7Baggers
Quarterly
Annual
    Unit: USD2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 
      
    		                               
      operating expenses:
    		                               
      research and development
    		101,950,000 102,696,000 116,227,000 99,787,000 98,238,000 91,399,000 107,016,000 107,803,000 89,737,000 97,520,000 128,816,000 92,111,000 87,786,000 92,737,000 86,098,000 67,876,000 71,559,000 65,711,000 60,207,000 54,743,000 53,704,000 53,152,000 51,016,000 51,551,000 52,544,000 51,884,000 37,403,000 39,909,000 30,321,000 52,134,000 20,819,000 
      general and administrative
    		35,484,000 32,267,000 29,353,000 30,059,000 24,949,000 25,194,000 25,236,000 24,769,000 25,325,000 26,120,000 27,140,000 23,516,000 23,259,000 21,159,000 22,541,000 21,759,000 19,319,000 19,045,000 18,936,000 17,994,000 15,805,000 13,972,000 12,555,000 10,879,000 11,215,000 15,076,000 9,310,000 11,045,000 8,838,000 6,896,000 5,570,000 
      total operating expenses
    		137,434,000 134,963,000 145,580,000 129,846,000 123,187,000 116,593,000 132,252,000 132,572,000 115,062,000 123,640,000 155,956,000 115,627,000 111,045,000 113,896,000 108,639,000 89,635,000 90,878,000 84,756,000 79,143,000 72,737,000 69,509,000 67,124,000 63,571,000 62,430,000 63,759,000 66,960,000 46,713,000 50,954,000 39,159,000 59,030,000 26,389,000 
      gain from divestiture of small molecule programs
    		      14,537,000                         
      income from operations
    		-137,434,000 -134,963,000 -145,580,000 -129,846,000 -123,187,000 -116,593,000 -117,715,000 -132,572,000 -113,795,000 170,483,000 -120,815,000 -105,344,000 -107,486,000 -61,416,000 -66,498,000 -77,121,000 -85,593,000 -61,817,000 -71,220,000 244,078,000 -60,116,000 -61,277,000 -59,967,000 -57,758,000 -50,155,000 -62,763,000 -42,508,000 74,722,000 -37,964,000 -57,382,000 -25,748,000 
      yoy
    		11.57% 15.76% 23.67% -2.06% 8.25% -168.39% -2.57% 25.85% 5.87% -377.59% 81.68% 36.60% 25.58% -0.65% -6.63% -131.60% 42.38% 0.88% 18.77% -522.59% 19.86% -2.37% 41.07% -177.30% 32.11% 9.38% 65.09%     
      qoq
    		1.83% -7.29% 12.12% 5.41% 5.66% -0.95% -11.21% 16.50% -166.75% -241.11% 14.69% -1.99% 75.01% -7.64% -13.77% -9.90% 38.46% -13.20% -129.18% -506.01% -1.89% 2.18% 3.82% 15.16% -20.09% 47.65% -156.89% -296.82% -33.84% 122.86%  
      operating margin %
    		        -8981.45% 57.96% -343.80% -1024.45% -3020.12% -117.03% -157.80% -616.28% -1619.55% -269.48% -898.90% 77.04% -640.01% -1048.01% -1663.90%         
      interest and other income
    		10,532,000 10,844,000 12,610,000 15,161,000 15,995,000 17,567,000 15,913,000 13,129,000 14,442,000 12,900,000 11,034,000 6,660,000 4,187,000 2,649,000 1,278,000 1,285,000 1,005,000 1,126,000 1,179,000 1,630,000 1,944,000 2,598,000 3,069,000 3,808,000 3,782,000 4,113,000 3,516,000 2,811,000 2,593,000 2,658,000  
      net income
    		-126,902,000 -124,119,000 -132,970,000 -114,753,000 -107,192,000 -99,026,000 -101,802,000 -119,473,000 -99,353,000 183,383,000 -109,781,000 -98,678,000 -103,299,000 -58,794,000 -65,220,000 -75,261,000 -84,588,000 -60,691,000 -70,041,000 244,885,000 -58,228,000 -58,758,000 -56,763,000 -54,025,000 -46,260,000 -58,337,000 -38,992,000 77,533,000 -35,371,000 -54,724,000 -23,678,000 
      yoy
    		18.39% 25.34% 30.62% -3.95% 7.89% -154.00% -7.27% 21.07% -3.82% -411.91% 68.32% 31.11% 22.12% -3.13% -6.88% -130.73% 45.27% 3.29% 23.39% -553.28% 25.87% 0.72% 45.58% -169.68% 30.79% 6.60% 64.68%     
      qoq
    		2.24% -6.66% 15.87% 7.05% 8.25% -2.73% -14.79% 20.25% -154.18% -267.04% 11.25% -4.47% 75.70% -9.85% -13.34% -11.03% 39.37% -13.35% -128.60% -520.56% -0.90% 3.51% 5.07% 16.79% -20.70% 49.61% -150.29% -319.20% -35.36% 131.12%  
      net income margin %
    		        -7841.59% 62.35% -312.40% -959.62% -2902.47% -112.03% -154.77% -601.41% -1600.53% -264.58% -884.02% 77.30% -619.91% -1004.93% -1575.00%         
      net income per share
    		-0.74 -0.72 -0.78 -0.68 -0.63 -0.59 -0.68 -0.87 -0.72 1.34 -0.8 -0.463 -0.84 -0.48 -0.53 -0.443 -0.69 -0.5 -0.58 -0.413 -0.54 -0.56 -0.55 -0.57 -0.48 -0.61 -0.41 0.85 -0.38 -0.59 -0.26 
      weighted-average number of shares outstanding, basic and diluted
    		172,421,492 171,449,847 171,222,030 164,473,772 169,456,988  149,404,188 137,370,897 137,644,534  136,524,528  123,473,390 123,008,558 122,673,935  121,742,067 121,291,435 120,884,665  107,490,702 105,717,912 102,419,718 95,608,208 95,859,048 95,495,497 94,984,503 92,621,991 93,665,231 92,899,524 89,560,576 
      comprehensive loss
    		-126,740 -125,217 -132,953,000 -118,262,000 -99,004,000  -103,741,000 -118,179,000 -98,563,000  -105,412,000 -59,166,750 -102,878,000 -61,817,000 -71,972,000 -53,899,000 -84,741,000 -60,827,000 -70,028,000 -43,522,000 -58,768,000 -59,042,000 -56,278,000 -54,237,000 -46,577,000 -57,790,000 -38,011,000 78,300,000 -35,294,000 -54,930,000 -24,597,000 
      other comprehensive income:
    		                               
      net unrealized gain on marketable securities, net of tax
    		162  17,000 -3,509,000 8,188,000 -1,363,000 -1,939,000 1,294,000 790,000 1,076,000 4,369,000 -2,338,500 421,000  -6,752,000   -136,000 13,000 -256,000 -540,000 -284,000 485,000 -212,000 -317,000   767,000 77,000 -206,000  
      other comprehensive loss:
    		                               
      net unrealized loss on marketable securities, net of tax
    		 -1,098            -3,023,000  -69,000 -153,000              -919,000 
      collaboration revenue:
    		                               
      collaboration revenue from customers
    		        1,267,000 294,123,000 35,141,000 10,260,000 184,000 52,480,000 42,141,000 12,514,000 5,285,000 22,936,000 7,922,000 316,810,000 9,388,000 5,811,000 3,552,000         
      total collaboration revenue
    		        1,267,000 294,123,000 35,141,000 10,283,000 3,559,000 52,480,000 42,141,000 12,514,000 5,285,000 22,939,000 7,923,000 316,815,000 9,393,000 5,847,000 3,604,000         
      yoy
    		        -64.40% 460.45% -16.61% -17.83% -32.66% 128.78% 431.88% -96.05% -43.73% 292.32% 119.84%             
      qoq
    		        -99.57% 736.98% 241.74% 188.93% -93.22% 24.53% 236.75% 136.78% -76.96% 189.52% -97.50% 3272.88% 60.65% 62.24%          
      comprehensive income
    		     -100,389,000    184,459,000                      
      weighted-average shares used for eps calculation
    		                               
      weighted-average number of shares outstanding, basic
    		     168,831,329    137,047,227                      
      weighted-average number of shares outstanding, diluted
    		     168,831,329    140,930,625                      
      other collaboration revenue
    		           23,000 3,375,000     3,000 1,000 5,000 5,000 36,000 52,000         
      income before income taxes
    		       -119,443,000 -99,353,000 183,383,000  -98,684,000 -103,299,000 -58,767,000  -75,836,000 -84,588,000 -60,691,000 -70,041,000 245,708,000 -58,172,000 -58,679,000 -56,898,000 -53,950,000 -46,373,000 -58,650,000      
      income tax expense
    		           -6,750  -27,000                  
      income tax benefit
    		                    -56,000 -79,000 135,000 -75,000 113,000 313,000      
      collaboration revenue
    		                       4,672,000 13,604,000 4,197,000 4,205,000 125,676,000 1,195,000 1,648,000 641,000 
      net unrealized income on marketable securities, net of tax
    		                         547,000 981,000     
      interest income
    		                              2,070,000 
    The information provided in this report is taken from www.sec.gov and many other data providers. While we have conducted our best efforts to ensure that the parsed data is accurate, we cannot guarantee its accuracy. Please use caution and understand that any consequences of its use are your own responsibility.