7Baggers

ANI Pharmaceuticals, Inc
(NASDAQ:ANIP) 

ANIP stock logo

ANI Pharmaceuticals, Inc., a specialty pharmaceutical company, develops, manufactures, and markets branded and generic prescription pharmaceuticals in the United States and Canada. It focuses on producing controlled substances, oncology products, hormones and steroids, and other formulations. The co...

Founded: 2001
Full Time Employees: 338
Sector: Healthcare
Industry: Drug Manufacturers-Specialty & Generic

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Quarterly
Annual
    Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 2014-06-30 2014-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31 2010-12-31 2010-09-30 2010-06-30 2010-03-31 2009-12-31 2009-09-30 2009-06-30 2009-03-31 2008-12-31 2008-09-30 2008-06-30 2008-03-31 2007-12-31 2007-09-30 2007-06-30 2007-03-31 2006-12-31 2006-09-30 2006-06-30 2006-03-31 2005-12-31 2005-09-30 2005-08-29 2005-06-30 2000-09-30 
                                                                                          
      net revenues
    237,462,000 247,060,000 227,813,000 211,371,000 197,122,000 190,574,000 148,332,000 138,040,000 137,430,000 131,654,000 131,829,000 116,547,000 106,786,000 94,232,000 83,821,000 73,855,000 64,477,000 60,929,000 52,061,000 48,625,000 54,521,000 57,252,000 52,979,000 48,470,000 49,774,000 47,966,000 51,337,000 54,357,000 52,887,000 57,122,000 50,703,000 47,268,000 46,483,000 47,286,000 48,164,000 44,764,000 36,628,000 38,205,000 38,525,000 31,337,000 20,555,000 18,035,000 19,972,000 19,516,000 18,799,000 21,037,000 17,387,000 6,647,000 10,899,000 10,532,330 7,836,222 6,151,539                                   
      operating expenses
                                                                                          
      cost of sales
    93,582,000 100,269,000 93,389,000 74,615,000 73,037,000 80,280,000 63,075,000 57,698,000 49,157,000 53,420,000 48,101,000 42,284,000 37,708,000 36,326,000 32,894,000 35,294,000 34,271,000 33,898,000 24,413,000 22,314,000 19,985,000 15,654,250 20,118,000 20,695,000 21,804,000 11,339,750 15,002,000 15,632,000 14,725,000 13,222,750 15,605,000 16,593,000 20,693,000 14,646,500 21,078,000 21,122,000 16,386,000 16,906,000 16,669,000 11,795,000 3,410,000 3,540,000 3,260,000 3,141,000 2,751,000 3,673,000 3,061,000 2,117,000 2,622,000 2,907,805 2,629,119 2,098,540                                   
      research and development
    10,600,000 12,261,000 12,304,000 16,535,000 10,564,000 16,646,000 10,128,000 7,296,000 10,511,000 9,867,000 11,121,000 7,374,000 5,924,000 5,222,000 7,657,000 4,165,000 5,274,000 3,140,000 2,456,000 2,805,000 2,968,000 3,079,500 2,939,000 3,035,000 6,344,000 3,782,000 4,982,000 5,773,000 4,373,000 2,976,500 4,667,000 5,137,000 2,102,000 1,604,750 2,634,000 2,167,000 1,618,000 135,000 1,041,000 764,000 966,000 661,000 815,000 995,000 403,000 568,000 883,000 851,000 376,000 524,539 453,897 437,184 972,049 2,434,742 3,872,736 5,398,305 5,183,217 6,701,127 11,500,053 11,116,323 14,864,420 11,905,433 9,716,091 8,657,606 9,426,870 3,743,967 3,371,217 3,493,576 3,072,240 3,855,464 5,322,472 3,934,118 2,677,946 1,211,919 1,145,764 1,347,361 913,852 955,943 766,592 1,114,588 1,018,877 1,015,228 1,314,283  1,927,890  
      selling, general, and administrative
    73,655,000 82,790,000 76,656,000 81,771,000 76,528,000 69,719,000 79,075,000 52,821,000 48,021,000 44,462,000 42,007,000 38,760,000 36,468,000 33,188,000 30,081,000 31,958,000 28,817,000 30,706,000 17,181,000 18,820,000 17,587,000 12,655,250 15,725,000 21,213,000 13,683,000 10,457,250 14,357,000 14,188,000 13,284,000 7,671,750 11,769,000 9,962,000 8,956,000 5,673,750 8,022,000 7,380,000 7,293,000 7,369,000 6,928,000 7,628,000 5,904,000                                              
      depreciation and amortization
    20,919,000 22,613,000 22,632,000 23,281,000 22,891,000 22,600,000 15,748,000 14,697,000 14,686,000 15,194,000 15,207,000 14,690,000 14,700,000 14,484,000 14,167,000 13,764,000 14,557,000 13,684,000 11,346,000 11,324,000 10,898,000 8,434,750 11,358,000 11,198,000 11,183,000 8,762,000 9,473,000 9,472,000 16,103,000 6,264,000 8,548,000 8,313,000 8,195,000 5,226,500 7,099,000 7,101,000 6,706,000 5,812,000 5,966,000 5,956,000 4,609,000 2,111,000 2,047,000 1,415,000 1,327,000 1,282,000 1,187,000 706,000 703,000 437,172 381,699 146,523 166,386 171,452 25,749 30,933 30,866 29,868 35,670 40,519 41,944 39,033 41,000 42,546 45,421 41,113 33,308 33,333 29,246 9,159 11,759 12,309 9,773 10,491 17,993 28,600 32,916 32,709 30,725 27,109 27,457 24,489 25,464  26,043  
      contingent consideration fair value adjustment
    -182,000 -5,727,000 -14,470,000 1,277,000 -12,092,000 -1,893,000 825,000 359,000 90,000 1,985,000 -2,555,000 1,035,000 961,000 1,624,000 2,476,000 -1,095,000 753,000                                                                      
      total operating expenses
    198,574,000 212,293,000 191,573,000 197,479,000 170,928,000 194,952,000 168,851,000 132,871,000 117,118,000 124,928,000 113,881,000 104,145,000 96,891,000 92,412,000 88,816,000 86,768,000 83,672,000 84,652,000 55,623,000 64,178,000 51,476,000 56,921,000 50,177,000 59,777,000 57,616,000 52,637,000 44,009,000 45,065,000 48,485,000 45,677,000 40,589,000 40,005,000 39,946,000 39,907,000 38,833,000 37,770,000 32,003,000 36,907,000 30,604,000 26,143,000 14,889,000 11,767,000 11,521,000 11,102,000 9,232,000 10,265,000 9,188,000 9,107,000 7,404,000 7,072,507 7,025,931 9,926,373                                   
      operating income
    38,888,000 34,767,000 36,240,000 13,892,000 26,194,000 -4,378,000 -20,519,000 5,169,000 20,312,000 6,726,000 17,948,000 12,402,000 9,895,000 1,820,000 -4,995,000 -12,913,000 -19,195,000 -23,723,000 -3,562,000 -15,553,000 3,045,000 -4,086,750 2,802,000 -11,307,000 -7,842,000 5,255,500 7,328,000 9,292,000 4,402,000 5,978,500 10,114,000 7,263,000 6,537,000 5,237,500 9,331,000 6,994,000 4,625,000 1,298,000 7,921,000 5,194,000 5,666,000 6,608,000 8,451,000 8,414,000 9,567,000 2,308,500 8,199,000 -2,460,000 3,495,000                                      
      yoy
    48.46% -894.13% -276.62% 168.76% 28.96% -165.09% -214.32% -58.32% 105.28% 269.56% -459.32% -196.04% -151.55% -107.67% 40.23% -16.97% -730.38% 480.49% -227.12% 37.55% -138.83% -177.76% -61.76% -221.69% -278.15% -12.09% -27.55% 27.94% -32.66% 14.15% 8.39% 3.85% 41.34% 303.51% 17.80% 34.66% -18.37% -80.36% -6.27% -38.27% -40.78% 186.25% 3.07% -442.03% 173.73%                                          
      qoq
    11.85% -4.06% 160.87% -46.96% -698.31% -78.66% -496.96% -74.55% 201.99% -62.53% 44.72% 25.34% 443.68% -136.44% -61.32% -32.73% -19.09% 566.00% -77.10% -610.77% -174.51% -245.85% -124.78% 44.19% -249.22% -28.28% -21.14% 111.09% -26.37% -40.89% 39.25% 11.11% 24.81% -43.87% 33.41% 51.22% 256.32% -83.61% 52.50% -8.33% -14.26% -21.81% 0.44% -12.05% 314.42% -71.84% -433.29% -170.39%                                       
      operating margin %
    Infinity% Infinity% Infinity% Infinity% Infinity% -Infinity% -Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% Infinity% -Infinity% Infinity% -Infinity% -Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% -Infinity% Infinity% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% 
      other income
    -651,000 850,000 -853,000 1,739,000 198,000     -33,000 -39,000 -53,000  -42,000 37,000 764,000     -515,000   -116,000 10,000 -29,250 -33,000 46,000  -17,750 20,000   14,500 95,000  -18,000 -43,000 -21,000 -12,000 2,000 1,000 -28,000  68,000 88,000 82,000  29,000 -84,098.25 147,563        2,000 13,000                  13,750  55,000   32,000    
      unrealized gain on investment in equity securities
    5,753,000 273,000 3,140,000 332,000 -921,000 -1,991,000 1,355,000 -2,712,000 9,655,000                                                                              
      interest expense
    -3,769,000 -4,411,000 -4,727,000 -5,438,000 -5,484,000 -6,015,000 -2,331,000 -4,656,000 -4,600,000 -5,746,000 -6,398,000 -7,100,000 -7,696,000 -7,506,000 -7,264,000 -6,669,000 -6,613,000 -4,440,000 -2,497,000 -2,531,000 -2,454,000 -1,724,500 -2,510,000 -2,356,000 -2,032,000 -2,524,000 -3,336,000 -3,406,000 -3,354,000 -2,783,000 -3,768,000 -3,730,000 -3,634,000 -2,252,250 -3,052,000 -3,025,000 -2,932,000 -2,859,000 -2,856,000 -2,830,000 -2,782,000    -2,725,000     -98  -374,476                                   
      income before income tax expense
    40,221,000 16,078,000 33,800,000 10,525,000 19,987,000 -2,112,500 -31,498,000 -2,287,000 25,335,000                                                                              
      income tax expense
    10,729,000 3,989,000 7,183,000 1,976,000 4,306,000 -3,486,000 -7,332,000  7,128,000                                                                  -75,000  75,000          
      net income
    29,492,000 27,490,000 26,617,000 8,549,000 15,681,000 -10,276,000 -24,166,000 -2,287,000 18,207,000 1,155,000 9,940,000 6,245,000 1,439,000 -4,243,000 -8,600,000 -14,923,000 -20,130,000 -24,136,000 -4,447,000 -14,106,000 86,000 -4,728,250 434,000 -12,336,000 -7,011,000 2,732,250 3,895,000 6,585,000 449,000 2,516,000 5,037,000 2,777,000 2,250,000 2,138,250 4,720,000 2,681,000 1,152,000 -1,080,000 2,543,000 1,125,000 1,346,000 2,876,000 4,559,000 3,571,000 4,369,000 21,005,000 6,746,000 -2,363,000 3,359,000 3,432,929 1,191,043 -4,583,266 -2,290,649 -3,987,592 -6,121,815 -7,344,116 -10,264,477 -6,648,401 -12,733,691 -14,975,231 -17,250,676 -13,271,519 -11,589,711 -10,794,351 -10,540,419 -32,486,130 -6,370,556 -4,620,701 -4,050,612 -1,165,211 -6,585,084 -6,048,067 -3,626,638 -1,673,629 -1,693,044 -2,400,309 -1,817,018 8,989,456 -745,061 -2,224,900       
      yoy
    88.07% -367.52% -210.14% -473.81% -13.87% -989.70% -343.12% -136.62% 1165.25% -127.22% -215.58% -141.85% -107.15% -82.42% 93.39% 5.79% -23506.98% 410.46% -1124.65% 14.35% -101.23% -273.05% -88.86% -287.33% -1661.47% 8.59% -22.67% 137.13% -80.04% 17.67% 6.72% 3.58% 95.31% -297.99% 85.61% 138.31% -14.41% -137.55% -44.22% -68.50% -69.19% -86.31% -32.42% -251.12% 30.07% 511.87% 466.39% -48.44% -246.64% -186.09% -119.46% -37.59% -77.68% -40.02% -51.92% -50.96% -40.50% -49.90% 9.87% 38.73% 63.66% -59.15% 81.93% 133.61% 160.22% 2688.00% -3.26% -23.60% 11.69% -30.38% 288.95% 151.97% 99.59% -118.62% 127.24% 7.88%           
      qoq
    7.28% 3.28% 211.35% -45.48% -252.60% -57.48% 956.67% -112.56% 1476.36% -88.38% 59.17% 333.98% -133.91% -50.66% -42.37% -25.87% -16.60% 442.75% -68.47% -16502.33% -101.82% -1189.46% -103.52% 75.95% -356.60% -29.85% -40.85% 1366.59% -82.15% -50.05% 81.38% 23.42% 5.23% -54.70% 76.05% 132.73% -206.67% -142.47% 126.04% -16.42% -53.20% -36.92% 27.67% -18.27% -79.20% 211.37% -385.48% -170.35% -2.15% 188.23% -125.99% 100.09% -42.56% -34.86% -16.64% -28.45% 54.39% -47.79% -14.97% -13.19% 29.98% 14.51% 7.37% 2.41% -67.55% 409.94% 37.87% 14.07% 247.63% -82.31% 8.88% 66.77% 116.69% -1.15% -29.47% 32.10% -120.21% -1306.54% -66.51%        
      net income margin %
    Infinity% Infinity% Infinity% Infinity% Infinity% -Infinity% -Infinity% -Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% Infinity% -Infinity% Infinity% -Infinity% -Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% -Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% Infinity% -Infinity% Infinity% Infinity% Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% Infinity% -Infinity% -Infinity% NaN% NaN% NaN% NaN% NaN% NaN% 
      dividends on series a convertible preferred stock
      -344,000 -407,000 -406,000 -406,000 -406,000 -407,000 -406,000 -406,000 -406,000 -407,000 -406,000 -407,000 -406,000 -407,000 -405,000                                                                      
      net income available to common shareholders
    29,492,000 27,490,000 26,273,000 8,142,000 15,275,000 -10,682,000 -24,572,000 -2,694,000 17,801,000 749,000 9,534,000 5,838,000 1,033,000    -20,535,000                                                                      
      basic and diluted income per share:
                                                                                          
      basic income per share
    1.31 1.24 1.19 0.37 0.7 -0.55 -1.27 -0.14 0.84 0.02 0.46 0.3 0.06                                                                          
      diluted income per share
    1.28 1.17 1.13 0.36 0.69 -0.55 -1.27 -0.14 0.82 0.02 0.45 0.29 0.06                                                                          
      basic weighted-average shares outstanding
    20,914 20,053 20,074 19,834 19,607 19,318 19,404 19,321 19,099 18,001 18,883 17,688 16,392 16,260 16,303 16,272 16,137 12,596 12,107 12,085 12,004  11,991 11,967 11,902  11,879 11,851 11,747  11,706 11,679 11,589  11,553 11,546 11,527 11,445 11,465 11,402 11,395 11,370 11,384 11,344 11,326 10,941 11,235 11,233 9,991                                      
      diluted weighted-average shares outstanding
    21,544 21,228 21,093 20,308 20,046 19,318 19,404 19,321 19,422 18,194 19,125 17,855 16,531 16,260 16,303 16,272 16,137 12,596 12,107 12,085 12,017  12,003 11,967 11,902  12,085 12,269 11,823  11,804 11,789 11,706  11,677 11,667 11,653 11,573 11,625 11,541 11,489 11,557 11,563 11,549 11,562 11,053 11,302 11,233 10,001                                      
      loss on disposal of assets
     87,000 295,000                                                                                    
      intangible asset impairment charge
      767,000             112,000                                                                       
      other expense
         -663,750 -2,535,000 -88,000 -32,000    -34,000    -89,000 -2,690,000 -1,071,000 -67,000  -83,750 -229,000      -130,000   -30,000 -61,000   -19,000            -39,000    -433,956                                   
      loss on extinguishment of debt
          -7,468,000                                                                                
      gain on sale of building
            -5,347,000                                                                              
      restructuring activities
               2,000 1,130,000 1,568,000 1,541,000 2,570,000                                                                       
      income before income tax benefit
             4,731,250 11,511,000 5,249,000 2,165,000                                                                          
      income tax benefit
             -325,250 -1,571,000 996,000 -726,000                                     20,713 82,852   209 121,791                                
      legal settlement expense
                     350,000  8,400,000                                                                   
      purified cortrophin gel pre-launch charges
                      227,000                                                                    
      loss before benefit for income taxes
                 -5,728,000 -12,222,000 -18,818,000    -18,151,000                                                                   
      benefit for income taxes
                 1,485,000 3,622,000 3,895,000 5,767,000 6,717,000 2,683,000 4,045,000 10,000 -1,253,000 371,000 1,443,000 2,853,000 2,817,000 -64,000 653,000                  10,945,000 -1,545,000 133,000                                       
      net loss available to common shareholders
                 -4,650,000 -9,006,000 -15,330,000                                                                       
      basic and diluted loss per share:
                                                                                          
      basic loss per share
                 -0.29 -0.55 -0.94    -1.17                                                                   
      diluted loss per share
                 -0.29 -0.55 -0.94    -1.17                                                                   
      income before benefit for income taxes
                    -25,897,000 -30,853,000 -7,130,000  76,000 -5,895,000 63,000 -13,779,000 -9,864,000 2,702,250 3,959,000 5,932,000                                                           
      basic and diluted earnings per share:
                                                                                          
      basic earnings per share
                    -1.27 -1.87 -0.37  0.01 -0.395 0.04 -1.03 -0.59 0.228 0.32 0.55 0.04 0.213 0.43 0.24 0.19 0.185 0.41 0.23 0.1 -0.1 0.22 0.1 0.12 0.273 0.4 0.31 0.38 0.178 0.59 -0.21 0.33                                      
      diluted earnings per share
                    -1.27 -1.87 -0.37  0.01 -0.395 0.04 -1.03 -0.59 0.223 0.32 0.53 0.04 0.213 0.42 0.23 0.19 0.183 0.4 0.23 0.1 -0.09 0.22 0.1 0.12 0.268 0.39 0.31 0.38 0.175 0.59 -0.21 0.33                                      
      cortrophin pre-launch charges
                       515,000 38,000 2,068,750 37,000 3,636,000 4,602,000 48,750 195,000                                                            
      operating expenses:
                                                                                          
      income before provision for income taxes
                                918,000 3,177,750 6,366,000 3,503,000 2,842,000 2,999,750 6,374,000 3,950,000 1,675,000 2,570,500 5,044,000 2,352,000 2,886,000 4,558,000 5,657,000  6,910,000 2,329,750 8,291,000 -2,496,000 3,524,000                                      
      provision for income taxes
                                -469,000 -661,750 -1,329,000 -726,000 -592,000 -861,500 -1,654,000 -1,269,000 -523,000 -1,317,000 -2,501,000 -1,227,000 -1,540,000 -1,433,250 -1,098,000  -2,541,000    -165,000                                      
      selling, general and administrative
                                             3,925,250 5,399,000 5,551,000 4,751,000 4,742,000 4,057,000 5,433,000 3,703,000 12,126,818 1,750,734 1,457,845                                   
      interest income
                                             -2,060,000 -2,766,000 -2,749,000  3,250 10,000 3,000     1,860 1,325 1,877 1,431 1,992 1,618 1,516 1,711 3,245 1,366.5 5,466                        
      income before provision for/benefit from income taxes
                                               5,665,000                                           
      benefit from income taxes
                                               -2,094,000                                           
      net income from continuing operations
                                                 21,005,000 6,746,000   3,388,266 1,040,706 -4,583,266                                   
      discontinued operation
                                                      0.02                                    
      gain on discontinued operation, net of provision for income taxes
                                                                                          
      computation of income from continuing operations attributable
                                                                                          
      to common stockholders and participating securities:
                                                                                          
      preferred stock dividends
                                                     -801  -2,370,028                                   
      income from continuing operations attributable to common stockholders and participating securities
                                                 21,005,000 6,746,000                                        
      continuing operations
                                                 1.9 0.59   1.35 0.11 -6.02                                   
      computation of income attributable to common stockholders:
                                                                                          
      income attributable to common stockholders
                                                   -2,363,000 3,359,000                                      
      salaries and benefits
                                                     2,174,909.5 1,729,066 5,713,504                                   
      freight
                                                     56,047.25 81,416 72,777                                   
      operating income from continuing operations
                                                     3,459,823 810,291 -3,774,834                                   
      net income from continuing operations before income tax benefit
                                                     -841,279.5 957,854 -4,583,266                                   
      gain on discontinued operation, net of tax
                                                     37,584.25 150,337                                    
      computation of income from continuing operationsattributable to common stockholders:
                                                                                          
      income from continuing operations attributable to common stockholders
                                                     -2,064,116.25 1,040,706                                    
      basic and diluted income per share
                                                     1.35 0.13                                    
      basic and diluted weighted-average shares outstanding
                                                     5,071 9,480,206 1,155,093                                   
      discontinued operations
                                                                                          
      gain on discontinued operations, net of tax
                                                                                          
      computation of income from continuing operations attributable to common stockholders:
                                                                                          
      loss from continuing operations attributable to common stockholders
                                                       -6,953,294                                   
      basic and diluted loss per share
                                                       -6.02                                   
      revenue
                                                                                          
      yoy
                                                                                          
      qoq
                                                                                          
      royalty revenue
                                                        145,040 83,290.75 110,383 108,780 114,000 55,196.75 82,784 81,003 57,000 26,665 51,331  2,228,004 1,051,066  85,449 5,485 3,781 3,734 11,081 15,404 2,009 14,063 52,928           
      revenue - sum
                                                        145,040 83,290.75 110,383 108,780 114,000 80,196.75 182,784  57,000 582,801.25 51,331  2,279,874 48,520.75 10,492 115,163 68,428 42,769.5 82,212 25,869 62,997 40,961.75 43,793 69,446 50,608 100,063.5 140,324 175,251 84,679 96,971 87,106  45,596  
      expenses
                                                                                          
      general and administration
                                                        1,949,114 2,902,289 1,546,864 1,948,995 1,831,852 1,724,147 1,675,268 1,989,103 1,593,557 1,367,131 1,534,417 1,540,200 1,498,252 1,629,786 1,506,056 1,208,956 1,029,202 767,535 1,438,816 1,593,156 1,325,493 1,119,241 1,027,194 1,181,377 771,589 -377,183 210,552 1,328,612 2,223,019 849,920 704,966  775,174  
      expenses - sum
                                                        3,087,549 4,967,379.25 5,445,349 7,378,233 7,045,935 10,714,214.5 13,210,991 13,145,945 16,499,921 8,192,788.25 11,291,508 10,240,352 11,239,293 3,811,900.25 6,381,048  4,130,688 4,081,460.5 6,773,047 5,539,583 4,013,212 1,707,587.25 2,190,951 2,700,243 1,939,155 1,721,882.75 1,007,869  3,409,353      
      other
                                                                                          
      convertible note fair value adjustment
                                                           15,953   463,000                            
      gain on sale of intellectual property
                                                        1,000,000                                  
      basic and diluted net loss per share
                                                        -0.09 -0.285 -0.27 -0.36 -0.09 -0.12 -0.12 -0.16 -0.2 -0.128 -0.16 -0.17 -0.19 -0.133 -0.21 -0.17 -0.15 -0.15 -0.24                
      weighted-average number of shares outstanding
                                                        24,487,451  22,921,176 20,202,737 116,266,613  104,439,220 93,985,347 84,764,512  71,194,180  56,312,814 33,952 30,434,050  27,434,050  27,380,217   25,486             
      licensing revenue
                                                             25,000 100,000           3,374,909  4,546 4,545 149,000 9,091 6,818 34,091          
      loss before income tax benefit
                                                                                          
      grant revenue
                                                                 130   51,870 12,851 10,492 29,714 62,943 8,028 21,082 10,242 25,648 12,144 20,639 9,700 16,517          
      investment impairment loss
                                                                                          
      other revenue
                                                                         223,204 57,396  17,400              
      acquisition related costs
                                                                     367,616.75 1,470,467                    
      licensing expense
                                                                 250   268,750                      
      fair value adjustment
                                                                  103,000                        
      weighted average number of shares outstanding
                                                                   64,607,893    27,434,050  27,307        21,191    19,392,116     
      other - impairment of short term investments
                                                                         165,050  660,200               
      other - interest income
                                                                     2,912   11,648 138,793.75 105,751 125,847 323,577 189,032.75 379,114 230,488 146,529 72,205.25 122,484 70,158 96,179 96,923 104,390  101,926  
      net loss before income tax expense
                                                                                          
      net loss before income
                                                                                          
      tax expense
                                                                           -6,048,067 -3,626,638 -1,477,592.75 -1,768,044 -2,400,309 -1,742,018          
      basic and diluted net loss
                                                                                          
      per share
                                                                           -0.22 -0.13 -0.06 -0.06 -0.1 -0.08 -0.075 -0.03 -0.11       
      weighted average number
                                                                                          
      of shares outstanding
                                                                           27,232,272 27,185,893 6,232,170.5 27,137,431 23,870,950 23,367,493 5,118,095.75 22,412,189 19,551,980 19,426,895 4,847,490 19,399,086  19,385,086  
      see accompanying notes to the condensed financial statements.
                                                                                          
      see accompanying notes to the financial statements.
                                                                                          
      stock compensation expense
                                                                               142,905 220,798          
      licensing income
                                                                                 25,568.25 34,091 34,091 34,091 34,091 11,364    
      grant income
                                                                                 60,745.25 106,233 86,160 50,588 62,880 43,742  45,596  
      loss on disposal of capital assets
                                                                                          
      costs of acquisition of structured biologicals inc.
                                                                                          
      purchassed in-process research and development
                                                                                          
      provision for contingencies
                                                                                    140,000      
      purchased in-process research
                                                                                          
      and development
                                                                                          
      purchased in-process research and development
                                                                                          
      costs of acquisition of structured
                                                                                          
      biologicals inc.
                                                                                          
      biologicals inc.-
                                                                                          
      and development-
                                                                                          
    Balance Sheets:
    Quarterly
    Annual
      Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 2014-06-30 2014-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31 2010-12-31 2010-09-30 2010-06-30 2010-03-31 2009-12-31 2009-09-30 2009-06-30 2009-03-31 2008-12-31 2008-09-30 2008-06-30 2008-03-31 2007-12-31 2007-09-30 2007-06-30 2007-03-31 2006-12-31 2006-09-30 2006-06-30 2006-03-31 2005-12-31 2005-09-30 2005-06-30 
                                                                                          
        assets
                                                                                          
        current assets
                                                                                          
        cash and cash equivalents
      311,176,000 285,585,000 262,610,000 217,797,000 149,802,000 144,861,000 144,982,000 240,110,000 228,597,000 221,121,000 193,078,000 161,707,000 67,757,000 48,228,000 56,281,000 63,385,000 76,911,000 100,300,000 15,254,000 24,261,000 25,073,000 7,864,000 17,900,000 27,702,000 20,414,000 62,332,000 59,673,000 40,589,000 38,233,000 43,008,000 44,136,000 54,994,000 51,970,000 31,144,000 18,031,000 8,369,000 10,826,000 27,365,000 16,155,000 15,014,000 77,747,000 154,684,000 150,913,000 166,731,000 165,563,000 169,037,000 35,050,000 52,961,000 51,373,000 11,105,000 10,929,806 12,594,927 29,388,772 34,794,341 38,049,095 42,417,045 49,473,732 57,225,234 69,600,199 37,126,006 51,349,021 38,155,251 35,526,017 46,382,112 41,163,001 29,858,465 13,169,258 5,985,823 10,162,346 11,760,920 5,700,697 10,325,577 13,106,123 15,648,948 25,402,564 27,382,168 11,290,742 7,653,852 366,174 133,605 70,189 310,643 254,142 379,523 
        restricted cash
      36,000 36,000 36,000 36,000 34,000 33,000 35,000        5,003,000 5,001,000 5,000,000 5,001,000 5,001,000 5,001,000 5,000,000 5,003,000 5,003,000 5,002,000 5,002,000 5,029,000 5,025,000 5,018,000 5,008,000 5,021,000 5,014,000 5,007,000 5,002,000 5,006,000 5,004,000 5,002,000 5,001,000 5,002,000 5,001,000 5,001,000           2,260,100 2,260,100 2,260,100                                
        accounts receivable
      255,432,000                                                  9,515,096 6,427,506            53,156 132,748 64,645 38,271 117,333 356,751 229,775 82,531 21,292 30,218 14,566 3,599,764 3,577,339 3,514,711 10,510,529       
        inventories
      143,468,000 143,067,000 146,475,000 138,315,000 137,408,000 136,782,000 148,042,000 125,448,000 113,837,000 111,196,000 106,590,000 104,323,000 103,654,000 105,355,000 95,893,000 92,545,000 83,155,000 81,693,000 61,684,000 67,634,000 59,927,000 60,803,000 59,195,000 52,563,000 52,902,000 48,163,000 46,174,000 45,296,000 42,032,000 40,503,000 40,006,000 37,756,000 34,294,000 37,727,000 38,478,000 42,307,000 45,893,000 26,183,000 28,261,000 25,052,000 13,922,000 13,387,000 13,741,000 12,701,000 10,737,000 7,518,000 7,346,000 5,912,000 5,090,000 3,518,000 2,809,160 2,584,686                                 
        prepaid expenses and other current assets
      22,087,000 23,189,000 18,551,000 15,110,000 23,326,000 17,975,000 17,475,000 14,001,000 16,050,000 17,400,000 10,690,000 8,248,000 6,874,000 8,387,000 4,972,000 6,026,000 7,726,000 7,589,000 4,702,000 4,881,000 5,922,000 5,861,000 3,358,000 3,117,000 2,967,000 3,995,000 5,025,000 3,311,000 4,157,000 4,524,000 5,004,000 1,768,000 2,267,000 2,784,000 4,847,000 2,676,000 3,565,000 3,564,000 2,653,000 4,046,000 1,252,000 1,453,000 1,985,000 1,615,000 1,546,000 1,983,000                                       
        investment in equity securities
      14,885,000 9,131,000 8,859,000 5,718,000 5,386,000 6,307,000 8,298,000 6,943,000 9,655,000                                                                            
        total current assets
      747,084,000 753,117,000 698,402,000 602,630,000 536,290,000 527,684,000 521,297,000 555,460,000 540,557,000 519,816,000 497,220,000 459,311,000 364,753,000 344,261,000 309,377,000 322,399,000 301,399,000 321,775,000 191,384,000 191,799,000 182,798,000 170,321,000 165,819,000 156,544,000 158,662,000 187,695,000 182,386,000 168,912,000 151,832,000 152,877,000 156,793,000 152,367,000 143,394,000 131,605,000 125,582,000 112,856,000 106,981,000 103,007,000 95,475,000 79,824,000 116,552,000 192,583,000 197,522,000 208,948,000 202,993,000 203,478,000 57,565,000 67,160,000 67,936,000 27,716,000 26,094,759 24,118,984                                 
        non-current assets
                                                                                          
        property and equipment
      67,115,000 62,476,000 63,560,000 59,247,000 58,179,000 56,863,000 56,704,000 51,640,000 48,526,000 44,593,000 44,189,000 44,371,000 70,553,000 75,958,000 72,935,000 71,042,000 77,677,000 75,627,000 60,816,000 60,336,000 59,541,000 41,269,000 40,444,000 39,937,000 40,353,000 40,551,000 39,754,000 38,953,000 38,425,000 38,090,000 37,418,000 22,842,000 21,882,000 20,403,000 17,387,000 14,966,000 12,897,000 10,998,000 9,716,000 8,911,000 8,415,000 7,131,000 5,833,000 5,249,000 5,281,000 5,223,000    4,537,000    166,386 1,184,764 862,439 884,301 861,364 854,989 1,132,519 812,962 635,776 646,500 683,800 710,395 747,979 720,403 752,970 786,303 814,894 529,301 162,481 59,748 54,896 43,783 58,520 104,124 137,040 169,529 164,906 188,629 215,566 218,555 241,806 
        deferred tax assets
      66,555,000                                                                                    
        intangible assets
      467,161,000 479,526,000 499,817,000 520,320,000 538,495,000 541,834,000 569,825,000 183,078,000 196,044,000 209,009,000 219,828,000 230,299,000 238,791,000 251,635,000 264,237,000 269,593,000 281,573,000 294,122,000 170,141,000 180,199,000 178,859,000 188,511,000 198,620,000 205,745,000 215,619,000 180,388,000 188,372,000 196,697,000 205,100,000 201,604,000 209,544,000 217,484,000 221,917,000 229,790,000 189,829,000 196,624,000 203,459,000 175,792,000 188,949,000 194,674,000 147,386,000 66,397,000 68,291,000 44,174,000 45,408,000 42,067,000 43,188,000 21,800,000 22,360,000 10,409,000 10,712,273 10,960,000                                 
        goodwill
      62,480,000 62,480,000 62,480,000 60,533,000 60,662,000 59,990,000 60,426,000 28,221,000 28,221,000 28,221,000 28,221,000 28,221,000 28,221,000 28,221,000 28,221,000 28,221,000 28,188,000 27,888,000 3,580,000 3,580,000 3,580,000 3,580,000 3,580,000 3,580,000 3,580,000 3,580,000 3,580,000 3,580,000 3,580,000 3,580,000 4,180,000 1,838,000 1,838,000 1,838,000 1,838,000 1,838,000 1,838,000 1,838,000 1,838,000 1,838,000 1,838,000 1,838,000 1,838,000 1,838,000 1,838,000 1,838,000 1,838,000 1,838,000 1,838,000 1,838,000 1,838,309 1,838,309                                 
        other non-current assets
      11,575,000                 2,205,000 626,000 720,000 833,000 802,000 985,000 1,095,000 1,110,000 1,220,000 1,656,000 1,789,000 1,903,000                                                        
        total assets
      1,421,970,000 1,440,377,000 1,408,152,000 1,343,001,000 1,292,428,000 1,283,697,000 1,287,377,000 920,753,000 914,524,000 904,422,000 889,914,000 859,341,000 765,224,000 760,087,000 739,110,000 751,334,000 744,846,000 771,598,000 470,454,000 480,159,000 463,843,000 461,190,000 462,581,000 465,391,000 482,232,000 456,789,000 456,775,000 446,906,000 434,390,000 430,604,000 439,443,000 424,177,000 418,019,000 412,138,000 370,469,000 359,219,000 357,138,000 322,864,000 319,379,000 307,999,000 291,588,000 285,265,000 283,276,000 270,121,000 265,985,000 263,709,000 107,637,000 95,423,000 96,652,000 44,500,000 43,285,828 41,658,023                                 
        liabilities and stockholders’ equity
                                                                                          
        current liabilities
                                                                                          
        current debt
      19,298,000                                                                                    
        accounts payable
      69,694,000 62,583,000 69,795,000 54,569,000 53,058,000 45,656,000 60,890,000 48,681,000 49,430,000 36,683,000 34,077,000 28,505,000 32,687,000 29,305,000 18,992,000 27,641,000 22,059,000 22,967,000 11,513,000 12,977,000 13,769,000 11,261,000 13,460,000 14,209,000 12,485,000 14,606,000 10,953,000 9,809,000 10,519,000 8,884,000 7,257,000 7,949,000 4,886,000 3,630,000 5,821,000 3,153,000 4,785,000 3,389,000 4,730,000 4,961,000 3,040,000 2,066,000 2,633,000 1,325,000 2,288,000 2,654,000 3,059,000 1,731,000 2,660,000 1,429,000 2,086,847 1,634,788 164,352 1,128,644 2,004,814 3,835,756 3,281,705 3,150,677 6,041,891 6,348,948 8,503,790 4,864,217 4,522,800 4,719,457 4,002,557 2,440,096 3,529,203 2,550,227 2,429,446 3,182,089 3,420,066 2,619,915 2,301,248 710,575 559,380 888,751 643,845 621,818 318,254 669,734 1,380,026 1,139,566 518,473 782,495 
        accrued royalties
      33,926,000 48,497,000 51,247,000 36,030,000 23,713,000 22,626,000 23,447,000 20,357,000 15,475,000 16,276,000 11,975,000 9,885,000 8,957,000 9,307,000 6,585,000 6,295,000 4,998,000 6,225,000 3,996,000 4,688,000 5,310,000 6,407,000 6,088,000 6,004,000 6,285,000 5,084,000 5,527,000 6,265,000 5,440,000 8,456,000 7,455,000 8,219,000 11,361,000 12,164,000 11,741,000 11,255,000 10,331,000 11,956,000 11,769,000 8,110,000 4,632,000 606,000                                           
        accrued compensation and related expenses
      16,091,000 37,897,000 33,221,000 32,933,000 22,297,000 37,725,000 29,777,000 16,111,000 9,526,000 23,786,000 15,328,000 11,493,000 13,051,000 10,312,000 7,745,000 5,682,000 3,265,000 8,522,000 4,539,000 4,319,000 5,533,000 6,231,000 5,993,000 5,349,000 3,151,000 3,736,000 3,494,000 2,133,000 2,454,000 3,524,000 2,773,000 1,410,000 1,495,000 2,306,000 2,009,000 1,227,000 1,135,000 1,631,000 1,426,000 1,071,000 722,000 1,188,000 1,019,000 844,000 513,000 1,348,000                                       
        accrued government rebates
      38,417,000 43,154,000 37,032,000 32,866,000 22,644,000 18,714,000 10,693,000 12,324,000 9,509,000 12,168,000 10,923,000 11,971,000 8,607,000 10,872,000 8,745,000 9,440,000 4,557,000 5,492,000 11,713,000 8,740,000 8,672,000 7,826,000 11,678,000 9,717,000 8,030,000 8,901,000 9,184,000 10,943,000 8,552,000 8,974,000 9,014,000 5,256,000 6,471,000 7,930,000 5,755,000 3,534,000 4,655,000 5,891,000                                               
        income taxes payable
      5,297,000 1,291,000  3,294,000 14,188,000 6,749,000   11,402,000 8,164,000 594,000                                                                          
        returned goods reserve
      43,052,000 49,504,000 50,005,000 48,683,000 42,464,000 39,274,000 37,068,000 33,897,000 32,853,000 29,678,000 31,438,000 29,798,000 34,108,000 33,399,000 33,984,000 34,899,000 35,554,000 35,831,000 32,229,000 31,904,000 28,944,000 27,155,000 23,250,000 20,003,000 17,614,000 16,595,000 15,945,000 14,656,000 13,559,000 12,552,000 10,840,000 9,764,000 9,020,000 8,274,000 8,317,000 7,558,000 5,776,000 5,756,000 4,099,000 3,309,000 2,666,000 2,648,000 1,889,000 1,719,000 1,817,000 1,445,000 1,178,000 951,000 849,000 736,000 457,890 349,763                                 
        accrued expenses and other
      13,735,000 16,803,000 13,951,000 14,761,000 12,029,000 13,735,000 17,814,000 6,917,000 7,430,000 5,606,000 5,228,000 5,338,000 4,804,000 5,394,000 4,726,000 11,505,000 8,133,000 7,563,000 4,893,000 11,582,000 2,381,000 2,456,000 2,534,000 3,066,000 4,378,000 2,362,000 3,368,000 2,423,000 3,074,000 1,707,000 2,818,000 1,863,000 2,612,000 1,571,000 2,741,000 1,565,000 2,087,000 927,000 2,016,000 770,000 1,727,000 617,000 2,221,000 1,170,000 1,897,000 1,269,000                                       
        total current liabilities
      239,510,000 278,112,000 270,555,000 236,835,000 201,815,000 193,680,000 189,933,000 139,978,000 136,889,000 145,477,000 134,352,000 122,865,000 125,825,000 99,439,000 81,627,000 96,312,000 79,532,000 87,537,000 84,872,000 89,454,000 82,768,000 78,565,000 75,900,000 79,088,000 79,356,000 61,676,000 170,707,000 166,794,000 165,068,000 165,549,000 46,902,000 39,678,000 39,650,000 39,228,000 36,384,000 28,292,000 32,425,000 31,948,000 30,491,000 24,730,000 16,211,000 11,756,000 12,190,000 6,949,000 9,073,000 13,233,000 8,145,000 3,828,000 4,560,000 3,538,000 6,597,023 6,163,213                       2,234,868 2,610,549 2,430,717 4,299,610 1,662,982 2,303,623 2,734,762 2,666,034 1,504,865  
        non-current liabilities
                                                                                          
        debt
      285,996,000                                                                                    
        convertible notes
      308,466,000                                                                                    
        contingent consideration
      9,248,000                                                                                    
        other non-current liabilities
      16,450,000 12,164,000 11,270,000 6,696,000 7,020,000 5,781,000 6,944,000 4,679,000 5,055,000 4,809,000 5,259,000 4,731,000 1,202,000           17,080,000 13,611,000 6,514,000 8,065,000 6,768,000 3,109,000                                                        
        total liabilities
      859,670,000 899,653,000 902,335,000 881,394,000 848,958,000 855,167,000 856,579,000 440,143,000 437,711,000 446,823,000 435,203,000 424,869,000 425,742,000 421,547,000 402,435,000 414,376,000 398,752,000 412,858,000 279,051,000 288,242,000 260,131,000 265,490,000 267,481,000 274,047,000 281,061,000 243,998,000 243,645,000 239,250,000 234,678,000 233,341,000 246,978,000 239,067,000 238,375,000 237,382,000 187,668,000 182,673,000 184,926,000 153,216,000 150,549,000 144,223,000 131,410,000 125,183,000 127,383,000 120,621,000 121,245,000 123,924,000       9,325,736 10,593,665 10,922,066 16,373,638 16,578,542 24,564,463 30,742,051 31,233,334 30,669,399 25,619,528 25,459,464 25,157,583 24,310,432 20,606,534            4,299,610 1,705,982 2,325,123 2,790,353 2,755,716 1,607,138  
        commitments and contingencies
                                                                                          
        stockholders’ equity
                                                                                          
        common stock, 0.0001 par value...
      3,000 3,000 3,000 2,000 2,000 2,000 2,000 2,000 2,000 2,000 2,000 2,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000  954                                 
        class c special stock, 0.0001 par value...
                                                                                          
        preferred stock, 0.0001 par value...
                                                                                          
        treasury stock
      -53,004,000 -33,249,000 -32,638,000 -31,594,000 -31,043,000 -21,040,000 -20,722,000 -20,042,000 -18,742,000 -10,081,000 -9,850,000 -9,180,000 -8,643,000 -5,094,000 -4,975,000 -4,736,000 -4,253,000 -3,135,000 -3,135,000 -3,062,000 -2,594,000 -2,246,000 -2,246,000 -2,246,000 -1,211,000 -723,000 -723,000 -723,000  -659,000 -659,000 -659,000 -250,000 -259,000 -259,000 -259,000        -113,000     -68,000 -68,000 -432,562 -432,562                                 
        additional paid-in capital
      608,429,000 596,036,000 586,230,000 541,899,000 531,055,000 519,653,000 510,899,000 532,497,000 523,628,000 514,103,000 506,513,000 495,488,000 408,395,000 403,901,000 399,396,000 395,043,000 391,084,000 387,844,000 222,211,000 219,403,000 216,223,000 214,354,000 211,792,000 209,409,000 203,505,000 200,800,000 197,470,000 194,867,000 189,971,000 186,812,000 186,532,000 184,531,000 181,649,000 179,020,000 177,436,000 175,901,000 173,989,000 172,563,000 170,665,000 168,154,000 165,681,000 164,431,000 163,118,000 161,397,000 160,095,000 159,509,000 140,221,000 139,070,000 137,272,000 89,501,000 89,024,878 89,021,927                                 
        retained earnings
      6,393,000                        10,565,000 17,584,000 22,419,000 18,524,000 11,939,000                                                        
        accumulated other comprehensive income, net of tax
      479,000 1,033,000 2,811,000 3,312,000 3,610,000 5,344,000 5,366,000 8,328,000 9,406,000 8,857,000 14,076,000 13,726,000 11,131,000 12,168,000 10,039,000 5,430,000 2,712,000              533,000 216,000                                                     
        total stockholders’ equity
      562,300,000 540,724,000 505,817,000 436,757,000 418,620,000 403,680,000 405,948,000 455,760,000 451,963,000 432,749,000 429,861,000 409,622,000 314,632,000 313,690,000 311,825,000 312,108,000 321,244,000 333,890,000 191,403,000 191,917,000 203,712,000 195,700,000 195,100,000 191,344,000                               32,289,680                              
        total liabilities and stockholders’ equity
      1,421,970,000                  470,454,000 480,159,000 463,843,000 461,190,000 462,581,000 465,391,000                                                             
        accounts receivable, net of 171,803 and 127,824 of adjustments for chargebacks and other allowances at december 31, 2025 and 2024, respectively
       281,082,000                                                                                   
        prepaid income taxes
       11,027,000 9,254,000    6,104,000 2,867,000    4,088,000 3,735,000 3,827,000 3,778,000 2,013,000 1,982,000 3,667,000 3,030,000 2,375,000   1,621,000   1,076,000 814,000 3,442,000    1,734,000 62,000 1,162,000 2,052,000 3,991,000   929,000 150,000 1,150,000 1,127,000 972,000 1,022,000                                         
        deferred tax assets, net of deferred tax liabilities and valuation allowance
       69,072,000 71,396,000 92,025,000 88,489,000 85,106,000 67,661,000 89,506,000 87,607,000 90,711,000 84,389,000 81,500,000 80,956,000 81,363,000 77,340,000 76,587,000 73,539,000 67,936,000 60,196,000 58,526,000 52,006,000 51,704,000 48,130,000 53,488,000 57,906,000 38,326,000 36,002,000 31,957,000 28,542,000 27,964,000 25,082,000 23,590,000                                                     
        derivatives and other non-current assets
       13,706,000 12,497,000 8,246,000 10,313,000 12,220,000 11,464,000 12,848,000 13,569,000 12,072,000 16,067,000 15,639,000 9,228,000 11,361,000 12,102,000 5,762,000 2,434,000                                                                    
        liabilities, mezzanine equity, and stockholders’ equity
                                                                                          
        current debt, net of deferred financing costs
       17,268,000 15,241,000 13,216,000 11,193,000 9,172,000 7,152,000 850,000 850,000 850,000 850,000 850,000 850,000 850,000 850,000 850,000 850,000 850,000 15,927,000 15,182,000 14,438,000 13,243,000 12,785,000 12,329,000 11,872,000                                                            
        income taxes payable - foreign
       948,000                                                                                   
        current contingent consideration
       167,000 63,000 483,000 229,000 29,000 1,283,000 841,000 414,000 12,266,000 23,939,000 25,025,000 22,761,000                                                                        
        non-current debt, net of deferred financing costs and current component
       291,840,000 297,677,000 301,484,000 305,294,000 309,108,000 312,918,000 284,394,000 284,607,000 284,819,000 285,032,000 285,244,000 285,457,000 285,669,000 285,882,000 286,095,000 286,307,000 286,520,000 186,063,000 189,525,000 168,985,000 172,443,000 175,161,000 177,879,000 188,094,000                                                            
        non-current convertible notes, net of deferred financing costs
       307,927,000 307,392,000 306,862,000 306,335,000 305,812,000 305,293,000                                                                              
        accrued licensor payments due
        4,062,000 11,428,000 11,068,000 20,961,000                                                                               
        non-current contingent consideration, net of current
       9,610,000 11,379,000 18,089,000 17,426,000 19,825,000    11,718,000                                                                           
        mezzanine equity
                                                                                          
        convertible preferred stock, series a, 0.0001 par value...
         24,850,000 24,850,000 24,850,000 24,850,000 24,850,000 24,850,000 24,850,000 24,850,000 24,850,000 24,850,000 24,850,000 24,850,000 24,850,000 24,850,000 24,850,000                                                                   
        accumulated deficit
       -23,099,000 -50,589,000 -76,862,000 -85,004,000 -100,279,000 -89,597,000 -65,025,000 -62,331,000 -80,132,000 -80,880,000 -90,414,000 -96,252,000 -97,286,000 -92,636,000 -83,630,000 -68,300,000 -47,765,000 -23,439,000 -18,992,000 -4,886,000            -1,756,000 -4,006,000   -1,778,000 -2,916,000 -1,836,000 -4,379,000 -5,504,000 -4,350,000 -7,226,000 -11,785,000 -15,356,000 -19,725,000 -40,730,000 -47,476,000 -45,113,000 -48,472,000 -51,904,465 -53,095,509              -119,434,428      -64,156,187 -58,108,120 -54,481,482 -52,807,418 -51,114,374 -48,714,065        
        total liabilities, mezzanine equity, and stockholders’ equity
       1,440,377,000 1,408,152,000 1,343,001,000 1,292,428,000 1,283,697,000 1,287,377,000 920,753,000 914,524,000 904,422,000 889,914,000 859,341,000 765,224,000 760,087,000 739,110,000 751,334,000 744,846,000 771,598,000                                                                   
        accounts receivable, net of 125,165 and 127,824 of adjustments for chargebacks and other allowances at september 30, 2025 and december 31, 2024, respectively
        252,617,000                                                                                  
        accounts receivable, net of 120,421 and 127,824 of adjustments for chargebacks and other allowances at june 30, 2025 and december 31, 2024, respectively
         225,654,000                                                                                 
        accounts receivable, net of 139,655 and 127,824 of adjustments for chargebacks and other allowances at march 31, 2025 and december 31, 2024, respectively
          220,334,000                                                                                
        accounts receivable, net of 127,824 and 97,262 of adjustments for chargebacks and other allowances at december 31, 2024 and 2023, respectively
           221,726,000                                                                               
        assets held for sale
               8,020,000 8,020,000 8,020,000 8,020,000 8,020,000 8,020,000 8,020,000                                                                     
        accounts receivable, net of 91,008 and 97,262 of adjustments for chargebacks and other allowances at september 30, 2024 and december 31, 2023, respectively
            196,361,000                                                                              
        accrued licensor payment
            1,809,000                                                                              
        non-current contingent consideration
            20,175,000 11,092,000 11,160,000  10,560,000 12,029,000 13,258,000 35,058,000 33,434,000 30,958,000 32,053,000 31,000,000                                                                   
        accrued licensor payment, net of current
            21,316,000                                                                              
        accounts receivable, net of 102,784 and 97,262 of adjustments for chargebacks and other allowances at june 30, 2024 and december 31, 2023, respectively
             166,091,000                                                                             
        accounts receivable, net of 91,825 and 97,262 of adjustments for chargebacks and other allowances at march 31, 2024 and december 31, 2023, respectively
              172,418,000                                                                            
        current restricted cash
                   5,006,000                                                                       
        accounts receivable, net of 97,262 and 161,052 of adjustments for chargebacks and other allowances at december 31, 2023 and 2022, respectively
               162,079,000                                                                           
        accounts receivable, net of 97,774 and 161,052 of adjustments for chargebacks and other allowances at september 30, 2023 and december 31, 2022, respectively
                178,842,000                                                                          
        accounts receivable, net of 89,427 and 161,052 of adjustments for chargebacks and other allowances at june 30, 2023 and december 31, 2022, respectively
                 172,925,000                                                                         
        accounts receivable, net of 112,950 and 161,052 of adjustments for chargebacks and other allowances at march 31, 2023 and december 31, 2022, respectively
                  174,713,000                                                                        
        accumulated depreciation
                  -27,278,000 -32,712,000 -30,105,000 -27,271,000 -24,964,000 -22,956,000 -21,290,000 -20,002,000 -18,774,000                                                                
        accounts receivable, net of 161,052 and 105,260 of adjustments for chargebacks and other allowances at december 31, 2022 and 2021, respectively
                   165,438,000                                                                       
        non-current restricted cash
                                                                                          
        derivatives and other non-current liabilities
                   1,381,000 1,492,000 1,011,000 860,000 7,801,000 8,116,000 9,263,000 8,378,000 14,482,000 16,420,000                                                              
        accounts receivable, net of 111,000 and 105,260 of adjustments for chargebacks and other allowances at september 30, 2022 and december 31, 2021, respectively
                    140,433,000                                                                      
        accounts receivable, net of 150,428 and 105,260 of adjustments for chargebacks and other allowances at june 30, 2022 and december 31, 2021, respectively
                     150,410,000                                                                     
        accounts receivable, net of 113,970 and 105,260 of adjustments for chargebacks and other allowances at march 31, 2022 and december 31, 2021, respectively
                      131,625,000                                                                    
        deferred revenue
                      116,000 87,000 62,000 62,000 62,000 80,000 112,000 125,000 318,000 451,000 496,000 558,000 624,000 711,000 735,000                20,000 13,000 38,000 47,000 46,712 46,712                     4,545 9,091 18,182 27,273 34,091 68,182 102,273 136,363 136,363 136,363 136,363  
        accounts receivable, net of 105,260 and 100,328 of adjustments for chargebacks and other allowances at december 31, 2021 and december 31, 2020, respectively
                       128,526,000                                                                   
        current income taxes payable
                          3,659,000 3,906,000  8,286,000 15,223,000    3,453,000 5,022,000 318,000      3,656,000 2,398,000       481,000 4,253,000                                       
        accumulated other comprehensive loss, net of tax
                       -3,055,000 -4,235,000 -5,433,000 -5,032,000 -11,437,000 -13,110,000 -14,049,000 -11,689,000 -4,871,000 -6,037,000 -5,013,000 -2,199,000 -379,000                                                       
        accounts receivable, net of 108,456 and 100,328 of adjustments for chargebacks and other allowances at september 30, 2021 and december 31, 2020, respectively
                        106,714,000                                                                  
        accounts receivable, net of 92,130 and 100,328 of adjustments for chargebacks and other allowances at june 30, 2021 and december 31, 2020, respectively
                         92,648,000                                                                 
        accounts receivable, net of 80,722 and 100,328 of adjustments for chargebacks and other allowances at march 31, 2021 and december 31, 2020, respectively
                          91,876,000                                                                
        accounts receivable, net of 100,328 and 59,946 of adjustments for chargebacks and other allowances at december 31, 2020 and 2019, respectively
                           95,793,000                                                               
        (accumulated deficit)/retained earnings
                           -4,972,000 -1,337,000 -1,771,000                                                             
        accounts receivable, net of 86,418 and 59,946 of adjustments for chargebacks and other allowances at september 30, 2020 and 2019, respectively
                            83,745,000                                                              
        accounts receivable, net of 72,469 and 59,946 of adjustments for chargebacks and other allowances at june 30, 2020 and 2019, respectively
                             73,162,000                                                             
        accounts receivable, net of 104,711 and 59,946 of adjustments for chargebacks and other allowances at march 31, 2020 and december 31, 2019, respectively
                              82,379,000                                                            
        liabilities and stockholders' equity
                                                                                          
        stockholders' equity
                                                                                          
        total stockholders' equity
                              201,171,000 212,791,000 213,130,000 207,656,000 199,712,000 197,263,000 192,465,000 185,110,000 179,644,000 174,756,000 182,801,000 176,546,000 172,212,000 169,648,000 168,830,000 163,776,000 160,178,000 160,082,000 155,893,000 149,500,000 144,740,000 139,785,000 99,492,000 91,595,000 92,092,000                                    
        total liabilities and stockholders' equity
                              482,232,000 456,789,000 456,775,000 446,906,000 434,390,000 430,604,000 439,443,000 424,177,000 418,019,000 412,138,000 370,469,000 359,219,000 357,138,000 322,864,000 319,379,000 307,999,000 291,588,000 285,265,000 283,276,000 270,121,000 265,985,000 263,709,000 107,637,000 95,423,000 96,652,000                                    
        accounts receivable, net of 59,946 and 47,705 of adjustments for chargebacks and other allowances at december 31, 2019 and 2018, respectively
                               72,129,000                                                           
        current component of term loan and delayed draw term loan, net of deferred financing costs
                               9,941,000                                                           
        convertible notes, net of discount and deferred financing costs
                                117,586,000 115,858,000 114,150,000 112,463,000 134,122,000 132,127,000 130,156,000 128,208,000 126,284,000 124,381,000 122,501,000 120,643,000 118,808,000 116,993,000 115,199,000 113,427,000                                           
        term loan and delayed draw term loan, net of deferred financing costs and current component
                               175,808,000                                                           
        accounts receivable, net of 47,687 and 47,705 of adjustments for chargebacks and other allowances at september 30, 2019 and december 31, 2018, respectively
                                70,700,000                                                          
        current component of term loan, net of deferred financing costs
                                4,154,000 4,149,000                                                         
        term loan, net of deferred financing costs and current component
                                64,873,000 65,688,000                                                         
        accounts receivable, net of 46,301 and 47,705 of adjustments for chargebacks and other allowances at june 30, 2019 and december 31, 2018, respectively
                                 76,274,000                                                         
        accounts receivable, net of 48,849 and 47,705 of adjustments for chargebacks and other allowances at march 31, 2019 and december 31, 2018, respectively
                                  67,410,000                                                        
        current component of non-current borrowing, net of deferred financing costs
                                  3,243,000                                                        
        non-current borrowing, net of deferred financing costs and current borrowing component
                                  66,501,000                                                        
        accounts receivable, net of 47,705 and 34,686 of adjustments for chargebacks and other allowances at december 31, 2018 and 2017, respectively
                                   64,842,000                                                       
        other long-term assets
                                   1,468,000 1,412,000 1,049,000 823,000 829,000                                                   
        current component of long-term borrowing, net of deferred financing costs
                                   3,256,000 5,692,000 5,217,000 3,805,000 3,353,000                                                   
        long-term liabilities
                                                                                          
        long-term borrowing, net of deferred financing costs and current borrowing component
                                   67,296,000 65,954,000 67,262,000 68,569,000 69,946,000                                                   
        other long-term liabilities
                                   496,000                                                       
        retained earnings/
                                   11,488,000 6,058,000 1,021,000   5,623,000 903,000                                                 
        accounts receivable, net of 50,603 and 34,686 of adjustments for chargebacks and other allowances at september 30, 2018 and december 31, 2017, respectively
                                    67,647,000                                                      
        accounts receivable, net of 58,439 and 34,686 of adjustments for chargebacks and other allowances at june 30, 2018 and december 31, 2017, respectively
                                     56,115,000                                                     
        accounts receivable, net of 30,786 and 34,686 of adjustments for chargebacks
                                                                                          
        and other allowances at march 31, 2018 and december 31, 2017, respectively
                                      54,801,000                                                    
        deferred tax asset, net of valuation allowance
                                      23,163,000 22,667,000 30,829,000 27,933,000 26,962,000 26,227,000 18,400,000 17,751,000 17,397,000 17,316,000  7,027,000 7,369,000 7,796,000                                       
        accounts receivable, net of 34,686 and 31,535 of adjustments for chargebacks and other allowances at december 31, 2017 and 2016, respectively
                                       58,788,000                                                   
        long-term royalties
                                           625,000 1,250,000 2,500,000                                             
        accounts receivable, net of 32,463 and 31,535 of adjustments for chargebacks and other allowances at september 30, 2017 and december 31, 2016, respectively
                                        62,174,000                                                  
        borrowings on line of credit
                                        25,000,000 30,000,000                                                 
        accounts receivable, net of 39,050 and 31,535 of adjustments for chargebacks and other allowances at june 30, 2017 and december 31, 2016, respectively
                                         55,513,000                                                 
        accounts receivable, net of 29,481 and 31,535 of adjustments for chargebacks and other allowances at march 31, 2017 and december 31, 2016, respectively
                                          46,697,000                                                
        line of credit
                                          30,000,000                                                
        accounts receivable, net of 31,535 and 13,586 of adjustments for chargebacks and other allowances at december 31, 2016 and 2015, respectively
                                           45,895,000                                               
        accounts receivable, net of 22,385 and 13,586 of adjustments for chargebacks and other allowances at september 30, 2016 and december 31, 2015, respectively
                                            47,477,000                                              
        accrued medicaid rebates
                                            6,451,000 6,509,000 3,424,000 4,631,000 4,428,000 1,891,000 2,077,000 2,264,000                                       
        accounts receivable, net of 23,406 and 13,586 of adjustments for chargebacks and other allowances at june 30, 2016 and december 31, 2015, respectively
                                             35,562,000                                             
        accounts receivable, net of 13,630 and 13,586 of adjustments for chargebacks and other allowances at march 31, 2016 and december 31, 2015, respectively
                                              22,481,000                                            
        accounts receivable, net of 13,586 and 8,708 of adjustments for chargebacks and other allowances at december 31, 2015 and 2014, respectively
                                               21,932,000                                           
        accounts receivable, net of 9,980 and 8,708 of adjustments for chargebacks and other allowances at september 30, 2015 and december 31, 2014, respectively
                                                21,645,000                                          
        deferred tax assets, net of valuation allowance
                                                8,266,000 7,999,000 7,776,000 7,643,000                                       
        deferred financing costs
                                                2,674,000 2,885,000 3,096,000 3,307,000                                       
        convertible notes, net of discount
                                                115,193,000 113,672,000 112,172,000 110,691,000                                       
        accounts receivable, net of 7,724 and 8,708 of adjustments for chargebacks and other allowances at june 30, 2015 and december 31, 2014, respectively
                                                 18,880,000                                         
        accounts receivable, net of 8,096 and 8,708 of adjustments for chargebacks and other allowances at march 31, 2015 and december 31, 2014, respectively
                                                  17,371,000                                        
        accounts receivable, net of 8,708 and 5,104 of adjustments for chargebacks and other allowances at december 31, 2014 and 2013, respectively
                                                   17,297,000                                       
        accounts receivable, net of 8,100 and 5,104 of allowances for chargebacks and other allowances at september 30, 2014 and december 31, 2013, respectively
                                                    14,570,000                                      
        prepaid expenses
                                                    599,000 493,000 566,000 580,000 580,597 251,765               1,011,099 836,505                 
        property, plant, and equipment
                                                    5,046,000 4,625,000 4,518,000                                    
        accrued expenses
                                                    3,888,000 1,133,000 1,013,000 1,326,000 1,338,215 1,039,393                                 
        accounts receivable, net of 7,694 and 5,104 of allowances for chargebacks and other allowances at june 30, 2014 and december 31, 2013, respectively
                                                     7,794,000                                     
        accounts receivable, net of 4,874 and 5,104 of allowances for chargebacks and other allowances at march 31, 2014 and december 31, 2013, respectively
                                                      10,907,000                                    
        accounts receivable, net of 5,104 and 6,124 of adjustments for chargebacks and other allowances at december 31, 2013 and 2012, respectively
                                                       12,513,000                                   
        deferred loan costs
                                                                                          
        liabilities and stockholders' equity/
                                                                                          
        borrowings under line of credit
                                                                                          
        redeemable convertible preferred stock
                                                                                          
        stockholders' equity/
                                                                                          
        total stockholders' equity/
                                                       40,962,000 36,688,805 35,494,810                                 
        total liabilities and stockholders' equity/
                                                       44,500,000 43,285,828 41,658,023                                 
        land
                                                        86,949 86,949                                 
        buildings
                                                        3,682,006 3,682,006                                 
        machinery, furniture and equipment
                                                        3,736,484 3,724,427                                 
        construction in progress
                                                        197,948 176,276                                 
        property and equipment - sum
                                                        7,703,387 7,669,658                                 
        less: accumulated depreciation
                                                        3,062,900 2,928,928                                 
        total property and equipment
                                                        4,640,487 4,740,730                                 
        other assets
                                                                                          
        total other assets
                                                        12,550,582 12,798,309                                 
        accrued compensation
                                                        2,535,746 2,726,167 879,385 1,078,683 463,942 1,031,624 767,672 1,597,329 1,476,036 1,072,972 743,643 526,022 1,156,638 887,817 602,346 529,066 759,245 285,084 241,488 290,583 878,555 712,626 511,324 717,409 569,831 391,913 289,604 368,522 361,570 324,813 223,579 492,980 610,195 493,448 
        current liabilities, discontinued operation
                                                        131,613 366,390                                 
        10% convertible preferred stock, series a, 0.10 par value, stated value of 100
                                                                                          
        per share; no shares authorized, issued, or outstanding at september 30, 2013;
                                                                                          
        108,494 shares authorized, 102,774 shares issued and outstanding including cumulative dividends of 2,186,326 at december 31, 2012
                                                                                          
        10% convertible preferred stock, series b, 0.10 par value, stated value of 110
                                                                                          
        118,915 shares authorized, 78,491 shares issued and outstanding including cumulative dividends of 1,836,734 at december 31, 2012
                                                                                          
        12% convertible preferred stock, series c, 0.10 par value, stated value of 110
                                                                                          
        37,956 shares authorized, 34,810 shares issued and outstanding including cumulative dividends 994,471 at december 31, 2012
                                                                                          
        10% convertible preferred stock, series d, 0.10 par value, stated value of 30
                                                                                          
        3,400,000 shares authorized, 2,375,312 shares issued and outstanding including cumulative dividends of 4,184,858 at december 31, 2012
                                                                                          
        total redeemable convertible preferred stock
                                                                                          
        shares issued and 9,480,206 shares outstanding at september 30, 2013; 4,070,373 shares issued and outstanding at december 31, 2012
                                                        954                                  
        shares issued and outstanding at september 30, 2013 and december 31, 2012
                                                                                          
        10% convertible preferred stock, series a, 0.10 par value, stated value of 100 per share; no shares authorized, issued, or outstanding at june 30, 2013; 108,494 shares authorized, 102,774 shares issued and outstanding including cumulative dividends of 2,186,326 at december 31, 2012
                                                                                          
        10% convertible preferred stock, series b, 0.10 par value, stated value of 110 per share; no shares authorized, issued, or outstanding at june 30, 2013; 118,915 shares authorized, 78,491 shares issued and outstanding including cumulative dividends of 1,836,734 at december 31, 2012
                                                                                          
        12% convertible preferred stock, series c, 0.10 par value, stated value of 110 per share; no shares authorized, issued, or outstanding at june 30, 2013; 37,956 shares authorized, 34,810 shares issued and outstanding including cumulative dividends 994,471 at december 31, 2012
                                                                                          
        10% convertible preferred stock, series d, 0.10 par value, stated value of 30 per share; no shares authorized, issued, or outstanding at june 30, 2013; 3,400,000 shares authorized, 2,375,312 shares issued and outstanding including cumulative dividends of 4,184,858 at december 31, 2012
                                                                                          
        prepaid expenses and other assets
                                                          277,874 378,803 534,037 512,640 716,920 801,147 943,710 1,013,315 1,137,540 2,469,879 1,150,798 883,188 1,156,514 1,487,160   1,133,012 1,070,051 998,210 677,330 336,156 337,420           
        current assets - sum
                                                          31,926,746 35,173,144 38,583,132 42,929,685 50,190,652 58,026,381 70,543,909 38,139,321 52,486,561 40,625,130 36,676,815 47,318,456 42,452,263 31,410,270 14,218,628 7,733,059 11,652,109 16,087,080 18,551,812 23,454,040 27,944,547 31,006,910 33,346,262 35,071,415 18,918,939 22,208,474 10,540,224 4,712,909 7,282,763 9,346,996 10,565,289 12,250,938 
        investments
                                                          3,413,762 3,413,762 3,413,762 3,413,762 3,413,762 3,405,807 3,405,807 3,405,807 3,405,807 3,405,807 3,340,000 3,626,000 3,626,000 3,626,000                   
        deposits
                                                          15,878 15,878 30,088 88,793 86,203 86,203 86,203 86,203 99,937 99,937 99,937 154,937 527,463 652,679 879,956 903,442 637,397 637,397 600,797 573,097 573,097 39,536           
        other accrued expenses
                                                          112,784 502,452 860,094 1,028,623 2,035,576 2,479,697 2,747,791 2,872,081 2,235,633 1,681,956 1,415,693 1,082,976 1,608,223 942,922 480,909 865,011 428,905 374,887 266,979 283,849 102,750 77,712 68,500 128,500 175,236 65,500 192,651 282,713 104,794 147,125 239,834 274,753 
        current portion of convertible senior notes
                                                          8,169,215 7,883,886 7,593,216 10,477,635   1,234,000 1,187,497 1,149,820 1,111,132                       
        capital stock
                                                                                          
        issued and outstanding
                                                                                          
        2013 - 65,211; 2012 - 65,211 class c special stock
                                                          391                                
        2013 - 24,422,240; 2012 - 24,422,240 common stock
                                                          273,277,795                                
        issued and outstanding - sum
                                                          273,278,186 273,132,392 273,259,236 265,768,782 265,500,001 255,054,440 254,739,100 209,387,067 209,017,188 184,777,766 167,662,697 167,394,808 152,980,536 135,264,822 98,130,289 86,390,922 86,068,355 85,733,079 85,565,418 84,864,443 84,500,713 84,206,974 83,987,921 83,659,086 65,331,737 64,968,278 64,915,872  57,668,430 56,653,617 56,653,617 56,653,618 
        current liabilities - sum
                                                           10,593,665 10,922,066 16,373,638 6,084,953 7,227,703 11,499,718 11,481,498 12,632,886 8,183,327 7,095,131 6,690,250 6,225,015 3,930,117 4,777,228 3,716,522 3,104,726 3,852,952 4,570,263 3,621,362 2,926,799 1,515,850          1,550,696 
        long-term convertible senior notes
                                                              10,493,589 17,336,760 19,242,333 19,751,836 18,036,513 17,436,201                       
        2012 - 65,211; 2011 - 65,214 class c special stock
                                                           391 65 65                             
        2012 - 24,422,240; 2011 - 18,269,754 common stock
                                                           273,132,001                               
        2012 - 24,422,240; 2011 - 18,269,755 common stock
                                                            273,259,171                              
        2012 - 20,137,526 ; 2011 - 18,269,755 common stock
                                                             265,768,717                             
        2012 - 391,286; 2011 - 391,286 class c special stock
                                                              391                            
        2012 - 120,826,861; 2011 - 109,618,529 common stock
                                                              265,499,610                            
        2011 - 391,286; 2010 - 391,286 class c special stock
                                                               391 391 391 391                        
        2011 - 109,618,529; 2010 - 81,391,130 common stock
                                                               255,054,049 254,738,709                          
        2011 - 93,600,446; 2010 - 81,391,130 common stock
                                                                 209,386,676                         
        2011 - 93,590,612; 2010 - 81,391,130 common stock
                                                                  209,016,797                        
        2010 - 391,286; 2009 - 391,286 class c special stock
                                                                   391 391 391 391                    
        2010 - 81,391,130; 2009 - 53,262,568 common stock
                                                                   184,777,375                       
        due to licensor - antares
                                                                      11,889  7,871 16,200 4,887 5,393 4,663 4,972 6,932  881,328 898,818 875,000 2,625,000       
        convertible senior notes due 2011 and 2013
                                                                    18,364,333 18,467,333 18,085,417 16,676,417                   
        2010 - 70,802,894; 2009 - 53,262,568 common stock
                                                                    167,662,306 167,394,417                     
        2010 - 63,667,194; 2009 - 53,262,568 common stock
                                                                      152,980,145                    
        short-term investments
                                                                           3,026,334 11,770,374 12,429,841 14,472,050 15,005,976 3,952,633 3,903,529 3,856,965 3,795,977 9,903,757 4,371,626 6,984,609 8,790,888 10,045,355 11,692,960 
        due to licensor — antares
                                                                       18,033        1,063           
        2009 — 391,286; 2008 — 391,286 class c special stock
                                                                       391                   
        2009 — 53,262,568; 2008 — 27,042,764 common stock
                                                                       135,264,431                   
        investment in matc
                                                                        140,000 140,000 140,000 140,000 140,000 140,000 140,000 140,000           
        2009 - 391,286; 2008 - 391,286 class c special stock
                                                                        391 391 391                
        2009 - 33,042,764; 2008 - 27,042,764 common stock
                                                                        98,129,898                  
        deferred acquisition costs
                                                                         793,398                 
        2009 - 27,042,764; 2008 - 27,042,764 common stock
                                                                         86,390,531 86,067,964                
        2008 - 391,286; 2007 - 391,286 class c special stock
                                                                           391 391 391 391            
        2008 - 27,042,764; 2007 - 26,794,607 common stock
                                                                           85,732,688 85,565,027              
        accumulated other comprehensive income
                                                                            427,500              
        2008 - 26,881,950; 2007 - 26,794,607 common stock
                                                                             84,864,052             
        see accompanying notes to the condensed financial statements.
                                                                                          
        2008 - 26,794,607; 2007 - 26,794,607 common stock
                                                                              84,500,322            
        accumulated other comprehensive loss
                                                                              -602,000            
        provision for contingencies
                                                                                  412,941 550,588    750,000   
        2007-391,286; 2006-391,286 class c special stock
                                                                               391           
        2007-26,794,607; 2006-22,975,040 common stock
                                                                               84,206,583           
        prepaid expenses and other sundry assets
                                                                                391,301 208,379 256,521 248,116 270,293 207,678 227,965 245,465 265,792 178,455 
        security deposits
                                                                                25,326 25,326 25,326 25,326 25,325 25,325 11,992 11,992   
        accrual for contingencies
                                                                                137,647 275,294   688,234 890,000 890,000    
        2007 - 391,286; 2006 - 391,286 class c special stock
                                                                                391 391 391        
        2007 - 26,787,273; 2006 - 22,975,040 common stock
                                                                                83,987,530          
        see accompanying notes to the financial statements.
                                                                                          
        2007 - 26,743,349; 2006 - 22,975,040 common stock
                                                                                 83,658,695         
        2007 - 23,027,540; 2006 - 22,975,040 common stock
                                                                                  65,331,346        
        long term liabilities
                                                                                          
        leasehold retirement liability
                                                                                    43,000 21,500 21,500 21,500   
        total long term liabilities
                                                                                    43,000 21,500 55,591 89,682   
        2006 - 391,286; 2005 - 391,286 class c special stock
                                                                                   391 398 398 398    
        2006 - 22,975,040; 2005 - 19,007,800 common stock
                                                                                   64,967,887 64,915,474      
        deferred unearned compensation
                                                                                          
        deficit accumulated during the development stage
                                                                                    -55,886,776      
        capital stock issued and outstanding
                                                                                          
        2006 - 19,160,694; 2005 - 19,007,800 common stock
                                                                                     57,719,334 57,668,032    
        capital stock issued and outstanding - sum
                                                                                     57,719,732     
        due to antares
                                                                                          
        2005 - 391,286; 2004 - 391,286 class c special stock
                                                                                       398   
        2005 - 19,007,800; 2004 - 18,955,181 common stock
                                                                                       56,653,219   
        deferred revenue - long term
                                                                                        102,273  
        commitments
                                                                                          
        391,286 (2004 - 391,286) class c special stock
                                                                                        398 398 
        19,007,800 (2004 - 18,955,181) common stock
                                                                                        56,653,219 56,653,220 
      Cashflow Statements:
      Quarterly
      Annual
        Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 2014-06-30 2014-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31 2010-12-31 2010-09-30 2010-06-30 2010-03-31 2009-12-31 2009-09-30 2009-06-30 2009-03-31 2008-12-31 2008-09-30 2008-06-30 2008-03-31 2007-12-31 2007-09-30 2007-06-30 2007-03-31 2006-12-31 2006-09-30 2006-06-30 2006-03-31 2005-12-31 
                                                                                          
          cash flows from operating activities
                                                                                          
          net income
        29,492,000 27,490,000 26,617,000 8,549,000 15,681,000 -10,276,000 -24,166,000 -2,287,000 18,207,000 1,155,000 9,940,000 6,245,000 1,439,000    -20,130,000    86,000 -3,635,000 434,000 -12,336,000 -7,011,000 -4,835,000 3,895,000 6,585,000 449,000 5,430,000 5,037,000 2,777,000 2,250,000 -9,629,000 4,720,000 2,681,000 1,152,000 -1,080,000 2,543,000 1,125,000 1,346,000 2,876,000 4,559,000 3,571,000 4,369,000 21,005,000 6,746,000 -2,363,000 3,359,000                                  
          adjustments to reconcile net income to net cash and cash equivalents from operating activities:
                                                                                          
          stock-based compensation
        10,191,000 9,768,000 9,691,000 9,602,000 8,868,000 7,061,000 7,485,000 7,864,000 6,934,000 5,621,000 5,444,000 5,249,000 4,338,000 3,737,000 3,869,000 3,756,000 3,237,000 2,968,000 2,808,000 2,844,000 1,869,000 2,393,000 2,383,000 5,736,000 2,424,000 2,444,000 2,470,000 2,593,000 1,710,000 1,828,000 1,795,000 1,782,000 1,377,000 1,422,000 1,475,000 1,807,000 1,386,000 1,380,000 1,365,000 2,217,000 1,105,000 1,139,000 1,120,000 1,029,000 568,000 704,000 693,000 1,979,000 47,000 33,049                                 
          deferred taxes
        2,515,000 2,356,000 18,800,000 -3,536,000 -3,383,000 -17,530,000 -5,588,000 -1,899,000 3,104,000 -8,346,000 -3,257,000 -910,000 773,000 -1,625,000 -2,250,000 -3,914,000 -7,464,000 -8,089,000 -1,989,000 -6,397,000 -279,000 -4,173,000 5,068,000 5,143,000 -19,243,000 -2,701,000 -3,728,000 -2,540,000 -165,000 -2,599,000 -1,594,000 -491,000 -496,000 8,162,000 -2,896,000 -971,000 -735,000 -7,827,000 -649,000 -354,000 -81,000 -1,932,000 -358,000 119,000 294,000                                      
          depreciation and amortization
        20,919,000 22,613,000 22,632,000 23,281,000 22,891,000 22,600,000 15,748,000 14,697,000 14,686,000 15,194,000 15,207,000 14,690,000 14,700,000 15,572,000 15,350,000 14,174,000 14,557,000 13,684,000 11,346,000 11,324,000 10,898,000 10,899,000 11,358,000 11,198,000 11,183,000 9,564,000 9,473,000 9,472,000 16,103,000 8,686,000 8,548,000 8,313,000 8,195,000 7,022,000 7,099,000 7,101,000 6,706,000 5,812,000 5,966,000 5,956,000 4,609,000 2,111,000 2,047,000 1,415,000 1,327,000 1,282,000 1,187,000 706,000 703,000 437,172 381,699 124,743 166,386 171,398 25,749 30,933 30,866 30,108 35,669 40,519 41,944 39,019 41,000 42,546 45,421 41,393 33,308 33,333 29,246 9,296 11,759 12,309 9,773 10,315 17,993 28,600 32,916 32,490 30,725 27,109 27,457 24,489 
          unrealized loss on investment in equity securities
        -5,753,000   -332,000 921,000                                                                              
          non-cash operating lease expense
        453,000 555,000 358,000 394,000 452,000 392,000 384,000 377,000 373,000 381,000 827,000                                                                        
          non-cash interest
        358,000 351,000 340,000 341,000 324,000 323,000 121,000 96,000 102,000 952,000 997,000 986,000 987,000 998,000 994,000 987,000 982,000 794,000 577,000 569,000 572,000 588,000                                                             
          contingent consideration fair value adjustment
        -182,000 -5,727,000 -14,470,000 1,277,000 -12,092,000 -1,893,000 825,000 359,000 90,000 1,985,000 -2,555,000 1,035,000 961,000 1,924,000 2,476,000 -1,095,000 753,000                                                                  
          changes in operating assets and liabilities:
                                                                                          
          accounts receivable
        25,528,000 -27,856,000 -26,965,000 -5,491,000 1,782,000 -25,513,000 8,438,000 6,327,000 -10,339,000 16,763,000 -5,918,000 1,789,000 -9,275,000 -25,005,000 9,977,000 -18,785,000 -3,099,000 5,373,000 -14,066,000 -772,000 3,917,000 -12,048,000 -10,583,000 9,217,000 -10,250,000 -1,429,000 5,574,000 -8,864,000 -2,568,000 2,805,000 -10,221,000 -1,314,000 3,987,000 3,386,000 -6,661,000 -8,816,000 -802,000 1,582,000 -11,915,000 -13,081,000 -549,000 -287,000 -2,765,000 -1,509,000 -74,000 -2,727,000 -6,776,000 3,113,000 1,606,000 -2,998,305 -3,087,590           53,156   94,334 79,062     8,926 -15,652 3,567,726 -4,953 -62,628 6,995,818      
          inventories
        -437,000 3,732,000 -8,160,000 -908,000 -625,000 -675,000 -6,360,000 -11,611,000 -2,641,000 -4,605,000 -2,268,000 -669,000 1,701,000 -9,462,000 -3,312,000 -9,390,000 -1,462,000 -5,549,000 5,950,000 1,947,000 876,000 -1,608,000 -5,206,000 362,000 3,693,000 -1,989,000 -878,000 -3,264,000 -1,529,000 -497,000 -53,000 -3,262,000 3,433,000 751,000 3,829,000 3,586,000 -2,810,000 2,078,000 -3,209,000 -272,000 -535,000 354,000 -1,040,000 -1,964,000 -3,219,000 -172,000 -902,000 -822,000 -1,572,000 -708,525 -224,474                                
          prepaid expenses and other assets
        2,687,000 -4,460,000 -6,454,000 9,835,000 -3,945,000 -1,693,000 2,045,000                                              100,928    84,227    1,332,339    455,862       -341,174 -532,297          
          accounts payable
        5,358,000 -7,235,000 13,766,000 3,076,000 5,549,000 -6,821,000 -3,079,000 -1,147,000 11,526,000 2,780,000 5,572,000 -3,905,000 3,105,000 10,065,000 -9,074,000 5,056,000 -1,009,000 9,770,000 -1,292,000 -774,000 2,462,000 -2,148,000 -811,000 1,997,000 -1,332,000 2,909,000 798,000 -673,000 2,005,000 1,216,000 -2,321,000 2,866,000 1,705,000 -2,075,000 2,423,000 -1,663,000 1,318,000 -1,486,000 -288,000 1,961,000 889,000 -897,000 1,249,000 -908,000 -471,000 -405,000 328,000 -929,000 1,231,000 -658,280 452,059                                
          accrued royalties
        -14,655,000 -2,750,000 15,217,000 12,317,000 1,087,000 -821,000 3,090,000 4,882,000 -801,000 9,637,000 -2,091,000 -227,000 -350,000 2,722,000 290,000 1,297,000 -1,227,000 2,144,000 -692,000 -622,000 -1,097,000 319,000 84,000 -281,000 1,201,000 -443,000 -738,000 825,000 -3,016,000 1,001,000 -764,000 -3,142,000 -803,000 423,000 -139,000 1,549,000 -2,250,000 187,000 3,659,000                                            
          income taxes
        14,087,000 472,000 -12,548,000                                                                                
          accrued government rebates
        -4,737,000 6,123,000 4,166,000 10,222,000 3,930,000 7,635,000 -1,631,000 2,814,000 -2,658,000 1,347,000 1,048,000 1,166,000 -2,265,000 2,127,000 -695,000 4,883,000 -935,000 -6,965,000 2,973,000 68,000 846,000 -3,852,000 1,961,000 1,687,000 -871,000 -283,000 -1,759,000 2,391,000 -422,000 -40,000 3,758,000 -1,215,000 -1,459,000 2,175,000 2,221,000 -1,121,000 -1,236,000                                              
          returned goods reserve
        -6,451,000 -502,000 1,322,000 6,220,000 3,189,000 4,806,000 77,000 1,045,000 3,174,000 -1,761,000 1,640,000 -4,314,000 713,000 -581,000 -915,000 -655,000 -248,000 1,412,000 337,000 2,962,000 1,792,000 3,913,000 3,048,000 2,389,000 1,019,000 650,000 1,289,000 1,097,000 1,007,000 1,712,000 1,076,000 744,000 746,000 -43,000 759,000 1,782,000 20,000                                              
          accrued expenses, accrued compensation, and other
        -20,998,000 5,623,000 1,821,000 11,859,000 -17,077,000 5,446,000 8,985,000 7,030,000 -13,077,000 4,451,000 4,981,000 -153,000 2,992,000 2,835,000 -4,926,000 5,631,000 -4,445,000 -4,170,000 -6,471,000 8,409,000 -1,406,000 278,000 111,000 2,332,000 -365,000 -826,000 2,241,000 -1,046,000 55,000                                                      
          net cash and cash equivalents from operating activities
        58,375,000 30,367,000 44,055,000 75,812,000 34,991,000 15,860,000 12,474,000 17,414,000 18,269,000 44,740,000 32,169,000 20,626,000 21,424,000 -4,400,000 3,623,000 -11,484,000 -18,942,000 -12,185,000 -5,402,000 241,000 20,668,000 -5,709,000 -1,614,000 20,880,000 1,710,000 4,803,000 21,793,000 4,744,000 14,291,000 27,232,000 8,319,000 8,593,000 22,930,000 15,805,000 17,084,000 1,000 6,529,000 12,082,000 1,084,000 3,337,000 10,969,000 4,702,000 10,236,000 1,206,000 1,120,000 10,741,000 4,159,000 1,954,000 5,179,000 -2,864,620 -1,631,392                                
          cash flows from investing activities
                                                                                          
          acquisition of product rights, intangible assets, and other related assets
        -5,250,000 -159,000 -60,000 -2,895,000 -17,372,000 -86,000                                                                             
          acquisition of property and equipment
        -6,074,000 -1,244,000 -6,103,000 -4,014,000 -2,474,000 -2,394,000 -4,812,000 -4,449,000 -4,581,000 -2,279,000 -1,739,000 -2,501,000 -2,349,000 -3,138,000 -2,468,000 -1,321,000 -1,949,000 -356,000 -571,000 -932,000 -698,000 -2,110,000 -1,761,000 -725,000 -1,539,000 -1,703,000 -1,523,000 -1,634,000 -1,775,000 -1,007,000 -1,372,000 -1,086,000 -2,278,000 -3,447,000 -2,480,000 -2,304,000 -2,138,000 -1,389,000 -1,089,000 -719,000 -1,369,000 -1,105,000 -768,000 -198,000 -112,000 -338,000 -411,000 -253,000 -118,000                                  
          net cash and cash equivalents from investing activities
        -11,324,000 -1,403,000 -6,163,000 -6,909,000 -19,846,000 -10,681,000 -398,522,000 -4,449,000 8,933,000 -4,779,000 -4,553,000 -6,826,000 -2,353,000 -3,142,000 -9,814,000 -604,000 -2,178,000 -82,213,000 -583,000 -21,950,000 -737,000 -2,119,000 -5,809,000 -2,848,000 -57,546,000 -1,374,000 -1,932,000 -3,958,000 -20,285,000 -407,000 -18,439,000 -6,255,000 -2,278,000 -50,115,000 -2,480,000 -2,304,000 -53,094,000 -1,390,000 -1,089,000 -66,032,000 -85,551,000 -1,105,000 -26,768,000 -198,000 -4,612,000 -338,000 -22,528,000 -253,000 -12,635,000 2,230,973 -33,729                                
          cash flows from financing activities
                                                                                          
          principal payments on borrowings
        -4,063,000 -4,063,000 -2,031,000                                                                                
          series a convertible preferred stock dividends paid
         -344,000 -407,000 -406,000 -406,000 -406,000 -407,000 -406,000 -406,000 -406,000 -407,000 -406,000 -407,000 -406,000 -407,000 -405,000                                                                  
          proceeds from stock option exercises and espp purchases
        2,202,000 38,000 9,790,000 1,242,000 2,534,000 1,700,000 1,192,000 1,005,000 2,591,000 1,969,000 5,581,000 1,289,000 157,000 768,000 484,000 203,000 3,000 1,733,000   169,000                                                            
          treasury stock purchases for restricted stock vests
        -19,755,000 -611,000 -1,044,000 -551,000 -10,003,000 -318,000 -680,000 -1,300,000 -8,661,000 -231,000 -670,000 -537,000 -3,549,000 -119,000 -239,000 -483,000 -1,118,000 -1,000 -73,000 -468,000 -348,000 -1,035,000 -488,000                                                          
          net cash and cash equivalents from financing activities
        -21,616,000 -4,636,000 6,345,000 -1,747,000 -9,906,000 -4,907,000 291,030,000 -1,452,000 -19,726,000 -11,918,000 3,755,000 80,150,000 -4,548,000 -508,000 -911,000    -3,022,000 20,898,000 -2,725,000 -2,208,000 -2,378,000 -10,744,000 13,891,000  -770,000 1,580,000 1,206,000  -731,000 691,000 170,000 47,425,000 -4,940,000 -153,000 30,025,000 518,000 1,146,000 -38,000 -2,355,000 174,000 714,000 160,000 18,000 123,584,000 458,000 -113,000 47,724,000 808,869                                
          effect of exchange rate changes on cash, cash equivalents and restricted cash
        156,000 -1,353,000 576,000 841,000 -297,000 -395,000                                                                             
          net change in cash, cash equivalents, and restricted cash
        25,591,000 22,975,000 44,813,000 67,997,000 4,942,000 -123,000 -95,093,000 11,513,000 7,476,000  31,371,000 93,950,000 14,523,000                                                                      
          cash, cash equivalents, and restricted cash, beginning of period
        285,621,000  144,894,000  221,121,000  53,234,000 105,301,000 12,867,000 67,361,000 48,029,000 36,150,000 32,367,000                                              
          cash, cash equivalents, and restricted cash end of period
        311,212,000  44,813,000 67,997,000 149,836,000                                                                              
          reconciliation of cash, cash equivalents, and restricted cash, beginning of period
                                                                                          
          cash and cash equivalents
        285,585,000       221,121,000  48,228,000 100,300,000 7,864,000 62,332,000  43,008,000 31,144,000 27,365,000                                              
          restricted cash
        36,000          5,006,000 5,001,000 5,003,000 5,029,000 5,021,000 5,006,000 5,002,000                                              
          reconciliation of cash, cash equivalents, and restricted cash, end of period
                                                                                          
          cash, cash equivalents, and restricted cash, end of period
        311,212,000          31,371,000 93,950,000 67,757,000 -8,050,000 -7,102,000 -13,525,000 81,911,000 85,046,000 -9,007,000 -811,000 30,073,000 -10,036,000 -9,801,000 7,288,000 25,416,000 2,663,000 19,091,000 2,366,000 43,241,000 -1,121,000 -10,851,000 3,029,000 56,972,000 13,115,000 9,664,000 -2,456,000 15,827,000                                              
          supplemental disclosure for cash flow information:
                                                                                          
          cash paid for interest, net of amounts capitalized
        7,824,000   4,966,000 8,895,000   8,209,000 7,946,000    4,293,000 7,449,000 2,628,000 5,763,000 5,637,000 3,783,000 1,969,000 1,970,000 1,983,000 1,851,000 1,539,000 1,693,000 1,848,000 2,465,000 690,000 2,488,000 449,000 2,522,000 584,000 2,726,000 453,000 1,562,000 100,000                                                
          cash paid for income taxes, net of refunds received
        -6,065,000                                                                                  
          supplemental non-cash investing and financing activities:
                                                                                          
          accrued consideration for acquired product rights and intangible assets
        1,085,000                                                                                  
          property and equipment purchased and included in accounts payable
        784,000   -734,000 1,022,000   396,000 1,222,000    729,000 248,000 -575,000 526,000 253,000 124,000 -91,000 -99,000 218,000 -51,000 62,000 23,000 138,000 244,000 346,000 -37,000 170,000 411,000 -123,000 197,000 36,000 131,000 245,000 31,000 78,000 145,000 57,000 -40,000 85,000                                          
          unrealized gain on investment in equity securities
         -273,000    1,991,000 -1,355,000 2,712,000 -9,655,000                                                                          
          loss on disposal of assets
         87,000                                                                                 
          loss on extinguishment of debt
                                                                                          
          amortization of inventory step up
             10,375,000                                                                             
          asset impairment charges
                    -1,000                                                                    
          changes in operating assets and liabilities, net of acquisitions:
                                                                                          
          acquisition of alimera, net of cash acquired
             -8,201,000                                                                             
          proceeds from the sale of building
             13,514,000                                                                          
          proceeds from convertible notes
                                                                                         
          proceeds from term loan
                                                                                         
          purchase of capped call transaction
                                                                                         
          proceeds from public offering
                                                                                          
          payments on contingent consideration
            -12,500,000                                                                          
          debt issuance costs
             -1,977,000                                                                             
          repayment on borrowings under credit agreement
                                                                                         
          payment of accrued licensor payment
                                                                                          
          cash and cash equivalents, beginning of year
                                                                                          
          cash, cash equivalents and restricted cash, end of year
                                                                                          
          loss on debt extinguishment
                                                                                          
          payment of accrued licensor payments
                                                                                          
          gain on sale of building
             -5,347,000                                                                          
          cash paid for income taxes
           16,188,000 285,000   16,352,000 852,000    2,741,000 132,000 32,000   2,011,000 8,248,000 112,000 106,000 4,355,000 428,000 95,000 140,000 1,170,000   2,507,000 995,000   5,293,000 2,611,000 9,878,000 4,000 3,690,000 3,641,000 563,000 1,643,000 2,587,000 1,218,000 3,421,000 6,029,000 10,000 77,000 60,000                                  
          income taxes payable
            7,439,000                                                                              
          principal payments on borrowings under term loan a
            -2,031,000                                                                              
          acquired in-process research and development
                            3,753,000                                                        
          gain on sale of andas
                                                                                        
          acquisition of novitium pharma llc, net of cash acquired
                                                                                        
          proceeds from the sale of long-lived assets
                                                                                        
          principal payments on borrowings under credit agreements
             -2,031,000                                                                             
          changes in operating assets and liabilities, net of acquisition:
                                                                                          
          prepaid income taxes
              -3,237,000                                                                            
          cash. cash equivalents, and restricted cash end of period
                                                                                          
          payments on borrowings under credit agreements
               -750,000 -750,000 -750,000 -750,000 -750,000 -750,000 -750,000 -750,000 -750,000 -750,000                                                                  
          cash and cash equivalents, end of period
               11,513,000 228,597,000     -8,050,000 -7,102,000 -13,525,000 81,911,000 85,046,000 -9,007,000 -811,000 30,073,000 -10,036,000 -9,801,000               11,210,000 1,141,000 -62,733,000 77,747,000 3,771,000 -15,818,000 1,168,000 165,563,000 133,987,000 -17,911,000 1,588,000 51,373,000 175,194 -1,665,121                                
          right-of-use assets obtained in exchange for lease obligations
                                                                                          
          prepaid expenses and other current assets
                1,353,000 -8,379,000 -2,085,000 -64,000 1,513,000 -3,415,000 1,054,000 1,700,000 -137,000 -1,294,000 219,000 823,000 379,000 -2,503,000 -241,000 -150,000 1,028,000 913,000 -1,714,000 846,000 358,000 627,000 -2,875,000 576,000 530,000 1,348,000 -2,201,000 861,000 -25,000 -24,000 1,369,000 -2,193,000 201,000 -312,000 -370,000                                        
          current income taxes payable
                3,238,000 7,565,000 4,687,000 -353,000 92,000 -49,000 -1,765,000 -31,000 1,685,000 -637,000 -655,000 -6,034,000 -247,000                        -3,772,000                                      
          changes in operating assets and liabilities, net of acquisition
                                                                                          
          acquisition of product rights, ipr&d, and other related assets
                   -4,325,000 -4,000 -4,000 -7,346,000 -229,000 -12,000 -12,000 -21,018,000 -39,000 -9,000 -4,048,000 -2,123,000 -56,007,000 329,000 -409,000                                                      
          proceeds from public offering, net of transaction expenses
                                                                                         
          payments on term loan and delayed draw term loan agreements
                         -2,828,000 -2,828,000 -2,829,000 -2,377,000 -2,377,000 -2,378,000                                                            
          borrowings under prior revolver agreement
                                                                                          
          repayment of prior credit facility
                                                                                          
          borrowings under the credit facility, net of issuance costs
                                                                                          
          proceeds from issuance of convertible preferred stock
                                                                                          
          net change in cash and cash equivalents
                     -8,050,000 -7,102,000 -13,525,000 -23,390,000 85,046,000 -9,007,000 -811,000 17,206,000 -10,036,000 -9,801,000                                                            
          cash and cash equivalents, end of year
                                                                                          
          net loss
                     -4,243,000 -8,600,000    -4,447,000                                  -2,290,649 -3,987,331 -6,121,815 -7,344,116 -10,264,477 -6,648,905 -12,733,692 -14,975,231 -17,250,676 -13,271,735 -11,589,711 -10,794,351 -10,540,419 -32,485,898 -6,370,557 -4,620,701 -4,050,612  -6,585,084 -6,048,067 -3,626,638  -1,693,044 -2,400,309 -1,817,018      
          adjustments to reconcile net loss to net cash and cash equivalents from operating activities:
                                                                                          
          ​
                                                                                          
          payments on revolver agreement
                                                                                        
          borrowings under the credit facility
                                                                                          
          proceeds from issuance of common stock in public offering
                                                                                          
          cash paid for costs of share issuances
                                                                                          
          payments of debt issuance costs
                         -13,706,000 -121,000                                                                
          cash and cash equivalents, beginning of period
                     105,301,000 12,867,000               154,684,000 169,037,000 11,105,000 -28                                
          fair value of contingent consideration in a business combination
                                                                                          
          fair value of equity issued as consideration in a business combination
                                                                                          
          acquisition of product rights included in accounts payable
                                                                                         
          debt issuance costs in accrued expenses
                           -34,000 115,000                                                              
          net cash and cash equivalents from by financing activities
                        -2,270,000                                                                  
          acquisition of product rights, ipr&d, and other related assets included in returned goods reserve and derivatives and other non-current liabilities
                             -8,000                                                             
          asset impairment charge
                             341,000                                                             
          borrowings under delayed draw term loan agreement
                                                                                          
          borrowings under revolver agreement
                           15,000,000                                                          
          convertible preferred stock dividends paid
                                                                                          
          repayment of convertible notes
                                                                                          
          acquisition of product rights, ipr&d, and other related assets included in returned goods reserve and accrued liabilities
                            388,000                                                              
          loss on repurchase of convertible notes
                                                                                          
          current income taxes
                             5,527,000 -9,907,000 -6,937,000 16,299,000 -262,000 2,628,000 -6,895,000 -1,569,000 4,704,000 2,052,000 -1,672,000 1,100,000 890,000 1,939,000 -7,647,000 1,258,000 3,327,000 -779,000 1,000,000 -23,000 -155,000 50,000                                        
          acquisition of wellspring pharma services inc., net of cash acquired
                                                                                          
          payment of debt issuance and convertible debt repurchase costs
                                                                                          
          unwinding of portion of call option overlay
                                                                                          
          non-cash interest relating to convertible notes and loan cost amortization
                               523,000 182,000 1,345,000 1,913,000 1,893,000 1,873,000 2,073,000 2,155,000 2,130,000 2,107,000 1,943,000 1,933,000 1,908,000 1,882,000 1,860,000 1,939,000 1,757,000 1,725,000 1,696,000 1,747,000 1,705,000 1,683,000                                      
          adjustments to reconcile net loss to net cash and cash equivalents provided by operating activities:
                                                                                          
          payments on term loan agreement
                                -902,000 -902,000 -903,000 -902,000 -938,000 -937,000 -938,000                                                  
          proceeds from stock option exercises
                                281,000  133,000 2,303,000 2,416,000 161,000 206,000 1,100,000 1,511,000 162,000 60,000 106,000 25,000 208,000 858,000 360,000 144,000 161,000 414,000 235,000 9,000 42,000 34,000 743,000                                  
          change in cash, cash equivalents, and restricted cash
                                -41,945,000  19,091,000 2,366,000 -4,788,000  -10,851,000 3,029,000 20,822,000  9,664,000 -2,456,000 -16,540,000                                              
          acquisition of product rights, ipr&d, and other related assets included in accounts payable or accrued expenses
                                1,940,000                                                          
          intangible asset impairment charge
                                                                                          
          borrowings under term loan agreement
                                                                                          
          treasury stock purchases for restricted stock vestings
                                 -723,000 -308,000 -409,000 -250,000                                                  
          net cash and cash equivalents provided/(used in) by financing activities
                                                                                          
          reconciliation of cash, cash equivalents, and restricted cash, beginning of period cash and cash equivalents
                                                                                          
          reconciliation of cash, cash equivalents, and restricted cash, end of period cash and cash equivalents
                                                                                          
          acquisition of marketing and distribution rights included in accounts payable
                                                                                          
          acquired product rights and in-process research and development
                                                                                          
          payment of debt issuance costs
                                      -153,000                                                
          acquisition of product rights and other related assets
                                    -18,510,000     -46,668,000 -50,956,000 -60,312,000 -84,182,000 -26,000,000 -4,500,000                                     
          acquisiton of wellspring pharma services inc., net of cash acquired
                                                                                          
          excess tax benefit from share-based compensation awards
                                             310,000 288,000 18,000 1,000 126,000 187,000 38,000 9,000 352,000 424,000 -99,000 107,000                                  
          repurchase of common stock under the stock repurchase program
                                                                                        
          repurchase of convertible notes
                                                                                          
          net cash and cash equivalents (used in)/provided by financing activities
                                                                                          
          accrued royalties related to asset purchase
                                                                                        
          accrued compensation and related expenses
                                      702,000 -85,000 -811,000 297,000 782,000 92,000 -496,000 205,000 355,000 349,000 -466,000 169,000 175,000 331,000 -835,000                                      
          accrued expenses and other
                                      1,024,000 -749,000 1,069,000 -1,170,000 1,801,000 -1,148,000 1,161,000                                              
          net borrowings under line of credit agreement
                                          -5,000,000 30,000,000                                              
          adjustments to reconcile net income to net cash and cash equivalents provided by operating activities:
                                                                                          
          treasury stock purchases for restricted stock vestings and forfeitures
                                                                                       
          adjustments to reconcile net loss to net cash and cash equivalents
                                                                                          
          provided by operating activities:
                                                                                          
          changes in restricted cash
                                             -1,000                                            
          net proceeds from equity offering
                                                     -14,000 46,694,000                                  
          net proceeds from convertible debt offering
                                                                                          
          purchase of call option overlay
                                                                                          
          proceeds from warrant exercise
                                                                                          
          change in cash and cash equivalents
                                             11,210,000 1,141,000 -62,733,000 -76,937,000 3,771,000 -15,818,000 1,168,000 -3,474,000 133,987,000 -17,911,000 1,588,000 40,268,000 175,222 -1,665,121                                
          accrued medicaid rebates
                                              -58,000 3,085,000 -1,207,000 203,000 2,537,000 -186,000 -187,000                                      
          accrued expenses, returned goods reserve, and other
                                              786,000 -636,000 3,955,000  1,245,000 -825,000 1,000,000                                      
          cash paid for interest
                                                2,157,000       388                               
          repurchase of common stock
                                                -2,500,000                                          
          accrued royalties assumed in asset purchase
                                                1,199,000                                          
          loss on disposal of property and equipment
                                                                                         
          non-cash compensation relating to business combination
                                                         -524                                
          changes in operating assets and liabilities, net of those acquired in business combination:
                                                                                          
          accrued expenses, returned goods reserve and other
                                                                                          
          net cash and cash equivalents from continuing operations
                                                     10,741,000    -2,758,436 -1,546,952                                
          net cash from discontinued operation
                                                         -106,184 -84,440                                
          cash acquired in business combination
                                                         558                                
          release of restricted cash
                                                                                          
          repayment of line of credit
                                                                                          
          treasury stock purchases
                                                         -438                                
          issuance of common stock in connection with business combination
                                                                                          
          cancellation of series d, series c, series b, and series a preferred stock
                                                                                          
          acquired non-cash net assets
                                                                                          
          preferred stock dividends accrued
                                                                                          
          contingent payable for asset purchase
                                                                                          
          property and equipment purchased on credit
                                                  59,000 -55,000 105,000                                      
          prepaid expenses
                                                    437,000 -539,000 -106,000 73,000 14,000 143 -328,831                                
          non-cash interest relating to equity-linked securities and loan cost amortization
                                                                                          
          accrued expenses, returned goods reserve and deferred revenue
                                                      2,989,000 197,000 -209,000 407,858 216,528                                
          net cash and cash equivalents from discontinued operation
                                                                                          
          borrowings under line of credit
                                                                                          
          proceeds from warrant exercises
                                                      180,000                                  
          acquisition of intangible assets
                                                       -12,517,000                                  
          adjustments to reconcile net loss to net cash and cash equivalents used in operating activities:
                                                                                          
          accrued compensation
                                                                                          
          (repayments)/borrowings under line of credit
                                                         307                                
          issuance of common and preferred stock upon cashless warrant exercise
                                                                                          
          issuance of preferred stock upon convertible debt conversion
                                                                                          
          net loss from continuing operations
                                                          1,040,706                                
          used in operating activities:
                                                                                          
          non-cash interest relating to convertible debt and loan cost amortization
                                                                                         
          acquisition of property and equipment, net of disposals
                                                          -33,729                                
          issuance of common stock in business combination
                                                                                         
          cancellation of series d, series c, series b, series a, and common stock
                                                                                          
          acquired intangibles
                                                                                         
          acquired goodwill
                                                                                         
          acquired restricted cash
                                                                                         
          other acquired tangible assets
                                                                                         
          assumed liabilities
                                                                                         
          preferred stock dividends
                                                                                         
          exchange of series d, series c, series b, series a, and common stock
                                                                                          
          adjustments to reconcile net loss to net cash (used in) operating activities
                                                                                          
          loss on disposal of fixed assets
                                                              117,362 432   2,099                      
          gain on sale of intellectual property
                                                                                          
          employee and director stock-based compensation
                                                            145,794    313,027    300,385                      
          convertible note fair value adjustment
                                                            285,329 290,671 843,412 -15,953 3,210,338 -1,905,573 -463,000 1,753,000 639,000                      
          changes in other assets and liabilities affecting cash flows from operations
                                                                                          
          accounts payable and accrued liabilities
                                                                 -2,858,956 -190,360 -1,227,452 4,410,871 -40,967 404,879 477,124 2,301,042 -1,675,443    -615,621 694,770 701,068 1,409,626 2,051,657 -228,943 324,297 -1,697,155      
          net cash from operating activities
                                                                               -4,684,434 -2,460,126 1,296,420 -2,072,384 -2,039,260 3,555,216      
          capital expenditures
                                                                                    
          free cash flows
                                                                               -4,684,434 -2,460,126 1,296,420 -2,072,384 -2,039,260 3,555,216      
          funding of restricted cash
                                                                                          
          proceeds from sale of intellectual property
                                                            1,000,000                              
          purchase of fixed assets
                                                                                          
          purchase of investment
                                                                                          
          net cash from investing activities
                                                                         -12,309 -741 2,873,660 8,578,479 962,828 1,869,918 -82,699 -11,074,771 -49,910 -53,757 -60,988 6,107,779 -5,567,479 2,609,597 1,805,759 1,232,967 
          net (decrease) in cash and cash equivalents
                                                                                          
          cash and cash equivalents at beginning of period
                                                            34,794,341 57,225,234 38,155,251 29,858,465 11,760,920             
          cash and cash equivalents at end of period
                                                            29,388,772 -3,254,754 -4,367,950 -7,056,687 49,473,732 -12,374,965 32,474,193 -14,223,015 51,349,021 2,629,234 -10,856,095 5,219,111 41,163,001 16,689,207 7,183,435 -4,176,523 10,162,346 6,060,222 -4,624,880 -2,780,546 13,106,123 -9,753,615 -1,979,604 16,091,426 11,290,742 7,287,678 232,569 63,416 70,189 56,501 
          supplemental schedule of cash flow information
                                                                                          
          noncash financing activities
                                                                                          
          shares issued for convertible senior notes and accrued interest
                                                             3,748,518 10,132,534                          
          stock warrant expense - noncash
                                                                 24,221 28,205 102,144 50,410 8,334 19,759 37,436  3,209 19,868 11,657 -9,366 50,037 28,649 34,964          
          loss on disposal or impairment of equipment
                                                                                          
          investment impairment charge
                                                                                          
          other non-cash items
                                                                                          
          changes in assets and liabilities affecting cash flows from operations
                                                                                          
          purchase of investments
                                                                                          
          proceeds from sale of fixed assets
                                                                     825                     
          fractional share payout
                                                                                          
          cash paid for convertible note repayment
                                                                                          
          proceeds from common stock option exercises
                                                                                          
          proceeds from common stock warrant exercises
                                                                                          
          proceeds from issuance of common stock by underwritten offering
                                                                                          
          proceeds from issuance of common stock by registered direct offering
                                                                                          
          net cash from financing activities
                                                             -7,933    -1,375,448 45,160,113 -13,281 23,888,627 16,865,766 -264 14,115,849 17,473,307 22,838,146    -60,343 345,750   24,736 142,690 18,184,443 142,662 -1 7,146,937 -6,323 243,675  
          net increase in cash and cash equivalents
                                                                               -2,780,546 -2,542,825 -9,753,615 -1,979,604 16,091,426 3,636,890 7,287,678     
          interest paid, including acquired accrued interest
                                                                                          
          noncash investing and financing activities:
                                                                                          
          investment - non-cash
                                                                                          
          purchase of fixed assets on account, non-cash investing activity
                                                                 -37,611 20,630                        
          adjustments to reconcile net loss to net cash from operations
                                                                                          
          employee & director stock-based compensation
                                                              270,002    305,162    268,154 278,665 204,971  305,199 305,199 336,119  305,188 301,111 258,775          
          prepaid expenses, deposits and other assets
                                                              37,308    69,605    -212,610                    
          proceeds from warrants exercised
                                                                                          
          proceeds from issuance of common stock by underwritten public offering
                                                                                          
          proceeds from issuance of common stock by registered direct offerings
                                                                  17,415 -29,672 23,888,627                      
          interest paid
                                                                                        
          noncash investing and financing activities
                                                                                          
          unpaid costs associated with registered direct offering
                                                                                          
          unpaid costs associated with underwritten public offering
                                                                                          
          adjustments to reconcile net loss to net cash (used in) operations
                                                                                          
          net (decrease) cash and cash equivalents
                                                                                          
          net increase cash and cash equivalents
                                                                    13,193,770  -10,856,095 5,219,111 11,304,536                  
          excess consideration paid over fair value
                                                                                          
          loss on disposal of equipment
                                                                                 -2,450        
          redemption of short term investments
                                                                         -11,648 3,037,982 8,878,288 1,101,354   -1   6,094,908 2,324,216 2,683,141 1,902,458 1,350,001 
          cash paid for transaction related costs
                                                                                          
          cash received in transaction
                                                                                          
          liabilities acquired through cell genesys transaction
                                                                                          
          shares issued for cell genesys transaction
                                                                                          
          investment aquired through cell genesys transaction
                                                                                          
          other assets acquired in cell genesys transaction
                                                                                          
          loss on write-down of fixed assets
                                                                                          
          investment impairment loss - noncash
                                                                                          
          proceeds from common stock option exercised
                                                                                          
          deferred revenue
                                                                               -4,545 -4,546 -9,091 -9,091 -6,818 -34,091     -34,091 
          credit equity financing facility
                                                                                          
          adjustments to reconcile net loss to net cash used in operating activities:
                                                                                          
          mark-to-market of convertible senior notes
                                                                      -103,000 381,916 1,409,000                  
          acquisition related costs
                                                                                          
          other noncash charges
                                                                                          
          gain on disposal of fixed assets
                                                                                          
          changes in other assets and liabilities affecting cash flows from operations:
                                                                                          
          due to licensor - antares
                                                                          -8,329   730 -309 -1,960 5,869          
          purchase of short term investments
                                                                               -15,991 -68,074 -11,053,342 -49,104 -47,545 -60,988      
          purchase of capital assets
                                                                               -114,091 -14,625          
          cash paid for acquisition related costs
                                                                                          
          proceeds from sale or conversion of shares
                                                                      -264 14,115,849 17,473,307 12,134    -60,343 345,750     18,184,443 142,662 -1 7,146,937 -6,323 243,675  
          supplementary information
                                                                                          
          other information:
                                                                                          
          accrued liabilities for acquisition related costs, noncash
                                                                                          
          adjustments to reconcile net loss to net cash from operating activities:
                                                                                          
          accrued liabilities for deferred acquisition costs, noncash
                                                                                          
          adjustments to reconcile net loss to net cash from operating activities
                                                                                          
          stock warrant expense — noncash
                                                                                          
          other non-cash charges
                                                                                          
          fair value adjustment
                                                                                          
          matc license revenue — noncash
                                                                                          
          provision for contingencies
                                                                                    -137,647      
          due to licensor — antares
                                                                                          
          purchase of capital assets on account, non-cash investing activity
                                                                             -102,421             
          investment in matc — noncash
                                                                                          
          impairment of short term investments
                                                                                         
          (gain) on disposal of equipment
                                                                                          
          unrealized gain on available-for-sale securities, non-cash
                                                                                          
          cash flows provided by investing activities
                                                                                          
          unrealized loss on available-for-sale securities, noncash
                                                                                602,000          
          adjustments to reconcile net income to net cash from operating activities
                                                                                          
          matc license revenue - noncash
                                                                                          
          investment in matc - noncash
                                                                                          
          income tax paid
                                                                                  75,000      
          adjustments to reconcile net loss to
                                                                                          
          (gain) loss on disposal of equipment
                                                                                          
          changes in other assets and liabilities
                                                                                          
          affecting cash flows from operations
                                                                                          
          cash flows provided by financing activities
                                                                                          
          at beginning of period
                                                                               15,648,948  7,653,852  310,643  
          see accompanying notes to the condensed financial statements.
                                                                                          
          stock warrant expense-noncash
                                                                                          
          matc license revenue-noncash
                                                                                          
          due to licensor-antares
                                                                                          
          supplemental schedule of noncash investing cash flow information
                                                                                          
          investment in matc
                                                                                          
          employee & director compensation - noncash
                                                                                  147,341 142,905 220,798 52,407 49,203 116,209 859,013 87,875 
          consultant compensation - noncash
                                                                                          
          prepaid expenses, deposits and other sundry assets
                                                                                  -200,394    -62,615    
          accrual for contingencies
                                                                                  -137,647    -201,765 140,000  
          purchases of capital assets
                                                                                  -806        
          proceeds from sale of shares and exercise of options
                                                                                          
          and warrants
                                                                                          
          see accompanying notes to the financial statements.
                                                                                          
          prepaid expenses and other sundry assets
                                                                                    -8,405    17,500 8,335 
          amortization of deferred unearned compensation
                                                                                          
          repurchase of licensing rights
                                                                                          
          purchased in-process research and development
                                                                                          
          due from sbi
                                                                                          
          issuance of convertible debenture
                                                                                          
          supplemental schedule of
                                                                                          
          cash flow information
                                                                                          
          acquisition of sbi
                                                                                          
          other net liabilities assumed
                                                                                          
          less: subordinate voting shares issued therefor
                                                                                          
          -
                                                                                          
          significant non-cash transactions
                                                                                          
          fair value of common stock warrants issued in connection
                                                                                          
          with the sale of capital stock
                                                                                          
          due from licensee
                                                                                          
          due to licensor
                                                                                          
          net cash used in operating activities
                                                                                          
          net cash provided by financing activities
                                                                                          
          fair value of common stock warrants issued in connection with the sale of capital stock
                                                                                          
          accounts payable and accrued expenses
                                                                                          
          proceeds from sales or conversion of shares
                                                                                          
          net increase in cash
                                                                                          
          and cash equivalents
                                                                                          
          less: common stock issued therefor
                                                                                          
          cash flows used in operating activities
                                                                                          
          benefit from contingencies