7Baggers

Beam Therapeutics Inc
(NASDAQ:BEAM) 

BEAM stock logo

Beam Therapeutics Inc., a biotechnology company, develops precision genetic medicines for patients suffering from serious diseases in the United States. The company is developing BEAM-101 for the treatment of sickle cell disease and beta thalassemia; BEAM-102 for the treatment of sickle cell disease...

Founded: 2017
Full Time Employees: 166
CEO: John Evans  
Sector: Healthcare
Industry: Biotechnology
Gene Editing
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At a glance:
Bull Thesis:
Bear Thesis:
Main Competitors:
Moat:
Income Statements:
Quarterly
Annual
    Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 
                              
      license and collaboration revenue
    		31,738,000 114,109,000 9,698,000 8,466,000 7,470,000 30,067,000 14,269,000 11,772,000 7,410,000 316,192,000 17,193,000 20,116,000 24,208,000 20,037,000 15,799,000 16,652,000 8,432,000 51,069,000 763,000        
      operating expenses:
    		                          
      research and development
    		104,524,000 99,275,000 109,769,000 101,758,000 98,816,000 101,444,000 94,258,000 87,041,000 84,818,000 140,077,000 100,050,000 97,608,000 99,646,000 86,341,000 85,287,000 74,556,000 65,410,000 96,781,000 54,623,000 45,577,000 190,106,000 32,451,000 29,825,000 19,354,000 21,549,000  
      general and administrative
    		34,429,000 32,279,000 26,740,000 26,859,000 27,940,000 28,660,000 26,515,000 29,626,000 26,724,000 43,257,000 25,410,000 24,656,000 23,490,000 22,681,000 21,815,000 24,062,000 19,247,000 17,772,000 15,774,000 13,403,000 10,273,000 8,354,000 7,502,000 6,937,000 6,812,000  
      total operating expenses
    		138,953,000 131,554,000 136,509,000 128,617,000 126,756,000 130,104,000 120,773,000 116,667,000 111,542,000 183,334,000 125,460,000 122,264,000 123,136,000 109,022,000 107,102,000 98,618,000 84,657,000 114,553,000 70,397,000 58,980,000 200,379,000 40,805,000 37,327,000 26,291,000 28,361,000  
      income from operations
    		-107,215,000 -17,445,000 -126,811,000 -120,151,000 -119,286,000 -100,037,000 -106,504,000 -104,895,000 -104,132,000 132,858,000 -108,267,000 -102,148,000 -98,928,000 -88,985,000 -91,303,000 -81,966,000 -76,225,000 -63,484,000 -69,634,000 -58,974,000 -200,373,000 -40,799,000 -37,321,000 -26,285,000 -28,355,000  
      yoy
    		-10.12% -82.56% 19.07% 14.54% 14.55% -175.30% -1.63% 2.69% 5.26% -249.30% 18.58% 24.62% 29.78% 40.17% 31.12% 38.99% -61.96% 55.60% 86.58% 124.36% 606.66%      
      qoq
    		514.59% -86.24% 5.54% 0.73% 19.24% -6.07% 1.53% 0.73% -178.38% -222.71% 5.99% 3.25% 11.17% -2.54% 11.39% 7.53% 20.07% -8.83% 18.08% -70.57% 391.12% 9.32% 41.99% -7.30%   
      other income:
    		                          
      change in fair value of derivative liabilities
    		2,500,000 50,000 -2,757,000 1,147,000 2,260,000 -128,000 -200,000 5,500,000 -2,900,000 -1,900,000 4,700,000 -900,000 5,600,000 3,000,000 -4,900,000 12,200,000 13,600,000 7,400,000 35,800,000 -42,300,000 -1,900,000 -54,700,000 2,700,000 -8,700,000 -2,700,000  
      change in fair value of non-controlling equity investments
    		16,000 -3,329,000 4,937,000 4,415,000 -2,081,000 -1,090,000 -2,064,000 -7,586,000 -3,353,000 -722,000 -11,221,000 6,148,000 -12,797,000 21,578,000 10,431,000 -4,124,000 -7,685,000          
      change in fair value of contingent consideration liabilities
    		514,000 -765,000 1,000,000 -28,000 -27,000 -27,000 -27,000 1,779,000 -133,000 1,863,000 6,002,000 2,171,000 -296,000 19,447,000 -875,000 -120,000 452,000 -4,407,000 10,599,000 -741,000 -305,000      
      interest and other income
    		9,867,000 10,640,000 10,903,000 12,326,000 9,864,000 10,928,000 12,127,000 14,190,000 11,849,000 12,064,000 12,698,000 11,953,000 9,961,000 7,611,000 4,982,000 2,060,000 644,000 54,000 9,000 -52,000 1,018,000 35,000 169,000 767,000 597,000  
      total other income
    		12,897,000 261,742,000 14,083,000 17,860,000 10,016,000 9,683,000 9,836,000 13,883,000 5,463,000 11,305,000 12,179,000 19,372,000 2,468,000 51,636,000 9,638,000 10,016,000 7,011,000 -1,223,000 41,516,000 -17,279,000 -1,187,000 -54,665,000 2,869,000    
      net income
    		-94,318,000 244,297,000 -112,728,000 -102,291,000 -109,270,000 -90,354,000 -96,668,000 -91,051,000 -98,669,000 142,797,000 -96,088,000 -82,776,000 -96,460,000 -38,349,000 -109,575,000 -71,950,000 -69,214,000 -64,707,000 -28,118,000 -76,253,000 -201,560,000 -95,464,000 -34,452,000 -34,218,000 -30,458,000  
      yoy
    		-13.68% -370.38% 16.61% 12.34% 10.74% -163.27% 0.60% 10.00% 2.29% -472.36% -12.31% 15.05% 39.36% -40.73% 289.70% -5.64% -65.66% -32.22% -18.38% 122.84% 561.76%      
      qoq
    		-138.61% -316.71% 10.20% -6.39% 20.94% -6.53% 6.17% -7.72% -169.10% -248.61% 16.08% -14.19% 151.53% -65.00% 52.29% 3.95% 6.97% 130.13% -63.13% -62.17% 111.14% 177.09% 0.68% 12.34%   
      unrealized gain on marketable securities
    		-2,181,000 321,000 780,000 -150,000 -519,000 -1,080,000 2,869,000 -189,000 -1,525,000 2,628,000 -9,000 -1,250,000 1,665,000 2,244,000 -484,000 -1,481,000 -2,659,000 -69,000 -12,000 55,000  -50,000 -132,000 517,000   
      comprehensive loss
    		-96,499,000 244,618,000 -111,948,000 -102,441,000 -109,789,000 -91,434,000 -93,799,000 -91,240,000 -100,194,000 145,425,000 -96,097,000 -84,026,000 -94,795,000 -36,105,000 -110,059,000 -73,431,000 -71,873,000 -64,776,000 -28,130,000 -76,198,000 -201,575,000 -95,514,000 -34,584,000 -33,701,000 -30,818,000  
      net loss per common share, basic and diluted
    		-910 2,510 -1,100 -1,000 -1,240 -1,090 -1,170 -1,110 -1,210 1,910 -1,220 -1,080 -1,330 -897.5 -1,560 -1,020 -1,010          
      weighted-average common shares outstanding, basic and diluted
    		103,262,001,000 98,905,577,000 102,570,801,000 101,995,184,000 87,975,311,000 82,313,008,000 82,410,095,000 82,312,467,000 81,698,633,000 77,151,771,000 79,024,647,000 76,335,175,000 72,273,829,000 70,015,305,000 70,343,196,000 70,210,227,000 68,703,864,000          
      net loss before income taxes
    		 244,297,000 -112,728,000 -102,291,000  -90,354,000 -96,668,000 -91,012,000  144,163,000 -96,088,000   -37,349,000 -81,665,000            
      provision for income taxes
    		       -39,000      -1,000,000 -2,410,000            
      loss from equity method investment
    		              -25,500,000            
      change in fair value of long-term investments
    		                 5,490,000 -4,892,000 25,814,000       
      reconciliation of net loss to net loss attributable to common stockholders:
    		                          
      accretion of redeemable convertible preferred stock to redemption value, including dividends on preferred stock
    		                        -1,277,000  
      net loss attributable to common stockholders
    		                 -64,707,000 -28,118,000 -76,253,000 -201,560,000 -95,464,000 -34,452,000 -34,218,000 -31,735,000  
      net loss per common share attributable to common stockholders, basic and diluted
    		                 -910 -420 -1,230 -3,350 -1,880 -690 -690 -1,030  
      weighted-average common shares used in net loss per share attributable to common stockholders, basic and diluted
    		                 64,227,676 66,377,611 62,210,239 60,210,120 46,733,221 50,087,747 49,430,138 30,725,077  
      license revenue
    		                   6,000 6,000 6,000 6,000 6,000 6,000  
      unrealized loss on marketable securities
    		                    -15,000    -360,000  
      total other expense
    		                       -7,933,000 -2,103,000  
    Balance Sheets:
    Quarterly
    Annual
      Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 
                                
        assets
      		                          
        current assets:
      		                          
        cash and cash equivalents
      		288,291,000 294,944,000 267,960,000 282,132,000 527,907,000 281,967,000 230,203,000 292,763,000 287,848,000 435,895,000 169,049,000 225,544,000 249,771,000 232,767,000 156,511,000 265,623,000 296,821,000 559,994,000 612,023,000 212,015,000 97,241,000 162,171,000 137,903,000 125,301,000 126,050,000 37,221,000 
        marketable securities
      		923,361,000 950,266,000 807,010,000 868,205,000 692,045,000 568,773,000 695,554,000 715,402,000 806,706,000 753,981,000 846,408,000 847,472,000 809,700,000 845,367,000 938,043,000 900,492,000 925,779,000 405,653,000 321,382,000 403,264,000 406,238,000 137,500,000 64,317,000 102,649,000 127,392,000 54,627,000 
        prepaid expenses and other current assets
      		55,301,000 23,478,000 23,577,000 25,127,000 27,662,000 27,409,000 19,777,000 21,275,000 27,156,000 21,167,000 24,084,000 21,789,000 23,560,000 14,762,000 14,358,000 13,775,000 16,884,000 7,360,000 8,019,000 12,714,000 11,101,000 8,650,000 6,487,000 6,879,000 6,192,000 2,696,000 
        total current assets
      		1,266,953,000 1,268,688,000 1,098,547,000 1,175,464,000 1,247,614,000 878,149,000 945,534,000 1,029,440,000 1,121,710,000 1,211,043,000 1,039,541,000 1,094,805,000 1,083,031,000 1,092,896,000 1,108,912,000 1,179,890,000 1,239,484,000 1,273,007,000 941,424,000 677,993,000 514,580,000 308,321,000 208,707,000 234,829,000 259,634,000 94,544,000 
        property and equipment
      		101,247,000 104,500,000 108,290,000 108,824,000 109,569,000 111,412,000 113,502,000 117,470,000 120,922,000 124,960,000 127,521,000 128,203,000 121,822,000 115,620,000 111,180,000 106,090,000 94,288,000 84,258,000 71,533,000 64,343,000 51,994,000 38,513,000 29,404,000 25,739,000 24,802,000 24,290,000 
        restricted cash
      		6,693,000 6,676,000 6,656,000 6,633,000 6,610,000 8,144,000 6,549,000 6,154,000 6,452,000 8,719,000 8,680,000 15,422,000 9,802,000 12,754,000 12,750,000 12,746,000 12,746,000 12,746,000 14,840,000 14,840,000 14,840,000 14,840,000 14,840,000 13,333,000 13,332,000 13,332,000 
        operating lease right-of-use assets
      		98,148,000 100,679,000 96,995,000 99,568,000 102,216,000 104,865,000 104,704,000 106,879,000 109,023,000 112,846,000 112,140,000 114,075,000 116,159,000 118,513,000 115,534,000 117,426,000 105,543,000 102,718,000 103,169,000 105,315,000 106,794,000 86,859,000 21,776,000 22,856,000 22,126,000 18,957,000 
        other assets
      		7,757,000 634,000 593,000 668,000 911,000 1,254,000 1,078,000 1,323,000 1,689,000 2,146,000 2,652,000 1,382,000 1,538,000 1,931,000 1,874,000 2,223,000 1,341,000 1,724,000 1,051,000 1,157,000 5,033,000 3,144,000 3,546,000 3,218,000 2,744,000 4,976,000 
        total assets
      		1,480,798,000 1,481,177,000 1,311,081,000 1,391,157,000 1,466,920,000 1,103,824,000 1,171,367,000 1,261,266,000 1,359,796,000 1,459,714,000 1,290,534,000 1,353,887,000 1,332,352,000 1,341,714,000 1,350,250,000 1,418,375,000 1,453,402,000 1,474,453,000 1,156,555,000 893,078,000 693,241,000 451,677,000 278,273,000 299,975,000 322,638,000 156,099,000 
        liabilities and stockholders’ equity
      		                          
        current liabilities:
      		                          
        accounts payable
      		12,286,000 10,231,000 9,545,000 10,556,000 7,699,000 3,871,000 3,812,000 4,429,000 2,790,000 1,617,000 3,177,000 6,886,000 14,063,000 9,029,000 7,024,000 7,095,000 6,266,000 7,474,000 7,282,000 8,030,000 7,983,000 6,314,000 6,569,000 6,154,000 6,101,000 7,846,000 
        accrued expenses and other current liabilities
      		39,291,000 55,267,000 42,314,000 40,904,000 30,233,000 47,468,000 51,769,000 67,138,000 86,437,000 111,664,000 41,769,000 37,519,000 37,847,000 48,059,000 38,600,000 35,069,000 24,062,000 28,921,000 22,965,000 19,581,000 14,976,000 18,487,000 18,309,000 7,202,000 8,480,000 7,852,000 
        current portion of derivative liabilities
      		5,200,000 7,700,000 6,500,000 3,900,000 5,200,000 8,400,000 8,400,000                    
        current portion of deferred revenue
      		304,000 6,659,000 110,320,000 105,822,000 85,204,000 108,858,000 89,327,000 84,925,000 72,111,000 68,706,000 153,484,000 139,127,000 142,737,000 135,974,000 159,902,000 139,666,000 115,049,000 86,270,000 12,822,000 10,024,000       
        current portion of lease liability
      		14,781,000 14,364,000 12,688,000 12,949,000 13,210,000 13,469,000 12,936,000 12,641,000 12,181,000 12,778,000 11,951,000 11,492,000 11,157,000 10,380,000 9,823,000 9,512,000 9,359,000 7,540,000 6,484,000 3,491,000 3,885,000 4,218,000 4,340,000 4,698,000 4,699,000 4,337,000 
        current portion of contingent consideration liabilities
      		2,703,000 2,714,000                         
        total current liabilities
      		74,565,000 96,935,000 182,559,000 174,131,000 141,546,000 182,066,000 166,244,000 177,333,000 187,219,000 205,565,000 220,365,000 209,536,000 219,925,000 223,595,000 238,859,000 212,278,000 218,798,000 213,435,000 101,391,000 128,715,000 102,086,000 102,337,000 47,451,000 38,950,000 31,440,000 29,138,000 
        long-term lease liability
      		135,848,000 139,759,000 138,732,000 141,854,000 144,919,000 147,956,000 149,129,000 152,596,000 155,939,000 159,911,000 160,637,000 163,851,000 165,298,000 168,625,000 165,075,000 163,985,000 136,034,000 134,810,000 133,120,000 132,793,000 125,825,000 96,014,000 23,810,000 24,901,000 24,059,000 21,187,000 
        long-term portion of contingent consideration liabilities
      		5,449,000 5,952,000 6,708,000                        
        long-term portion of debt
      		100,193,000                          
        other liabilities
      		305,000 173,000 266,000 357,000 414,000 504,000 481,000 679,000 719,000 298,000 1,048,000 1,192,000 173,000 224,000 253,000 305,000 11,090,000 2,793,000 852,000 903,000 1,342,000 2,471,000 2,493,000 406,000 412,000 418,000 
        total liabilities
      		316,360,000 242,819,000 345,079,000 344,344,000 343,784,000 370,279,000 380,050,000 407,172,000 446,306,000 478,385,000 511,593,000 542,244,000 570,846,000 608,240,000 635,773,000 618,214,000 624,334,000 647,715,000 302,741,000 344,527,000 270,812,000 206,116,000 78,202,000 69,153,000 61,244,000 55,154,000 
        commitments and contingencies
      		                          
        stockholders’ equity:
      		                          
        preferred stock, 0.01 par value...
      		                          
        common stock, 0.01 par value...
      		1,027,000 1,017,000 1,014,000 1,008,000 1,006,000 836,000 826,000 824,000 823,000 816,000 794,000 780,000 744,000 712,000 705,000 703,000 698,000 684,000 677,000 645,000 617,000 573,000 504,000 496,000 491,000 73,000 
        additional paid-in capital
      		2,900,018,000 2,877,449,000 2,855,118,000 2,823,987,000 2,797,871,000 2,298,661,000 2,265,009,000 2,233,989,000 2,202,146,000 2,169,798,000 2,112,857,000 2,049,476,000 1,915,349,000 1,792,554,000 1,737,459,000 1,713,086,000 1,668,567,000 1,594,378,000 1,556,685,000 1,223,324,000 1,021,032,000 642,633,000 501,698,000 497,873,000 494,749,000 1,851,000 
        accumulated other comprehensive income
      		-1,070,000 1,111,000 790,000 10,000 160,000 679,000 1,759,000 -1,110,000 -921,000 604,000 -2,024,000 -2,015,000 -765,000 -2,430,000 -4,674,000 -4,190,000 -2,709,000 -50,000 19,000 31,000  -9,000 41,000 173,000 -344,000 16,000 
        accumulated deficit
      		-1,735,537,000 -1,641,219,000 -1,890,920,000 -1,778,192,000 -1,675,901,000 -1,566,631,000 -1,476,277,000 -1,379,609,000 -1,288,558,000 -1,189,889,000 -1,332,686,000 -1,236,598,000 -1,153,822,000 -1,057,362,000 -1,019,013,000 -909,438,000 -837,488,000 -768,274,000 -703,567,000 -675,449,000 -599,196,000 -397,636,000 -302,172,000 -267,720,000 -233,502,000 -203,044,000 
        total stockholders’ equity
      		1,164,438,000 1,238,358,000 966,002,000 1,046,813,000 1,123,136,000 733,545,000 791,317,000 854,094,000 913,490,000 981,329,000 778,941,000 811,643,000 761,506,000 733,474,000 714,477,000 800,161,000 829,068,000 826,738,000 853,814,000 548,551,000 422,429,000 245,561,000 200,071,000 230,822,000 261,394,000  
        total liabilities and stockholders’ equity
      		1,480,798,000 1,481,177,000 1,311,081,000 1,391,157,000 1,466,920,000 1,103,824,000 1,171,367,000 1,261,266,000 1,359,796,000 1,459,714,000 1,290,534,000 1,353,887,000 1,332,352,000 1,341,714,000 1,350,250,000 1,418,375,000 1,453,402,000  1,156,555,000 893,078,000       
        long-term portion of deferred revenue
      		  10,160,000 20,319,000 49,403,000 33,218,000 57,816,000 75,487,000 99,573,000 109,888,000 124,653,000 156,202,000 171,708,000 202,179,000 198,288,000 208,824,000 225,093,000 262,303,000 36,820,000 40,381,000       
        long-term portion of derivative liabilities
      		  6,654,000 6,497,000 6,344,000 5,404,000 5,276,000                    
        current portion of consideration liabilities
      		  1,192,000                        
        contingent consideration liabilities
      		   1,186,000 1,158,000 1,131,000 1,104,000 1,077,000 2,856,000 2,723,000 4,586,000 10,588,000 12,759,000 12,463,000 31,910,000 31,035,000 30,915,000 31,367,000 26,960,000 37,559,000 36,818,000      
        derivative liabilities
      		       8,200,000 13,700,000 10,800,000 8,900,000 13,600,000 12,700,000 18,300,000 21,300,000 16,400,000 28,600,000 42,200,000 49,600,000 85,400,000 73,100,000 71,200,000 16,500,000 19,200,000 10,500,000 7,800,000 
        current portion of equipment financing liability
      		          1,084,000 912,000 1,421,000 1,853,000 2,210,000 2,389,000 2,337,000 2,287,000 2,238,000 2,189,000 2,142,000 2,118,000 1,733,000 1,696,000 1,660,000 1,303,000 
        long-term equipment financing liability
      		          304,000 875,000 983,000 1,154,000 1,388,000 1,787,000 2,404,000 3,007,000 3,598,000 4,176,000 4,741,000 5,294,000 4,448,000 4,896,000 5,333,000 4,411,000 
        collaboration receivable
      		                 300,000,000  50,000,000       
        accrued sub-license fees
      		               2,147,000 33,125,000 38,743,000         
        total liabilities, redeemable convertible preferred stock, and stockholders’ equity
      		                 1,474,453,000   693,241,000 451,677,000 278,273,000 299,975,000 322,638,000  
        long-term investments
      		                  24,538,000 29,430,000       
        accumulated other comprehensive loss
      		                    -24,000      
        liabilities, redeemable convertible preferred stock, and stockholders’ equity
      		                          
        redeemable convertible preferred stock
      		                         302,049,000 
        stockholders’ equity
      		                          
        liabilities, redeemable convertible preferred stock, and stockholders’ deficit
      		                          
        financing milestone liabilities payable
      		                          
        deferred rent, current portion
      		                          
        deferred rent, net of current portion
      		                          
        stockholders’ deficit:
      		                          
        total stockholders’ deficit
      		                         -201,104,000 
        total liabilities, redeemable convertible preferred stock, and stockholders’ deficit
      		                         156,099,000 
      Cashflow Statements:
      Quarterly
      Annual
        Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 
                                 
          operating activities
        		                         
          net loss
        		-94,318,000 244,297,000 -112,728,000 -102,291,000 -109,270,000 -90,354,000 -96,668,000 -91,051,000 -98,669,000 142,797,000 -96,088,000 -82,776,000 -96,460,000       -76,253,000 -201,560,000 -95,464,000 -34,452,000 -34,218,000 -30,458,000 
          adjustments to reconcile net loss to net cash from operating activities:
        		                         
          depreciation and amortization
        		5,605,000 5,668,000 5,560,000 5,538,000 5,528,000 5,443,000 5,475,000 5,576,000 5,431,000 5,362,000 5,187,000 4,816,000 4,647,000 3,944,000 3,473,000 3,418,000 3,312,000 2,634,000 1,750,000 1,669,000 1,398,000     
          amortization of investment discount
        		-2,763,000 -3,258,000 -4,233,000 -4,618,000 -3,849,000 -4,640,000 -5,623,000 -5,926,000 -6,576,000  -7,884,000 -7,573,000 -6,932,000 -5,102,000 -3,217,000 -701,000 -390,000 -47,000 -25,000 -18,000 15,000 69,000    
          amortization of debt discount
        		35,000                         
          stock-based compensation expense
        		19,044,000 20,448,000 22,747,000 24,367,000 26,682,000 30,218,000 29,559,000 31,604,000 29,281,000 22,617,000 25,835,000 26,278,000 23,917,000 22,499,000 22,209,000 21,578,000 18,035,000 15,502,000 12,968,000 10,452,000 4,648,000 6,807,000 3,012,000 2,769,000 2,792,000 
          change in operating lease right-of-use assets
        		2,532,000 2,518,000 2,573,000 2,648,000 2,649,000  2,438,000 2,394,000 2,361,000 2,402,000 2,288,000 2,475,000 2,354,000 2,193,000 2,143,000 2,097,000 1,997,000 2,209,000 2,147,000 2,275,000 2,359,000 1,672,000 1,080,000 1,033,000 952,000 
          change in fair value of derivative liabilities
        		-2,500,000 -50,000 2,757,000 -1,147,000 -2,260,000 128,000 200,000 -5,500,000 2,900,000 1,900,000 -4,700,000 900,000 -5,600,000 -3,000,000 4,900,000 -12,200,000 -13,600,000 -7,400,000 -35,800,000 42,300,000 1,900,000 54,700,000 -2,700,000 8,700,000 2,700,000 
          change in fair value of contingent consideration liabilities
        		-514,000 765,000 -1,000,000 28,000 27,000 27,000 27,000 -1,779,000 133,000 -1,863,000 -6,002,000 -2,171,000 296,000 -19,447,000 875,000 120,000 -452,000 4,407,000 -10,599,000 741,000 305,000     
          change in fair value of non-controlling equity investments
        		-16,000 3,329,000 -4,937,000 -4,415,000 2,081,000 1,090,000 2,064,000 7,586,000 3,353,000 722,000 11,221,000 -6,148,000 12,797,000 -21,578,000 -10,431,000 4,124,000 7,685,000 4,270,000 4,892,000       
          changes in operating assets and liabilities:
        		                         
          prepaid expenses and other current assets
        		-31,861,000 59,000 1,625,000 2,778,000 49,000 -7,807,000 1,744,000 6,246,000 -5,532,000 3,570,000 -3,567,000 1,929,000 -8,405,000 -561,000 -235,000 2,228,000 -9,185,000 13,000 3,839,000 -741,000 -2,365,000 -2,059,000 548,000 -656,000 -3,559,000 
          accounts payable
        		2,216,000 1,194,000 -1,589,000 2,642,000 3,793,000 -550,000 -700,000 1,772,000 1,285,000 -1,768,000 -3,045,000 -2,534,000 -231,000 2,900,000 623,000 102,000 -1,252,000 2,159,000 -1,723,000 1,048,000 -666,000 194,000 -81,000 418,000 -471,000 
          accrued expenses and other liabilities
        		-16,258,000 14,298,000 1,977,000 9,868,000 -18,458,000 -4,075,000 -9,849,000 -19,486,000 -24,275,000 70,401,000 7,416,000 -266,000 -9,888,000 8,443,000 3,938,000 -12,781,000 -16,533,000 41,096,000 1,171,000 6,105,000 -4,458,000 2,816,000 4,458,000 -617,000 378,000 
          operating lease liabilities
        		-3,494,000 -3,500,000 -3,383,000 -3,325,000 -3,297,000 -3,275,000 -3,435,000 -3,133,000 -3,108,000 -3,007,000 -3,107,000 -1,504,000 -2,550,000 -1,066,000 1,151,000 14,125,000 -1,780,000 820,000 3,320,000 5,777,000 6,111,000 6,400,000 -1,448,000 -922,000 -879,000 
          deferred revenue
        		-6,355,000 -113,820,000 -5,661,000 -8,466,000 -7,470,000 -5,067,000 -13,269,000 -11,272,000 -6,910,000 -99,543,000 -17,192,000 -19,116,000 -23,708,000 -20,037,000 -15,799,000 8,348,000 -8,432,000 298,932,000 -764,000       
          other long-term liabilities
        		134,000 -91,000 -93,000 -57,000 -89,000 22,000 -88,000 -40,000 579,000 -1,017,000 -146,000 1,021,000 -52,000 -30,000 -51,000 -10,784,000 8,296,000 1,942,000 -51,000 -45,000 -57,000 -1,094,000 2,087,000 -6,000 -6,000 
          net cash from operating activities
        		-128,513,000 -83,289,000 -81,479,000 -76,450,000 -103,884,000 -76,365,000 -88,125,000 -83,009,000 -99,747,000 135,073,000 -89,784,000 -84,669,000 -109,815,000 -69,191,000 -74,496,000 -52,276,000 218,490,000 1,830,000 3,007,000 -32,527,000 -38,578,000 -24,298,000 -21,213,000 -22,837,000 -27,393,000 
          capital expenditures
        		-2,232,000 -3,734,000 -5,011,000 -3,136,000 -3,065,000 -2,970,000 -1,577,000 -1,961,000 -2,438,000 -3,589,000 -7,948,000 -16,178,000 -6,017,000 -8,261,000 -11,787,000 -21,644,000 -7,259,000 -13,369,000 -5,780,000 -16,184,000 -11,478,000 -8,125,000 -2,819,000 -2,367,000 -3,046,000 
          free cash flows
        		-130,745,000 -87,023,000 -86,490,000 -79,586,000 -106,949,000 -79,335,000 -89,702,000 -84,970,000 -102,185,000 131,484,000 -97,732,000 -100,847,000 -115,832,000 -77,452,000 -86,283,000 -73,920,000 211,231,000 -11,539,000 -2,773,000 -48,711,000 -50,056,000 -32,423,000 -24,032,000 -25,204,000 -30,439,000 
          investing activities
        		                         
          purchases of property and equipment
        		-2,232,000 -3,734,000 -5,011,000 -3,136,000 -3,065,000 -2,970,000 -1,577,000 -1,961,000 -2,438,000 -3,589,000 -7,948,000 -16,178,000 -6,017,000 -8,261,000 -11,787,000 -21,644,000 -7,259,000 -13,369,000 -5,780,000 -16,184,000 -11,478,000 -8,125,000 -2,819,000 -2,367,000 -3,046,000 
          purchases of marketable securities
        		-153,792,000 -361,038,000 -175,643,000 -333,942,000 -339,169,000 0 -156,725,000 -134,473,000 -195,241,000 -53,272,000 -273,707,000 -390,827,000 -266,532,000 -238,390,000 -358,031,000 -330,188,000 -690,390,000 -170,477,000 -178,500,000 -139,028,000 -289,218,000 -114,518,000 -31,135,000 -18,240,000 -117,719,000 
          maturities of marketable securities
        		181,293,000 218,033,000 240,644,000 166,667,000 217,145,000 129,250,000 183,000,000 223,927,000 144,215,000 154,960,000 271,425,000 365,525,000 298,000,000 360,090,000 333,644,000 350,570,000 160,310,000 106,350,000 260,395,000 142,075,000 20,450,000 41,216,000 69,182,000 43,475,000 44,723,000 
          net cash from investing activities
        		25,269,000 108,407,000 65,655,000 -170,411,000 -125,089,000 126,280,000 24,698,000 87,493,000 -53,464,000 98,099,000 -10,230,000 -41,480,000 25,451,000 113,439,000 -36,174,000 -1,262,000 -537,339,000 -77,496,000 76,115,000 -13,137,000 -279,626,000 -81,427,000 35,228,000 22,868,000 -76,792,000 
          financing activities
        		                         
          proceeds from issuance of common shares and pre-funded warrants, net of issuance costs
        		 0 0 -646,000 471,159,000                     
          proceeds from issuances of stock under espp
        		1,510,000 0 1,263,000 0 1,501,000 -1,000 1,224,000 0 1,398,000 0 1,324,000 0 1,708,000 -1,000 1,664,000 0 1,412,000         
          proceeds from exercise of stock options
        		2,025,000 1,886,000 412,000 1,755,000 719,000 3,445,000 239,000 240,000 1,676,000 745,000 1,292,000 702,000 3,392,000 764,000 502,000 646,000 820,000 1,969,000 2,702,000 3,197,000 1,758,000 2,086,000 557,000 360,000 152,000 
          proceeds from the issuance of debt, net of fees paid to lender
        		93,886,000                         
          payments of debt issuance costs
        		-813,000                         
          net cash from financing activities
        		96,608,000 1,886,000 1,675,000 1,109,000 473,379,000 3,444,000 1,262,000 133,000 2,897,000 33,713,000 36,777,000 107,542,000 98,416,000 32,012,000 1,562,000 22,340,000 55,676,000 21,543,000 320,886,000 160,438,000 253,274,000 129,993,000 94,000 -779,000 193,014,000 
          net change in cash, cash equivalents and restricted cash
        		-6,636,000 27,004,000 -14,149,000 -245,752,000 244,406,000 53,359,000 -62,165,000 4,617,000 -150,314,000 266,885,000 -63,237,000 -18,607,000 14,052,000 76,260,000 -109,108,000 -31,198,000 -263,173,000  400,008,000 114,774,000 -64,930,000  14,109,000 -748,000 88,829,000 
          cash, cash equivalents and restricted cash—beginning of period
        		301,620,000  0 0 290,111,000 0 0 0 444,614,000 0 0 0 245,521,000 0 0 0 572,740,000 0 0 0 177,011,000 0 0 0 50,553,000 
          cash, cash equivalents and restricted cash—end of period
        		294,984,000  -14,149,000 -245,752,000 534,517,000 53,359,000 -62,165,000 4,617,000 294,300,000 266,885,000 -63,237,000 -18,607,000 259,573,000 76,260,000 -109,108,000 -31,198,000 309,567,000 -54,123,000 400,008,000 114,774,000 112,081,000 24,268,000 14,109,000 -748,000 139,382,000 
          in-process research and development charge
        		 0                0 0 0 154,953,000     
          realized loss on sale of marketable securities
        		 0                        
          gain on sale of equity method investment
        		                         
          proceeds from sale of marketable securities
        		 0                        
          cash paid for acquisition
        		 0                        
          proceeds from sale of equity method investment
        		                         
          equipment financings
        		                         
          proceeds from private stock issuance
        		                         
          cash, cash equivalents and restricted cash—beginning of year
        		                         
          cash, cash equivalents and restricted cash—end of year
        		                         
          repayment of equipment financings
        		      -201,000 -107,000 -177,000  -400,000 -617,000 -603,000 -590,000 -579,000 -565,000 -553,000 -542,000 -530,000 -517,000 -529,000 -411,000 -411,000 -432,000 -315,000 
          loss from equity method investment
        		                         
          amortization of operating lease right-of-use assets
        		                         
          other
        		             0 0 0 3,000 0 0 1,039,000 -976,000 0 0   
          collaboration receivable
        		             0 0 0 300,000,000         
          proceeds from issuance of common shares, net of commissions
        		         0 34,945,000 107,642,000 93,981,000 31,893,000 0 22,362,000 54,003,000 20,244,000 318,923,000       
          payment of equity offering costs
        		         0 -384,000 -185,000 -62,000 -54,000 -25,000 -103,000 -6,000  -209,000 -524,000 -7,955,000     
          amortization of investment (discount) premiums
        		                         
          other long-term assets
        		                 0 0 -12,000 -185,000 -98,000 12,000 9,000 -77,000 
          net cash acquired from guide
        		                 0 0 0 620,000     
          non-cash research and development license expense
        		                     487,000 4,900,000 0 264,000 
          purchase of non-controlling equity investment
        		                         
          proceeds from initial public offering, net of underwriting discount
        		                     0 0 0 192,510,000 
          proceeds from october 2020 public offering, net of underwriting discount
        		                         
          proceeds from equipment financings
        		                     1,642,000 0 0 1,625,000 
          net income
        		              -109,575,000 -71,950,000 -69,214,000 -64,707,000        
          adjustments to reconcile net income to net cash from operating activities:
        		                         
          income from equity method investment
        		                         
          financing milestone liabilities
        		                         
          proceeds from issuance of series b preferred stock
        		                         
          payment of initial and follow-on equity offering costs
        		                         
          net increase in cash, cash equivalents and restricted cash
        		                         
          purchase of long-term investment
        		                     0 0 0 -750,000 
          proceeds from offering of common stock
        		                    260,000,000     
          depreciation
        		                     1,272,000 1,218,000 1,145,000 1,100,000 
          payment of initial and follow-on public offering costs
        		                     -342,000    
          net increase in in cash, cash equivalents and restricted cash
        		                         
          amortization of investment premiums
        		                       25,000 -129,000 
          payment of initial public offering costs
        		                       -707,000 -958,000 
          supplemental disclosure of cash flow information:
        		                         
          cash paid for interest
        		                       148,000 134,000 
          supplemental disclosure of noncash investing and financing activities:
        		                         
          conversion of redeemable convertible preferred stock to common stock upon closing of the initial public offering
        		                       0 303,326,000 
          property and equipment additions in accounts payable and accrued expenses
        		                       -285,000 1,032,000 
          operating lease liabilities arising from obtaining right-of-use assets
        		                       1,763,000 4,032,000 
          receipt of common stock in exchange for technology license
        		                         
          issuance of common stock for research and development license
        		                         
          equity issuance costs in accounts payable and accrued expenses
        		                        707,000 
          accretion of redeemable convertible preferred stock to redemption value, including dividends on preferred stock
        		                       0 1,277,000 
          loss on issuance of preferred stock in connection with blink merger
        		                         
          loss on issuance of preferred stock to investors
        		                         
          change in fair value of preferred stock tranche liabilities
        		                         
          deferred rent liabilities
        		                         
          proceeds from issuance of series a-1 preferred stock
        		                         
          proceeds from issuance of series a-2 preferred stock
        		                         
          proceeds from issuance of blink series a preferred stock
        		                         
          equity issuance costs
        		                         
          issuance of common stock in connection with blink merger
        		                         
          issuance of common stock to founders in connection with blink merger
        		                         
          issuance of series a-2 preferred stock in connection with blink merger
        		                         
          issuance of series a-1 and a-2 preferred stock for research and development license
        		                         
          recognition and derecognition of preferred stock tranche liabilities