Quarterly
Annual
| Unit: USD | 2025-12-31 | 2025-10-03 | 2025-07-04 | 2025-04-04 | 2025-01-03 | 2024-09-30 | 2024-09-27 | 2024-06-30 | 2024-06-28 | 2024-03-31 | 2024-03-29 | 2023-12-31 | 2023-12-29 | 2023-09-30 | 2023-09-29 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-12-30 | 2022-09-30 | 2022-07-01 | 2022-06-30 | 2022-04-01 | 2022-03-31 | 2021-12-31 | 2021-10-01 | 2021-09-30 | 2021-07-02 | 2021-06-30 | 2021-04-02 | 2021-03-31 | 2021-01-01 | 2020-12-31 | 2020-10-02 | 2020-09-30 | 2020-07-03 | 2020-06-30 | 2020-04-03 | 2020-03-31 | 2019-09-30 | 2019-09-27 | 2019-06-30 | 2019-06-28 | 2019-03-31 | 2019-03-29 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | 2017-12-31 | 2017-09-30 | 2017-06-30 | 2017-03-31 | 2016-12-31 | 2016-09-30 | 2016-06-30 | 2016-03-31 | 2015-09-30 | 2015-07-03 | 2015-06-30 | 2015-04-03 | 2015-03-31 | 2014-12-31 | 2014-09-30 | 2014-09-26 | 2014-06-30 | 2014-06-27 | 2014-03-31 | 2014-03-28 | 2013-12-31 | 2013-09-30 | 2013-06-30 | 2013-03-31 | 2012-12-31 | 2012-09-30 | 2012-06-30 | 2012-03-31 | 2011-12-31 | 2011-09-30 | 2011-06-30 | 2011-03-31 | 2010-12-31 | 2010-09-30 | 2010-06-30 | 2010-03-31 | 2009-12-31 | 2009-09-30 | 2009-06-30 | 2009-03-31 | 2008-09-30 | 2008-06-30 | 2008-03-31 | 2007-12-31 | 2007-09-30 | 2007-06-30 | 2007-03-31 | 2006-12-31 | 2006-09-30 | 2006-06-30 | 2006-03-31 | 2005-12-31 | 2005-09-30 | 2005-06-30 | 2005-03-31 | 2004-12-31 | 2004-09-30 | 2004-06-30 | 2004-03-31 | 2003-09-30 | 2003-06-30 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
revenues: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
net product revenues | 233,168,000 | 542,930,000 | 520,014,000 | 513,283,000 | 515,232,000 | 478,059,000 | 478,059,000 | 437,581,000 | 437,581,000 | 378,523,000 | 378,523,000 | 429,336,000 | 426,497,000 | 426,497,000 | 409,646,000 | 363,400,000 | 377,419,000 | 366,482,000 | 347,044,000 | 347,044,000 | 310,298,000 | 310,298,000 | 302,679,000 | 263,117,000 | 263,117,000 | 284,248,000 | 284,248,000 | 227,212,000 | 227,212,000 | 218,753,000 | 168,587,000 | 168,587,000 | 178,730,000 | 178,730,000 | 193,880,000 | 193,880,000 | 191,768,000 | 191,768,000 | 193,675,000 | 193,675,000 | 179,581,000 | 179,581,000 | 176,225,000 | 162,946,000 | 145,836,000 | 134,272,000 | 95,711,000 | 96,416,000 | 88,004,000 | 68,877,000 | 51,916,000 | 42,742,000 | 31,618,000 | 9,099,000 | 6,854,000 | 7,992,000 | 7,992,000 | 9,388,000 | 9,388,000 | 7,353,000 | 6,291,000 | 6,291,000 | 6,562,000 | 6,562,000 | 4,905,000 | 4,905,000 | 4,347,000 | 4,771,000 | 4,043,000 | 1,856,000 | ||||||||||||||||||||||||||||||||||||||||
collaboration revenues | 36,309,000 | 54,825,000 | 48,247,000 | 42,164,000 | 45,542,500 | 62,451,000 | 40,272,000 | 78,074,000 | 24,361,000 | 56,094,000 | 11,004,000 | 12,010,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
total revenues | 447,238,000 | 597,755,000 | 568,261,000 | 555,447,000 | 566,755,000 | 539,542,000 | 539,542,000 | 637,178,000 | 637,178,000 | 425,226,000 | 425,226,000 | 479,652,000 | 471,920,000 | 471,920,000 | 469,848,000 | 408,788,000 | 423,917,000 | 411,738,000 | 419,427,000 | 419,427,000 | 355,980,000 | 355,980,000 | 451,140,000 | 328,423,000 | 328,423,000 | 385,177,000 | 385,177,000 | 270,230,000 | 270,230,000 | 250,289,000 | 231,092,000 | 231,092,000 | 259,479,000 | 259,479,000 | 226,915,000 | 226,915,000 | 271,703,000 | 271,703,000 | 240,275,000 | 240,275,000 | 215,487,000 | 215,487,000 | 228,602,000 | 225,397,000 | 186,108,000 | 212,346,000 | 120,072,000 | 152,510,000 | 99,008,000 | 80,887,000 | 77,581,000 | 62,194,000 | 36,252,000 | 15,427,000 | 9,854,000 | 7,353,000 | 6,291,000 | 6,291,000 | 6,562,000 | 6,562,000 | 4,905,000 | 4,905,000 | 4,347,000 | 5,466,000 | 11,856,000 | 9,669,000 | 7,814,000 | 13,313,000 | 7,813,000 | 18,510,000 | 93,308,000 | 128,272,000 | 32,162,000 | 35,893,000 | 7,490,000 | 54,474,000 | 47,596,000 | 42,199,000 | 10,178,000 | 54,976,000 | 27,402,000 | 25,302,000 | 29,932,000 | 30,412,000 | 27,944,000 | 29,250,000 | 26,825,000 | 29,259,000 | 28,136,000 | 29,771,000 | 23,540,000 | 27,240,000 | 18,119,000 | 14,377,000 | 14,400,000 | 34,310,000 | 12,874,000 | 15,744,000 | 12,662,000 | 12,559,000 | 11,892,000 | 12,439,000 | 13,005,000 | |||||||
yoy | -21.09% | 10.79% | 5.32% | -12.83% | -11.05% | 26.88% | 26.88% | 32.84% | -9.89% | -9.89% | 17.34% | 11.32% | 14.11% | -2.54% | 19.08% | 15.66% | -7.03% | 27.71% | 8.39% | -7.58% | 17.13% | 21.53% | 21.53% | 53.89% | 16.94% | 16.94% | -3.54% | 1.84% | 1.84% | -4.50% | -4.50% | -5.56% | -5.56% | 26.09% | 26.09% | 5.11% | 6.60% | 15.79% | 1.48% | 90.39% | 47.79% | 87.97% | 162.52% | 54.77% | 145.22% | 173.11% | 424.32% | 687.30% | 12.05% | 28.26% | 28.26% | 50.95% | 20.05% | -58.63% | -49.27% | -44.37% | -58.94% | 51.75% | -47.76% | -91.63% | -89.62% | -75.71% | -48.43% | 1145.77% | 135.47% | -32.43% | -14.94% | -26.41% | -0.91% | 73.70% | 66.78% | -66.00% | 80.77% | -1.94% | -13.50% | 11.58% | 3.94% | -0.68% | -1.75% | 13.95% | 7.41% | 55.28% | 107.07% | 63.47% | -20.61% | 40.74% | -8.68% | 13.73% | 173.19% | 8.26% | 26.57% | -2.64% | ||||||||||||||||||
qoq | -25.18% | 5.19% | 2.31% | -2.00% | 5.04% | 0.00% | -15.32% | 0.00% | 49.84% | 0.00% | 1.64% | 0.00% | 0.44% | 14.94% | 2.96% | -1.83% | 0.00% | 17.82% | 0.00% | -21.09% | 37.37% | 0.00% | -14.73% | 0.00% | 42.54% | 0.00% | 8.31% | 0.00% | -10.94% | 0.00% | 14.35% | 0.00% | -16.48% | 0.00% | 13.08% | 0.00% | 11.50% | 0.00% | -5.74% | 1.42% | 21.11% | -12.36% | 76.85% | -21.27% | 54.04% | 22.40% | 4.26% | 24.74% | 71.56% | 134.99% | 56.56% | 16.88% | 0.00% | -4.13% | 0.00% | 33.78% | 0.00% | 12.84% | -20.47% | -53.90% | 22.62% | 23.74% | -41.31% | 70.40% | -57.79% | -80.16% | -27.26% | 298.83% | -10.39% | 379.21% | -86.25% | 14.45% | 12.79% | 314.61% | -81.49% | 100.63% | 8.30% | -15.47% | -1.58% | 8.83% | -4.46% | 9.04% | -8.32% | 3.99% | -5.49% | 26.47% | -13.58% | 50.34% | 26.03% | -0.16% | -58.03% | 166.51% | -18.23% | 24.34% | 0.82% | 5.61% | -4.40% | -4.35% | ||||||||||||
operating expenses: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cost of goods sold | 19,000,000 | 18,574,000 | 19,470,000 | 19,172,000 | 19,965,000 | 17,328,000 | 17,328,000 | 17,667,000 | 17,667,000 | 21,256,000 | 21,256,000 | 21,753,000 | 18,774,000 | 18,774,000 | 17,705,000 | 14,315,000 | 15,920,000 | 15,305,000 | 13,481,000 | 13,481,000 | 13,203,000 | 13,203,000 | 12,917,000 | 11,874,000 | 11,874,000 | 14,884,000 | 14,884,000 | 13,198,000 | 13,198,000 | 5,862,000 | 8,725,000 | 8,725,000 | 9,221,000 | 9,221,000 | 9,289,000 | 9,289,000 | 7,537,000 | 7,537,000 | 7,539,000 | 7,539,000 | 7,501,000 | 7,501,000 | 7,352,000 | 7,360,000 | 5,997,000 | 5,639,000 | 4,191,000 | 4,658,000 | 3,014,000 | 3,203,000 | 1,852,000 | 2,455,000 | 1,560,000 | 685,000 | 1,420,000 | 686,000 | 686,000 | 766,000 | 766,000 | 684,000 | 573,000 | 573,000 | 477,000 | 477,000 | 309,000 | 309,000 | 263,000 | 290,000 | 285,000 | 280,000 | ||||||||||||||||||||||||||||||||||||||||
research and development | 298,655,000 | 199,164,000 | 200,356,000 | 212,233,000 | 249,002,000 | 222,570,000 | 222,570,000 | 211,147,000 | 211,147,000 | 227,689,000 | 227,689,000 | 244,670,000 | 332,585,000 | 332,585,000 | 232,570,000 | 234,246,000 | 336,824,000 | 198,837,000 | 199,481,000 | 199,481,000 | 156,671,000 | 156,671,000 | 222,268,000 | 163,370,000 | 163,370,000 | 148,790,000 | 148,790,000 | 159,288,000 | 159,288,000 | -56,608,000 | 176,762,000 | 176,762,000 | 114,933,000 | 114,933,000 | 101,877,000 | 101,877,000 | 97,295,000 | 97,295,000 | 81,932,000 | 81,932,000 | 63,289,000 | 63,289,000 | 57,271,000 | 44,741,000 | 42,488,000 | 37,757,000 | 32,204,000 | 28,543,000 | 28,214,000 | 23,210,000 | 23,801,000 | 20,256,000 | 22,984,000 | 28,926,000 | 26,091,000 | 24,506,000 | 24,506,000 | 22,282,000 | 22,282,000 | 39,650,000 | 43,628,000 | 43,628,000 | 50,976,000 | 50,976,000 | 54,847,000 | 54,847,000 | 49,597,000 | 47,354,000 | 49,077,000 | 32,735,000 | 32,492,000 | 30,680,000 | 32,610,000 | 33,096,000 | 30,778,000 | 37,465,000 | 42,901,000 | 45,691,000 | 66,327,000 | 49,388,000 | 54,237,000 | 64,751,000 | 86,823,000 | 60,186,000 | 55,036,000 | 55,344,000 | 65,670,000 | 68,869,000 | 65,973,000 | 60,216,000 | 58,643,000 | 56,306,000 | 50,210,000 | 52,137,000 | 46,048,000 | 47,399,000 | 39,897,000 | 36,044,000 | 35,202,000 | 36,568,000 | 33,321,000 | 35,030,000 | 34,054,000 | 34,416,000 | 34,224,000 | 32,298,000 | 32,453,000 | |||
selling, general and administrative | 96,425,000 | 123,661,000 | 134,859,000 | 137,183,000 | 134,328,000 | 111,801,000 | 111,801,000 | 132,015,000 | 132,015,000 | 113,984,000 | 113,984,000 | 131,441,000 | 138,144,000 | 138,144,000 | 141,723,000 | 131,397,000 | 119,251,000 | 114,983,000 | 122,759,000 | 122,759,000 | 102,863,000 | 102,863,000 | 99,311,000 | 101,558,000 | 101,558,000 | 98,495,000 | 98,495,000 | 102,351,000 | 102,351,000 | 17,328,000 | 88,185,000 | 88,185,000 | 59,791,000 | 59,791,000 | 62,940,000 | 62,940,000 | 51,265,000 | 51,265,000 | 58,815,000 | 58,815,000 | 60,138,000 | 60,138,000 | 52,377,000 | 48,120,000 | 51,853,000 | 52,643,000 | 46,246,000 | 38,129,000 | 40,727,000 | 34,260,000 | 13,002,000 | 32,463,000 | 35,823,000 | 34,857,000 | 17,842,000 | 12,789,000 | 12,789,000 | 9,531,000 | 9,531,000 | 9,766,000 | 9,906,000 | 9,906,000 | 16,466,000 | 16,466,000 | 14,691,000 | 14,691,000 | 13,635,000 | 13,598,000 | 13,180,000 | 10,545,000 | 4,495,000 | 4,701,000 | ||||||||||||||||||||||||||||||||||||||
impairment of long-lived assets | 51,672,000 | 51,672,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
restructuring | 13,844,000 | 19,816,000 | 254,000 | 96,000 | 96,000 | 475,000 | 475,000 | 32,835,000 | 32,835,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
total operating expenses | 479,596,000 | 361,215,000 | 354,685,000 | 368,588,000 | 403,549,000 | 403,467,000 | 403,467,000 | 361,304,000 | 361,304,000 | 395,764,000 | 395,764,000 | 397,864,000 | 489,503,000 | 489,503,000 | 391,998,000 | 379,958,000 | 471,995,000 | 329,125,000 | 335,721,000 | 335,721,000 | 272,737,000 | 272,737,000 | 334,496,000 | 276,802,000 | 276,802,000 | 262,169,000 | 262,169,000 | 274,837,000 | 274,837,000 | -33,418,000 | 273,672,000 | 273,672,000 | 183,945,000 | 183,945,000 | 174,106,000 | 174,106,000 | 156,097,000 | 156,097,000 | 148,286,000 | 148,286,000 | 130,928,000 | 130,928,000 | 117,000,000 | 100,221,000 | 100,338,000 | 96,039,000 | 82,641,000 | 71,330,000 | 71,895,000 | 60,701,000 | 38,698,000 | 54,930,000 | 61,388,000 | 64,562,000 | 45,635,000 | 39,272,000 | 39,272,000 | 32,148,000 | 32,148,000 | 53,561,000 | 57,865,000 | 57,865,000 | 68,250,000 | 68,250,000 | 69,893,000 | 69,893,000 | 63,861,000 | 61,379,000 | 63,151,000 | 43,679,000 | 49,788,000 | 38,756,000 | 40,536,000 | 40,806,000 | 41,734,000 | 48,573,000 | 50,170,000 | 59,623,000 | 52,110,000 | 58,679,000 | 73,227,000 | 89,651,000 | 97,888,000 | 71,794,000 | 65,414,000 | 62,076,000 | 74,537,000 | 79,097,000 | 74,664,000 | 72,012,000 | 69,451,000 | 67,561,000 | 61,493,000 | 63,524,000 | 55,101,000 | 57,623,000 | 49,176,000 | 43,873,000 | 42,292,000 | 43,952,000 | 39,835,000 | 66,838,000 | 39,300,000 | 41,418,000 | 40,503,000 | 37,565,000 | 37,321,000 | |||
income from operations | -32,358,000 | 236,540,000 | 213,576,000 | 186,859,000 | 163,206,000 | 136,075,000 | 136,075,000 | 275,874,000 | 275,874,000 | 29,462,000 | 29,462,000 | 81,788,000 | -17,583,000 | -17,583,000 | 77,850,000 | 28,830,000 | -48,078,000 | 82,613,000 | 83,706,000 | 83,706,000 | 83,243,000 | 83,243,000 | 116,644,000 | 51,621,000 | 51,621,000 | 123,008,000 | 123,008,000 | -4,607,000 | -4,607,000 | 283,707,000 | -42,580,000 | -42,580,000 | 75,534,000 | 75,534,000 | 52,809,000 | 52,809,000 | 115,606,000 | 115,606,000 | 91,989,000 | 91,989,000 | 84,559,000 | 84,559,000 | 111,602,000 | 125,176,000 | 85,770,000 | 116,307,000 | 37,431,000 | 81,180,000 | 27,113,000 | 20,186,000 | 38,883,000 | 7,264,000 | -25,136,000 | -49,135,000 | -35,781,000 | -31,280,000 | -31,280,000 | -22,760,000 | -22,760,000 | -46,208,000 | -51,574,000 | -51,574,000 | -61,688,000 | -61,688,000 | -64,988,000 | -64,988,000 | -59,514,000 | -55,913,000 | -51,295,000 | -34,010,000 | -41,974,000 | -25,443,000 | -32,723,000 | -22,296,000 | -18,008,000 | -23,730,000 | -44,620,000 | -4,205,000 | -25,631,000 | -47,452,000 | -87,710,000 | -16,818,000 | -38,012,000 | -36,774,000 | -44,605,000 | -48,685,000 | -46,720,000 | -42,762,000 | -42,626,000 | -38,302,000 | -33,357,000 | -33,753,000 | -31,561,000 | -30,383,000 | -31,057,000 | -29,496,000 | -27,892,000 | -9,642,000 | -26,961,000 | |||||||||||
yoy | -119.83% | 73.83% | 56.95% | -32.27% | -40.84% | 361.87% | 361.87% | 237.30% | -267.56% | -267.56% | 183.69% | -63.43% | -5.77% | -65.56% | -157.76% | -0.76% | -28.24% | 62.15% | 61.26% | -32.33% | -5.17% | -1220.49% | -1220.49% | -56.64% | -89.18% | -89.18% | 275.60% | -180.63% | -180.63% | -34.66% | -34.66% | -42.59% | -42.59% | 36.72% | 36.72% | -17.57% | -26.51% | -1.41% | -27.30% | 198.15% | 54.20% | 216.34% | 476.18% | -3.73% | 1017.57% | -207.87% | -141.08% | -208.67% | -123.22% | -19.64% | 115.88% | 57.21% | -32.31% | -39.35% | -55.87% | -63.10% | -25.09% | -20.64% | -20.64% | 3.65% | 10.33% | 26.69% | 91.08% | 41.79% | 119.76% | 56.76% | 52.54% | 81.71% | -6.04% | -29.74% | -49.99% | -49.13% | -75.00% | -32.57% | 29.04% | 96.64% | -65.46% | -18.64% | -14.00% | 4.64% | 27.11% | 40.06% | 26.69% | 35.06% | 26.06% | 7.41% | 14.43% | 13.15% | 215.11% | 15.19% | ||||||||||||||||||||
qoq | -113.68% | 10.75% | 14.30% | 14.49% | 19.94% | 0.00% | -50.67% | 0.00% | 836.37% | 0.00% | -565.15% | 0.00% | -122.59% | 170.03% | -158.20% | -1.31% | 0.00% | 0.56% | 0.00% | -28.63% | 125.96% | 0.00% | -58.03% | 0.00% | -2770.02% | 0.00% | -766.29% | 0.00% | -156.37% | 0.00% | 43.03% | 0.00% | -54.32% | 0.00% | 25.67% | 0.00% | 8.79% | 0.00% | -24.23% | -10.84% | 45.94% | -26.26% | 210.72% | -53.89% | 199.41% | 34.32% | -48.09% | 435.28% | -128.90% | -48.84% | 37.32% | 14.39% | 0.00% | 37.43% | 0.00% | -50.74% | -10.40% | 0.00% | -16.40% | 0.00% | -5.08% | 0.00% | 9.20% | 6.44% | 9.00% | 50.82% | -18.97% | 64.97% | -22.25% | 46.77% | -24.11% | -46.82% | 961.12% | -83.59% | -45.99% | -45.90% | 421.52% | -55.76% | 3.37% | -17.56% | -8.38% | 4.21% | 9.26% | 0.32% | 11.29% | 14.82% | -1.17% | 6.95% | 3.88% | -2.17% | 5.29% | 5.75% | 189.28% | -64.24% | ||||||||||||||||
operating margin % | -7.24% | 39.57% | 37.58% | 33.64% | 28.80% | 25.22% | 25.22% | 43.30% | 43.30% | 6.93% | 6.93% | 17.05% | -3.73% | -3.73% | 16.57% | 7.05% | -11.34% | 20.06% | 19.96% | 19.96% | 23.38% | 23.38% | 25.86% | 15.72% | 15.72% | 31.94% | 31.94% | -1.70% | -1.70% | 113.35% | -18.43% | -18.43% | 29.11% | 29.11% | 23.27% | 23.27% | 42.55% | 42.55% | 38.28% | 38.28% | 39.24% | 39.24% | 48.82% | 55.54% | 46.09% | 54.77% | 31.17% | 53.23% | 27.38% | 24.96% | 50.12% | 11.68% | -69.34% | -318.50% | -363.11% | -628.42% | -819.81% | -819.81% | -940.08% | -940.08% | -1324.93% | -1324.93% | -1369.08% | -1022.92% | -432.65% | -351.74% | -537.16% | -191.11% | -418.83% | -120.45% | 0% | 0% | -55.99% | -66.11% | -595.73% | -7.72% | -53.85% | -112.45% | -861.76% | -30.59% | -138.72% | -145.34% | -149.02% | -160.08% | -167.19% | -146.19% | -158.90% | -130.91% | -118.56% | -113.38% | -134.07% | -111.54% | -171.41% | -205.16% | -193.69% | -28.10% | -209.42% | 0% | ||||||||||||
interest income | 25,369,000 | 15,922,000 | 16,789,000 | 19,076,000 | 21,295,000 | 18,709,000 | 18,709,000 | 17,258,000 | 17,258,000 | 19,894,000 | 19,894,000 | 21,388,000 | 23,112,000 | 23,112,000 | 22,541,000 | 19,502,000 | 16,988,000 | 9,498,000 | 4,757,000 | 4,757,000 | 1,822,000 | 1,822,000 | 1,441,000 | 1,658,000 | 1,658,000 | 1,891,000 | 1,891,000 | 2,682,000 | 2,682,000 | 11,583,000 | 3,994,000 | 3,994,000 | 5,162,000 | 5,162,000 | 7,220,000 | 7,220,000 | 7,191,000 | 7,191,000 | 6,975,000 | 6,975,000 | 6,087,000 | 6,087,000 | 4,741,000 | 3,507,000 | 2,697,000 | 1,895,000 | 2,722,000 | 1,892,000 | 1,993,000 | 1,944,000 | 1,821,000 | 1,581,000 | 1,046,000 | 928,000 | 806,000 | 728,000 | 782,000 | 916,000 | 1,096,000 | 1,042,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||
other incomes | -61,000 | -49,000 | -245,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income before income taxes | -6,878,000 | 252,413,000 | 230,415,000 | 205,690,000 | 184,773,000 | 154,755,000 | 154,755,000 | 292,845,000 | 292,845,000 | 49,267,000 | 49,267,000 | 103,039,000 | 5,818,000 | 5,818,000 | 100,386,000 | 48,278,000 | -31,427,000 | 92,042,000 | 88,508,000 | 88,508,000 | 85,229,000 | 85,229,000 | 118,021,000 | 53,260,000 | 53,260,000 | 124,888,000 | 124,888,000 | -2,015,000 | -2,015,000 | 295,399,000 | -38,021,000 | -38,021,000 | 80,696,000 | 80,696,000 | 60,035,000 | 60,035,000 | 122,657,000 | 122,657,000 | 99,767,000 | 99,767,000 | 90,671,000 | 90,671,000 | 116,372,000 | 128,954,000 | 88,395,000 | 118,371,000 | 38,918,000 | 84,588,000 | 18,237,000 | 16,834,000 | -70,842,000 | -67,124,000 | -62,161,000 | -44,729,000 | -52,119,000 | -32,804,000 | -36,475,000 | -26,140,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
benefit from income taxes | 9,897,000 | 58,835,000 | 45,567,000 | 46,074,000 | 44,912,000 | 36,782,000 | 36,782,000 | 66,729,000 | 66,729,000 | 11,950,000 | 11,950,000 | 17,521,000 | 4,777,000 | 4,777,000 | 19,208,000 | 8,250,000 | -1,254,000 | 18,832,000 | 17,836,000 | 17,836,000 | 16,656,000 | 16,656,000 | 22,855,000 | 15,056,000 | 15,056,000 | 28,796,000 | 28,796,000 | -3,616,000 | -3,616,000 | 4,829,250 | -5,981,000 | -5,981,000 | 13,875,000 | 13,875,000 | 11,423,000 | 11,423,000 | -25,205,000 | -25,205,000 | -20,725,000 | -20,725,000 | -14,896,000 | -14,896,000 | 1,434,750 | 2,324,000 | 901,000 | 2,514,000 | 92,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
net income | -16,775,000 | 193,578,000 | 184,848,000 | 159,616,000 | 139,861,000 | 117,973,000 | 117,973,000 | 226,116,000 | 226,116,000 | 37,317,000 | 37,317,000 | 85,518,000 | 1,041,000 | 1,041,000 | 81,178,000 | 40,028,000 | -30,173,000 | 73,210,000 | 70,672,000 | 70,672,000 | 68,573,000 | 68,573,000 | 95,166,000 | 38,204,000 | 38,204,000 | 96,092,000 | 96,092,000 | 1,601,000 | 1,601,000 | 237,619,000 | -32,040,000 | -32,040,000 | 66,821,000 | 66,821,000 | 48,612,000 | 48,612,000 | 97,452,000 | 97,452,000 | 79,042,000 | 79,042,000 | 75,775,000 | 75,775,000 | 360,089,000 | 126,630,000 | 87,494,000 | 115,857,000 | 38,489,000 | 81,382,000 | 17,656,000 | 16,700,000 | 35,123,000 | -11,284,000 | -37,015,000 | -61,347,000 | -47,564,000 | -43,362,000 | -43,362,000 | -35,170,000 | -35,170,000 | -57,953,000 | -62,560,000 | -62,560,000 | -73,410,000 | -73,410,000 | -74,619,000 | -74,619,000 | -70,746,000 | -67,124,000 | -62,161,000 | -44,729,000 | -52,193,000 | -32,814,000 | -36,487,000 | -26,151,000 | 7,350,250 | 77,865,000 | -20,975,000 | -27,490,000 | -38,506,000 | -45,124,000 | -41,274,000 | -19,922,000 | -13,696,000 | -28,562,000 | -24,201,000 | -25,182,000 | -25,197,000 | -23,990,000 | -27,123,000 | -24,522,000 | -22,775,000 | -9,696,000 | -27,411,000 | -51,922,000 | -27,189,000 | -28,843,000 | -24,995,000 | -23,442,000 | ||||||||||||
yoy | -111.99% | 64.09% | 56.69% | -29.41% | -38.15% | 216.14% | 216.14% | 164.41% | 3484.73% | 3484.73% | 113.65% | -103.45% | 10.88% | -43.36% | -144.00% | 6.76% | -25.74% | 84.99% | 79.49% | -28.64% | -0.96% | 2286.26% | 2286.26% | -59.56% | -105.00% | -105.00% | 255.61% | -165.91% | -165.91% | -31.43% | -31.43% | -38.50% | -38.50% | 28.61% | 28.61% | -78.05% | -37.58% | -13.39% | -34.60% | 835.56% | 55.60% | 395.55% | 593.75% | 9.58% | -821.22% | -147.70% | -127.22% | -173.84% | -73.98% | -14.64% | 74.43% | 35.24% | -25.18% | -30.69% | -43.78% | -52.09% | -21.06% | -16.16% | -16.16% | 3.77% | 9.36% | 20.04% | 66.82% | 35.55% | 104.56% | 70.36% | 71.04% | -810.08% | -142.14% | 73.95% | -4.87% | 181.15% | 57.99% | 70.55% | -20.89% | -45.64% | 19.06% | -10.77% | 2.69% | 10.63% | 147.42% | -1.05% | -52.77% | -16.23% | -4.96% | 107.73% | 15.98% | |||||||||||||||||||||||
qoq | -108.67% | 4.72% | 15.81% | 14.12% | 18.55% | 0.00% | -47.83% | 0.00% | 505.93% | 0.00% | 8114.99% | 0.00% | -98.72% | 102.80% | -141.21% | 3.59% | 0.00% | 3.06% | 0.00% | -27.94% | 149.10% | 0.00% | -60.24% | 0.00% | 5902.00% | 0.00% | -841.63% | 0.00% | -147.95% | 0.00% | 37.46% | 0.00% | -50.12% | 0.00% | 23.29% | 0.00% | 4.31% | 0.00% | -78.96% | 184.36% | 44.73% | -24.48% | 201.01% | -52.71% | 360.93% | 5.72% | -52.45% | -411.26% | -69.52% | -39.66% | 28.98% | 9.69% | 0.00% | 23.29% | 0.00% | -39.31% | -7.36% | 0.00% | -14.78% | 0.00% | -1.62% | 0.00% | 5.47% | 5.40% | 7.98% | 38.97% | -14.30% | 59.06% | -10.07% | 39.52% | -455.78% | -90.56% | -471.23% | -23.70% | -14.67% | 9.33% | 107.18% | 45.46% | -52.05% | 18.02% | -3.90% | -0.06% | 5.03% | -11.55% | 10.61% | 7.67% | 134.89% | -64.63% | -47.21% | 90.97% | 15.40% | 6.62% | ||||||||||||||||||
net income margin % | -3.75% | 32.38% | 32.53% | 28.74% | 24.68% | 21.87% | 21.87% | 35.49% | 35.49% | 8.78% | 8.78% | 17.83% | 0.22% | 0.22% | 17.28% | 9.79% | -7.12% | 17.78% | 16.85% | 16.85% | 19.26% | 19.26% | 21.09% | 11.63% | 11.63% | 24.95% | 24.95% | 0.59% | 0.59% | 94.94% | -13.86% | -13.86% | 25.75% | 25.75% | 21.42% | 21.42% | 35.87% | 35.87% | 32.90% | 32.90% | 35.16% | 35.16% | 157.52% | 56.18% | 47.01% | 54.56% | 32.05% | 53.36% | 17.83% | 20.65% | 45.27% | -18.14% | -102.10% | -397.66% | -482.69% | -788.15% | -994.44% | -994.44% | -1118.71% | -1118.71% | -1521.28% | -1521.28% | -1627.47% | -1228.03% | -524.30% | -462.60% | -667.94% | -246.48% | -467.00% | -141.28% | 7.88% | 60.70% | -65.22% | -76.59% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | -128.64% | -148.38% | -147.70% | -68.11% | -51.06% | -97.62% | -86.01% | -84.59% | -107.04% | -88.07% | -149.69% | -170.56% | -158.16% | -28.26% | -212.92% | -329.79% | -214.73% | -242.54% | -200.94% | -180.25% | ||||||||
net income per share | 0.32 | 0.32 | 0.26 | 0.26 | 0.25 | 0.25 | 1.21 | 0.42 | 0.29 | 0.39 | 0.13 | 0.28 | 0.06 | 0.06 | 0.16 | -0.04 | -0.16 | -0.27 | -0.22 | -0.22 | -0.22 | -0.18 | -0.18 | -0.29 | -0.32 | -0.32 | -0.38 | -0.38 | -0.39 | -0.39 | -0.38 | -0.36 | -0.34 | -0.24 | -0.29 | -0.2 | -0.25 | -0.18 | 0.36 | 0.6 | -0.16 | -0.24 | -0.57 | -0.08 | -0.21 | -0.4 | -0.54 | -0.24 | -0.42 | -0.34 | -0.36 | -0.43 | -0.39 | -0.19 | -0.14 | -0.29 | -0.25 | -0.26 | -0.3 | -0.29 | -0.32 | -0.3 | -0.29 | -0.13 | -0.36 | -0.7 | -0.38 | -0.4 | -0.35 | -0.39 | ||||||||||||||||||||||||||||||||||||||||
basic | -0.17 | 0.72 | 0.68 | 0.57 | 0.49 | 0.41 | 0.41 | 0.78 | 0.78 | 0.12 | 0.12 | 0.27 | 0 | 0 | 0.25 | 0.12 | -0.09 | 0.23 | 0.22 | 0.22 | 0.21 | 0.21 | 0.3 | 0.12 | 0.12 | 0.31 | 0.31 | 0.01 | 0.01 | 0.79 | -0.1 | -0.1 | 0.22 | 0.22 | 0.16 | 0.16 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
diluted | -0.14 | 0.69 | 0.65 | 0.55 | 0.48 | 0.4 | 0.4 | 0.77 | 0.77 | 0.12 | 0.12 | 0.27 | 0 | 0 | 0.25 | 0.12 | -0.09 | 0.23 | 0.22 | 0.22 | 0.21 | 0.21 | 0.3 | 0.12 | 0.12 | 0.3 | 0.3 | 0 | 0 | 0.76 | -0.1 | -0.1 | 0.21 | 0.21 | 0.15 | 0.15 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
weighted-average common shares outstanding: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
basic | 290,030 | 268,421 | 272,583 | 278,804 | 290,030 | 285,622 | 285,622 | 289,216 | 289,216 | 300,757 | 300,757 | 318,151 | 315,496 | 315,496 | 324,205 | 324,420 | 321,526 | 322,148 | 321,117 | 321,117 | 319,582 | 319,582 | 314,884 | 315,380 | 315,380 | 314,117 | 314,117 | 312,473 | 312,473 | 302,584 | 309,116 | 309,116 | 307,807 | 307,807 | 305,388 | 305,388 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
diluted | 296,132 | 278,535 | 284,393 | 288,177 | 296,132 | 291,478 | 291,478 | 293,974 | 293,974 | 305,530 | 305,530 | 321,464 | 319,247 | 319,247 | 327,305 | 326,279 | 324,556 | 325,066 | 324,904 | 324,904 | 323,289 | 323,289 | 322,359 | 322,022 | 322,022 | 322,941 | 322,941 | 321,287 | 321,287 | 315,009 | 309,116 | 309,116 | 318,144 | 318,144 | 315,839 | 315,839 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
other income (expenses) | 50,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
license revenues | 49,343,000 | 60,239,000 | 60,239,000 | 194,986,000 | 194,986,000 | 44,676,000 | 44,676,000 | 45,229,000 | 42,367,000 | 42,367,000 | 52,747,000 | 38,292,000 | 38,079,000 | 34,384,000 | 57,526,000 | 57,526,000 | 32,067,000 | 32,067,000 | 133,094,000 | 49,694,000 | 49,694,000 | 39,640,000 | 39,640,000 | 27,528,000 | 27,528,000 | 28,329,500 | 33,205,000 | 33,205,000 | 59,234,000 | 59,234,000 | 20,879,000 | 20,879,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
collaboration services revenues | 2,180,000 | 1,244,000 | 1,244,000 | 4,611,000 | 4,611,000 | 2,027,000 | 2,027,000 | 5,087,000 | 3,056,000 | 3,056,000 | 7,455,000 | 7,096,000 | 8,419,000 | 10,872,000 | 14,857,000 | 14,857,000 | 13,615,000 | 13,615,000 | 15,367,000 | 15,612,000 | 15,612,000 | 61,289,000 | 61,289,000 | 15,490,000 | 15,490,000 | 15,742,750 | 29,300,000 | 29,300,000 | 21,515,000 | 21,515,000 | 12,156,000 | 12,156,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
other income | 272,000 | -29,000 | -29,000 | -287,000 | -287,000 | -89,000 | -89,000 | -137,000 | 289,000 | 289,000 | -5,000 | -54,000 | -337,000 | -69,000 | 45,000 | 45,000 | 164,000 | 164,000 | -64,000 | -19,000 | -19,000 | -11,000 | -11,000 | -90,000 | -90,000 | 142,750 | 565,000 | 565,000 | 6,000 | 6,000 | -7,250 | -3,000 | -32,000 | 6,000 | -195,000 | 16,000 | 174,000 | 5,000 | 6,000 | 7,000 | 85,000 | 838,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
collaboration revenue | 79,935,000 | 79,935,000 | 46,600,000 | 46,600,000 | 35,906,000 | 35,906,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
other income, net: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
other | -140,000 | -140,000 | 803,000 | 803,000 | 25,000 | 25,000 | 28,000 | 272,000 | -72,000 | 169,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
total other income, net: | 7,051,000 | 7,051,000 | 7,778,000 | 7,778,000 | 6,112,000 | 6,112,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
net income per share | 0.32 | 0.32 | 0.26 | 0.26 | 0.25 | 0.25 | 1.21 | 0.42 | 0.29 | 0.39 | 0.13 | 0.28 | 0.06 | 0.06 | 0.16 | -0.04 | -0.16 | -0.27 | -0.22 | -0.22 | -0.22 | -0.18 | -0.18 | -0.29 | -0.32 | -0.32 | -0.38 | -0.38 | -0.39 | -0.39 | -0.38 | -0.36 | -0.34 | -0.24 | -0.29 | -0.2 | -0.25 | -0.18 | 0.36 | 0.6 | -0.16 | -0.24 | -0.57 | -0.08 | -0.21 | -0.4 | -0.54 | -0.24 | -0.42 | -0.34 | -0.36 | -0.43 | -0.39 | -0.19 | -0.14 | -0.29 | -0.25 | -0.26 | -0.3 | -0.29 | -0.32 | -0.3 | -0.29 | -0.13 | -0.36 | -0.7 | -0.38 | -0.4 | -0.35 | -0.39 | ||||||||||||||||||||||||||||||||||||||||
shares used in computing net income per share, basic | 303,268 | 303,268 | 302,188 | 302,188 | 300,542 | 300,542 | 192 | 298,416 | 297,336 | 296,421 | 812 | 294,269 | 293,188 | 290,870 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
shares used in computing net income per share, diluted | 315,453 | 315,453 | 314,911 | 314,911 | 314,644 | 314,644 | -397 | 312,346 | 312,241 | 313,691 | 448 | 312,940 | 311,219 | 309,535 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
interest expense | -250 | -1,000 | -4,259,000 | -4,420,000 | -4,485,000 | -7,834,000 | -12,628,000 | -12,414,000 | -12,059,000 | -11,959,000 | -11,959,000 | -12,403,000 | -12,403,000 | -12,482,000 | -12,282,000 | -12,282,000 | -12,081,000 | -12,081,000 | -11,762,000 | -11,762,000 | -11,621,000 | -11,430,000 | -11,239,000 | -11,057,000 | -11,313,000 | -7,679,000 | -4,092,000 | -4,004,000 | -4,010,000 | -4,142,000 | -4,164,000 | -3,943,000 | -7,294,000 | -4,094,000 | -673,000 | -612,000 | -406,000 | -2,122,000 | -2,118,000 | -2,116,000 | -2,171,000 | -1,254,000 | -961,000 | -965,000 | -970,000 | -1,004,000 | -1,027,000 | -985,750 | -1,071,000 | -1,338,000 | -1,534,000 | -1,543,000 | -1,550,000 | -1,545,000 | -1,552,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
total other income | 2,116,750 | 3,778,000 | 2,625,000 | 2,064,000 | -2,205,000 | 3,408,000 | -8,876,000 | -3,352,000 | -3,760,000 | -18,548,000 | -11,879,000 | -12,212,000 | -11,783,000 | -12,082,000 | -12,082,000 | -12,410,000 | -12,410,000 | -11,927,000 | -10,986,000 | -10,986,000 | -11,722,000 | -11,722,000 | -9,631,000 | -9,631,000 | -11,328,000 | -11,211,000 | -10,866,000 | -10,719,000 | -10,145,000 | -7,361,000 | -3,752,000 | -3,844,000 | -3,983,000 | -1,834,000 | -2,967,000 | -3,760,000 | -21,686,000 | -4,470,000 | 3,017,000 | 4,203,000 | 16,849,000 | -1,767,000 | -9,777,000 | -1,562,000 | 3,419,000 | 217,000 | 1,550,000 | 20,432,000 | 20,746,000 | 2,280,000 | 2,567,000 | 1,708,000 | 818,000 | 623,000 | 416,000 | 83,000 | 31,000 | -483,000 | -450,000 | 56,000 | 966,000 | |||||||||||||||||||||||||||||||||||||||||||||||||
restructuring (recovery) charge | -60,000 | 217,750 | -244,000 | -431,000 | -431,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
interest income and other | 1,524,500 | 3,408,000 | 1,622,000 | 1,068,000 | 853,000 | 3,059,000 | 749,000 | 202,000 | 276,000 | -123,000 | -123,000 | -7,000 | -7,000 | 555,000 | 1,296,000 | 1,296,000 | 359,000 | 359,000 | 2,131,000 | 2,131,000 | 293,000 | 219,000 | 373,000 | 338,000 | 1,168,000 | 318,000 | 340,000 | 160,000 | -17,000 | 98,000 | 1,197,000 | 183,000 | 1,179,000 | -376,000 | 393,000 | 315,000 | 4,659,000 | 355,000 | 367,000 | 554,000 | 1,090,000 | 1,471,000 | 2,511,000 | 3,269,000 | 2,908,000 | 3,284,000 | 3,594,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss on extinguishment of debt | -1,559,750 | -6,239,000 | -128,000 | -13,773,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income tax expense | 980,250 | 3,206,000 | 581,000 | 134,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
restructuring charges | 28,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
royalty, license and contract revenues | 7,603,500 | 19,452,000 | 4,634,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
shares used in computing basic and diluted net income per share | 12,507 | 256,319 | 229,310 | 228,304 | 217,587 | 196,201 | 196,201 | 195,904 | 195,904 | 48,463.75 | 195,126 | 195,126 | 194,929 | 194,929 | 191,699 | 191,699 | 45,989.25 | 184,149 | 183,981 | 183,742 | 104,993 | 96,411 | 20,993 | 84,178 | 84,054 | 83,678 | 19,322 | 79,540 | 76,405 | 75,918 | 17,974.5 | 72,170 | 72,011 | 71,512 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
restructuring charge | 1,021,000 | 94,000 | 282,000 | 1,291,000 | 1,291,000 | 1,033,750 | 3,758,000 | 3,758,000 | 331,000 | 331,000 | 46,000 | 46,000 | 366,000 | 137,000 | 609,000 | 119,000 | 7,467,000 | 733,000 | 1,166,000 | 3,946,000 | 2,937,000 | -1,514,000 | 4,767,000 | 6,455,750 | 339,000 | 9,419,000 | 16,065,000 | 1,738,000 | 537,000 | 606,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
license and contract revenues | 6,328,000 | 4,080,250 | 695,000 | 7,813,000 | 7,813,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
contract revenues | 3,000,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income tax provision | -8,250 | -10,000 | -12,000 | -11,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
contract | 3,802,000 | 9,301,000 | 3,802,000 | 3,831,000 | 15,548,000 | 5,024,000 | 8,327,000 | 12,410,000 | 10,226,000 | 11,865,000 | 12,308,000 | 19,740,000 | 33,451,000 | 24,608,000 | 6,299,000 | 6,706,000 | 16,665,000 | 16,757,000 | 18,626,000 | 19,983,000 | 17,496,000 | 16,378,000 | 15,166,000 | 19,805,000 | 13,347,000 | 17,016,000 | 12,246,000 | 10,392,000 | 10,279,000 | 24,954,000 | 10,090,000 | 13,528,000 | 10,617,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
license | 4,012,000 | 4,012,000 | 4,011,000 | 14,679,000 | 77,565,000 | 122,703,000 | 22,492,000 | 22,789,000 | 23,970,000 | 24,542,000 | 24,542,000 | 24,565,000 | -23,273,000 | 30,368,000 | 21,103,000 | 18,596,000 | 13,267,000 | 13,655,000 | 9,318,000 | 9,267,000 | 9,329,000 | 12,881,000 | 12,970,000 | 9,966,000 | 10,193,000 | 10,224,000 | 5,873,000 | 3,985,000 | 4,121,000 | 9,356,000 | 2,784,000 | 2,216,000 | 2,045,000 | 3,128,000 | 3,128,000 | 3,129,000 | 3,128,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
collaboration reimbursement | 694,000 | -2,106,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
general and administrative | 9,829,000 | 7,343,000 | 6,760,000 | 7,905,000 | 7,010,000 | 8,171,000 | 8,783,000 | 9,165,000 | 7,024,000 | 8,952,000 | 9,571,000 | 8,835,000 | 10,982,000 | 8,643,000 | 8,739,000 | 8,529,000 | 8,867,000 | 10,228,000 | 8,691,000 | 11,789,000 | 10,757,000 | 11,183,000 | 11,211,000 | 11,289,000 | 8,843,000 | 9,984,000 | 9,007,000 | 7,558,000 | 6,819,000 | 7,112,000 | 6,242,000 | 5,549,000 | 5,078,000 | 4,702,000 | 5,576,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
gain on sale of business | 552,500 | 2,210,000 | 1,949,250 | 3,297,000 | 4,500,000 | 450,000 | 1,800,000 | 4,500,000 | 4,702,000 | 18,808,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
shares used in computing basic income per share amounts | 7,822 | 166,354 | 2,592 | 129,145 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
shares used in computing diluted income per share amounts | 7,822 | 166,354 | 1,049 | 131,344 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
shares used in computing basic and diluted loss per share amounts | 148,654 | 141,940 | 128,245 | 113,215 | -1,300 | 108,667 | 108,476 | 107,976 | -1,355 | 107,336 | 106,840 | 106,383 | 105,548 | 105,340 | 1,834 | 98,551 | 96,976 | 70,994 | 60,141 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
restructuring (credit) charge | -195,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
other income: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
collaboration reimbursements | 645,750 | 545,000 | 1,343,000 | 6,676,500 | 18,067,000 | 10,746,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
gain from operations | 9,490,250 | 79,699,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
consolidated income before taxes | 47,591,000 | 77,865,000 | -66,306,000 | -8,675,000 | -22,614,000 | -26,177,250 | -18,585,000 | -47,789,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income tax benefit | 18,000 | 72,000 | 846,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
collaboration cost sharing | 701,750 | 2,965,000 | 1,639,000 | -1,797,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss on deconsolidation of symphony evolution, inc. | -2,456,500 | -9,826,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
consolidated net income | -65,092,000 | -8,603,000 | -22,614,000 | -43,249,000 | -27,680,750 | -25,445,000 | -46,943,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss attributable to noncontrolling interest. | 1,084,250 | 2,181,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
net income attributable to exelixis, inc. | -60,755,000 | -8,603,000 | -22,614,000 | -43,249,000 | -26,596,500 | -25,445,000 | -44,762,000 | -36,180,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss attributable to noncontrolling interest | 2,156,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
tax provision | -1,503,500 | -6,860,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
consolidated net income. | -38,336,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
amortization of intangible assets | 7,000 | 51,000 | 72,000 | 72,000 | 272,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income before noncontrolling interest in symphony evolution, inc. | -41,186,000 | -48,468,000 | -45,170,000 | -22,330,000 | -21,880,000 | -36,022,000 | -30,790,000 | -30,641,000 | -29,413,000 | -27,861,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss attributed to noncontrolling interest in symphony evolution, inc. | 2,680,000 | 3,344,000 | 3,896,000 | 2,408,000 | 8,184,000 | 7,460,000 | 6,589,000 | 3,518,000 | 4,891,000 | 5,086,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
amortization of intangibles | 180,500 | 210,000 | 240,000 | 203,750 | 271,000 | 272,000 | 272,000 | 125,250 | 168,000 | 167,000 | 166,000 | 166,000 | 167,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income before noncontrolling interest | -22,786,000 | -30,743,000 | -29,760,000 | -10,125,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss attributed to noncontrolling interest | 3,708,500 | 5,546,000 | 5,770,000 | 429,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
acquired in-process research and development | 25,981,000 | 395,000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
benefit for income taxes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
contracts | 9,431,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
contract and government grants | 8,764,000 | 9,310,000 | 9,877,000 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income from continuing operations before income taxes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income from continuing operations | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
income from operations of discontinued segment | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss per share from continuing operations | -0.35 | -0.39 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
loss per share from discontinued operations |
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