7Baggers

Cryoport, Inc
(NASDAQ:CYRX) 

CYRX stock logo

Cryoport, Inc., a life sciences services company, provides temperature-controlled logistics solutions in the Americas, Europe, the Middle East, Africa, and the Asia Pacific. The company offers Cryoportal, a cloud-based logistics management platform that supports the management of shipments, which in...

Founded: 1990
Full Time Employees: 105
Sector: Industrials
Industry: Integrated Freight & Logistics

Share this website to your friends
• Market Cap:
• Exchange:
• Shs Outstanding:
• Employees:
• Beta:
• Return on Equity (ROE) ttm:
• Return on Assets (ROA) ttm:
• EPS ttm:
• Book value per Share:
• Cash per Share:
• Current ast per Share:
• P/E ttm:
• P/E forward:
• P/E ttm high:
• P/E ttm low:
• P/S ttm:
• P/B ttm:
• P/FCF ttm:
• PEG ratio:
• Cash Ratio ttm:
• Quick Ratio ttm:
• Current Ratio ttm:
• Gross Mgn ttm:
• EBITDA Mgn ttm:
• Operating Mgn ttm:
• Net Income Mgn ttm:
• Trailing Div yield:
• Forward Div yield:
• Payout Ratio ttm:
• Ex-Dividend date:
• Target Price High:
• Target Price Low:
• Target Price Mean:
• Number of Analysts:
• Debt Ratio ttm:
• Debt to Equity ttm:
• Total Net Debt:
At a glance:
Bull Thesis:
Bear Thesis:
Main Competitors:
Moat:
Income Statements:
Quarterly
Annual
    Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 2014-06-30 2014-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31 2010-12-31 2010-09-30 2010-06-30 2010-03-31 2009-12-31 2009-09-30 2009-06-30 2009-03-31 2008-12-31 2008-09-30 2008-06-30 2008-06-27 
                                                                            
      life sciences services revenue
    26,898,000 25,005,000 24,258,000 24,369,000 22,865,000 39,556,000 39,278,000 38,040,000 36,786,000                                                                
      life sciences products revenue
    20,900,000 20,445,000 19,975,000 21,085,000 18,175,000 19,976,000 17,386,000 19,557,000 17,806,000                                                                
      total revenue
    47,798,000 45,450,000 44,233,000 45,454,000 41,040,000 59,532,000 56,664,000 57,597,000 54,592,000                                                                
      yoy
    16.47% -23.65% -21.94% -21.08% -24.82%                                                                    
      qoq
    5.17% 2.75% -2.69% 10.76% -31.06% 5.06% -1.62% 5.50%                                                                 
      cost of services revenue
    13,747,000 12,859,000 12,201,000 12,449,000 11,920,000 21,279,000 21,220,000 21,105,000 21,602,000                                                                
      cost of products revenue
    12,138,000 10,880,000 10,707,000 11,628,000 10,479,000 10,972,000 10,059,000 11,302,000 11,215,000                                                                
      total cost of revenue
    25,885,000 23,739,000 22,908,000 24,077,000 22,399,000 32,251,000 31,279,000 32,407,000 32,817,000                                                                
      gross margin
    21,913,000 21,711,000 21,325,000 21,377,000 18,641,000 27,281,000 25,385,000 25,190,000 21,775,000 23,261,000 24,266,000 24,733,000 27,072,000 26,277,000 26,417,000 28,838,000 22,341,000 23,113,000 23,513,000 25,402,000 24,550,000 19,893,787 6,055,253 5,126,996 5,257,964 4,932,309 4,627,057 4,338,389 3,453,901 2,816,188 2,736,007 2,503,707 2,184,363 1,713,250 1,606,497 1,393,189 1,253,497 796,835 781,950 581,807 384,282 436,313 487,912 370,079 234,537 224,958 339,355 143,150 167,061 72,102 54,642                      
      yoy
    17.55% -20.42% -15.99% -15.14% -14.39% 17.28% 4.61% 1.85% -19.57% -11.48% -8.14% -14.23% 21.18% 13.69% 12.35% 13.53% -9.00% 16.18% 288.31% 395.46% 366.91% 303.34% 30.87% 18.18% 52.23% 75.14% 69.12% 73.28% 58.12% 64.38% 70.31% 79.71% 74.26% 115.01% 105.45% 139.46% 226.19% 82.63% 60.26% 57.21% 63.85% 93.95% 43.78% 158.53% 40.39% 212.00% 521.05%                          
      qoq
    0.93% 1.81% -0.24% 14.68% -31.67% 7.47% 0.77% 15.68% -6.39% -4.14% -1.89% -8.64% 3.03% -0.53% -8.40% 29.08% -3.34% -1.70% -7.44% 3.47% 23.41% 228.54% 18.11% -2.49% 6.60% 6.60% 6.65% 25.61% 22.64% 2.93% 9.28% 14.62% 27.50% 6.65% 15.31% 11.14% 57.31% 1.90% 34.40% 51.40% -11.93% -10.58% 31.84% 57.79% 4.26% -33.71% 137.06% -14.31% 131.70% 31.95%                       
      gross margin %
    45.85% 47.77% 48.21% 47.03% 45.42% 45.83% 44.80% 43.73% 39.89% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN%  
      operating costs and expenses:
                                                                            
      selling, general and administrative
    27,620,000 27,276,000 26,734,000 26,908,000 24,191,000 37,057,000 37,654,000 35,963,000 38,304,000 38,814,000 36,023,000 38,802,000 33,241,000 32,635,000 30,235,000 30,563,000 26,622,000 27,586,000 23,901,000 24,688,000 21,388,000                   1,754,875 2,835,372 2,157,771 2,026,357 1,978,091 1,492,732 1,510,708 1,427,850 1,338,170 1,305,562 1,240,413 1,222,074 -3,998,132 1,392,937 1,341,333 1,269,272 1,172,904 1,740,324 1,564,456 1,628,322 1,182,124 1,080,768 1,114,304 943,265          
      engineering and development
    3,907,000 4,466,000 4,523,000 4,118,000 3,934,000 4,155,000 4,157,000 4,646,000 4,752,000 4,749,000 5,152,000 4,263,000 3,876,000 4,677,000 3,985,000 3,522,000 3,538,000 3,890,000 4,188,000 4,462,000 4,304,000 3,493,113 2,311,718 1,946,443 1,732,726 1,069,585 1,640,528 540,933 489,596 598,761 463,361 448,591 329,730 380,315 344,798 230,736 249,843                                    
      total operating costs and expenses
    31,527,000 31,742,000 31,257,000 31,026,000 28,125,000 41,212,000 41,811,000 104,418,000 43,056,000 93,132,000 41,175,000 43,065,000 37,117,000 37,312,000 34,220,000 34,085,000 30,160,000 31,476,000 28,089,000 29,150,000 25,692,000 29,739,678 16,787,690 10,972,437 8,844,195 5,810,660 16,978,807 6,642,787 5,594,447 5,036,053 4,897,267 4,968,892 3,982,668 3,984,425 3,594,617 3,257,083 3,022,810 2,957,667 2,761,205 3,205,925 3,063,137 2,258,067 2,104,081 2,063,096 1,591,784 1,599,987 1,507,094                          
      income from operations
    -9,614,000 -10,031,000 -9,932,000 -9,649,000 -9,484,000 -13,931,000 -16,426,000 -79,228,000 -21,281,000 -69,871,000 -16,909,000 -18,332,000 -10,045,000 -11,035,000 -7,803,000 -5,247,000 -7,819,000 -8,363,000 -4,576,000 -3,748,000 -1,142,000 -9,845,891 -10,732,437 -5,845,441 -3,586,231   -2,304,398 -2,140,546 -2,219,865 -2,161,260 -2,465,185 -1,798,305 -2,271,175 -1,988,120 -1,863,894 -1,769,313 -2,160,832 -1,979,255 -2,624,118 -2,678,855 -1,821,754 -1,616,169 -1,693,017 -1,357,247 -1,375,029 -1,167,739 -1,274,562 -1,256,991 -1,286,747 -1,260,075 4,637,055 -1,549,003 -1,553,832 -1,540,543 -1,471,125 -2,061,474 -1,941,998 -1,960,081 -1,463,245 -1,342,742 -1,482,626 -1,308,461 2,879,539 -891,180 -1,041,048 -951,508 -684,835 -720,958 -1,014,115 -775,785  
      yoy
    1.37% -28.00% -39.53% -87.82% -55.43% -80.06% -2.86% 332.18% 111.86% 533.18% 116.70% 249.38% 28.47% 31.95% 70.52% 39.99% 584.68% -15.06% -57.36% -35.88% -68.16%   153.66% 67.54%   -6.52% 19.03% -2.26% 8.71% 32.26% 1.64% 5.11% 0.45% -28.97% -33.95% 18.61% 22.47% 55.00% 97.37% 32.49% 38.40% 32.83% 7.98% 6.86% -7.33% -127.49% -18.85% -17.19% -18.21% -415.20% -24.86% -19.99% -21.40% 0.54% 53.53% 30.98% 49.80% -150.82% 50.67% 42.42% 37.51% -520.47% 23.61% 2.66% 22.65%      
      qoq
    -4.16% 1.00% 2.93% 1.74% -31.92% -15.19% -79.27% 272.29% -69.54% 313.22% -7.76% 82.50% -8.97% 41.42% 48.71% -32.89% -6.50% 82.76% 22.09% 228.20% -88.40% -8.26% 83.60% 63.00%    7.65% -3.57% 2.71% -12.33% 37.08% -20.82% 14.24% 6.66% 5.35% -18.12% 9.17% -24.57% -2.04% 47.05% 12.72% -4.54% 24.74% -1.29% 17.75% -8.38% 1.40% -2.31% 2.12% -127.17% -399.36% -0.31% 0.86% 4.72% -28.64% 6.15% -0.92% 33.95% 8.97% -9.43% 13.31% -145.44% -423.12% -14.40% 9.41% 38.94% -5.01% -28.91% 30.72%   
      operating margin %
    -20.11% -22.07% -22.45% -21.23% -23.11% -23.40% -28.99% -137.56% -38.98% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% NaN% NaN% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity%  
      other income:
                                                                            
      investment income
    3,090,000 3,357,000 3,402,000 1,466,000 1,573,000 1,427,000 3,059,000 2,809,000 2,600,000 2,615,000 2,848,000 2,647,000 2,467,000 2,677,000 2,485,000 2,048,000 1,264,000 1,635,000 851,000 368,000 398,000                                                    
      interest expense
    -432,000 -634,000 -526,000 -618,000 -583,000 -636,000 -889,000 -1,245,000 -1,338,000 -1,306,000 -1,357,000 -1,331,000 -1,509,000 -1,456,000 -1,609,000 -1,586,000 -1,491,000 -1,126,000 -1,189,000 -1,164,000 -1,210,000 -1,077,751 -1,081,542 -398,256 -2,451   -333,910 -338,728       -26 -15,667 -19,305 -21,242 -81,194 -79,946 -601,002 -303,800 -242,678 -48,605 -7,854 -1,128,878 -157,673 -31,786 -512,776 -82,219 48,183 -11,896 -11,759 -24,599 -207,711 -78,974 -107,757 -133,311 -171,177 -151,428 -157,452 -138,708 5,305,564 -1,169,337 -1,610,059 -1,820,198 -740,168 -739,347 -658,099 -555,769  
      other expense
    -2,368,000               -4,028,000 -5,017,000    -535,000                 -1,453 -1,915 -4,872 -1,347 -2,707  -1,437 -1,906 -1,876                           
      total other income
    290,000 2,636,000 3,401,000 -2,091,000 690,000 -4,717,000 17,880,000 1,622,000 2,601,000 6,123,000 4,111,000 612,000 4,963,000                                     -13,672,901    2,730      -39,958 -113,894  -18,743    1,314,784      
      loss from continuing operations before provision for income taxes
    -9,324,000   -11,740,000 -8,794,000                                                                    
      provision for income taxes
    -108,000 -1,126,000 -165,000 -274,000 -234,000 -29,000 -649,000 -383,000 -215,000 1,359,000 -471,000 -635,000 -492,000 -190,500 -57,000 -364,000 -341,000   -499,000 -1,038,000   -49,833    -9,624  -4,214 -2,102 -12,825 -813 -912   -4,231 -2,878 -2,484  -305  -3,320    -1,600                          
      loss from continuing operations
    -9,432,000   -12,014,000 -9,028,000                                                                    
      loss from discontinued operations
    -1,112,000    -2,953,000                                                                    
      net income
    -10,544,000 -11,644,000 -6,943,000 105,180,000 -11,981,000 -18,677,000 805,000 -77,989,000 -18,895,000 -62,389,000 -13,269,000 -18,355,000 -5,574,000 -9,436,000 -5,316,000 -9,177,000 -13,404,000 -260,086,000 -6,526,000 -5,389,000 -3,527,000 -11,529,540 -11,417,821 -5,802,746 -3,942,893   -2,528,491 -2,386,902 -2,258,264 -2,143,687 -2,470,890 -2,682,760 -2,269,669 -1,979,664 -1,860,457 -1,789,211 -2,184,468 -3,934,714 -2,710,184 -2,760,453 -2,425,463 -1,924,264 -1,937,132 -1,407,758 -1,384,759 -2,297,264 -1,441,910 -1,840,331 -14,959,648 -1,323,537 4,659,140 -1,567,011 -1,552,702 -1,545,807 -1,669,399 -2,079,565 -2,030,110 -2,053,854 -1,857,017 -1,456,636 -1,509,821 -1,328,804 5,079,724 2,450,669 -7,186,322 363,276 -5,459,296 -1,454,081 -1,569,293 -8,222,481  
      yoy
    -11.99% -37.66% -962.48% -234.87% -36.59% -70.06% -106.07% 324.89% 238.98% 561.18% 149.60% 100.01% -58.42% -96.37% -18.54% 70.29% 280.04% 2155.82% -42.84% -7.13% -10.55%   129.49% 65.19%   2.33% -11.03% -0.50% 8.29% 32.81% 49.94% 3.90% -49.69% -31.35% -35.18% -9.94% 104.48% 39.91% 96.09% 75.15% -16.24% 34.34% -23.51% -90.74% 73.57% -130.95% 17.44% 863.46% -14.38% -379.09% -24.65% -23.52% -24.74% -10.10% 42.76% 34.46% 54.56% -136.56% -159.44% -78.99% -465.78% -193.05% -268.54% 357.93% -104.42%      
      qoq
    -9.45% 67.71% -106.60% -977.89% -35.85% -2420.12% -101.03% 312.75% -69.71% 370.19% -27.71% 229.30% -40.93% 77.50% -42.07% -31.54% -94.85% 3885.38% 21.10% 52.79% -69.41% 0.98% 96.77% 47.17%    5.93% 5.70% 5.34% -13.24% -7.90% 18.20% 14.65% 6.41% 3.98% -18.09% -44.48% 45.18% -1.82% 13.81% 26.05% -0.66% 37.60% 1.66% -39.72% 59.32% -21.65% -87.70% 1030.28% -128.41% -397.33% 0.92% 0.45% -7.40% -19.72% 2.44% -1.16% 10.60% 27.49% -3.52% 13.62% -126.16% 107.28% -134.10% -2078.20% -106.65% 275.45% -7.34% -80.91%   
      net income margin %
    -22.06% -25.62% -15.70% 231.40% -29.19% -31.37% 1.42% -135.40% -34.61% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% NaN% NaN% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% Infinity% Infinity% -Infinity% Infinity% -Infinity% -Infinity% -Infinity% -Infinity%  
      paid-in-kind dividend on series c convertible preferred stock
    -2,000,000 -2,000,000 -2,000,000 -2,000,000 -2,000,000 -2,000,000 -2,000,000 -2,000,000 -2,000,000 -2,000,000 -2,000,000 -2,000,000  -2,000,000 -2,000,000 -2,000,000  -2,000,000 -2,000,000 -2,000,000 -2,196,000                                                    
      net loss attributable to common stockholders
    -12,544,000    -13,981,000 -20,677,000 -1,195,000 -79,989,000 -20,895,000 -64,389,000 -15,269,000 -20,355,000 -7,574,000 -11,436,000 -7,316,000 -11,177,000 -15,404,000 -262,086,000 -8,526,000 -7,389,000 -5,723,000             -2,269,669 -1,979,664 -1,860,457 -1,789,211 -2,184,468 -3,934,714 -2,785,644 -2,999,842 -2,664,851 -6,607,102 -3,950,128 -1,995,972 -3,183,660 -3,066,773                          
      net income per share
    -0.23 -0.21 -0.17 2.33 -0.28 -0.42 -0.02 -1.62 -0.43 -1.32 -0.31 -0.42 -0.16 -0.24 -0.15 -0.23 -0.31 -5.7 -0.18 -0.16 -0.13 -1.39 -0.29 -0.15 -0.11   -0.08 -0.08 -0.08 -0.07 -0.09 -0.1 -0.09 -0.08 -0.08 -0.1 -0.14 -0.28 -0.09 -0.42 -0.41 -1.31 -2.3 -0.03 -0.05                           
      weighted-average common shares issued and outstanding — basic and diluted
    49,897,817 50,071,665 50,125,268 50,257,112                                                                     
      impairment loss
           63,809,000                                                                 
      gain on extinguishment of debt
          17,326,000 1,179,000  1,419,750 5,679,000                                                              
      other income
     -87,000 525,000 -2,939,000 -300,000 -5,508,000 -1,616,000 -1,121,000 1,339,000 4,814,000 -3,059,000 -704,000 4,005,000 1,855,000 1,668,000   -1,354,000 -588,000 -346,000  -1,465,691 367,093 490,784 -321,186 427,653 133,499 119,441 91,472 35,068 19,675 7,120 15,768 2,418 8,456 3,463       -975    953                          
      income from continuing operations before provision for income taxes
     -6,193,750 -6,531,000                                                                      
      income from continuing operations
     -6,362,000 -6,696,000                                                                      
      income from discontinued operations
     -3,123,000 -247,000 117,194,000                                                                     
      net income attributable to common stockholders
     -13,644,000 -8,943,000 103,180,000                                                                     
      loss from continuing operations — basic and diluted
       -280                                                                     
      loss per share from continuing operations - basic and diluted
        -0.22                                                                    
      loss per share from discontinued operations - basic and diluted
        -0.06                                                                    
      weighted-average common shares issued and outstanding - basic and diluted
        49,947,012                                                                    
      income before provision for income taxes
         -18,648,000 1,454,000 -77,606,000 -18,680,000 -63,748,000 -12,798,000 -17,720,000 -5,082,000 -7,959,000 -5,259,000 -8,813,000 -13,063,000 -260,962,000 -5,502,000 -4,890,000 -2,489,000 -11,628,333 -11,446,886 -5,752,913 -3,909,868   -2,518,867  -2,254,050 -2,141,585 -2,458,065 -2,681,947 -2,268,757 -1,979,664 -1,860,457 -1,784,980 -2,181,590 -3,932,230 -2,710,184 -2,760,148 -2,425,463 -1,920,944 -1,937,132 -1,407,758 -1,384,759 -2,295,664                          
      weighted-average shares outstanding – basic and diluted
         49,349,624 49,417,757 49,345,644 49,019,964 48,737,377 48,904,102 48,709,384   48,520,696 48,792,559   46,137,147    39,144,916 38,281,087 37,548,549  35,674,162 31,176,166 30,441,996  28,769,867 27,808,873 26,774,179  24,632,169 23,965,825 17,604,283 15,120,479 14,199,742  7,225,006 6,505,016 5,055,649 5,006,219 60,057,846 60,048,933 59,989,321 48,850,513                         
      ​
                                                                            
      service revenues
             37,025,000 36,022,000 35,204,000 35,836,000 33,088,000 33,296,000 34,585,000 32,910,000 31,723,000 30,899,000 29,679,000 26,765,000                                                    
      product revenues
             20,235,000 20,135,000 21,817,000 26,981,000 27,270,000 27,168,000 29,568,000 19,392,000 24,717,000 25,794,000 26,512,000 26,519,000                                                    
      total revenues
             57,260,000 56,157,000 57,021,000 62,817,000 60,358,000 60,464,000 64,153,000 52,302,000 56,440,000 56,693,000 56,191,000 53,284,000                                                    
      cost of service revenues
             21,933,000 20,803,000 20,008,000 19,076,000 18,445,000 18,913,000 19,111,000 18,718,000 18,888,000 18,114,000 16,742,000 15,552,000                                                    
      cost of product revenues
             12,066,000 11,088,000 12,280,000 16,669,000 15,636,000 15,134,000 16,204,000 11,243,000 14,439,000 15,066,000 14,047,000 13,182,000                                                    
      total cost of revenues
             33,999,000 31,891,000 32,288,000 35,745,000 34,081,000 34,047,000 35,315,000 29,961,000 33,327,000 33,180,000 30,789,000 28,734,000                                                    
      paid in kind dividend on series c convertible preferred stock
                -2,000,000    -2,000,000                                                        
      weighted-average common shares outstanding – basic and diluted
                48,362,501 48,987,295   49,660,579 45,927,591  45,757,532 43,804,483 38,582,432    33,394,285    28,210,648    22,963,382      7,339,855                                 
      total other expense
                 3,076,000 2,544,000 -3,566,000 -5,244,000 -252,599,000 -926,000 -1,142,000 -1,347,000                           -3,579,925.75 -583,340  -63,462 -5,135.75 -18,008  -5,264 -198,274 -18,091 -88,112 -92,173   -27,195  -550,010 3,341,849 -6,143,674  -4,773,661 -733,123 -555,178 -7,445,896  
      benefit from income taxes
                     876,000 -1,024,000                                                      
      revenues
                         7,583,791.25 11,172,084 9,389,006 9,774,075 9,242,066 9,583,334 8,463,588 6,652,912 5,690,898 5,285,355 4,627,011 4,023,189 3,322,000 3,002,655 2,917,378 2,712,234 1,976,826 1,917,566 1,555,545 1,458,563 1,437,028 1,431,063 1,198,544 975,188 825,000 936,588             100,066 99,569 124,409 151,460 -42,770 20,707 8,478       
      cost of revenues
                         3,473,738 5,116,831 4,262,010 4,516,111 4,309,757 4,956,277 4,125,199 3,199,011 2,874,710 2,549,348 2,123,304 1,838,826 1,608,750 1,396,158 1,524,189 1,458,737 1,179,991 1,135,616 973,738 1,074,281 1,000,715 943,151 828,465 740,651 600,042 597,233 691,676 590,266 507,725 433,321 -1,065,265 368,795 344,440 353,618 329,928 344,702 363,550 354,280 273,713 256,523 378,217 394,535 -458,144 132,418 177,267       
      general and administrative
                         5,139,325.25 10,794,110 5,733,149 4,030,042 2,132,865 9,376,686 3,258,781 2,696,859 2,447,962 2,613,476 2,668,845 2,068,510 2,031,446 1,896,845 1,789,514 1,703,032 1,507,634 1,429,768                                  
      sales and marketing
                         2,514,033.5 3,681,862 3,292,845 3,081,427 2,608,210 5,961,593 2,843,073 2,407,992 1,989,330 1,820,430 1,851,456 1,584,428 1,572,664 1,352,974 1,236,833 1,069,935 1,235,353 1,195,638                                  
      benefit for income taxes
                         -13,448.25 29,065  -33,025    900                                            
      warrant inducement and repricing expense
                                    -899,410                                        
      loss before benefit for income taxes
                                -2,387,802                                            
      warrant repricing expense
                                          -1,929,818                                  
      undeclared cumulative preferred dividends
                                           -75,460 -239,389 -239,388 -208,490 -110,427 -95,304 -71,874 -27,723                          
      other expense:
                                                                            
      research and development
                                         214,680 135,799 144,478 227,765 100,296 77,724 85,005 99,052 89,279 79,244 79,542 118,490 118,436 92,643 -304,606 94,424 101,656 108,952 145,212 120,702 124,705 101,230 107,474 105,020 114,514 122,121          
      preferred stock beneficial conversion charge
                                              -4,474,348 -1,902,569 -492,910 -1,727,027 -741,786                          
      debt conversion expense
                                                    -552,750 -13,161,017                       
      change in fair value of derivatives
                                                                            
      net loss attributable to common stockholders – basic and diluted
                                                  -0.05                          
      net revenues
                                                   456,279.25 757,327 579,827 487,963 183,012.25 307,153 233,597 191,299 94,679.5 144,254 110,713 123,751              
      operating expenses:
                                                                            
      total operating expenses
                                                   1,024,404.5 1,424,052 1,358,849 1,314,717 -4,302,738 1,487,361 1,442,989 1,378,224 1,318,116 1,861,026 1,689,161 1,729,552 1,289,598 1,185,788   -2,464,165 779,469 872,259 816,034 564,728 563,962 885,144 670,831  
      change in fair value of derivative liabilities
                                                   5,211.25 1,196 892 18,757 -27,696 -6,112 14,489 19,335 10,010 60,185 14,685 34,283 -227,270 33,987 126,345 116,528 -3,101,225 4,508,352 -4,535,848 3,134,298      
      income before income taxes
                                                   -4,530,879 -1,840,331 -14,959,648 -1,323,537 -1,165,980.5 -1,567,011 -1,551,102 -1,545,807 -1,540,482.25 -2,079,565 -2,030,110 -2,052,254 -1,857,017 -1,456,636 -1,509,821 -1,327,204   -7,184,722 363,276 -5,458,496 -1,454,081 -1,569,293 -8,221,681  
      income taxes
                                                       -1,598  1,600  400   1,600    1,600 -1,598  1,600  800   800  
      net loss per common share, basic and diluted
                                                   -0.1 -0.03 -0.38 -0.03 -0.05 -0.04 -0.04 -0.04 -0.05 -0.07 -0.07 -0.07   -0.15 -0.16          
      basic and diluted weighted-average common shares outstanding
                                                    58,995,821 39,110,774 38,062,826  37,760,628 37,760,628 37,760,628 28,974,843 28,246,661 27,967,380 27,690,408 13,301,769  10,268,637 8,146,477     41,238,185 41,208,555 41,167,472 41,018,074  
      gross loss
                                                       334,317 -61,642 -110,843 -162,319 -153,009 -200,448 -252,837 -230,529 -173,647 -156,954 -253,808 -243,075 415,374 -111,711 -168,789 -135,474 -120,107 -156,996 -128,971 -104,954  
      interest income
                                                           -573 698 4,960 6,855 4,675 3,547 3,912 3,437 -6,540 2,834 2,233 1,481 1,866 6,224 11,194 12,814  
      loss on sale of property and equipment
                                                                            
      net income per common share:
                                                                            
      basic
                                                               -0.1 -0.11   -0.275 0.5  0.01      
      diluted
                                                               -0.1 -0.11   -0.275 0.26  0.01      
      weighted-average common shares outstanding:
                                                                            
      basic
                                                                13,564,985      42,939,649      
      diluted
                                                                13,564,985      46,563,395      
      costs and expenses:
                                                                            
      total costs and expenses
                                                                 1,228,818 1,065,386          
      selling, general and administrative expenses
                                                                   549,386.25 690,043 779,193 728,309 496,886 550,670 779,691 560,040  
      research and development expenses
                                                                   67,554.25 89,426 93,066 87,725 67,842 13,292 105,453 110,791  
      loss on sale of fixed assets
                                                                   788   -797      
      loss on extinguishment of debt
                                                                       -4,035,359   -6,902,941  
      income (loss) before income taxes
                                                                   -1,270,944 2,450,669        
      weighted average common shares outstanding:
                                                                            
      basic
                                                                    4,911,756        
      diluted
                                                                    6,577,322        
      gain (loss) on extinguishment of debt
                                                                         91,727   
      net loss per common share:
                                                                            
      basic and diluted
                                                                     -0.16       
      weighted average common shares outstanding:
                                                                            
      basic and diluted
                                                                     46,154,705       
      net sales
                                                                      13,703 6,511 9,207 5,982 13,424  
      cost of sales
                                                                      149,177 126,618 166,203 134,953 118,378  
      net loss available to common stockholders per common share:
                                                                            
      basic and diluted loss per common share
                                                                       -0.14 -0.04 -0.04 -0.2  
    Balance Sheets:
    Quarterly
    Annual
      Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 2014-06-30 2014-03-31 2013-12-31 2013-09-30 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31 2010-12-31 2010-09-30 2010-06-30 2010-03-31 2009-12-31 2009-09-30 2009-06-30 2009-03-31 2008-12-31 2008-09-30 2008-06-30 2008-06-27 2008-03-31 
                                                                             
        assets
                                                                             
        current assets:
                                                                             
        cash and cash equivalents
      272,912,000 250,494,000 255,811,000 243,416,000 36,102,000 45,289,000 44,665,000 46,458,000 49,663,000 46,346,000 59,473,000 67,314,000 38,538,000 36,595,000 30,724,000 37,034,000 134,448,000 139,101,000 43,680,000 60,357,000 85,494,000 36,873,000 161,987,083 44,326,038 50,622,454 47,234,770 44,585,154 80,642,213 32,771,986 37,327,125 13,849,644 20,011,137 18,993,994 15,042,189 15,397,512 12,854,526 14,532,860 2,558,028 4,525,720 2,792,526 5,247,425 7,059,709 2,385,919 1,405,186 773,922 103,343 170,505 369,581 219,970 532,469 585,107 1,669,634 2,971,567 4,617,535 2,796,089 4,953,454 7,056,604 9,278,443 2,710,976 3,745,745 2,097,202 3,629,886 647,308 1,120,758 556,922 249,758 776,166 1,219,046 2,189,698 2,231,031 2,231,031 
        short-term investments
      130,722,000 160,714,000 165,503,000 182,559,000 207,929,000 216,460,000 228,001,000 380,684,000 398,881,000 410,409,000 406,389,000 437,360,000 484,076,000 486,728,000 498,801,000 513,584,000 465,063,000 489,698,000 305,802,000 289,056,000 267,721,000 56,444,000 40,952,522 163,891,831 46,809,959 47,060,786 48,917,336 14,103,653 14,500,748 9,930,968 9,884,918                                         
        accounts receivable
      39,004,000 33,359,000 34,914,000 33,409,000 28,371,000 45,778,000 43,461,000 40,160,000 41,253,000 42,074,000 42,626,000 43,076,000 45,574,000 43,858,000 44,419,000 43,903,000 35,837,000 39,412,000 38,460,000 38,102,000 36,504,000 31,377,000 7,783,502 7,038,733 6,139,538 7,098,191 7,497,190 6,095,858 4,208,333 3,543,666 3,197,224 3,618,929 2,385,904 1,625,476 1,464,136 1,250,731 1,467,849 1,000,226 1,015,265 1,020,999 616,785 702,908 757,436 589,699 407,459 408,080 492,865 515,825 635,687 387,669 201,137 170,368 144,766 146,124 83,708 111,387 75,945 55,794 35,924 58,940 32,816 81,036 10,030 7,273 7,555 2,546 4,822 4,473 2,051 21,411 21,411 
        inventories
      21,750,000 23,188,000 23,326,000 23,035,000 23,340,000 22,470,000 23,552,000 23,609,000 25,020,000 26,206,000 29,104,000 28,821,000 26,487,000 27,678,000 24,542,000 23,070,000 22,062,000 16,501,000 13,484,000 11,665,000 11,544,000 10,535,000 476,622 538,376 464,588 473,961 350,920 306,438 227,090 220,514 130,299 97,290 121,926 114,796 90,254 72,621 70,960 82,191 83,544 69,801 52,880 79,230 104,804 69,680 66,958 58,804 38,601 29,703 30,008 43,305 55,459 55,919 47,506 51,754 47,130 42,679 44,963 44,224 59,863 60,228     512,556 530,241 533,204 421,345 195,036 121,952 121,952 
        prepaid expenses and other current assets
      6,147,000 8,419,000 5,289,000 7,071,000 7,444,000 11,574,000 10,658,000 11,075,000 10,887,000 10,077,000 11,548,000 8,616,000 9,959,000 9,317,000 10,639,000 8,250,000 8,363,000 8,804,000 8,958,000 12,574,000 18,485,000 11,928,000 1,444,303 891,652 1,002,189 1,096,855 872,436 526,648 741,614 752,269 882,141 502,617 541,462 516,427 264,343 308,929 321,419 606,823 288,955 248,729                       147,837 140,778 166,749 170,399 128,960 126,404 154,940 153,016 153,016 
        total current assets
      470,535,000 476,174,000 484,843,000 489,490,000 411,276,000 341,571,000 350,337,000 501,986,000 525,704,000 535,112,000 549,140,000 585,187,000 604,634,000 604,176,000 609,125,000 625,841,000 665,773,000 693,516,000 410,384,000 411,754,000 419,748,000 147,157,000 212,644,032 216,686,630 105,038,728 102,964,563 102,223,036 101,674,810 52,449,771 51,774,542 27,944,226 24,229,973 22,043,286 17,298,888 17,216,245 14,486,807 16,393,088 4,247,268 5,913,484 4,132,055 6,206,055 8,030,520 3,511,386 2,161,902 1,370,752 655,539 783,392 1,111,614 988,383 1,004,128 898,733 1,934,551 3,201,424 5,132,751 3,061,571 5,358,839 7,656,734 9,997,675 3,111,090 4,328,242 2,322,747 3,905,340 895,205 1,370,924 1,345,432 1,053,997 1,543,629 1,979,464 2,747,645 2,731,080 2,731,080 
        property and equipment
      89,805,000 85,448,000 83,233,000 81,565,000 80,481,000 88,839,000 88,281,000 86,653,000 86,008,000 84,858,000 74,520,000 69,008,000 71,259,000 63,603,000 57,680,000 54,011,000 50,734,000 49,029,000 42,853,000 37,811,000 31,694,000 30,036,000 15,178,619 13,702,732 12,459,703 11,833,057 11,378,987 10,338,007 5,124,655 4,357,498 3,578,494 3,038,618 2,572,298 2,511,174 2,083,467 2,311,680 2,129,397 1,373,207 1,410,349 1,319,741 875,673 767,123 381,362 307,926 349,515 393,372 364,728 408,892 464,122 516,628 524,075 562,873 659,051 682,021 736,447 677,962 658,887 669,580 679,487 696,238 734,996 559,241          
        operating lease right-of-use assets
      39,299,000 39,720,000 40,224,000 38,206,000 39,102,000 47,188,000 30,113,000 29,684,000 31,029,000 32,653,000 32,561,000 30,011,000 30,270,000 26,877,000 24,820,000 22,740,000 17,948,000 20,675,000 18,425,000 17,936,000 15,996,000 14,044,000 8,113,923 5,868,513 6,068,616 4,460,319 4,612,788 4,160,747 1,711,727                                           
        intangible assets
      138,721,000 138,082,000 141,254,000 143,590,000 145,414,000 170,464,000 175,815,000 178,388,000 190,088,000 194,382,000 192,962,000 194,992,000 188,175,000 191,009,000 192,140,000 196,013,000 197,608,000 201,427,000 205,240,000 209,127,000 209,267,000 213,908,000 4,891,124 4,984,012 5,073,182 5,177,578 5,286,690  157,708 137,220 124,822 117,818 105,996 90,646 56,533 29,728 15,199 6,323 4,860 8,581 13,484 118,257 127,327 136,821 146,315 156,407 167,425 180,086 189,094 216,817 294,550 321,698 350,895 379,083 406,320 386,774 356,470 354,854 346,232 346,555 335,894 311,965 244,244 259,616 268,230 264,364 278,519 1,107 1,107 474 474 
        goodwill
      22,137,000 22,400,000 22,409,000 18,713,000 20,960,000 51,660,000 54,057,000 52,384,000 107,588,000 108,403,000 148,954,000 149,308,000 151,616,000 151,117,000 147,458,000 145,201,000 146,591,000 146,954,000 146,371,000 146,974,000 141,305,000 145,282,000 10,999,722 10,999,722 10,999,722 10,999,722 11,149,663 11,149,663                                            
        deposits
      2,046,000 2,092,000 2,097,000 2,096,000 1,997,000 2,902,000 1,493,000 1,668,000 1,674,000 1,680,000 1,656,000 1,210,000 1,218,000 1,017,000 926,000 926,000 944,000 950,000 955,000 947,000 946,000 1,184,000 535,750 534,978 483,300 437,299 406,686 407,369 350,494 350,837 351,844 351,844 363,403 363,403 363,403 363,403 363,403 363,403 363,403 363,403 363,403                               
        deferred tax assets
      1,066,000 1,073,000 268,000 267,000 614,000 868,000 1,669,000 1,578,000 758,000 656,000 863,000 934,000 937,000 947,000 1,642,000                                                         
        total assets
      763,609,000 764,989,000 774,328,000 773,927,000 699,844,000 703,492,000 701,765,000 852,341,000 942,849,000 957,744,000 1,000,656,000 1,030,650,000 1,048,109,000 1,038,746,000 1,033,791,000 1,046,329,000 1,081,332,000 1,112,970,000 824,386,000 825,308,000 819,708,000 552,405,000 252,363,170 252,776,587 140,123,251 135,872,538 135,057,850 133,146,095 59,794,355 56,620,097 31,999,386 27,738,253 25,084,983 20,264,111 19,719,648 17,191,618 18,901,087 5,990,201 7,692,096 5,823,780 7,458,615 8,915,900 4,020,075 2,606,649 1,866,582 1,205,318 1,324,903 1,709,950 1,650,957 1,757,317 1,737,102 2,838,866 4,231,114 6,213,599 4,224,082 6,432,933 8,681,449 11,031,467 4,136,809 5,371,035 3,403,637 4,776,546          
        liabilities and stockholders’ equity
                                                                             
        current liabilities:
                                                                             
        accounts payable and other accrued expenses
      15,937,000 15,283,000 13,884,000 14,756,000 13,442,000 27,208,000 25,194,000 24,805,000 27,376,000 26,995,000 27,875,000 26,124,000 25,860,000 28,046,000 27,441,000 31,086,000 28,309,000 28,583,000 29,235,000 29,336,000 27,083,000 24,844,000 9,663,211 6,509,745 3,171,821 2,498,375 3,130,663 3,416,805 2,326,143 1,709,397 1,885,003 2,210,955 1,345,047 1,259,629 1,141,821 1,369,223 1,656,708 1,184,330 1,366,543 1,271,926 1,109,243 856,000 562,340 758,696 713,465 703,084 538,988 579,678                        
        accrued compensation and related expenses
      17,007,000 12,980,000 10,864,000 9,400,000 12,681,000 13,093,000 11,275,000 10,690,000 14,062,000 11,409,000 10,426,000 8,717,000 10,450,000 8,458,000 8,625,000 8,354,000 12,096,000 9,912,000 8,649,000 6,781,000 8,233,000 7,441,000 2,554,753 1,852,186 2,671,473 1,903,720 1,567,365 1,534,468 1,753,499 1,262,478 884,893 902,919 1,074,532 925,514 628,793 598,325 413,621 368,235 376,844 508,754 377,113 384,643 440,252 725,712 617,636 549,659 502,015 454,288 391,438 342,427 168,465 144,788 128,211 235,996 553,192 409,694 531,413 402,746 253,017 234,570 321,295 312,002          
        deferred revenue
      2,314,000 943,000 1,447,000 1,677,000 1,774,000 1,106,000 1,091,000 1,317,000 1,777,000 1,308,000 1,580,000 927,000 1,009,000 439,000 549,000 818,000 517,000 547,000 308,000 459,000 495,000 445,000 236,975 330,272 341,150 367,867 423,537 221,776 37,918 66,315 15,387 19,106 23,073                                       
        current portion of operating lease liabilities
      3,641,000 4,133,000 4,126,000 3,889,000 3,661,000 5,419,000 5,834,000 5,299,000 5,356,000 5,371,000 4,759,000 4,234,000 4,089,000 3,720,000 3,007,000            562,866 534,586 390,790                                           
        current portion of finance lease liabilities
      419,000 422,000 428,000 427,000 340,000 488,000 470,000 365,000 301,000 286,000 195,000 191,000 114,000 128,000 96,000            24,252 25,940 23,531                                           
        current portion of convertible senior notes, net of discount of 0.8 million and 1.1 million, respectively
      185,390,000                                                                       
        current portion of notes payable
      159,000 163,000   149,000 143,000 153,000 110,000 110,000 149,000 70,000 61,000 61,000 60,000 1,010,000 1,079,000                                                        
        total current liabilities
      224,867,000 219,018,000 30,749,000 30,149,000 74,030,000 64,563,000 61,439,000 59,885,000 48,982,000 45,610,000 44,905,000 40,254,000 41,583,000 40,851,000 40,728,000 44,046,000 44,441,000 42,645,000 41,073,000 38,154,000 37,873,000 35,020,000 13,185,484 9,441,535 7,070,225 5,460,480 5,708,683 5,733,575 4,531,881 3,061,381 2,785,283 3,132,980 2,442,652 2,185,143 1,770,614 1,967,548 2,634,171 2,292,242 2,606,944 2,173,578 2,468,348 2,197,200 1,972,702 2,996,496 2,984,215 2,578,931 2,383,337 4,014,445 1,773,814 1,042,583 952,178 713,087 596,023 1,108,631 2,215,215 2,529,563 3,183,532 3,237,920 2,652,471 2,334,398 1,728,839 1,910,406 20,092,678 24,273,020 16,901,954 4,747,012 3,524,882 3,401,748 2,968,208 1,749,871 1,749,871 
        notes payable, net of current portion
      1,027,000 1,087,000 1,291,000 1,328,000 1,122,000 1,114,000                                                                  
        operating lease liabilities, net of current portion
      39,173,000 39,078,000 39,376,000 37,441,000 38,101,000 44,077,000 26,466,000 26,523,000 27,798,000 29,355,000 29,757,000 27,520,000 27,841,000 24,721,000 23,112,000 21,106,000 15,494,000 18,144,000 16,355,000 17,081,000 14,502,000 12,261,000 7,814,874 5,497,430 5,568,845 4,101,236 4,266,589 3,920,739 1,621,183                                           
        finance lease liabilities, net of current portion
      680,000 741,000 840,000 934,000 758,000 1,245,000 1,306,000 1,137,000 916,000 954,000 632,000 624,000 202,000 216,000 171,000   51,000 64,000 83,000 92,000 112,000 123,654 146,570 149,297 8,539 14,834 18,981 27,138                                           
        deferred tax liabilities
      1,580,000 1,354,000 664,000 985,000 878,000 2,531,000 3,526,000 2,651,000 2,414,000 2,816,000 4,708,000 4,658,000 5,110,000                                                           
        other long-term liabilities
      663,000 444,000 2,708,000 2,567,000 1,353,000 394,000 569,000 427,000 312,000 601,000 484,000 361,000 368,000 451,000 455,000 378,000 372,000 298,000 148,000 176,000 307,000 176,000                                                  
        contingent consideration
      630,000         9,497,000 4,380,000 4,639,000 4,774,000 4,677,000 4,145,000 2,820,000 738,000 729,000 731,000 640,000                                                    
        total liabilities
      268,620,000 262,351,000 261,057,000 258,536,000 301,033,000 301,594,000 283,193,000 452,246,000 470,659,000 468,721,000 463,128,000 486,395,000 487,591,000 482,908,000 478,070,000 477,905,000 471,898,000 471,142,000 177,160,000 177,279,000 172,433,000 169,707,000 132,327,164 126,119,899 12,818,304 9,591,190 24,728,728 24,395,920 20,887,417 18,073,532 2,964,990 3,316,537 2,631,706 2,377,345 1,965,202 2,164,521 2,833,530 2,292,242 2,606,944 2,727,853 2,468,348 2,197,200 1,972,702 3,022,948    4,014,445 3,051,360 2,335,195 2,287,828 2,062,373 1,966,565 2,484,079 3,603,209 3,929,743 4,595,538 5,083,058 5,278,585 5,524,772 5,470,950 5,691,121 21,585,470 25,816,394 18,474,572 6,348,460 5,897,430 5,059,342 4,652,944 3,461,070 3,461,070 
        commitments and contingencies
                                                                             
        stockholders’ equity:
                                                                             
        preferred stock, 0.001 par value...
                                                                             
        class a convertible preferred stock - 0.001 par value...
                                                                             
        class b convertible preferred stock - 0.001 par value...
                                                                             
        class c convertible preferred stock - 0.001 par value...
      44,275,000 42,275,000 40,275,000 38,275,000 36,275,000 34,275,000 32,275,000 30,275,000                                                                
        common stock, 0.001 par value...
      50,000 50,000 50,000 50,000 50,000 50,000 49,000 49,000 49,000 49,000 49,000 49,000 48,000  49,000 49,000 50,000  46,000 46,000 45,000  38,984 38,565 37,930 37,340 35,844 35,486 30,678 30,319 29,213 28,451 27,593 25,702 25,218 23,993 23,938 15,128 15,121 12,251 7,247 7,170 5,066 5,026 60,058 60,058 60,038 59,980 59,247 58,146 37,761 37,761 37,761 37,761 28,283 28,133 27,712 27,505 13,683 12,850 8,150 8,137  47,587 43 41,863 41,303 41,198 41,090 40,929 40,929 
        additional paid-in capital
      1,153,304,000 1,152,680,000 1,152,249,000 1,150,700,000 1,147,380,000 1,145,677,000 1,141,122,000 1,138,263,000 1,135,257,000 1,131,183,000 1,127,335,000 1,123,180,000 1,118,172,000 1,114,896,000 1,086,112,000 1,081,747,000 1,102,725,000 1,100,287,000 846,187,000 841,537,000 837,615,000 566,451,000 300,273,819 295,423,521 290,106,664 285,609,022 268,731,704 254,580,262 182,230,799 179,501,577 167,778,827 160,979,798 156,541,327 149,293,947 146,892,442 142,186,654 141,366,712 122,932,859 122,135,591 116,214,522 114,334,637 113,302,694 106,208,008 97,346,137 92,750,244 90,593,704 87,797,202 83,512,399 82,975,314 81,958,609 64,006,050 63,766,258 63,701,610 63,620,774 58,852,206 58,655,108 58,208,140 58,016,991 49,083,611 48,615,847 45,197,150 45,021,097 25,706,272 24,402,380 23,286,723 25,816,588 21,450,070 21,058,527 20,697,994 13,888,094 13,888,094 
        accumulated deficit
      -699,428,000 -688,884,000 -675,235,000 -668,235,000 -769,156,000 -757,175,000 -738,498,000 -739,303,000 -661,314,000 -642,419,000 -580,030,000 -566,761,000 -548,406,000 -542,832,000 -503,787,000 -498,471,000 -489,294,000 -467,541,000 -207,455,000 -200,929,000 -195,540,000 -192,013,000 -180,483,423 -169,065,602 -163,262,856 -159,319,963 -158,372,424 -145,903,877 -143,375,386 -140,988,484 -138,730,220 -136,586,533 -134,115,643 -131,432,883 -129,163,214 -127,183,550 -125,323,093 -119,250,028 -117,065,560 -113,130,846 -109,352,607 -106,592,154 -104,166,691 -97,768,079 -93,928,378 -92,027,710 -88,915,924 -85,876,874 -84,434,964 -82,594,633 -64,594,537 -63,027,526 -61,474,822 -59,929,015 -58,259,616 -56,180,051 -54,149,941 -52,096,087 -50,239,070 -48,782,434 -47,272,613 -45,943,809 -45,377,624 -47,828,293 -39,928,972 -30,634,355 -25,175,059 -23,720,978 -22,151,685 -13,929,204 -13,929,204 
        accumulated other comprehensive loss
      -3,212,000 -3,483,000 -4,068,000 -5,399,000 -15,738,000 -20,929,000 -16,376,000 -29,189,000 -30,077,000 -26,065,000 -34,101,000 -34,488,000 -29,571,000  -42,928,000 -29,176,000               -43,424                                         
        total stockholders’ equity
      494,989,000 502,638,000 513,271,000 515,391,000 398,811,000 401,898,000 418,572,000 400,095,000 472,190,000 489,023,000 537,528,000 544,255,000 560,518,000 555,838,000 555,721,000 568,424,000 609,434,000 641,828,000 647,226,000 648,029,000 647,275,000 382,698,000 120,036,006 126,656,688 127,304,947 126,281,348 110,329,122 108,750,175 38,906,938 38,546,565 29,034,396 24,421,716 22,453,277 17,886,766 17,754,446 15,027,097 16,067,557 3,697,959 5,085,152 3,095,927 4,990,267 6,718,700 2,047,373         776,493 2,264,549 3,729,520 620,873 2,503,190 4,085,911 5,948,409              
        total liabilities and stockholders’ equity
      763,609,000 764,989,000 774,328,000 773,927,000 699,844,000 703,492,000 701,765,000 852,341,000 942,849,000 957,744,000 1,000,656,000 1,030,650,000 1,048,109,000 1,038,746,000 1,033,791,000 1,046,329,000 1,081,332,000 1,112,970,000 824,386,000 825,308,000 819,708,000 552,405,000 252,363,170 252,776,587 140,123,251 135,872,538 135,057,850 133,146,095 59,794,355 56,620,097 31,999,386 27,738,253 25,084,983 20,264,111 19,719,648 17,191,618 18,901,087 5,990,201 7,692,096 5,823,780 7,458,615 8,915,900 4,020,075         2,838,866 4,231,114 6,213,599 4,224,082 6,432,933 8,681,449 11,031,467              
        current assets held for sale
          108,090,000                                                                   
        long-term assets held for sale
                                                                             
        current portion of convertible senior notes, net of discount of 1.1 million and 0.1 million, respectively
       185,094,000                                                                      
        current portion of contingent consideration
           2,808,000 3,151,000 3,055,000  92,000                                                              
        current liabilities held for sale
          27,657,000                                                                   
        convertible senior notes, net of current portion and discount of 0 and 2.3 million, respectively
                                                                             
        contingent consideration, net of current portion
       629,000 630,000 628,000 580,000 3,751,000 5,021,000 4,700,000 9,779,000                                                               
        long-term liabilities held for sale
                                                                             
        current portion of convertible senior notes, net of discount of 0.1 million
          14,326,000 14,298,000 14,271,000 14,244,000                                                                
        convertible senior notes, net of current portion and discount of 1.4 million and 2.3 million, respectively
        184,799,000                                                                     
        convertible senior notes, net of current portion and discount of 1.7 million and 2.3 million, respectively
         184,504,000                                                                    
        convertible senior notes, net of current portion and discount of 2.0 million and 2.3 million, respectively
          184,211,000                                                                   
        convertible senior notes, net of current portion and discount of 2.3 million and 7.0 million, respectively
           183,919,000                                                                  
        convertible senior notes, net of discount of 2.6 million and 7.0 million, respectively
            183,628,000                                                                 
        notes payable
            1,238,000 1,258,000 1,305,000 1,335,000 307,000 347,000 364,000  351,000 374,000                                                        
        convertible senior notes, net of discount of 5.5 million and 7.0 million, respectively
             355,665,000                                                                
        ​
                                                                             
        convertible senior notes, net of discount of 6.4 million and 7.0 million, respectively
              379,153,000                                                               
        class c convertible preferred stock, 0.001 par value...
              28,275,000 26,275,000 24,275,000 22,275,000 20,275,000 18,275,000 16,275,000 14,275,000 12,275,000 10,275,000 8,275,000 6,275,000 4,275,000 2,844,000                                                  
        convertible senior notes, net of discount of 7.0 million and 10.1 million, respectively
               378,553,000                                                              
        convertible senior notes, net of discount of 7.6 million and 10.1 million, respectively
                377,955,000                                                             
        convertible senior notes, net of discount of 8.9 million and 10.1 million, respectively
                 407,992,000                                                            
        class a convertible preferred stock — 0.001 par value...
                                              455 455 455  443 335 250                         
        class b convertible preferred stock — 0.001 par value...
                                              535 535 535                             
        convertible senior notes, net of discount of 9.5 million and 10.1 million, respectively
                  407,349,000                                                           
        convertible senior notes, net of discount of 10.1 million and 12.7 million, respectively
                   406,708,000                                                          
        notes payable, net of discount of 0 million and 0.05 million, respectively
                   355,000                                                          
        deferred tax liability
                   4,929,000 3,037,000 3,745,000 5,002,000 4,018,000 2,356,000 4,843,000 4,626,000 5,882,000 47,943 56,945 29,937 20,935                                              
        class a convertible preferred stock, 0.001 par value...
                                                 455                            
        class b convertible preferred stock, 0.001 par value...
                                                 162                            
        common stock; 0.001 par value...
                   48,000    50,000    40,000                                                  
        accumulated other comprehensive income
                   -34,549,000   -16,322,000 -1,243,000 173,000 1,100,000 880,000 5,376,000 206,626 260,204 423,209 -45,051 -66,002 38,304 20,847 3,153                                          
        convertible senior notes
                    406,071,000 405,436,000                                                        
        deferred tax asset
                     1,597,000 1,734,000                                                       
        operating lease liabilities
                     2,656,000 3,466,000 3,542,000 2,820,000 1,523,000 2,002,000 2,231,000 666,929 691,386 813,574 665,901                                              
        other liabilities
                     53,000 53,000                                                       
        convertible senior notes, net of discount of 12.0 million and 12.7 million, respectively
                      404,803,000                                                       
        note payable, net of discount of 0.03 million and 0.05 million, respectively
                      1,048,000                                                       
        other long-term assets
                       419,000 158,000 759,000 752,000 794,000                                                  
        finance lease liabilities
                       61,000 61,000 55,000 60,000 59,000 63,616 57,946 72,207 24,617                                              
        convertible senior notes, net of discount of 12.7 million and 3.7 million, respectively
                       404,171,000                                                      
        note payable, net of discount of 0.05 million and 0 million, respectively
                       1,086,000                                                      
        convertible senior notes, net of discount of 3.1 million and 3.7 million, respectively
                        111,924,000                                                     
        note payable, net of discount of 0.1 million and 0, respectively
                        4,509,000                                                     
        convertible senior notes, net of discount of 3.3 million and 3.7 million, respectively
                         111,729,000                                                    
        note payable, net of discount of 0.2 million and 0, respectively
                         4,573,000                                                    
        convertible senior notes, net of discount of 3.5 million and 3.7 million, respectively
                          111,536,000                                                   
        note payable, net of discount of 1.2 million and 0, respectively
                          3,497,000                                                   
        convertible senior notes, net of discount of 3.7 million
                           111,344,000                                                  
        note payable
                           4,912,000                                                  
        convertible senior notes, net of discount of 3.8 million
                            111,155,209                                                 
        convertible senior notes, net of discount of 4.0 million
                             110,977,419                                                
        revenues
                              9,774,075 33,941,900  8,463,588              1,437,028                              
        cost of revenues
                              4,516,111 16,590,244  4,125,199              1,000,715                              
        gross margin
                              5,257,964 17,351,656  4,338,389              436,313                              
        operating costs and expenses:
                                                                             
        general and administrative
                              4,030,042 17,465,191  3,258,781                                            
        sales and marketing
                              3,081,427 13,820,868  2,843,073                                            
        engineering and development
                              1,732,726 3,740,642  540,933                                            
        total operating costs and expenses
                              8,844,195 35,026,701  6,642,787              2,258,067                              
        income from operations
                              -3,586,231 -17,675,045  -2,304,398              -1,821,754                              
        other income:
                                                                             
        interest expense
                              -2,451 -1,366,924  -333,910              -601,002                              
        other income
                              -321,186 772,065  119,441              -2,707                              
        income before benefit from income taxes
                              -3,909,868 -18,269,904  -2,518,867              -2,425,463                              
        benefit for income taxes
                              -33,025                                               
        net income
                              -3,942,893 -18,331,479  -2,528,491              -2,425,463                              
        net income per share
                              -0.11 -0.55  -0.08              -0.41                              
        weighted-average shares outstanding – basic and diluted
                              37,548,549   31,176,166              6,505,016                              
        convertible note, net of discount of 288,400 as of december 31, 2018
                                                                             
        deferred rent liability, net of current portion
                                   267,415                                          
        warrant inducement and repricing expense
                                                                             
        total other income
                               -594,859                                              
        benefit from income taxes
                               -61,575  -9,624                                            
        weighted-average common shares outstanding – basic and diluted
                               33,394,285                                              
        convertible note, net of discount of 261,378 and 288,400, respectively
                                14,738,622                                             
        3
                                                                             
        other intangible assets
                                 5,415,499                                            
        convertible note, net of discount of 277,375 and 288,400, respectively
                                 14,722,625                                            
        convertible note, net of discount of 292,800 and 288,400, respectively
                                  14,707,215                                           
        capital lease obligations
                                   23,191                                          
        convertible note, net of discount of 288,400
                                   14,711,580                                          
        capital lease obligations, net of current portion
                                   33,156                                          
        deferred rent liability
                                    179,707 183,557 189,054 192,202 194,588 196,973 199,359                                   
        related-party notes payable and accrued interest, net of discount of 0 and 6,100, respectively
                                          563,842                                   
        related-party notes payable and accrued interest, net of discount of 12,400 and 24,900, respectively
                                           739,677                                  
        related-party notes payable, net of current portion
                                             554,275    26,452                            
        related-party notes payable and accrued interest, net of discount of 18,700 and 24,900, respectively
                                            863,557                                 
        notes payable and accrued interest, net of discount of 221,400 at march 31, 2015
                                                 535,507                            
        related-party notes payable and accrued interest, net of discount of 24,900 and 259,600, respectively
                                             392,898                                
        stockholders’ equity
                                                                             
        other current assets
                                              288,965 188,673 263,227 97,337 122,413 85,312 81,421 196,505 102,718 40,685 57,030 38,630 37,585 65,970 134,644 251,319 387,905 528,045 213,303 63,315 102,099 104,014          
        related-party notes payable and accrued interest, net of discount of 64,000 and 259,600, respectively
                                              981,992                               
        related-party notes payable and accrued interest, net of discount of 129,400 and 259,600, respectively
                                               956,557                              
        selling, general and administrative
                                               2,157,771                              
        research and development
                                               100,296                              
        preferred stock beneficial conversion charge
                                                                             
        undeclared cumulative preferred dividends
                                               -239,388                              
        net income attributable to common stockholders
                                               -2,664,851                              
        related-party notes payable and accrued interest, net of discount of 194,900 and 259,600, respectively
                                                970,110                             
        deposits and other assets
                                                    9,358 9,358 9,358 19,744 19,744 19,744 19,744 19,744 19,744 9,358 9,358 9,358              
        liabilities and stockholders’ deficit
                                                                             
        convertible debentures payable and accrued interest, net of discount of 184,800 at march 31, 2014
                                                                             
        related-party notes payable and accrued interest, net of discount of 259,600 at march 31, 2015
                                                 976,581                            
        stockholders’ (deficit) equity:
                                                                             
        total stockholders’ deficit
                                                 -416,299 -1,117,633 -1,373,613 -1,058,434 -2,304,495 -1,400,403 -577,878         -1,141,776 -153,737 -2,067,313 -914,575 -19,621,336 -23,378,326 -16,598,335 -4,775,904 -3,683,686 -2,621,253 -1,412,601 -181 -181 
        total liabilities and stockholders’ deficit
                                                 2,606,649 1,866,582 1,205,318 1,324,903 1,709,950 1,650,957 1,757,317         4,136,809 5,371,035 3,403,637 4,776,546          
        notes payable and accrued interest, net of discount of 274,500 at december 31, 2014
                                                  343,432                           
        convertible debentures payable and accrued interest, net of discount of 184,750 at march 31, 2014
                                                                             
        related party notes payable and accrued interest
                                                  1,309,682                           
        current portion of related party notes payable
                                                   1,326,188 1,342,334 1,358,120 96,000 96,000 96,000 104,000 96,000 96,000 96,000 96,000 96,000 102,000 140,000 146,000 150,000 150,000 160,000 150,000 150,000 150,000 150,000 150,000 150,000 150,000 150,000 
        convertible debentures payable and accrued interest, net of discount of 184,750 in 2014
                                                     1,622,359                        
        derivative liabilities
                                                      1,199 9,622 3,510 17,999 37,334 47,344 107,529 122,214 156,497 57,503 91,490 217,835 334 13,740,633 18,404,578        
        related party notes payable and accrued interest, net of current portion
                                                      1,277,546 1,292,612 1,335,650 1,349,286 1,370,542 1,375,448 1,387,994 1,400,180 1,412,006 1,423,412 1,441,968 1,451,854 1,463,280 1,478,256 1,492,792 1,506,898 1,520,554  1,546,516 1,558,822 1,570,678   
        accounts payable and accrued expenses
                                                      895,902 602,957 678,091 460,789 353,813 401,399 723,635 563,910 448,658 506,887 407,498             
        convertible debentures payable and accrued interest, net of discount
                                                      390,471                       
        stockholders’ deficit:
                                                                             
        convertible debentures payable and accrued interest
                                                                             
        restricted cash
                                                           251,368   91,317 91,169 91,024 90,858 90,630 90,404 90,030 102,115 101,650 101,053 100,477 208,196 205,920 203,670 203,670 
        liabilities and stockholders’ (deficit) equity
                                                                             
        convertible debentures payable and accrued interest, net of discount of 0 at december 31, 2012 and 8,843 at march 31, 2012
                                                                             
        total stockholders’ (deficit) equity
                                                        -550,726                     
        total liabilities and stockholders’ (deficit) equity
                                                        1,737,102                     
        convertible debentures payable and accrued interest, net of discount of 0 at september 30, 2012 and 8,843 at march 31, 2012
                                                                             
        convertible debentures payable and accrued interest, net of discount of 0 at june 30, 2012 and 8,843 at march 31, 2012
                                                                             
        commitments and contingencies stockholders’ equity:
                                                                             
        current portion of convertible debentures payable and accrued interest, net of discount of 8,843 in 2012 and 197,226 in 2011, respectively
                                                           337,902                  
        line of credit and accrued interest
                                                              90,375 90,388 90,388 90,375 90,375 90,388 90,388 90,310 90,300 90,310 90,334 93,307 103,349 115,943 115,943 
        convertible debentures payable, net of current portion and discount of 0 in 2012 and 8,842 in 2011, respectively
                                                                             
        current portion of convertible debentures payable, net of discount of 35,524 at december 31, 2011 and 197,226 at march 31, 2011, respectively
                                                            795,044                 
        convertible debentures payable, net of current portion and discount of 0 at december 31, 2011 and 8,842 at march 31, 2011, respectively
                                                                             
        current portion of convertible debentures payable, net of discount of 78,138 at september 30, 2011 and 197,226 at march 31, 2011, respectively
                                                             1,352,430                
        convertible debentures payable, net of current portion and discount of 0 at september 30, 2011 and 8,842 at march 31, 2011, respectively
                                                                             
        current portion of convertible debentures payable, net of discount of 135,696 at june 30, 2011 and 197,226 at march 31, 2011, respectively
                                                              1,894,872               
        convertible debentures payable, net of current portion and discount of 0 at june 30, 2011 and 8,842 at march 31, 2011, respectively
                                                                             
        current portion of convertible debentures payable, net of discount of 197,226 in 2011 and 0 in 2010
                                                               1,979,402              
        convertible debentures payable, net of current portion and discount of 8,842 in 2011 and 728,109 in 2010, respectively
                                                               421,726              
        current portion of convertible debentures payable, net of discount
                                                                1,704,065 1,014,420 345,193           
        convertible debentures payable, net of current portion and discount
                                                                1,184,146 1,738,520 2,278,831           
        restricted cash — investor funds
                                                                 255,000            
        deferred financing costs
                                                                 54,156 10,000  233,591 193,773 51,286 3,600 82,550 93,317 104,084 325,769 325,769 
        accounts payable
                                                                 502,543 604,141 823,653 339,436 393,701 321,326 218,433 331,964 248,805 235,859 234,298 234,298 
        deposits from investors
                                                                 255,000            
        inventory
                                                                             
        accrued warranty costs
                                                                      18,743 18,743 24,368 24,368 24,368 29,993 29,993 
        convertible notes payable, net of discount of 13,586 in 2009
                                                                             
        current portion of convertible debentures payable and accrued interest, net of discount of 0 in 2010 and 662,583 in 2009
                                                                   200,000          
        current portion of note payable to former officer
                                                                     96,000 108,000 90,000      
        other accrued expenses
                                                                             
        note payable to former officer and accrued interest, net of current portion
                                                                     36,476 52,064 67,688      
        convertible debentures payable, net of current portion and discount of 728,109 in 2010 and 2,227,205 in 2009, respectively
                                                                   2,302,459          
        fixed assets
                                                                    591,094 613,755 180,922 189,301 204,469 216,341 208,720 193,852 193,852 
        other assets
                                                                      30,367 61,294 104,577 147,860 178,787 209,714 209,714 
        accrued expenses
                                                                    151,363 370,984 90,640 90,547 94,465 94,803 104,446 95,048 95,048 
        accrued salaries and related
                                                                    226,833 244,730 221,108 206,180 197,416 129,878 133,749 138,103 138,103 
        convertible notes payable net of discount of 513,160 (unaudited) at december 31, 2009 and 13,586 at march 31, 2009
                                                                    930,304         
        current portion of convertible notes payable and accrued interest, net of discount of 1,662,177 (unaudited) at december 31, 2009 and 662,583 at march 31, 2009
                                                                    4,319,248         
        current portion of note payable to former officer and accrued interest
                                                                    134,473         
        convertible notes payable, net of current portion and discount of 5,981,425 at december 31, 2009 and 6,681,629 at march 31, 2009
                                                                             
        common stock, 0.01 par value...
                                                                    50,016         
        convertible notes payable and accrued interest, net of discount of 775,960 (unaudited) at september 30, 2009 and 13,586 at march 31, 2009
                                                                     639,647        
        current portion of convertible notes payable and accrued interest, net of discount of 2,468,355 (unaudited) at september 30, 2009 and 662,583 at march 31, 2009
                                                                     3,883,070        
        convertible notes payable, net of current portion and discount of 6,351,425 at september 30, 2009 and 6,681,629 at march 31, 2009
                                                                             
        convertible notes payable and accrued interest, net of discount of 754,486 at june 30, 2009 and 13,586 at march 31, 2009
                                                                      242,552       
        current portion of convertible notes payable and accrued interest, net of discount of 3,514,107 at june 30, 2009 and 662,583 at march 31, 2009
                                                                      1,994,748       
        liability for derivative instruments
                                                                      13,664,537       
        convertible notes payable, net of current portion and discount of 5,968,629 at june 30, 2009 and 6,681,629 at march 31, 2009
                                                                             
        convertible notes payable, net of discount of 13,586
                                                                       46,414      
        current portion of convertible debentures payable and accrued interest, net of discount of 662,583
                                                                       3,836,385      
        current portion of note payable
                                                                           12,000 12,000 
        related party notes and accrued interest payable, net of current portion
                                                                       1,533,760    1,582,084 1,582,084 
        convertible debentures payable, net of current portion of 4,454,424
                                                                             
        current portion of convertible notes payable and accrued interest, net of discount of 229,164 at december 31, 2008 and 1,039,844 at march 31, 2008
                                                                        2,552,335     
        current portion of note payable to officer
                                                                        84,000 72,000 72,000 72,000 72,000 
        convertible notes payable, net of current portion and discount of 3,069,687 at december 31, 2008 and 2,482,513 at march 31, 2008
                                                                        742,746     
        note payable to officer and accrued interest, net of current portion
                                                                        83,286 98,772 114,058   
        current portion of convertible notes payable and accrued interest, net of discount of 907,027 at september 30, 2008 and 1,039,844 at march 31, 2008
                                                                         2,588,587    
        convertible notes payable, net of current portion and discount of 3,073,318 at september 30, 2008 and 2,482,513 at march 31, 2008
                                                                             
        current portion of convertible notes payable and accrued interest, net of discount of 860,886 at june 30, 2008 and 1,039,844 at march 31, 2008
                                                                          2,144,437   
        convertible notes payable, net of current portion and discount of 2,760,796 at june 30, 2008 and 2,482,513 at march 31, 2008
                                                                             
        convertible notes payable and accrued interest, net of discount of 0
                                                                             
        current portion of convertible notes payable and accrued interest, net of discount of 1,039,844
                                                                           902,486 902,486 
        convertible notes payable, net of current portion of 1,936,884
                                                                             
        note payable to officer, net of current portion
                                                                           129,115 129,115 
        note payable, net of current portion
                                                                             
      Cashflow Statements:
      Quarterly
      Annual
        Unit: USD2026-03-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 2014-06-30 2014-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31 2010-12-31 2010-09-30 2010-06-30 2010-03-31 2009-12-31 2009-09-30 2009-06-30 2009-03-31 2008-12-31 2008-09-30 2008-06-30 
                                                                              
          cash flows from operating activities:
                                                                              
          net loss
        -10,544,000   -11,981,000 -18,677,000 805,000 -77,989,000 -18,895,000 -62,389,000   -5,574,000 -9,436,000 -5,316,000 -9,177,000 -13,404,000 -260,086,000 -6,526,000 -5,389,000 -3,527,000 -11,529,540 -11,417,821 -5,802,746 -3,942,893 -947,539 -12,468,547 -2,528,491 -2,386,902 -2,258,264 -2,143,687 -2,470,890 -2,682,760 -2,269,669 -1,979,664 -1,860,457 -1,789,211 -2,184,468 -3,934,714 -2,710,184 -2,760,453 -2,425,463 -1,924,264 -1,937,132 -1,407,758 -1,384,759 -2,297,264 -1,441,910 -1,840,331 -14,959,648 -1,323,537 -1,716,911 -1,567,011 -1,552,704 -1,545,807 -1,669,399 -2,079,565 -2,030,110 -2,053,854 -1,857,017 -1,456,636 -1,509,821 -1,328,804 -566,185 2,450,669   -5,459,296 -1,454,081 -1,569,293 -8,222,481 
          adjustments to reconcile net loss to net cash from operating activities:
                                                                              
          depreciation and amortization
        6,402,000 6,415,000 7,296,000 7,646,000 7,894,000 7,836,000 7,558,000 7,469,000 7,449,000 6,911,000 6,723,000 6,404,000 6,134,000 5,786,000 5,480,000 5,365,000 5,303,000 5,157,000 4,950,000 4,837,000 7,369,913 830,377 844,281 824,429 825,051 792,916 496,690 300,565 264,746 214,000 191,359 187,834 172,851 184,075 176,354 131,551 100,770 97,847 72,904 72,298 48,353 45,673 42,712 50,040 50,046 55,140 53,401 79,199 89,547 89,443 86,697 90,331 121,902 95,029 92,292 88,686 83,160 78,891 69,182 66,599 56,761 52,935 48,605 38,623 31,363 31,502 29,623 21,807 15,923 14,631 
          amortization of debt discount
        296,000 294,000 311,000 320,000 318,000 424,000 597,000 601,000 598,000 645,000 642,000 641,000 651,000 644,000 643,000 643,000 500,000 240,000 232,000 264,000 189,396 187,499   241,630 15,997 15,410 15,383                        8,843 26,681 42,614 57,558 70,372 136,289 135,271 128,916 121,565 1,610,799 1,068,978 2,181,878 1,555,691 583,007 681,523 540,311 418,275 
          non-cash operating lease expense
        1,237,000 1,267,000 2,126,000 1,911,000 1,379,000 1,565,000 1,466,000 1,360,000 1,700,000 1,122,000 1,182,000 1,099,000                                                           
          unrealized loss on investments in equity securities
        1,062,000  46,000 -659,000 2,344,000 -2,471,000 348,000 678,000 -3,563,000   -1,510,000 -1,030,000 3,880,000 3,648,000 4,908,000 1,078,000   263,000 -407,238    13,824                                              
          realized loss on available-for-sale investments
        1,044,000   851,000 102,000 5,957,000 448,000 -2,416,000  -7,000 -17,000 86,000  33,000 31,000 49,000  -8,000 45,000 40,000                                                   
          stock-based compensation expense
        2,395,000 2,526,000 2,375,000 3,700,000 4,413,000 4,838,000 4,997,000 5,456,000 5,848,000 5,976,000 5,800,000 5,184,000 5,333,000 5,366,000 5,258,000 4,125,000 4,182,000 4,148,000 4,025,000 2,990,000 2,561,454 2,432,671 2,301,497 1,620,378 1,610,357 1,945,775 1,991,755 1,413,735  1,498,663 1,445,729 1,049,510  964,857 794,559 770,442 799,797 749,196   637,635 480,377 316,486 210,768 187,358 167,094                         
          loss on disposal of property and equipment
        30,000 44,000 101,000 4,000 89,000 57,000 107,000 131,000 677,000 87,000 113,000 77,000 226,000 270,000 212,000 92,000 417,000 12,000 42,000 71,000 170,108 92,556 40,743 80,593  58,618 52,651 47,603 225,848 109,173 41,861 20,585 109,808 26,382 32,602 17,238 7,249 9,123 131,465 4,430                               
          change in credit losses
        7,000 109,000 79,000 -31,000 -260,000 36,000 -117,000 99,000  -2,000 -30,000 -103,000                                                           
          excess and obsolete inventory
        98,000 146,000 -181,000 145,000         105,000                                                         
          change in contingent consideration
        15,000 -1,000 -23,000 -5,183,000 -518,000 412,000 -2,034,000 293,000 -685,000 -137,000 -114,000 46,000                                                           
          changes in operating assets and liabilities:
                                                                              
          accounts receivable
        -5,733,000 -1,883,000 -6,723,000 778,000 -3,074,000 -2,633,000 1,121,000 437,000 2,585,000 -16,000 2,518,000 -1,414,000 4,170,000 -4,016,000 -7,631,000 3,340,000 -706,000 -974,000 -377,000 -5,213,000 -1,867,710 -774,772 -929,195 954,677 398,999 -1,401,375 -1,929,567 -664,667 -318,907 389,630 -1,268,700 -760,428 -161,350 -223,405 215,482 -272,370 -10,326 -1,691 -406,717 84,160 23,825 -171,077 -184,488 621 78,971 28,309 94,986 -248,018 -29,967 -140,605 -15,960 -30,769 -25,602 1,358 -62,416 27,679 -35,442 -20,151 -19,870 23,016 -26,124 48,220 -71,006 -2,757 282 -5,009 2,276 -349 -2,422 19,360 
          inventories
        1,319,000 -421,000 638,000 -2,305,000 536,000 284,000 1,319,000 1,113,000 3,080,000 -325,000 -2,486,000 1,239,000 -3,025,000 -1,703,000 -1,761,000 -7,715,000 -2,999,000 -1,842,000 -150,000 -988,000 1,324,661 61,754 -73,788 9,373 -123,041 -44,482 -79,348 -6,576 -90,215 -33,009 24,636 -7,130 -24,542 -17,633 -1,661 18,539 1,353 -13,743 -55,197 26,350 -6,500 -35,124 -2,722 -8,154 -20,203 -8,898 305 13,297 9,559 -13,652 16,247 460 -8,413 4,248 -4,624 -4,451 2,284 -739 15,639     63,327 17,685 2,963 -111,859 -226,309 -73,084 
          prepaid expenses and other current assets
        2,223,000 1,333,000 2,794,000 394,000 -2,603,000 1,835,000 -207,000 -1,174,000 2,195,000 -3,549,000 1,522,000 -271,000 -179,000 -376,000 -1,064,000 21,000 334,000 3,234,000 6,033,000 -6,545,000 -7,671,519 -53,684 110,537 94,666 -140,850 -429,138 215,353 10,049    -25,035 -284,065 44,586 12,490 -34,500                                   
          deposits
        16,000 -15,000 -3,000 -167,000 -1,638,000 204,000 -9,000 -11,000 -455,000 1,000 -198,000 -69,000 -18,000   1,000 -20,000 1,000 229,000 -53,549 -772 -51,678 -46,001 -30,613 683                                             
          operating lease liabilities
        -1,212,000 -1,032,000 -1,647,000 -1,288,000 -1,059,000 -1,527,000 -1,452,000 -1,302,000 -1,586,000 -907,000 -1,098,000 -1,004,000                                                           
          accounts payable and other accrued expenses
        -596,000 -129,000 -1,811,000 -783,000 2,946,000 -728,000 -2,558,000 264,000 -2,730,000 2,838,000 402,000 -3,276,000 -3,311,000 1,111,000 -2,176,000 -2,107,000 1,936,000 2,649,000 -5,515,000 532,000 -2,120,123 3,215,353 3,084,458 65,312 -697,790 -444,381 1,053,313 659,335 -223,192 -333,521 856,444 105,343 -77,703 -4,681 -123,881 329,514 72,321 -160,477 -37,317 453,243 144,813 -247,509 54,889 10,381 164,096 -20,228                         
          accrued compensation and related expenses
        4,061,000 1,359,000 -3,201,000 1,633,000 2,044,000 438,000 -3,349,000 2,719,000 871,000 1,765,000 -1,714,000 1,962,000 -351,000 363,000 -3,722,000 2,141,000 1,277,000 1,906,000 -1,465,000 804,000 2,491,967 702,567 -819,287 767,753 336,566 32,897 -219,344 491,123 377,357 -18,026 -171,613 149,018 296,721 30,468 184,704 -5,413 -8,609 -131,910 168,733 10,191 -55,609 -285,460 108,076 67,977 47,644 47,727 62,850 49,011 61,982 63,013 48,967 23,677 16,577 -107,785 -317,196 143,498 -121,719 128,667 149,729 18,447           
          deferred revenue
        1,379,000 -231,000 -180,000 699,000 44,000 -246,000 -439,000 462,000 -299,000 653,000 -82,000 570,000 -110,000 -269,000 -121,000 -30,000 239,000 -151,000 -35,000 49,000 -178,108 -93,297 -10,878 -26,717 -55,734 201,761 -36,433 -28,397                                           
          net deferred tax liability
        236,000 -299,000 1,103,000 -26,000 6,000   -551,000  30,000 -466,000 246,000                                                           
          net cash from operating activities
        3,735,000 2,188,000 -7,345,000 -4,342,000 -5,480,000 447,000 -8,025,000 -3,265,000 2,482,000 -1,959,000 -4,054,000 2,774,000 3,654,000 982,000 -7,011,000 524,000 2,614,000 8,876,000 2,627,000 -5,991,000 -9,713,157 -4,843,235 -1,368,968 1,059,360 741,021 -813,395 -1,061,883 -189,603 -359,406 -664,226 -1,265,095 -1,063,653 -1,220,016 -965,015 -568,172 -829,923 -1,534,360 -1,449,933 -1,969,641 -1,393,693 -1,068,067 -1,874,289 -1,292,409 -1,060,711 -857,533 -917,049 -1,221,253 -841,575 -1,146,840 -1,170,991 -1,106,956 -1,022,319 -1,231,052 -1,424,817 -2,106,672 -1,482,148 -1,644,687 -1,546,627 -1,172,205 -1,406,728 -985,026 -1,247,452 -911,666 -796,196 -639,537 -505,960 -544,008 -458,440 -889,108 -694,914 
          capital expenditures
        -9,981,000 -3,453,000 -4,351,000 -3,168,000 -5,219,000 -4,239,000 -3,790,000 -4,006,000 -11,573,000 -8,969,000 -8,674,000 -9,569,000 -7,857,000 -5,190,000 -4,815,000 -4,245,000 -8,326,000 -8,851,000 -3,894,000 -2,811,000 -3,799,197 -2,576,652 -1,945,992 -596,159 -1,146,898 -1,610,798 -1,457,120 -1,121,025 -1,081,897 -863,049 -699,540 -269,543 -485,260 -207,350 -391,239 -631,082 -67,340 -193,857 -405,258 -378,591 -225,787 -109,615 -2,279  655 -2,045 -6,237 -131,259 -85,035 -24,386 -2,908 -43,871 -18,784 -121,051 -78,329 -44,477 -42,333 -27,988 -60,228 -210,851 
          free cash flows
        -6,246,000 -1,265,000 -11,696,000 -7,510,000 -10,699,000 -3,792,000 -11,815,000 -7,271,000 -9,091,000 -10,928,000 -12,728,000 -6,795,000 -4,203,000 -4,208,000 -11,826,000 -3,721,000 -5,712,000 25,000 -1,267,000 -8,802,000 -13,512,354 -7,419,887 -3,314,960 463,201 -405,877 -2,424,193 -2,519,003 -1,310,628 -1,441,303 -1,527,275 -1,964,635 -1,333,196 -1,705,276 -1,172,365 -959,411 -1,461,005 -1,601,700 -1,643,790 -2,374,899 -1,772,284 -1,293,854 -1,983,904 -1,294,688 -1,060,711 -857,533  -1,220,598 -843,620 -1,153,077 -1,302,250 -1,191,991 -1,046,705 -1,233,960 -1,468,688 -2,125,456 -1,603,199 -1,723,016 -1,591,104 -1,214,538 -1,434,716 -1,045,254 -1,458,303 -911,666 -796,196 -639,537 -505,960 -544,008 -458,440 -889,108 -694,914 
          cash flows from investing activities:
                                                                              
          purchases of property and equipment
        -9,981,000 -3,453,000 -4,351,000 -3,168,000 -5,219,000 -4,239,000 -3,790,000 -4,006,000 -11,573,000 -8,969,000 -8,674,000 -9,569,000 -7,857,000 -5,190,000 -4,815,000 -4,245,000 -8,326,000 -8,851,000 -3,894,000 -2,811,000 -3,799,197 -2,576,652 -1,945,992 -596,159 -1,146,898 -1,610,798 -1,457,120 -1,121,025 -1,081,897 -863,049 -699,540 -269,543 -485,260 -207,350 -391,239 -631,082 -67,340 -193,857 -405,258 -378,591 -225,787 -109,615 -2,279   655 -2,045 -6,237 -131,259 -85,035 -24,386 -2,908 -43,871 -18,784 -121,051 -78,329 -44,477 -42,333 -27,988 -60,228 -210,851         
          software development costs
         -587,000 -1,507,000 -555,000 -125,000 -687,000 -1,631,000 -443,000 -414,000 -2,296,000 -2,071,000 -463,000 -511,000 -401,000 -351,000 -213,000 -113,000 -308,000 -256,000 -193,000                                                   
          sales/maturities of short-term investments
        29,000,000 18,588,000 26,001,000 10,000,000 9,138,000 159,753,000 54,975,000 25,250,000 47,500,000 30,000,000 44,637,000 7,850,000 24,023,000 23,075,000 48,760,000 36,000,000 3,000,000 33,000,000 5,000,000 3,000,000 6,956,756 122,997,378 3,000,000 16,278,866                                               
          patent and trademark costs
        -301,000 -242,000 -343,000 -355,000 -297,000 -163,000 -349,000 -318,000 -255,000 -225,000 -214,000 -177,000 -96,000 -160,000 -220,000 -138,000 -105,000 -41,000 -61,000 -48,000 -83,704 -41,362 -45,080 -29,854 -25,138 -5,441 -22,541 -20,488 -12,398 -7,004 -11,822 -15,350                                       
          net cash from investing activities
        18,718,000 14,306,000 230,039,000 5,922,000 3,479,000 153,570,000 13,321,000 6,445,000 -14,760,000 18,510,000 33,678,000 -1,383,000 7,124,000 -5,865,000 -63,990,000 3,050,000 -195,971,000 -27,008,000 -30,905,000 -215,370,000 -383,059,950 120,338,188 -119,047,756 -542,482 789,874 -36,645,504 -21,419,511 -5,651,974 -1,102,523 -10,785,444 -711,362 -284,893 -519,373 -234,155 -405,768 -641,281 -72,340 -193,857 -405,258 -378,591 -225,787 -109,615 -2,279   655 -2,045 -6,237 -131,259 -107,517 -24,386 -2,908 -43,871 -18,991 -166,717 -132,539 -69,814 -70,904 -49,525 -89,789 -255,232   -6,353 -27,786  54,560 -23,544 -30,132 
          cash flows from financing activities:
                                                                              
          proceeds from exercise of stock options
        229,000 1,023,000 2,947,000 3,000 2,142,000 21,000 9,000 618,000 -2,000 180,000 1,208,000 92,000  999,000                                   100,000                     
          repayment of notes payable
        -35,000 -41,000 -43,000 -37,000 -28,000 -41,000 -36,000 -36,000 -45,000 -15,000 -21,000 10,000  -1,430,000                         -741,377                             
          repayment of finance lease liabilities
        -109,000 -105,000 -165,000 -155,000 -102,000 -162,000 -74,000 -70,000 -79,000 -53,000 -39,000 -31,000 -36,000   -13,000 -16,000 -12,000 -14,000 -18,000 -18,289 -19,470 -17,942 -14,299 -5,930 -5,835 -5,748 -5,678                                           
          net cash from financing activities
        85,000 -2,868,000 -15,864,000 -189,000 2,012,000 -155,291,000 -8,764,000 512,000 -126,000 -24,891,000 1,148,000 71,000 -5,306,000 -459,000 -25,360,000 -8,049,000 288,575,000 2,491,000 1,883,000 271,393,000 266,443,311 2,150,581 114,127,553 2,863,555 1,092,665 1,410,416 70,356,768 1,290,420 24,936,013 5,301,128 2,993,600 5,300,351 1,384,066 3,742,156 -704,394 11,479,535 -360,992 3,376,984 -80,000 -40,000 5,967,644 2,964,637 1,925,952 1,731,290 858,222 717,973 1,370,209 531,121 1,458,016 966,676 1,192,470 -37,822 -67,973 -177,280 3,947,109 -508,500 -325,924 -605,398 7,810,576   -30,000 4,002,863 318,862 1,209,726 840,910 17,999 -39,000 -58,000 683,713 
          effect of exchange rates on cash and cash equivalents
        -120,000 -1,231,000 -10,775,000 681,000 613,000 -519,000 263,000 -375,000 -723,000 499,000 -1,996,000 481,000  -968,000 -1,053,000 -178,000  -1,036,000 1,258,000 -1,411,000  15,511 -7,245 7,251  -8,576 -5,147 -3,982                                           
          net change in cash and cash equivalents
        22,418,000 12,395,000 196,055,000 2,072,000 624,000 -1,793,000 -3,205,000 3,317,000 -13,127,000 -7,841,000 28,776,000 1,943,000 5,871,000 -6,310,000 -97,414,000 -4,653,000 95,421,000 -16,677,000 -25,137,000 48,621,000 -125,114,313 117,661,045 -6,296,416 3,387,684 2,649,616 -36,057,059 47,870,227 -4,555,139 23,477,481 -6,161,493 1,017,143 3,951,805 -355,323 2,542,986 -1,678,334 10,008,331 -1,733,428.498 1,733,194 -2,454,899 -1,812,284 4,673,790 980,733 631,264     -312,499 304,939 -335,574 -22,003 -1,084,527 -1,301,933 -1,645,968 1,821,446 -2,157,365 -2,103,150 -2,221,839 6,567,467 -1,034,769 1,648,543 -1,532,684 2,982,578 -473,450 563,836 307,164 -526,408 -442,880 -970,652 -41,333 
          cash and cash equivalents — beginning of period
        250,494,000 45,289,000 46,346,000 36,595,000  139,101,000  36,873,000  47,234,770  37,327,125  15,042,189 4,524,529 2,792,526  1,405,186  369,581                         
          cash and cash equivalents — end of period
        272,912,000 12,395,000 196,055,000 47,361,000 624,000 -1,793,000 -3,205,000 49,663,000 -13,127,000 -7,841,000 28,776,000 38,538,000  -6,310,000 -97,414,000 134,448,000  -16,677,000 -25,137,000 85,494,000  117,661,045 -6,296,416 50,622,454  -36,057,059 47,870,227 32,771,986  -6,161,493 1,017,143 18,993,994 -355,323 2,542,986 -1,678,334 14,532,860 -1,967,692 4,525,720  -1,812,284 4,673,790 2,385,919  670,579 -67,162 170,505                         
          reconciliation of cash and cash equivalents to the condensed consolidated balance sheets:
                                                                              
          cash and cash equivalents from continuing operations
        250,494,000 34,137,000                                                                   
          cash and cash equivalents from discontinued operations
         11,152,000                                                                   
          total cash and cash equivalents — beginning of period
        250,494,000 45,289,000                                                                   
          total cash and cash equivalents — end of period
        272,912,000 12,395,000 196,055,000 47,361,000                                                                   
          supplemental disclosure of cash flow information:
                                                                              
          cash paid for interest
        28,000 4,000 885,000 36,000 2,064,000 -982,000 1,573,000 38,000 1,607,000 67,000                                                             
          cash paid for income taxes
        502,000 308,000 218,000 408,000 243,000 472,000 290,000 417,000 511,000 -152,000 670,000 433,000                                                           
          supplemental disclosure of non-cash financing activities:
                                                                              
          operating lease right-of-use assets and operating lease liabilities
        947,000 3,292,000 205,000 2,286,000 19,446,000 1,357,000   1,528,000 3,978,000 1,167,000 4,436,000                                                           
          net unrealized gain on available-for-sale debt securities
        18,000 163,000 365,000 808,000 -359,000 1,964,000 994,000 261,000 3,666,000 624,000                                                             
          reclassification of realized gain on available-for-sale debt securities to earnings
        1,096,000 713,000 1,349,000 854,000 -400,000 -7,843,000 3,933,000 -2,314,000 -4,397,000        37,000 28,000 -68,000 30,000 -15,800 -7,752 26,158 394 1,379 8,963 9,748 3,098                                           
          paid-in-kind preferred stock dividend
        2,000,000             2,000,000 2,000,000 2,000,000                                                       
          intangible assets included in property and equipment
        3,633,000                                                                      
          fixed asset purchases included in accounts payable and accrued liabilities
        1,604,000                                                                      
          contingent consideration reclassed to accounts payable and accrued liabilities
         12,000 36,000 833,000                                                                   
          purchase of equipment through finance lease obligation
        57,000 11,000 338,000 39,000                                                                   
          net income
         -3,254,000                                                                363,276     
          adjustments to reconcile net income to net cash from operating activities:
                                                                              
          impairment loss
                                                                            
          unrealized gain on investments in equity securities
                              -192,163 -144,415   -43,803 -31,545                                           
          realized loss on investments in equity securities
                           285,228 11,597 793,175                                               
          gain on extinguishment of debt
            -17,326,000                                                                 
          gain on divested business
         -3,385,000                                                                     
          ​
                                                                              
          purchases of short-term investments
            -799,000 -35,884,000 -14,038,000     -8,435,000 -18,742,000 -106,257,000 -30,354,000 -190,427,000 -50,287,000 -26,675,000 -215,318,000 -22,442,805 -41,176 -120,056,684 -16,195,335 -151,034 -37,024,265 -1,010,199 -5,010,461 -8,228                                          
          proceeds from divested business
                                                                             
          proceeds from related party loans
                                                                              
          acquisitions
                                                                              
          repurchase of common stock
         -3,745,000           -4,611,000 -25,000,000 -8,349,000                                                       
          cash paid for repurchase of 2026 convertible senior notes
                                                                              
          repayment of 2025 convertible senior notes
                                                                             
          paid-in-kind preferred stock dividend, including beneficial conversion feature
         2,000,000 2,000,000 2,000,000 2,000,000 2,000,000 2,000,000 2,000,000 2,000,000 2,000,000 2,000,000 2,000,000                                                           
          fixed assets included in accounts payable and accrued liabilities
         -40,000 80,000 189,000 76,000 -437,000 -78,000 542,000 -130,000 -250,000 115,000 707,000 522,000 84,000 -152,000 549,000 -142,000 -2,314,000 3,670,000 198,000 172,154 -322,568 41,280 608,134 102,402                                              
          realized gain on available-for-sale investments
                             6,940 -5,958 -10,934                                               
          gain on insurance settlement
                -2,642,000                                                          
          insurance proceeds for operations
                1,212,000 3,454,000 118,000 3,311,000 3,000,000                                                       
          insurance proceeds for loss of fixed assets
                976,000 1,000,000 2,000,000                                                       
          cash paid for acquisitions
                                                                              
          cash paid for repurchase of 2026 senior notes
                                                                             
          cash paid to repurchase of 2026 senior notes
             -155,109,000                                                                 
          net deferred tax asset
                                                                              
          goodwill impairment
                                                                              
          realized loss on available-for-sale debt securities
                                                                              
          loss on extinguishment of debt
                                                                          4,035,359 6,804,311.059 6,902.941 
          change in expected credit losses
                                                                              
          net deferred tax (asset) liability
                                                                              
          proceeds from issuance of series c convertible preferred stock, net of issuance costs
                                                                              
          proceeds from public offering, net of offering costs
                                                                              
          proceeds from issuance of convertible senior notes
                                                                            
          purchase of equipment through finance lease obligations
                            484                                                 
          common stock issued for conversion of debt and accrued interest
                                                                              
          receivable included in prepaid expenses and other current assets
                                                                              
          common stock issued for cell&co acquisition
                                                                             
          unrealized (gain) loss on investments in equity securities
                                                                              
          reclassification of realized loss on available-for-sale debt securities to earnings
                  -730,000 99,000  -79,000 33,000                                                       
          net unrealized loss on available-for-sale debt securities
                   -3,675,000                                                           
          provision for bad debt
                    221,000 -22,000 4,000 31,000 -237,000 48,000 152,000 63,000 133,021 30,003 30,000 3,976 43   -27,535 32,075   10 10,000   25,365 7,425 2,503 1,963   2,248                           
          changes in operating assets and liabilities, net of effects of acquisition:
                                                                              
          change in operating lease right-of-use assets and lease liabilities
                    253,000 289,000 22,000 5,000 259,000 83,000 160,000 60,000 72,938 47,577 6,499 6,986 3,238 5,439 -5,668 -9,309                                           
          proceeds from exercise of stock options and warrants
                       313,000 3,009,000 2,503,000 1,897,000 1,586,000 1,076,105 2,418,046 3,015,995 2,877,854 1,078,847 1,412,979 1,555,070 1,315,846 417,952 1,950,823 2,993,600 658,544       10,881 80,978 11,631 146,889                        
          proceeds from issuance of common stock, net of issuance costs
                                                                              
          repayment of note payable
                                                                          -12,000 
          payment of deferred financing costs
                            495 -247,995    -19,748                        -5,822    -27,500 -130,770  -1,897    -73,180 -73,700 -55,590    -191,875 
          effect of exchange rate changes on cash and cash equivalents
                                    3,397                                          
          cash and cash equivalents — beginning of year
                                                                              
          cash and cash equivalents — end of year
                                                                              
          supplemental disclosure of non-cash investing and financing activities:
                                                                              
          contingent consideration
                                                                              
          deferred tax (asset) liability
                     -488,000                                                         
          mve net working capital settlement
                                                                              
          acquisitions, net of cash acquired
                                                                              
          proceeds from public offering, net of 17.7 million in offering costs
                         269,825,000                                                   
          conversion of series c preferred stock to common stock
                         765,000                                                   
          cost of series c preferred stock conversion included in additional paid-in-capital and accounts payable and accrued liabilities
                         1,800,000                                                   
          cryopdp goodwill adjustment included in deferred tax liability
                         53,000 -517,000 1,394,000                                                   
          cryopdp goodwill adjustment included in fixed assets
                         -1,000 71,000                                                   
          fair value adjustment of ctsa contingent consideration included in goodwill and contingent consideration
                                                                              
          note valuation adjustment included in notes payable and goodwill
                                                                              
          net unrealized loss on available-for-sale securities
                     -6,538,000 -33,439,000 14,065,000                                                       
          acquisition of cell&co
                                                                              
          acquisition of ctsa and f-airgate
                         -21,000                                                     
          repayment of capital lease obligation
                                                                              
          mve estimated working capital adjustment included in goodwill and accounts payable
                                                                              
          deferred tax liability
                       60,000  768,000 25,000 80,000  -9,002 27,008 9,002                                               
          mve goodwill adjustment included in fixed assets
                                                                              
          note valuation adjustment included in note payable and goodwill
                         9,000 -991,000 1,266,000                                                   
          interest expense on convertible note settled by issuance of common stock
                                                                              
          accelerated stock-based compensation expense
                                -1,227,890                                              
          proceeds from the issuance of convertible senior notes
                                                                              
          fair value adjustment of ctsa contingent consideration included in goodwill and contingent consideration accrual
                                                                              
          net unrealized gain on available-for-sale securities
                         -366,000 -1,946,000 768,000  -85,103 -135,178 470,924                                               
          purchase of equipment through capital lease obligations
                               202,619                                               
          financing costs included in accounts payable and accrued liabilities
                                                                              
          convertible debt costs included in accounts payable and accrued liabilities
                                                                              
          cash paid for acquisition
                                112,944                                             
          proceeds from june 2019 public offering, net of offering costs
                                 3,272                                             
          realized gain on treasury notes and bills
                                -19,189 -32,573                                             
          warrant inducement and repricing expense
                                    899,410                                       
          property and equipment disposal costs
                                                                              
          accrued interest
                                        -1,843 -2,006 9,018 6,027 -18,988 -1,186 21,524 10,466 7,854 18,110 22,674 8,961 46,340 30,063 19,933 10,364 10,744 -1,483 24,031 11,814 11,799 12,581 13,444 14,127 14,574 15,011 11,679 45,826 121,919 156,406 151,863 45,235 16,354 118,164 
          maturities of short-term investments
                                2,000,000 1,995,000                                             
          proceeds from issuance of convertible debt
                                                      1,352,000 591,000 1,657,150 958,151                     
          proceeds from issuance of common stock, net of costs
                                                                              
          proceeds from tender offer, net of offering costs
                                                                              
          proceeds from the atm, net of offering costs
                                                                              
          leasehold improvements paid by tenant allowance
                                                                              
          proceeds from february 2018 tender offer, net of offering costs
                                    4,641,807                                       
          proceeds from atm, net of offering costs
                                                                              
          change in net unrealized loss on available-for-sale securities
                                                                              
          change in net unrealized gain on available-for-sale securities
                                  28,740 30,872                                           
          maturity of short-term investment
                                   500,000                                           
          amortization of debt discount and deferred financing costs
                                                  220,152 38,140 1,110,013 138,267 25,267 464,498 50,883                     
          unrealized loss on short-term equity securities
                                                                              
          stock-based compensation expense to employees, directors and consultants
                                              826,926                                
          repayment of related-party notes payable
                                        -563,842 -92,379 -128,140 -98,831                                 
          deferred offering costs in connection with future warrant repricing included in accounts payable and prepaid expenses and other current assets
                                                                              
          amortization of debt discounts and deferred financing costs
                                         6,130 6,266 6,197  65,435 65,435 286,133                             
          prepaid expenses and other assets
                                     -379,524                                1,915 -43,652 -36,210 25,993 3,650 -121,864 40,727 59,465 29,001 
          proceeds from the public offering, net of offering costs
                                                                              
          supplemental disclosure of non-cash investing activities:
                                                                              
          unrealized loss on available-for-sale securities
                                                                              
          reduction of accounts payable for returned fixed assets
                                                                              
          offering costs included in additional paid-in capital and accounts payable and other accrued expenses
                                           165,990                                   
          patent costs
                                                                              
          proceeds from the april 2016 tender offer, net of offering costs
                                                                              
          proceeds from the rights offering, net of offering costs
                                            -186,652 1,185,368                                 
          proceeds from the october 2016 tender offer, net of offering costs
                                                                              
          cumulative undeclared preferred dividends recorded upon conversion of class a convertible preferred stock and class b convertible preferred stock into common stock
                                                                              
          estimated relative fair value of warrants issued in connection with related-party notes payable
                                                                              
          leasehold improvements paid by tenant allowance included in accounts payable and accrued expenses
                                                                              
          reclassification of shipper inventory to property and equipment
                                                                              
          warrant repricing expense
                                            1,929,818                                 
          trademark costs
                                         -26,805 -14,529 -10,199                                   
          proceeds from the common stock offering, net of offering costs
                                         -165,990 11,571,914                                   
          proceeds from april 2016 tender offer, net of offering costs
                                                                              
          proceeds from exercise of stock options and warrants, net of costs
                                                                              
          cumulative undeclared preferred dividends recorded upon conversion of class a convertible preferred stock and class b convertible preferred stock into common
                                                                              
          reclassification of shipper inventory to fixed assets
                                                                             
          leasehold improvements paid by tenant allowance included in accounts payable and other accrued expenses
                                                                              
          issuance of common stock for accrued board of director compensation
                                                                            
          estimated fair value of the beneficial conversion feature on related-party notes payable
                                                                              
          other assets
                                            -342,072 -16,022   -66,144 -25,192 55,196 -37,101 5,467 -13,388         18,214                
          acquisition of intangible
                                                                              
          proceeds from the tender offer, net of offering costs
                                            -46,200 2,290,447                                 
          proceeds from issuance of common stock and warrants in public offering, net of offering costs
                                                                             
          proceeds from the issuance of class a and class b convertible preferred stock, net of offering costs
                                                                              
          offering costs in connection with the rights offering included in accounts payable and other accrued expenses
                                                                              
          purchase of fixed assets included in accounts payable and other accrued expenses
                                                                              
          accretion of convertible preferred stock beneficial conversion feature and relative fair value of warrants issued in connection with the convertible preferred stock units to accumulated deficit
                                              4,474,348 1,902,569 492,910 1,727,027 741,786                         
          adjustments to reconcile net loss to net cash used in operating activities:
                                                                              
          payment for deferred offering costs
                                                 -89,545                             
          offering costs in connection with tender offer included in accounts payable and other accrued expenses
                                             46,200                                 
          offering costs in connection with rights offering included in accounts payable and other accrued expenses
                                             184,690                                 
          offering costs for future financing included in prepaid expenses and other current assets and accounts payable and other accrued expenses
                                             24,204                                 
          deferred offering costs in connection with secondary public offering included in accounts payable and other accrued expenses
                                                                              
          estimated relative fair value of beneficial conversion feature on related-party notes payable
                                                                              
          loss on write-off of patents
                                                                             
          proceeds from the issuance of notes payable
                                                                              
          repayment of convertible debt
                                                                              
          repayment of offering and deferred financing costs
                                                         -67,475                     
          estimated relative fair value of warrants issued in connection with notes payable
                                                  146,257                            
          conversion of convertible debentures payable and accrued interest into convertible preferred stock units
                                                  1,766,997                         
          estimated fair value of the beneficial conversion feature on related party notes payable
                                                                              
          deposits and other current assets
                                                                              
          proceeds from the issuance of preferred stock, net of offering costs
                                               3,896,678  1,140,290 882,222 780,342                         
          repayment of convertible debentures
                                                   -50,000                         
          repayment of related party notes payable
                                               -40,000 -60,000 -112,000  -24,000 -24,000 -24,000                         
          offering costs in connection with convertible preferred stock included in accounts payable
                                                   9,658                         
          fair value of common stock issued to consultant for future services included in other current assets
                                                                              
          loss on disposal of cryogenic shippers
                                                  10,650 3,909 179 1,685 10,182 3,075   44,651       3,007 897 2,613 13,674        
          provision for (recovery of) bad debt
                                                 3,340                             
          deferred offering costs in connection with secondary public offering included in accounts payable
                                                 51,153                             
          change in fair value of derivative instruments
                                                      -3 -1,196 -892 -18,757 11,226 6,112 -14,489 -19,335 -10,010 -60,185 -14,685 -34,283 227,270 -33,987 -126,345 -116,528         
          debt conversion expense
                                                      552,750                       
          deferred financing costs in connection with convertible debt payable included in accounts payable
                                                        -42,491 70,234                     
          estimated relative fair value of warrants issued in connection with convertible bridge notes payable
                                                                              
          estimated relative fair value of warrants issued in connection with related-party convertible notes payable
                                                                              
          conversion of bridge notes payable and accrued interest into common stock units
                                                                              
          proceeds from issuance of notes payable
                                                                              
          proceeds from issuance of convertible debentures
                                                                              
          repayment of offering and deferred costs
                                                                              
          estimated relative fair value of warrants issued in connection with convertible debentures payable
                                                                              
          conversion of bridge notes payable and accrued interest into shares of common stock and warrants
                                                       150,027                       
          net decrease in cash and cash equivalents
                                                    -67,162 -199,076                         
          deferred financing costs in connection with convertible debentures payable included in accounts payable
                                                                              
          recovery of bad debt
                                                     -5,349                         
          loss on write-off of intangible assets
                                                                              
          reserve for bad debt
                                                                              
          purchases of intangible assets
                                                              -207 -45,666 -54,210 -25,337 -28,571 -21,537          
          offering costs in connection with equity financing included in accounts payable
                                                          -5,822                   
          release of restricted cash for repayment of convertible debentures
                                                                              
          cash flows from operating activities
                                                                              
          fair value of stock options and warrants issued to employees, directors and consultants
                                                       178,746 174,017 157,203                     
          other current assets
                                                       -13,271 1,140 -10,767  -18,400 -1,045 28,385   60,893 64,448             
          accounts payable and accrued expenses
                                                       350,935 -167,242 -54,278 142,143 223,125 47,406 30,894 -400,716 159,725 142,752 35,998 50,524            
          cash flows from investing activities
                                                                              
          cash flows from financing activities
                                                                              
          repayments of convertible debt
                                                                              
          payments of offering and deferred financing costs
                                                       -115,880                       
          repayments of related party notes payable
                                                       -24,000 -24,000 -24,000  -32,000 -24,000 -16,000  -24,000 -24,000 -30,000      -20,000 -30,000 -30,000 -30,000 -30,000 -30,000 -30,000 
          cash and cash equivalents, beginning of period
                                                       563,104  4,617,535  9,278,443      249,758  2,231,031 
          cash and cash equivalents, end of period
                                                       -312,499 304,939 227,530  -1,084,527 -1,301,933 2,971,567  -2,157,365 -2,103,150 7,056,604      -473,450 563,836 556,922  -442,880 -970,652 2,189,698 
          supplemental disclosure of cash flow information
                                                                              
          cash paid during the period for:
                                                                              
          interest
                                                          3,099 12,577 24,547 38,413 50,345 22,727 1,741 12,967 2,133         
          income taxes
                                                            1,600 1,600         
          release of restricted cash for repayment of convertible debentures payable
                                                          251,368                 
          estimated relative fair value of warrants issued in connection with convertible debt payable
                                                        92,171 106,999                     
          operating activities
                                                                              
          fair value of warrants issued to convertible debenture holders
                                                                              
          fair value of stock options and warrants issued to consultants, employees and directors
                                                            168,190 80,836 31,110 157,441 198,949 171,591    152,067    272,312     
          interest accrued on restricted cash
                                                              -126 -148 -145 -166 -228 -226     -477    
          investing activities
                                                                              
          financing activities
                                                                              
          proceeds from issuance of common stock, net of cash paid for issuance costs
                                                                  8,090,745            
          restricted cash – convertible debenture holder escrow account funds
                                                                              
          proceeds from release of restricted cash
                                                                            
          payment on line of credit
                                                                            
          proceeds from exercise of options and warrants
                                                                      437,500   -1 3,308 
          cash and cash equivalents, beginning of year
                                                                    3,629,886         
          cash and cash equivalents, end of year
                                                                    1,648,543 2,097,202         
          cash paid during the year for:
                                                                              
          cashless exercise of warrants and stock options
                                                                              
          repayments of convertible debentures payable
                                                           -82,800  -600,000 -600,000 -576,628             
          proceeds from exercise of warrants
                                                               115,500 324,133 132,000             
          supplemental disclosure of non-cash activities:
                                                                              
          cashless exercise of warrants
                                                                              
          payment of financing costs
                                                             -78,480                
          repayment of convertible debentures payable
                                                                              
          repayment of deferred financing costs
                                                                              
          proceeds from private placement of common stock, net of cash paid for issuance costs
                                                                              
          restricted cash-investor funds
                                                                              
          deposits from investors
                                                                              
          amortization of deferred financing costs
                                                                      77,760 56,177 17,675 7,904 3,589 10,766 10,767 17,162 
          fair value of stock issued to consultants
                                                                              
          share-based compensation related to stock options and warrants issued to consultants, employees and directors
                                                                  86,305 51,871           
          loss on sale of assets
                                                                      8,387 797     
          accrued warranty costs
                                                                        -5,625 -5,625 
          decrease in restricted cash
                                                                      -2,085        
          proceeds from borrowings under convertible notes
                                                                            
          repayments of note payable to officer
                                                                      -113,950   -12,000 -6,000 -18,000 -18,000 
          payment of fees associated with the exercise of warrants
                                                                              
          payment of related party notes payable
                                                                   -30,000 -30,000 -30,000         
          payment of fees associated with exercise of warrants
                                                                       -25,458       
          stock issued to consultants
                                                                      47,287 12,000 106,807 80,332 63,100 77,170 28,500 
          accounts payable
                                                                    120,908 -205,513 179,451 -54,265 72,375 102,893 -113,531 83,131 12,974 1,561 
          net cash provided by financing activities
                                                                              
          inventory
                                                                              
          accrued compensation and related expense
                                                                     9,293         
          purchases of intangibles
                                                                     -44,381        
          accrued expenses
                                                                      -105,482 -97,436 112,278 93 -7,518 -338 -9,643 9,398 
          repayment of line of credit
                                                                              
          fair value of warrants and options issued to employees and directors
                                                                              
          fair value of warrants issued to consultants
                                                                              
          change in fair value of derivative instrument
                                                                       -4,508,352 4,535,848 -3,134,298     
          interest earned on restricted cash
                                                                       -465 -597   -2,276 -2,250 
          accrued salaries and related
                                                                       -17,897 23,622 14,928 8,764 67,538 -3,871 -4,354 
          purchases of fixed assets
                                                                       -8,201 -1 -9,766 -300 -5,235 -23,544 -29,499 
          net cash (used in) provided by investing activities
                                                                              
          repayment of convertible notes
                                                                           -117,720 
          repayment of borrowings on line of credit
                                                                           -3,000 -10,000 -12,500 
          fair value of warrants issued to employees and directors
                                                                           -168,244   
          payment of trademark costs
                                                                         -18,020   -633 
          net proceeds from borrowings under convertible notes
                                                                         926,500  1,062,500 
          fair value of warrants issued to consultants, employees and directors
                                                                              
          cash flows provided by (used in) investing activities:
                                                                              
          net cash from (used in) investing activities
                                                                              
          net proceeds from borrowings under line of credit
                                                                              
          proceeds from issuance of common stock
                                                                              
          decrease (increase) in restricted cash
                                                                              
          fair value of stock options and warrants issued to employees and directors
                                                                             53,887 
          investment in certificate of deposit
                                                                              
          proceeds from borrowings under notes payable
                                                                              
          cash flows used in investing activities: