Tenaya Therapeutics(NASDAQ:TNYA) 
Tenaya Therapeutics, Inc. develops therapeutics for heart failure. It offers cellular regeneration platform, that enables in vivo reprogramming of cardiac fibroblasts into cardio myocytes by delivering proprietary transcription factors; gene therapy platform, that enables the targeted delivery of a ...
Website: http://www.tenayatherapeutics.com
Founded: 2016
CEO: Faraz Ali
Sector: Healthcare
Industry: Biotechnology
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At a glance:
Bull Thesis:
Bear Thesis:
Main Competitors:
Moat:
Income Statements:
Quarterly
Annual
| Unit: USD | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
revenue | ||||||||||||||||||||
yoy | ||||||||||||||||||||
qoq | ||||||||||||||||||||
collaboration revenue | 225,000 | |||||||||||||||||||
operating expenses: | ||||||||||||||||||||
research and development | 14,843,000 | 14,798,000 | 15,363,000 | 17,370,000 | 21,076,000 | 18,688,000 | 20,350,000 | 22,649,000 | 25,055,000 | 22,865,000 | 23,091,000 | 26,477,000 | 25,605,000 | 25,748,000 | 23,758,000 | 20,876,000 | 24,155,000 | 20,953,000 | 12,944,000 | 10,906,000 |
general and administrative | 5,447,000 | 5,977,000 | 5,573,000 | 6,712,000 | 6,462,000 | 5,964,000 | 6,361,000 | 8,174,000 | 8,707,000 | 8,581,000 | 7,829,000 | 8,627,000 | 8,118,000 | 8,802,000 | 7,540,000 | 7,743,000 | 6,999,000 | 5,211,000 | 5,356,000 | 4,331,000 |
total operating expenses | 20,290,000 | 20,775,000 | 20,936,000 | 24,082,000 | 27,538,000 | 24,652,000 | 26,711,000 | 30,823,000 | 33,762,000 | 31,446,000 | 30,920,000 | 35,104,000 | 33,723,000 | 34,550,000 | 31,298,000 | 28,619,000 | 31,154,000 | 26,164,000 | 18,300,000 | 15,237,000 |
income from operations | -20,065,000 | -20,775,000 | -20,936,000 | -24,082,000 | -27,538,000 | -24,652,000 | -26,711,000 | -30,823,000 | -33,762,000 | -31,446,000 | -30,920,000 | -35,104,000 | -33,723,000 | -34,550,000 | -31,298,000 | -28,619,000 | -31,154,000 | -26,164,000 | -18,300,000 | -15,237,000 |
yoy | -27.14% | -15.73% | -21.62% | -21.87% | -18.43% | -21.61% | -13.61% | -12.20% | 0.12% | -8.98% | -1.21% | 22.66% | 8.25% | 32.05% | 71.03% | 87.83% | ||||
qoq | -3.42% | -0.77% | -13.06% | -12.55% | 11.71% | -7.71% | -13.34% | -8.71% | 7.37% | 1.70% | -11.92% | 4.10% | -2.39% | 10.39% | 9.36% | -8.14% | 19.07% | 42.97% | 20.10% | |
operating margin % | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% |
other income, net: | ||||||||||||||||||||
interest income | 793,000 | 575,000 | 658,000 | 815,000 | 635,000 | 812,000 | 1,080,000 | 1,393,000 | 1,452,000 | 1,470,000 | 1,776,000 | 1,837,000 | 1,973,000 | 1,037,000 | 596,000 | 222,000 | 99,000 | 67,000 | 23,000 | 9,000 |
other income | 25,000 | 3,000 | -16,000 | 39,000 | 4,000 | -3,000 | -1,000 | 82,000 | 41,000 | 1,000 | -2,000 | 13,000 | -3,000 | 6,000 | -1,000 | -54,000 | 15,000 | 18,000 | ||
total other income | 793,000 | 600,000 | 661,000 | 799,000 | 674,000 | 816,000 | 1,077,000 | 1,392,000 | 1,534,000 | 1,511,000 | 1,777,000 | 1,835,000 | 1,986,000 | 1,034,000 | 602,000 | 222,000 | 98,000 | 13,000 | 38,000 | 27,000 |
net loss before income tax expense | -19,272,000 | -20,175,000 | -20,275,000 | -23,283,000 | -26,864,000 | -23,836,000 | -25,634,000 | -29,431,000 | -32,228,000 | -29,935,000 | -29,143,000 | -33,269,000 | -31,737,000 | -33,516,000 | -30,696,000 | -28,397,000 | -31,056,000 | -26,151,000 | -18,262,000 | -15,210,000 |
income tax expense | ||||||||||||||||||||
net income | -19,272,000 | -20,175,000 | -20,275,000 | -23,283,000 | -26,864,000 | -23,836,000 | -25,634,000 | -29,431,000 | -32,228,000 | -29,935,000 | -29,143,000 | -33,269,000 | -31,737,000 | -33,516,000 | -30,696,000 | -28,397,000 | -31,056,000 | -26,151,000 | -18,262,000 | |
yoy | -28.26% | -15.36% | -20.91% | -20.89% | -16.64% | -20.37% | -12.04% | -11.54% | 1.55% | -10.68% | -5.06% | 17.16% | 2.19% | 28.16% | 68.09% | |||||
qoq | -4.48% | -0.49% | -12.92% | -13.33% | 12.70% | -7.01% | -12.90% | -8.68% | 7.66% | 2.72% | -12.40% | 4.83% | -5.31% | 9.19% | 8.10% | -8.56% | 18.76% | 43.20% | ||
net income margin % | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | NaN% |
other comprehensive loss | ||||||||||||||||||||
net unrealized loss on marketable securities | -38,000 | 389,000 | -28,000 | |||||||||||||||||
comprehensive loss | -19,272,000 | -20,175,000 | -20,274,000 | -23,274,000 | -26,902,000 | -23,884,000 | -25,491,000 | -29,378,000 | -32,242,000 | -29,780,000 | -29,071,000 | -33,482,000 | -31,479,000 | -33,127,000 | -30,724,000 | -28,505,000 | -31,546,000 | -26,269,000 | -18,285,000 | |
net income per share | -0.09 | -0.11 | -0.12 | -0.14 | -0.24 | -0.27 | -0.3 | -0.34 | -0.4 | -0.4 | -0.39 | -0.45 | -0.43 | -0.58 | -0.74 | -0.69 | -0.75 | 0.65 | -0.68 | -13.26 |
weighted-average shares used for eps calculation | 216,883,164 | 152,971,259 | 163,345,972 | 162,791,579 | 109,869,278 | 84,822,468 | 86,162,841 | 85,706,501 | 80,982,326 | 73,786,126 | 73,924,937 | 73,399,847 | 73,097,889 | 44,823,597 | 41,358,296 | 41,302,157 | 41,267,990 | 17,734,166 | 26,895,716 | 1,147,471 |
other comprehensive loss: | ||||||||||||||||||||
net unrealized gain on marketable securities | 1,000 | 9,000 | -48,000 | 143,000 | 53,000 | -14,000 | 155,000 | 72,000 | -213,000 | 258,000 | ||||||||||
other comprehensive income: | ||||||||||||||||||||
unrealized loss on marketable securities | -108,000 | -490,000 | -118,000 | -23,000 | ||||||||||||||||
change in fair value of convertible preferred stock tranche liability | ||||||||||||||||||||
net loss and comprehensive loss | -15,210,000 |
Balance Sheets:
Quarterly
Annual
| Unit: USD | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
assets | ||||||||||||||||||||
current assets: | ||||||||||||||||||||
cash and cash equivalents | 80,887,000 | 100,547,000 | 56,312,000 | 62,671,000 | 53,772,000 | 4,323,000 | 8,231,000 | 58,134,000 | 59,303,000 | 45,681,000 | 82,153,000 | 75,565,000 | 72,542,000 | 95,272,000 | 34,494,000 | 31,010,000 | 25,970,000 | 38,129,000 | 117,077,000 | 111,886,000 |
accounts receivable | 10,627,000 | |||||||||||||||||||
prepaid expenses and other current assets | 5,048,000 | 5,039,000 | 4,927,000 | 4,208,000 | 6,327,000 | 5,929,000 | 5,861,000 | 5,726,000 | 6,450,000 | 6,940,000 | 5,075,000 | 6,401,000 | 6,815,000 | 7,227,000 | 7,617,000 | 4,777,000 | 3,328,000 | 4,058,000 | 4,357,000 | 1,336,000 |
total current assets | 96,562,000 | 105,586,000 | 61,239,000 | 75,875,000 | 94,485,000 | 67,375,000 | 85,330,000 | 105,029,000 | 128,699,000 | 111,582,000 | 126,828,000 | 138,906,000 | 154,628,000 | 193,754,000 | 157,067,000 | 185,693,000 | 213,782,000 | 255,358,000 | 284,822,000 | 113,222,000 |
property and equipment | 25,960,000 | 27,672,000 | 29,440,000 | 31,285,000 | 33,360,000 | 35,858,000 | 37,753,000 | 39,437,000 | 41,396,000 | 43,277,000 | 45,131,000 | 47,039,000 | 49,352,000 | 51,032,000 | 52,194,000 | 53,013,000 | 49,384,000 | 43,020,000 | 30,891,000 | 24,910,000 |
operating lease right-of-use assets | 8,763,000 | 9,417,000 | 10,057,000 | 10,682,000 | 11,294,000 | 11,890,000 | 12,626,000 | 13,656,000 | 9,177,000 | 9,979,000 | 9,337,000 | 10,133,000 | 10,909,000 | 11,663,000 | 12,399,000 | 13,114,000 | 11,353,000 | 11,685,000 | 12,006,000 | 12,315,000 |
other noncurrent assets | 3,785,000 | 4,246,000 | 4,244,000 | 4,309,000 | 4,813,000 | 4,817,000 | 4,873,000 | 5,063,000 | 5,627,000 | 5,677,000 | 5,734,000 | 5,540,000 | 4,630,000 | 4,793,000 | 4,650,000 | 3,710,000 | 6,579,000 | |||
total assets | 135,070,000 | 146,921,000 | 104,980,000 | 122,151,000 | 143,952,000 | 119,940,000 | 140,582,000 | 163,185,000 | 184,899,000 | 170,515,000 | 193,397,000 | 220,754,000 | 245,341,000 | 278,945,000 | 226,310,000 | 255,929,000 | 281,497,000 | 314,189,000 | 331,794,000 | 156,895,000 |
liabilities and stockholders’ equity | ||||||||||||||||||||
current liabilities: | ||||||||||||||||||||
accounts payable | 1,914,000 | 3,581,000 | 2,843,000 | 3,297,000 | 5,064,000 | 5,162,000 | 5,839,000 | 4,319,000 | 6,659,000 | 5,630,000 | 5,902,000 | 8,484,000 | 7,430,000 | 9,578,000 | 5,312,000 | 5,347,000 | 8,888,000 | 10,721,000 | 6,171,000 | 5,020,000 |
accrued and other current liabilities | 6,030,000 | 8,835,000 | 7,441,000 | 6,523,000 | 6,294,000 | 8,035,000 | 7,327,000 | 9,030,000 | 8,435,000 | 12,784,000 | 10,321,000 | 8,986,000 | 8,145,000 | 10,664,000 | 8,388,000 | 9,498,000 | ||||
contract liabilities, current | 5,722,000 | |||||||||||||||||||
operating lease liabilities, current | 3,115,000 | 3,020,000 | 2,926,000 | 2,834,000 | 2,794,000 | 2,778,000 | 3,011,000 | 3,363,000 | 4,064,000 | 4,319,000 | 3,154,000 | 3,447,000 | 3,730,000 | 4,006,000 | 4,016,000 | 3,896,000 | 2,075,000 | 1,994,000 | 1,914,000 | 1,637,000 |
total current liabilities | 16,781,000 | 15,436,000 | 13,210,000 | 12,654,000 | 14,152,000 | 15,975,000 | 16,177,000 | 16,712,000 | 19,158,000 | 22,733,000 | 19,377,000 | 20,917,000 | 19,305,000 | 24,248,000 | 17,716,000 | 18,741,000 | 19,095,000 | 21,774,000 | 13,692,000 | 9,800,000 |
contract liabilities, noncurrent | 4,680,000 | |||||||||||||||||||
operating lease liabilities, noncurrent | 7,002,000 | 7,810,000 | 8,601,000 | 9,376,000 | 10,117,000 | 10,830,000 | 11,527,000 | 12,210,000 | 7,302,000 | 8,105,000 | 8,890,000 | 9,657,000 | 10,390,000 | 11,093,000 | 12,043,000 | 13,104,000 | 13,093,000 | |||
other noncurrent liabilities | 418,000 | 410,000 | 301,000 | 293,000 | 287,000 | 281,000 | 276,000 | 266,000 | 259,000 | 253,000 | 246,000 | 240,000 | 234,000 | 228,000 | 223,000 | 217,000 | 212,000 | |||
total liabilities | 28,881,000 | 23,656,000 | 22,112,000 | 22,323,000 | 24,556,000 | 27,086,000 | 27,980,000 | 29,188,000 | 26,719,000 | 31,091,000 | 28,513,000 | 30,814,000 | 29,929,000 | 35,569,000 | 29,982,000 | 32,062,000 | 32,400,000 | 35,663,000 | 28,095,000 | 24,696,000 |
commitments and contingencies | ||||||||||||||||||||
stockholders’ equity: | ||||||||||||||||||||
preferred stock, 0.0001 par value... | ||||||||||||||||||||
common stock, 0.0001 par value... | 21,000 | 21,000 | 8,000 | 7,000 | 7,000 | 4,000 | ||||||||||||||
additional paid-in capital | 730,448,000 | 728,252,000 | 667,685,000 | 664,371,000 | 660,665,000 | 607,229,000 | 603,093,000 | 598,997,000 | 593,802,000 | 542,805,000 | 538,485,000 | 534,470,000 | 526,460,000 | 522,945,000 | 442,773,000 | 439,588,000 | 436,313,000 | 434,196,000 | 433,112,000 | 2,596,000 |
accumulated other comprehensive income | -1,000 | -10,000 | 28,000 | |||||||||||||||||
accumulated deficit | -624,280,000 | -605,008,000 | -584,833,000 | -564,558,000 | -541,275,000 | -514,411,000 | -490,575,000 | -464,941,000 | -435,510,000 | -403,282,000 | -373,347,000 | -344,204,000 | -310,935,000 | -279,198,000 | -245,682,000 | -214,986,000 | -186,589,000 | -155,533,000 | -129,382,000 | -111,120,000 |
total stockholders’ equity | 106,189,000 | 123,265,000 | 82,868,000 | 99,828,000 | 119,396,000 | 92,854,000 | 112,602,000 | 133,997,000 | 158,180,000 | 139,424,000 | 164,884,000 | 189,940,000 | 215,412,000 | 243,376,000 | 196,328,000 | 223,867,000 | 249,097,000 | 278,526,000 | 303,699,000 | |
total liabilities and stockholders’ equity | 135,070,000 | 146,921,000 | 104,980,000 | 122,151,000 | 143,952,000 | 119,940,000 | 140,582,000 | 163,185,000 | 184,899,000 | 170,515,000 | 193,397,000 | 220,754,000 | 245,341,000 | 278,945,000 | 226,310,000 | 255,929,000 | 281,497,000 | |||
short-term investments in marketable securities | 8,996,000 | 34,386,000 | 57,123,000 | 71,238,000 | 41,169,000 | 62,946,000 | 58,961,000 | 39,600,000 | 56,940,000 | 75,271,000 | 91,255,000 | |||||||||
common stock | 16,000 | 16,000 | 16,000 | 8,000 | 8,000 | 8,000 | 7,000 | 7,000 | 7,000 | 4,000 | 4,000 | 4,000 | 4,000 | |||||||
accumulated other comprehensive loss | 76,000 | -67,000 | -120,000 | -106,000 | -261,000 | -333,000 | -120,000 | -378,000 | -767,000 | -739,000 | -631,000 | -141,000 | -23,000 | |||||||
long-term investments in marketable securities | 6,367,000 | 19,136,000 | 25,822,000 | 17,703,000 | ||||||||||||||||
investments in marketable securities | 114,956,000 | 149,906,000 | 184,484,000 | 213,171,000 | 163,388,000 | |||||||||||||||
restricted cash, noncurrent | 399,000 | 399,000 | ||||||||||||||||||
accrued expenses and other current liabilities | 8,132,000 | 9,059,000 | 5,607,000 | 3,143,000 | ||||||||||||||||
restricted cash, non-current | 547,000 | 547,000 | 547,000 | |||||||||||||||||
other non-current assets | 3,579,000 | 3,528,000 | 5,901,000 | |||||||||||||||||
liabilities, convertible preferred stock and stockholders’ equity | ||||||||||||||||||||
deferred rent and other lease liabilities, current | ||||||||||||||||||||
deferred rent and other lease liabilities, non-current | ||||||||||||||||||||
operating lease liabilities, non-current | 13,707,000 | 14,307,000 | 14,893,000 | |||||||||||||||||
other non-current liabilities | 182,000 | 96,000 | 3,000 | |||||||||||||||||
convertible preferred stock, 0.0001 par value... | ||||||||||||||||||||
stockholders’ equity | ||||||||||||||||||||
notes receivable from stockholders | -12,000 | -12,000 | ||||||||||||||||||
total liabilities, convertible preferred stock and stockholders’ equity | 314,189,000 | 331,794,000 | ||||||||||||||||||
convertible preferred stock | 240,735,000 | |||||||||||||||||||
liabilities, convertible preferred stock and stockholders’ deficit | ||||||||||||||||||||
stockholders’ deficit: | ||||||||||||||||||||
total stockholders’ deficit | -108,536,000 | |||||||||||||||||||
total liabilities, convertible preferred stock and stockholders’ deficit | 156,895,000 |
Cashflow Statements:
Quarterly
Annual
| Unit: USD | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cash flows from operating activities: | |||||||||||||||||||
net loss | -19,272,000 | -20,175,000 | -20,275,000 | -23,283,000 | -26,864,000 | -23,836,000 | -25,634,000 | -29,431,000 | -32,228,000 | -29,935,000 | -29,143,000 | -33,269,000 | -31,737,000 | -33,516,000 | -30,696,000 | -28,397,000 | -31,056,000 | -26,151,000 | -18,262,000 |
adjustments to reconcile net loss to net cash from operating activities: | |||||||||||||||||||
depreciation and amortization | 1,763,000 | 1,827,000 | 1,864,000 | 2,084,000 | 2,661,000 | 2,089,000 | 2,101,000 | 2,123,000 | 2,155,000 | 2,181,000 | 2,181,000 | 2,195,000 | 2,130,000 | 2,117,000 | 2,087,000 | 1,297,000 | 966,000 | 791,000 | 746,000 |
amortization of premium (discount) on marketable securities | 0 | 111,000 | 269,000 | 31,000 | -240,000 | -12,000 | 142,000 | -74,000 | 1,686,000 | ||||||||||
stock-based compensation | 2,196,000 | 2,745,000 | 2,934,000 | 3,636,000 | 3,731,000 | 3,759,000 | 3,907,000 | 4,611,000 | 4,224,000 | 3,949,000 | 4,015,000 | 3,831,000 | 3,514,000 | 3,187,000 | 3,174,000 | 3,012,000 | 2,094,000 | 1,048,000 | 968,000 |
non-cash operating lease expense | 654,000 | 640,000 | 625,000 | 612,000 | 596,000 | 736,000 | 1,030,000 | 823,000 | 802,000 | 806,000 | 796,000 | 776,000 | 754,000 | 736,000 | 715,000 | 463,000 | 332,000 | 321,000 | 309,000 |
other | 8,000 | 130,000 | 63,000 | 62,000 | 168,000 | 140,000 | 89,000 | 54,000 | 100,000 | 60,000 | 52,000 | 53,000 | 52,000 | ||||||
changes in operating assets and liabilities: | |||||||||||||||||||
accounts receivable | -10,627,000 | ||||||||||||||||||
prepaid expenses and other current assets | -9,000 | -167,000 | -774,000 | 1,948,000 | -460,000 | -169,000 | -112,000 | 691,000 | 447,000 | -1,912,000 | 1,280,000 | 367,000 | 366,000 | 344,000 | -2,840,000 | -1,170,000 | 732,000 | 299,000 | -3,122,000 |
other noncurrent assets | 461,000 | -2,000 | 65,000 | 504,000 | 4,000 | 56,000 | 249,000 | 301,000 | 50,000 | 57,000 | 68,000 | -889,000 | 163,000 | -143,000 | -540,000 | -157,000 | 25,000 | ||
accounts payable | -1,460,000 | 531,000 | -447,000 | -1,135,000 | -379,000 | -701,000 | 1,280,000 | -2,432,000 | 1,272,000 | -305,000 | -2,754,000 | 1,101,000 | -1,324,000 | 3,463,000 | 317,000 | -341,000 | -1,779,000 | 6,082,000 | 1,155,000 |
accrued and other current liabilities | -2,637,000 | 1,126,000 | 918,000 | 391,000 | -1,903,000 | 708,000 | -1,699,000 | 596,000 | -4,350,000 | 2,556,000 | 1,242,000 | 1,120,000 | -2,662,000 | 2,297,000 | 1,340,000 | ||||
contract liabilities | 10,402,000 | ||||||||||||||||||
operating lease liabilities | -713,000 | -697,000 | -683,000 | -701,000 | -697,000 | -930,000 | -1,035,000 | -1,095,000 | -1,058,000 | -1,068,000 | -1,060,000 | -1,016,000 | -979,000 | -960,000 | -941,000 | -673,000 | -533,000 | -520,000 | -207,000 |
net cash from operating activities | -19,234,000 | -13,940,000 | -15,599,000 | -15,613,000 | -23,112,000 | -18,388,000 | -19,836,000 | -23,617,000 | -28,660,000 | -21,924,000 | -23,638,000 | -26,220,000 | -30,290,000 | -22,682,000 | -27,556,000 | -25,430,000 | -28,756,000 | -16,347,000 | -16,657,000 |
capital expenditures | -11,000 | -67,000 | -26,000 | -142,000 | -383,000 | -204,000 | -184,000 | -73,000 | -564,000 | -394,000 | -8,000 | -208,000 | -629,000 | -795,000 | -4,064,000 | -7,176,000 | -8,595,000 | -12,554,000 | -5,008,000 |
free cash flows | -19,245,000 | -14,007,000 | -15,625,000 | -15,755,000 | -23,495,000 | -18,592,000 | -20,020,000 | -23,690,000 | -29,224,000 | -22,318,000 | -23,646,000 | -26,428,000 | -30,919,000 | -23,477,000 | -31,620,000 | -32,606,000 | -37,351,000 | -28,901,000 | -21,665,000 |
cash flows from investing activities: | |||||||||||||||||||
purchases of property and equipment | -11,000 | -67,000 | -26,000 | -142,000 | -383,000 | -204,000 | -184,000 | -73,000 | -564,000 | -394,000 | -8,000 | -208,000 | -629,000 | -795,000 | -4,064,000 | -7,176,000 | -8,595,000 | -12,554,000 | -5,008,000 |
proceeds from sales of marketable securities | 0 | 0 | 0 | 10,958,000 | |||||||||||||||
proceeds from maturities of marketable securities | 0 | 8,886,000 | 25,130,000 | 11,727,000 | 8,321,000 | 20,681,000 | 32,492,000 | 19,717,000 | 1,139,000 | 30,500,000 | 40,484,000 | 34,500,000 | 38,500,000 | 78,700,000 | 59,350,000 | 68,200,000 | |||
net cash (used) provided by investing activities | -11,000 | ||||||||||||||||||
cash flows from financing activities: | |||||||||||||||||||
proceeds from issuance of common stock, pre-funded warrants, and warrants in follow-on offering, net of issuance costs | 56,264,000 | 0 | -544,000 | 49,345,000 | |||||||||||||||
proceeds from at-the-market sales, net of issuance costs | 0 | 0 | -2,000 | 914,000 | 0 | 0 | |||||||||||||
payment of accrued offering costs | -415,000 | 0 | 0 | 0 | -501,000 | ||||||||||||||
net cash (used) provided by financing activities | -415,000 | ||||||||||||||||||
net change in cash, cash equivalents and restricted cash | -19,660,000 | 44,235,000 | -6,359,000 | 8,899,000 | 49,449,000 | -3,908,000 | -49,903,000 | -1,432,000 | 13,622,000 | -36,472,000 | 6,850,000 | 3,044,000 | -22,730,000 | 60,778,000 | 3,484,000 | 5,040,000 | -12,307,000 | -78,948,000 | 5,192,000 |
cash and cash equivalents and restricted cash at beginning of period | 100,966,000 | 0 | 0 | 0 | 4,742,000 | 0 | 0 | 0 | 46,363,000 | 0 | 0 | 0 | 95,671,000 | 0 | 0 | 0 | 38,676,000 | 0 | -1,000 |
cash and cash equivalents and restricted cash at end of period | 81,306,000 | 44,235,000 | -6,359,000 | 8,899,000 | 54,191,000 | -3,908,000 | -49,903,000 | -1,432,000 | 59,985,000 | -36,472,000 | 6,850,000 | 3,044,000 | 72,941,000 | 60,778,000 | 3,484,000 | 5,040,000 | 26,369,000 | -78,948,000 | 5,191,000 |
components of cash, cash equivalents and restricted cash: | |||||||||||||||||||
cash and cash equivalents | 80,887,000 | 44,235,000 | -6,359,000 | 8,899,000 | 53,772,000 | -3,908,000 | -49,903,000 | -1,169,000 | 59,303,000 | -36,472,000 | 6,588,000 | 3,023,000 | 72,542,000 | 60,778,000 | 3,484,000 | 5,040,000 | 25,970,000 | -78,948,000 | 5,191,000 |
restricted cash included in other noncurrent assets | 419,000 | 0 | 0 | 0 | 419,000 | 0 | 0 | -263,000 | 682,000 | 0 | 262,000 | 21,000 | 399,000 | 0 | |||||
cash, cash equivalents and restricted cash | 81,306,000 | 44,235,000 | -6,359,000 | 8,899,000 | 54,191,000 | -3,908,000 | -49,903,000 | -1,432,000 | 59,985,000 | -36,472,000 | 6,850,000 | 3,044,000 | 72,941,000 | 60,778,000 | 3,484,000 | 5,040,000 | 26,369,000 | -78,948,000 | 5,191,000 |
supplemental disclosure of non-cash investing and financing activities: | |||||||||||||||||||
property and equipment included in accounts payable and accrued and other current liabilities | 100,000 | -131,000 | 138,000 | 24,000 | 236,000 | 91,000 | 7,000 | -60,000 | 265,000 | -326,000 | 370,000 | 286,000 | -2,797,000 | ||||||
offering cost included in accounts payable and accrued expenses and other current liabilities | |||||||||||||||||||
other noncurrent liabilities | -14,000 | 6,000 | 5,000 | 2,000 | |||||||||||||||
purchases of marketable securities | -2,011,000 | -50,607,000 | -10,808,000 | -23,643,000 | -15,646,000 | 0 | -15,200,000 | -25,798,000 | -31,739,000 | -43,602,000 | -21,964,000 | -43,171,000 | -50,026,000 | ||||||
net cash from investing activities | -67,000 | 8,860,000 | 24,988,000 | 22,302,000 | 14,103,000 | -30,098,000 | 21,615,000 | -4,489,000 | -14,919,000 | 30,488,000 | 25,085,000 | 8,061,000 | 5,974,000 | 31,034,000 | 30,210,000 | 16,434,000 | -62,580,000 | -168,425,000 | |
proceeds from exercise of stock options and employee stock purchase plan | 45,000 | 24,000 | 370,000 | 31,000 | 570,000 | 8,000 | 371,000 | 0 | 99,000 | 6,000 | |||||||||
proceeds from exercise of warrants | 1,933,000 | ||||||||||||||||||
proceeds from exercise of prefunded warrants | |||||||||||||||||||
net cash from financing activities | 58,242,000 | 380,000 | -476,000 | 50,259,000 | 377,000 | 31,000 | 570,000 | 46,771,000 | 371,000 | 0 | 4,179,000 | -501,000 | 77,486,000 | 6,000 | 260,000 | 15,000 | -21,000 | 190,274,000 | |
issuance of warrant in connection with loan agreement | 0 | ||||||||||||||||||
offering costs related to follow-on offering and at-the market-sales included in accounts payable and accrued expenses and other current liabilities | 546,000 | ||||||||||||||||||
non-cash exercise of stock options | 3,000 | ||||||||||||||||||
proceeds from issuance of common stock and pre-funded warrants in follow-on offering, net of issuance costs | 0 | 0 | 0 | 46,762,000 | |||||||||||||||
proceeds from exercises of pre-funded warrants | 7,000 | 0 | 0 | 1,000 | |||||||||||||||
offering costs related to november 2022 public offering included in accounts payable and accrued and other current liabilities | |||||||||||||||||||
amortization of (discount) premium on marketable securities | -489,000 | -567,000 | |||||||||||||||||
proceeds from issuance of series c convertible preferred stock, net of issuance costs | 0 | 0 | |||||||||||||||||
proceeds from initial public offering, net of issuance costs | -64,000 | ||||||||||||||||||
repurchase of common stock | |||||||||||||||||||
proceeds from repayments on notes receivable from stockholders | 12,000 | 0 | |||||||||||||||||
conversion of convertible preferred stock to common stock upon completion of initial public offering | 19,981,000 | ||||||||||||||||||
amortization of premium on marketable securities | -177,000 | 110,000 | 143,000 | 125,000 | |||||||||||||||
loss on write-offs and disposal of property and equipment | |||||||||||||||||||
offering costs related to initial public offering included in accounts payable and accrued and other current liabilities | |||||||||||||||||||
loss on write-offs of property and equipment | |||||||||||||||||||
payment of deferred offering costs | |||||||||||||||||||
restricted cash, noncurrent | 0 | 399,000 | |||||||||||||||||
deferred offering costs related to initial public offering included in accounts payable and accrued and other current liabilities | |||||||||||||||||||
accrued expenses and other current liabilities | 318,000 | 1,566,000 | 1,762,000 | ||||||||||||||||
proceeds from exercise of stock options | 15,000 | 31,000 | 283,000 | ||||||||||||||||
supplemental disclosure of cash operating activities: | |||||||||||||||||||
cash paid for leases included in operating cash outflows | 1,366,000 | 1,687,000 | 1,593,000 | ||||||||||||||||
supplemental disclosure of non-cash operating activities: | |||||||||||||||||||
lease liability obtained in exchange for right-of-use asset | 0 | 0 | |||||||||||||||||
deferred offering costs related to initial public offering included in accounts payable | |||||||||||||||||||
property and equipment included in accounts payable and accrued expenses and other current liabilities | 5,282,000 | 423,000 | 1,723,000 | ||||||||||||||||
loss on disposal of property and equipment | 57,000 | ||||||||||||||||||
change in fair value of convertible preferred stock tranche liability | |||||||||||||||||||
other non-current assets | -51,000 | -109,000 | |||||||||||||||||
deferred rent and other lease liabilities | |||||||||||||||||||
other non-current liabilities | 86,000 | 93,000 | |||||||||||||||||
proceeds from issuance of series b convertible preferred stock, net of issuance costs | |||||||||||||||||||
repurchases of common stock | 0 | -3,000 | |||||||||||||||||
restricted cash, non-current | 0 | 0 | |||||||||||||||||
settlement of convertible preferred stock tranche liability in connection with the issuance of series b convertible preferred stock | |||||||||||||||||||
offering costs related to series c convertible preferred stock included in accounts payable and accrued expenses and other current liabilities | |||||||||||||||||||
offering costs related to initial public offering included in accounts payable and accrued expenses and other current liabilities | |||||||||||||||||||
offering costs related to series b convertible preferred stock in accrued expenses and other current liabilities | |||||||||||||||||||
deferred offering costs related to initial public offering included in accounts payable and accrued expenses and other current liabilities | |||||||||||||||||||
partial settlement of convertible preferred stock tranche liability in connection with the issuance of series b convertible preferred stock |