7Baggers
Quarterly
Annual
    Unit: USD2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 
      
    		                    
      cash flows from operating activities:
    		                    
      net income
    		-231,793,000 -565,708,000 -62,913,000 -61,203,000 -56,254,000 -60,385,000 -43,473,000 -36,567,000 -21,268,000 -14,717,000 -542,376,000 -19,229,000 -21,385,000 -16,771,000 -21,397,000 -27,099,000 -19,599,000 -24,416,000 -17,488,000 -13,442,000 
      adjustments to reconcile net income to net cash from operating activities:
    		                    
      amortization of discount on short-term investments
    		0 -1,023,000 -2,966,000 2,350,000 -2,919,000 -1,605,000 -402,000 -208,000 1,185,000            
      unrealized foreign exchange (gain) loss
    		                    
      depreciation
    		42,000 37,000 25,000 22,000 20,000 20,000 27,000 30,000 32,000 46,000 90,000 88,000 93,000 99,000 69,000 79,000 81,000 90,000 80,000 35,000 
      stock-based compensation
    		130,761,000 478,784,000 11,096,000 11,015,000 19,371,000 11,088,000 9,507,000 8,753,000 705,000 1,875,000 2,775,000 2,658,000 2,798,000 2,496,000 3,996,000 5,620,000 2,644,000 3,672,000 868,000 578,000 
      acquired in-process research and development expense
    		   0 7,000                
      change in operating assets and liabilities:
    		                    
      prepaid expenses and other current assets
    		3,739,000 -1,931,000 1,850,000                  
      accounts payable
    		-839,000 17,931,000 356,000 1,529,000 -188,000 -3,030,000 3,704,000 -672,000 2,330,000 297,000 308,000 -2,369,000 -1,042,000 -3,480,000 2,759,000 -1,364,000 -1,019,000 2,754,000 -2,082,000 3,491,000 
      accrued liabilities
    		945,000 4,841,000 1,611,000  6,096,000 5,952,000 -2,154,000 5,351,000 -200,000 -8,258,000 730,000 -35,000 5,895,000 -246,000 -832,000  1,134,000 1,175,000 2,102,000 -100,000 
      other current liabilities
    		476,000 704,000 -1,046,000                  
      other non-current liabilities
    		30,000                    
      other long-term assets
    		                    
      accrued compensation
    		4,360,000 2,181,000 -7,588,000 4,042,000 3,066,000 -1,157,000 606,000 1,910,000 -10,000 1,103,000 -3,238,000 4,046,000 648,000 438,000 -3,523,000      
      operating lease right-of-use assets and lease liabilities
    		6,000 -95,000 25,000 48,000 37,000 -160,000 -92,000              
      net cash from operating activities
    		-93,080,000 -66,744,000 -61,168,000 -48,673,000 -30,297,000 -33,002,000 -30,134,000 -19,459,000 -14,897,000 -29,273,000 -13,131,000 5,191,000 -8,555,000 -19,217,000 -19,001,000 -9,179,000 -23,565,000 -19,174,000 -20,669,000 -7,971,000 
      capex
    		21,000 0 -422,000 0 -58,000 -63,000 -4,000 0 -53,000 -20,000 -53,000 0 20,000 -293,000 -361,000 0 0 -151,000 -39,000 0 
      free cash flows
    		-93,059,000 -66,744,000 -61,590,000 -48,673,000 -30,355,000 -33,065,000 -30,138,000 -19,459,000 -14,950,000 -29,293,000 -13,184,000 5,191,000 -8,535,000 -19,510,000 -19,362,000 -9,179,000 -23,565,000 -19,325,000 -20,708,000 -7,971,000 
      cash flows from investing activities:
    		                    
      purchases of property and equipment
    		-71,000 0 -422,000  -58,000 -63,000 -4,000  -53,000 -20,000 -53,000  20,000 -293,000 -361,000      
      purchase of short-term investments
    		   -149,488,000 -167,549,000 -270,013,000 -92,982,000 1,000 -112,858,000 -38,170,000 -169,995,000          
      maturities and sales of short-term investments
    		0 150,808,000 160,532,000 232,984,000 73,999,000 69,997,000 112,857,000 60,569,000 109,425,000            
      payments to akeso for upfront milestone payments and associated direct transaction costs
    		   0    0 0 0 -475,015,000          
      net cash from investing activities
    		-71,000 150,808,000 160,110,000 83,482,000 -108,615,000 -200,079,000 19,871,000 60,568,000 -3,486,000 207,000 -645,063,000 10,000 20,000 -293,000 -361,000 -120,000 4,000 -151,000 -39,000 -50,000 
      cash flows from financing activities:
    		                    
      proceeds from the issuance of common stock via private placements, net of offering costs
    		   -101,000                 
      proceeds from the issuance of common stock under at-the-market offering, net of commissions and offering costs
    		   -4,000                 
      proceeds received related to the exercise of warrants
    		0 1,657,000 5,658,000  0                
      repayment of related party promissory notes
    		        0 0 -24,686,000          
      proceeds received related to employee stock awards and purchase plans
    		2,049,000 565,000 2,019,000                  
      net cash from financing activities
    		33,813,000 2,222,000 7,677,000 -23,612,000 204,142,000 200,212,000 485,000 6,252,000 229,000 -80,000 80,112,000 520,060,000 74,997,000 0 25,187,000 1,261,000 676,000 20,082,000 55,897,000 50,548,000 
      effect of exchange rate changes on cash
    		22,000 61,000 38,000  114,000 12,000 -36,000  -170,000 293,000 444,000  -1,826,000 -605,000 -166,000      
      increase in cash, cash equivalents and restricted cash
    		-59,316,000                    
      cash, cash equivalents and restricted cash at beginning of period
    		0 0 105,187,000 0 0 0 71,425,000              
      cash, cash equivalents and restricted cash at end of period
    		-59,316,000 86,347,000 211,844,000 11,089,000 65,344,000 -32,857,000 61,611,000              
      reconciliation of cash, cash equivalents and restricted cash:
    		                    
      cash and cash equivalents
    		-59,318,000 86,346,000 211,526,000                  
      restricted cash
    		2,000 1,000 318,000                  
      cash, cash equivalents, and restricted cash
    		-59,316,000 86,347,000 211,844,000                  
      supplemental disclosure of cash flow information:
    		                    
      cash paid for interest on related party promissory notes
    		    0 0 1,501,000  2,917,000 3,488,000 1,306,000          
      supplemental disclosure of non-cash investing and financing activities:
    		                    
      offering costs included in accounts payable and accrued expenses
    		                    
      leased assets obtained in exchange for operating lease liabilities
    		                    
      unpaid amounts related to purchase of property, plant and equipment
    		92,000                    
      unrealized foreign exchange gain
    		 -239,000 -224,000    9,000  494,000 -394,000 -470,000  1,905,000 1,329,000 1,037,000 972,000 849,000 224,000 -1,719,000  
      other assets
    		 -2,253,000 -1,419,000                  
      upfront consideration to akeso for second amendment
    		                    
      other long-term liabilities
    		  25,000 25,000 24,000                
      increase in cash and cash equivalents
    		  106,657,000      -18,324,000 -28,853,000 -577,638,000          
      cash flows used in operating activities:
    		                    
      gain on remeasurement of liabilities
    		                    
      non-cash interest expense
    		       82,000 -63,000 111,000 6,123,000 3,450,000 -88,000 743,000 198,000 -284,000 165,000 212,000 103,000  
      unrealized foreign currency gain
    		                    
      reclassification of currency translation gain
    		       0 0 0 -419,000          
      impairment of fixed assets
    		       0 0 0 474,000          
      amortization of intangible assets
    		           217,000 217,000 232,000 248,000 249,000 256,000 257,000 255,000 423,000 
      impairment of intangible assets
    		                    
      loss on disposal of assets
    		                    
      changes in operating assets and liabilities:
    		                    
      accounts receivable
    		       0 3,000 6,000 350,000 -1,412,000 1,227,000 705,000 455,000 932,000 -1,366,000 -590,000 -114,000  
      research and development tax credit receivable
    		   -203,000 260,000 -154,000 632,000 -178,000 3,449,000 47,000 850,000 12,112,000 -1,249,000 -760,000 -1,666,000 5,592,000 -3,753,000 -4,193,000 -3,661,000 -884,000 
      deferred revenue and other income
    		           276,000 -3,422,000 -1,474,000 -2,658,000      
      accrued liabilities and other current liabilities
    		                    
      cash flows used in investing activities:
    		                    
      purchase of property and equipment
    		                 -151,000 -39,000  
      proceeds from sale of property, plant and equipment
    		                    
      proceeds from the issuance of common stock for rights offering
    		       0 0 0 104,686,000          
      transaction costs from the issuance of common stock for rights offering
    		                    
      net receipts related to the exercise of warrants
    		                    
      proceeds received related to employee stock purchase plan and exercise of stock options
    		                    
      proceeds from related party promissory notes
    		           520,000,000 0   0     
      re-payment of related party promissory notes
    		                    
      payments of related party promissory notes issuance costs
    		                    
      effect of exchange rates on cash and cash equivalents
    		                 435,000 588,000 2,620,000 
      cash paid for interest on related party promissory note
    		               82,000 -82,000    
      cash paid for income taxes
    		       0 0        0    
      debt issuance costs in accrued expenses
    		                  38,000  
      consideration for the issuance of common stock for rights offering used to satisfy a portion of a related party promissory note
    		       0 0 0 395,314,000          
      deferred transaction costs included in other non-current assets
    		                    
      issuance of common stock pursuant to the akeso license agreement
    		       0 0 0 45,900,000          
      gain on disposal of assets
    		        11,000            
      prepaid expenses
    		    -181,000 3,545,000 -2,792,000 2,640,000 1,011,000 -4,896,000 331,000 101,000 3,775,000 -1,451,000 2,682,000 1,280,000 -2,903,000 2,330,000 1,638,000 -1,878,000 
      other current and long-term assets
    		    -151,000 -275,000 2,531,000 -43,000 -2,455,000 -1,431,000 508,000          
      proceeds from sale of property and equipment
    		                    
      proceeds from the issuance of common stock for rights offering, net of offering costs
    		                    
      lease assets obtained in exchange for operating lease liabilities
    		    0 0 4,216,000  0        0    
      unrealized foreign exchange
    		                    
      proceeds from sale of property. plant and equipment
    		       0 0            
      transaction costs related to the issuance of common stock for rights offering
    		        0 -80,000 -539,000          
      proceeds from the issuance of common stock via private placement
    		                    
      proceeds received related to employee stock awards
    		     111,000 485,000  229,000 0 651,000  108,000 0 187,000      
      decrease in cash and cash equivalents
    		     -32,857,000 -9,814,000              
      in-process research and development expense
    		       0 0 0 520,915,000          
      other long- term liabilities
    		      1,763,000              
      transaction costs included in accrued expenses
    		          80,000     0 28,000    
      unrealized foreign currency (gain) loss
    		                    
      amortization of operating right-of-use assets
    		       575,000 567,000 425,000 285,000 291,000 402,000 260,000 298,000 343,000 295,000    
      operating lease liabilities
    		       -692,000 -688,000 -464,000 -367,000 -208,000 -297,000 -297,000 -297,000 -325,000 -292,000    
      supplemental disclosure of cash flow information
    		                    
      cash at beginning of the period
    		        0 0 648,607,000  0 0 71,791,000      
      cash and cash equivalents at end of the period
    		        -18,324,000 -28,853,000 70,969,000       1,192,000 102,194,000  
      unrealized foreign exchange loss
    		                    
      other adjustments
    		                    
      proceeds from the issuance of common stock
    		                    
      transaction costs from the issuance of common stock
    		                    
      proceeds from exercise of share options
    		                   596,000 
      effect of exchange rates on cash and restricted cash
    		                    
      cash at beginning of period
    		                    
      other current assets
    		            1,941,000 -1,013,000 -370,000  -277,000 -354,000 549,000 270,000 
      payment of related party promissory notes issuance costs
    		                    
      proceeds from the issuance of common stock for rights-offering
    		                    
      transaction costs related to the issuance of common stock for rights-offering
    		                    
      increase in cash
    		             -20,115,000 5,659,000 -8,457,000     
      cash at end of the period
    		             -20,115,000 77,450,000      
      united kingdom
    		                    
      united states
    		                    
      proceeds from related party promissory note
    		              25,000,000   55,000,000 55,000,000  
      promissory note issuance costs in accrued expenses
    		                    
      gain on recognition of contingent consideration payable
    		                    
      accrued liabilities and accrued compensation
    		                    
      effect of exchange rates on cash
    		                    
      cash at end of period
    		                    
      cash paid (received) for income taxes
    		                    
      intangible asset
    		                    
      option over non-financial assets
    		                    
      loss on disposal of asset
    		                    
      deferred revenue
    		                    
      proceeds from issuance of common stock from rights offering
    		                    
      transaction costs on issuance of common stock from rights offering
    		                -54,000    
      payments of debt issuance costs
    		                0    
      proceeds from exercise of stock options
    		                730,000 241,000 897,000  
      revenue by category:
    		                    
      licensing agreements
    		                    
      cash flows from operating activities
    		                    
      deferred revenue and income
    		                 -354,000 -1,200,000  
      cash flows from investing activities
    		                    
      purchase of intangible assets
    		                    
      cash flows from financing activities
    		                    
      proceeds from issue of common stock from rights offering
    		                    
      repayment of related party promissory note
    		                    
      increase / (decrease) in cash and cash equivalents
    		                 1,192,000 35,777,000  
      cash and cash equivalents at beginning of the period
    		                 0 66,417,000  
      depreciation of operating right-of-use assets
    		                  152,000  
      lease liabilities
    		                  -152,000 -118,000 
      (gain) loss on recognition of contingent consideration payable
    		                    
      depreciation of operating lease right-of-use assets
    		                    
      impairment of goodwill and intangible assets
    		                    
      deferred income taxes
    		                    
      accounts and other receivables
    		                    
      contingent consideration paid
    		                    
      other liabilities
    		                    
      cash and cash equivalents at beginning of the period / year
    		                    
      cash and cash equivalents at end of the period / year
    		                    
      (gain)/loss on recognition of contingent consideration payable
    		                    
      other (income)/expense
    		                    
      deferred income
    		                    
      investing activities
    		                    
      purchase of property, plant and equipment
    		                    
      financing activities
    		                    
      proceeds from issue of share capital
    		                    
      transaction costs on share capital issued
    		                    
      (decrease) / increase in cash and cash equivalents
    		                    
      cash and cash equivalents at beginning of the year
    		                    
      cash and cash equivalents at end of the year
    		                    
    The information provided in this report is taken from www.sec.gov and many other data providers. While we have conducted our best efforts to ensure that the parsed data is accurate, we cannot guarantee its accuracy. Please use caution and understand that any consequences of its use are your own responsibility.