7Baggers

Seagen Quarterly Income Statements Chart

Quarterly
 | 
Annual
 
 Revenue  
 Gross Profit  
 Operating Profit  
 Net Income  
20170630 20170930 20171231 20180331 20180630 20180930 20181231 20190331 20190630 20190930 20191231 20210930 20211231 20220331 20220630 20220930 20221231 20230331 20230630 20230930 -297.96-162.73-27.5107.73242.96378.19513.42648.65Milllion

Seagen Quarterly Income Statements Table

Quarterly
 | 
Annual
 
Unit: USD2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 2014-06-30 2014-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31 2010-12-31 2010-09-30 2010-06-30 2010-03-31 2009-12-31 2009-09-30 2009-06-30 2009-03-31 2008-12-31 2008-09-30 2008-06-30 2008-03-31 2007-12-31 2007-09-30 2007-06-30 2007-03-31 2006-12-31 2006-09-30 2006-06-30 2006-03-31 2005-12-31 2005-09-30 2005-06-30 2005-03-31 2004-12-31 2004-09-30 2004-06-30 2004-03-31 2003-12-31 2003-09-30 2003-06-30 2003-03-31 2002-12-31 2002-09-30 2002-06-30 2002-03-31 2001-09-30 2001-06-30 
                                                                                     
  revenues:                                                                                   
  net product sales570,729,000 543,974,000 468,639,000 463,627,000 428,089,000 431,714,000 383,086,000 369,181,000 366,459,000 166,414,000 167,582,000 158,980,000 135,001,000 132,127,000 126,976,000 122,443,000 95,357,000 83,721,000 79,177,000 74,343,000 70,321,000 70,785,000 70,117,000 66,216,000 58,648,000 63,012,000 59,059,000 55,095,000 48,886,000 46,491,000 48,209,000 44,782,000 38,716,000 38,524,000 36,485,000 35,736,000 33,920,000 35,355,000 33,658,000 34,691,000 34,496,000 33,194,000 10,047,000                                         
  royalty revenues63,561,000 51,189,000 30,178,000 53,360,000 43,904,000 39,109,000 28,181,000 45,981,000 41,028,000 72,273,000 27,261,000 23,337,000 15,620,000 24,553,000 22,662,000 20,551,000 15,674,000 20,031,000 16,670,000 12,375,000 16,980,000 13,712,000 12,224,000 9,188,000 32,331,000 12,613,000 9,702,000 7,615,000 11,050,000 11,854,000 8,143,000 7,334,000 12,673,000 6,629,000 5,250,000 3,540,000 2,399,000 2,129,000 1,698,000 1,238,000                                            
  collaboration and license agreement revenues14,360,000 8,669,000 20,902,000 11,163,000 38,307,000 26,679,000 15,193,000 14,689,000 16,573,000 51,117,000 18,420,000 36,130,000 44,578,000 17,833,000 19,786,000 27,179,000 29,559,000 25,853,000 39,444,000 21,505,000 21,830,000 20,778,000 23,974,000 19,998,000 20,176,000 17,852,000 15,311,000 14,386,000 22,221,000 15,981,000 19,501,000 16,192,000 16,882,000 22,256,000 29,234,000 34,282,000 21,009,000 26,428,000 14,476,000 12,894,000 13,749,000 15,693,000 10,619,000                                         
  total revenues648,650,000 603,832,000 519,719,000 528,150,000 510,300,000 497,502,000 426,460,000 429,851,000 424,060,000 289,804,000 213,263,000 218,447,000 195,199,000 174,513,000 169,424,000 170,173,000 140,590,000 129,605,000 135,291,000 108,223,000 109,131,000 105,275,000 106,315,000 95,402,000 111,155,000 93,477,000 84,072,000 77,096,000 82,157,000 74,326,000 75,853,000 68,308,000 68,271,000 67,409,000 70,969,000 73,558,000 57,328,000 63,912,000 49,832,000 48,823,000 48,245,000 48,887,000 20,666,000                           1,696,000 1,491,000 1,542,000 1,972,000 1,329,587 1,525,377 1,504,593 710,443 634,285 404,706 375,405 269,272 70,331 34,584 
  yoy27.11% 21.37% 21.87% 22.87% 20.34% 71.67% 99.97% 96.78% 117.24% 66.06% 25.88% 28.37% 38.84% 34.65% 25.23% 57.24% 28.83% 23.11% 27.25% 13.44% -1.82% 12.62% 26.46% 23.74% 35.30% 25.77% 10.84% 12.87% 20.34% 10.26% 6.88% -7.14% 19.09% 5.47% 42.42% 50.66% 18.83% 30.73% 141.13%                               27.56% -2.25% 2.49% 177.57% 109.62% 276.91% 300.79% 163.84% 801.86% 1070.21%     
  qoq7.42% 16.18% -1.60% 3.50% 2.57% 16.66% -0.79% 1.37% 46.33% 35.89% -2.37% 11.91% 11.85% 3.00% -0.44% 21.04% 8.48% -4.20% 25.01% -0.83% 3.66% -0.98% 11.44% -14.17% 18.91% 11.19% 9.05% -6.16% 10.54% -2.01% 11.05% 0.05% 1.28% -5.02% -3.52% 28.31% -10.30% 28.25% 2.07% 1.20% -1.31% 136.56%                            13.75% -3.31% -21.81% 48.32% -12.84% 1.38% 111.78% 12.01% 56.73% 7.81% 39.41% 282.86% 103.36%  
  costs and expenses:                                                                                   
  cost of sales165,254,000 180,753,000 111,776,000 108,210,000 108,122,000 106,100,000 87,626,000 86,690,000 82,650,000 9,639,000 8,723,000 8,609,000 7,911,000 30,222,000 12,348,000 13,157,000 10,358,000 10,213,000 9,019,000 8,055,000 7,481,000 7,896,000 7,427,000 6,901,000 5,944,000 6,701,000 6,625,000 5,940,000 5,210,000 5,036,000 4,725,000 4,088,000 3,664,000 3,751,000 3,528,000 3,311,000 3,169,000 2,738,000 2,742,000 2,995,000 3,071,000 2,391,000 724,000                                         
  gross profit483,396,000 423,079,000 407,943,000 419,940,000 402,178,000 391,402,000 338,834,000 343,161,000 341,410,000 280,165,000 204,540,000 209,838,000 187,288,000 144,291,000 157,076,000 157,016,000 130,232,000 119,392,000 126,272,000 100,168,000 101,650,000 97,379,000 98,888,000 88,501,000 105,211,000 86,776,000 77,447,000 71,156,000 76,947,000 69,290,000 71,128,000 64,220,000 64,607,000 63,658,000 67,441,000 70,247,000 54,159,000 61,174,000 47,090,000 45,828,000 45,174,000 46,496,000 19,942,000                                         
  yoy20.19% 8.09% 20.40% 22.37% 17.80% 39.70% 65.66% 63.54% 82.29% 94.17% 30.22% 33.64% 43.81% 20.85% 24.39% 56.75% 28.12% 22.61% 27.69% 13.18% -3.38% 12.22% 27.68% 24.38% 36.73% 25.24% 8.88% 10.80% 19.10% 8.85% 5.47% -8.58% 19.29% 4.06% 43.22% 53.28% 19.89% 31.57% 136.13%                                             
  qoq14.26% 3.71% -2.86% 4.42% 2.75% 15.51% -1.26% 0.51% 21.86% 36.97% -2.52% 12.04% 29.80% -8.14% 0.04% 20.57% 9.08% -5.45% 26.06% -1.46% 4.39% -1.53% 11.74% -15.88% 21.24% 12.05% 8.84% -7.53% 11.05% -2.58% 10.76% -0.60% 1.49% -5.61% -3.99% 29.71% -11.47% 29.91% 2.75% 1.45% -2.84% 133.16%                                          
  gross margin %74.52% 70.07% 78.49% 79.51% 78.81% 78.67% 79.45% 79.83% 80.51% 96.67% 95.91% 96.06% 95.95% 82.68% 92.71% 92.27% 92.63% 92.12% 93.33% 92.56% 93.14% 92.50% 93.01% 92.77% 94.65% 92.83% 92.12% 92.30% 93.66% 93.22% 93.77% 94.02% 94.63% 94.44% 95.03% 95.50% 94.47% 95.72% 94.50% 93.87% 93.63% 95.11% 96.50%                           0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 
  research and development449,047,000 399,868,000 356,015,000 357,843,000 384,605,000 304,254,000 297,659,000 304,294,000 459,092,000 201,061,000 196,119,000 163,929,000 158,265,000 149,772,000 140,175,000 122,860,000 152,502,000 110,504,000 113,606,000 114,406,000 118,184,000 108,172,000 92,711,000 85,554,000 92,871,000 74,607,000 70,790,000 85,737,000 63,395,000 64,043,000 58,510,000 53,694,000 54,496,000 50,772,000 67,847,000 52,273,000 47,735,000 47,663,000 41,392,000 42,755,000 38,487,000 40,239,000 41,080,000 49,643,000 32,434,000 32,520,000 44,287,000 39,287,000 30,316,000 28,918,000 28,263,000 28,712,000 33,246,000 37,582,000 27,711,000 23,499,000 22,152,000 20,109,000 17,735,000 15,179,000 11,805,000 11,081,000 9,797,000 10,007,000 9,251,000 8,537,000 7,806,000 9,365,000 8,975,000 10,993,000 9,578,000 9,014,000 7,572,000 5,119,694 5,479,212 5,633,662 5,527,432 5,356,063 4,296,664 5,314,607 4,852,896 5,093,631 3,519,105 
  selling, general and administrative265,687,000 243,932,000 236,441,000 216,101,000 210,378,000 220,259,000 174,225,000 210,937,000 180,281,000 115,229,000 96,101,000 82,331,000 80,271,000 79,467,000 57,155,000 58,292,000 66,182,000 48,450,000 39,667,000 40,712,000 38,404,000 41,377,000 34,841,000 33,282,000 29,747,000 33,635,000 29,684,000 30,343,000 32,121,000 29,435,000 25,342,000 25,525,000 24,018,000 25,481,000 21,451,000 23,536,000 21,886,000 23,411,000 18,842,000 19,862,000 22,185,000 24,954,000 19,795,000                                         
  total costs and expenses879,988,000 824,553,000 704,232,000 682,154,000 703,105,000 630,613,000 559,510,000 601,921,000 722,023,000 328,218,000 303,047,000 257,157,000 248,836,000 264,824,000 214,998,000 200,457,000 234,419,000 174,617,000 167,488,000 167,497,000 168,449,000 161,124,000 138,727,000 128,844,000 132,177,000 118,621,000 110,572,000 124,659,000 103,900,000 102,050,000 91,478,000 85,951,000 84,642,000 83,090,000 94,753,000 80,567,000 73,715,000 74,620,000 63,589,000 66,114,000 63,743,000 67,584,000 61,599,000                                         
  income from operations-231,338,000 -220,721,000 -184,513,000 -154,004,000 -192,805,000 -133,111,000 -133,050,000 -172,070,000 -297,963,000 -38,414,000 -89,784,000 -38,710,000 -53,637,000 -90,311,000 -45,574,000 -30,284,000 -93,829,000 -45,012,000 -32,197,000 -59,274,000 -59,318,000 -55,849,000 -32,412,000 -33,442,000 -21,022,000 -25,144,000 -26,500,000 -47,563,000 -21,743,000 -27,724,000 -15,625,000 -17,643,000 -16,371,000 -15,681,000 -23,784,000 -7,009,000 -16,387,000 -10,708,000 -13,757,000 -17,291,000 -15,498,000 -18,697,000 -40,933,000 -51,786,000 -32,976,000 -34,896,000 -35,334,000 -8,876,000 10,908,000 -12,701,000 -20,573,000 -23,323,000 -28,260,000 -31,876,000 -23,319,000 -17,589,000 -19,002,000 -16,579,000 -16,395,000 -12,382,000 -10,289,000 -11,244,000 -9,975,000 -9,569,000 -9,417,000 -7,997,000 -6,838,000 -9,022,000 -8,214,000 -11,186,000 -9,882,000 -9,392,000 -7,208,000 -5,733,501 -5,484,452 -5,745,840 -6,299,207       
  yoy19.99% 65.82% 38.68% -10.50% -35.29% 246.52% 48.19% 344.51% 455.52% -57.46% 97.01% 27.82% -42.84% 100.64% 41.55% -48.91% 58.18% -19.40% -0.66% 77.24% 182.17% 122.12% 22.31% -29.69% -3.32% -9.31% 69.60% 169.59% 32.81% 76.80% -34.30% 151.72% -0.10% 46.44% 72.89% -59.46% 5.74% -42.73% -66.39% -66.61% -53.00% -46.42% 15.85% 483.44% -402.31% 174.75% 71.75% -61.94% -138.60% -60.15% -11.78% 32.60% 48.72% 92.27% 42.23% 42.05% 84.68% 47.45% 64.36% 29.40% 9.26% 40.60% 45.88% 6.06% 14.65% -28.51% -30.80% -3.94% 13.96% 95.10% 80.18% 63.46% 14.43%           
  qoq4.81% 19.62% 19.81% -20.12% 44.85% 0.05% -22.68% -42.25% 675.66% -57.22% 131.94% -27.83% -40.61% 98.16% 50.49% -67.72% 108.45% 39.80% -45.68% -0.07% 6.21% 72.31% -3.08% 59.08% -16.39% -5.12% -44.28% 118.75% -21.57% 77.43% -11.44% 7.77% 4.40% -34.07% 239.34% -57.23% 53.04% -22.16% -20.44% 11.57% -17.11% -54.32% -20.96% 57.04% -5.50% -1.24% 298.08% -181.37% -185.88% -38.26% -11.79% -17.47% -11.34% 36.70% 32.58% -7.44% 14.61% 1.12% 32.41% 20.34% -8.49% 12.72% 4.24% 1.61% 17.76% 16.95% -24.21% 9.84% -26.57% 13.20% 5.22% 30.30% 25.72% 4.54% -4.55% -8.78%        
  operating margin %-35.66% -36.55% -35.50% -29.16% -37.78% -26.76% -31.20% -40.03% -70.26% -13.26% -42.10% -17.72% -27.48% -51.75% -26.90% -17.80% -66.74% -34.73% -23.80% -54.77% -54.35% -53.05% -30.49% -35.05% -18.91% -26.90% -31.52% -61.69% -26.47% -37.30% -20.60% -25.83% -23.98% -23.26% -33.51% -9.53% -28.58% -16.75% -27.61% -35.42% -32.12% -38.25% -198.07%                           -659.55% -662.78% -609.08% -365.52% -431.22% -359.55% -381.89% -886.66% 0%      
  investment and other income14,978,000 12,084,000 14,400,000 10,176,000 4,278,000   -4,904,000 5,228,000 64,244,000 -2,129,000 -40,528,000 40,308,000 -53,147,000 -21,872,000 106,557,000  -47,546,000 82,218,000 2,914,000 -672,000     288,000 62,000 61,000 53,000 1,040,000 59,000 53,000 70,000 10,000 98,000 110,000 123,000 112,000 105,000 55,000 3,200,000                                           
  income before income taxes-216,360,000 -208,637,000 -170,113,000 -143,828,000 -188,527,000 -134,720,000 -135,240,000 -176,974,000 -292,735,000                                                                           
  benefit for income taxes-571,000                                                                                   
  net income-215,789,000 -211,528,000 -174,737,000 -148,171,000 -190,816,000 -134,827,000 -136,494,000 -174,628,000 -293,847,000 25,830,000 -91,913,000 -79,238,000 -13,329,000 -119,805,000 -67,446,000 76,273,000 -111,715,000 -59,201,000 50,021,000 -56,360,000 -59,990,000 -55,138,000 -31,752,000 -32,743,000 -20,478,000 -24,856,000 -26,438,000 -47,502,000 -21,690,000 -26,684,000 -15,566,000 -17,590,000 -16,301,000 -15,671,000 -23,686,000 -6,899,000 -16,264,000 -10,596,000 -13,652,000 -17,236,000 -12,298,000 -27,165,000 -40,685,000 -51,506,000 -32,674,000 -34,546,000 -34,856,000 -8,323,000 11,460,000 -12,117,000 -19,827,000 -22,471,000 -27,268,000 -30,597,000 -21,764,000 -16,028,000 -17,112,000 -14,941,000 -14,613,000 -10,550,000 -8,828,000 -10,020,000 -8,649,000 -8,643,000 -8,703,000 -7,349,000 -6,171,000 -8,360,000 -7,553,000 -10,570,000 -9,368,000 -8,836,000 -6,665,000 -5,436,168 -5,183,399 -5,504,827 -5,961,606       
  yoy13.09% 56.89% 28.02% -15.15% -35.06% -621.98% 48.50% 120.38% 2104.57% -121.56% 36.28% -203.89% -88.07% 102.37% -234.84% -235.33% 86.22% 7.37% -257.54% 72.13% 192.95% 121.83% 20.10% -31.07% -5.59% -6.85% 69.84% 170.05% 33.06% 70.28% -34.28% 154.96% 0.23% 47.90% 73.50% -59.97% 32.25% -60.99% -66.44% -66.54% -62.36% -21.37% 16.72% 518.84% -385.11% 185.10% 75.80% -62.96% -142.03% -60.40% -8.90% 40.20% 59.35% 104.79% 48.94% 51.92% 93.84% 49.11% 68.96% 22.06% 1.44% 36.35% 40.16% 3.39% 15.23% -30.47% -34.13% -5.39% 13.32% 94.44% 80.73% 60.51% 11.80%           
  qoq2.01% 21.06% 17.93% -22.35% 41.53% -1.22% -21.84% -40.57% -1237.62% -128.10% 16.00% 494.48% -88.87% 77.63% -188.43% -168.27% 88.70% -218.35% -188.75% -6.05% 8.80% 73.65% -3.03% 59.89% -17.61% -5.98% -44.34% 119.00% -18.72% 71.42% -11.51% 7.91% 4.02% -33.84% 243.33% -57.58% 53.49% -22.38% -20.79% 40.15% -54.73% -33.23% -21.01% 57.64% -5.42% -0.89% 318.79% -172.63% -194.58% -38.89% -11.77% -17.59% -10.88% 40.59% 35.79% -6.33% 14.53% 2.24% 38.51% 19.51% -11.90% 15.85% 0.07% -0.69% 18.42% 19.09% -26.18% 10.68% -28.54% 12.83% 6.02% 32.57% 22.60% 4.88% -5.84% -7.66%        
  net income margin %-33.27% -35.03% -33.62% -28.05% -37.39% -27.10% -32.01% -40.63% -69.29% 8.91% -43.10% -36.27% -6.83% -68.65% -39.81% 44.82% -79.46% -45.68% 36.97% -52.08% -54.97% -52.38% -29.87% -34.32% -18.42% -26.59% -31.45% -61.61% -26.40% -35.90% -20.52% -25.75% -23.88% -23.25% -33.38% -9.38% -28.37% -16.58% -27.40% -35.30% -25.49% -55.57% -196.87%                           -623.23% -628.30% -573.02% -337.98% -408.86% -339.81% -365.87% -839.14% 0%      
  net income per share-1.15 -1.13 -0.93 -0.79 -1.03 -0.73 -0.74 -0.95 -1.61 0.17 -0.55 -0.49 -0.08 -0.75 -0.42 0.48 -0.73 -0.42 0.35 -0.39 -0.42 -0.39 -0.23 -0.23 -0.15 -0.17 -0.21 -0.38 -0.17 -0.22 -0.13 -0.14 -0.13 -0.12 -0.19 -0.06 -0.14 -0.09 -0.12 -0.15 -0.11 -0.23 -0.35 -0.45 -0.3 -0.35 -0.34 -0.08 0.11 -0.11 -0.21 -0.26 -0.33 -0.39 -0.27 -0.2 -0.22 -0.23 -0.22 -0.18 -0.16 -0.2 -0.17 -0.17 -0.21 -0.18 -0.15 -0.2 -0.18 -0.24 -0.4 -0.89 -0.24           
  shares used in computation of per share amounts - basic and diluted188,135 187,559 186,889 46,049.75 184,792 184,145 183,647   2,070 168,109  160,657                                                                       
  comprehensive loss:                                                                                   
  other comprehensive income:                                                                                   
  unrealized gain on securities available-for-sale, net of tax97 172 1,370 -1,118 -875  -861 -2.5 37 74.25 -177 252 222       4,435                                                                
  foreign currency translation gain189 228 -1,172 1,572 3,363 2,819 106 67 -6 20 -7 18 34 -40 13 -15  -5 14 -2 -3 -7                                                           
  total other comprehensive income286 400 198 515 2,488 83  356 31 -73 -184 270 256 265 -131 90 19    3,980 -278 -153   8.75 -6                                                         
  comprehensive loss-215,503 -211,128 -174,539 -115,080.25 -188,328 -134,744 -137,249   25,757 -92,097  -13,073    -111,696   -51,921 -56,010 -55,416 -31,905 -32,485 -19,685 -25,545 -26,444 -47,479 -21,672 -27,214 -15,821 -16,843 -16,281 -15,729 -23,639 -6,926 -16,274 -10,572 -13,602 -17,238 -12,353                                           
  benefit from income taxes 2,891,000 4,624,000 912,500 2,289,000 107,000 1,254,000 278,000 1,112,000                                                                           
  investment and other income      -1,609,000 -2,190,000                                                                             
  unrealized loss on securities available-for-sale, net of tax     -2,736                                                                              
  other comprehensive loss:                                                                                   
  total other comprehensive loss      -755                                                                             
  shares used in computation of per share amounts - basic       352 182,303   161,436  39,199.75 159,304 158,381                                                                    
  shares used in computation of per share amounts - diluted       352 182,303   161,436  39,199.75 159,304 163,382                                                                    
  comprehensive income:                                                                                   
  comprehensive income       -174,272 -293,816   -78,968  -25,727.5 -67,577 76,363  -12,067.25 59,662                                                                 
  cost of royalty revenues         2,289,000 2,104,000 2,288,000 2,389,000 5,363,000 5,320,000 6,148,000 5,377,000 5,450,000 5,196,000 4,324,000 4,380,000 3,679,000 3,748,000 3,107,000 3,615,000 3,678,000 3,473,000 2,639,000 3,174,000 3,536,000 2,901,000 2,644,000 2,464,000 3,086,000 1,927,000 1,447,000 925,000 808,000 613,000 502,000                                            
  unrealized gain on securities available-for-sale, net of tax of 0, 5,915, 0, and 11,087, respectively             -3 -144                                                                     
  unrealized gain on securities available for sale, net of tax               105 27    3,982                                                               
  revenues                                                                                   
  costs and expenses                                                                                   
  investment and other loss                -17,886,000                                                                   
  shares used in computation of per share amounts—basic and diluted                152,049                                                                   
  foreign currency translation loss                -8         -3 -9                                                         
  shares used in computation of net income per share—basic                 35,719 143,357                                                                 
  shares used in computation of net income per share—diluted                 35,719 148,068                                                                 
  unrealized gain on securities available-for-sale, net of tax of 5,915, 0, 11,087, and 0, respectively                 4,511 9,627                                                                 
  shares used in computation of net income per share—basic and diluted                   142,802 142,458 377 140,928 140,283 139,890 3,491 127,667 125,064 124,312 174 123,591 123,209 122,896 30,315 121,990 121,317 120,455 29,340.25 118,471                                             
  investment income                     475,750 660,000 699,000 544,000                 -8,468,000 248,000 280,000 302,000 350,000 478,000 553,000 552,000 584,000 746,000 852,000 992,000 1,279,000 1,555,000 1,561,000 1,890,000 1,638,000 1,782,000 1,832,000 1,461,000 1,224,000 1,326,000 926,000 714,000 648,000 667,000 662,000 661,000 616,000 514,000 556,000 543,000 297,333 301,053 241,013 337,601 416,903 485,941 555,679 576,627 800,372 886,068 
  unrealized gain on securities available for sale                     -275 -146 252 785 11              -55                                           
  other comprehensive gain —unrealized gain on securities available for sale                           23                                                        
  other comprehensive gain—unrealized gain on securities available for sale                            18 -530 -255 747 20 -58 47   24 50                                             
  other comprehensive loss—unrealized loss on securities available for sale                                   -27 -10                                               
  shares used in computation of net income per share - basic and diluted                                       117,252 116,348                     11,965.5 50,997 50,077 42,418                   
  other comprehensive loss - unrealized gain on securities available for sale                                       -2                                            
  weighted-average shares used for eps calculation                                          114,727    101,221                            30,708,938 30,618,987 30,549,829 30,138,023 30,395,760 30,184,006 29,508,376 28,781,416 28,625,420 
  revenue from collaboration and license agreements                                           13,054,000                                        
  operating expenses                                                                                   
  general and administrative                                           15,197,000 12,713,000 10,522,000 7,038,000 6,467,000 5,231,000 5,552,000 3,956,000 4,019,000 4,156,000 4,362,000 3,687,000 4,094,000 3,935,000 4,306,000 3,297,000 2,814,000 2,820,000 2,746,000 2,619,000 2,402,000 2,307,000 1,779,000 1,664,000 1,857,000 1,845,000 1,809,000 1,692,000 1,387,000 1,455,000 1,602,231 1,191,964 1,125,978 1,137,827 984,718 1,093,313 1,054,793 1,105,412 787,105 832,179 
  total operating expenses                                           64,840,000 45,147,000 43,042,000 51,325,000 45,754,000 35,547,000 34,470,000 32,219,000 32,731,000 37,402,000 41,944,000 31,398,000 27,593,000 26,087,000 24,415,000 21,032,000 17,993,000 14,625,000 13,827,000 12,416,000 12,409,000 11,558,000 10,316,000 9,470,000 11,222,000 10,820,000 12,882,000 11,373,000 10,934,000 9,180,000 7,063,088 7,009,829 7,250,433 7,009,650 6,865,569 5,978,783 7,197,169 6,837,835 7,106,406 6,030,995 
  revenues from collaboration and license agreements                                            12,171,000 8,146,000 15,991,000 36,878,000 46,455,000 21,769,000 11,646,000 9,408,000 9,142,000 10,068,000 8,079,000 10,004,000 7,085,000 7,836,000 4,637,000 5,611,000 4,336,000                       
  shares used in computation of net income per share – basic and diluted                                                 21,942.75 93,460 86,200 83,545 19,592.25 79,559 79,277 76,258 14,807 65,957 57,064 54,539                       
  collaboration and license agreements                                                             1,855,500 2,441,000 2,840,000 2,141,000   2,200,000 2,606,000 1,696,000 1,491,000 1,542,000 1,972,000 1,317,597 1,503,592 1,488,918 678,893 597,741 392,728 332,357 219,819   
  revenue under collaboration and license agreements                                                                 1,859,500 2,632,000                 
  operating expenses:                                                                                   
  non-cash accretion of preferred stock deemed dividend                                                                      -7,229,000 -27,085,000 -2,244,000 -186,297 -14,703         
  net income attributable to common stockholders                                                                 -7,349,000 -6,171,000 -8,360,000 -7,553,000 -10,570,000 -16,597,000 -35,921,000 -8,909,000 -5,622,465 -5,198,102   -5,814,381 -5,088,136 -6,266,085 -5,991,936 -6,235,703 -5,110,343 
  weighted-average shares – basic and diluted                                                                  42,317 42,187   41,221             
  weighted-average shares - basic and diluted                                                                    42,067   40,192 36,548 30,722          
  government grants                                                                         11,990 21,785 15,675 31,550 36,544 11,978 43,048 49,453 11,024  
  non-cash stock-based compensation expense                                                                     80,000 103,000 533,000 153,000 341,163 338,653 490,793  524,788 588,806 827,769 879,527 1,225,670 1,679,711 
  basic and diluted net income per share attributable to common stockholders                                                                         -0.135 -0.17         
  basic and diluted net income per share                                                                           -0.18 -0.2 -0.19 -0.17 -0.21 -0.2 -0.22 -0.18 
  non-cash stock-based compensation                                                                            344,391       
  accretion on mandatorily redeemable preferred stock                                                                                   
  license agreements                                                                                 59,307 34,584 
  expenses                                                                                   
  deemed dividend upon issuance of series b mandatorily redeemable preferred stock                                                                                   
  the accompanying notes are an integral part of these financial statements                                                                                   

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