7Baggers

Verastem, Inc
(NASDAQ:VSTM) 

VSTM stock logo

Verastem, Inc., a development-stage biopharmaceutical company, focusing on developing and commercializing medicines to enhance the life of cancer patients. Its product in development include VS-6766, a dual rapidly accelerated fibrosarcoma (RAF)/mitogen-activated protein kinase (MEK) inhibitor that ...

Founded: 2010
Full Time Employees: 135
Sector: Healthcare
Industry: Biotechnology
PharmaceuticalsOncology
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At a glance:
Bull Thesis:
Bear Thesis:
Main Competitors:
Moat:
Income Statements:
Quarterly
Annual
    Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2011-12-31 
                                                  
      revenue:
    		                                              
      product revenue
    		18,671,000 17,535,000 11,242,000 2,137,000                  134,000 5,829,000 4,235,000 5,034,000 3,617,000 4,032,000 3,019,000 1,671,000 1,210,000 508,000                
      total revenue
    		18,671,000 17,535,000 11,242,000 2,137,000    10,000,000         2,596,000 545,000 2,000 500,000 1,006,000 506,000 78,647,000 4,307,000 5,056,000 3,616,000 9,032,000 3,136,000 1,671,000 1,210,000 15,508,000 10,000,000               
      yoy
    		  NaN% -78.63%   NaN% NaN%   NaN% NaN% NaN%  NaN% NaN% 158.05% 7.71% -100.00% -88.39% -80.10% -86.01% 770.76% 37.34% 202.57% 198.84% -41.76% -68.64%                   
      qoq
    		6.48% 55.98% 426.06%    NaN%    NaN% NaN%   NaN% NaN% 376.33% 27150.00% -99.60% -50.30% 98.81% -99.36% 1726.03% -14.81% 39.82% -59.96% 188.01% 87.67% 38.10% -92.20% 55.08%                
      operating expenses:
    		                                              
      cost of sales - product
    		2,772,000 2,612,000 1,670,000 318,000                  12,000 866,000 392,000 495,000 332,000 371,000 377,000                   
      cost of sales - intangible amortization
    		279,000 280,000 290,000 128,000                   8,000 393,000 392,000 392,000 392,000 392,000                   
      research and development
    		38,218,000 31,674,000 28,989,000 24,786,000 29,152,000 20,811,000 24,754,000 18,062,000 17,707,000 22,502,000 13,946,000 12,893,000 12,015,000 10,740,000 11,288,000 14,888,000 13,642,000 11,396,000 9,325,000 9,730,000 8,896,000 10,153,000 10,955,000 9,344,000 10,924,000 12,456,000 12,219,000 11,346,000 9,758,000 8,762,000 11,571,000 12,381,000 10,934,000 11,253,000 17,743,000 9,042,000 8,385,000 6,892,000 4,216,000 4,492,000 4,179,000 7,688,000 11,304,000 11,045,000 10,528,000  
      selling, general and administrative
    		22,299,000 24,444,000 21,008,000 20,669,000 15,022,000 10,779,000 12,276,000 10,215,000 10,352,000 8,637,000 7,363,000 7,399,000 7,329,000 6,106,000 6,421,000 6,514,000 5,934,000 5,660,000 5,523,000 6,714,000 6,218,000 7,095,000 20,614,000 15,442,000 19,604,000 23,728,000 22,153,000 29,298,000 26,033,000 26,199,000 25,426,000                
      total operating expenses
    		63,568,000 59,010,000 51,957,000 45,901,000 44,174,000 31,590,000 37,030,000 28,277,000 28,059,000 31,139,000 21,309,000 20,292,000 19,344,000 16,846,000 17,709,000 21,402,000 19,576,000 17,056,000 14,848,000 16,444,000 15,114,000 17,260,000 63,630,000 25,571,000 31,415,000 36,908,000 35,135,000 41,413,000 36,341,000 35,469,000 37,077,000 28,194,000 20,761,000 18,052,000 23,137,000 13,467,000 13,148,000 11,800,000 8,059,000 8,709,000 8,434,000 11,961,000 15,534,000 15,462,000 15,242,000  
      income from operations
    		-44,897,000 -41,475,000 -40,715,000 -43,764,000 -44,174,000 -31,590,000 -37,030,000 -18,277,000 -28,059,000 -31,139,000 -21,309,000 -20,292,000 -19,344,000 -16,846,000 -17,709,000 -21,402,000 -16,980,000 -16,511,000 -14,846,000 -15,944,000 -14,108,000 -16,754,000 15,017,000 -21,264,000 -26,359,000 -33,292,000 -26,103,000 -38,277,000 -34,670,000 -34,259,000 -21,569,000 -18,194,000 -20,761,000 -18,052,000 -23,137,000 -13,467,000 -13,148,000 -11,800,000 -8,059,000 -8,709,000 -8,434,000      
      yoy
    		1.64% 31.29% 9.95% 139.45% 57.43% 1.45% 73.78% -9.93% 45.05% 84.85% 20.33% -5.19% 13.92% 2.03% 19.28% 34.23% 20.36% -1.45% -198.86% -25.02% -46.48% -49.68% -157.53% -44.45% -23.97% -2.82% 21.02% 110.38% 67.00% 89.78% -6.78% 35.10% 57.90% 52.98% 187.10% 54.63% 55.89%          
      qoq
    		8.25% 1.87% -6.97% -0.93% 39.84% -14.69% 102.60% -34.86% -9.89% 46.13% 5.01% 4.90% 14.83% -4.87% -17.26% 26.04% 2.84% 11.22% -6.89% 13.01% -15.79% -211.57% -170.62% -19.33% -20.82% 27.54% -31.81% 10.40% 1.20% 58.83% 18.55% -12.36% 15.01% -21.98% 71.81% 2.43% 11.42% 46.42% -7.46% 3.26%       
      operating margin %
    		-240.46% -236.53% -362.17% -2047.92% -Infinity% -Infinity% NaN% -182.77% -Infinity% -Infinity% NaN% NaN% NaN% -Infinity% NaN% NaN% -654.08% -3029.54% -742300.00% -3188.80% -1402.39% -3311.07% 19.09% -493.71% -521.34% -920.69% -289.01% -1220.57% -2074.81% -2831.32% -139.08% -181.94% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% NaN% NaN% NaN% NaN%  
      other expense
    		-61,000 -17,000 -37,000 -110,000 -40,000 -32,750 -77,000 -24,000 -30,000             -328,250   -1,313,000                      
      interest income
    		1,297,000 1,104,000 1,182,000 822,000 960,000 968,000 831,000 983,000 1,367,000 1,869,000 2,247,000 1,122,000 976,000 769,000 316,000 84,000 46,000 40,000 40,000 49,000 52,000 18,000 19,000 122,000 356,000 611,000 1,005,000 1,268,000 1,497,000 1,306,000 763,000 343,000 191,000 145,000 121,000 140,000 155,000 145,000 137,000 140,000 140,000 98,000 89,000 85,000 62,000  
      interest expense
    		-382,000 -415,000 -319,000 -212,000 -192,000 -1,146,000 -1,148,000 -1,138,000 -1,130,000 -1,120,000 -1,129,000 -1,121,000 -769,000 -724,000 -717,000 -640,000 -56,000 -10,000 -7,980,000 -1,007,000 -975,000 -1,354,000 -1,898,000 -1,868,000 -10,674,000 -5,452,000 -5,041,000 -5,185,000 -4,929,000 -3,952,000 -862,000 -516,000 -480,000 -328,000 -110,000 -109,000 -12,000          
      loss on debt extinguishment
    		    -1,826,000                                          
      change in fair value of warrant liability
    		9,323,000 10,485,000 -55,881,000 20,320,000 -2,416,000 -32,606,000 13,457,000                                        
      change in fair value of notes
    		-1,871,000 -2,598,000 -2,748,000 -2,990,000 -4,415,000                                          
      net income
    		-36,591,000 -32,916,000 -98,518,000 -25,934,000 -52,103,000 -64,551,000 -23,967,000 -8,256,000 -33,863,000 -27,368,000 -20,004,000 -24,281,000 -15,714,000 -16,808,000 -18,090,000 -21,952,000 -16,962,000 -16,481,000 -22,786,000 -16,902,000 -15,031,000 -19,864,000 13,138,000 -23,010,000 -37,990,000 -38,774,000 -30,139,000 -42,194,000 -38,102,000 -11,349,000 -21,668,000 -18,367,000 -21,050,000 -12,391,750 -23,126,000 -13,436,000 -13,005,000 -11,655,000 -7,922,000 -8,569,000 -8,294,000 -11,863,000 -15,445,000 -15,377,000 -15,180,000  
      yoy
    		-29.77% -49.01% 311.06% 214.12% 53.86% 135.86% 19.81% -66.00% 115.50% 62.83% 10.58% 10.61% -7.36% 1.98% -20.61% 29.88% 12.85% -17.03% -273.44% -26.54% -60.43% -48.77% -143.59% -45.47% -0.29% 241.65% 39.09% 129.73% 81.01% -8.41% -6.30% 36.70% 61.86% 6.32% 191.92% 56.80% 56.80% -1.75% -48.71% -44.27% -45.36%      
      qoq
    		11.16% -66.59% 279.88% -50.23% -19.28% 169.33% 190.30% -75.62% 23.73% 36.81% -17.61% 54.52% -6.51% -7.09% -17.59% 29.42% 2.92% -27.67% 34.81% 12.45% -24.33% -251.20% -157.10% -39.43% -2.02% 28.65% -28.57% 10.74% 235.73% -47.62% 17.97% -12.75% 69.87% -46.42% 72.12% 3.31% 11.58% 47.12% -7.55% 3.32% -30.09% -23.19% 0.44% 1.30%   
      net income margin %
    		-195.98% -187.72% -876.34% -1213.57% -Infinity% -Infinity% NaN% -82.56% -Infinity% -Infinity% NaN% NaN% NaN% -Infinity% NaN% NaN% -653.39% -3024.04% -1139300.00% -3380.40% -1494.14% -3925.69% 16.71% -534.25% -751.38% -1072.29% -333.69% -1345.47% -2280.19% -937.93% -139.72% -183.67% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity%  
      net income per share
    		-0.37 -0.29 -1.35 -0.39 -0.96 -1.55 -0.6 -0.31 -1.26 -1.03 -0.75 -1.37 -0.08 -0.08 -0.09 -0.12 -0.09 -0.1 -0.13 -0.1 -0.09 -0.12 0.08 -0.14 -0.35 -0.51 -0.41 -0.57 -0.52 -0.13 -0.29 -0.3 -0.41 -0.43 -0.61 -0.36 -0.35 -0.32 -0.21 -0.23 -0.22 -0.32 -0.42 -0.42 -0.46  
      weighted-average common shares outstanding used in computing net loss per share—basic
    		98,292                                              
      weighted-average common shares outstanding used in computing net loss per share—diluted
    		99,148                                              
      unrealized gain on available-for-sale securities
    		-7       4 -17 -36 48 -5 6 39 91 -17    5  53  -9  -13 -59 -24 -17 125  4 2 -6.75 7 -17 -17   -58       
      change in fair value of notes attributable to instrument specific credit risk
    		3,396 7,774 2,745 1,349 6,639                                          
      comprehensive loss
    		-33,202 -25,142 -95,773 -24,585 -45,464 -64,551 -23,967 -8,252 -33,880 -27,404 -19,956 -24,286 -15,708 -16,769 -17,999 -21,969 -17,109   -16,897 -15,050 -19,811 13,138 -23,019 -37,995 -38,787 -30,198 -42,218 -38,119 -11,224 -21,670 -18,363 -21,048 -12,398.5 -23,119 -13,453 -13,022 -6,192 -7,939 -8,627 -8,202 -11,864 -15,433 -15,384 -15,152  
      sale of copiktra license and related assets
    		       10,000,000         2,596,000 545,000  52,000 850,000  70,000,000                        
      change in fair value of preferred stock tranche liability
    		       10,200,000 -6,011,000 3,071,000 200,000 -3,950,000 3,430,000                                  
      weighted-average common shares outstanding used in computing net loss per share—basic and diluted
    		 69,309 73,157  54,173 35,713 40,258 26,861 26,832 22,054 26,790 17,732 200,679 193,654 197,151 186,463 186,264          74,228 73,877 73,854                  
      weighted-average common shares outstanding used in computing net loss per share:
    		                                              
      other income
    		         -49,000 -13,000 -40,000 -7,000 -7,000 20,000 6,000 28,000                              
      transition services revenue
    		                  2,000 448,000 156,000                          
      unrealized loss on available-for-sale securities
    		                -147    -19                          
      license and collaboration revenue
    		                      2,818,000 72,000 22,000 -1,000 5,000,000 117,000                   
      cost of sales - sale of copiktra license and related assets
    		                      31,187,000                        
      weighted-average common shares outstanding used in computing:
    		                                              
      unrealized (loss) on available-for-sale securities
    		                 -6.5 -12                            
      comprehensive income
    		                 -13,686.25 -22,798                            
      weighted-average common shares outstanding used in computing net loss per share - basic and diluted
    		                 174,406  171,985 171,586   165,395 108,153                      
      ​
    		                                              
      costs of revenues, excluding amortization of acquired intangible assets
    		                            158,000 116,000 49,000                
      amortization of acquired intangible assets
    		                            392,000 392,000 31,000                
      license revenue
    		                              15,000,000 10,000,000               
      weighted-average number of common shares used in net loss per share—basic and diluted
    		                              73,644 61,256 50,835  37,630 36,992 36,992  36,992 36,992 36,975 35,932 36,898 36,522 33,323  
      general and administrative
    		                               15,813,000 9,827,000 6,799,000 5,394,000 4,425,000 4,763,000 4,908,000 3,843,000 4,217,000 4,255,000 4,273,000 4,230,000 4,417,000 4,714,000  
      unrealized gains on available-for-sale securities
    		                                     4.25 -17  92    28  
      unrealized gains (losses) on available-for-sale securities
    		                                         8.25 12    
    Balance Sheets:
    Quarterly
    Annual
      Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2011-12-31 
                                                    
        assets
      		                                              
        current assets:
      		                                              
        cash and cash equivalents
      		165,551,000 204,990,000 137,706,000 164,322,000 117,569,000 88,818,000 113,175,000 83,371,000 81,316,000 77,909,000 94,986,000 183,086,000 97,260,000 74,933,000 78,166,000 63,950,000 46,687,000 21,252,000 24,314,000 24,972,000 35,514,000 67,782,000 170,470,000 125,328,000 135,061,000 43,514,000 103,320,000 113,080,000 91,525,000 129,867,000 130,727,000 168,692,000 64,215,000 82,176,000 51,270,000 27,583,000 28,179,000 32,349,000 37,274,000 39,564,000 15,147,000 24,870,000 19,831,000 35,172,000 30,125,000 20,954,000 
        short-term investments
      		16,127,000        28,809,000 59,220,000 70,677,000  13,944,000 12,961,000 25,810,000 30,357,000 59,591,000 79,004,000 79,102,000 83,163,000 85,583,000 73,444,000    31,992,000 56,908,000 74,173,000 120,134,000 119,786,000 14,912,000   4,496,000 8,994,000 30,335,000 44,392,000 48,548,000 49,608,000 53,302,000 84,388,000 85,388,000 100,636,000 96,921,000 101,946,000 26,857,000 
        accounts receivable
      		10,158,000 8,813,000 6,716,000 2,076,000    10,000,000    2,000  31,000 74,000 131,000 2,644,000 516,000 105,000 476,000 1,125,000 239,000 5,685,000 1,500,000 3,326,000 2,524,000 2,203,000 1,389,000 558,000 306,000 10,562,000                
        inventory
      		2,287,000 1,833,000 1,794,000 1,168,000                    6,316,000 4,372,000 3,096,000 478,000 294,000 306,000 327,000 131,000                
        grant receivable
      		200,000 200,000 200,000 200,000 200,000 200,000 200,000 825,000 226,000                                      
        prepaid expenses and other current assets
      		8,581,000 7,577,000 7,640,000 6,507,000 6,930,000 5,943,000 7,287,000 5,450,000 7,323,000 6,553,000 8,822,000 6,875,000 7,689,000 4,945,000 4,709,000 3,437,000 4,517,000 4,968,000 5,236,000 6,149,000 5,456,000 3,473,000 3,033,000 6,558,000 5,887,000 3,835,000 4,049,000 3,410,000 4,073,000 2,973,000 2,397,000 1,745,000 1,815,000 1,115,000 940,000 1,835,000 1,434,000 398,000 431,000 667,000 1,002,000 585,000 714,000 651,000 2,801,000 130,000 
        total current assets
      		202,904,000 223,413,000 154,056,000 174,273,000 124,699,000 94,961,000 120,662,000 99,646,000 117,674,000 143,682,000 174,485,000 189,963,000 118,893,000 92,870,000 108,759,000 97,875,000 113,439,000 105,740,000 108,757,000 114,760,000 127,678,000 144,938,000 188,555,000 144,592,000 148,646,000 84,961,000 166,958,000 192,346,000 216,596,000 253,259,000 158,729,000 170,437,000 66,030,000 87,787,000 61,204,000 59,753,000 74,005,000 81,295,000 87,313,000 93,533,000 100,537,000 110,843,000 121,181,000 132,744,000 134,872,000 47,941,000 
        property and equipment
      		  20,000 21,000 22,000 32,000 39,000 46,000 52,000 37,000 35,000 40,000 62,000 92,000 121,000 151,000 180,000 210,000 240,000 270,000 335,000 416,000 497,000 791,000 866,000 947,000 1,041,000 1,149,000 1,256,000 1,369,000 1,210,000 1,270,000 1,003,000 861,000 989,000 1,127,000 1,271,000 1,417,000 1,569,000 1,728,000 1,865,000 2,048,000 2,282,000 2,456,000 2,645,000 709,000 
        right-of-use asset
      		2,793,000 491,000 730,000 963,000 1,188,000 1,405,000 625,000 816,000 997,000 1,171,000 1,336,000 1,494,000 1,645,000 1,789,000 1,927,000 2,058,000 2,183,000 2,302,000 2,416,000 2,524,000 2,628,000 2,726,000 2,820,000 2,909,000 2,995,000 3,077,000 3,146,000 3,225,000 3,303,000                  
        restricted cash
      		241,000    241,000 241,000  241,000 241,000 241,000 241,000 241,000 241,000 241,000 241,000 241,000 241,000 241,000 241,000 241,000 241,000 241,000 9,367,000 4,890,000 35,241,000 35,241,000     242,000 242,000 403,000 162,000 162,000 162,000 162,000 162,000 162,000 162,000 162,000 203,000 203,000 203,000 203,000 86,000 
        intangible assets
      		16,146,000 16,426,000 16,705,000 15,636,000                    19,223,000 19,616,000 20,008,000 20,400,000 20,793,000 21,185,000 21,577,000 21,969,000                
        other assets
      		5,724,000 6,112,000 5,341,000 5,371,000 5,548,000 4,899,000 5,052,000 4,998,000 4,575,000 4,587,000 56,000 20,000 36,000 58,000 47,000 84,000 105,000 169,000 223,000 103,000 21,000 33,000 23,000 401,000 790,000 812,000 1,055,000 1,028,000 1,025,000 1,031,000 1,005,000 969,000 975,000 981,000 784,000 797,000 811,000 755,000      293,000 282,000 1,307,000 
        total assets
      		227,808,000 246,442,000 176,852,000 196,264,000 131,698,000 101,538,000 126,378,000 105,747,000 123,539,000 149,718,000 176,153,000 191,758,000 120,877,000 95,050,000 111,095,000 100,409,000 116,148,000 108,662,000 111,877,000 123,890,000 136,901,000 154,349,000 217,770,000 198,532,000 208,154,000 145,046,000 192,600,000 218,541,000 243,365,000 277,236,000 183,155,000 172,918,000 68,411,000 89,791,000 63,139,000 61,839,000 76,249,000 83,629,000 89,044,000 95,423,000 102,564,000 113,094,000 123,666,000 135,696,000 142,003,000 59,037,000 
        liabilities, convertible preferred stock and stockholders’ equity
      		                                              
        current liabilities:
      		                                              
        accounts payable
      		9,602,000 12,448,000 9,888,000 8,047,000 7,199,000 4,026,000 4,438,000 6,678,000 7,449,000 7,184,000 5,118,000 4,553,000 4,903,000 4,901,000 5,359,000 1,706,000 2,896,000 2,302,000 641,000 1,395,000 2,453,000 1,875,000 4,681,000 2,241,000 7,233,000 9,655,000 8,842,000 11,538,000 8,593,000 10,253,000 11,249,000 8,514,000 7,267,000 9,186,000 7,363,000 6,825,000 8,809,000 4,095,000 1,962,000 2,149,000 2,595,000 3,942,000 3,646,000 2,999,000 3,951,000 2,273,000 
        accrued expenses, short-term
      		50,954,000 53,981,000 44,721,000 38,136,000                                           
        note payable
      		529,000  188,000 467,000 740,000  133,000 526,000 911,000  146,000 579,000 1,004,000                                  
        vendor financing arrangement, short-term
      		5,266,000 5,304,000 4,122,000 2,667,000 1,270,000                                          
        lease liability, short-term
      		494,000 535,000 793,000 1,044,000 1,019,000 995,000 780,000 1,022,000 981,000 941,000 902,000 865,000 829,000 794,000 761,000 728,000 696,000 667,000 638,000 610,000 583,000 558,000 533,000 508,000 485,000 420,000 379,000 294,000 203,000                  
        total current liabilities
      		66,845,000 72,268,000 59,712,000 50,361,000 35,619,000 30,973,000 37,374,000 30,347,000 26,725,000 26,380,000 23,812,000 20,787,000 22,359,000 21,663,000 21,873,000 20,092,000 16,886,000 18,590,000 13,536,000 12,744,000 11,844,000 17,093,000 37,678,000 28,784,000 25,728,000 29,890,000 30,510,000 31,204,000 28,624,000 37,077,000 53,441,000 22,132,000 14,845,000 17,128,000 19,618,000 11,066,000 13,233,000 10,991,000 6,220,000 5,925,000 6,124,000 10,109,000 10,864,000 9,837,000 9,461,000 3,146,000 
        non-current liabilities:
      		                                              
        long-term debt
      		73,120,000 76,330,000 78,124,000 74,274,000 71,476,000 40,724,000 30,647,000 35,390,000 40,123,000 40,086,000 39,911,000 39,739,000 39,574,000 24,526,000 24,399,000 24,276,000 24,157,000      26,397,000 30,899,000 35,276,000 35,067,000 34,882,000 34,673,000 24,814,000 19,506,000 21,535,000 23,520,000 14,913,000 14,828,000 2,335,000 2,293,000 2,249,000          
        vendor financing arrangement, long-term
      		3,750,000 5,000,000 6,250,000 6,263,000 2,019,000                                          
        lease liability, long-term
      		2,316,000    271,000 535,000   270,000 530,000 780,000 1,022,000 1,250,000 1,470,000 1,682,000 1,887,000 2,079,000 2,264,000 2,443,000 2,615,000 2,776,000 2,931,000 3,081,000 3,225,000 3,359,000 3,489,000 3,572,000 3,694,000 3,808,000                  
        warrant liability
      		 35,647,000 48,292,000 21,757,000 54,746,000 58,199,000 26,138,000                                        
        total liabilities
      		146,031,000 189,245,000 192,378,000 160,208,000 164,131,000 130,431,000 94,159,000 65,737,000 77,318,000 71,185,000 71,814,000 69,008,000 66,693,000 47,659,000 48,222,000 46,517,000 43,377,000 21,103,000 16,222,000 35,685,000 34,292,000 39,075,000 87,997,000 84,159,000 85,171,000 137,872,000 171,083,000 169,234,000 154,905,000 152,937,000 75,542,000 46,051,000 29,859,000 32,107,000 22,154,000 13,607,000 15,777,000          
        stockholders’ equity:
      		                                              
        preferred stock, 0.0001 par value...
      		                                              
        common stock, 0.0001 par value...
      		9,000 8,000 7,000 6,000 5,000 4,000 4,000 3,000 3,000 3,000 3,000 3,000 20,000 20,000 21,000 19,000 19,000 19,000 18,000 17,000 17,000 17,000 17,000 17,000 16,000 8,000 7,000 7,000 7,000 7,000 7,000 7,000 5,000 5,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 1,000 
        additional paid-in capital
      		1,274,739,000 1,216,958,000 1,114,004,000 1,064,324,000 968,553,000 926,630,000 902,032,000 885,857,000 883,816,000 882,248,000 880,650,000 879,105,000 786,236,000 784,894,000 783,606,000 756,628,000 753,538,000 751,217,000 742,840,000 712,593,000 710,100,000 707,715,000 702,403,000 700,141,000 685,733,000 531,937,000 507,494,000 505,086,000 502,021,000 499,741,000 471,831,000 469,415,000 362,739,000 360,823,000 325,886,000 310,014,000 308,801,000 307,587,000 306,040,000 304,733,000 303,006,000 301,305,000 299,215,000 296,800,000 288,060,000 1,702,000 
        accumulated other comprehensive income
      		8,618,000 5,229,000 2,545,000 5,290,000 6,639,000    -4,000 13,000 49,000 1,000 6,000  -39,000 -130,000 -113,000 34,000 27,000 39,000 34,000 53,000   9,000 14,000 27,000 86,000 110,000 127,000 2,000 4,000   2,000  12,000 29,000 60,000 77,000 135,000 43,000 44,000 32,000 39,000  
        accumulated deficit
      		-1,201,589,000 -1,164,998,000 -1,132,082,000 -1,033,564,000 -1,007,630,000 -955,527,000 -890,976,000 -867,009,000 -858,753,000 -824,890,000 -797,522,000 -777,518,000 -753,237,000 -737,523,000 -720,715,000 -702,625,000 -680,673,000 -663,711,000 -647,230,000 -624,444,000 -607,542,000 -592,511,000 -572,647,000 -585,785,000 -562,775,000 -524,785,000 -486,011,000 -455,872,000 -413,678,000 -375,576,000 -364,227,000 -342,559,000 -324,192,000 -303,142,000 -284,907,000 -261,781,000 -248,345,000 -235,323,000 -223,668,000 -215,746,000 -207,177,000 -198,883,000     
        total stockholders’ equity
      		81,777,000 57,197,000     11,060,000 18,851,000 25,062,000 57,374,000 83,180,000 101,591,000 33,025,000 47,391,000 62,873,000 53,892,000 72,771,000 87,559,000 95,655,000 88,205,000 102,609,000 115,274,000 129,773,000 114,373,000 122,983,000 7,174,000 21,517,000 49,307,000 88,460,000 124,299,000 107,613,000 126,867,000 38,552,000 57,684,000 40,985,000 48,232,000 60,472,000 72,297,000 82,436,000 89,068,000 95,968,000 102,469,000 112,243,000 125,261,000 131,905,000  
        total liabilities, preferred stock and stockholders’ equity
      		227,808,000                                              
        liabilities, convertible preferred stock and stockholders’ (deficit) equity
      		                                              
        convertible preferred stock:
      		                                              
        series b convertible preferred stock, 0.0001 par value...
      		      21,159,000 21,159,000 21,159,000 21,159,000 21,159,000 21,159,000 21,159,000                                  
        series a convertible preferred stock, 0.0001 par value...
      		                                              
        total liabilities, convertible preferred stock and stockholders’ equity
      		 246,442,000 176,852,000 196,264,000   126,378,000 105,747,000 123,539,000 149,718,000 176,153,000 191,758,000 120,877,000                                  
        total stockholders’
      		  -15,526,000                                            
        accrued expenses, long-term
      		   7,553,000                                           
        total stockholders’ (deficit) equity
      		   36,056,000 -32,433,000 -28,893,000                                         
        accrued expenses
      		    25,391,000 25,952,000 22,153,000 17,195,000 17,384,000 17,928,000 16,314,000 13,756,000 13,938,000 14,983,000 14,788,000 17,658,000 13,294,000 15,621,000 12,257,000 10,739,000 8,808,000 14,660,000 23,164,000 21,449,000 18,010,000 19,365,000 21,289,000 19,372,000 19,828,000 21,108,000 38,664,000 12,234,000 7,578,000 7,942,000 12,255,000 4,241,000 4,424,000 6,896,000 4,258,000 3,776,000 3,529,000 6,098,000 7,171,000 6,478,000 5,254,000 873,000 
        total liabilities, convertible preferred stock and stockholders’ (deficit) equity
      		    131,698,000 101,538,000                                         
        deferred liabilities
      		         327,000 1,035,000 744,000 1,403,000 710,000 965,000                                
        preferred stock tranche liability
      		        10,200,000 4,189,000 7,260,000 7,460,000 3,510,000                                  
        current portion of long-term debt
      		      9,870,000 4,926,000               9,300,000 4,586,000      5,716,000 3,528,000 1,384,000               
        convertible senior notes
      		          297,000 290,000 282,000 275,000 268,000 262,000 255,000 249,000 243,000 20,326,000 19,672,000 19,051,000 20,841,000 20,381,000 19,938,000 68,556,000 101,249,000 99,163,000 97,159,000 95,231,000                 
        other long-term liabilities
      		          51,000                                    
        liabilities and stockholders’ equity
      		                                              
        total liabilities and stockholders’ equity
      		             95,050,000 111,095,000 100,409,000 116,148,000 108,662,000 111,877,000 123,890,000 136,901,000 154,349,000 217,770,000 198,532,000 208,154,000 145,046,000 192,600,000 218,541,000 243,365,000 277,236,000 183,155,000 172,918,000 68,411,000 89,791,000 63,139,000 61,839,000 76,249,000 83,629,000 89,044,000 95,423,000 102,564,000 113,094,000 123,666,000 135,696,000 142,003,000  
        long-term investments
      		                   5,992,000 5,998,000 5,995,000                       4,001,000 8,994,000 
        derivative liability, short-term
      		                         450,000                     
        other non-current liabilities
      		                       870,000 870,000 870,000 870,000 500,000 500,000 1,123,000 566,000 399,000 101,000 151,000 201,000 248,000 295,000          
        accumulated other comprehensive loss
      		                                              
        liability classified stock-based compensation awards
      		                                         69,000 47,000 360,000 256,000  
        other liabilities
      		                                     341,000 388,000 430,000 472,000 516,000 559,000 598,000 637,000  
        convertible preferred stock, 0.0001 par value...
      		                                              
        deficit accumulated during the development stage
      		                                              
        liability for shares subject to repurchase
      		                                             36,000 
        liabilities, redeemable convertible preferred stock and stockholders’ deficit
      		                                              
        deferred rent
      		                                             74,000 
        obligation to issue warrant
      		                                             406,000 
        commitments and contingencies
      		                                              
        series a redeemable convertible preferred stock, 0.0001 par value...
      		                                             15,939,000 
        series b redeemable convertible preferred stock, 0.0001 par value...
      		                                             31,948,000 
        series c redeemable convertible preferred stock, 0.0001 par value...
      		                                             20,254,000 
        total stockholders’ deficit
      		                                              
        total liabilities, redeemable convertible preferred stock and stockholders’ deficit
      		                                             59,037,000 
      Cashflow Statements:
      Quarterly
      Annual
        Unit: USD2026-03-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 
                                                  
          operating activities
        		                                          
          net loss
        		-36,591,000 -98,518,000 -25,934,000 -52,103,000 -64,551,000 -23,967,000 -8,256,000 -33,863,000 -27,368,000 -20,004,000 -24,281,000 -15,714,000 -16,808,000 -18,090,000 -21,952,000 -16,962,000 -16,481,000 -22,786,000 -16,902,000 -15,031,000 -19,864,000 13,138,000 -38,774,000 -30,139,000 -42,194,000 -38,102,000 -11,349,000 -21,668,000 -18,367,000 -21,050,000 -18,235,000 -23,126,000 -13,436,000 -13,005,000 -11,655,000 -7,922,000 -8,569,000 -8,294,000 -11,863,000 -15,445,000 -15,377,000 -15,180,000 
          adjustments to reconcile net loss to net cash from operating activities:
        		                                          
          depreciation
        		 2,000 0 10,000 7,000 7,000 6,000 6,000 5,000 5,000 22,000 30,000 29,000 30,000 29,000 30,000 30,000 30,000 65,000 81,000 81,000 261,000 94,000 108,000 114,000 113,000 104,000 100,000 667,000 125,000 128,000 138,000 144,000 146,000         
          amortization of acquired intangible assets
        		279,000 290,000                                         
          non-cash operating lease cost
        		-27,000 -18,000 -21,000 -23,000 -30,000 -51,000                                     
          stock-based compensation expense
        		2,046,000 2,178,000 3,413,000 1,788,000 2,019,000 1,935,000 1,905,000 1,483,000 1,598,000 1,517,000 1,432,000 1,313,000 1,287,000 1,356,000 1,758,000 1,646,000 1,574,000 1,987,000 2,170,000 1,980,000 2,933,000 2,156,000 1,311,000 1,915,000 3,065,000 2,248,000 1,763,000 2,041,000 1,539,000 1,328,000 963,000 1,660,000 1,213,000 1,197,000 1,547,000 1,307,000 1,727,000 1,706,000 2,039,000 2,375,000 2,537,000 3,134,000 
          amortization of deferred financing costs, debt discounts and premiums and discounts on available-for-sale marketable securities
        		-119,000 0 -1,000 30,000 207,000 201,000 6,000 -419,000 -837,000 -371,000 112,000 -36,000 -3,000 120,000 94,000 17,000 44,000 7,959,000 692,000 636,000 554,000 506,000 2,705,000 1,611,000 1,207,000 1,608,000 1,479,000 157,000 95,000 83,000 53,000 65,000 59,000 46,000         
          change in fair value of warrant liability
        		-9,323,000 55,881,000 -20,320,000 2,416,000 32,606,000                                      
          non-cash change in fair value of notes
        		186,000 1,105,000 1,450,000 3,115,000                                       
          loss on debt extinguishment
        		 0 0 1,826,000                                       
          changes in operating assets and liabilities:
        		                                          
          accounts receivable
        		-1,345,000 -4,640,000       0 2,000 -2,000 31,000 43,000 57,000 2,513,000 -2,128,000 -411,000 371,000 649,000 -886,000 5,446,000 -4,185,000 -321,000 -814,000 -831,000 -252,000 10,256,000                
          inventory
        		-454,000 -626,000                   0 6,316,000 -2,618,000 -184,000 12,000 21,000 -196,000                
          prepaid expenses, other current assets and other assets
        		-857,000 -1,103,000 777,000 -1,572,000 1,288,000 -1,806,000 569,000 -647,000 -2,876,000 -1,442,000 581,000 -2,089,000 -605,000 -262,000 1,101,000 510,000 276,000 912,000 -932,000 -1,814,000 -450,000 3,903,000 223,000 -666,000 660,000 -1,094,000 -22,000 -688,000 237,000 -694,000 -372,000 908,000 -387,000 -1,092,000         
          accounts payable
        		-2,846,000 497,000 848,000 3,173,000 -412,000 -2,240,000 -771,000 265,000 2,066,000 639,000 -424,000 2,000 -458,000 3,653,000 -688,000 92,000 1,661,000 -754,000 -1,058,000 774,000 -3,002,000 2,440,000 813,000 -2,689,000 2,938,000 -1,660,000 -1,060,000 3,544,000 642,000 -2,078,000 1,778,000 538,000 -1,864,000 4,594,000 2,133,000 -148,000 -485,000 -1,347,000 303,000   891,000 
          accrued expenses and other liabilities
        		-3,065,000 15,000,000 3,977,000 2,664,000 3,767,000 4,958,000 -182,000 -544,000 1,607,000 2,970,000 -594,000 -1,045,000 195,000 -2,870,000 4,486,000 -2,449,000 3,410,000 1,490,000 1,922,000 -5,026,000 -8,950,000 1,639,000 -1,714,000 2,206,000 -88,000 -2,111,000 4,501,000 4,616,000 4,920,000 -135,000 -4,642,000 7,967,000 -210,000 -2,538,000 2,591,000 440,000 205,000 -2,613,000 -1,116,000 654,000   
          net cash from operating activities
        		-52,116,000 -36,216,000 -32,663,000 -38,676,000 -25,099,000 -23,795,000 -27,570,000 -28,307,000 -29,681,000 -16,589,000 -19,904,000 -20,286,000 -16,616,000 -15,082,000 -12,694,000 -19,281,000 -9,933,000 -10,827,000 -13,424,000 -19,318,000 -21,703,000 44,747,000 -37,221,000 -27,848,000 -34,669,000 -38,780,000 -19,188,000 -22,560,000 -10,313,000 -22,454,000 -20,327,000 -11,850,000 -14,481,000 -10,652,000 -5,952,000 -6,019,000 -6,691,000 -10,822,000     
          capital expenditures
        		0 0 0  0 0 -7,000 -14,000 0 0 0 0 0 0 0  0 0 0  0 205,000 0 0 0  -263,000 -567,000 -217,000 67,000 0 0 0 0 0 0 0      
          free cash flows
        		-52,116,000 -36,216,000 -32,663,000  -25,099,000 -23,795,000 -27,577,000 -28,321,000 -29,681,000 -16,589,000 -19,904,000 -20,286,000 -16,616,000 -15,082,000 -12,694,000  -9,933,000 -10,827,000 -13,424,000  -21,703,000 44,952,000 -37,221,000 -27,848,000 -34,669,000  -19,451,000 -23,127,000 -10,530,000 -22,387,000 -20,327,000 -11,850,000 -14,481,000 -10,652,000 -5,952,000 -6,019,000 -6,691,000      
          investing activities
        		                                          
          purchases of investments
        		-16,015,000        -12,564,000 -70,079,000 0 -13,804,000 -2,475,000 -10,353,000 -1,000 -4,986,000 -33,184,000 0 -35,707,000 -17,551,000   -20,937,000 -35,549,000 0 -37,637,000 -110,540,000    -1,496,000 0 0 -6,461,000 -21,880,000 -19,823,000 -4,052,000 -36,346,000     
          net cash from investing activities
        		-16,015,000    0 0 28,993,000 30,979,000 12,436,000 -70,079,000 14,000,000 -804,000 13,025,000 4,647,000 29,249,000 19,264,000 66,000 10,000,000 2,393,000 -12,372,000 -79,380,000 -6,000 25,126,000 17,594,000 46,530,000 363,000 -126,803,000 -15,479,000 -530,000 4,435,000 4,509,000 21,325,000 14,023,000 4,096,000 1,027,000 3,729,000 31,108,000 1,104,000     
          financing activities
        		                                          
          proceeds from the issuance of common stock and pre-funded warrants
        		 0   0    0 -486,000                                 
          repayment of vendor financing arrangement
        		-1,250,000                                          
          proceeds from exercise of warrants
        		29,371,000 18,083,000 9,757,000 4,083,000                                       
          proceeds from long-term debt
        		 0 0 75,000,000     0 0 0 14,918,000 0 0 -624,000 24,772,000            0   12,425,000 0 0 2,386,000         
          repayment of long-term debt
        		 0 0 -42,580,000                                       
          proceeds from insurance premium financing
        		736,000 0 0 1,180,000 0 0 0 1,298,000 0 0 0 1,430,000                               
          payments on insurance premium financing
        		-207,000 -278,000 -274,000 -440,000 -133,000 -393,000 -385,000 -387,000 -146,000 -433,000 -425,000 -426,000                               
          proceeds from the exercise of stock options and employee stock purchase program
        		42,000 74,000 0 22,000 0 20,000 136,000 85,000 0 28,000 0 29,000 0 90,000 92,000 100,000 8,000 261,000 518,000 300,000 1,045,000 147,000 0                    
          net cash from financing activities
        		28,692,000 17,879,000 79,416,000 67,427,000 742,000 53,599,000 -405,000 846,000 -446,000 -891,000 91,481,000 44,050,000 0 25,624,000 708,000 25,452,000 6,805,000 169,000 489,000 -578,000 -36,606,000 137,000 -12,704,000 494,000 9,694,000 75,000 145,469,000 74,000 115,320,000 299,000 46,724,000 14,212,000 -138,000 2,386,000     51,000   55,350,000 
          increase in cash, cash equivalents and restricted cash
        		-39,439,000 -26,616,000 46,753,000 28,751,000 -24,357,000 29,804,000 1,018,000 3,518,000 -17,691,000 -87,559,000 85,577,000 22,960,000 -3,591,000 15,189,000 17,263,000 25,435,000  -658,000 -10,542,000 -32,268,000 -137,689,000 44,878,000 -24,799,000 -9,760,000   -522,000 -37,965,000               
          cash, cash equivalents and restricted cash at beginning of period
        		205,231,000 0 0 89,059,000 0 0 0 79,076,000 0 0 0 75,789,000 0 0 0 21,493,000 0 0 0 68,023,000 0 0 0 0 0 130,608,000 0 0 0 82,338,000             
          cash, cash equivalents and restricted cash at end of period
        		165,792,000 -26,616,000 46,753,000 117,810,000 -24,357,000 29,804,000 1,018,000 82,594,000 -17,691,000 -87,559,000 85,577,000 98,749,000 -3,591,000 15,189,000 17,263,000 46,928,000 -3,062,000 -658,000 -10,542,000 35,755,000 -137,689,000 44,878,000 -24,799,000 -9,760,000 21,555,000 92,266,000 -522,000 -37,965,000 104,477,000 64,618,000             
          supplemental disclosure of non-cash investing and financing activities
        		                                          
          conversion of warrant liability into additional paid-in capital upon warrant exercise
        		26,324,000                                          
          right of use assets obtained in exchange for operating lease liabilities
        		2,515,000                                          
          issuance costs included in accounts payable and accrued expenses
        		   64,000                                       
          change in fair value of preferred stock tranche liability
        		    0 0 -10,200,000 6,011,000 -3,071,000 -200,000 3,950,000 -3,430,000                               
          grant receivable
        		    0 625,000 -599,000 -226,000                                   
          deferred liabilities
        		    0 0 0 -327,000 -708,000 291,000 -659,000 693,000 -255,000                              
          purchases of property and equipment
        		    0 0 -7,000 -21,000         0 0 0 -196,000 0 -6,000     -263,000 -567,000 -575,000 -102,000     0        
          purchases of intangible asset
        		                                          
          maturities of investments
        		    0 0 29,000,000 31,000,000 25,000,000 0 14,000,000 13,000,000 15,500,000 15,000,000 29,250,000 24,250,000 33,250,000 10,000,000 38,100,000 5,375,000 0 0 46,063,000 53,150,000 46,530,000 38,000,000 6,000,000 0 0 4,500,000 6,005,000 21,325,000 14,023,000 10,557,000 22,907,000 23,550,000 35,160,000 37,450,000 63,548,000 52,385,000 25,949,000 31,123,000 
          fees paid to lenders for loan agreement amendment
        		       -150,000                                   
          payments on deferred issuance costs
        		                                          
          purchases of intangible asset in accounts payable and accrued expenses
        		                                          
          accrued expenses, long term
        		                                          
          conversion of warrant liability to additional paid-in capital upon warrant exercise
        		  12,669,000 5,869,000                                       
          proceeds from the issuance of common stock
        		   30,162,000         0 25,534,000 1,240,000 580,000     0 -10,000     0 -301,000 105,158,000 299,000 33,948,000            
          supplemental disclosure
        		                                          
          cash paid for interest
        		                                          
          purchases of property and equipment included in accounts payable and accrued expenses
        		       7,000             0 211,000                     
          payments for loan amendment
        		    0 0                                     
          proceeds from issuance of series b convertible preferred stock
        		        0 0 0 28,099,000                               
          repayment of 2018 notes
        		                                          
          proceeds from the issuance of warrants
        		    0                                      
          issuance of preferred stock tranche liability
        		        0 0 0 6,940,000                               
          conversion of series b convertible preferred stock to common stock
        		                                          
          conversion of warrant liability to common stock upon warrant exercise
        		                                          
          right of use asset obtained in exchange for operating lease liability
        		                                          
          other long-term liabilities
        		                    0  0                    
          payments of deferred issuance costs
        		                                          
          amortization of right-of-use asset and lease liability
        		       -46,000 -46,000 -47,000 -41,000 -41,000 -41,000 -41,000 -35,000 -37,000 -36,000 -36,000 -30,000 -32,000 -31,000 -30,000 27,000 42,000 55,000 57,000                 
          settlement of restricted stock for tax withholdings
        		                1,000 -19,000 -29,000 -878,000                       
          conversion of 2020 notes into common stock
        		                0                          
          deferred financing costs included in accounts payable and accrued expenses
        		               624,000                           
          amortization of acquired intangible asset
        		                    0 8,000 392,000 392,000 393,000 392,000                 
          change in fair value of interest make whole provision for 2019 notes
        		                     0                     
          intangible assets & property, plant and equipment
        		                    0                      
          interest make-whole payments on the 2019 notes
        		                    0 0                     
          common stock issuance costs included in accounts payable and accrued expenses
        		                  0 15,000 0 -10,000 0 0 0 15,000 0 -301,000 281,000 35,000             
          conversion of 2019 notes into common stock
        		                    0 0                     
          purchases of property and equipment including in accounts payable and accrued expenses
        		                                          
          change in fair value of conversion option of 2020 notes on exchange
        		                                          
          settlement of restricted stock for tax withholdings included in accrued expenses
        		                                          
          payment of deferred offering costs
        		                                          
          deferred offering costs included in accounts payable and accrued expenses
        		                                          
          settlement of restricted stock units for tax withholdings included in accrued expenses
        		                  9,000 9,000 711,000 42,000                     
          receivables related to stock option exercises in prepaid expenses and other current assets
        		                   157,000                       
          proceeds from long-term debt, net of issuance costs
        		                      -24,000 0                   
          repayment of long-term, debt
        		                                          
          principal payments on the 2019 notes
        		                                          
          decrease in cash, cash equivalents and restricted cash
        		                         -38,342,000    -17,720,000             
          change in fair value of conversion option of notes on exchange
        		                                          
          change in fair value of interest make whole provision and conversion option for notes
        		                                          
          gain on sale of fixed assets
        		                          0 0 -46,000 -33,000             
          sales of property and equipment
        		                          0 0 45,000 37,000             
          acquisition of intangible asset
        		                                          
          proceeds from issuance of convertible senior notes, net of issuance costs
        		                                          
          principal payments on the convertible senior notes
        		                                          
          deferred debt financing costs
        		                              0 0           
          conversion of notes into common stock
        		                                          
          acquired intangible assets included in intangible assets, net and accrued expenses
        		                                          
          proceeds from the exercise of stock options
        		                        0 75,000 172,000 375,000   351,000        0 4,000 2,000 7,000 
          purchases of property and equipment in accounts payable
        		                            358,000 169,000            8,000 
          change in fair value of conversion option for convertible senior notes
        		                                          
          cash used to settle restricted stock liability
        		                                          
          supplemental disclosure of non-cash financing activities
        		                                          
          supplemental disclosure of non-cash investing activities
        		                                          
          deferred financing costs in accounts payable and accrued expenses
        		                                 140,000         
          loss on disposal of fixed assets
        		                                          
          liability classified stock-based compensation awards
        		                                  0 0 0 -69,000     
          decrease in restricted cash
        		                                  0        
          increase in cash and cash equivalents
        		                              30,906,000 23,687,000 -596,000 -4,170,000 -4,925,000 -2,290,000       
          cash and cash equivalents at beginning of period
        		                              0 0 0 32,349,000 0 0 0 24,870,000 0 0 0 33,901,000 
          cash and cash equivalents at end of period
        		                              30,906,000 23,687,000 -596,000 28,179,000 -4,925,000 -2,290,000 24,417,000 15,147,000 5,039,000 -15,341,000 5,047,000 30,125,000 
          supplemental disclosures
        		                                          
          supplemental disclosure non-cash financing activities
        		                                          
          depreciation and amortization
        		                                  152,000 159,000 176,000 183,000 188,000 189,000 189,000 188,000 
          amortization of premiums and discounts on available-for-sale marketable securities
        		                                  2,000 -50,000 -80,000 -12,000    58,000 
          non-cash expense related to the purchase of technology rights
        		                                          
          net proceeds from the issuance of common stock and restricted common stock
        		                                          
          proceeds from the issuance of common stock included in prepaid expenses and other current assets
        		                                         1,972,000 
          prepaid expenses and other current assets
        		                                   195,000 335,000 -376,000     
          decrease in cash and cash equivalents
        		                                     -9,723,000     
          public offering costs in accounts payable and accrued expenses and other liabilities
        		                                         55,000 
          non-cash expense related to purchase of technology rights
        		                                          
          changing in operating assets and liabilities:
        		                                          
          increase in restricted cash
        		                                          
          amortization of premiums and discounts on available for sale marketable securities
        		                                       79,000   
          common stock issued to purchase technology rights
        		                                          
          net cash (used in) provided by investing activities
        		                                          
          net proceeds from the issuance of common stock
        		                                          
          cash used to settle restricted stock liability awards
        		                                          
          (decrease) increase in cash and cash equivalents
        		                                          
          net proceeds from the sale of common stock
        		                                        8,150,000 55,566,000 
          net cash provided by (used in) financing activities
        		                                          
          adjustments to reconcile net loss to net cash used in operating activities:
        		                                          
          supplemental disclosure of non-cash financing and investing activities
        		                                          
          net income
        		                                          
          adjustments to reconcile net income to net cash used in operating activities:
        		                                          
          common stock issued in exchange for license
        		                                          
          obligation to issue a warrant in exchange for license
        		                                          
          change in fair value of obligation to issue warrant
        		                                          
          other assets
        		                                          
          accrued expenses and deferred rent
        		                                          
          proceeds from issuance of redeemable convertible preferred stock
        		                                          
          supplemental disclosure of non-cash financing activity
        		                                          
          accretion of redeemable convertible preferred stock to redemption value