7Baggers

BeiGene, Ltd
(NASDAQ:BGNE) 

BGNE stock logo

BeiGene, Ltd., a commercial-stage biotechnology company, engages in discovering, developing, manufacturing, and commercializing medicines for cancer therapeutics in the People's Republic of China and the United States. Its commercial products include BRUKINSA to treat relapsed/refractory (R/R) mantl...

Founded: 2010
Full Time Employees: 9,400 (Dec 2022)
Sector: Healthcare
Industry: Biotechnology

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Quarterly
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    Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 
                                             
      revenues
                                             
      product revenue
    1,487,329,000 1,476,442,000 1,395,013,000 1,302,076,000 1,108,530,000 1,118,035,000 993,447,000 921,146,000 746,918,000 630,526,000 595,290,000 553,745,000 410,291,000 339,022,000 349,506,000 304,511,000 261,573,000 196,785,000 192,461,000 138,624,000 106,117,000 100,100,000 91,080,000 65,635,000 52,059,000 56,892,000 50,141,000 58,142,000 57,421,000 37,762,000 38,447,000 31,426,000 23,250,000 15,606,000 8,822,000       
      other revenue
    26,109,000 21,728,000 17,271,000                                       
      total revenues
    1,513,438,000 1,498,170,000 1,412,284,000 1,315,300,000 1,117,279,000 1,127,824,000 1,001,599,000 929,166,000 751,652,000 634,409,000 781,308,000 595,261,000 447,801,000 380,095,000 387,628,000 341,572,000 306,626,000 213,979,000 206,440,000 149,992,000 605,872,000 100,100,000 91,080,000 65,635,000 52,059,000 56,892,000 50,141,000 243,346,000 77,833,000 58,670,000 54,202,000 52,804,000 32,544,000 18,174,000 220,213,000       
      yoy
    35.46% 32.84% 41.00% 41.56% 48.64% 77.78% 28.20% 56.09% 67.85% 66.91% 101.56% 74.27% 46.04% 77.63% 87.77% 127.73% -49.39% 113.77% 126.66% 128.52% 1063.82% 75.95% 81.65% -73.03% -33.11% -3.03% -7.49% 360.85% 139.16% 222.82% -75.39%           
      qoq
    1.02% 6.08% 7.37% 17.72% -0.93% 12.60% 7.80% 23.62% 18.48% -18.80% 31.25% 32.93% 17.81% -1.94% 13.48% 11.40% 43.30% 3.65% 37.63% -75.24% 505.27% 9.90% 38.77% 26.08% -8.50% 13.46% -79.40% 212.65% 32.66% 8.24% 2.65% 62.25% 79.07% -91.75%        
      cost of sales - product
    167,215,000 142,422,000 196,510,000 164,606,000 165,002,000 160,560,000 170,462,000 138,132,000 124,935,000 105,832,000 96,309,000 95,990,000 81,789,000 73,522,000 76,543,000 71,173,000 65,237,000 48,545,000 47,413,000 36,263,000 32,685,000 21,078,000 21,123,000 14,307,000 14,149,000 -17,984,000 -20,106,000 -17,839,000 -15,261,000 -9,193,000 -8,706,000 -6,256,000 -4,550,000 -3,030,000 -1,944,000       
      gross profit
    1,346,223,000 1,355,748,000 1,215,774,000 1,150,694,000 952,277,000 967,264,000 831,137,000 791,034,000 626,717,000 528,577,000 684,999,000 499,271,000 366,012,000 306,573,000 311,085,000 270,399,000 241,389,000 165,434,000 159,027,000 113,729,000 573,187,000 79,022,000 69,957,000 51,328,000 37,910,000 38,908,000 30,035,000 225,507,000 62,572,000 49,477,000 45,496,000 46,548,000 27,994,000 15,144,000 218,269,000       
      yoy
    41.37% 40.16% 46.28% 45.47% 51.95% 82.99% 21.33% 58.44% 71.23% 72.41% 120.20% 84.64% 51.63% 85.31% 95.62% 137.76% -57.89% 109.35% 127.32% 121.57% 1411.97% 103.10% 132.92% -77.24% -39.41% -21.36% -33.98% 384.46% 123.52% 226.71% -79.16%           
      qoq
    -0.70% 11.51% 5.66% 20.84% -1.55% 16.38% 5.07% 26.22% 18.57% -22.84% 37.20% 36.41% 19.39% -1.45% 15.05% 12.02% 45.91% 4.03% 39.83% -80.16% 625.35% 12.96% 36.29% 35.39% -2.57% 29.54% -86.68% 260.40% 26.47% 8.75% -2.26% 66.28% 84.85% -93.06%        
      gross margin %
    88.95% 90.49% 86.09% 87.49% 85.23% 85.76% 82.98% 85.13% 83.38% 83.32% 87.67% 83.87% 81.74% 80.66% 80.25% 79.16% 78.72% 77.31% 77.03% 75.82% 94.61% 78.94% 76.81% 78.20% 72.82% 68.39% 59.90% 92.67% 80.39% 84.33% 83.94% 88.15% 86.02% 83.33% 99.12% NaN% NaN% NaN% NaN% NaN%  
      operating expenses
                                             
      research and development
    541,224,000 615,423,000 523,662,000 524,896,000 481,887,000 542,012,000 496,179,000 454,466,000 460,638,000 493,987,000 453,259,000 422,764,000 408,584,000 446,023,000 426,363,000 378,207,000 389,915,000 430,485,000 351,937,000 356,091,000 320,726,000 355,537,000 349,070,000 285,968,000 304,302,000 -283,259,000 -236,968,000 -228,760,000 -178,351,000 -257,464,000 -147,590,000 -164,251,000 -109,700,000 -91,340,000 -87,660,000 -47,245,000      
      selling, general and administrative
    555,097,000 555,290,000 528,998,000 537,913,000 459,288,000 504,677,000 455,223,000 443,729,000 427,427,000 416,547,000 364,421,000 395,034,000 328,499,000 328,984,000 322,892,000 331,403,000 294,573,000 306,501,000 269,227,000 232,289,000 182,106,000 208,209,000 160,837,000 124,049,000 107,081,000 -143,354,000 -105,002,000 -82,248,000 -57,645,000 -72,490,000 -48,820,000 -45,160,000 -28,915,000 -27,415,000 -15,641,000       
      total operating expenses
    1,096,321,000 1,170,713,000 1,052,660,000 1,062,809,000 941,175,000 1,046,689,000 951,402,000 898,195,000 888,065,000                           -58,022,000      
      income from operations
    249,902,000 185,035,000 163,114,000 87,885,000 11,102,000 -79,425,000 -120,265,000 -107,161,000 -261,348,000 -383,795,000 -133,968,000 -318,715,000 -371,258,000 -468,622,000 -438,357,000 -439,399,000 -443,287,000 -571,739,000 -462,325,000 -474,838,000 70,167,000 -484,912,000 -440,137,000 -358,877,000 -373,756,000 -388,037,000 -312,266,000 -85,833,000 -173,755,000 -280,808,000 -151,102,000 -163,050,000 -110,809,000 -103,798,000 114,905,000 -58,022,000      
      yoy
    2150.96% -332.97% -235.63% -182.01% -104.25% -79.31% -10.23% -66.38% -29.60% -18.10% -69.44% -27.47% -16.25% -18.04% -5.18% -7.46% -731.76% 17.91% 5.04% 32.31% -118.77% 24.97% 40.95% 318.11% 115.11% 38.19% 106.66% -47.36% 56.81% 170.53% -231.50% 181.01%          
      qoq
    35.06% 13.44% 85.60% 691.61% -113.98% -33.96% 12.23% -59.00% -31.90% 186.48% -57.97% -14.15% -20.78% 6.90% -0.24% -0.88% -22.47% 23.67% -2.64% -776.73% -114.47% 10.17% 22.64% -3.98% -3.68% 24.26% 263.81% -50.60% -38.12% 85.84% -7.33% 47.15% 6.75% -190.33% -298.04%       
      operating margin %
    16.51% 12.35% 11.55% 6.68% 0.99% -7.04% -12.01% -11.53% -34.77% -60.50% -17.15% -53.54% -82.91% -123.29% -113.09% -128.64% -144.57% -267.19% -223.95% -316.58% 11.58% -484.43% -483.24% -546.78% -717.95% -682.06% -622.78% -35.27% -223.24% -478.62% -278.78% -308.78% -340.49% -571.13% 52.18% -Infinity% NaN% NaN% NaN% NaN%  
      interest income
    27,664,000 58,131,000 3,029,000 3,497,000 5,848,000 7,808,000 10,643,000 13,225,000 16,160,000 16,274,000 26,649,000 15,070,000 16,016,000 18,219,000 12,759,000 11,431,000 10,071,000 -4,482,000 -2,230,000 -4,866,000 -4,179,000 -5,186,000 -614,000 1,108,000 6,690,000 -438,000 2,206,000 2,886,000 4,477,000 5,950,000 4,553,000 1,892,000 1,552,000 -527,000 -1,785,000 -1,982,000 186,000 209,000 262,000 494,000  
      interest expense
    -32,887,000                                         
      other income
    14,536,000 -35,691,000 -18,979,000 8,167,000 3,950,000 -13,734,000 11,318,000  1,762,000 16,749,000 336,657,000  18,303,000 19,438,000 -125,640,000  11,967,000 -10,583,000 31,477,000 -867,000 -4,123,000 8,122,000 5,711,000 19,976,000 3,681,000 8,141,000 -1,817,000 -878,000 1,728,000 -396,000 1,585,000 75,000 729,000 9,926,000 1,103,000 -477,000 905,000 198,000 748,000 315,000  
      income before income taxes
    259,215,000 149,241,000 147,164,000 99,549,000 20,900,000 -85,351,000 -98,304,000 -105,920,000 -243,426,000 -350,772,000 229,338,000 -367,463,000 -336,939,000 -430,965,000 -551,238,000 -557,585,000 -421,249,000 -586,804,000 -433,078,000 -480,571,000 61,865,000 -481,976,000 -435,040,000 -337,793,000 -363,385,000 -140,813,000 -311,877,000 -83,825,000 -167,550,000             
      income tax expense
    31,858,000 82,739,000 22,323,000 5,229,000 19,630,000 66,530,000 23,046,000 14,485,000 7,724,000 16,781,000 13,925,000 13,674,000 11,492,000 14,370,000 6,318,000 13,864,000 13,025,000   -230,000 -4,630,000   -1,475,000 1,554,000           -201,000      
      net income
    227,357,000 66,502,000 124,841,000 94,320,000 1,270,000 -151,881,000 -121,350,000 -120,405,000 -251,150,000 -367,553,000 215,413,000 -381,137,000 -348,431,000 -445,335,000 -557,556,000 -571,449,000 -434,274,000 -585,653,000 -413,855,000 -480,341,000 66,495,000 -472,649,000 -426,617,000 -336,318,000 -364,939,000 -387,895,000 -308,660,000 -85,954,000 -168,069,000 -266,710,000 -144,492,000 -157,715,000 -105,116,000 -99,280,000 117,284,000 -60,680,000      
      yoy
    17802.13% -143.79% -202.88% -178.34% -100.51% -58.68% -156.33% -68.41% -27.92% -17.47% -138.64% -33.30% -19.77% -23.96% 34.72% 18.97% -753.09% 23.91% -2.99% 42.82% -118.22% 21.85% 38.22% 291.28% 117.14% 45.44% 113.62% -45.50% 59.89% 168.64% -223.20% 159.91%          
      qoq
    241.88% -46.73% 32.36% 7326.77% -100.84% 25.16% 0.78% -52.06% -31.67% -270.63% -156.52% 9.39% -21.76% -20.13% -2.43% 31.59% -25.85% 41.51% -13.84% -822.37% -114.07% 10.79% 26.85% -7.84% -5.92% 25.67% 259.10% -48.86% -36.98% 84.58% -8.38% 50.04% 5.88% -184.65% -293.28%       
      net income margin %
    15.02% 4.44% 8.84% 7.17% 0.11% -13.47% -12.12% -12.96% -33.41% -57.94% 27.57% -64.03% -77.81% -117.16% -143.84% -167.30% -141.63% -273.70% -200.47% -320.24% 10.98% -472.18% -468.40% -512.41% -701.01% -681.81% -615.58% -35.32% -215.94% -454.59% -266.58% -298.68% -323.00% -546.27% 53.26% -Infinity% NaN% NaN% NaN% NaN%  
      earnings per share
                                             
      basic
    0.16 0.04 0.09 0.07  -0.09 -0.09   -0.095 0.16          0.06                     
      diluted
    0.15 0.04 0.08 0.06  -0.09 -0.09   -0.095 0.15          0.05                     
      weighted-average shares outstanding—basic
    1,442,451,870 1,417,803,727 1,432,801,699 1,408,166,754 1,390,052,966  1,376,751,873    1,360,716,279      1,332,017,262    1,188,943,726                     
      weighted-average shares outstanding—diluted
    1,505,027,338 1,474,829,908 1,488,750,354 1,463,277,401 1,445,253,219  1,376,751,873    1,390,331,833      1,332,017,262    1,257,489,671                     
      earnings per american depositary share
                                             
      basic
    2.05 0.6 1.13 0.87 0.01 -1.178 -1.15   -1.23 2.06          0.73                     
      diluted
    1.96 0.57 1.09 0.84 0.01 -1.178 -1.15   -1.23 2.01          0.69                     
      weighted-average adss outstanding—basic
    110,957,836 109,061,825 110,215,515 108,320,520 106,927,151  105,903,990    104,670,483      102,462,866    91,457,210                     
      weighted-average adss outstanding—diluted
    115,771,334 113,448,454 114,519,258 112,559,800 111,173,325  105,903,990    106,948,603      102,462,866    96,729,975                     
      collaboration revenue
       13,224,000 8,749,000 9,789,000 8,152,000 8,020,000 4,734,000 3,883,000 186,018,000 41,516,000 37,510,000 41,073,000 38,122,000 37,061,000 45,053,000 17,194,000 13,979,000 11,368,000 499,755,000       185,204,000 20,412,000 20,908,000 15,755,000 21,378,000 9,294,000 2,568,000 211,391,000    393,000 677,000  
      amortization of intangible assets
             1,838,000 1,287,000 188,000 187,000 188,000 187,000 188,000 188,000 187,000 188,000 187,000 188,000 188,000 187,000 188,000 283,000 -332,000 -331,000 -332,000 -331,000 -331,000 -188,000 -187,000 -188,000 -187,000 -63,000       
      other expense
           -11,984,000    -63,818,000    -129,617,000                          
      net income per share
           -0.09 -0.19   -0.28 -0.26 -0.33 -0.41 -0.43      -0.4 -0.37 -0.33 -0.36 -0.5 -0.39 -0.11 -0.22             
      weighted-average shares outstanding—basic and diluted
         1,368,746,793  1,361,082,567 1,355,547,626 1,357,034,547  1,360,224,377 1,354,164,760  1,345,303,747 1,336,463,026   1,205,971,284 1,194,071,476                      
      net loss per american depositary share (“ads”), basic and diluted
           -1.15 -2.41             -5.25 -4.81 -4.31 -4.7 -6.43 -5.11 -1.43 -2.81             
      weighted-average adss outstanding—basic and diluted
         105,288,215  104,698,659 104,272,894 104,387,273  104,632,644 104,166,520  103,484,904 102,804,848   92,767,022 91,851,652                      
      expenses
                                             
      total expenses
             662,077,750 915,276,000 913,976,000 819,059,000 848,717,000 825,985,000 780,971,000 749,913,000 785,718,000 668,765,000 624,830,000 535,705,000 585,012,000 531,217,000 424,512,000 425,815,000 -444,929,000 -362,407,000 -329,179,000 -251,588,000 -339,478,000 -205,304,000 -215,854,000 -143,353,000 -121,972,000 -105,308,000       
      net loss per american depositary share
               -3.64 -3.34 -3.785 -5.39 -5.56                          
      net income per share
           -0.09 -0.19   -0.28 -0.26 -0.33 -0.41 -0.43      -0.4 -0.37 -0.33 -0.36 -0.5 -0.39 -0.11 -0.22             
      basic
                    -0.33             -0.145 -0.19   0.003 0.21       
      diluted
                    -0.33             -0.145 -0.19   0.003 0.2       
      net income per american depositary share
                                             
      income tax benefit
                     -6,020,750 -19,223,000   -2,086,000 -8,423,000   -7,561,000 3,217,000 -2,129,000 -519,000 8,544,000 472,000 3,368,000 3,412,000 670,000 3,061,000       
      less: net loss attributable to noncontrolling interests
                         96,000 -1,393,000 -1,116,000 -1,204,000 166,000 -1,303,000 -384,000 -429,000 1,545,000 -461,000 -828,000 -520,000         
      net loss attributable to beigene, ltd.
                     -585,653,000 -413,855,000 -480,341,000  -472,745,000 -425,224,000 -335,202,000 -363,735,000 -388,061,000 -307,357,000 -85,570,000 -167,640,000   -156,887,000 -104,596,000   -60,545,000      
      loss per share attributable to beigene, ltd.
                     -0.173 -0.34 -0.4                      
      loss per american depositary share
                     -2.248 -4.46 -5.23                      
      net income attributable to beigene, ltd.
                        66,495,000         -101,378,500 -144,031,000   1,554,500 117,386,000       
      earnings per share attributable to beigene, ltd.
                                             
      basic
    0.16 0.04 0.09 0.07  -0.09 -0.09   -0.095 0.16          0.06                     
      diluted
    0.15 0.04 0.08 0.06  -0.09 -0.09   -0.095 0.15          0.05                     
      weighted-average shares outstanding, basic and diluted
                 1,340,729,572    1,206,210,049    1,085,131,783 1,148,973,077 1,010,230,470 1,005,347,581 780,701,283 781,482,459 777,509,102 774,750,255 720,753,819            
      weighted-average adss outstanding, basic and diluted
                 103,133,044    92,785,388    83,471,676 88,382,544 77,710,036 77,334,429 60,053,945 60,114,035 59,808,392 59,596,173 55,442,601            
      income before income tax expense
                                 -103,643,750 -144,964,000   825,250 114,223,000       
      weighted-average shares used for eps calculation
                                             
      basic
                                  739,789,269    547,546,656       
      diluted
                                  739,789,269    600,612,680       
      weighted-average adss used in net income per share calculation
                                             
      loss before income tax expense
                                   -161,083,000 -108,528,000   -60,479,000      
      net income per share
           -0.09 -0.19   -0.28 -0.26 -0.33 -0.41 -0.43      -0.4 -0.37 -0.33 -0.36 -0.5 -0.39 -0.11 -0.22             
      basic and diluted
                                   -0.22 -0.16         
      weighted-average shares used for eps calculation
                                             
      basic and diluted
                                   698,506,891 670,510,605 543,185,460  517,663,736 516,437,707 428,137,509 427,746,711 294,042,572  
      net loss per american depositary share
               -3.64 -3.34 -3.785 -5.39 -5.56                          
      basic and diluted
                                   -2.92 -2.03         
      weighted-average adss used in net loss per share calculation
                                             
      revenue
                                             
      changes in fair value of financial instruments
                                             
      gain on sale of available-for-sale securities
                                     34,000  2,000 8,000     
      less: net loss attributable to noncontrolling interest
                                     -59,250 -102,000 -135,000      
      total revenue
                                          393,000 677,000  
      operating expenses:
                                             
      general and administrative
                                       -10,777,000      
      loss per share
                                             
      basic and diluted
                                       -0.12      
      weighted-average number of ordinary shares used in net loss per share calculation
                                             
      basic and diluted
                                   698,506,891 670,510,605 543,185,460  517,663,736 516,437,707 428,137,509 427,746,711 294,042,572  
      loss per american depositary share
                     -2.248 -4.46 -5.23                      
      basic and diluted
                                       -1.52      
      loss per ads
                                             
      basic and diluted
                                             
      disposal loss on available-for-sale securities
                                             
    Balance Sheets:
    Quarterly
    Annual
      Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 
                                               
        assets
                                               
        current assets:
                                               
        cash and cash equivalents
      4,791,676,000 4,547,530,000 4,036,868,000 2,756,056,000 2,516,411,000 2,627,410,000 2,701,933,000 2,592,655,000 2,793,370,000 3,171,800,000 3,067,336,000 3,410,368,000 3,538,644,000 3,869,564,000 4,197,132,000 4,531,137,000 4,347,162,000 4,375,678,000 1,383,310,000 1,776,448,000 1,901,819,000 1,381,950,000 1,464,470,000 1,345,014,000 1,957,101,000 618,011,000 856,151,000 918,948,000 764,492,000 712,937,000 643,485,000 438,420,000 490,634,000 239,602,000 208,510,000 261,006,000 97,750,000 85,532,000 58,084,000 208,506,000  
        accounts receivable
      938,019,000 865,080,000 863,281,000 770,776,000 717,239,000 676,278,000 569,047,000 529,449,000 435,294,000 358,027,000 309,079,000 299,282,000 309,628,000 173,168,000 189,170,000 172,259,000 190,800,000 483,113,000 129,584,000 73,787,000 84,010,000 60,403,000 60,266,000 61,663,000 65,620,000 70,878,000 55,912,000 58,108,000 58,976,000 41,056,000 37,372,000 33,171,000 23,485,000 29,428,000 10,521,000       
        inventories
      681,590,000 608,227,000 531,687,000 502,867,000 494,660,000 494,986,000 431,676,000 443,260,000 447,345,000 416,122,000 316,929,000 321,333,000 296,995,000 282,346,000 290,911,000 262,210,000 245,628,000 242,626,000 150,979,000 117,587,000 72,974,000 89,293,000 35,525,000 33,234,000 28,775,000 28,553,000 37,512,000 49,048,000 13,140,000 16,242,000 19,699,000 6,322,000 7,498,000 10,930,000 5,712,000       
        prepaid expenses and other current assets
      189,995,000 212,752,000 232,641,000 280,522,000 168,182,000 192,919,000 209,080,000 273,658,000 231,741,000 243,392,000 241,661,000 255,050,000 264,835,000 216,553,000 199,766,000 207,383,000 266,436,000 270,173,000 235,015,000 225,455,000 171,399,000 160,012,000 150,880,000 144,466,000 126,312,000 90,238,000 95,936,000 96,206,000 89,941,000 81,942,000 69,925,000 63,293,000 49,382,000 35,623,000 17,712,000 11,261,000 8,702,000 6,335,000 6,135,000 4,556,000  
        total current assets
      6,601,280,000 6,233,589,000 5,664,477,000 4,310,221,000 3,896,492,000 3,991,593,000 3,911,736,000 3,839,022,000 3,907,750,000 4,203,414,000 4,053,542,000 4,401,419,000 4,704,318,000 5,207,078,000 5,749,168,000 6,345,876,000 6,948,139,000 7,613,880,000 4,432,835,000 4,799,039,000 5,140,979,000 4,960,690,000 4,965,736,000 3,392,404,000 3,595,187,000 1,172,696,000 1,435,550,000 1,755,680,000 1,796,730,000 1,943,842,000 2,180,195,000 1,516,707,000 1,585,702,000 913,497,000 962,330,000 418,691,000 336,178,000 209,953,000 232,754,000 251,782,000  
        property, plant and equipment
      1,640,918,000 1,641,678,000 1,628,114,000 1,615,792,000 1,598,588,000 1,578,423,000 1,562,965,000 1,516,491,000 1,417,992,000 1,324,154,000 1,178,038,000 1,031,938,000 925,404,000 845,946,000 681,914,000 633,100,000 624,673,000 587,605,000 450,788,000 395,167,000 373,949,000 357,686,000 291,218,000 258,106,000 240,331,000  226,499,000 212,672,000 197,806,000             
        operating lease right-of-use assets
      145,497,000 148,184,000 140,217,000 145,769,000 146,416,000 139,309,000 101,046,000 103,633,000 87,747,000 95,207,000 98,742,000 99,422,000 108,989,000 109,960,000 110,340,000 117,583,000 115,497,000 117,431,000 100,585,000 95,980,000 86,946,000 90,581,000 88,689,000 90,620,000 91,509,000 82,520,000 75,339,000 74,640,000 72,624,000             
        intangible assets
      61,681,000 62,704,000 63,581,000 64,890,000 50,139,000 51,095,000 53,939,000 53,715,000 55,171,000 57,138,000 53,657,000 46,895,000 39,735,000 40,616,000 40,849,000 43,325,000 45,807,000 46,679,000 14,104,000 12,008,000 4,813,000 5,000,000 5,188,000 5,375,000 5,563,000 5,846,000 6,178,000 6,509,000 6,841,000 7,172,000 7,299,000 6,875,000 7,062,000 7,250,000 7,437,000       
        other non-current assets
      104,243,000 102,418,000 136,197,000 161,722,000 149,891,000 160,490,000 201,174,000 199,318,000 199,021,000 125,362,000 140,900,000 147,549,000 173,366,000 170,413,000 140,553,000 130,955,000 164,554,000 163,049,000 175,122,000 132,244,000 127,820,000 113,090,000 162,600,000 112,382,000 94,250,000 68,455,000 64,848,000 60,158,000 58,605,000 53,668,000 28,908,000 11,452,000 14,210,000 42,915,000 2,051,000 16,687,000 6,900,000 8,918,000 8,724,000 5,744,000  
        total non-current assets
      1,952,339,000 1,954,984,000 1,968,109,000 1,988,173,000 1,945,034,000 1,929,317,000 1,919,124,000 1,873,157,000 1,759,931,000 1,601,861,000 1,471,337,000 1,327,317,000 1,252,457,000 1,172,212,000 976,845,000 1,032,331,000 1,073,249,000 1,032,069,000 853,499,000 725,077,000 680,025,000 640,067,000 600,654,000 510,886,000 472,025,000 439,593,000 445,520,000 394,638,000 375,502,000 305,842,000 228,432,000 137,149,000 123,225,000 132,982,000 86,729,000 55,284,000 40,551,000 25,472,000 18,476,000 13,446,000  
        total assets
      8,553,619,000 8,188,573,000 7,632,586,000 6,298,394,000 5,841,526,000 5,920,910,000 5,830,860,000 5,712,179,000 5,667,681,000 5,805,275,000 5,524,879,000 5,728,736,000 5,956,775,000 6,379,290,000 6,726,013,000 7,378,207,000 8,021,388,000 8,645,949,000 5,286,334,000 5,524,116,000 5,821,004,000 5,600,757,000 5,566,390,000 3,903,290,000 4,067,212,000 1,612,289,000 1,881,070,000 2,150,318,000 2,172,232,000 2,249,684,000 2,408,627,000 1,653,856,000 1,708,927,000 1,046,479,000 1,049,059,000 473,975,000 376,729,000 235,425,000 251,230,000 265,228,000  
        liabilities and shareholders’ equity
                                               
        current liabilities:
                                               
        accounts payable
      423,546,000 479,035,000 383,676,000 360,783,000 364,498,000 404,997,000 307,532,000 333,022,000 356,575,000 315,111,000 341,857,000 266,975,000 241,360,000 294,781,000 252,071,000 234,355,000 236,915,000 262,400,000 206,203,000 168,826,000 146,923,000 231,957,000 146,265,000 157,173,000 98,364,000 122,488,000 112,282,000 148,536,000 105,320,000 113,283,000 85,552,000 85,878,000 52,719,000 69,779,000 35,168,000 24,419,000 20,482,000 7,307,000 6,071,000 3,823,000  
        accrued expenses and other payables
      1,079,283,000 1,109,120,000 1,001,661,000 908,882,000 692,179,000 803,713,000 717,343,000 646,538,000 569,438,000 693,731,000 505,824,000 454,950,000 417,922,000 467,352,000 410,255,000 454,183,000 385,976,000 558,055,000 389,874,000 398,856,000 312,134,000 346,144,000 279,323,000 207,921,000 179,331,000 163,556,000 133,020,000 103,061,000 90,737,000 100,414,000 75,882,000 75,037,000 55,712,000 49,598,000 46,991,000 22,427,000 24,463,000 21,715,000 14,226,000 11,577,000  
        tax payable
      63,522,000 41,625,000 11,219,000 5,536,000 34,144,000 25,930,000 14,880,000 5,278,000 27,324,000 22,951,000 20,158,000 17,074,000 33,929,000 25,189,000 22,665,000 15,564,000 38,505,000 21,395,000 20,878,000 13,855,000 27,463,000 20,380,000 9,244,000 10,448,000 19,535,000 13,454,000 9,061,000 2,175,000 6,857,000 5,888,000 1,549,000 1,151,000 9,889,000 9,156,000 2,852,000 3,106,000 2,570,000 294,000 168,000 33,000  
        operating lease liabilities, current portion
      20,584,000 20,698,000 15,732,000 17,250,000 18,303,000 17,576,000 17,707,000 17,658,000 19,401,000 21,950,000 23,246,000 23,508,000 24,545,000 24,041,000 24,340,000 24,788,000 22,894,000 21,925,000 18,644,000 16,550,000 13,993,000 13,895,000 13,280,000 12,888,000 14,597,000 10,814,000                
        research and development cost share liability, current portion
      35,700,000 64,345,000 90,596,000 108,992,000 111,127,000 111,154,000 104,067,000 84,615,000 81,986,000 68,004,000 63,652,000 62,516,000 69,510,000 114,335,000 115,721,000 125,394,000 120,971,000 120,801,000 153,838,000 145,820,000 135,333,000 127,808,000 147,387,000 136,704,000 128,672,000                 
        sale of future royalty liability, current portion
      72,735,000 56,714,000 52,245,000                                       
        short-term debt
      116,140,000 57,293,000 813,296,000 808,394,000 763,470,000 851,529,000 863,803,000 851,657,000 826,965,000 688,366,000 328,560,000 421,052,000 281,808,000 328,969,000 441,275,000 380,729,000 407,387,000 427,565,000 442,372,000 434,802,000 405,045,000 335,015,000 50,222,000                   
        total current liabilities
      1,811,510,000 1,828,830,000 2,368,425,000 2,209,837,000 1,983,721,000 2,214,899,000 2,025,332,000 1,938,768,000 1,881,689,000 1,810,113,000 1,283,297,000 1,405,109,000 1,254,551,000 1,468,528,000 1,411,311,000 1,398,409,000 1,376,306,000 1,599,555,000 1,304,435,000 1,242,314,000 1,112,542,000 1,075,199,000 645,721,000 551,195,000 451,797,000 310,312,000 265,734,000 271,679,000 238,809,000 246,452,000 188,424,000 186,435,000 141,896,000 149,988,000 103,161,000 49,952,000 49,985,000 29,316,000 20,465,000 15,826,000  
        non-current liabilities:
                                               
        long-term debt
      962,515,000 961,913,000 139,571,000 146,091,000 160,157,000 166,484,000    197,618,000    209,148,000    202,113,000     151,551,000                   
        sale of future royalty liability, non-current portion
      831,664,000 850,242,000 832,755,000                                       
        operating lease liabilities, non-current portion
      49,670,000 52,940,000 51,387,000 53,940,000 54,895,000 44,277,000 32,454,000 35,398,000 17,722,000 22,251,000 25,474,000 25,821,000 32,543,000 34,517,000 36,904,000 41,921,000 39,989,000 43,041,000 37,613,000 34,172,000 26,565,000 29,417,000 28,679,000 31,165,000 32,967,000 25,833,000                
        deferred tax liabilities
      55,866,000 53,209,000 47,066,000 44,093,000 43,110,000 42,007,000 15,935,000 15,942,000 16,437,000 16,494,000 16,358,000 15,652,000 16,061,000 15,996,000 15,249,000 14,739,000 14,219,000 14,169,000 13,266,000 12,270,000 10,794,000 10,792,000 11,884,000 11,379,000 10,368,000 10,532,000 10,681,000 11,802,000 11,333,000 11,139,000     1,859,000       
        other long-term liabilities
      81,952,000 80,245,000 64,056,000 63,079,000 65,629,000 66,735,000 50,568,000 51,533,000 48,901,000 50,510,000 41,986,000 43,118,000 45,619,000 46,095,000 45,169,000 48,432,000 51,828,000 54,234,000 54,606,000 55,331,000 55,320,000 57,429,000 47,890,000 46,514,000 45,305,000 46,562,000 36,580,000 38,101,000 38,972,000 38,931,000 34,879,000 21,772,000 22,902,000 31,959,000 744,000 1,123,000 893,000 247,000 165,000 89,000  
        total non-current liabilities
      1,981,667,000 1,998,549,000 1,134,835,000 318,082,000 358,292,000 373,789,000 369,455,000 407,156,000 425,631,000 457,835,000 478,348,000 525,068,000 544,918,000 527,407,000 659,531,000 677,254,000 759,582,000 803,407,000 624,826,000 675,027,000 704,875,000 656,315,000 624,155,000 805,603,000 788,359,000 323,622,000 321,099,000 307,375,000 310,744,000 249,585,000 236,772,000 240,753,000 208,309,000 212,260,000 181,409,000 153,851,000 18,327,000 18,277,000 10,718,000 6,303,000  
        total liabilities
      3,793,177,000 3,827,379,000 3,503,260,000 2,527,919,000 2,342,013,000 2,588,688,000 2,394,787,000 2,345,924,000 2,307,320,000 2,267,948,000 1,761,645,000 1,930,177,000 1,799,469,000 1,995,935,000 2,070,842,000 2,075,663,000 2,135,888,000 2,402,962,000 1,929,261,000 1,917,341,000 1,817,417,000 1,731,514,000 1,269,876,000 1,356,798,000 1,240,156,000 633,934,000 586,833,000 579,054,000 549,553,000 496,037,000 425,196,000 427,188,000 350,205,000 362,248,000 284,570,000 203,803,000 68,312,000 47,593,000 31,183,000 22,129,000  
        commitments and contingencies
                                               
        shareholders’ equity:
                                               
        ordinary shares, 0.0001 par value per share...
      144,000 144,000 144,000 143,000 140,000 138,000 138,000 137,000 136,000 135,000    135,000    133,000    118,000    79,000    77,000            
        additional paid-in capital
      12,906,326,000 12,759,137,000 12,616,844,000 12,395,276,000 12,247,260,000 12,087,908,000 11,974,415,000 11,840,197,000 11,705,069,000 11,598,688,000 11,502,527,000 11,752,019,000 11,644,957,000 11,540,979,000 11,451,566,000 11,356,686,000 11,268,290,000 11,191,007,000 7,724,822,000 7,561,155,000 7,486,518,000 7,414,932,000 7,367,799,000 5,200,275,000 5,138,239,000 2,925,970,000 2,861,012,000 2,814,449,000 2,777,474,000 2,744,814,000 2,710,053,000 1,804,942,000 1,782,033,000 1,000,747,000 981,237,000 604,603,000 597,268,000 388,568,000 385,787,000 384,502,000 208,889,000 
        accumulated other comprehensive loss
      -53,482,000 -78,184,000 -101,257,000 -113,698,000 -142,321,000 -148,988,000 -83,525,000 -140,474,000 -131,644,000 -99,446,000 -144,931,000 -143,687,000 -59,014,000          -419,000 -9,299,000 -6,548,000      -724,000   -480,000  -322,000      
        accumulated deficit
      -8,092,546,000 -8,319,903,000 -8,386,405,000 -8,511,246,000 -8,605,566,000 -8,606,836,000 -8,454,955,000 -8,333,605,000 -8,213,200,000 -7,962,050,000 -7,594,497,000 -7,809,910,000 -7,428,773,000 -7,080,342,000 -6,635,007,000 -5,971,826,000 -5,400,377,000 -4,966,103,000 -4,380,450,000 -3,966,595,000 -3,486,254,000 -3,552,749,000 -3,080,004,000 -2,654,780,000 -2,319,578,000 -1,955,843,000 -1,567,782,000 -1,260,425,000 -1,174,855,000 -1,007,215,000 -738,960,000 -594,929,000 -438,042,000 -330,517,000 -231,194,000 -348,580,000      
        total shareholders’ equity
      4,760,442,000 4,361,194,000 4,129,326,000 3,770,475,000 3,499,513,000 3,332,222,000 3,436,073,000 3,366,255,000 3,360,361,000 3,537,327,000                           308,417,000     
        total liabilities and shareholders’ equity
      8,553,619,000 8,188,573,000 7,632,586,000 6,298,394,000 5,841,526,000 5,920,910,000 5,830,860,000 5,712,179,000 5,667,681,000 5,805,275,000                           376,729,000     
        research and development cost share liability, non-current portion
         10,879,000 34,501,000 54,286,000 82,985,000 119,012,000 143,544,000 170,662,000 191,739,000 208,775,000 207,052,000 179,625,000 204,252,000 219,385,000 247,572,000 269,561,000 266,163,000 303,126,000 340,585,000 375,040,000 384,151,000 424,890,000 460,528,000                 
        long-term bank loans
            187,513,000 185,271,000 199,027,000  202,491,000 207,426,000 206,298,000  208,058,000 185,207,000 201,605,000  200,906,000 194,856,000 193,017,000 183,637,000                    
        short-term investments
               2,600,000 106,989,000 105,693,000 294,057,000 665,251,000 871,998,000 1,172,554,000 1,897,783,000 2,241,962,000 2,533,617,000 2,605,452,000 2,910,472,000 3,268,725,000 3,254,300,000 1,807,744,000 1,417,097,000 364,728,000 375,768,000 618,803,000 849,167,000 1,068,509,000 1,390,276,000 931,208,000 973,381,000 597,914,000 548,925,000 146,424,000 229,726,000 118,086,000 168,535,000 38,720,000  
        short-term restricted cash
               11,473,000 11,548,000 9,693,000 159,000 196,000 191,000 333,000 330,000 328,000 330,000 310,000 305,000 307,000 295,000 283,000 282,000 288,000 14,271,000 14,567,000 14,900,000 14,544,000            
        deferred revenue, current portion
                 159,034,000 185,477,000 213,861,000 144,984,000 163,396,000 163,658,000 187,414,000 72,626,000 63,605,000 71,651,000        17,504,000 18,140,000  15,302,000 14,011,000 12,233,000 9,132,000       
        deferred revenue, non-current portion
               300,000 300,000 24,276,000 37,345,000 42,026,000 149,899,000 167,570,000 204,369,000 220,289,000 52,272,000 75,272,000 78,594,000        8,240,000 9,842,000  18,297,000 21,291,000 24,808,000 29,477,000       
        liabilities and shareholders' equity
                                               
        shareholders' equity:
                                               
        ordinary shares, us0.0001 par value per share...
                135,000 137,000 136,000  135,000 134,000 133,000  121,000 120,000 119,000  118,000 102,000 101,000  78,000 78,000 78,000  77,000           
        total shareholders' equity
                3,763,234,000                               
        total liabilities and shareholders' equity
                5,524,879,000                               
        long-term restricted cash
                 1,513,000 4,963,000 5,277,000 3,189,000 3,939,000 6,958,000 6,881,000 6,056,000 9,927,000 8,282,000 7,748,000 4,950,000 4,602,000 2,435,000 2,476,000 30,401,000 9,161,000 8,991,000 13,232,000            
        equity:
                                               
        total equity
                 3,798,559,000 4,157,306,000 4,383,355,000 4,655,171,000 5,302,544,000 5,885,500,000 6,242,987,000 3,357,073,000 3,606,775,000 4,003,587,000 3,869,243,000 4,296,514,000 2,546,492,000 2,827,056,000 978,355,000 1,294,237,000 1,571,264,000 1,622,679,000 1,753,647,000 1,983,431,000 1,226,668,000 1,358,722,000 684,231,000 764,489,000 270,172,000      
        total liabilities and equity
                 5,728,736,000 5,956,775,000 6,379,290,000 6,726,013,000 7,378,207,000 8,021,388,000 8,645,949,000 5,286,334,000 5,524,116,000 5,821,004,000 5,600,757,000 5,566,390,000 3,903,290,000 4,067,212,000 1,612,289,000 1,881,070,000 2,150,318,000 2,172,232,000 2,249,684,000 2,408,627,000 1,653,856,000 1,708,927,000 1,046,479,000 1,049,059,000 473,975,000      
        accumulated other comprehensive income
                   -77,417,000 -161,523,000 -82,450,000 17,454,000 17,950,000 12,580,000 12,095,000 3,204,000 6,942,000    -8,001,000 -14,830,000 -225,000 6,072,000 1,526,000  3,114,000 320,000  38,000       
        deferred tax assets
                     103,429,000 115,760,000 110,424,000 106,844,000 79,751,000 78,215,000 65,962,000 48,009,000 39,801,000 37,937,000 37,894,000 42,146,000 31,389,000 30,526,000 29,542,000 16,474,000 16,071,000 11,991,000 7,675,000 7,684,000 4,827,000 2,928,000     
        shareholder loan
                             160,164,000 157,278,000 157,384,000 150,758,000 154,321,000 155,174,000 148,888,000 146,409,000 149,217,000 154,551,000 146,271,000 140,311,000 135,027,000      
        total beigene, ltd. shareholders’ equity
                           3,869,243,000 4,287,494,000 2,536,298,000 2,812,214,000 962,205,000 1,278,478,000 1,553,877,000 1,608,769,000 1,739,202,000 1,970,446,000 1,213,197,000 1,344,381,000 669,809,000 750,140,000 255,753,000      
        noncontrolling interest
                            9,020,000 10,194,000 14,842,000 16,150,000 15,759,000 17,387,000 13,910,000 14,445,000 12,985,000 13,471,000 14,341,000 14,422,000 14,349,000 14,419,000      
        short-term bank loans
                             26,061,000                  
        long-term bank loan
                             131,491,000 81,913,000  104,233,000 84,489,000 77,480,000 40,785,000 40,824,000 51,467,000 9,565,000 9,222,000 9,018,000 17,701,000 17,434,000 18,030,000 10,553,000 6,214,000  
        short-term bank loan
                              11,298,000                 
        property and equipment
                               242,402,000    157,061,000 111,262,000 90,510,000 76,990,000 62,568,000 55,322,000 33,770,000 30,723,000 16,554,000 9,752,000 7,702,000  
        land use right
                                   45,058,000 11,629,000 12,132,000 12,863,000 12,465,000 12,251,000       
        long-term bank loans, current portion
                                               
        long-term bank loans, non-current portion
                               83,311,000                
        unbilled receivable
                                  6,114,000 8,612,000 4,878,000 12,702,000 23,862,000  170,950,000       
        goodwill
                                109,000 109,000 109,000 109,000 109,000 109,000 109,000 109,000 1,984,000       
        current portion of operating lease liabilities
                                10,671,000 9,167,000 9,451,000             
        current portion of long-term bank loan
                                700,000 8,740,000 8,940,000 8,727,000 8,736,000 9,067,000 9,565,000 9,222,000 9,018,000       
        operating lease liabilities
                                18,847,000 18,662,000 19,545,000             
        restricted cash, current
                                    14,560,000           
        restricted cash, non-current
                                    52,751,000           
        deferred revenue, current
                                    16,705,000           
        deferred revenue, non-current
                                    14,660,000           
        restricted cash
                                     31,591,000 17,460,000         
        ordinary shares
                                     70,000 70,000 59,000 59,000 52,000 52,000 43,000 43,000 43,000 32,000 
        short-term loan
                                          2,470,000     
        liabilities and shareholders’ deficit
                                               
        advances from customers
                                             393,000  
        senior promissory note
                                               
        warrant and option liabilities
                                               
        deferred rental
                                               
        convertible preferred shares
                                               
        series a
                                               
        total mezzanine equity
                                               
        shareholders’ deficit:
                                               
        total shareholders’ (deficit) equity
                                           187,832,000 220,047,000 243,099,000 88,917,000 
        total liabilities, mezzanine equity and shareholders’ (deficit) equity
                                           235,425,000 251,230,000 265,228,000 116,764,000 
                                               
      Cashflow Statements:
      Quarterly
      Annual
        Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-09-30 2016-06-30 2016-03-31 
                                                
          operating activities:
                                                
          net income
        227,357,000 66,502,000 124,841,000 94,320,000 1,270,000            -434,274,000    66,495,000                    
          adjustments to reconcile net income to net cash from operating activities:
                                                
          depreciation and amortization expense
        41,144,000 35,984,000 37,284,000 35,614,000 32,804,000 50,246,000 71,292,000 24,931,000 25,293,000 23,819,000 21,510,000 22,335,000 20,011,000 18,016,000 16,201,000 15,461,000 16,600,000 13,121,000 12,177,000 11,527,000 9,632,000 7,828,000 8,344,000 7,867,000 7,750,000 7,484,000 4,022,000 3,695,000 3,416,000 3,363,000 2,445,000 2,336,000 2,244,000 2,054,000       
          share-based compensation expenses
        123,355,000  140,809,000 150,809,000 95,478,000  114,697,000 130,637,000 88,667,000  96,004,000 103,371,000 75,322,000  78,176,000 81,305,000 65,555,000  67,077,000 64,791,000 45,833,000  50,297,000 45,468,000 38,255,000  36,818,000 32,602,000 26,392,000 25,958,000 25,132,000 18,641,000 17,396,000     2,779,000 1,285,000 2,614,000 
          amortization of research and development cost share liability
        -28,645,000 -26,251,000 -29,275,000 -25,757,000 -19,812,000 -21,612,000 -16,575,000 -21,903,000 -13,136,000 -16,725,000 -15,900,000 -5,271,000 -17,398,000 -26,013,000 -24,806,000 -23,764,000 -21,819,000 -29,640,000 -28,944,000 -26,972,000 -26,930,000 -28,690,000 -30,056,000 -27,606,000 -27,634,000                
          non-cash interest expense
        21,096,000                       2,534,000 2,572,000 2,570,000 1,717,000 1,901,000 1,858,000 1,856,000 1,849,000 2,103,000 2,012,000 2,239,000 2,564,000      
          other items
        6,172,000 -12,548,000 -5,533,000 2,759,000 12,369,000 -353,000 6,103,000 4,565,000 848,000 -6,820,000 55,000 192,000 575,000 1,285,000 1,402,000 2,816,000 3,544,000 5,791,000 6,507,000 5,949,000 5,263,000 5,490,000 2,007,000 242,000 -1,105,000                
          changes in operating assets and liabilities:
                                                
          accounts receivable
        -75,300,000 2,340,000 -93,925,000 -41,503,000 -31,866,000 -125,699,000 -29,848,000 -93,871,000 -80,025,000 -44,795,000 -11,588,000 4,564,000 -136,487,000 19,395,000 -22,713,000 14,876,000 292,554,000 -353,845,000 -55,836,000 10,318,000 -23,656,000 -134,000 1,403,000 5,858,000 3,236,000 -14,966,000 2,196,000 868,000 -17,920,000 -3,684,000 -4,201,000 -9,686,000 5,943,000 -18,907,000       
          inventories
        -71,838,000 -70,506,000 -28,836,000 2,187,000 3,987,000 -79,384,000 23,837,000 1,315,000 -37,264,000 -88,577,000 1,227,000 -40,571,000 -13,027,000 18,943,000 -43,999,000 -28,631,000 -3,002,000 -91,647,000 -33,392,000 -44,613,000 16,319,000 -51,934,000 -2,291,000 -4,459,000 -222,000 8,959,000 11,536,000 -35,908,000 3,102,000 3,457,000 -13,377,000 1,176,000 3,432,000 -5,218,000       
          other assets
        15,270,000 -18,083,000 100,563,000 -75,053,000 29,737,000 35,621,000 41,738,000 -27,832,000 -4,401,000 29,718,000 13,029,000 19,781,000 -50,408,000 -33,607,000 -1,990,000 49,268,000 -16,953,000 -14,190,000 -15,734,000                      
          accounts payable
        -42,187,000 87,214,000 28,471,000 -4,284,000 -31,568,000 107,961,000 11,344,000 -44,108,000 46,300,000 -9,882,000 64,044,000 -10,089,000 -22,589,000 -8,555,000 34,565,000 4,662,000 -35,024,000 32,384,000 30,182,000 30,620,000 -73,178,000 73,856,000 -12,872,000 56,301,000 -21,450,000 10,375,000 -29,582,000 41,795,000 -20,364,000 17,893,000 -4,731,000 28,795,000 -18,487,000 33,878,000 8,178,000 4,768,000 8,474,000    
          accrued expenses and other payables
        -16,819,000 145,876,000 90,261,000 127,985,000 -52,360,000 56,716,000 82,894,000 51,053,000 -79,309,000 130,022,000 58,171,000 30,599,000 -38,681,000 43,999,000 -17,897,000 93,567,000 -74,042,000 139,225,000 -869,000 35,698,000 -34,010,000 66,821,000 71,401,000 28,696,000 15,775,000 30,536,000 29,959,000 12,325,000 -8,790,000 24,259,000 845,000 19,324,000 6,115,000 2,607,000 22,241,000 -2,036,000 2,166,000 7,489,000 2,649,000 3,222,000 
          other liabilities
        1,731,000 15,418,000 3,486,000 -3,979,000 4,043,000 -14,233,000 241,000 -186,000 -660,000 532,000 -33,000 -109,000 197,000 -1,376,000 2,281,000 -400,000 -1,714,000 -6,058,000 249,000                      
          net cash from operating activities
        201,336,000 417,347,000 402,553,000 263,598,000 44,082,000 75,160,000 188,369,000 -95,588,000 -308,572,000 -221,638,000 -78,150,000 -293,888,000 -563,777,000 -318,191,000 -561,906,000 -379,959,000 -236,563,000 -507,839,000 -495,713,000 -420,266,000 125,095,000 -332,334,000 -346,241,000 -262,942,000 -341,944,000 -267,181,000 -265,012,000 -46,101,000 -171,975,000 -193,894,000 -132,185,000 -117,137,000 -104,501,000 93,749,000 6,600,000      
          capital expenditures
        -40,789,000 -48,084,000 -43,826,000 -56,407,000 -133,655,000 -109,950,000 -156,578,000 -157,882,000 -121,470,000 -125,585,000 -108,655,000 -50,290,000 -45,131,000 -67,043,000 -38,531,000 -42,389,000 -28,681,000 -32,605,000 -21,533,000 -30,873,000 -21,447,000 -21,828,000 -23,254,000 -26,720,000 -10,613,000 -9,696,000 -18,933,000 -18,560,000      
          free cash flows
        160,547,000 417,347,000 354,469,000 219,772,000 -12,325,000 75,160,000 54,714,000 -205,538,000 -465,150,000 -221,638,000 -236,032,000 -415,358,000 -689,362,000 -318,191,000 -670,561,000 -430,249,000 -281,694,000 -507,839,000 -562,756,000 -458,797,000 82,706,000 -332,334,000 -374,922,000 -295,547,000 -363,477,000 -267,181,000 -295,885,000 -67,548,000 -193,803,000 -217,148,000 -158,905,000 -127,750,000 -114,197,000 74,816,000 -11,960,000      
          investing activities:
                                                
          purchases of property, plant and equipment
        -40,789,000  -48,084,000 -43,826,000 -56,407,000  -133,655,000 -109,950,000 -156,578,000  -157,882,000 -121,470,000 -125,585,000  -108,655,000 -50,290,000 -45,131,000  -67,043,000 -38,531,000 -42,389,000  -28,681,000 -32,605,000 -21,533,000  -30,873,000 -21,447,000 -21,828,000            
          proceeds from sale or maturity of investments
        27,000  1,800,000  2,655,000  19,000 190,538,000 376,962,000  301,370,000 720,000,000 331,028,000  760,876,000 890,515,000 1,107,000,000 778,467,000 975,366,000 740,499,000 256,743,000  384,537,000 456,893,000 710,598,000            
          purchase of in-process research and development
         -691,000 -60,000,000 -31,800,000    -48,665,000 -20,000,000 -75,000,000 -8,500,000 -20,000,000 -46,500,000 -43,000,000 -20,000,000 -20,000,000 -29,000,000 -60,000,000 -10,000,000        
          other investing activities
        -4,748,000 9,375,000 -499,000 -2,779,000 -7,334,000 17,881,000 -227,000 -1,082,000 -19,434,000    -9,250,000                           
          net cash from investing activities
        -45,510,000 -38,335,000 -49,274,000 -66,605,000 -121,941,000 -93,605,000 -133,882,000 -111,032,000 -209,831,000 -62,584,000 -186,275,000 67,800,000 241,063,000 38,536,000 169,484,000 658,710,000 210,393,000 109,110,000 -11,995,000 251,596,000 291,948,000 -86,925,000 -1,536,577,000 -429,895,000 -1,114,969,000 -23,892,000 213,630,000 192,009,000 172,416,000 213,243,000   -394,352,000 -68,242,000 -401,326,000      
          financing activities:
                                                
          repayment of long-term loan
        -7,641,000 -14,618,000 -4,263,000 -12,584,000 -4,215,000 -10,450,000 -3,561,000 -10,441,000 -3,579,000 -5,228,000   -1,457,000                           
          proceeds from short-term loans
        58,204,000 12,155,000 141,521,000 80,000,000 543,858,000 182,384,000 142,028,000 498,916,000 768,000   150,000,000 96,188,000 17,586,000 50,000,000 262,993,000 30,867,000 41,588,000 71,001,000                    
          repayment of short-term loans
         -768,999,000 -102,861,000 -172,921,000 -546,726,000   -150,000,000 -93,002,000 -16,574,000 -50,000,000 -271,653,000 -30,023,000 -42,258,000 -73,147,000 -281,525,000                       
          repayment of sale of future royalties liability
        -2,557,000                                        
          proceeds from option exercises and employee share purchase plan
        23,875,000 19,243,000 80,535,000 33,144,000 63,359,000 8,795,000 16,223,000 5,564,000 14,791,000 3,360,000 17,183,000 3,580,000 31,589,000 11,287,000 16,705,000 7,092,000 11,880,000 10,570,000 46,591,000 9,847,000 25,754,000 17,271,000 47,632,000 16,569,000 11,629,000 26,617,000 9,745,000 4,373,000 6,269,000            
          other financing activities
        -3,249,000                                      
          net cash from financing activities
        68,632,000 96,931,000 961,272,000 35,025,000 -33,777,000 -4,523,000 12,662,000 23,017,000 162,293,000 347,048,000 -76,782,000 166,080,000 -19,868,000 -110,366,000 120,242,000 -17,580,000 -11,267,000 3,384,654,000 109,207,000 35,631,000 107,419,000 325,658,000 1,994,007,000 80,993,000 2,802,168,000 2,198,000 25,136,000 15,382,000 42,964,000 8,803,000 871,250,000 46,583,000 763,901,000 3,048,000 339,708,000      
          effect of foreign exchange rate changes
        19,320,000 23,162,000 9,905,000 23,477,000 3,480,000 -51,713,000 28,348,000 -5,902,000 -22,438,000 42,266,000 525,000 -62,184,000 11,311,000 64,546,000 -62,717,000 -80,212,000 9,000,000 7,266,000 1,512,000 9,318,000 -4,061,000 13,891,000 8,627,000 1,925,000 -6,212,000 8,827,000 -15,607,000 -6,997,000 4,265,000 1,765,000 -7,644,000 -1,661,000 3,444,000 2,537,000 2,522,000     86,000 
          net increase in cash, cash equivalents, and restricted cash
        243,778,000 499,105,000 1,324,456,000             180,959,000 -28,437,000 2,993,191,000 -396,989,000 -123,721,000 520,401,000 -79,710,000 119,816,000 -609,919,000 1,339,043,000 -280,048,000 -41,853,000 154,293,000 47,670,000 29,917,000 240,785,000 -38,083,000 268,492,000        
          cash, cash equivalents, and restricted cash at beginning of period
        4,609,647,000  2,638,747,000  3,185,984,000  3,875,037,000  4,382,887,000  1,390,005,000  620,775,000  740,713,000           
          cash, cash equivalents, and restricted cash at end of period
        4,853,425,000  1,324,456,000 255,495,000 2,530,591,000  95,497,000 -189,505,000 2,807,436,000  -340,682,000 -122,192,000 3,543,766,000  -334,897,000 180,959,000 4,354,450,000  -396,989,000 -123,721,000 1,910,406,000  119,816,000 -609,919,000 1,959,818,000  -41,853,000 154,293,000 788,383,000  240,785,000          
          supplemental cash flow information:
                                                
          cash and cash equivalents
        4,791,676,000 510,662,000 1,280,812,000 239,645,000 2,516,411,000 -74,523,000 109,278,000 -200,715,000 2,793,370,000 104,464,000 -343,032,000 -128,276,000 3,538,644,000 -327,568,000 -334,005,000 183,975,000 4,347,162,000 2,992,368,000 -393,138,000 -125,371,000 1,901,819,000  119,456,000 -612,087,000 1,957,101,000  -62,797,000 154,456,000 764,492,000  205,065,000 -52,214,000 490,634,000        
          short-term restricted cash
        40,839,000 -11,703,000 37,185,000 4,469,000 11,333,000 28,000 -13,871,000 11,710,000 11,445,000 -75,000 1,855,000 9,534,000 159,000 5,000 -142,000 3,000 330,000 -2,000 20,000 5,000 305,000  12,000 1,000 282,000                
          long-term restricted cash
        20,910,000 146,000 6,459,000 11,381,000 2,847,000 -186,000 90,000 -500,000 2,621,000 703,000 495,000 -3,450,000 4,963,000 2,088,000 -750,000 -3,019,000 6,958,000 825,000 -3,871,000 1,645,000 8,282,000  348,000 2,167,000 2,435,000                
          income taxes (refunded)/paid
        -2,737,000                                        
          interest expense paid
        12,834,000  12,130,000 11,812,000 12,206,000  14,014,000 12,708,000 11,440,000                   1,202,000 888,000  879,000 336,000 331,000 320,000 322,000 313,000 305,000 268,000 134,000 108,000 
          supplemental non-cash information:
                                                
          capital expenditures included in accounts payable and accrued expenses
        43,249,000  -5,866,000 -2,087,000 60,010,000  -40,247,000 15,091,000 100,473,000  12,207,000 31,391,000 64,013,000                            
          rou assets obtained in exchange for new operating lease liabilities
        9,261,000  986,000 2,482,000 15,659,000                                    
          cash flows from operating activities:
                                                
          share-based compensation expense
                                          13,327,000 7,082,000 5,992,000    
          acquired in-process research and development
         191,000       31,800,000    48,665,000    30,000,000 45,000,000 8,500,000 20,000,000 46,500,000 43,000,000 20,000,000 20,000,000 29,000,000 60,000,000 10,000,000        
          impairment of equity investments
         41,410,000                                       
          loss on long-term investments
                                                
          deferred income tax expense
                                                
          gain on bms termination settlement
                                               
          deferred revenue
             156,000 261,000   -183,010,000 -39,511,000 -33,066,000 -38,996,000 -36,083,000 -37,061,000 -39,676,000 282,805,000 -13,979,000 -11,368,000 150,245,000     -25,744,000 -2,238,000 -3,383,000 -2,234,000 -1,703,000 -1,739,000 -1,568,000       
          cash flows from investing activities:
                                                
          purchases of property and equipment
                                     -23,254,000 -26,720,000 -10,613,000 -9,696,000 -18,933,000 -18,560,000      
          purchase of intangible assets
                                     -332,000           
          purchase of long-term investments
                                                
          proceeds from sale or maturity of short-term investments
                                                
          cash flows from financing activities:
                                                
          proceeds from sale of future royalties
         26,000,000                                       
          proceeds from long-term loan
             9,053,000 6,731,000      6,019,000 155,000 10,664,000       7,009,000 36,695,000       7,640,000   
          payments of debt issuance costs
                                                
          payments of withholding taxes from share-based awards
                                              
          cash, cash equivalents, and restricted cash, beginning of year
                                                
          cash, cash equivalents, and restricted cash, end of year
                                                
          supplemental cash flow disclosures:
                                                
          interest paid
                   4,998,000 5,017,000 5,304,000 6,966,000 6,282,000 6,617,000 6,569,000 9,131,000 7,340,000 6,927,000  38,223,000 2,218,000 1,136,000                
          supplemental non-cash activities:
                                                
          accruals for capital expenditures
                                                
          purchase of in-process research and development included in accounts payable
                                                
          purchase of intangible asset
             -4,674,000                                
          income taxes paid
          2,929,000 67,712,000 9,321,000 14,652,000 9,142,000 43,146,000 2,490,000 13,487,000 9,987,000 24,913,000 7,616,000 4,494,000 570,000 23,700,000 736,000 481,000 687,000 14,049,000 478,000  1,346,000 8,719,000 531,000  1,077,000 7,514,000 360,000  309,000 11,513,000 329,000 27,857,000 683,000 670,000 76,000 25,000 
          increase in equity investment from deconsolidation of a subsidiary
              40,798,000                                
          gain on deconsolidation of a subsidiary
               -3,735,000                               
          net decrease in cash, cash equivalents, and restricted cash
            -108,156,000 -74,681,000 95,497,000 -189,505,000 -378,548,000  -340,682,000 -122,192,000 -331,271,000                            
          net loss
             -151,881,000 -121,350,000 -120,405,000 -251,150,000 -367,553,000 215,413,000 -381,137,000 -348,431,000 -445,335,000 -552,757,000   -585,653,000 -413,855,000   -472,649,000 -426,617,000 -336,318,000 -364,939,000 -387,895,000 -308,660,000 -85,954,000 -168,069,000   -157,715,000 -105,116,000        
          adjustments to reconcile net loss to net cash from operating activities:
                                                
          unrealized losses on long-term investments
                                                
          acquired intangible asset included in accounts payable
                                                
          purchases of short-term investments
                                                
          proceeds from public offering, net of cost
                                                
          proceeds from sale of ordinary shares, net of cost
                            2,069,610,000 2,162,407,000               
          unrealized losses on equity investments
                  10,095,000 2,009,000 169,000 5,583,000 -7,116,000 6,555,000 16,974,000                        
          deferred income tax benefits
                  750,000 -51,000 36,000  -7,170,000 12,836,000 -5,286,000 -2,677,000 -26,097,000 -60,000 -12,251,000 -19,045,000 -7,702,000 -854,000 -206,000 4,102,000 -11,878,000 -473,000 -983,000 -13,150,000 -386,000 -4,323,000 -4,090,000 26,000 -1,812,000      
          purchases of investments
                  -3,999,000 -10,518,000 -1,064,000  -3,231,000 -11,000,000 -504,000  -705,828,000 -592,888,000 -764,163,000 -810,703,000 -2,436,762,000 -1,135,764,000 -1,307,179,000 -318,475,000 -140,034,000 -223,437,000 -487,354,000 -519,176,000 -917,588,000 -566,698,000 -632,224,000        
          proceeds from research and development cost share liability
                             616,834,000                
          payment to acquire joint venture (jv) minority interest
                                                
          acquisitions of equipment included in accounts payable
                      -11,366,000 -4,060,000 62,736,000 11,300,000 13,012,000 -2,021,000 30,906,000  1,964,000 2,550,000 26,412,000  -6,672,000 3,465,000 32,462,000  4,014,000 4,366,000 3,640,000 733,000 109,000 -831,000 2,204,000 241,000 -13,000 91,000 
          acquired in-process research and development included in accrued expenses
                                               
          unrealized gains on equity investments
                         9,534,000                       
          capital contribution from noncontrolling interest
                                            
          prepayment to acquire joint venture ("jv") minority interest
                                                
          repayment of short-term loan
                                              
          unrealized gains on equity method investments
                            3,327,000  1,290,000                  
          prepaid expenses and other current assets
                            -11,453,000 -12,587,000 1,649,000 -18,515,000 -36,075,000 14,310,000 270,000 -6,265,000 -8,270,000 -12,000,000 -6,633,000 -13,911,000 -13,758,000 -17,913,000 -5,931,000      
          other non-current assets
                            -6,495,000 15,291,000 -8,608,000 5,338,000 -2,710,000 -5,475,000 -5,014,000 -81,000 -10,212,000 -31,729,000 -4,805,000 -1,612,000 -2,082,000 -29,066,000 -496,000      
          tax payable
                            7,149,000 14,591,000 -9,266,000 -9,086,000 6,080,000 4,393,000 6,886,000 -4,682,000 969,000 4,252,000 398,000 -8,738,000 733,000 6,304,000 -1,180,000 536,000 1,766,000 126,000 135,000 33,000 
          operating lease liabilities
                            1,215,000 -5,414,000 -2,094,000 -3,511,000 10,917,000 7,129,000 1,689,000 -1,167,000 1,550,000            
          other long-term liabilities
                            -910,000 1,426,000 -26,778,000 1,207,000 -1,256,000 9,982,000 -1,521,000 -871,000 892,000 4,052,000 13,107,000 -1,130,000 933,000 31,215,000 -379,000 230,000 329,000 82,000   
          deconsolidation of a subsidiary
                                               
          payment for asset acquisition, net of cash acquired
                                                
          proceeds from public offering
                                                
          proceeds from public offering and hk ipo
                                                
          payment to acquire joint venture ("jv") minority interest
                                                
          proceeds from loans
                                                
          repayment of loans
                                                
          operating lease right-of-use assets
                              2,258,000 1,525,000 -8,990,000 -7,181,000 -699,000 -2,016,000 -1,588,000            
          proceeds from long-term loans
                                                
          repayment of long-term loans
                                                
          gain on deconsolidation of entity
                                                
          deconsolidation of entity
                                                
          proceeds from long-term bank loan
                                                
          proceeds from short-term bank loan
                               14,899,000 11,298,000                
          provision for doubtful accounts
                                2,022,000                
          unrealized gain on equity securities
                                -6,964,000                
          payment for the acquisition of land use right
                                               
          cash acquired in business combination, net of cash paid
                                               
          proceeds from sale or maturity of available-for-sale securities
                                       611,443,000 257,568,000 177,861,000 84,028,000 96,287,000 65,613,000    
          proceeds from public offering, net of underwriter discount
                                       758,001,000       
          payment of public offering cost
                                       -414,000       
          proceeds from public offering and hk ipo, net of underwriter discount
                                                
          payment of public offering and hk ipo costs
                                                
          proceeds from long-term bank loans
                                               
          repayment of long-term bank loans
                                                
          proceeds from short-term loan
                                         2,470,000    
          proceeds from shareholder loan
                                              
          realized gain on available-for-sale securities
                                                
          non-cash amortization of bond discount
                                  -51,000 -1,244,000 -2,408,000 -3,593,000           
          unbilled receivable
                                  6,114,000 2,498,000 -3,734,000 7,824,000 11,160,000 -7,555,000        
          prepayment of assets acquisition
                                                
          proceeds from follow-on public offering, net of underwriter discount
                                                
          payment of follow-on public offering cost
                                                
          proceeds from hk ipo and global follow-on public offering
                                                
          payment of hk ipo and global follow-on public offering costs
                                                
          repayment of long-term bank loan
                                                
          restricted cash, current
                                  -296,000 -333,000 14,900,000            
          restricted cash, non-current
                                  21,240,000 170,000 8,991,000            
          changes in operating assets and liabilities adjusted through accumulated deficit
                                      2,291,000        
          disposal gain on available-for-sale securities
                                   -996,000 -810,000            
          changes in fair value of financial instruments
                                             1,514,000 
          loss on disposal of property and equipment
                                     125,000      7,000    
          disposal loss on available-for-sale securities
                                             137,000 228,000 712,000 
          proceeds from disposal of property and equipment
                                                
          proceeds from exercise of warrants and rental deferral option
                                                
          proceeds from option exercises
                                     8,803,000 10,277,000 4,268,000 6,314,000 3,048,000       
          discount provided on sale of ordinary shares for business combination
                                               
          other non-cash income
                                       -1,854,000 -482,000        
          net cash from (provided by) investing activities
                                                
          restricted cash
                                       14,131,000 17,460,000        
          non-cash activities:
                                                
          cash, cash equivalents, and restricted cash at beginning of year
                                        239,602,000        
          cash, cash equivalents, and restricted cash at end of year
                                        508,094,000        
          other non-cash expenses
                                         -34,000       
          deferred rental
                                                
          proceeds from issuance of convertible preferred shares
                                                
          payment of convertible preferred shares issuance cost
                                                
          net increase in cash and cash equivalents
                                         31,092,000 -52,496,000 163,256,000 10,236,000 27,448,000 -150,422,000 190,637,000 
          cash and cash equivalents at beginning of period
                                         87,514,000 17,869,000 
          cash and cash equivalents at end of period
                                         31,092,000 -52,496,000 163,256,000 97,750,000 27,448,000 -150,422,000 208,506,000 
          conversion of senior promissory note
                                             14,693,000 
          conversion of deferred rental
                                             980,000 
          conversion of convertible preferred shares
                                             176,084,000 
          exercise of warrants and option
                                                
          follow-on public offering costs accrued in accounts payable
                                                
          operating activities
                                                
          advances from customers
                                                
          investing activities
                                                
          purchase of available-for-sale securities
                                          -436,419,000      
          investment in time deposits
                                                
          financing activities
                                                
          proceeds from exercise of warrants and options
                                            63,000    
          exercise of warrants and options
                                                
          initial public offering costs accrued in accrued expenses and other payables
                                               
          depreciation expense
                                           540,000 864,000    
          payment for the acquisition of land use rights
                                                
          proceeds from issuance of ordinary shares, net of underwriter discount
                                                
          payment of initial public offering cost
                                                
          proceeds from employee option exercises
                                                
          loss on sale of available-for-sale securities
                                                
          interest expense
                                             25,000 93,000 
          payment for land auction deposit
                                                
          net cash provided by investing activities
                                            43,543,000   40,343,000 
          net cash provided by financing activities
                                            2,533,000 7,640,000 4,521,000 170,049,000 
          depreciation expenses
                                             505,000 492,000 439,000 
          proceeds from disposal of available-for-sale securities
                                             67,761,000 46,900,000 43,646,000 
          proceeds from issuance of ordinary shares, net of initial public offering costs
                                             167,931,000 
          proceeds from issuance of preferred shares
                                                
          conversion of warrant and option liabilities
                                             3,687,000 
          proceeds from exercise of warrants
                                              2,118,000 
          initial public offering costs accrued for in accrued expenses and other payables
                                               166,000 
          gain on debt extinguishment
                                                
          acquisition of non-controlling interest
                                                
          proceeds from issuance of convertible promissory notes
                                                
          proceeds from issuance of secured guaranteed convertible promissory note
                                                
          proceeds from exercise of share options
                                                
          proceeds due to related parties
                                                
          repayment to related party
                                                
          net cash (used in) provided by financing activities
                                                
          repayment of subordinated convertible promissory note, convertible promissory notes and secured guaranteed convertible promissory note
                                                
          repayment of due to related parties