Quarterly
Annual
| Unit: USD | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 | 2021-03-31 | 2020-12-31 | 2020-09-30 | 2019-12-31 | 2019-09-30 | 2019-06-30 | 2019-03-31 | 2018-12-31 | 2018-09-30 | 2018-06-30 | 2018-03-31 | 2017-12-31 | 2017-09-30 | 2017-06-30 | 2017-03-31 | 2016-12-31 | 2016-09-30 | 2016-06-30 | 2016-03-31 | 2015-12-31 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
revenues: | ||||||||||||||||||||||||||||||||||||||
product sales | 169,784,000 | 148,959,000 | 120,358,000 | 117,325,000 | 103,736,000 | 86,520,000 | 74,096,000 | 70,747,000 | 57,127,000 | 46,017,000 | 28,569,000 | 24,371,528 | 16,845,792 | 8,819,786 | ||||||||||||||||||||||||
royalty revenue | 1,208,000 | 1,083,000 | 1,105,000 | 643,750 | 1,026,000 | 646,000 | 903,000 | 783,000 | 667,000 | 683,000 | 272,000 | |||||||||||||||||||||||||||
total revenues | 170,992,000 | 150,042,000 | 121,463,000 | 118,766,000 | 104,762,000 | 87,166,000 | 74,999,000 | 71,530,000 | 57,794,000 | 46,700,000 | 94,576,000 | |||||||||||||||||||||||||||
yoy | 63.22% | 72.13% | 61.95% | 66.04% | 81.27% | 86.65% | -20.70% | |||||||||||||||||||||||||||||||
qoq | 13.96% | 23.53% | 2.27% | 13.37% | 20.19% | 16.22% | 4.85% | 23.77% | 23.76% | -50.62% | ||||||||||||||||||||||||||||
operating expenses: | ||||||||||||||||||||||||||||||||||||||
cost of revenue | 11,912,000 | 13,448,000 | 9,789,000 | 10,514,000 | 8,437,000 | 8,055,000 | 6,297,000 | 7,378,000 | 6,532,000 | 4,599,000 | 7,556,000 | |||||||||||||||||||||||||||
gross profit | 159,080,000 | 136,594,000 | 111,674,000 | 108,252,000 | 96,325,000 | 79,111,000 | 68,702,000 | 64,152,000 | 51,262,000 | 42,101,000 | 87,020,000 | |||||||||||||||||||||||||||
yoy | 65.15% | 72.66% | 62.55% | 68.74% | 87.91% | 87.91% | -21.05% | |||||||||||||||||||||||||||||||
qoq | 16.46% | 22.31% | 3.16% | 12.38% | 21.76% | 15.15% | 7.09% | 25.15% | 21.76% | -51.62% | ||||||||||||||||||||||||||||
gross margin % | 93.03% | 91.04% | 91.94% | 91.15% | 91.95% | 90.76% | 91.60% | 89.69% | 88.70% | 90.15% | 92.01% | |||||||||||||||||||||||||||
research and development | 40,162,000 | 49,541,000 | 44,785,000 | 55,006,000 | 45,388,000 | 49,853,000 | 36,830,000 | 30,803,000 | 28,767,000 | 20,581,000 | 17,793,000 | 14,693,083 | 14,877,021 | 15,792,202 | 12,585,141 | 13,781,453 | 13,180,258 | 14,503,326 | 16,595,689 | 17,384,729 | 14,795,493 | 19,205,271 | 15,835,573 | 11,003,142 | 7,603,081 | 7,151,232 | 6,040,780 | 5,550,532 | 4,752,511 | 4,493,910 | 4,471,126 | 5,007,361 | 5,985,219 | 5,806,771 | 5,568,777 | 5,298,060 | 4,526,252 | |
selling, general and administrative | 150,235,000 | 130,280,000 | 120,787,000 | 113,271,000 | 95,564,000 | 103,554,000 | 98,970,000 | 86,809,000 | 83,188,000 | 78,935,000 | 74,191,000 | 61,497,347 | 40,892,443 | 31,160,140 | ||||||||||||||||||||||||
loss in fair value of contingent consideration | 13,185,000 | 2,160,000 | ||||||||||||||||||||||||||||||||||||
intangible asset amortization | 1,607,000 | 1,589,000 | 1,572,000 | 1,607,000 | 1,606,000 | 1,590,000 | 1,589,000 | 1,607,000 | 1,607,000 | 1,589,000 | 1,572,000 | 1,606,789 | 1,606,789 | 925,650 | ||||||||||||||||||||||||
total operating expenses | 217,101,000 | 186,756,000 | 178,445,000 | 191,383,000 | 167,386,000 | 165,212,000 | 142,274,000 | 169,804,000 | 119,914,000 | 111,757,000 | 100,950,000 | 84,288,497 | 59,257,964 | 48,000,828 | 38,288,872 | 32,608,040 | 33,407,142 | 30,847,687 | 27,844,061 | 27,744,236 | 21,126,801 | 24,428,170 | 18,947,235 | 13,448,219 | 10,421,473 | 9,450,315 | 8,243,459 | 7,989,593 | 7,163,210 | 6,444,120 | 6,297,416 | 6,750,738 | 7,672,033 | 7,625,560 | 7,207,803 | 6,827,280 | 5,882,865 | |
income from operations | -46,109,000 | -36,714,000 | -56,982,000 | -72,617,000 | -62,624,000 | -78,046,000 | -67,275,000 | -98,274,000 | -62,120,000 | -65,057,000 | -6,374,000 | -59,916,969 | -42,412,172 | -39,181,042 | -38,288,872 | -32,608,040 | -33,407,142 | -30,847,687 | -27,844,061 | -27,744,236 | -21,126,801 | -24,428,170 | -18,947,235 | -13,448,219 | -10,421,473 | -9,450,315 | -8,243,459 | -7,989,593 | -7,163,210 | -6,444,120 | -6,297,416 | -6,750,738 | -7,672,033 | -7,625,560 | -7,207,803 | -6,827,280 | -5,882,865 | |
yoy | -26.37% | -52.96% | -15.30% | -26.11% | 0.81% | 19.97% | 955.46% | 64.02% | 46.47% | 66.04% | -83.35% | 83.75% | 26.96% | 27.01% | 37.51% | 17.53% | 58.13% | 26.28% | 46.96% | 106.30% | 102.72% | 158.49% | 129.85% | 68.32% | 45.49% | 46.65% | 30.90% | 18.35% | -6.63% | -15.49% | -12.63% | -1.12% | 30.41% | |||||
qoq | 25.59% | -35.57% | -21.53% | 15.96% | -19.76% | 16.01% | -31.54% | 58.20% | -4.51% | 920.66% | -89.36% | 41.27% | 8.25% | 2.33% | 17.42% | -2.39% | 8.30% | 10.79% | 0.36% | 31.32% | -13.51% | 28.93% | 40.89% | 29.04% | 10.28% | 14.64% | 3.18% | 11.54% | 11.16% | 2.33% | -6.72% | -12.01% | 0.61% | 5.80% | 5.57% | 16.05% | ||
operating margin % | -26.97% | -24.47% | -46.91% | -61.14% | -59.78% | -89.54% | -89.70% | -137.39% | -107.49% | -139.31% | -6.74% | |||||||||||||||||||||||||||
interest expense | -1,120,000 | -1,834,000 | -2,431,000 | -2,210,000 | -1,978,000 | -1,299,000 | -1,082,000 | -702,000 | -757,000 | -2,730,000 | -2,264,000 | -1,322,643 | -2,411,040 | |||||||||||||||||||||||||
loss on debt extinguishment | -10,385,000 | |||||||||||||||||||||||||||||||||||||
income before income taxes | -47,229,000 | -48,933,000 | -59,413,000 | -74,827,000 | -64,602,000 | -79,345,000 | -68,357,000 | -98,976,000 | -62,877,000 | -67,787,000 | ||||||||||||||||||||||||||||
income tax benefit | 960,000 | -321,250 | 678,000 | 617,000 | ||||||||||||||||||||||||||||||||||
net income | -47,229,000 | -47,973,000 | -59,413,000 | -74,912,000 | -64,602,000 | -79,345,000 | -68,357,000 | -98,651,000 | -62,199,000 | -67,170,000 | -11,218,000 | -61,239,612 | -44,823,212 | -41,438,516 | -39,632,311 | -33,976,136 | -34,882,677 | -32,284,209 | -29,259,970 | -29,164,647 | -22,924,815 | -24,806,984 | -19,135,612 | -13,762,214 | -10,640,376 | -9,597,015 | -8,281,974 | -8,280,916 | -4,805,559 | -7,430,501 | -6,433,536 | -7,084,316 | -7,995,039 | -7,328,938 | -7,194,584 | -6,812,190 | -5,865,941 | |
yoy | -26.89% | -39.54% | -13.08% | -24.06% | 3.86% | 18.13% | 509.35% | 61.09% | 38.77% | 62.10% | -71.69% | 80.24% | 28.50% | 28.36% | 35.45% | 16.50% | 52.16% | 30.14% | 52.91% | 111.92% | 115.45% | 158.49% | 131.05% | 66.19% | 121.42% | 29.16% | 28.73% | 16.89% | -39.89% | 1.39% | -10.58% | 3.99% | 36.30% | |||||
qoq | -1.55% | -19.26% | -20.69% | 15.96% | -18.58% | 16.07% | -30.71% | 58.61% | -7.40% | 498.77% | -81.68% | 36.62% | 8.17% | 4.56% | 16.65% | -2.60% | 8.05% | 10.34% | 0.33% | 27.22% | -7.59% | 29.64% | 39.04% | 29.34% | 10.87% | 15.88% | 0.01% | 72.32% | -35.33% | 15.50% | -9.19% | -11.39% | 9.09% | 1.87% | 5.61% | 16.13% | ||
net income margin % | -27.62% | -31.97% | -48.91% | -63.08% | -61.67% | -91.03% | -91.14% | -137.92% | -107.62% | -143.83% | -11.86% | |||||||||||||||||||||||||||
net income per common share, basic and diluted | -940 | -970 | -1,220 | -1,540 | -1,340 | -1,670 | -1,440 | -2,130 | -1,320 | -1,540 | -260 | -1.43 | -1.07 | -1.06 | -1.03 | -0.9 | -0.93 | -0.86 | -0.78 | -0.79 | -0.61 | -0.72 | -0.56 | -0.41 | -0.32 | -0.32 | -0.31 | -0.32 | -0.19 | -0.243 | -0.27 | -0.3 | -0.41 | -0.26 | -0.38 | -0.36 | -0.31 | |
weighted-average common shares outstanding, basic and diluted | 50,021,851,000 | 49,442,001,000 | 48,871,163,000 | 47,914,253,000 | 48,140,519,000 | 47,573,229,000 | 47,393,563,000 | 45,425,212,000 | 47,117,196,000 | 43,669,820,000 | 43,523,631,000 | 40,655,941 | 41,704,362 | 39,081,100 | 38,323,167 | 37,618,599 | 37,680,966 | 37,595,069 | 37,429,450 | 37,206,928 | 37,311,726 | 34,020,257 | 34,445,489 | 33,801,749 | 33,052,468 | 26,883,656 | 26,325,904 | 25,791,177 | 25,501,188 | 23,634,040 | 23,595,702 | 19,537,897 | 19,149,906 | 19,149,417 | 19,149,417 | |||
gain in fair value of contingent consideration | -8,102,000 | 1,512,000 | 4,284,750 | 16,391,000 | -1,412,000 | 1,427,750 | -180,000 | 6,053,000 | -162,000 | -225,530 | -42,120 | -860,000 | ||||||||||||||||||||||||||
income tax expense | ||||||||||||||||||||||||||||||||||||||
license revenue | 65,735,000 | |||||||||||||||||||||||||||||||||||||
income before benefit from income taxes | -8,638,000 | |||||||||||||||||||||||||||||||||||||
benefit from income taxes | -2,580,000 | |||||||||||||||||||||||||||||||||||||
cost of product sales | 2,290,928 | 1,923,831 | 982,836 | |||||||||||||||||||||||||||||||||||
interest income | -2,257,474 | -1,343,439 | -272,962.25 | -551,002 | ||||||||||||||||||||||||||||||||||
general and administrative | 25,703,731 | 18,826,587 | 20,226,884 | 16,344,361 | 11,248,372 | 10,359,507 | 6,331,308 | 5,222,899 | 3,111,662 | 2,445,077 | 2,818,392 | 2,299,083 | 2,202,679 | 2,439,061 | 2,410,699 | 1,950,210 | 1,826,290 | 1,743,377 | 1,686,814 | 1,818,789 | 1,639,026 | 1,529,220 | 1,356,613 | |||||||||||||||
balance at december 31, 2020 | 37,374,088 | |||||||||||||||||||||||||||||||||||||
stock-based compensation | ||||||||||||||||||||||||||||||||||||||
issuance of common stock upon exercise of options | 94,000 | |||||||||||||||||||||||||||||||||||||
issuance of common stock upon vesting of rsus | 1,917 | |||||||||||||||||||||||||||||||||||||
issuance of common stock upon financing | 93,877 | |||||||||||||||||||||||||||||||||||||
balance at march 31, 2021 | 37,563,882 | |||||||||||||||||||||||||||||||||||||
balance at december 31, 2021 | 37,816,794 | |||||||||||||||||||||||||||||||||||||
shares tendered for withholding taxes | ||||||||||||||||||||||||||||||||||||||
balance at march 31, 2022 | 38,883,445 | |||||||||||||||||||||||||||||||||||||
interest and amortization of debt discount income | -1,081,991.5 | -1,475,535 | -1,436,522 | -1,415,909 | ||||||||||||||||||||||||||||||||||
loss on extinguishment of debt | -1,247,012 | |||||||||||||||||||||||||||||||||||||
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tax credit | 139,448 | 217,418 | 207,114 | |||||||||||||||||||||||||||||||||||
interest and amortization of debt discount | -215,180.75 | -327,825 | -313,995 | -218,903 | -219,651.25 | -270,933 | -292,323 | -315,349 | ||||||||||||||||||||||||||||||
change in fair value of warrant liability | 102,000 | 15,000 | 1,000 | 2,673,000 | ||||||||||||||||||||||||||||||||||
interest and amortization of debt discount/premium income | -249,954.5 | -343,234 | -333,578 | -323,006 | 16,924 | |||||||||||||||||||||||||||||||||
interest and other income | 11,308.25 | 13,219 | 15,090 | |||||||||||||||||||||||||||||||||||
change in fair value of embedded derivative liabilities |
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