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Unit: USD	2025-09-30	2025-06-30	2025-03-31	2024-12-31	2024-09-30	2024-06-30	2024-03-31	2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2017-06-30	2017-03-31	2016-12-31	2016-09-30	2016-06-30	2016-03-31	2015-12-31	2015-09-30	2015-06-30	2015-03-31	2014-12-31	2014-09-30	2014-06-30	2014-03-31	2013-06-30	2013-03-31	2012-12-31	2012-09-30	2012-06-30	2012-03-31	2011-12-31	2011-09-30	2011-06-30	2011-03-31	2010-12-31	2010-09-30	2010-06-30	2010-03-31	2009-12-31	2009-09-30	2009-06-30	2009-03-31	2008-12-31	2008-09-30	2008-06-30	2008-03-31	2007-12-31	2007-09-30	2007-06-30	2007-03-31	2006-12-31	2006-09-30	2006-06-30	2006-03-31	2005-12-31	2005-09-30	2005-06-30	2005-03-31	2004-12-31	2004-09-30	2004-06-30	2004-03-31	2003-12-31	2003-09-30	2003-06-30	2003-05-04

cash flows from operating activities:
net income	-10,807,000	-44,224,000	-23,403,000	-27,597,000	-27,943,000	6,155,000	25,043,000	-20,919,000	-25,651,000	-26,376,000	-24,271,000	-19,134,000	-20,257,000	-19,328,000	-17,527,000	-14,172,000	-9,562,000	-5,125,000	-3,526,000	-2,618,000	-1,430,000	-1,136,000	-1,150,000	-1,516,000	-697,000	-1,059,000	-1,359,000	-677,000	-1,267,000	-2,453,000	-2,160,000	-2,418,000	-2,590,000	-4,160,000	-2,743,000	-2,522,000	-3,518,000	-3,015,000	-5,795,000	-4,517,000	-3,671,000	-3,374,000	-2,583,000	-2,156,000	-3,535,000	-3,245,000	-3,450,000	-301,000	-408,000	-1,794,000	-1,551,000	-131,000	30,000	-391,000	-815,000	-1,200,000	-207,000	-9,171,000	-1,028,000	-804,000	-1,020,000	-297,000	-1,312,000	-34,000	-1,824,000	-1,389,000	15,191,000	-1,025,000	2,570,000	1,131,000	3,173,000	3,365,000	12,636,000	-5,711,000	9,655,000	1,367,000	877,000	-3,133,000	-8,766,000	-10,182,000	-8,589,000	-9,316,000	-9,230,000	-9,067,000	-10,163,000	-6,685,000	-5,970,000	-4,345,000	-4,617,000
adjustments to reconcile net income to net cash from operating activities:
stock-based compensation	4,402,000	4,581,000	5,225,000	5,744,000	5,608,000	2,604,000	2,335,000	2,129,000	949,000	835,000	673,000	616,000	470,000	485,000	495,000	522,000	572,000	415,000	250,000
gain from change in fair value of warrant liabilities				0	0	-65,142,000	-43,041,000
depreciation and amortization	131,000	218,000	220,000															8,000	1,000	1,000	1,000	6,000	14,000	14,000	14,000	13,000	17,000	17,000	18,000	17,000	17,000	17,000	17,000	16,000	18,000	17,000	13,000	14,000	14,000	13,000	14,000	14,000	4,000	5,000	3,000	4,000	3,000			0	52,000	35,000	35,000	35,000	35,000	40,000	53,000	55,000	58,000	59,000	60,000	61,000	63,000	67,000	66,000	101,000	117,000	117,000	117,000	99,000	83,000	82,000	92,000	85,000	85,000	81,000	94,000	95,000	90,000	91,000	92,000	101,000	100,000	96,000	86,000	85,000	84,000
changes in operating assets and liabilities:
prepaid and other current assets	-390,000	383,000	5,135,000		1,260,000	-5,001,000	-1,333,000		-1,739,000	1,437,000	2,679,000
accounts payable and accrued expenses	2,959,000	34,630,000	538,000		-308,000	42,949,000	-970,000		-846,000	2,096,000	4,565,000
accrued development expense	-2,422,000	-289,000	1,637,000	-103,000	947,000	-201,000	-1,240,000	-4,307,000	300,000	1,768,000	2,996,000	-1,816,000	778,000	393,000	122,000	-448,000	789,000	909,000	834,000	161,000	-197,000	368,000	-390,000	362,000	236,000	-64,000	87,000	156,000	0	-18,000	-381,000	399,000	-32,000	24,000	-19,000	-717,000	103,000	-177,000	-76,000	252,000	194,000	241,000	182,000	-312,000	5,000	31,000	-340,000	190,000	-547,000	136,000	188,000	186,000	-495,000	160,000	178,000	141,000	177,000	-388,000	-462,000	340,000	-453,000	107,000	623,000	-411,000	-127,000	167,000	40,000	-151,000	156,000	-3,099,000	-98,000	-48,000	-1,715,000	3,000	133,000	-677,000	1,857,000	-2,078,000	-380,000	398,000	163,000	578,000	2,214,000
accrued compensation and benefits	-201,000	-292,000	-502,000	-593,000	1,732,000	-10,000	28,000	13,000	-33,000	8,000	42,000	10,000	-16,000	4,000	-1,705,000	1,751,000	6,000	21,000	16,000	3,000	-4,000	12,000	14,000				1,000					11,000	-11,000	7,000	-33,000	-5,000	-594,000	-549,000	860,000	-423,000	146,000	162,000	86,000	-572,000	177,000	168,000	167,000	-735,000	261,000	-224,000	700,000	-709,000	171,000	130,000	153,000	-868,000	-212,000	-617,000	1,325,000	-39,000	-95,000	52,000	-522,000	-572,000	490,000										84,000	-450,000	274,000	85,000	228,000	-451,000	224,000	40,000	-268,000	63,000	211,000	10,000	-182,000
other liabilities	107,000	46,000	-186,000	1,000	149,000	103,000	-260,000	-6,000	98,000	-83,000	-313,000	76,000	42,000	116,000	-370,000																																																19,000	1,000	-17,000
net cash from operating activities	-6,221,000	-4,947,000	-11,336,000	-61,265,000	-18,296,000	-18,241,000	-19,127,000	-22,316,000	-26,530,000	-19,924,000	-13,255,000	-21,320,000	-21,550,000	-11,114,000	-23,530,000	-7,987,000	-14,764,000	-5,139,000	-2,306,000	-1,175,000	-2,171,000	-842,000	-1,194,000	-589,000	-730,000	-591,000	-604,000	-565,000	-1,436,000	-1,126,000	-1,643,000	-1,437,000	-2,151,000	-3,197,000	-1,452,000	-3,031,000	-2,787,000	-3,274,000	-3,142,000	-3,548,000	-2,410,000	-1,948,000	-1,147,000	-2,563,000	-1,672,000	-2,591,000	-2,723,000	-1,801,000	-1,873,000	-1,854,000	-1,297,000	-1,950,000	-2,070,000	-809,000	-1,173,000	-1,547,000	3,269,000	-3,339,000	3,430,000	560,000	-794,000	-2,040,000	-5,256,000	-3,614,000	-3,781,000	-4,394,000	17,469,000	-3,522,000	1,610,000	-2,732,000	-517,000	-1,307,000	6,787,000	-10,200,000	6,848,000	-4,849,000	-3,626,000	140,514,000	-9,772,000	-9,757,000	-7,753,000				-6,920,000	-6,371,000	-5,892,000
capex	0	0	0	-57,000	-17,000	0	0	-41,000	-22,000	6,000	-357,000	335,000	-1,156,000	-1,466,000	-425,000	-100,000	-22,041,000	0	0	0	0	0	0	0	0	0	-18,000	0	0	0	0	0	0	0	0	1,000	0	0	0	0	0	0	-195,000	-1,000	0	0	-79,000	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-157,000	-426,000	-65,000	-48,000	0	0	0	-94,000	-39,000	-272,000	-117,000	-35,000				-208,000	0	0
free cash flows	-6,221,000	-4,947,000	-11,336,000	-61,322,000	-18,313,000	-18,241,000	-19,127,000	-22,357,000	-26,552,000	-19,918,000	-13,612,000	-20,985,000	-22,706,000	-12,580,000	-23,955,000	-8,087,000	-36,805,000	-5,139,000	-2,306,000	-1,175,000	-2,171,000	-842,000	-1,194,000	-589,000	-730,000	-591,000	-622,000	-565,000	-1,436,000	-1,126,000	-1,643,000	-1,437,000	-2,151,000	-3,197,000	-1,452,000	-3,030,000	-2,787,000	-3,274,000	-3,142,000	-3,548,000	-2,410,000	-1,948,000	-1,342,000	-2,564,000	-1,672,000	-2,591,000	-2,802,000	-1,801,000	-1,873,000	-1,854,000	-1,297,000	-1,950,000	-2,070,000	-809,000	-1,173,000	-1,547,000	3,269,000	-3,339,000	3,430,000	560,000	-794,000	-2,040,000	-5,256,000	-3,614,000	-3,781,000	-4,394,000	17,469,000	-3,522,000	1,610,000	-2,889,000	-943,000	-1,372,000	6,739,000	-10,200,000	6,848,000	-4,849,000	-3,720,000	140,475,000	-10,044,000	-9,874,000	-7,788,000				-7,128,000	-6,371,000	-5,892,000
cash flows from investing activities:
purchases of property and equipment				-57,000	-17,000																			0	0	0	-18,000									1,000				0	0	0	-195,000	-1,000	0	0	-79,000																												0	0	-94,000
net cash from investing activities				-57,000	-17,000			-41,000	-22,000	6,000	-357,000	335,000	-1,156,000	-1,466,000	-425,000	-100,000	-22,041,000							0	0	0	-18,000							0	2,101,000	-1,544,000	-625,000	1,500,000	-1,497,000	900,000	51,000	1,051,000	-2,194,000	1,101,000	-851,000	1,001,000	-79,000	1,501,000	4,103,000	-2,605,000	10,517,000	7,005,000	2,705,000	2,503,000	10,000,000	4,998,000	42,402,000	-13,320,000	35,935,000	15,174,000	14,674,000	8,545,000	-110,939,000	-24,208,000	23,374,000	12,640,000	1,637,000	7,321,000	58,638,000	46,997,000	-8,063,000	-9,190,000	39,347,000	-5,577,000	-26,519,000	-12,152,000	-24,894,000	-46,516,000	8,741,000	12,069,000	6,425,000
cash flows from financing activities:
proceeds from exercise of common stock warrants, net of exercise costs				0	0	101,392,000	22,160,000
proceeds from issuance of common stock upon exercise of stock options	0	0	90,000					1,143,000	464,000	889,000	64,000	9,000	136,000	119,000	211,000	0
net cash from financing activities	0	0	90,000	918,000	0	101,392,000	22,160,000	1,143,000	464,000	889,000	64,000	47,338,000	136,000	119,000	211,000	0	75,000	1,274,000	190,992,000									-72,000	12,272,000	0	1,898,000					-24,000	0	-214,000	-46,000					0	0	313,000	66,000	254,000	6,000	-34,426,000	0			-259,000	52,000	4,485,000	4,425,000	-84,835,000	154,000	382,000	983,000	120,000	164,000	232,000	39,000	962,000	-581,000	-9,181,000	-16,008,000	1,488,000	203,000	-2,128,000	-704,000	605,000	120,000	285,000	694,000	232,000	-60,000	93,000	56,000				47,000	621,000	46,446,000
net increase in cash and cash equivalents	-6,301,000	-4,947,000	-11,246,000			83,122,000	3,033,000					26,353,000	-22,570,000	-12,461,000	-23,744,000	-8,087,000	-36,730,000	-3,938,000	188,686,000									-637,000			255,000				649,000										-2,523,000	-1,277,000	-2,736,000	-46,000	2,236,000	-38,885,000	9,220,000	5,241,000	635,000	1,435,000	8,879,000	7,936,000	50,096,000	-101,494,000	39,519,000	16,116,000	14,863,000	6,625,000	-116,031,000	-27,590,000	19,632,000	9,208,000	18,525,000	-5,382,000	44,240,000	45,753,000	-8,377,000	-12,625,000	45,430,000	-15,172,000	-19,551,000			94,230,000	-1,091,000	2,405,000	-1,272,000	-371,000	-1,422,000	-4,009,000	-4,846,000	-34,873,000	4,354,000
cash and cash equivalents at beginning of period	0	0	128,574,000			0	121,136,000	0	0	0	201,015,000	0	0	0	233,437,000	0	0	0	93,506,000	0	0	0	23,081,000	0	0	0	19,807,000	0	0	0	10,479,000	0	0																																		0	0	86,567,000	0	0	0	16,386,000	0	0	0	95,651,000	0	0	0	1,379,000	0	0	0	12,027,000	0	0	0	50,091,000
cash and cash equivalents at end of period	-6,301,000	-4,947,000	117,328,000			83,122,000	124,169,000	-21,214,000	-26,088,000	-19,029,000	187,467,000	26,353,000	-22,570,000	-12,461,000	209,693,000	-8,087,000	-36,730,000	-3,938,000	282,192,000	69,432,000	-1,180,000	-346,000	25,600,000	5,277,000	-730,000	-591,000	19,125,000	-637,000	10,836,000	-1,126,000	10,734,000	-1,437,000	-2,151,000																																		18,525,000	-5,382,000	130,807,000	45,753,000	-8,377,000	-12,625,000	61,816,000	-15,172,000	-19,551,000	-16,716,000	67,825,000	94,230,000	-1,091,000	2,405,000	107,000	-371,000	-1,422,000	-4,009,000	7,181,000	-34,873,000	4,354,000	-3,118,000	45,664,000
supplemental cash flow information:
non-cash financing activities
issuance of warrants resulting in recognition of warrant liabilities				0	0	0	113,363,000
derecognition of warrant liabilities upon exercise of warrants				0	0	-226,000	-4,954,000
depreciation				228,000	228,000	246,000	250,000	267,000	273,000	272,000	272,000	271,000	181,000	174,000	178,000	179,000
amortization of intangible assets				32,000	31,000	56,000	61,000	89,000	119,000	119,000	119,000	118,000	119,000	125,000	135,000	134,000
prepaid expenses and other current assets
operating lease right-of-use assets and liabilities								0	0	0	-17,000	-3,000	-2,000	-3,000	-1,000	-2,000	-1,000	6,000	25,000
accounts payable and other accrued expenses
proceeds from common stock offering, net of issuance costs
non-cash investing activities
purchases of property and equipment included in accounts payable
net increase in cash, cash equivalents and restricted cash
cash, cash equivalents and restricted cash at beginning of period
cash, cash equivalents and restricted cash at end of period
reconciliation to condensed consolidated balance sheet:
cash and cash equivalents
restricted cash
cash, cash equivalents and restricted cash
prepaid and other assets												-1,601,000	-1,641,000	5,494,000	-1,063,000	-854,000	-7,866,000
purchase of property and equipment								-41,000	-22,000	6,000	-357,000	335,000	-1,156,000	-1,466,000	-425,000	-100,000	-22,041,000																																																					-157,000	-426,000	-65,000	-48,000					-39,000	-272,000	-117,000	-35,000	191,000	-62,000	-77,000	-208,000
proceeds from issuance of common stock upon exercise of 2018 warrants
net decrease in cash and cash equivalents									-26,088,000	-19,029,000	-13,548,000																					-1,437,000	-2,151,000			-4,599,000	-3,412,000	-1,988,000	-4,685,000	-2,694,000	-2,359,000	-897,000	-3,341,000																																		-27,826,000
gain on sale of property and equipment																				0	0	-246,000	-100,000
accounts payable												143,000	-1,224,000	1,426,000	-3,794,000	4,781,000	433,000	1,048,000	-47,000	446,000	49,000	-192,000	155,000	113,000	-254,000	99,000	201,000	-255,000	-413,000			-288,000	54,000	93,000	270,000	-760,000	705,000	-665,000	9,000	116,000	433,000	210,000	82,000	-649,000	462,000	-68,000	-17,000	69,000	5,000	-146,000	6,000	-1,000	38,000	-92,000	-48,000	168,000	-671,000	392,000	90,000	140,000	-832,000	312,000	30,000	-710,000	-531,000	-1,269,000	279,000	244,000	-662,000	616,000	788,000	1,380,000	-145,000	547,000	-158,000	-224,000	-178,000	434,000	-442,000	102,000	27,000	46,000	14,000	-3,078,000	1,664,000	-96,000	1,806,000
proceeds from sale of property and equipment																				0	0	260,000	100,000
proceeds from issuance of common stock upon exercise of common stock warrants																0
other current liabilities																	653,000	0	-44,000			3,000	2,000	2,000	-7,000	2,000	12,000		-4,000	2,000	10,000
proceeds from registered direct offering, net of issuance costs																	0	0	189,825,000
proceeds from exercise of stock options																		1,274,000	475,000	0
proceeds from exercise of common stock warrants																		0	692,000	356,000	735,000	236,000	3,613,000
other current assets																			185,000	509,000	-811,000			129,000	-336,000	91,000	93,000	43,000	-246,000	82,000	72,000	104,000	-276,000	114,000	230,000	104,000	-341,000	184,000	139,000	194,000	-320,000	-81,000	120,000	119,000	124,000	-341,000	124,000	124,000	126,000	125,000	-283,000	380,000	-117,000	-274,000	0	0	60,000	-2,160,000	-268,000	2,163,000	531,000				171,000	-133,000	-376,000	279,000	-8,000	2,559,000			38,000
receivable from exercise of stock options																			1,271,000
non-cash stock-based compensation																				238,000	228,000	252,000	270,000	304,000	319,000	329,000	344,000	403,000	484,000	699,000	802,000	750,000	687,000	709,000	827,000	845,000	845,000	934,000	1,710,000	818,000	795,000	882,000	962,000	1,004,000	1,090,000	884,000	783,000																																						52,000
issuance costs from 2018 sale of common stock and warrants																								0	0	0	-60,000
proceeds from follow-on public offering, net of issuance costs
net cash from / (used in) investing activities																					0	260,000	100,000
net cash from / (used in) financing activities																					991,000	236,000	3,613,000
net increase / (decrease) in cash and cash equivalents																					-1,180,000	-346,000	2,519,000
proceeds from sale of common stock and warrants
proceeds from issuance of common stock and warrants, net of issuance costs
net cash (used in) / provided by financing activities																									0	0	-60,000
net (decrease) / increase in cash and cash equivalents																											-682,000
non-cash net interest income																																																-1,000	-7,000	-3,000	75,000	137,000	133,000	168,000	287,000	300,000	386,000	174,000	304,000	43,000	731,000	172,000	-678,000	-121,000	649,000	172,000	123,000	-164,000	942,000	-316,000	192,000	-147,000	950,000							62,000	245,000
other non-current assets
purchases of marketable securities																																0	0	0	-399,000	-2,095,000	-549,000	0	-1,497,000	0	-899,000	-949,000	-1,999,000	2,000	-1,101,000	-249,000	-1,250,000	-1,299,000	-2,797,000		-4,286,000	-4,795,000	-4,795,000						-18,912,000	-13,177,000	-18,677,000														-35,351,000	-30,267,000	-46,284,000
sales of marketable securities																																0	0	0	400,000																														2,024,000	4,040,000	3,759,000	7,322,000	37,766,000	65,992,000	2,478,000	51,586,000	79,625,000	6,265,000	2,132,000	3,660,000	15,204,000						32,639,000
maturities of marketable securities																																0	0	0	2,100,000	550,000	0			900,000	950,000			1,100,000	250,000	1,250,000	1,250,000	2,800,000	6,900,000	4,287,000	14,803,000	11,800,000	7,500,000	5,000,000	10,000,000	4,998,000	42,402,000	1,667,000	47,440,000	28,351,000	33,351,000	19,000,000	8,000,000	0	21,350,000	8,600,000	0	-1,000	20,872,000	0	2,000,000	4,000,000	2,500,000	12,375,000	6,700,000	14,455,000	6,280,000						0
proceeds from issuance of common stock, net of issuance costs																													12,272,000	0	1,898,000
net cash provided (used in) investing activities																																0
cash from statutory taxes for net exercise of performance awards																																					0
deferred financing costs																																				-24,000	0	0	-46,000
cash flows used in operating activities:
cash and cash equivalents at beginning of the period																																			16,615,000	0	0	0	31,299,000	0	0	0	40,590,000	0	0	0	48,588,000	0	49,355,000		0	0	73,144,000		0	0	4,798,000		0	0	35,794,000		0	0	153,158,000
cash and cash equivalents at end of the period																																			17,264,000	-4,599,000	-3,412,000	-1,988,000	26,614,000	-2,694,000	-2,359,000	-897,000	37,249,000	-1,462,000	-2,523,000	-1,277,000	45,852,000	-46,000	51,591,000		9,220,000	5,241,000	73,779,000		8,879,000	7,936,000	54,894,000		39,519,000	16,116,000	50,657,000		-116,031,000	-27,590,000	172,790,000
proceeds from issuance of common stock																																												0	0	313,000	66,000	254,000	6,000		0							566,000	154,000	382,000	983,000	129,000	164,000	232,000	39,000	664,000	-580,000	252,000	765,000	1,489,000	203,000	817,000	143,000	543,000	120,000	285,000	694,000	232,000	-60,000	93,000	56,000	54,390,000	-2,000	368,000	47,000
statutory taxes for net exercise of performance awards
cash flows used in financing activities:
cash flows used in investing activities:
deferred program fee revenue																																																-1,959,000	-1,958,000	-2,468,000	-2,725,000	-2,724,000	-2,724,000					-15,496,000	10,047,000	-2,523,000	-2,524,000	-3,587,000	-3,587,000	-3,587,000	-3,587,000	-3,587,000	-3,588,000	-3,587,000	-3,586,000						-6,550,000	-6,550,000	-6,550,000
deferred tax liabilities
other assets																																													0										86,000	0	-11,000		1,000	5,000	1,578,000					-1,061,000				0
adjustments to reconcile net income to net cash used
in operating activities:
excess tax benefits from equity-based compensation plans
nondividend distribution
other accrued liabilities																																															7,000	0	-24,000	0	-17,000	7,000	-48,000	-14,000	-14,000	16,000	-3,000	-5,000	-24,000	-173,000	-188,000	-52,000	-108,000	185,000	-369,000	533,000	517,000	-945,000	555,000	297,000	500,000	-780,000	593,000	300,000	28,000	-1,763,000	1,660,000	71,000	-24,000	-17,000	11,000			0	-6,000	-69,000	-1,000
adjustments to reconcile net income to net cash
used in operating activities:
non-cash stock based compensation																																																812,000	679,000	2,577,000	2,257,000	869,000	907,000	1,211,000	1,491,000	1,423,000	1,303,000	16,206,000	1,159,000	1,349,000	1,418,000	1,793,000	1,672,000	1,575,000	1,619,000	1,804,000	5,165,000	1,710,000	1,526,000	2,017,000	1,630,000	1,429,000	1,218,000			1,435,000	1,685,000	89,000	69,000	123,000	-33,000	69,000	20,000
receivables																																																						640,000	199,000	1,157,000	5,118,000
other non-current liabilities
purchase of marketable securities																																																														-10,435,000	-118,917,000			0				-18,838,000	-12,115,000	-64,711,000	-42,730,000					-61,129,000	-8,911,000	-16,994,000	-6,557,000	-57,367,000	-26,124,000	-8,109,000	-22,467,000
proceeds from (cash used in) issuance of common stock
cash and cash equivalents at beginning of the year
cash and cash equivalents at end of the year
cash received for income taxes
tax benefits from equity-based compensation plans
cash paid (received) for income taxes
program fee revenue																																																							-2,725,000	-2,724,000	-2,724,000
proceeds from sales of marketable securities
proceeds from exercise of common stock options																																																							52,000	4,485,000	4,425,000
loss on disposal of property and equipment																																																																										0
purchase of stock pursuant to the stock repurchase plan																																																																		0	-1,000	-9,433,000	-16,773,000
non-cash tax benefit from carry-back																																																															-363,000	-1,000	-321,000
cash paid for income taxes																																																														-4,000	847,000	0	334,000					0	0	0	2,800,000
income taxes payable																																																																						-67,000	0	0	-2,712,000	-800,000
other current assets and other assets																																																															-1,093,000
proceeds from the sales of marketable securities																																																															-22,000
collaboration revenue receivable																																																																							0	0	2,382,000		3,709,000	-2,071,000	-3,345,000
recognition of program fees
purchase of treasury stock																																																																							0	-2,945,000	-847,000
amortization of program fees																																																																								-6,550,000	-6,550,000
non-cash change in interest income																																																																											-770,000	-432,000	-498,000
prepaid expenses																																																																											-298,000	78,000	498,000	-83,000	-505,000	117,000	107,000	156,000	-369,000	309,000	966,000
accrued income tax
stock subscription note payments received																																																																																						98,000	0
non-cash interest income																																																																																			-360,000	30,000	270,000
sales and maturities of marketable securities																																																																															17,924,000	29,180,000	13,017,000				24,702,000	2,258,000
proceeds from issuance of preferred stock
non-cash expense for warrants issued
cash flows from (used in) investing activities:
net cash from investment activities																																																																																					2,027,000
non-cash stock based compensation expense and other																																																																																							-27,000
prepaid and other incomes
proceeds from issuance of various preferred stock
proceeds from public offerings
proceeds from issuance of common stock pursuant to employee stock plans and warrants
interest receivable
proceeds from initial public offering
proceeds from issuance of series b redeemable convertible preferred stock
proceeds from issuance of series c redeemable convertible preferred stock
repayment (funding) of notes receivable by stockholders
proceeds from issuance of series a convertible preferred stock

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