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Twist Bioscience Corporation
(NASDAQ:TWST) 

TWST stock logo

Twist Bioscience Corporation, a synthetic biology company, manufactures and sells synthetic DNA-based products. The company's DNA synthesis platform enables the manufacturing of synthetic DNA by writing DNA on a silicon chip. It offers synthetic DNA-based products, including synthetic genes, tools f...

Founded: 2013
Full Time Employees: 525
CEO / Founder: Emily Leproust 
Sector: Healthcare
Industry: Diagnostics & Research
Pharmaceuticals
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At a glance:
Bull Thesis:
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Moat:
Income Statements:
Quarterly
Annual
    Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 
                                   
      revenues[1]
    		110,715,000                               
      costs and expenses:
    		                               
      cost of revenues
    		53,593,000 49,726,000 48,172,000 44,760,000 46,765,000 45,873,000 46,477,000 46,193,000 44,420,000 42,536,000 42,424,000 41,845,000 41,669,000 29,442,000 31,586,000 30,974,000 29,714,000 27,056,000 22,497,000 20,933,000 19,028,000 18,162,000 17,577,000 16,472,000 13,564,000 13,792,000 12,385,000 11,394,000 11,789,000 11,857,000  
      research and development expenses
    		19,695,000 17,130,000 17,014,000 18,047,000                            
      selling, general and administrative expenses[1]
    		76,085,000                               
      litigation settlement costs, net of recoveries
    		7,205,000                               
      total costs and expenses
    		156,578,000 136,598,000 128,943,000 126,177,000                            
      income from operations
    		-45,863,000 -32,900,000 -29,934,000 -30,120,000 -41,560,000 -34,644,000 -36,043,000 -88,922,000 -48,889,000 -46,977,000 -50,112,000 -60,781,000 -61,637,000 -44,630,000 -56,871,000 -61,163,000 -60,802,000 -55,940,000 -39,811,000 -42,118,000 -38,004,000 -32,793,000 -23,967,000 -28,196,000 -32,086,000 -55,830,000 -31,568,000 -28,121,000 -26,263,000 -22,897,000  
      yoy
    		10.35% -5.03% -16.95% -66.13% -14.99% -26.25% -28.08% 46.30% -20.68% 5.26% -11.88% -0.62% 1.37% -20.22% 42.85% 45.22% 59.99% 70.59% 66.11% 49.38% 18.44% -41.26% -24.08% 0.27% 22.17% 143.83%      
      qoq
    		39.40% 9.91% -0.62% -27.53% 19.96% -3.88% -59.47% 81.89% 4.07% -6.26% -17.55% -1.39% 38.11% -21.52% -7.02% 0.59% 8.69% 40.51% -5.48% 10.83% 15.89% 36.83% -15.00% -12.12% -42.53% 76.86% 12.26% 7.07% 14.70%   
      operating margin %
    		-Infinity% -31.73% -30.23% -31.36% -44.79% -39.05% -42.55% -109.15% -64.92% -65.70% -74.85% -95.36% -102.42% -82.28% -99.24% -109.00% -126.34% -133.13% -104.90% -120.28% -121.79% -116.45% -73.90% -132.96% -166.27% -325.27% -200.60% -206.77% -193.72% -199.24%  
      interest income
    		1,710,000 2,175,000 2,633,000 2,690,000 2,801,000 3,240,000 3,620,000 3,663,000 3,941,000 4,120,000 3,893,000 3,968,000 3,464,000 3,040,000 1,928,000 722,000 259,000 154,000 58,000 86,000 157,000 134,000 111,000 247,000 576,000 564,000 789,000 804,000 775,000 664,000  
      other income, net[1]
    		175,000                               
      income before income taxes
    		-43,978,000 -30,254,000 -26,881,000 20,581,000 -39,153,000 -31,497,000 -34,751,000 -85,380,000 -45,147,000 -42,888,000 -46,465,000 -56,773,000 -58,480,000 -41,748,000 -50,823,000 -60,666,000 -60,817,000 -55,968,000 -40,901,000 -42,414,000 -37,858,000 -32,854,000 -24,056,000 -28,186,000 -31,707,000 -55,601,000 -31,068,000 -27,862,000 -25,849,000 -22,596,000  
      income tax expense
    		-43,000 -253,000 -257,000 -191,000 -175,000 -97,000                          
      net income
    		-44,021,000 -30,507,000 -12,633,000 20,390,000 -39,328,000 -31,594,000                          
      yoy
    		11.93% -3.44%                              
      qoq
    		44.30% 141.49% -161.96% -151.85% 24.48%                           
      net income margin %
    		-Infinity% -29.42% -12.76% 21.23% -42.38% -35.61% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0%  
      other comprehensive loss:
    		                               
      change in unrealized gain on investments
    		-85,000 18,000 72,000 -25,000 30,000 -66,000 147,000 -21,000 -57,000    647,000    -1,113,000 277,000 -4,000 -12,000   13,000 -74,000 12,000  36,000 3,000 20,000   
      foreign currency translation adjustment
    		17,000 38,000 165,000 -177,000 -25,000 -61,000 66,000 -54,000 -38,000 57,000 -323,000 -538,000 73,000 -366,000 -666,000 -498,000 275,000 -94,000 122,000 250,000 38,000 63,000  -5,000 11,000 -7,000 28,000 250,000 -180,000 -56,000  
      comprehensive loss
    		-44,089,000 -30,451,000   -39,323,000 -31,721,000 -34,442,000 -85,646,000 -45,587,000 -42,817,000 -46,364,000 -58,141,000 -58,436,000 -43,058,000 -51,581,000 -61,419,000 -61,506,000 -45,380,000 -41,124,000 -39,799,000 -37,871,000 -32,845,000 -24,365,000 -28,286,000 -31,745,000 -55,629,000 -31,117,000 -27,663,000 -26,093,000 -22,702,000  
      net income per share
    		-0.71 -0.5 -0.45 0.34 -0.66 -0.53 -0.59 -1.47 -0.79 -0.75 -0.81 -1.01 -1.04 -0.74 -0.89 -1.08 -1.13 -0.91 -0.83 -0.82 -0.78 -0.72 -0.48 -0.67 -0.85 -1.69 -0.95 -0.92 -0.93 -1.18  
      weighted-average shares used for eps calculation
    		61,702 61,080 59,808 59,995 59,649 59,162 58,016 58,145 57,779 57,497 56,885 57,041 56,777 56,444 53,885 56,287 53,472 49,912 48,251 48,963 48,709 46,000 39,190 41,838,498 37,163,684 32,976,145 27,461,844 30,290,150 27,891,700 19,187,533  
      revenues
    		 103,698,000 99,009,000 96,057,000 92,793,000 88,713,000 84,710,000 81,464,000 75,302,000 71,498,000 66,946,000 63,740,000 60,180,000 54,243,000 57,306,000 56,113,000 48,127,000 42,018,000 37,951,000 35,018,000 31,204,000 28,161,000 32,432,000 21,207,000 19,297,000 17,164,000 15,737,000 13,600,000 13,557,000 11,492,000  
      yoy
    		 16.89% 16.88% 17.91% 23.23% 24.08% 26.53% 27.81% 25.13% 31.81% 16.82% 13.59% 25.04% 29.09% 51.00% 60.24% 54.23% 49.21% 17.02% 65.12% 61.70% 64.07% 106.09% 55.93% 42.34% 49.36%      
      qoq
    		 4.74% 3.07% 3.52% 4.60% 4.73% 3.98% 8.18% 5.32% 6.80% 5.03% 5.92% 10.95% -5.34% 2.13% 16.59% 14.54% 10.72% 8.38% 12.22% 10.81% -13.17% 52.93% 9.90% 12.43% 9.07% 15.71% 0.32% 17.97%   
      selling, general and administrative expenses[2]
    		 69,742,000                              
      other income, net [3]
    		 471,000                              
      selling, general and administrative expenses
    		  63,757,000 63,370,000                            
      impairment of long-lived assets
    		       44,930,000                        
      gain on sale of business
    		   48,847,000                            
      other income, net [2]
    		  420,000 -836,000                            
      other comprehensive income:
    		                               
      comprehensive income
    		  -12,718,500 20,188,000                            
      basic earnings per share:
    		                               
      diluted earnings per share:
    		                               
      operating expenses:
    		                               
      research and development
    		    23,917,000 21,307,000 21,134,000 22,469,000 24,149,000 23,099,000 23,746,000 24,528,000 27,379,000 31,242,000 29,606,000 36,840,000 31,231,000 22,630,000 19,443,000 19,838,000 15,791,000 14,000,000 11,637,000 10,444,000 10,629,000 10,297,000 10,497,000 9,007,000 8,907,000 7,273,000  
      selling, general and administrative
    		    63,671,000 56,177,000 53,142,000 56,794,000 55,622,000 52,840,000 47,391,000 46,057,000 53,965,000 42,324,000 54,159,000 53,693,000 53,998,000 51,098,000 38,243,000 34,478,000 34,389,000 28,792,000 27,185,000 22,487,000 27,190,000 26,405,000 24,423,000 21,320,000 19,124,000 15,259,000  
      total operating expenses
    		    134,353,000 123,357,000 120,753,000 170,386,000 124,191,000 118,475,000 117,058,000 124,521,000 121,817,000 98,873,000 114,177,000 117,276,000 108,929,000 97,958,000 77,762,000 77,136,000 69,208,000 60,954,000 56,399,000 49,403,000 51,383,000 72,994,000 47,305,000 41,721,000 39,820,000 34,389,000  
      interest expense
    		    -143,000 -24,000     -1,000 -1,000 -2,000 -1,000 -26,000  -29,000 -26,000 -83,000 -70,000 -95,000 -118,000 -143,000 -181,000 -215,000 -248,000 -287,000 -318,000 -340,000 -348,000  
      other income
    		    -251,000 -69,000 -2,299,000 -121,000 -199,000 -31,000 -245,000 41,000  -157,000 -461,000 -225,000 -245,000 -156,000 -1,065,000 -312,000 84,000 -77,000 -57,000 -56,000 18,000 -87,000 -2,000 -227,000 -21,000 -15,000  
      restructuring and other costs
    		                               
      change in fair value of contingent considerations and holdbacks
    		           -581,000 -1,196,000 -4,135,000 -1,174,000 -4,231,000 -6,014,000               
      income tax provision
    		      -164,000 -191,000 -345,000 -120,000                      
      net loss attributable to common stockholders
    		      -34,655,000 -85,571,000 -45,492,000 -43,008,000 -46,243,000 -57,395,000 -59,156,000 -41,824,000 -51,115,000 -60,517,000 -60,668,000 -45,563,000 -41,242,000 -40,037,000 -37,919,000 -32,900,000 -24,318,000 -28,207,000 -31,768,000 -55,638,000 -31,181,000 -27,916,000 -25,933,000 -22,639,000  
      change in unrealized loss on investments
    		         134,000 327,000 -208,000  -868,000 -448,500 -404,000          16,000    -7,000  
      restructuring costs
    		          3,168,000 12,672,000                    
      benefit from income taxes
    		          222,000 -622,000   -292,000 149,000 149,000 10,405,000 -341,000 2,377,000            
      other expense
    		            -305,000                   
      income tax benefit
    		            -676,000 -76,000                  
      change in fair value of contingent considerations and indemnity holdbacks
    		                 -2,826,000              
      change in fair value of acquisition consideration
    		                  471,750 1,887,000            
      litigation settlement
    		                         22,500,000      
      provision for income taxes
    		                    -61,000 -46,000 -262,000 -21,000 -61,000 -37,000 -113,000 -54,000 -84,000 -43,000  
      change in unrealized income on investments
    		                    10,000           
      change in unrealized income/(loss) on investments
    		                     -8,000          
    Balance Sheets:
    Quarterly
    Annual
      Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 
                                     
        assets
      		                               
        current assets:
      		                               
        cash and cash equivalents
      		122,670,000 148,591,000 183,049,000 201,373,000 210,437,000 221,403,000 226,316,000 239,142,000 243,348,000 266,269,000 286,470,000 307,459,000 315,196,000 316,681,000 378,687,000 376,249,000 407,627,000 191,624,000 465,829,000 475,279,000 399,329,000 348,789,000 93,667,000 207,853,000 184,395,000 26,032,000 46,735,000 68,212,000 28,693,000 80,757,000 80,757,000 
        short-term investments
      		49,001,000 49,358,000 49,385,000 49,425,000 46,710,000 49,424,000 50,083,000 50,276,000 49,994,000 44,875,000 49,943,000 49,686,000 72,462,000 122,029,000 126,281,000 151,342,000 166,231,000 110,235,000 12,034,000 44,129,000 156,329,000 238,496,000 196,335,000 103,906,000 45,669,000 77,075,000 91,372,000 93,575,000 75,631,000   
        accounts receivable, net[1]
      		64,153,000                               
        inventories
      		33,515,000 32,924,000 28,309,000 25,938,000 20,860,000 23,518,000 24,078,000 28,484,000 30,376,000 30,863,000 32,063,000 36,354,000 39,923,000 44,597,000 39,307,000 43,022,000 44,591,000 40,239,000 31,800,000 21,224,000 15,838,000 13,409,000 12,289,000 13,161,000 10,764,000 7,416,000 7,330,000 5,496,000 4,449,000   
        prepaid expenses and other current assets[1]
      		54,100,000                               
        total current assets
      		323,439,000 303,882,000 332,966,000 339,776,000 338,442,000 345,309,000 346,776,000 361,831,000 371,869,000 390,231,000 424,256,000 445,537,000 489,271,000 541,859,000 596,483,000 624,117,000 664,375,000 385,007,000 546,495,000 576,607,000 607,999,000 634,428,000 334,870,000 344,578,000 260,205,000 129,288,000 160,135,000 182,622,000 120,991,000 95,671,000 95,671,000 
        property and equipment
      		111,226,000 105,119,000 102,283,000 95,351,000 97,143,000 100,669,000 102,520,000 106,339,000 121,339,000 126,225,000 131,830,000 140,778,000 146,539,000 144,850,000 139,441,000 127,011,000 91,814,000 65,135,000 44,122,000 37,864,000 31,975,000 27,153,000 25,466,000 23,870,000 23,266,000 21,339,000 20,835,000 19,817,000 14,940,000 12,331,000 12,331,000 
        operating lease right-of-use assets
      		70,655,000 72,266,000 49,377,000 51,845,000 54,065,000 56,475,000 58,829,000 61,277,000 63,666,000 69,093,000 71,531,000 72,028,000 70,669,000 73,757,000 74,948,000 76,165,000 78,215,000 72,020,000 61,580,000 62,803,000 30,997,000 32,330,000 33,699,000 35,064,000 35,853,000 37,238,000      
        investment in equity securities[1]
      		68,087,000                               
        goodwill
      		82,195,000 82,195,000 82,195,000 82,195,000 85,811,000 85,811,000 85,811,000 85,811,000 85,811,000 85,811,000 85,811,000 85,811,000 85,811,000 85,811,000 85,811,000 85,811,000 85,678,000 84,244,000 22,434,000 22,676,000 1,138,000 1,138,000 1,138,000 1,138,000 1,138,000 1,138,000 1,138,000 1,138,000 1,138,000 1,138,000 1,138,000 
        intangible assets
      		12,996,000 13,162,000 13,425,000 13,688,000 13,951,000 14,215,000 14,478,000 14,741,000 51,898,000 53,190,000 54,483,000 55,775,000 57,068,000 58,361,000 59,738,000 61,115,000 62,493,000 63,921,000 18,262,000 18,562,000 203,000 256,000 307,000 356,000 407,000 458,000 508,000 559,000 610,000 712,000 712,000 
        restricted cash, non-current
      		2,182,000 2,394,000 2,376,000 2,532,000 2,510,000 2,656,000 2,816,000 2,895,000 2,868,000 2,847,000 2,811,000 4,379,000 2,365,000 2,410,000 1,572,000 1,572,000 1,572,000 1,572,000 1,530,000 1,530,000 1,530,000 1,530,000 579,000 579,000 579,000 579,000 579,000 579,000 579,000 579,000 579,000 
        other non-current assets[1]
      		5,434,000                               
        total assets
      		676,214,000 638,085,000 641,861,000 643,605,000 595,615,000 608,580,000 614,323,000 638,118,000 702,846,000 732,815,000 776,403,000 810,332,000 853,924,000 909,970,000 961,378,000  1,021,636,000 786,167,000 702,097,000 725,298,000 677,289,000 699,570,000 398,882,000 408,240,000 323,872,000 192,277,000 186,994,000 206,805,000 140,170,000 115,791,000 115,791,000 
        liabilities and stockholders’ equity
      		                               
        current liabilities:
      		                               
        accounts payable
      		14,682,000 12,493,000 11,094,000 11,985,000 8,063,000 7,503,000 1,630,000 6,626,000 7,703,000 9,256,000 14,052,000 12,184,000 13,236,000 20,113,000 20,092,000 21,014,000 16,815,000 23,073,000 14,900,000 11,268,000 8,528,000 8,932,000 4,830,000 5,973,000 6,932,000 9,106,000 9,760,000 7,835,000 4,505,000 7,531,000 7,531,000 
        accrued compensation
      		27,003,000 18,835,000 31,288,000 28,972,000 24,920,000 21,742,000 33,650,000 31,659,000 25,214,000 20,787,000 25,818,000 27,284,000 24,280,000 23,277,000 27,023,000 27,698,000 21,686,000 18,735,000 22,327,000 19,523,000 14,897,000 11,577,000 14,945,000 11,298,000 8,625,000 8,848,000 10,479,000     
        current portion of operating lease liability
      		10,443,000 12,242,000 13,822,000 15,501,000 15,218,000 15,030,000 14,805,000 14,555,000 14,621,000 14,808,000 14,896,000 13,132,000 13,396,000 14,227,000 13,642,000 14,352,000 14,166,000 12,684,000 8,213,000   6,444,000 6,409,000         
        accrued expenses and other current liabilities
      		67,848,000                               
        total current liabilities
      		119,976,000 80,441,000 91,406,000 87,070,000 74,976,000 69,646,000 71,006,000 73,757,000 67,490,000 65,228,000 73,323,000 72,822,000 72,108,000 83,837,000 90,663,000 92,686,000 84,632,000 80,034,000 63,052,000 54,833,000 40,442,000 37,102,000 36,029,000 31,377,000 30,210,000 57,844,000 30,354,000 25,447,000 18,580,000 18,537,000 18,537,000 
        operating lease liability, net of current portion
      		85,398,000 85,808,000 61,750,000 62,649,000 65,080,000 67,586,000 70,221,000 72,625,000 74,804,000 77,070,000 79,173,000 79,900,000 77,824,000 79,748,000 81,270,000 64,244,000 65,496,000 60,285,000 53,156,000   23,681,000 24,837,000         
        liability related to the sale of future revenue
      		15,000,000 15,000,000 15,000,000 15,000,000 15,000,000 15,000,000                          
        other non-current liabilities[1]
      		746,000                               
        total liabilities
      		221,120,000 181,990,000 168,903,000 165,407,000 155,507,000 152,639,000 141,634,000 146,979,000 142,715,000 142,773,000 152,971,000 152,782,000 149,992,000 163,645,000 171,993,000  158,275,000 159,989,000 121,276,000 114,850,000 63,108,000 61,618,000 62,620,000 59,294,000 59,670,000 89,196,000 34,912,000 30,802,000 24,690,000 26,730,000 26,730,000 
        commitments and contingencies
      		                               
        stockholders’ equity
      		                               
        common stock
      		1,000                               
        additional paid-in capital
      		1,849,838,000 1,806,751,000 1,793,163,000 1,771,502,000 1,753,600,000 1,730,092,000 1,715,119,000 1,699,127,000 1,682,473,000 1,666,797,000 1,657,222,000 1,644,976,000 1,633,217,000 1,617,174,000 1,619,644,000 1,599,355,000 1,580,620,000 1,281,931,000 1,190,828,000 1,179,331,000 1,143,265,000 1,129,165,000 794,630,000 782,949,000 669,919,000 477,053,000 470,425,000 463,229,000 375,043,000 9,346,000 9,346,000 
        accumulated other comprehensive loss
      		-639,000 -571,000 -627,000    -522,000    -756,000                     
        accumulated deficit
      		-1,394,106,000 -1,350,085,000 -1,319,578,000 -1,292,440,000 -1,312,830,000 -1,273,502,000 -1,241,908,000 -1,207,253,000 -1,121,682,000 -1,076,190,000 -1,033,034,000 -986,791,000 -929,396,000 -870,240,000 -828,416,000 -777,301,000 -716,784,000 -656,116,000 -610,553,000 -569,311,000 -529,274,000 -491,355,000 -458,455,000 -434,137,000 -405,930,000 -374,162,000 -318,524,000 -287,343,000 -259,427,000 -210,855,000 -210,855,000 
        total stockholders’ equity
      		455,094,000 456,095,000 472,958,000 478,198,000 440,108,000 455,941,000 472,689,000 491,139,000 560,131,000 590,042,000 623,432,000 657,550,000 703,932,000 746,325,000 789,385,000 820,677,000 863,361,000 626,178,000 580,821,000 610,448,000 614,181,000 637,952,000 336,262,000 348,946,000 264,202,000 103,081,000 152,082,000 176,003,000 115,480,000 -201,422,000  
        total liabilities and stockholders’ equity
      		676,214,000 638,085,000 641,861,000 643,605,000 595,615,000 608,580,000 614,323,000 638,118,000 702,846,000 732,815,000 776,403,000 810,332,000 853,924,000 909,970,000 961,378,000 979,663,000 1,021,636,000 786,167,000 702,097,000 725,298,000 677,289,000 699,570,000 398,882,000 408,240,000 323,872,000 192,277,000      
        accounts receivable, net [1]
      		 50,062,000 57,019,000 49,854,000                            
        prepaid expenses and other current assets [2]
      		 22,947,000 15,204,000 13,186,000                            
        investment in equity securities[3]
      		 54,337,000                              
        other non-current assets [4]
      		 4,730,000 4,902,000                             
        accrued expenses
      		 23,405,000 23,053,000 19,535,000 19,570,000 20,129,000 15,104,000 14,838,000 14,513,000 13,959,000 10,754,000 10,311,000 11,156,000 10,398,000 10,169,000 9,499,000 15,942,000 11,686,000 6,437,000 4,867,000 3,272,000 3,510,000 3,901,000 2,731,000 3,491,000 4,687,000 5,965,000 3,713,000 2,412,000 2,166,000 2,166,000 
        other current liabilities
      		 13,466,000 12,149,000 11,077,000 7,205,000 5,242,000 5,817,000 6,079,000 5,439,000 6,418,000 7,803,000 9,911,000 10,040,000 15,822,000 19,737,000 20,123,000 16,023,000 13,856,000 9,623,000 9,265,000 4,063,000 3,306,000 2,611,000 1,373,000 52,000 999,000 817,000 680,000 894,000 939,000 939,000 
        other non-current liabilities[5]
      		 741,000 747,000                             
        investment in equity securities [3]
      		  54,337,000                             
        investment in equity securities
      		   54,337,000                            
        other non-current assets [3]
      		   3,881,000                            
        other non-current liabilities[4]
      		   688,000                            
        accumulated other comprehensive income
      		   -864,000 -662,000 -649,000  -735,000 -660,000 -565,000  -635,000 111,000 -609,000 -1,843,000 -1,377,000 -475,000 363,000 546,000 428,000 190,000 142,000 87,000 134,000 213,000 190,000 181,000 117,000 -136,000 87,000 87,000 
        accounts receivable
      		    49,949,000 39,315,000 34,903,000 31,988,000 35,993,000 35,354,000 44,064,000 42,580,000 48,187,000 44,437,000 40,294,000 41,195,000 34,877,000 32,872,000 28,549,000 28,116,000 27,290,000 25,492,000 26,376,000 13,347,000 14,831,000 13,054,000 12,104,000 11,697,000 7,998,000 5,419,000 5,419,000 
        prepaid expenses and other current assets
      		    10,486,000 11,649,000 11,396,000 11,941,000 12,158,000 12,870,000 11,716,000 9,458,000 13,503,000 14,115,000 11,914,000 12,309,000 11,049,000 10,037,000 8,283,000 7,859,000 9,213,000 8,242,000 6,203,000 6,311,000 4,546,000 5,711,000 2,594,000 3,642,000 4,220,000 3,467,000 3,467,000 
        other non-current assets
      		    3,693,000 3,445,000 3,093,000 5,224,000 5,395,000 5,418,000 5,681,000 6,024,000 2,201,000 2,922,000 3,385,000 3,872,000 6,902,000 7,425,000 7,674,000 5,256,000 3,447,000 2,735,000 2,823,000 2,655,000 2,424,000 2,237,000 3,799,000 2,090,000 1,912,000 5,360,000 5,360,000 
        other non-current liabilities
      		    451,000 407,000 407,000 597,000 421,000 475,000 475,000 60,000 60,000 60,000 60,000 2,056,000 8,147,000 19,670,000 5,068,000 6,168,000 422,000 210,000 351,000  95,000 144,000 158,000 236,000 282,000 344,000 344,000 
        current portion of long-term debt
      		                  1,552,000 2,365,000 3,168,000 3,333,000 3,333,000 3,333,000 3,333,000 3,333,000 3,333,000 3,333,000 3,333,000 2,500,000 2,500,000 
        total assets [1]
      		               979,663,000                
        total liabilities [1]
      		               158,986,000                
        long term investments
      		                30,587,000               
        long term investment
      		                 106,843,000              
        long-term debt
      		                     625,000 1,403,000 2,170,000 2,925,000 3,669,000 4,400,000 5,119,000 5,828,000 7,218,000 7,218,000 
        current assets
      		                               
        current liabilities
      		                               
        current portion of operating lease liabilities
      		                   7,545,000 6,514,000   6,669,000 7,777,000 8,371,000      
        operating lease liabilities, net of current portion
      		                   53,849,000 22,244,000   25,747,000 26,440,000 27,539,000      
        preferred stock, 0.00001 par value—10,000,000 shares authorized; no shares issued or outstanding
      		                               
        accrued litigation settlement
      		                         22,500,000      
        liabilities, redeemable convertible preferred stock and stockholders’ equity
      		                               
        redeemable convertible preferred stock
      		                             631,000 631,000 
        series a redeemable convertible preferred stock, 0.00001 par value—no shares and 2,854,576 shares authorized as of september 30, 2019 and 2018; no shares and 2,817,723 shares issued and outstanding as of september 30, 2019 and 2018.
      		                               
        series b redeemable convertible preferred stock, 0.00001 par value—no shares and 3,331,878 shares authorized as of september 30, 2019 and 2018; no shares and 3,315,645 shares issued and outstanding as of september 30, 2019 and 2018.
      		                               
        series c redeemable convertible preferred stock, 0.00001 par value—no shares and 2,510,354 shares authorized as of september 30, 2019 and 2018; no shares and 2,491,483 shares issued and outstanding as of september 30, 2019 and 2018.
      		                               
        series d redeemable convertible preferred stock, 0.00001 par value—no shares and 10,475,252 shares authorized as of september 30, 2019 and 2018, respectively; no shares and 10,326,454 shares issued and outstanding as of september 30, 2019 and 2018, respectively.
      		                               
        total redeemable convertible preferred stock
      		                             290,483,000 290,483,000 
        preferred stock, 0.00001 par value—10,000,000 shares and no shares authorized as of september 30, 2019 and 2018, respectively; no shares issued or outstanding as of september 30, 2019 and 2018, respectively.
      		                               
        total liabilities, redeemable convertible preferred stock and stockholders’ equity
      		                          186,994,000 206,805,000 140,170,000 115,791,000  
        accrued payroll
      		                           9,886,000 7,436,000 5,401,000 5,401,000 
        series a redeemable convertible preferred stock, 0.00001 par value—2,854,576 shares and no shares authorized as of september 30, 2018 and june 30, 2019, respectively; 2,817,723 shares and no shares issued and outstanding as of september 30, 2018 and june 30, 2019, respectively.
      		                               
        series b redeemable convertible preferred stock, 0.00001 par value—3,331,878 shares and no shares authorized as of september 30, 2018 and june 30, 2019, respectively; 3,315,645 shares and no shares issued and outstanding as of september 30, 2018 and june 30, 2019, respectively.
      		                               
        series c redeemable convertible preferred stock, 0.00001 par value—2,510,354 shares and no shares authorized as of september 30, 2018 and june 30, 2019, respectively; 2,491,483 shares and no shares issued and outstanding as of september 30, 2018 and june 30, 2019, respectively.
      		                               
        series d redeemable convertible preferred stock, 0.00001 par value—10,475,252 shares and no shares authorized as of september 30, 2018 and june 30, 2019, respectively; 10,326,454 shares and no shares issued and outstanding as of september 30, 2018 and june 30, 2019, respectively.
      		                               
        preferred stock, 0.00001 par value—no shares and 10,000,000 shares authorized as of september 30, 2018 and june 30, 2019, respectively; no shares issued or outstanding as of september 30, 2018 and june 30, 2019, respectively.
      		                               
        series a redeemable convertible preferred stock, 0.00001 par value—2,854,576 shares and no shares authorized as of september 30, 2018 and march 31, 2019, respectively; 2,817,723 shares and no shares issued and outstanding as of september 30, 2018 and march 31, 2019, respectively.
      		                               
        series b redeemable convertible preferred stock, 0.00001 par value—3,331,878 shares and no shares authorized as of september 30, 2018 and march 31, 2019, respectively; 3,315,645 shares and no shares issued and outstanding as of september 30, 2018 and march 31, 2019, respectively.
      		                               
        series c redeemable convertible preferred stock, 0.00001 par value—2,510,354 shares and no shares authorized as of september 30, 2018 and march 31, 2019, respectively; 2,491,483 shares and no shares issued and outstanding as of september 30, 2018 and march 31, 2019, respectively.
      		                               
        series d redeemable convertible preferred stock, 0.00001 par value—10,475,252 shares and no shares authorized as of september 30, 2018 and march 31, 2019, respectively; 10,326,454 shares and no shares issued and outstanding as of september 30, 2018 and march 31, 2019, respectively.
      		                               
        preferred stock, 0.00001 par value—no shares and 10,000,000 shares authorized as of september 30, 2018 and march 31, 2019, respectively; no shares issued or outstanding as of september 30, 2018 and march 31, 2019, respectively.
      		                               
        inventory
      		                             6,028,000 6,028,000 
        series a redeemable convertible preferred stock, 0.00001 par value—2,854,576 shares and no shares authorized as of september 30, 2018 and december 31, 2018, respectively; 2,817,723 shares and no shares issued and outstanding as of september 30, 2018 and december 31, 2018 respectively.
      		                             9,141,000  
        series b redeemable convertible preferred stock, 0.00001 par value—3,331,878 shares and no shares authorized as of september 30, 2018 and december 31, 2018, respectively; 3,315,645 shares and no shares issued and outstanding as of september 30, 2018 and december 31, 2018, respectively.
      		                             25,900,000  
        series c redeemable convertible preferred stock, 0.00001 par value—2,510,354 shares and no shares authorized as of september 30, 2018 and december 31, 2018, respectively; 2,491,483 shares and no shares issued and outstanding as of september 30, 2018 and december 31, 2018, respectively.
      		                             36,726,000  
        series d redeemable convertible preferred stock, 0.00001 par value—10,475,252 shares and no shares authorized as of september 30, 2018 and december 31, 2018, respectively; 10,326,454 shares and no shares issued and outstanding as of september 30, 2018 and december 31, 2018, respectively.
      		                             218,716,000  
        preferred stock, 0.00001 par value—no shares and 10,000,000 shares authorized as of september 30, 2018 and december 31, 2018, respectively; no shares issued or outstanding as of september 30, 2018 and december 31, 2018, respectively.
      		                               
        series a redeemable convertible preferred stock, 0.00001 par value—2,854,576 shares authorized as of september 30, 2017 and 2018; 2,817,723 shares issued and outstanding as of september 30, 2017 and 2018.
      		                              9,141,000 
        series b redeemable convertible preferred stock, 0.00001 par value—3,331,878 shares authorized as of september 30, 2017 and 2018; 3,315,645 shares issued and outstanding as of september 30, 2017 and 2018.
      		                              25,900,000 
        series c redeemable convertible preferred stock, 0.00001 par value—2,510,354 shares authorized as of september 30, 2017 and 2018; 2,491,483 shares issued and outstanding as of september 30, 2017 and 2018.
      		                              36,726,000 
        series d redeemable convertible preferred stock, 0.00001 par value—6,476,580 and 10,475,252 shares authorized as of september 30, 2017 and 2018, respectively; 6,034,089 and 10,326,454 shares issued and outstanding as of september 30, 2017 and 2018, respectively.
      		                              218,716,000 
        stockholders’ deficit
      		                               
        total stockholders’ deficit
      		                              -201,422,000 
        total liabilities, redeemable convertible preferred stock and stockholders’ deficit
      		                              115,791,000 
      Cashflow Statements:
      Quarterly
      Annual
        Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 
                                      
          operating activities
        		                              
          net loss
        		-44,021,000 -30,507,000 -27,138,000 20,390,000 -39,328,000 -31,594,000 -34,655,000 -85,571,000 -45,492,000 -43,008,000 -46,243,000 -57,395,000 -59,156,000 -41,824,000 -51,115,000 -60,517,000 -60,668,000 -45,563,000 -41,242,000 -40,037,000 -37,919,000 -32,900,000 -24,318,000 -28,207,000 -31,768,000 -55,638,000 -31,181,000 -27,916,000 -25,933,000 -22,639,000 
          adjustments to reconcile net loss to net cash from operating activities
        		                              
          depreciation and amortization
        		6,414,000 6,194,000   6,404,000 6,380,000 6,656,000 8,301,000 8,304,000 8,171,000 8,500,000 8,490,000 7,028,000 5,292,000 4,952,000 4,444,000 3,968,000 3,150,000 2,431,000 2,744,000 2,464,000 2,111,000 1,889,000 1,724,000 1,559,000 1,505,000 1,489,000 1,587,000 1,563,000 1,472,000 
          stock-based compensation expense
        		18,936,000 13,273,000 16,083,000                            
          other non-cash adjustments[1]
        		-498,000 -336,000                             
          changes in assets and liabilities:
        		                              
          accounts receivable, net[1]
        		                              
          inventories
        		-590,000 -4,615,000 -2,368,000 -5,078,000 2,657,000 560,000 4,408,000 1,891,000 486,000 1,201,000 4,289,000 3,555,000 4,675,000 -5,281,000 3,701,000 1,550,000 -4,351,000 -8,436,000 -10,575,000 -5,370,000 -2,422,000 -1,122,000 875,000 -2,398,000 -3,347,000 -86,000 -1,834,000 -1,047,000   
          prepaid expenses and other current assets[1]
        		                              
          other non-current assets
        		-641,000 225,000 -965,000 19,000 -266,000 -356,000 -41,000 163,000 9,000 300,000 326,000 -156,000 707,000 499,000 444,000 2,956,000 642,000 3,231,000 -2,320,000 -2,246,000 -146,000 59,000 -130,000 -228,000 -258,000 62,000 -1,622,000 -251,000 201,000 -392,000 
          accounts payable
        		69,000 1,472,000 -284,000 3,194,000 711,000 5,711,000 -4,878,000 -1,202,000 -1,520,000 -4,205,000 1,923,000 -220,000 -7,493,000 3,282,000 6,917,000 1,228,000 -757,000 -5,000 3,348,000 1,396,000 339,000 3,459,000 -1,691,000 -740,000 -2,519,000 -556,000 3,374,000 1,921,000 -1,302,000 -715,000 
          accrued compensation
        		8,168,000 -12,436,000 2,287,000 3,966,000 3,192,000 -11,850,000 1,943,000 6,471,000 4,539,000 -5,078,000 -1,447,000 3,050,000 1,014,000 -3,716,000 -667,000 6,172,000 2,971,000 -3,624,000 2,804,000 4,626,000 3,319,000 -3,357,000 3,633,000 2,680,000 -219,000 -1,629,000     
          accrued and other liabilities
        		                              
          net cash from operating activities
        		-17,559,000 -24,814,000 -11,814,000 -1,400,000 -12,986,000 -21,428,000 -15,320,000 -6,378,000 -19,423,000 -22,973,000 -20,704,000 -23,412,000 -44,288,000 -54,070,000 -1,267,000 -34,125,000 -42,340,000 -46,653,000 -34,803,000 -27,960,000 -24,549,000 -24,932,000 -25,202,000 -23,468,000 -58,671,000 -34,914,000 -23,358,000 -22,082,000 -20,813,000 -21,684,000 
          capital expenditures
        		-7,887,000 -9,974,000 -12,427,000 -9,165,000 -4,144,000 -2,268,000 -2,002,000 -965,000 -603,000 -1,506,000 -2,393,000 -4,509,000 -9,053,000 -11,824,000 -16,462,000 -40,642,000 -31,970,000 -12,783,000 -8,089,000 -6,942,000 -8,401,000 -3,629,000 -2,225,000 -2,848,000 -2,737,000 -2,058,000 -3,893,000 -5,172,000 -3,770,000 -1,922,000 
          free cash flows
        		-25,446,000 -34,788,000 -24,241,000 -10,565,000 -17,130,000 -23,696,000 -17,322,000 -7,343,000 -20,026,000 -24,479,000 -23,097,000 -27,921,000 -53,341,000 -65,894,000 -17,729,000 -74,767,000 -74,310,000 -59,436,000 -42,892,000 -34,902,000 -32,950,000 -28,561,000 -27,427,000 -26,316,000 -61,408,000 -36,972,000 -27,251,000 -27,254,000 -24,583,000 -23,606,000 
          investing activities
        		                              
          purchases of property and equipment
        		-7,887,000 -9,974,000 -12,427,000 -9,165,000 -4,144,000 -2,268,000 -2,002,000 -965,000 -603,000 -1,506,000 -2,393,000 -4,509,000 -9,053,000 -11,824,000 -16,462,000 -40,642,000 -31,970,000 -12,783,000 -8,089,000 -6,942,000 -8,401,000 -3,629,000 -2,225,000 -2,848,000 -2,737,000 -2,058,000 -3,893,000 -5,172,000 -3,770,000 -1,922,000 
          purchase of intangible asset
        		                              
          purchases of investments
        		-4,718,000 -20,509,000 -21,136,000 -2,732,000 -4,932,000 -20,593,000 -21,193,000 -1,746,000 -10,637,000 -18,329,000 -18,090,000 -7,821,000 -27,787,000 -22,647,000 0 0 0 -217,639,000 0 0 15,497,000 -74,292,000 -92,444,000 -103,901,000 0 -6,537,000 -40,310,000 -50,639,000 -22,790,000 -63,835,000 
          proceeds from maturity of investments
        		5,000,000 20,550,000 21,160,000 0 7,650,000 21,325,000 21,910,000 2,000,000 6,000,000 24,000,000 18,236,000 31,000,000 78,000,000 27,500,000 25,000,000 44,805,000 18,676,000 12,000,000 32,000,000 112,000,000 66,494,000 32,000,000  45,600,000 31,500,000 21,000,000  33,100,000   
          cash paid for asset acquisition
        		                              
          cash paid for investment in equity securities
        		                              
          net cash from investing activities
        		-12,706,000 -9,933,000 -12,403,000 -9,397,000 -1,426,000 -1,536,000 -1,285,000 -711,000 -5,240,000 4,165,000 -2,247,000 18,670,000 41,160,000 -6,971,000 2,783,000 4,163,000 -13,294,000 -226,582,000 23,911,000 104,575,000 73,590,000 -45,921,000 -94,669,000 -61,149,000 28,763,000 12,405,000 -1,187,000 -22,706,000 -15,160,000 -65,757,000 
          financing activities
        		                              
          proceeds from exercise of stock options
        		1,789,000 300,000 3,792,000 1,829,000 772,000 2,950,000 1,917,000 2,915,000 1,317,000 951,000 171,000 353,000 251,000 604,000 1,250,000 764,000 895,000 3,105,000 2,873,000 2,570,000 3,032,000 6,084,000 5,518,000 1,916,000 1,387,000 1,674,000     
          proceeds from the issuance of liability related to sale of future revenue
        		  0 0 0 15,000,000                         
          proceeds from issuance under employee stock purchase plan
        		                              
          repurchases of common stock for income tax withholding
        		-8,000 -2,000 -2,000 -3,000 -5,000 -6,000 -8,000 -7,000 -1,536,000 -2,424,000 -1,130,000 -1,014,000 -1,262,000 -999,000 -1,624,000 -2,080,000 -1,492,000 -2,558,000 -2,622,000 -2,476,000 -3,341,000 -2,410,000 -773,000 -450,000 -390,000 -808,000     
          net cash from financing activities
        		4,138,000 298,000 5,574,000 1,826,000 3,196,000 17,944,000 3,627,000 2,908,000 1,828,000 -1,473,000 442,000 -661,000 1,525,000 -395,000 1,240,000 -1,311,000 271,616,000 -1,011,000 1,575,000 -765,000 1,451,000 326,921,000 5,574,000 108,064,000 188,037,000 2,057,000 2,928,000 84,285,000 -1,634,000 72,999,000 
          effect of exchange rates on cash, cash equivalents and restricted cash
        		-6,000 9,000 163,000 -71,000 104,000 -53,000 73,000 2,000 -65,000 116,000 -48,000 -320,000 73,000 268,000 -318,000 -105,000 21,000 83,000 -133,000 100,000 48,000 5,000 27,000 12,000 -27,000 9,000     
          net decrease in cash, cash equivalents, and restricted cash
        		-26,133,000 -34,440,000  -9,042,000 -11,112,000 -5,073,000  -4,179,000 -22,900,000 -20,165,000   -1,530,000 -61,168,000            -20,443,000    -14,442,000 
          cash, cash equivalents, and restricted cash at beginning of period
        		0 185,425,000  0 0 229,132,000  0 0 289,281,000  0 0 380,259,000  0 0 467,359,000  0 0 94,246,000  0 0 47,398,000  0 0 81,537,000 
          cash, cash equivalents, and restricted cash at end of period
        		-26,133,000 150,985,000  -9,042,000 -11,112,000 224,059,000  -4,179,000 -22,900,000 269,116,000  -5,723,000 -1,530,000 319,091,000  -31,378,000 216,003,000 193,196,000  75,950,000 50,540,000 350,319,000  23,459,000 158,102,000 26,955,000  39,497,000 -37,607,000 67,095,000 
          supplemental disclosure of cash flow information
        		                              
          accounts receivable, net [2]
        		 6,826,000                             
          prepaid expenses and other current assets [3]
        		 -7,735,000                             
          accrued expenses
        		 1,509,000 2,317,000 158,000 139,000 3,137,000 283,000 273,000 959,000 2,900,000 1,300,000 -1,615,000 4,147,000 -1,254,000 1,661,000 -1,277,000 1,440,000 445,000 1,569,000 1,591,000 104,000 -149,000 714,000 -325,000 -1,758,000 -1,279,000 2,249,000 1,303,000 619,000 39,000 
          other liabilities
        		 1,316,000   1,935,000 -601,000 -468,000 734,000 -1,055,000 -1,528,000 -1,907,000 2,203,000 -530,000 126,000 -10,378,000 2,122,000 866,000 -34,000 1,919,000 -3,073,000 449,000 677,000 1,402,000 1,177,000 -790,000 189,000 108,000 -102,000 -388,000 135,000 
          income taxes paid, net of refunds
        		 184,000   13,000 3,000 -19,000 24,000 299,000 40,000 179,000 104,000 85,000 52,000 116,000 0 39,000 91,000 54,000 46,000 -80,000 81,000 52,000 0 76,000 44,000 70,000 60,000 108,000 53,000 
          non-cash investing and financing activities
        		                              
          property and equipment additions included in accounts payable and accrued expenses
        		 1,182,000   -807,000 2,136,000  177,000 -438,000 487,000  -61,000 -2,773,000 4,520,000  -2,175,000 -2,742,000 11,479,000  1,580,000 -1,318,000 1,515,000  -752,000 708,000 66,000  1,087,000 -931,000 1,117,000 
          operating lease right-of-use assets obtained in exchange for operating lease liabilities
        		 24,773,000         2,461,000    1,873,000 0 9,071,000 10,423,000 0 33,554,000   0 885,000 0 2,833,000     
          depreciation and amortization expense
        		  6,004,000                            
          impairment of long-lived assets
        		      0                        
          non-cash lease expense, net of tenant improvement allowance
        		                              
          change in fair value of contingent considerations and holdbacks
        		                              
          gain on sale of business
        		  0                            
          other non-cash adjustments
        		  240,000 1,152,000 831,000 -20,000 1,179,000 -478,000                       
          accounts receivable, net [1]
        		  -7,210,000                            
          prepaid expenses and other current assets [2]
        		  -1,895,000                            
          other liabilities [3]
        		                              
          proceeds from sale of business
        		  0                            
          net increase in cash, cash equivalents and restricted cash
        		                              
          cash, cash equivalents, and restricted cash at beginning of year
        		                              
          cash, cash equivalents, and restricted cash at end of year
        		                              
          property and equipment additions included in accrued expenses and accounts payable
        		                              
          other liabilities[3]
        		                              
          proceeds from issuance of common stock under employee stock purchase plan
        		   0    0    0    -1,000    0    0       
          stock-based compensation
        		    20,328,000 11,991,000 12,347,000 13,734,000 13,824,000 11,020,000 11,747,000 10,597,000 10,259,000 -2,325,000 19,048,000 20,043,000 22,465,000 18,108,000 9,247,000 9,176,000 11,553,000 7,022,000 5,131,000 4,071,000 4,197,000 3,697,000 3,363,000 3,032,000 2,911,000 1,864,000 
          accounts receivable
        		    -10,722,000 -4,537,000 -2,954,000 3,997,000 -657,000 8,058,000 -1,812,000 5,542,000 -3,952,000 -4,098,000 662,000 -6,439,000 -1,813,000 -2,032,000 -290,000 -581,000 -2,215,000 884,000 -13,029,000 1,484,000 -1,777,000 -950,000 -577,000 -3,529,000 -1,020,000 -1,559,000 
          prepaid expenses and other current assets
        		    1,133,000 -249,000 567,000 235,000 696,000 -1,116,000 -2,231,000 -344,000 -414,000 -1,177,000 185,000 -1,329,000 -1,316,000 -91,000 -441,000 1,114,000 -688,000 -2,043,000 31,000 -1,761,000 964,000 -2,917,000 868,000 609,000 -365,000 -366,000 
          property and equipment capitalized acquired through tenant improvement allowance
        		                              
          cash flows from operating activities
        		                              
          cash flows from investing activities
        		                              
          cash flows from financing activities
        		                              
          gain on deconsolidation of revelar
        		                              
          business acquisition, net of cash acquired
        		              0 0 0 -8,160,000 0            
          deconsolidation of cash and cash equivalent relating to revelar
        		                              
          proceeds from public offerings, net of underwriting discounts, commissions and offering expenses
        		              -2,000 6,000           0    
          repayments of long-term debt
        		              0 0     -834,000 -833,000 -833,000 -833,000 -834,000 -833,000     
          interest paid
        		              0 0 0 9,000 22,000 36,000 48,000 61,000 75,000 92,000 125,000 146,000 174,000 192,000 206,000 207,000 
          issuance of common stock in connection with the business acquisition
        		          0 1,768,000   0 0 4,608,000 72,514,000             
          tenant improvement allowance capitalized in property and equipment
        		      0 0                       
          conversion of convertible notes
        		          0                    
          non-cash lease expense
        		       144,000 255,000 248,000  454,000 332,000 254,000  985,000 435,000 1,174,000 1,199,000 830,000 -34,000 248,000 196,000 -1,012,000 -463,000 236,000     
          change in fair value of acquisition consideration
        		           -582,000 -1,196,000 -4,135,000                 
          other non cash adjustments
        		         64,000   291,000 287,000                 
          impairment of property and equipment and other assets
        		          3,165,000                    
          deferred tax liability
        		               -132,000 -500,000 -10,545,000             
          other non cash adjustment
        		                              
          net increase in cash, cash equivalents, and restricted cash
        		               -31,378,000 216,003,000 -274,163,000  75,950,000 50,540,000 256,073,000  23,459,000    39,497,000   
          proceeds from (repayments of) long-term debt
        		                 -1,558,000             
          loss on disposal of property and equipment
        		                  0 0 0 2,000     -13,000 194,000 0 8,000 
          discount (premium) accretion on investment securities
        		                  92,000 187,000           
          realized gain on investments
        		                  0 -1,000           
          allowance for doubtful accounts
        		                              
          non-cash interest expense
        		              0 0 0 3,000 9,000 14,000 19,000 25,000 30,000 35,000 41,000 46,000 51,000 57,000 61,000 64,000 
          amortization of debt discount
        		              0 0 0 4,000 11,000 17,000 23,000 30,000 36,000 43,000 49,000 56,000 63,000 67,000 74,000 78,000 
          write off property and equipment
        		              0 0               
          discount accretion on investment securities
        		               266,000 472,000 318,000    122,000 29,000 -11,000 -82,000 -150,000 -281,000 -447,000   
          bad debt expense
        		               34,000               
          contingent consideration and holdbacks
        		                              
          change in fair value of contingent consideration and indemnity holdback
        		                 -2,826,000             
          unrealized currency translation
        		                 70,000             
          deferred offering costs included in accounts payable and accrued expenses
        		                     229,000       -806,000 826,000 
          proceeds from sale of property and equipment
        		                          16,000    
          conversion of redeemable convertible preferred stock warrant liability to equity
        		                          0 0 0 631,000 
          conversion of redeemable convertible preferred stock to common stock
        		                          0 0 0 290,462,000 
          issuance of common stock in connection with the igenomx acquisition
        		                  0            
          bad debts expense
        		                              
          changes in assets and liabilities, net of acquisition:
        		                              
          proceeds from public offerings, net of underwriting discounts and commissions and offering expenses
        		                   -26,000    107,431,000       
          repayments of debt
        		                              
          offering expenses included in accounts payable and accrued expenses
        		                       -76,000       
          accrued litigation settlement
        		                         22,500,000     
          proceeds from public offering, net of underwriting discounts and commissions and offering expenses
        		                     324,080,000    2,024,000     
          change in fair value of redeemable convertible preferred stock warrant liability
        		                              
          maturity of investments
        		                              
          proceeds from issuance of series d redeemable convertible preferred stock, net of issuance costs
        		                              
          payments of deferred offering costs
        		                              
          borrowings of long-term debt
        		                              
          fair value of warrants issued in connection with debt
        		                              
          accrued payroll
        		                           2,440,000 2,175,000 -140,000 
          proceeds from issuance of common stock and exercise of stock options
        		                           864,000 25,000 220,000 
          principal repayment on long term debt
        		                           -834,000   
          proceeds from initial public offering, net of underwriting discounts, commissions and offering expenses
        		                            -826,000 72,779,000 
          changes in assets and liabilities, net of impact of business combination:
        		                              
          inventory
        		                             467,000 
          change in restricted cash
        		                              
          cash acquired through business combination
        		                              
          net increase in cash and cash equivalents
        		                              
          cash and cash equivalents at beginning of year
        		                              
          cash and cash equivalents at end of year
        		                              
          fair value of common stock issued to owners of genome compiler corporation