7Baggers
Quarterly
Annual
    Unit: USD2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-03-31 
      
                       
      cash flows from operating activities:
                       
      net income
    -441,885,000 -116,897,000 -199,581,000 -173,228,000 -210,259,000 -265,328,000 -218,116,000 -196,628,000 -180,934,000 -172,937,000 -149,264,000 -106,167,000 -211,070,000 -62,304,000 -54,750,000 -61,441,000 -39,269,000 -85,462,000 -18,753,000 
      adjustments to reconcile net income to net cash from operating activities:
                       
      non-cash share-based compensation expense
    40,266,000 81,828,000 24,849,000 27,966,000 25,586,000 48,726,000 14,208,000 14,565,000 11,762,000 16,879,000 20,117,000 9,971,000 17,554,000 7,330,000      
      interest expense on mandatorily redeemable preferred shares
     7,917,000  8,144,000 8,042,000 7,943,000              
      interest expense on liability related to sale of future royalties
    18,045,000 17,314,000  15,488,000 14,499,000 13,508,000              
      deferred interest paid-in-kind on long-term debt
    6,587,000 6,450,000                  
      acquisition of ipr&d asset
                       
      issuance of common shares as payment for license agreement
    1,779,000                  
      change in fair value of derivatives
    111,197,000 -3,604,000 -760,000 1,893,000   12,250,000             
      gain from equity method investment
                       
      depreciation and amortization
    5,381,000 4,402,000 7,947,000 5,707,000 6,224,000 5,054,000 4,822,000             
      change in obligation to perform r&d services
    -5,384,000 -6,942,000 -11,349,000 -9,213,000                
      other non-cash items
    1,019,000 -646,000 -1,891,000 -1,332,000 1,632,000 461,000  -1,621,000 1,225,000 476,000 209,000 166,000 138,000 133,000 178,000 38,000    
      changes in operating assets and liabilities:
                       
      trade receivable
    -24,107,000 -20,073,000                  
      inventory
    -5,691,000 -23,397,000                  
      prepaid expenses, other current assets, and other assets
    -10,319,000 -24,954,000                  
      accounts payable
    7,948,000 4,518,000 1,996,000 -4,866,000 -8,818,000 13,903,000 4,909,000 26,964,000 -13,541,000 14,475,000 2,509,000 -1,307,000 4,659,000 -2,542,000 5,453,000 631,000 -4,918,000 4,224,000 2,656,000 
      accrued expenses, other current liabilities, and other liabilities
    77,077,000 48,661,000                  
      net cash from operating activities
    -134,036,000 -23,644,000 -193,392,000 -204,992,000 -227,042,000 -205,674,000 -212,238,000 -164,106,000 -175,813,000 -150,722,000 -100,447,000 -70,128,000 -159,887,000 -46,869,000 -33,416,000 -48,736,000    
      capex
    -1,881,000 -512,000 -52,000 -9,000 -470,000 -1,187,000 -869,000 -120,000 -365,000 -1,016,000 -897,000 -189,000 -410,000 -1,038,000 -1,531,000 -1,133,000    
      free cash flows
    -135,917,000 -24,156,000 -193,444,000 -205,001,000 -227,512,000 -206,861,000 -213,107,000 -164,226,000 -176,178,000 -151,738,000 -101,344,000 -70,317,000 -160,297,000 -47,907,000 -34,947,000 -49,869,000    
      cash flows from investing activities:
                       
      purchases of marketable securities
    -246,816,000                  
      sales of marketable securities
                      
      maturities of marketable securities
    59,835,000 3,058,000 8,000,000                 
      purchases of property and equipment
    -1,881,000 -512,000 -52,000 -9,000 -470,000 -1,187,000 -869,000 -120,000 -365,000 -1,016,000 -897,000 -189,000 -410,000 -1,038,000 -1,531,000 -1,133,000    
      payment for intangible asset
                       
      payment for ipr&d asset acquisition
                       
      net cash from investing activities
    56,969,000 -244,270,000 -174,314,000 40,230,000 40,867,000 119,769,000 4,954,000 -250,353,000 -1,115,000 -23,366,000 -2,147,000 -189,000 -410,000 -1,038,000 -6,531,000 -1,133,000    
      cash flows from financing activities:
                       
      proceeds from issuance of long-term debt
                     
      proceeds from issuance of common shares
    252,000,000 308,743,000 283,333,000 21,221,000   135,125,000 55,000,000  
      proceeds from obligation to perform r&d services
      100,000,000             
      proceeds from the issuance of series b preferred shares
    14,579,000 14,579,000  17,585,000 17,585,000 17,585,000              
      proceeds from exercise of share options
    7,180,000 2,803,000    1,382,000              
      payments for term loan, finance leases, and other
    -4,833,000 -1,391,000                  
      net cash from financing activities
    141,926,000 267,991,000 37,064,000 361,598,000 25,172,000 421,015,000 19,367,000 472,306,000 11,551,000 285,600,000 2,747,000 22,152,000 408,629,000 1,065,000 136,011,000 602,000 147,846,000 56,003,000 37,951,000 
      effect of exchange rate changes on cash, cash equivalents and restricted cash
    -2,676,000 -46,000  -158,000 -203,000 14,000              
      net increase in cash, cash equivalents and restricted cash
    62,183,000 31,000 -330,484,000 196,678,000 -161,206,000 335,124,000 -187,802,000             
      cash, cash equivalents and restricted cash at beginning of period
    174,343,000 134,231,000             
      cash, cash equivalents and restricted cash at end of period
    62,183,000 174,374,000 -330,484,000 196,678,000 -161,206,000 469,355,000 -187,802,000             
      deferred interest on mandatorily redeemable preferred shares
                       
      deferred interest on liability related to sale of future royalties
                       
      issuance of common shares as payment for license and consulting agreements
      3,686,000 4,243,000              
      trade receivables
      -55,317,000 -84,315,000 -11,868,000 -36,658,000 -40,589,000 -34,726,000 -40,459,000 -4,337,000          
      inventories
      11,199,000 -16,255,000 -1,480,000 -17,566,000 -19,841,000 -11,193,000 -3,322,000 -3,609,000          
      prepaid expenses and other current assets
         -24,808,000 -35,281,000 -11,708,000 -8,647,000 -25,733,000 -4,958,000 2,017,000 1,353,000 -1,876,000 6,705,000 -4,645,000    
      other assets
        -79,021,000 -811,000 -1,000 -62,000 -3,000 20,000 108,000 -327,000 12,000 -25,000 53,000 -21,000    
      accrued expenses and other current liabilities
        3,202,000 60,666,000 26,669,000 23,867,000 38,683,000 2,860,000          
      other long-term liabilities
        -15,387,000 -12,751,000 7,738,000 25,000 37,000 25,000 -1,000 -1,999,000 -52,000 672,000   6,000 
      purchase of marketable securities
                       
      payments for leasehold improvements
          -1,600,000          
      payments for intangible assets
          -20,000,000 -750,000 -20,750,000          
      proceeds from sale of future royalties
                    
      proceeds from sale of contingently redeemable non-controlling interests
                      
      proceeds from issuance of mandatorily redeemable preferred shares
                     
      proceeds from exercise of warrants
                     
      proceeds from exercise of share options and employee share purchase plan
      21,977,000 6,263,000                
      payments for term loan, finance leases and other
                       
      effect of exchange rates on cash, cash equivalents and restricted cash
                       
      supplemental disclosure of cash flow information:
                       
      cash paid for interest
          4,419,000            25,000 
      cash paid for income taxes
          1,460,000    -12,000 407,000 20,000 408,000 60,000 250,000 -57,000 80,000  
      interest expense paid-in-kind on long-term debt
       3,331,000 2,854,000 2,795,000              
      (gain) income from equity method investment
       -5,261,000              
      accrued expenses and other liabilities
                       
      proceeds from the sale of contingently redeemable non-controlling interests
                       
      prepaid expenses
                       
      other current assets
                       
      sales and maturities of marketable securities
        41,337,000 120,956,000              
      payment of term loan commitment fee
        -3,750,000              
      payment of principal for finance leases
        -1,264,000 -1,250,000              
      payment of term loan
        -1,195,000              
      other
                       
      change in fair value of derivative liability
         210,000   -650,000 5,781,000 895,000 1,717,000        
      payments of issuance costs
         -500,000  -1,800,000 -160,000 -340,000 -633,000       
      non-cash interest expense on mandatorily redeemable preferred shares
          7,759,000 7,310,000 6,993,000 5,561,000 4,378,000 4,378,000        
      non-cash interest expense on liability related to sale of future royalties
          13,288,000 11,955,000 11,570,000 8,425,000 7,308,000 7,308,000 5,151,000 6,813,000  5,633,000    
      non-cash interest expense on long-term debt
                       
      non-cash issuance of common shares as payment for license agreement
                       
      change in fair value of warrant liability
                  1,182,000 454,000 
      income from equity method investment
          690,000 607,000 1,485,000 1,380,000 1,768,000 1,993,000 1,415,000 900,000 742,000 697,000 641,000 728,000 218,000 
      purchase of equity method investment
                  -5,000,000    
      proceeds from issuance of common stock related to sale of future royalties
                     
      payments of issuance costs and term loan commitment fee
                       
      payments of principal for finance leases
                       
      non-cash expense related to license agreement
                       
      proceeds from exercise of stock options
           3,460,000 11,748,000 2,607,000 2,747,000 1,564,000 148,000 1,065,000 886,000 602,000 833,000 1,003,000  
      repayment of principal for finance leases
           -954,000            
      net increase in cash and restricted cash
            -165,377,000 111,512,000 -99,847,000         
      cash and restricted cash at beginning of period
            317,727,000         
      cash and restricted cash at end of period
            -165,377,000 429,239,000 -99,847,000         
      cash
            -167,178,000 428,239,000          
      restricted cash
            801,000 1,000,000          
      total cash and restricted cash in the statement of cash flows
            -165,377,000 429,239,000          
      supplemental disclosure of non-cash investing and financing activities:
                       
      deferred offering costs included in accounts payable
             160,000          
      intangible asset costs included in accounts payable
             20,750,000          
      non-cash interest expense
                      280,000 
      change in fair value of contingent equity liability
                      3,375,000 
      deferred tax assets
                       
      accrued expenses
              16,458,000 4,477,000 15,684,000 6,701,000 -1,824,000 1,878,000   2,991,000 
      payments of related party notes payable
                       
      repayment of notes payable
                       
      deferred offering costs included in accounts payable and accrued expenses
                     2,987,000 1,515,000 
      beneficial conversion feature on series a preferred shares
                      12,006,000 
      accretion of beneficial conversion feature on series a preferred shares
                      4,000,000 
      issuance of series a preferred shares as payment of offering costs
                      1,242,000 
      issuance of common shares as payment of equity investment
                       
      purchases of property and equipment under financing lease
                       
      offering costs included in accounts payable and accrued expenses
                      
      level 1
                       
      liabilities:
                       
      derivative liability
                       
      net increase in cash
                248,332,000 -46,842,000 96,064,000 -49,267,000   28,721,000 
      cash at beginning of period
                264,249,000 131,468,000 23,565,000 
      cash at end of period
                248,332,000 217,407,000 96,064,000 -49,267,000 113,246,000 104,206,000 52,286,000 
      •
                       
      balance at december 31, 2017
                 4,021,000      
      change in fair value
                 1,182,000      
      reclassification to equity
                 -5,203,000      
      balance at march 31, 2018
                       
      non-cash interest expense on non-recourse debt related to sale of future royalties
                       
      fair value of contingent equity liability under license agreements
                       
      fair value of warrants issued as consideration for license agreement
                       
      proceeds from issuance of series a preferred shares
                      40,000,000 
      proceeds from borrowings
                       
      payments of offering costs
                       
      payments of debt issuance costs
                       
      advanced payment for the second closing of series a preferred stock
                       
      deferred offering costs included in accrued expenses
                       
      series a convertible preferred share offering costs included in accrued expenses
                       
      issuance of warrants to guarantor and co-guarantor of notes payable
                       
      issuance of series a preferred shares in settlement of contingent equity liability
                       
      issuance of notes payable to related parties in connection with acquisition of bpi
                       
      building
                       
      office equipment
                       
      computer software
                       
      computer equipment
                       
      share-based compensation expense
                   3,742,000 5,608,000 3,088,000 1,886,000 
      warrant liability
                       
      depreciation expense
                     17,000 4,000 
      deferred series a offering costs included in accrued expenses
                      65,000 
      decrease in restricted cash
                      67,000 
      issuance of common shares as payment for equity investment
                      352,000 
      contingent equity liability
                       
    The information provided in this report is taken from www.sec.gov and many other data providers. While we have conducted our best efforts to ensure that the parsed data is accurate, we cannot guarantee its accuracy. Please use caution and understand that any consequences of its use are your own responsibility.