000	89,167,000	89,042,000	397,228,000			2,859,000	19,542,000	54,537,000	70,878,000	86,663,000	91,506,000	88,521,000	86,965,000	82,460,000	77,211,000	61,433,000	45,515,000	29,601,000	17,393,000	12,394,000	3,288,000	27,417,000	21,862,000	15,699,000	9,656,000	3,730,000		10,075,000	6,203,000	2,404,000		5,970,119	3,643,156	1,362,055
contingent liability									13,888,000	15,472,000	15,472,000	129,772,000	130,000,000
common stock - 0.001 par value; 300,000 shares authorized; 126,770 and 135,154 shares issued and outstanding as of december 31, 2023 and 2022, respectively							127,000
deferred revenue, current portion								667,000	842,000	3,246,000	3,246,000	3,586,000	4,131,000	1,746,000	1,746,000	2,245,000	1,247,000	1,746,000	1,746,000	748,000	748,000	4,012,000	4,012,000	3,511,000	6,511,000	4,247,000	4,247,000	4,247,000	4,247,000	1,247,000	6,568,000	4,093,000	4,516,000	4,093,000	4,793,000	9,892,000	8,096,000	8,804,000	9,304,000	5,789,000	6,424,000	6,367,000	7,367,000	5,153,000	5,153,000	13,026,000	7,397,829	7,437,433	6,419,681	6,326,158		9,470,247	6,530,834	6,484,800	4,129,407
deferred revenue, net of current portion								2,253,000	2,253,000	2,253,000	2,253,000	2,833,000	2,739,000	2,031,000	2,530,000	2,530,000	4,026,000	4,026,000	4,026,000	641,000	641,000	641,000	1,247,000	1,247,000	1,746,000	4,509,000	5,008,000	5,507,000	6,006,000	6,006,000	54,297,000	36,755,000	37,779,000	38,802,000	39,825,000	40,849,000	41,872,000	42,895,000	43,919,000	44,244,000	45,252,000	46,259,000	47,267,000	47,572,000	48,565,000	44,847,000	45,745,449	45,940,511	33,681,996	34,318,481		34,883,135	35,506,951	36,130,767	36,754,583	36,667,445	37,279,394	54,447,803	55,176,422	53,024,341	53,857,056	53,830,590	54,989,588	52,747,933	53,667,269	50,628,280	45,894,726	37,731,528	38,376,170	38,992,374	35,963,266	36,287,055	27,370,223	27,806,645	18,759,545
common stock - 0.001 par value; 300,000 shares authorized; 132,081 and 135,154 shares issued and outstanding as of september 30, 2023 and december 31, 2022, respectively								132,000
accumulated other comprehensive gain								1,227,000
common stock - 0.001 par value; 300,000 shares authorized; 131,856 and 135,154 shares issued and outstanding as of june 30, 2023 and december 31, 2022, respectively									132,000
common stock - 0.001 par value; 300,000 shares authorized; 131,662 and 135,154 shares issued and outstanding as of march 31, 2023 and december 31, 2022, respectively										132,000
current assets:
current liabilities:
stockholders’ equity:
common stock - 0.001 par value; 300,000 shares authorized; 135,154 and 137,498 shares issued and outstanding at december 31, 2022 and 2021, respectively											135,000
common stock - 0.001 par value; 300,000 shares authorized; 135,211 and 137,498 shares issued and outstanding as of september 30, 2022 and december 31, 2021, respectively												135,000
common stock - 0.001 par value; 300,000 shares authorized; 137,681 and 137,498 shares issued and outstanding at june 30, 2022 and december 31, 2021, respectively													138,000
accounts receivable														113,762,000							37,401,000	29,749,000	59,442,000	40,744,000		28,164,000	30,005,000			26,574,000	22,133,000	14,695,000	14,473,000	12,452,000	15,680,000	17,679,000	23,227,000	25,543,000	32,410,000	8,392,000	9,738,000	7,725,000	9,149,000	8,275,000	12,895,000	10,956,000	9,097,084	24,521,742	10,831,828	10,375,733		4,464,273	5,687,096	5,550,830	2,262,465	6,237,904	4,495,792	1,731,325	2,328,268	2,622,076	2,253,771	2,020,746	4,243,909	1,589,750	893,093	476,837	7,264,410	1,495,855	1,160,990	1,130,384	779,825	416,888	401,932	552,789	533,387
common stock - 0.001 par value; 300,000 shares authorized; 137,888 and 137,498 shares issued and outstanding at march 31, 2022 and december 31, 2021, respectively														138,000
accumulated income														1,196,000
common stock - 0.001 par value; 300,000 shares authorized; 137,498 and 135,030 shares issued and outstanding at december 31, 2021 and 2020, respectively															138,000
accumulated deficit															-58,912,000	-125,682,000	-342,267,000	-433,725,000	-474,593,000	-547,757,000	-583,964,000	-609,781,000	-603,678,000	-569,281,000	-544,266,000	-529,642,000	-531,438,000	-529,311,000	-501,461,000	-478,569,000	-522,371,000	-646,253,000	-649,002,000	-618,239,000	-585,342,000	-557,955,000	-529,010,000	-502,135,000	-482,658,000	-486,976,000	-462,516,000	-465,535,000	-450,427,000	-445,153,000	-424,873,000	-408,600,000	-382,052,199	-360,065,896	-340,773,528	-317,862,017		-294,167,792	-274,161,946	-260,140,827	-245,021,646	-226,606,032	-231,771,225	-234,887,512	-225,251,795	-208,358,121	-195,948,545	-183,797,622	-172,010,145	-159,345,293	-145,435,011	-128,374,986	-113,649,622	-96,823,968	-85,951,810	-74,949,420	-64,995,423	-56,287,032	-49,258,251	-44,456,544	-41,099,240	-36,721,277,000	-33,070,239,000	-29,837,448
common stock - 0.001 par value; 300,000 shares authorized; 140,966 and 135,030 shares issued and outstanding at september 30, 2021 and december 31, 2020, respectively																141,000
common stock - 0.001 par value; 300,000 shares authorized; 142,181 and 135,030 shares issued and outstanding at june 30, 2021 and december 31, 2020, respectively																	142,000
common stock - 0.001 par value; 300,000 shares authorized; 143,380 and 135,030 shares issued and outstanding at march 31, 2021 and december 31, 2020, respectively																		143,000
common stock - 0.001 par value; 300,000 shares authorized; 135,030 and 136,713 shares issued and outstanding at december 31, 2020 and 2019, respectively																			135,000
common stock - 0.001 par value; 300,000 shares authorized; 135,369 and 136,713 shares issued and outstanding at september 30, 2020 and december 31, 2019, respectively																				135,000
common stock - 0.001 par value; 300,000 shares authorized; 136,671 and 136,713 shares issued and outstanding at june 30, 2020 and december 31, 2019, respectively																					137,000
common stock - 0.001 par value; 300,000 shares authorized; 135,364 and 136,713 shares issued and outstanding at march 31, 2020 and december 31, 2019, respectively																						135,000
common stock - 0.001 par value; 300,000 shares authorized; 136,713 and 144,725 shares issued and outstanding at december 31, 2019 and 2018, respectively																							137,000
common stock - 0.001 par value; 300,000 shares authorized; 146,457 and 144,725 shares issued and outstanding at september 30, 2019 and december 31, 2018, respectively																								147,000
common stock - 0.001 par value; 300,000 shares authorized; 145,859 and 144,725 shares issued and outstanding at june 30, 2019 and december 31, 2018, respectively																									146,000
common stock - 0.001 par value; 200,000 shares authorized;145,364 and 144,725 shares issued and outstanding at march 31, 2019 and december 31, 2018, respectively																										145,000
common stock - 0.001 par value; 200,000 shares authorized; 144,725 and 142,789 shares issued and outstanding at december 31, 2018 and 2017, respectively																											145,000
common stock - 0.001 par value; 200,000 shares authorized; 144,522 and 142,789 shares issued and outstanding at september 30, 2018 and december 31, 2017, respectively																												145,000
common stock - 0.001 par value; 200,000 shares authorized; 144,222 and 142,789 shares issued and outstanding at june 30, 2018 and december 31, 2017, respectively																													144,000
common stock - 0.001 par value; 200,000 shares authorized; 143,886 and 142,789 shares issued and outstanding at march 31, 2018 and december 31, 2017, respectively																														144,000
common stock - 0.001 par value; 200,000 shares authorized; 142,789 and 129,502 shares issued and outstanding at december 31, 2017 and 2016, respectively																															143,000
common stock - 0.001 par value; 200,000 shares authorized; 142,301 and 129,502 shares issued and outstanding at september 30, 2017 and december 31, 2016, respectively																																142,000
common stock - 0.001 par value; 200,000 shares authorized; 141,908 and 129,502 shares issued and outstanding at june 30, 2017 and december 31, 2016, respectively																																	142,000
liabilities and stockholders’ deficit
stockholders’ deficit:
common stock - 0.001 par value; 200,000 shares authorized; 129,822 and 129,502 shares issued and outstanding at march 31, 2017 and december 31, 2016, respectively																																		130,000
total stockholders’ deficit																																		-58,499,000
total liabilities and stockholders’ deficit																																		226,767,000
revenues:
product sales																																		11,434,000
royalties																																		13,982,000
revenues under collaborative agreements																																		4,152,000
total revenues																																		29,568,000
operating expenses:
cost of product sales																																		7,544,000
research and development																																		36,935,000
selling, general and administrative																																		12,615,000
total operating expenses																																		57,094,000
operating income																																		-27,526,000
other income:
investment and other income																																		287,000
interest expense																																		-5,448,000
net income before income taxes																																		-32,687,000
income tax expense																																		210,000
net income																																		-32,897,000
net income per share
basic and diluted																																		-260
shares used in computing net income per share:
liabilities and stockholders’ (deficit) equity
stockholders’ (deficit) equity:
preferred stock — 0.001 par value; 20,000 shares authorized; no shares issued and outstanding
common stock — 0.001 par value; 200,000 shares authorized; 129,502 and 128,152 shares issued and outstanding at december 31, 2016 and 2015, respectively																																			130,000
total stockholders’ (deficit) equity																																			-32,481,000	-11,992,000											-19,990,676	-3,486,305													-14,117,265	-3,191,799
total liabilities and stockholders’ (deficit) equity																																			261,515,000	282,498,000											101,792,592	110,145,126													51,485,851	65,163,447
prepaid manufacturing costs																																				14,960,000	16,740,000
common stock - 0.001 par value; 200,000 shares authorized; 129,488 and 128,152 shares issued and outstanding at september 30, 2016 and december 31, 2015, respectively																																				129,000
common stock - 0.001 par value; 200,000 shares authorized; 129,411 and 128,152 shares issued and outstanding at june 30, 2016 and december 31, 2015, respectively																																					129,000
common stock - 0.001 par value; 200,000 shares authorized; 129,114 and 128,152 shares issued and outstanding at march 31, 2016 and december 31, 2015, respectively																																						129,000
common stock — 0.001 par value; 200,000 shares authorized; 128,152 and 125,721 shares issued and outstanding at december 31, 2015 and 2014, respectively																																							128,000
common stock - 0.001 par value; 200,000 shares authorized; 127,811 and 125,721 shares issued and outstanding at september 30, 2015 and december 31, 2014, respectively																																								128,000
common stock - 0.001 par value; 200,000 shares authorized; 127,764 and 125,721 shares issued and outstanding at june 30, 2015 and december 31, 2014, respectively																																									128,000
common stock - 0.001 par value; 200,000 shares authorized; 127,163 and 125,721 shares issued and outstanding at march 31, 2015 and december 31, 2014, respectively																																										127,000
common stock — 0.001 par value; 200,000 shares authorized; 125,721 and 114,534 shares issued and outstanding at december 31, 2014 and 2013, respectively																																											126,000
common stock - 0.001 par value; 200,000 shares authorized; 125,546 and 114,533 shares issued and outstanding at september 30, 2014 and december 31, 2013, respectively																																												125,000
common stock - 0.001 par value; 200,000 shares authorized; 125,294 and 114,533 shares issued and outstanding at june 30, 2014 and december 31, 2013, respectively																																													125,000
common stock - 0.001 par value; 200,000 shares authorized; 124,483 and 114,533 shares issued and outstanding at march 31, 2014 and december 31, 2013, respectively																																														124,000
lease financing obligation																																																2,550,000	2,100,000	1,450,000
deferred rent, net of current portion																																															794,782	813,689	874,208	906,091		870,548	859,027	846,957	802,006	728,259	633,243	366,392	474,389	582,385	684,315	764,069	859,833	947,881	1,025,399	1,043,984	1,069,573	1,073,416	1,116,892	1,005,768	865,063	531,729
other long-term liability																																															18,268	921,460	678,700	436,849
preferred stock — 0.001 par value; 20,000,000 shares authorized; no shares issued and outstanding
common stock — 0.001 par value; 200,000,000 shares authorized; 114,533,466 shares issued and outstanding at december 31, 2013 and 150,000,000 shares authorized; 112,709,174 shares issued and outstanding at december 31, 2012																																															114,534
preferred stock - 0.001 par value; 20,000,000 shares authorized; no shares issued and outstanding
common stock - 0.001 par value; 200,000,000 shares authorized; 113,986,739 shares issued and outstanding at september 30, 2013 and 150,000,000 shares authorized; 112,709,174 shares issued and outstanding at december 31, 2012																																																113,987
common stock - 0.001 par value; 200,000,000 shares authorized; 113,285,582 shares issued and outstanding at june 30, 2013 and 150,000,000 shares authorized; 112,709,174 shares issued and outstanding at december 31, 2012																																																	113,286
common stock - 0.001 par value; 150,000,000 shares authorized; 113,142,900 and 112,709,174 shares issued and outstanding at march 31, 2013 and december 31, 2012, respectively																																																		113,143
working capital																																																			112,082,000
deferred revenue																																																			43,846,000					3,707,795	20,345,671	2,914,479	2,917,129	4,900,502	4,825,735	5,426,548	5,492,604	4,941,580	5,016,178	3,553,730	3,553,730	3,216,080	3,255,461	3,261,983	3,306,225	3,554,703	2,998,467	2,896,932	1,221,992	122,365,000	391,269,000	254,138
common stock - 0.001 par value; 150,000,000 shares authorized; 112,692,527 and 103,989,272 shares issued and outstanding at september 30, 2012 and december 31, 2011, respectively																																																				112,693
preferred stock – 0.001 par value; 20,000,000 shares authorized; no shares issued and outstanding
common stock – 0.001 par value; 150,000,000 shares authorized; 112,688,597 and 103,989,272 shares issued and outstanding at june 30, 2012 and december 31, 2011, respectively																																																					112,689
common stock — 0.001 par value; 150,000,000 shares authorized; 112,411,014 and 103,989,272 shares issued and outstanding at march 31, 2012 and december 31, 2011, respectively																																																						112,411
common stock — 0.001 par value; 150,000,000 shares authorized; 103,989,272 and 100,580,849 shares issued and outstanding at december 31, 2011 and 2010, respectively																																																							103,990
inventory																																																								103,443	83,849	248,474	193,422	1,076,580	1,081,876	1,159,551	1,159,551	1,238,254	803,534	566,762	441,323	525,428	649,254	679,083	703,468	713,303	620,260	475,185	442,492	233,767,000	414,059,000	286,189
common stock — 0.001 par value; 150,000,000 shares authorized; 103,647,930 and 100,580,849 shares issued and outstanding at september 30, 2011 and december 31, 2010, respectively																																																								103,648
common stock — 0.001 par value; 150,000,000 shares authorized; 103,609,419 and 100,580,849 shares issued and outstanding at june 30, 2011 and december 31, 2010, respectively																																																									103,610
common stock — 0.001 par value; 150,000,000 shares authorized; 102,033,491 and 100,580,849 shares issued and outstanding at march 31, 2011 and december 31, 2010, respectively																																																										102,033
common stock — 0.001 par value; 150,000,000 shares authorized; 100,580,849 and 91,681,756 shares issued and outstanding at december 31, 2010 and 2009, respectively																																																											100,581
common stock - 0.001 par value; 150,000,000 shares authorized; 100,383,410 and 91,681,756 shares issued and outstanding at september 30, 2010 and december 31, 2009, respectively																																																												100,384
common stock — 0.001 par value; 150,000,000 shares authorized; 92,010,298 and 91,681,756 shares issued and outstanding at june 30, 2010 and december 31, 2009, respectively																																																													92,010
common stock — 0.001 par value; 150,000,000 shares authorized; 91,881,570 and 91,681,756 shares issued and outstanding at march 31, 2010 and december 31, 2009, respectively																																																														91,882
common stock — 0.001 par value; 150,000,000 shares authorized; 91,681,756 and 81,553,654 shares issued and outstanding at december 31, 2009 and 2008, respectively																																																															91,682
common stock - 0.001 par value; 150,000,000 shares authorized; 91,095,288 and 81,553,654 shares issued and outstanding at september 30, 2009 and december 31, 2008, respectively																																																																91,095
common stock — 0.001 par value; 150,000,000 shares authorized; 89,656,578 and 81,553,654 shares issued and outstanding at june 30, 2009 and december 31, 2008, respectively																																																																	89,657
common stock — 0.001 par value; 150,000,000 shares authorized; 82,946,637 and 81,553,654 shares issued and outstanding at march 31, 2009 and december 31, 2008, respectively																																																																		82,947
common stock — 0.001 par value; 150,000,000 shares authorized; 81,553,654 and 77,903,944 shares issued and outstanding at december 31, 2008 and 2007, respectively																																																																			81,554
common stock — 0.001 par value; 150,000,000 shares authorized; 81,112,726 and 77,903,944 shares issued and outstanding at september 30, 2008 and december 31, 2007, respectively																																																																				81,113
common stock — 0.001 par value; 150,000,000 shares authorized; 80,098,622 and 77,903,944 shares issued and outstanding at june 30, 2008 and december 31, 2007, respectively																																																																					80,099
common stock — 0.001 par value; 150,000,000 shares authorized; 79,507,955 and 77,903,944 shares issued and outstanding at march 31, 2008 and december 31, 2007, respectively																																																																						79,508
common stock — 0.001 par value; 150,000,000 shares authorized; 77,903,944 and 68,736,993 shares issued and outstanding as of december 31, 2007 and 2006, respectively																																																																							77,904
common stock — 0.001 par value; 150,000,000 shares authorized; 77,002,780 and 68,736,993 shares issued and outstanding at september 30, 2007 and december 31, 2006, respectively																																																																								77,003
preferred stock — .001 par value; 500,000 shares authorized; no shares issued and outstanding
common stock — .001 par value; 150,000,000 shares authorized; 76,314,190 and 68,736,993 shares issued and outstanding at june 30, 2007 and december 31, 2006, respectively																																																																									76,314
preferred stock, 0.001 par value; 500,000 shares authorized; none issued and outstanding
common stock																																																																										71,531	68,737	64,449,000	62,052,000	61,348
additional paid-in-capital																																																																										85,288,662	64,111,738	51,711,492,000	47,424,545,000	46,054,509
other assets																																																																												18,835,000	18,835,000	22,835
receivables																																																																												384,206,000	400,652,000	119,686
prepaid expenses																																																																												613,150,000	539,402,000	605,323

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