7Baggers

Pulse Biosciences, Inc
(NASDAQ:PLSE) 

PLSE stock logo

Pulse Biosciences, Inc. operates as a novel bioelectric medicine company. It offers CellFX System, a tunable, software-enabled, and console-based platform that delivers nano second duration pulses of electrical energy to non-thermally clear targeted cells while sparing adjacent non-cellular tissue p...

Founded: 2014
Full Time Employees: 82
Sector: Healthcare
Industry: Medical Instruments & Supplies
Healthcare
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• Market Cap:
• Exchange:
• Shs Outstanding:
• Employees:
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• Return on Equity (ROE) ttm:
• Return on Assets (ROA) ttm:
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At a glance:
Bull Thesis:
Bear Thesis:
Main Competitors:
Moat:
Income Statements:
Quarterly
Annual
    Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 
                                             
      revenue:
    		                                         
      product revenue
    		401,000 264,000 86,000                                       
      cost and expenses:
    		                                         
      cost of product revenue
    		370,000 260,000 279,000                                       
      research and development
    		12,590,000 10,927,000 11,393,000 12,088,000 10,313,000 10,662,000 7,703,000 7,230,000 6,741,000 7,799,000 7,472,000 6,697,000 5,829,000  4,517,000 5,458,000 6,769,000  6,460,000 7,459,000 9,063,000  6,968,000 5,870,000 6,181,000  6,192 6,337 5,842,000  5,038 3,960 3,175,000  3,200 2,282 1,851,000  1,739 1,453 990,000 
      selling, general and administrative
    		6,591,000 7,330,000 8,781,000                                       
      total cost and expenses
    		19,551,000 18,517,000 20,453,000 20,275,000 18,044,000 20,261,000 13,655,000 11,726,000 10,615,000 12,533,000 11,252,000 10,227,000 9,562,000  18,025,000 14,279,000 17,717,000  14,847,000                       
      income from operations
    		-19,150,000 -18,253,000 -20,367,000 -20,275,000 -18,044,000 -20,261,000 -13,655,000 -11,726,000 -10,615,000 -12,533,000 -11,252,000 -10,227,000 -9,562,000  -18,025,000 -14,014,000 -17,273,000  -14,273,000                       
      yoy
    		6.13% -9.91% 49.15% 72.91% 69.99% 61.66% 21.36% 14.66% 11.01%  -37.58% -27.02% -44.64%  26.29%                           
      qoq
    		4.91% -10.38% 0.45% 12.36% -10.94% 48.38% 16.45% 10.47% -15.30% 11.38% 10.02% 6.95%   28.62% -18.87%                          
      operating margin %
    		-Infinity% -Infinity% -Infinity% NaN% NaN% -Infinity% NaN% NaN% NaN% -Infinity% NaN% NaN% NaN% NaN% NaN% -5288.30% -3890.32% NaN% -2486.59% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% NaN% 
      other income:
    		                                         
      interest income
    		593,000 825,000 1,001,000 1,107,000 1,249,000 876,000 975,000 343,000 478,000 600,000 686,000 317,000 -239,000  -14,000 18,000   -9,000 -517,000 -114,000  9,000 21,000 78,000  218 290 332,000  118 137 56,000  39 41 39,000  31 3  
      other expense
    		-24,000 -5,000 -19,000                                       
      total other income
    		569,000 820,000 982,000 1,107,000 1,249,000 876,000 975,000 343,000 478,000 600,000 686,000 317,000 -239,000  -14,000 18,000   -9,000 -517,000 -114,000  9,000 21,000 78,000  218 290 332,000  118 137 56,000  39 41 39,000  31 3  
      net income
    		-18,581,000 -17,433,000 -19,385,000 -19,168,000 -16,795,000 -19,385,000 -12,680,000 -11,383,000 -10,137,000 -11,933,000 -10,566,000 -9,910,000 -9,801,000  -18,039,000 -13,996,000 -17,273,000  -14,282,000 -15,323,000 -18,639,000  -12,896,000 -11,333,000 -11,872,000  -11,746 -11,359 -10,078,000  -10,761 -9,163 -8,668,000  -7,486 -6,180 -3,198,000  -2,767 -2,258 -1,684,000 
      yoy
    		10.63% -10.07% 52.88% 68.39% 65.68% 62.45% 20.01% 14.86% 3.43%  -41.43% -29.19% -43.26%  26.31% -8.66% -7.33%  10.75% 35.21% 57.00%  109690.57% 99671.11% 17.80%  9.15% 23.97% 16.27%  43.75% 48.27% 171.04%  170.55% 173.69% 89.90%     
      qoq
    		6.59% -10.07% 1.13% 14.13% -13.36% 52.88% 11.39% 12.29% -15.05% 12.94% 6.62% 1.11%   28.89% -18.97%   -6.79% -17.79%   13.79% -4.54%   3.41% -99.89%   17.44% -99.89%   21.13% -99.81%   22.54% -99.87%  
      net income margin %
    		-Infinity% -Infinity% -Infinity% NaN% NaN% -Infinity% NaN% NaN% NaN% -Infinity% NaN% NaN% NaN% NaN% NaN% -5281.51% -3890.32% NaN% -2488.15% -Infinity% -Infinity% NaN% -Infinity% -Infinity% -Infinity% NaN% -Infinity% -Infinity% -Infinity% NaN% -Infinity% -Infinity% -Infinity% NaN% -Infinity% -Infinity% -Infinity% NaN% -Infinity% -Infinity% -Infinity% 
      comprehensive loss
    		-18,581,000 -17,433,000 -19,385,000 -19,168,000 -16,795,000 -19,385,000 -12,680,000 -11,383,000 -10,137,000 -11,933,000 -10,566,000 -9,910,000 -9,801,000  -18,039,000 -13,996,000 -17,273,000  -14,282,000 -15,323,000 -18,638,000  -12,895,000 -11,350,000 -11,859,000  -11,760 -11,339 -10,075,000  -10,764 -9,160 -8,620,000  -7,482 -6,177 -3,200,000     
      net income per share
    		-0.27 -0.26 -0.29                                       
      weighted-average common shares outstanding, basic and diluted
    		67,994,566 67,395,339 67,385                                       
      revenues:
    		                                         
      product revenues
    		               265,000 444,000  574,000                       
      total revenues
    		               265,000 444,000  574,000                       
      yoy
    		   NaN% NaN%  NaN% NaN% NaN%  NaN% NaN% NaN%  NaN%                           
      qoq
    		   NaN%   NaN% NaN%   NaN% NaN%   NaN% -40.32%                          
      general and administrative
    		   8,187,000 7,731,000 9,599,000 5,952,000 4,496,000 3,874,000 4,734,000 3,780,000 3,530,000 3,733,000  3,088,000 3,787,000 4,498,000  4,256,000 4,200,000 5,316,000  5,771,000 5,317,000 5,603,000  5,606 5,146 4,401,000  5,675 5,173 5,383,000  4,159 3,772 1,220,000  893 642 528,000 
      loss from operations, before income taxes
    		   -19,168,000 -16,795,000 -19,385,000 -12,680,000 -11,383,000 -10,137,000 -11,933,000 -10,566,000 -9,910,000 -9,801,000                        -3,198,000  -2,767 -2,258 -1,684,000 
      income tax benefit
    		                                         
      basic and diluted net loss per share
    		   -0.28 -0.25 -0.32 -0.21 -0.2 -0.18 -0.22 -0.19 -0.22 -0.26  -0.49 -0.44 -0.58  -0.48 -0.58 -0.71  -0.51 -0.53 -0.57  -0.57 -0.55 -0.49  -0.64 -0.54 -0.51  -0.52 -0.43 -0.23     
      weighted-average shares used for eps calculation
    		   67,276 67,126 58,398 61,066 57,180 55,172 48,038 54,923 44,512 37,390 33,935 37,158 31,492 29,745 27,964 29,612 26,477 26,072 23,248 25,223 21,528 20,838 20,746 20,774 20,728 20,679 17,078 16,927 16,881 16,842 14,754 14,381 14,233 13,803 11,009    
      cost of revenues
    		              8,400,000 1,344,000 909,000  727,000                       
      sales and marketing
    		              2,020,000 3,690,000 5,541,000  3,404,000 3,147,000 4,146,000                     
      other comprehensive gain:
    		                                         
      unrealized gain on available-for-sale securities
    		                    1,000  1,000 -17,000 13,000   20 3,000   3          
      revenue
    		                                         
      operating expenses:
    		                                         
      total operating expenses
    		                   14,806,000 18,525,000  12,905,000 11,354,000 11,950,000  11,964 11,649 10,410,000  10,879 9,300 8,724,000  7,525 6,221 3,237,000  2,798 2,261 1,684,000 
      other comprehensive loss:
    		                                         
      amortization of intangible assets
    		                      166,000 167,000 166,000  166 166 167,000  166 167 166,000  166 167 166,000  166 166 166,000 
      unrealized gains on available-for-sale securities
    		                          -14               
      unrealized gain on available-for-sale securities, net of tax
    		                                48,000  4 3      
      income tax
    		                                         
      unrealized loss on available-for-sale securities, net of tax
    		                                         
      net loss per common share – basic and diluted
    		                                      -0.21 -0.23 -220 
      weighted-average number of common shares outstanding – basic and diluted
    		                                      13,315 9,791 7,565,000 
      income taxes
    		                                         
    Balance Sheets:
    Quarterly
    Annual
      Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 
                                               
        assets
      		                                         
        current assets:
      		                                         
        cash and cash equivalents
      		68,319,000 80,735,000 95,214,000 106,349,000 119,279,000 118,038,000 79,033,000 26,196,000 34,885,000 44,365,000 50,386,000 58,747,000 54,098,000 61,139,000 69,162,000 14,798,000 12,676,000 28,614,000 41,991,000 47,426,000 59,883,000 12,463,000 7,070,000 37,765,000 7,864,000 6,899,000 9,570,000 10,780,000 8,536,000 51,103,000 6,331,000 6,794,000 10,667,000 3,386,000 32,423,000 1,990,000 2,751,000 2,089,000 4,628,000 20,214,000  
        accounts receivable
      		157,000 274,000 15,000            5,000 8,000 21,000 61,000 72,000                       
        inventory
      		206,000 136,000 57,000 51,000 30,000          750,000 7,871,000 7,487,000 5,824,000 4,281,000 2,691,000 1,135,000                     
        prepaid expenses and other current assets
      		2,448,000 2,276,000 1,871,000 1,760,000 1,600,000 1,411,000 1,381,000 1,043,000 964,000 963,000 1,237,000 1,211,000 849,000 1,008,000 1,244,000 1,062,000 1,979,000 2,131,000 2,866,000 3,267,000 958,000 1,864,000 748,000 907,000 545,000 1,005,000 1,437,000 1,908,000 550,000 779,000 1,095,000 1,161,000 368,000 412,000 512,000 717,000 253,000 268,000 294,000 337,000 47,000 
        total current assets
      		71,130,000 83,421,000 97,157,000 108,160,000 120,909,000 119,449,000 80,414,000 27,239,000 35,849,000 45,328,000 51,623,000 59,958,000 54,947,000 62,147,000 71,161,000 23,739,000 22,163,000 36,630,000 49,210,000 61,755,000 61,976,000 22,339,000 30,334,000 38,672,000 16,431,000 26,403,000 35,935,000 44,550,000 53,351,000 60,362,000 22,116,000 28,660,000 33,743,000 38,481,000 42,553,000 16,116,000 19,113,000 16,663,000 19,007,000 21,046,000 2,645,000 
        property and equipment
      		1,016,000 1,051,000 1,055,000 1,109,000 1,062,000 1,160,000 1,221,000 1,313,000 1,400,000 1,528,000 1,648,000 1,755,000 1,865,000 1,961,000 2,286,000 2,386,000 2,554,000 2,462,000 2,446,000 2,460,000 2,430,000 2,478,000 2,562,000 2,591,000 2,633,000 2,566,000 2,428,000 1,985,000 2,056,000 2,173,000 2,339,000 2,432,000 2,451,000 2,570,000 2,635,000 2,730,000      
        intangible assets
      		408,000 575,000 741,000 907,000 1,054,000 1,220,000 1,386,000 1,553,000 1,719,000 1,886,000 2,052,000 2,218,000 2,384,000 2,551,000 2,717,000 2,883,000 3,050,000 3,216,000 3,382,000 3,549,000 3,715,000 3,882,000 4,048,000 4,214,000 4,381,000 4,547,000 4,713,000 4,880,000 5,046,000 5,213,000 5,379,000 5,545,000 5,712,000 5,878,000        
        goodwill
      		2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 2,791,000 
        right-of-use assets
      		5,702,000 6,010,000 6,316,000 6,607,000 6,889,000 7,163,000 6,588,000 6,818,000 7,040,000 7,256,000 7,466,000 7,670,000 7,869,000 8,062,000 8,250,000 8,433,000 8,611,000 8,785,000 8,954,000 9,119,000 9,280,000 9,438,000 9,595,000 9,749,000 5,043,000 5,114,000 1,190,000 1,182,000              
        other assets
      		575,000 691,000 705,000 677,000 678,000 677,000 646,000 714,000 365,000 365,000 365,000 365,000 365,000 365,000 365,000 365,000 365,000 365,000 365,000 365,000 365,000 365,000 365,000 365,000 562,000 494,000 1,645,000               
        total assets
      		81,622,000 94,539,000 108,765,000 120,251,000 133,383,000 132,460,000 93,046,000 40,428,000 49,164,000 59,154,000 65,945,000 74,757,000 70,221,000 77,877,000 87,570,000 40,597,000 39,534,000 54,249,000 67,148,000 80,039,000 80,557,000 41,293,000 49,695,000 58,382,000 31,841,000 41,915,000 48,702,000 57,033,000 63,452,000 70,640,000 32,726,000 39,529,000 44,798,000 49,821,000 54,124,000 27,948,000 28,574,000 26,314,000 28,830,000 31,057,000 12,824,000 
        liabilities and stockholders’ equity
      		                                         
        current liabilities:
      		                                         
        accounts payable
      		2,761,000 2,777,000 2,978,000 2,742,000 2,370,000 1,673,000 1,727,000 1,637,000 1,712,000 1,836,000 1,412,000 1,794,000 2,160,000 1,573,000 2,022,000 1,948,000 3,486,000 2,904,000 2,706,000 2,823,000 2,164,000 1,717,000 1,432,000 1,489,000 1,214,000 1,963,000 1,816,000 1,577,000 1,200,000 1,272,000 1,281,000 1,502,000 944,000 782,000 914,000 851,000 782,000 265,000 446,000 333,000 296,000 
        accrued liabilities
      		5,408,000 3,576,000                                        
        lease liability, current
      		1,627,000 1,570,000 1,519,000 1,459,000 1,406,000 1,355,000 1,193,000 1,146,000 1,101,000 1,058,000 1,016,000 975,000 935,000 896,000 858,000 827,000 799,000 774,000 749,000 719,000 629,000 542,000 457,000 278,000 98,000  177,000 168,000 396,000             
        total current liabilities
      		9,796,000 7,923,000 9,700,000 8,978,000 7,760,000 10,055,000 6,741,000 5,962,000 5,081,000 6,708,000 5,432,000 5,613,000 6,991,000 5,981,000 6,998,000 7,564,000 8,905,000 8,519,000 9,519,000 9,844,000 8,528,000 7,585,000 6,000,000 4,890,000 3,383,000 4,459,000 4,047,000 3,448,000 3,115,000 3,108,000 3,348,000 3,072,000 2,191,000 2,213,000 2,474,000 1,972,000 1,242,000 1,016,000 967,000 590,000 650,000 
        lease liability, less current portion
      		5,528,000 5,960,000 6,371,000 6,786,000 7,171,000 7,543,000 7,174,000 7,497,000 7,796,000 8,086,000 8,368,000 8,644,000 8,898,000 9,144,000    10,040,000    10,814,000  11,164,000                  
        total liabilities
      		15,324,000 13,883,000 16,071,000 15,764,000 14,931,000 17,598,000 13,915,000 13,459,000 12,877,000 14,794,000 13,800,000 14,257,000 80,889,000 80,125,000 81,381,000 17,182,000 18,738,000 18,559,000 19,761,000 20,289,000 60,160,000 18,399,000 16,991,000 16,054,000 10,073,000 11,178,000 7,721,000 7,172,000 4,338,000 4,306,000 4,652,000 4,482,000 3,703,000 3,826,000 4,189,000 3,788,000      
        stockholders’ equity:
      		                                         
        preferred stock, 0.001 par value...
      		                                         
        common stock, 0.001 par value...
      		68,000 68,000 68,000 67,000 67,000 66,000 62,000 55,000 55,000 55,000 55,000 55,000 37,000 37,000    29,000    25,000    21,000    21,000    17,000    13,000    
        additional paid-in capital
      		548,092,000 543,869,000 538,474,000 530,883,000 525,680,000 505,296,000 450,184,000 385,349,000 383,284,000 381,220,000 377,072,000 374,861,000 293,801,000 292,420,000 291,660,000 290,847,000 274,240,000 271,861,000 268,142,000 266,223,000 211,550,000 195,410,000 191,468,000 188,197,000 156,291,000 153,401,000 149,853,000 146,973,000 144,887,000 142,032,000 94,825,000 91,034,000 87,922,000 84,202,000 79,391,000 46,135,000 43,131,000 37,898,000 37,655,000 37,484,000 16,938,000 
        accumulated deficit
      		-481,862,000 -463,281,000 -445,848,000 -426,463,000 -407,295,000 -390,500,000 -371,115,000 -358,435,000 -347,052,000 -336,915,000 -324,982,000 -314,416,000 -304,506,000 -294,705,000 -285,508,000 -267,469,000 -253,473,000 -236,200,000 -220,784,000 -206,502,000 -191,179,000 -172,540,000 -158,790,000 -145,894,000 -134,561,000 -122,689,000 -108,901,000 -97,155,000 -85,796,000 -75,718,000 -66,765,000 -56,004,000 -46,841,000 -38,173,000 -29,470,000 -21,984,000 -15,804,000 -12,606,000 -9,797,000 -7,030,000 -4,772,000 
        total stockholders’ equity
      		66,298,000 80,656,000 92,694,000 104,487,000 118,452,000 114,862,000 79,131,000 26,969,000 36,287,000 44,360,000 52,145,000 60,500,000   6,189,000 23,415,000 20,796,000 35,690,000 47,387,000 59,750,000 20,397,000 22,894,000 32,704,000 42,328,000 21,768,000 30,737,000 40,981,000 49,861,000 59,114,000 66,334,000 28,074,000 35,047,000 41,095,000 45,995,000 49,935,000 24,160,000 27,332,000 25,298,000 27,863,000 30,467,000 12,174,000 
        total liabilities and stockholders’ equity
      		81,622,000 94,539,000 108,765,000 120,251,000 133,383,000 132,460,000 93,046,000 40,428,000 49,164,000 59,154,000 65,945,000 74,757,000 70,221,000 77,877,000 87,570,000 40,597,000 39,534,000 54,249,000 67,148,000 80,039,000 80,557,000 41,293,000 49,695,000 58,382,000 31,841,000 41,915,000 48,702,000 57,033,000 63,452,000 70,640,000 32,726,000 39,529,000 44,798,000 49,821,000 54,124,000 27,948,000 28,574,000 26,314,000 28,830,000 31,057,000 12,824,000 
        accrued expenses
      		  5,203,000 4,777,000 3,984,000 7,027,000 3,821,000 3,179,000 2,268,000 3,814,000 3,004,000 2,844,000 3,091,000 2,595,000 3,982,000 4,757,000 4,604,000 4,389,000 4,971,000 4,572,000 5,617,000 5,326,000 4,111,000 3,123,000 2,071,000 2,496,000 2,054,000 1,703,000 1,519,000 1,421,000 1,657,000 1,164,000 846,000 1,034,000 1,168,000 818,000 460,000 751,000 521,000 257,000 354,000 
        commitments and contingencies
      		                                         
        accumulated other comprehensive income
      		                     -1,000 1,000  17,000  8,000 22,000 2,000             
        related party note payable, current
      		            801,000 917,000 98,000      118,000                     
        related party note payable, less current
      		            65,000,000 65,000,000 65,000,000      41,000,000                     
        deferred revenue
      		            4,000  38,000 32,000 16,000 16,000 7,000                       
        total stockholders’ deficit
      		            -10,668,000                             
        note payable, current
      		                 436,000 1,086,000 1,730,000                      
        total stockholders’ (deficit) equity
      		             -2,248,000                            
        lease liability, less current
      		              9,383,000 9,618,000 9,833,000  10,242,000 10,445,000 10,632,000  10,991,000  6,690,000   3,724,000 1,223,000             
        common stock
      		              37,000 37,000 29,000  29,000 29,000 26,000  25,000 25,000 21,000  21,000 21,000 21,000  17,000 17,000 17,000  16,000 15,000 14,000  13,000 13,000 8,000 
        accumulated other comprehensive loss
      		                         4,000        -51,000        
        investments
      		                     8,012,000 22,516,000  8,022,000 18,499,000 24,928,000 31,862,000 44,265,000 8,480,000 14,690,000 20,705,000 22,708,000 34,683,000 9,618,000 13,409,000 16,109,000  14,085,000 495,000  
        related party other receivable
      		                   8,371,000                      
        deferred rent, current
      		                             415,000 410,000 406,000 401,000 397,000 392,000 303,000      
        deferred rent, net of current
      		                                         
        lease liability
      		                         6,719,000                
        lease liability, net of current
      		                          3,674,000               
        other asset
      		                           1,645,000 208,000 101,000 101,000 101,000 101,000 101,000 101,000 101,000      
        deferred rent, less current
      		                             1,198,000 1,304,000 1,410,000 1,512,000         
        deferred rent
      		                                 1,613,000 1,715,000 1,816,000      
        intangible assets, net of accumulated amortization
      		                                  6,044,000 6,210,000 6,377,000 6,543,000 6,709,000 6,876,000 7,042,000 
        equipment, net of accumulated depreciation
      		                                    293,000 317,000 323,000 344,000 346,000 
        marketable investments
      		                                     14,306,000    
        deferred offering costs
      		                                        493,000 
        accumulated comprehensive loss
      		                                         
        cash
      		                                        2,105,000 
      Cashflow Statements:
      Quarterly
      Annual
        Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-09-30 2022-06-30 2022-03-31 2021-09-30 2021-06-30 2021-03-31 2020-09-30 2020-06-30 2020-03-31 2019-09-30 2019-06-30 2019-03-31 2018-09-30 2018-06-30 2018-03-31 2017-09-30 2017-06-30 2017-03-31 2016-09-30 2016-06-30 2016-03-31 
                                          
          cash flows from operating activities
        		                                  
          net loss
        		-18,581,000 -17,433,000 -19,385,000 -19,168,000 -16,795,000 -19,385,000 -12,680,000 -11,383,000 -10,137,000 -11,933,000 -10,566,000 -9,910,000 -9,801,000 -49,308,000 -31,269,000 -17,273,000 -48,244,000 -33,962,000 -18,639,000 -36,101,000 -23,205,000 -11,872,000 -33,183,000 -21,437,000 -10,078,000 -28,592,000 -17,831,000 -8,668,000 -16,864,000 -9,378,000 -3,198,000 -6,709,000 -3,942,000 -1,684,000 
          adjustments to reconcile net loss to net cash from operating activities:
        		                                  
          depreciation
        		88,000 93,000 90,000 106,000 117,000 121,000 127,000 132,000 132,000 138,000 133,000 136,000 135,000 520,000 347,000 160,000 349,000 229,000 113,000 310,000 213,000 104,000 390,000 300,000 162,000 474,000 309,000 153,000       
          amortization of intangible assets
        		167,000 166,000 166,000 167,000 166,000 166,000 167,000 166,000 167,000 166,000 166,000 166,000 167,000 499,000 333,000 166,000 500,000 333,000 167,000 499,000 333,000 166,000 500,000 333,000 167,000 499,000 333,000 166,000 499,000 333,000 166,000 499,000 332,000 166,000 
          stock-based compensation
        		1,912,000 4,970,000 5,617,000 5,189,000 5,681,000 6,793,000 2,982,000 2,052,000 1,759,000 3,344,000 1,798,000 1,143,000 896,000 4,443,000 3,720,000 2,007,000 10,990,000 9,413,000 6,965,000 7,686,000 5,038,000 2,626,000 7,739,000 5,060,000 2,361,000 9,988,000 6,595,000 3,420,000 6,403,000 3,053,000 263,000 627,000 389,000 193,000 
          non-cash lease expense
        		308,000 306,000 291,000                                
          write-off of deferred issuance costs
        		281,000                                  
          other
        		62,000                                  
          changes in operating assets and liabilities:
        		                                  
          accounts receivable
        		55,000 -259,000            56,000 53,000 40,000 -72,000                  
          inventory
        		-70,000 -79,000 -6,000 -21,000 -30,000         -2,297,000 -2,047,000 -1,663,000 -4,281,000 -2,691,000 -1,135,000                
          prepaid expenses and other current assets
        		-129,000 -374,000 -115,000 -149,000 -274,000 -9,000 -312,000 -89,000 7,000 278,000 -34,000 -469,000 160,000 940,000 1,112,000 191,000 -2,087,000 -2,454,000 -124,000 431,000 522,000 460,000 -658,000 -1,129,000 229,000 -683,000 -749,000 44,000 -244,000 -449,000 15,000 -250,000 -293,000  
          other non-current assets
        		3,000                                  
          accounts payable
        		-148,000 -186,000 274,000 332,000 712,000 -7,000 92,000 -162,000 -124,000 437,000 -386,000 -375,000 587,000 -895,000 -931,000 609,000 975,000 1,041,000 433,000 -595,000 -758,000 -749,000 544,000 305,000 -72,000 499,000 720,000 162,000 649,000 586,000 517,000 184,000 71,000 34,000 
          accrued liabilities
        		1,832,000                                  
          lease liabilities
        		-375,000 -360,000 -355,000 -332,000 -321,000 -299,000 -276,000 -254,000 -247,000 -240,000 -235,000 -214,000 -207,000 -573,000 -369,000 -182,000 -365,000 -192,000 -95,000 -104,000 -110,000 69,000             
          net cash from operating activities
        		-14,595,000 -14,755,000 -13,039,000 -12,807,000 -13,521,000 -9,144,000 -9,024,000 -8,395,000 -9,780,000 -6,782,000 -10,487,000 -9,202,000 -6,570,000 -39,048,000 -28,416,000 -15,594,000 -41,403,000 -28,053,000 -11,687,000 -26,110,000 -17,561,000 -9,622,000 -24,989,000 -17,024,000 -7,330,000 -17,588,000 -10,738,000 -5,018,000 -7,124,000 -3,707,000 -2,499,000 -5,733,000 -3,751,000 -1,462,000 
          capital expenditures
        		-33,000 -105,000 -62,000 -103,000 -45,000 -53,000 -38,000 -29,000 -5,000 -43,000 -23,000 -16,000 -39,000 -360,000 -298,000 -279,000 -303,000 -146,000 -51,000 -162,000 -100,000 -171,000 -645,000 -112,000 -45,000 -243,000 -171,000 -34,000 -2,407,000 -2,464,000 0 0 0 0 
          free cash flows
        		-14,628,000 -14,860,000 -13,101,000 -12,910,000 -13,566,000 -9,197,000 -9,062,000 -8,424,000 -9,785,000 -6,825,000 -10,510,000 -9,218,000 -6,609,000 -39,408,000 -28,714,000 -15,873,000 -41,706,000 -28,199,000 -11,738,000 -26,272,000 -17,661,000 -9,793,000 -25,634,000 -17,136,000 -7,375,000 -17,831,000 -10,909,000 -5,052,000 -9,531,000 -6,171,000 -2,499,000 -5,733,000 -3,751,000 -1,462,000 
          cash flows from investing activities:
        		                                  
          purchases of property and equipment
        		-33,000 -105,000 -62,000 -103,000 -45,000 -53,000 -38,000 -29,000 -5,000 -43,000 -23,000 -16,000 -39,000 -360,000 -298,000 -279,000 -303,000 -146,000 -51,000 -162,000 -100,000 -171,000 -645,000 -112,000 -45,000 -243,000 -171,000 -34,000 -2,407,000 -2,464,000     
          net cash from investing activities
        		-33,000 -105,000 -62,000 -123,000 -45,000 -53,000 -38,000 -29,000 -5,000 -43,000 -23,000 -16,000 -39,000 -360,000 -298,000 -279,000 7,697,000 7,854,000 7,949,000 -4,168,000 18,404,000  -16,626,000 -23,180,000  19,898,000    -1,578,000 -1,810,000 -14,160,000 -556,000 -39,000 
          cash flows from financing activities:
        		                                  
          proceeds from issuance of common stock under employee stock purchase plan
        		465,000 -7,000 241,000 0 352,000 0 182,000 0 296,000 0 103,000 1,000 291,000 485,000 372,000 372,000 810,000 421,000 430,000 490,000 255,000 255,000 423,000 222,000 272,000          
          proceeds from exercises of warrants, net of issuance costs
        		130,000 1,000 17,000                                
          proceeds from exercises of stock options
        		1,674,000 387,000 1,708,000 12,000 380,000 373,000 476,000 13,000 9,000 804,000 309,000      678,000 678,000 619,000 349,000 9,000 9,000 272,000 272,000 222,000 423,000 164,000 112,000 200,000 170,000 6,000    
          payment of deferred issuance costs in relation to registration statements
        		-57,000                                  
          net cash from financing activities
        		2,212,000 381,000 1,966,000 0 14,807,000 48,202,000 61,899,000 -265,000 305,000 804,000 2,149,000 13,867,000 -432,000 79,956,000 14,898,000 -65,000 63,234,000 55,162,000 51,158,000 30,449,000 30,023,000 264,000 82,000 -119,000 494,000 635,000 237,000 300,000 35,194,000 5,186,000 4,971,000 20,915,000 20,915,000  
          net increase in cash and cash equivalents
        		-12,416,000 -14,479,000   1,241,000 39,005,000    -6,021,000    40,548,000 -13,816,000 -15,938,000 29,528,000      -41,533,000 -40,323,000  2,945,000 3,408,000        
          cash and cash equivalents at beginning of period
        		80,735,000 0 0 0 118,038,000 0 0 0 44,365,000 0 0 0 61,139,000 28,614,000 28,614,000 28,614,000 12,463,000 12,463,000 12,463,000 6,899,000 6,899,000 6,899,000 51,103,000 51,103,000 51,103,000 3,386,000 3,386,000 3,386,000 2,089,000 2,089,000 2,089,000 3,606,000 3,606,000  
          cash and cash equivalents at end of period
        		68,319,000 -14,479,000 -11,135,000 -12,930,000 119,279,000 39,005,000 52,837,000 -8,689,000 34,885,000 -6,021,000 -8,361,000 4,649,000 54,098,000 69,162,000 14,798,000 12,676,000 41,991,000 47,426,000 59,883,000 7,070,000 37,765,000 7,864,000 9,570,000 10,780,000 8,536,000 6,331,000 6,794,000 10,667,000 32,423,000 1,990,000 2,751,000 4,628,000 20,214,000  
          supplemental disclosure of noncash investing and financing activities:
        		                                  
          proceeds from exercise of warrants and stock options not yet received
        		88,000                                  
          unpaid issuance costs in relation to registration statements
        		111,000                                  
          unpaid amounts related to purchase of equipment
        		28,000                                  
          unpaid warrant issuance costs
        		3,000                                  
          cash flows from operating activities:
        		                                  
          loss on disposal of fixed assets
        		                   119,000 119,000              
          purchases of intangible assets
        		 0 0                                
          proceeds from issuance of common stock and warrants in relation to rights offering, net of issuance costs
        		     0                             
          payment of deferred issuance costs in relation to at-the-market equity offering program
        		                                  
          rights offering deemed pro-rata distribution to shareholders
        		     0 0                            
          right-of-use asset obtained in exchange for lease liability
        		                                  
          other receivables
        		  0 -7,000 -7,000 41,000 4,000 10,000 -7,000 -5,000 8,000 107,000 -1,000 -53,000 -30,000 -39,000 32,000 23,000 48,000                
          other long-term assets
        		    -1,000               129,000 129,000 -68,000   -107,000          
          accrued expenses
        		  427,000 793,000 -3,043,000 3,205,000 642,000 911,000 -1,546,000 810,000 170,000 -257,000 496,000 -407,000 296,000 215,000 -355,000 -754,000 291,000 1,352,000 393,000 -425,000 633,000 282,000 98,000 623,000 130,000 -188,000 207,000 67,000 -291,000 56,000 -141,000 -44,000 
          issuance costs in relation to at-the-market equity offering
        		                                  
          equipment purchases included in accounts payable and accrued expenses
        		     13,000 -3,000    3,000   -16,000 -27,000 -27,000 14,000 65,000                 
          issuance costs in accounts payable and accrued expenses
        		  0                                
          other receivable from exercises of warrants
        		                                  
          issuance cost in relation to rights offering
        		                                  
          net decrease in cash and cash equivalents
        		       -8,689,000 -9,480,000   4,649,000 -7,041,000                      
          equipment purchases included in accounts payable
        		   50,000 -26,000                              
          right-of-use assets
        		    274,000 255,000 230,000 222,000 216,000 210,000 204,000 199,000 193,000 535,000 352,000 174,000 484,000 319,000 158,000 352,000 198,000 71,000             
          proceeds from exercises of warrants
        		    14,075,000 47,888,000    0 -7,000 14,641,000 194,000 15,000   4,217,000 4,217,000 4,217,000 112,000               
          warrant issuance costs in accounts payable
        		    11,000                              
          accrued interest on related party note payable
        		         0 -1,745,000 276,000 801,000 98,000                     
          issuance cost in relation to related party note extinguishment
        		         0 -1,000                        
          deferred issuance costs in relation to future at-the-market equity offering
        		     -59,000                             
          principal and accrued interest of related party note settled via issuance of common stock
        		         -130,498,000 1,000                        
          other receivable from exercise of warrants
        		                                  
          rights offering and warrant issuance costs in accounts payable and accrued expenses
        		                                  
          rights offering and at-the-market issuance costs in accounts payable
        		                                  
          payments made on related party note
        		           -828,000 -917,000                      
          issuance costs in relation to future rights offering
        		                                  
          deferred revenue
        		            4,000 22,000 16,000  7,000                  
          write-off of excessive and obsolete inventory
        		                                  
          accrued interest on note payable
        		             1,000 1,000 1,000 651,000                  
          proceeds from issuance of common stock
        		             14,893,000 14,963,000  56,697,000 48,348,000           34,944,000 4,965,000     
          proceeds from issuance of related party note
        		             65,000,000     41,000,000                
          payments made on insurance loan agreement
        		             -437,000 -437,000 -437,000 -875,000                  
          other receivable from issuance of common stock
        		              13,000                    
          net premium amortization and discount on available-for-sale securities
        		                13,000 13,000 13,000 -6,000 -1,000    -96,000          
          gain on u.s. treasury securities
        		                   -8,000               
          purchases of investments
        		                   -25,516,000 -3,006,000 -3,006,000 -72,981,000 -55,068,000 -44,186,000 -39,799,000 -29,110,000 -19,157,000 -11,363,000 -11,363,000     
          maturities of investments
        		                8,000,000 8,000,000 8,000,000 4,510,000 17,000,000 13,500,000 57,000,000 32,000,000 8,500,000 35,065,000 18,315,000 6,315,000 16,034,000 12,249,000 5,800,000    
          sales of investments
        		                   17,000,000      24,875,000 24,875,000 24,875,000       
          proceeds from insurance loan agreement
        		                1,939,000 1,730,000                 
          tax payments related to shares withheld for vested restricted stock units
        		                -232,000 -232,000     -613,000 -613,000  -115,000 -115,000        
          other receivable from exercise of warrants and stock options
        		                                  
          change in unrealized gains on available-for-sale securities
        		                1,000 1,000 1,000 -3,000 -4,000 13,000 9,000 23,000 3,000 48,000 51,000 48,000       
          accrued interest settled via issuance of common stock from private placement equity offering
        		                                  
          reserve for excessive and obsolete inventory
        		             7,371,000                     
          issuance costs for rights offering in accounts payable
        		             -29,000      64,000 261,000              
          related party other receivable from issuance of common stock from private placement equity offering
        		                 8,371,000                 
          issuance costs for rights offering in accounts payable and accrued expenses
        		              -74,000                    
          other receivable from issuance of common stock from at-the-market equity offering
        		                 25,000 -71,000                
          adjustments to reconcile net loss to net cash from ‎ operating activities:
        		                                  
          supplemental disclosure of noncash investing ‎ and financing activities:
        		                                  
          other assets
        		                   -174,000 -424,000  -2,734,000            
          sale of investments
        		                    4,510,000              
          accrued interest settled via issuance of common stock from private placement equity offering from private placement equity offering
        		                629,000 629,000                 
          accrued interest on related party note
        		                 629,000 118,000                
          net increase in cash
        		                 34,963,000 47,420,000 171,000 30,866,000 965,000   -42,567,000   7,281,000 30,334,000 -99,000 662,000 1,022,000 16,608,000  
          proceeds from issuance of common stock from at-the-market equity offering
        		                  4,892,000                
          unpaid property and equipment included in accounts payable and accrued expenses
        		                  14,000 263,000 257,000              
          depreciation and amortization
        		                            196,000      
          other current and non-current liabilities
        		                      2,238,000            
          proceeds from exercises of stock options and warrants
        		                                  
          proceeds from issuance of common stock from rights offering
        		                                  
          other current and long-term liabilities
        		                       2,279,000 6,000          
          proceeds from issuance of common stock, net of issuance cost of 565
        		                   29,498,000               
          gain on government securities
        		                    -8,000              
          proceeds from the issuance of common stock and warrants, net of issuance cost of 501
        		                    29,759,000              
          net cash from (used) in investing activities
        		                     10,323,000   -35,731,000  13,909,000 11,999,000 2,264,000      
          landlord incentive for tenant improvements
        		                            2,119,000      
          proceeds from issuance of common stock from private placements, net of issuance costs of 199
        		                                  
          proceeds from issuance of common stock from rights offering, net of issuance costs of 213
        		                                  
          net premium amortization on investments
        		                      -458,000 -291,000  -100,000 -51,000 -10,000 24,000 14,000 5,000 3,000   
          equipment purchased in accounts payable and accrued expenses
        		                      219,000   39,000         
          other asset
        		                       -2,726,000     -101,000 -101,000     
          deferred rent
        		                         -296,000 -194,000 -97,000 -12,000      
          purchase of investments
        		                              -7,610,000 -14,096,000 -495,000  
          proceeds from issuance of common stock from initial public offering, net of issuance costs of 2,711
        		                                  
          reclassification of deferred offering costs to additional paid-in capital upon initial public offering
        		                               627,000 560,000  
          equipment purchased in accrued expenses
        		                            109,000      
          proceeds from issuance of common stock under employee stock plan
        		                         327,000 188,000 188,000       
          financing costs not yet paid
        		                            101,000      
          net premium amortization on available-for-sale securities
        		                                  
          change in deferred income taxes
        		                                  
          deferred offering costs
        		                               -213,000 -213,000 -146,000 
          deferred grant revenue
        		                                  
          purchase of available-for-sale securities
        		                                  
          maturities of available-for-sale securities
        		                                  
          proceeds from issuance of common stock from private placements, net of issuance costs
        		                                  
          proceeds from issuance of common stock from initial public offering, net of issuance costs
        		                               20,915,000 20,915,000  
          proceeds from exercise of warrants
        		                            50,000 51,000     
          depreciation of equipment
        		                             49,000 24,000 70,000 46,000 22,000 
          deferred rent/landlord incentive for tenant improvements
        		                             2,119,000     
          purchase of equipment
        		                               -64,000 -61,000 -39,000 
          proceeds from issuance of common stock from private offering, net of issuance costs
        		                              4,965,000    
          net premium amortization on marketable investments
        		                                  
          cash acquired in connection with acquisition of businesses
        		                                  
          purchase of marketable investments
        		                                  
          maturities of marketable investments
        		                                  
          common stock issued to founders
        		                                  
          net proceeds from private placement
        		                                  
          fair value of common stock issued in connection with license agreement
        		                                  
          fair value of common stock issued in connection with acquisition of businesses
        		                                  
          deferred income taxes
        		                                  
          net income
        		                                  
          adjustments to reconcile net income to net cash from operating activities:
        		                                  
          net decrease in cash
        		                                 -1,501,000 
          cash at beginning of period
        		                                 3,606,000 
          cash at end of period
        		                                 2,105,000