OPK Stock Balance Sheets

OPKO Health Quarterly Balance Sheets Chart

Quarterly

Annual

Goodwill

Account Receivables

Cash and Cash Eq

Account Payables

Inventory

OPKO Health Quarterly Balance Sheets Table

Quarterly

Annual

Unit: USD	2025-06-30	2025-03-31	2024-09-30	2024-06-30	2024-03-31	2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-09-30	2019-06-30	2019-03-31	2018-09-30	2018-06-30	2018-03-31	2017-09-30	2017-06-30	2017-03-31	2016-09-30	2016-06-30	2016-03-31	2015-09-30	2015-06-30	2015-03-31	2014-09-30	2014-06-30	2014-03-31	2013-12-31	2013-09-30	2013-06-30	2013-03-31	2012-12-31	2012-09-30	2012-06-30	2012-03-31	2011-12-31	2011-09-30	2011-06-30	2011-03-31	2010-12-31

assets
current assets:
cash, cash equivalents and current restricted cash	271,718,000	435,999,000	406,400,000
accounts receivable	99,376,000	96,150,000	106,579,000	105,313,000	111,367,000	123,379,000	117,449,000	210,982,000	121,486,000	127,312,000	123,188,000	158,425,000	212,755,000	259,637,000	255,192,000	265,856,000	320,462,000	286,314,000	241,544,000	214,352,000	132,476,000	140,765,000	148,287,000	144,383,000	157,374,000	152,777,000	158,642,000	233,916,000	251,747,000	238,893,000	223,827,000	213,372,000	204,479,000	189,725,000	26,980,000	19,064,000	21,210,000	23,113,000	19,664,000	19,767,000	21,372,000	22,227,000	21,170,000	21,162,000	19,142,000	15,901,000	16,249,000	12,544,000	12,688,000	15,528,000	14,001,000	13,317,000
inventory	66,345,000	64,001,000	59,408,000	60,153,000	59,366,000	65,697,000	68,960,000	73,749,000	75,411,000	74,060,000	71,429,000	83,306,000	99,406,000	86,502,000	112,861,000	134,722,000	159,104,000	132,341,000	111,873,000	72,965,000	58,697,000	50,109,000	48,293,000	44,610,000	43,379,000	46,753,000	49,815,000	46,954,000	48,293,000	47,492,000	43,186,000	42,046,000	40,575,000	40,693,000	20,519,000	18,324,000	16,662,000	18,334,000	18,865,000	18,079,000	19,516,000	19,778,000	23,022,000	22,261,000		17,087,000	18,393,000	13,339,000	10,516,000	16,326,000	18,137,000	19,957,000
other current assets and prepaid expenses	58,883,000	54,441,000	57,249,000	32,288,000	24,652,000	24,519,000	32,209,000	40,950,000	98,691,000	39,962,000	38,516,000	42,563,000	23,274,000	27,170,000	40,858,000	47,627,000	29,980,000	32,313,000	38,398,000	51,125,000	48,754,000	37,301,000	36,533,000	38,994,000	45,346,000	41,651,000	40,946,000	49,324,000	41,946,000	42,495,000	90,408,000	78,506,000
assets held for sale	87,011,000	87,013,000		119,651,000	120,279,000								316,353,000	314,994,000		33,067,000
total current assets	583,333,000	737,604,000	629,636,000	357,981,000	391,303,000	309,476,000	357,239,000	433,789,000	406,418,000	394,525,000	413,971,000	494,752,000	754,069,000	823,013,000	557,510,000	547,029,000	599,049,000	523,179,000	428,109,000	360,054,000	274,457,000	292,842,000	344,228,000	435,237,000	289,817,000	321,562,000	349,346,000	430,556,000	472,516,000	459,932,000	502,067,000	505,573,000	453,532,000	517,416,000	278,339,000	394,025,000	163,148,000	183,010,000	205,272,000	242,728,000	241,277,000	230,116,000	237,683,000	78,657,000	87,985,000	92,346,000	99,411,000	99,582,000	117,629,000	127,628,000	142,785,000	54,072,000
property, plant and equipment	74,937,000	71,195,000	72,271,000	66,766,000	64,165,000	75,429,000	78,170,000	78,876,000	80,853,000	82,879,000	79,949,000	78,601,000	81,899,000	79,727,000	107,500,000	106,652,000	139,069,000	140,554,000	134,102,000	130,540,000	127,304,000	128,519,000	137,106,000	139,965,000	147,386,000	150,156,000	148,718,000	142,437,000	133,355,000	126,256,000	125,486,000	128,274,000	133,948,000	126,822,000
intangible assets	555,988,000	568,518,000	641,396,000	659,111,000	680,034,000	740,283,000	758,414,000	782,195,000	803,616,000	823,520,000	835,136,000	862,409,000	890,498,000	321,683,000	433,855,000	445,515,000	456,309,000	475,002,000	486,418,000	499,125,000	513,511,000	564,310,000	581,306,000	597,316,000	631,434,000	648,541,000	667,637,000	714,552,000	731,134,000	746,654,000	781,890,000	804,445,000	625,405,000	660,287,000	94,247,000	59,432,000	65,553,000	69,059,000	71,921,000	74,533,000	77,333,000	79,775,000	82,354,000	95,784,000	82,586,000	75,835,000	75,094,000	76,730,000	14,252,000	18,545,000	19,355,000	9,964,000
in-process research and development	195,000,000	195,000,000	195,000,000	195,000,000	195,000,000	195,000,000	195,000,000	195,000,000	195,000,000	195,000,000	195,000,000	195,000,000		590,200,000	590,200,000	590,200,000	590,200,000	590,200,000	590,200,000	590,200,000	590,200,000	635,000,000	635,569,000	635,561,000	646,339,000	645,714,000	646,386,000	648,377,000	645,957,000	645,058,000	646,970,000	606,035,000	793,626,000	812,723,000	812,446,000	793,000,000	793,214,000	793,326,000	793,339,000	793,341,000	793,312,000	203,052,000	203,030,000
goodwill	484,185,000	476,672,000	535,868,000	530,106,000	530,615,000	598,260,000	594,457,000	597,375,000	597,380,000	595,851,000	573,499,000	578,845,000	519,052,000	520,601,000	674,574,000	677,360,000	676,162,000	680,602,000	675,795,000	671,599,000	669,582,000	695,798,000	699,842,000	698,522,000	713,629,000	714,234,000	719,891,000	715,573,000	712,075,000	705,990,000	700,526,000	691,060,000	746,961,000	761,234,000	289,607,000	223,219,000	224,769,000	226,001,000	226,062,000	226,373,000	222,340,000	82,086,000	82,709,000	80,450,000	49,738,000	40,988,000	40,319,000	39,815,000	6,234,000	6,853,000	6,672,000	5,856,000
investments	13,045,000	12,750,000	100,609,000	101,489,000	40,990,000	16,082,000	19,377,000	27,783,000	41,231,000	28,080,000	77,804,000	108,685,000	9,472,000	10,729,000	11,753,000	8,945,000	10,410,000	15,731,000	14,325,000	26,260,000	10,669,000	11,695,000	24,767,000	32,297,000	42,737,000	45,497,000	41,289,000	32,196,000	34,495,000	37,285,000	38,783,000	34,249,000	35,212,000	34,695,000	21,434,000	22,380,000	26,849,000	33,428,000	35,697,000	30,653,000	24,690,000	26,690,000	28,546,000	15,636,000	14,998,000	14,826,000	10,136,000	6,717,000	5,862,000	4,240,000	4,691,000	5,114,000
operating lease right-of-use assets	46,627,000	47,819,000	62,812,000	61,622,000	63,331,000	68,088,000	44,690,000	34,938,000	36,832,000	38,725,000	39,790,000	42,412,000	42,768,000	44,228,000	33,502,000	36,349,000	38,631,000	37,735,000	36,485,000	38,469,000	39,793,000	35,826,000	29,640,000	33,277,000
other assets	19,874,000	18,769,000	18,511,000	7,796,000	8,578,000	9,080,000	9,333,000	8,943,000	8,340,000	8,679,000	9,636,000	8,898,000	9,100,000	9,534,000	8,744,000	9,600,000	9,745,000	10,060,000	5,857,000	7,487,000	7,026,000	5,528,000	3,770,000	3,126,000	9,652,000	5,246,000	5,627,000	38,299,000	39,162,000	38,893,000	4,305,000	4,385,000	4,522,000		6,013,000	5,073,000	4,673,000	4,910,000	6,520,000	6,861,000	7,003,000	2,784,000	2,863,000	2,777,000	1,870,000	1,244,000	1,267,000	1,287,000	824,000	60,000	33,000	111,000
total assets	1,972,989,000	2,128,327,000	2,256,103,000	1,979,871,000	1,974,016,000	2,011,698,000	2,056,680,000	2,158,899,000	2,169,670,000	2,167,259,000	2,224,785,000	2,369,602,000	2,306,858,000	2,399,715,000	2,417,638,000	2,421,650,000	2,519,575,000	2,473,063,000	2,371,291,000	2,323,734,000	2,232,542,000	2,369,518,000	2,456,228,000	2,575,301,000	2,480,994,000	2,530,950,000	2,578,894,000	2,721,990,000	2,768,694,000	2,760,068,000	2,800,027,000	2,774,021,000	2,793,206,000	3,015,853,000	1,525,491,000	1,512,249,000	1,295,242,000	1,327,082,000	1,355,692,000	1,391,516,000	1,382,982,000	641,080,000	653,935,000	289,830,000	250,022,000	230,471,000	231,570,000	229,489,000	151,001,000	160,419,000	176,307,000	77,846,000
liabilities and equity
current liabilities:
accounts payable	56,683,000	59,370,000	62,721,000	82,242,000	71,157,000	69,677,000	66,801,000	87,877,000	80,503,000	66,993,000	49,748,000	56,107,000	94,240,000	82,040,000	94,393,000	88,512,000	162,690,000	100,883,000	65,685,000	44,671,000	55,866,000	77,296,000	60,376,000	51,085,000	65,613,000	69,061,000	64,229,000	66,536,000	62,153,000	74,558,000	58,544,000	61,062,000	73,436,000	77,969,000	16,039,000	10,472,000	8,841,000	10,041,000	14,696,000	13,414,000	13,631,000	11,646,000	11,287,000	10,200,000	7,238,000	4,402,000	4,877,000	4,891,000	2,556,000	2,890,000	4,574,000	7,170,000
accrued expenses	90,555,000	113,209,000	122,806,000	94,516,000	88,772,000	90,086,000	92,368,000	98,604,000	106,058,000	98,269,000	112,015,000	128,254,000	157,316,000	193,493,000	163,926,000	187,172,000	213,119,000	240,869,000	248,422,000	210,111,000	164,939,000	172,734,000	198,382,000	217,534,000	214,907,000	200,992,000	217,133,000	176,300,000	206,403,000	178,866,000	186,076,000	209,848,000	182,342,000	201,113,000	149,843,000	158,763,000	55,554,000	54,964,000	58,772,000	65,874,000	43,269,000	31,045,000	26,673,000	24,656,000	21,794,000	12,650,000	10,389,000	4,956,000	3,678,000	4,033,000	5,557,000	5,739,000
current maturities of operating leases	9,919,000	9,888,000	12,741,000	11,624,000	11,742,000	12,996,000	11,267,000	11,240,000	11,490,000	11,628,000	11,535,000	12,122,000	11,690,000	11,624,000	9,823,000	10,102,000	10,305,000	9,028,000	9,080,000	10,298,000	11,480,000	12,921,000	13,376,000	15,123,000
current portion of convertible notes		101,242,000	170,000	170,000	170,000					3,050,000	70,632,000
current portion of lines of credit and notes payable	14,024,000	12,145,000	13,222,000	22,129,000	22,820,000	27,293,000	30,118,000	28,729,000	24,371,000	33,540,000	23,342,000	18,989,000	17,412,000	14,695,000	14,893,000	17,961,000	17,816,000	24,703,000	12,702,000	14,463,000	12,802,000	7,187,000	11,240,000	112,316,000	6,353,000	6,465,000	6,971,000	16,112,000	14,496,000	11,527,000	9,891,000	10,327,000	11,454,000	78,508,000	14,599,000	13,603,000	12,446,000	14,397,000	11,032,000	12,562,000	14,477,000	16,778,000	20,264,000	17,526,000	17,408,000	14,571,000	14,194,000	8,757,000				14,690,000
total current liabilities	171,181,000	295,854,000	211,660,000	219,553,000	204,338,000	200,052,000	200,554,000	226,450,000	222,422,000	213,480,000	267,272,000	215,472,000	309,170,000	330,008,000	283,035,000	303,980,000	403,930,000	375,483,000	335,889,000	279,543,000	245,087,000	270,138,000	283,374,000	396,058,000	317,830,000	306,861,000	318,077,000	258,948,000	283,052,000	264,951,000	254,511,000	281,237,000	267,232,000	357,590,000	180,481,000	182,838,000	76,841,000	79,402,000	84,500,000	91,850,000	71,377,000	59,469,000	58,224,000	52,382,000	46,441,000	31,710,000	29,705,000	18,778,000	20,241,000	21,527,000	24,683,000	27,599,000
operating lease liabilities	37,291,000	38,344,000	52,057,000	49,624,000	50,931,000	54,140,000	34,649,000	24,912,000	26,462,000	27,963,000	29,005,000	30,876,000	31,596,000	33,097,000	28,256,000	30,605,000	32,394,000	29,760,000	28,225,000	28,759,000	28,669,000	23,318,000	16,673,000	18,621,000
long term portion of convertible notes	80,466,000	77,226,000	178,695,000	175,942,000	323,108,000		213,285,000	212,299,000	211,328,000		141,815,000
senior secured notes	246,012,000	245,794,000	245,358,000
deferred tax liabilities	113,328,000	129,435,000	128,412,000	119,120,000	121,635,000	126,773,000	138,007,000	133,049,000	129,668,000	126,426,000	135,073,000	176,741,000	125,030,000	148,487,000	134,247,000	136,416,000	135,244,000	137,208,000	119,182,000	118,979,000	118,600,000	113,479,000	113,334,000	116,009,000	134,112,000	148,255,000	148,732,000	118,799,000	142,212,000	159,286,000	184,493,000	207,595,000	202,680,000	408,213,000
other long-term liabilities	27,807,000	30,011,000
total long-term liabilities	504,904,000	520,810,000	641,026,000	365,001,000	516,870,000	422,427,000	411,558,000	397,101,000	395,438,000	392,131,000	328,445,000	435,331,000	382,804,000	384,581,000	369,036,000	375,085,000	419,131,000	426,029,000	411,632,000	455,848,000	438,836,000	457,451,000	463,923,000	416,506,000	374,521,000	413,593,000	437,553,000	374,006,000	378,813,000	388,147,000	440,124,000	477,144,000	528,100,000	688,895,000	518,024,000	516,838,000	331,057,000	334,855,000	439,943,000	426,687,000	443,679,000	269,127,000	275,933,000
total liabilities	676,085,000	816,664,000	852,686,000	584,554,000	721,208,000	622,479,000	612,112,000	623,551,000	617,860,000	605,611,000	595,717,000	650,803,000	691,974,000	714,589,000	652,071,000	679,065,000	823,061,000	801,512,000	747,521,000	735,391,000	683,923,000	727,589,000	747,297,000	812,564,000	692,351,000	720,454,000	755,630,000	632,954,000	661,865,000	653,098,000	694,635,000	758,381,000	795,332,000	1,046,485,000	698,505,000	699,676,000	407,898,000	414,257,000	524,443,000	518,537,000	515,056,000	328,596,000	334,157,000	86,550,000	79,371,000	54,583,000	52,204,000	44,221,000	22,395,000	23,127,000	26,566,000	28,666,000
equity:
common stock - 0.01 par value, 1,250,000,000 shares authorized; 809,582,957 and 701,350,447 shares issued at june 30, 2025 and december 31, 2024, respectively	8,097,000
treasury stock	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,791,000	-1,911,000	-1,911,000	-1,911,000	-1,911,000	-3,645,000	-3,645,000	-4,051,000	-4,051,000	-4,051,000	-7,300,000	-7,362,000	-7,457,000	-7,457,000	-7,457,000	-7,457,000	-7,457,000	-8,092,000	-8,092,000	-8,092,000	-7,893,000	-7,893,000	-61,000	-61,000
additional paid-in capital	3,596,392,000	3,484,068,000	3,516,735,000	3,540,414,000	3,386,147,000	3,433,006,000	3,430,340,000	3,427,094,000	3,424,589,000	3,421,872,000	3,418,763,000	3,413,556,000	3,191,139,000	3,222,487,000	3,218,583,000	3,214,351,000	3,155,648,000	3,152,694,000	3,150,437,000	3,147,030,000	3,145,444,000	3,065,059,000	3,061,631,000	3,058,509,000	2,907,017,000	2,901,086,000	2,895,191,000	2,883,026,000	2,863,025,000	2,856,645,000	2,834,300,000	2,736,816,000	2,728,264,000	2,696,420,000	1,687,389,000	1,628,818,000	1,523,548,000	1,490,071,000	1,384,694,000	1,379,383,000	1,357,235,000	742,097,000	739,778,000	565,201,000	529,958,000	528,468,000	526,023,000	524,814,000	485,181,000	482,910,000	482,521,000	376,008,000
accumulated other comprehensive loss	-24,730,000	-45,006,000	-39,614,000	-46,652,000	-45,195,000	-38,030,000	-46,495,000	-36,942,000	-37,611,000	-43,323,000	-58,026,000	-49,171,000	-31,415,000	-30,495,000	-19,923,000	-9,932,000	-13,295,000	-4,225,000	-17,451,000	-25,752,000	-30,187,000	-28,774,000	-20,351,000	-23,229,000	-13,138,000	-13,004,000	-539,000	-5,422,000	-14,070,000	-24,953,000	-16,284,000	-23,431,000	-17,110,000
accumulated deficit	-2,281,064,000	-2,132,623,000	-2,079,037,000	-2,103,927,000	-2,093,622,000	-2,011,786,000	-1,945,303,000	-1,860,830,000	-1,841,190,000	-1,822,923,000	-1,737,692,000	-1,651,601,000	-1,549,951,000	-1,511,976,000	-1,438,202,000	-1,466,941,000	-1,450,755,000	-1,481,833,000	-1,514,131,000	-1,537,848,000	-1,571,551,000	-1,398,727,000	-1,336,720,000	-1,276,914,000	-1,109,049,000	-1,081,397,000	-1,075,197,000	-792,377,000	-745,935,000	-728,407,000	-716,294,000	-701,317,000	-716,849,000	-706,474,000	-834,721,000	-791,955,000	-621,872,000	-573,203,000	-547,727,000	-503,177,000	-486,377,000	-426,379,000	-422,985,000	-388,770,000	-388,222,000	-378,576,000	-368,333,000	-359,722,000	-378,125,000	-369,889,000	-364,128,000	-358,379,000
total shareholders’ equity	1,296,904,000	1,311,663,000	1,403,417,000	1,395,317,000	1,252,808,000	1,389,219,000	1,444,568,000	1,535,348,000	1,551,810,000	1,561,648,000	1,629,068,000	1,718,799,000	1,614,884,000	1,685,126,000	1,765,567,000	1,742,585,000	1,696,514,000	1,671,551,000	1,623,770,000	1,588,343,000	1,548,619,000	1,641,929,000	1,708,931,000	1,762,737,000	1,788,643,000	1,810,496,000	1,823,264,000	2,089,036,000	2,106,829,000	2,106,970,000	2,105,392,000	2,015,640,000	1,997,874,000	1,969,368,000	826,986,000	812,573,000	887,344,000	912,825,000	831,249,000	876,410,000	870,727,000	314,482,000	320,817,000	179,386,000	146,265,000	151,502,000	154,980,000	160,882,000	102,478,000	111,164,000	123,613,000	23,052,000
total liabilities and equity	1,972,989,000	2,128,327,000	2,256,103,000	1,979,871,000	1,974,016,000	2,011,698,000	2,056,680,000	2,158,899,000	2,169,670,000	2,167,259,000	2,224,785,000	2,369,602,000	2,306,858,000	2,399,715,000	2,417,638,000	2,421,650,000	2,519,575,000	2,473,063,000	2,371,291,000	2,323,734,000	2,232,542,000	2,369,518,000	2,456,228,000	2,575,301,000	2,480,994,000	2,530,950,000	2,578,894,000	2,721,990,000	2,768,694,000	2,760,068,000	2,800,027,000	2,774,021,000	2,793,206,000	3,015,853,000	1,525,491,000	1,512,249,000	1,295,242,000	1,327,082,000	1,355,692,000
common stock - 0.01 par value, 1,250,000,000 shares authorized; 701,406,697 and 701,350,447 shares issued at march 31, 2025 and december 31, 2024, respectively		7,015,000
other long-term liabilities, principally contract liabilities, contingent consideration and lines of credit			36,504,000	20,315,000	21,196,000	27,189,000	25,617,000	26,841,000	27,980,000	27,371,000	22,552,000	16,237,000	15,658,000	15,062,000	20,990,000	24,866,000	26,711,000	37,072,000
common stock - 0.01 par value, 1,250,000,000 shares authorized; 712,283,206 and 781,936,885 shares issued at september 30, 2024 and december 31, 2023, respectively			7,124,000
cash and cash equivalents				40,576,000	75,639,000	95,881,000	138,621,000	108,108,000	110,830,000	153,191,000	180,838,000	210,458,000	102,281,000	134,710,000	148,599,000	65,757,000	89,503,000	72,211,000	36,294,000	21,612,000	34,530,000	64,667,000	111,115,000	207,250,000	43,718,000	80,381,000	99,943,000	100,362,000	130,530,000	131,052,000	144,646,000	156,015,000	174,973,000	212,144,000	221,217,000	348,192,000	118,258,000	134,010,000	156,396,000	185,798,000	155,834,000	119,061,000	181,596,000	27,361,000	23,428,000	38,171,000	47,118,000	71,516,000	47,235,000	38,849,000	47,879,000	18,016,000
liabilities associated with assets held for sale				8,872,000	9,677,000									28,156,000
common stock - 0.01 par value, 1,250,000,000 shares authorized; 727,176,232 and 781,936,885 shares issued at june 30, 2024 and december 31, 2023, respectively				7,273,000
common stock - 0.01 par value, 1,000,000,000 shares authorized; 726,791,854 and 781,936,885 shares issued at march 31, 2024 and december 31, 2023, respectively					7,269,000
convertible notes						214,325,000				210,371,000		211,477,000	210,520,000	187,935,000	185,543,000	183,198,000	224,782,000	221,989,000	219,194,000	216,457,000	213,805,000	208,695,000	206,165,000	203,711,000
common stock - 0.01 par value, 1,000,000,000 shares authorized; 781,936,885 and 781,306,164 shares issued at december 31, 2023 and 2022, respectively						7,820,000
common stock - 0.01 par value, 1,000,000,000 shares authorized; 781,711,885 and 781,306,164 shares issued at september 30, 2023 and december 31, 2022, respectively							7,817,000
common stock - 0.01 par value, 1,000,000,000 shares authorized; 781,693,135 and 781,306,164 shares issued at june 30, 2023 and december 31, 2022, respectively								7,817,000
common stock - 0.01 par value, 1,000,000,000 shares authorized; 781,306,164 and 781,306,164 shares issued at march 31, 2023 and december 31, 2022, respectively									7,813,000
common stock - 0.01 par value, 1,000,000,000 shares authorized; 781,306,164 and 690,082,283 shares issued at december 31, 2022 and 2021, respectively										7,813,000
liabilities associated with assets held-for-sale													28,512,000			233,000
common stock - 0.01 par value, 1,000,000,000 shares authorized; 781,341,231 and 690,082,283 shares issued at september 30, 2022 and december 31, 2021, respectively											7,814,000
common stock - 0.01 par value, 1,000,000,000 shares authorized; 780,591,681 and 690,082,283 shares issued at june 30, 2022 and december 31, 2021, respectively												7,806,000
common stock - 0.01 par value, 1,000,000,000 shares authorized; 690,138,033 and 690,082,283 shares issued at march 31, 2022 and december 31, 2021, respectively													6,902,000
common stock - 0.01 par value, 1,000,000,000 shares authorized at december 31, 2021 and 2020, respectively; 690,082,283 and 670,585,576 shares issued at december 31, 2021 and 2020, respectively														6,901,000
common stock - 0.01 par value, 1,000,000,000 shares authorized; 689,996,658 and 670,585,576 shares issued at september 30, 2021 and december 31, 2020, respectively															6,900,000
common stock - 0.01 par value, 1,000,000,000 shares authorized; 689,817,971 and 670,585,576 shares issued at june 30, 2021 and december 31, 2020, respectively																6,898,000
common stock - 0.01 par value, 1,000,000,000 shares authorized; 670,703,076 and 670,585,576 shares issued at march 31, 2021 and december 31, 2020, respectively																	6,707,000
common stock - 0.01 par value, 1,000,000,000 shares authorized at december 31, 2020 and 2019, respectively; 670,585,576 and 670,378,701 shares issued at december 31, 2020 and 2019, respectively																		6,706,000
other long-term liabilities, principally contract liabilities, contingent consideration and line of credit																			45,031,000	91,653,000	77,762,000	111,959,000	127,751,000	78,165,000	183,812,000	209,444,000	233,622,000
common stock - 0.01 par value, 1,000,000,000 shares authorized; 670,550,201 and 670,378,701 shares issued at september 30, 2020 and december 31, 2019, respectively																			6,706,000
common stock - 0.01 par value, 1,000,000,000 shares authorized; 670,378,701 and 670,378,701 shares issued at june 30, 2020 and december 31, 2019, respectively																				6,704,000
common stock - 0.01 par value, 1,000,000,000 shares authorized; 670,378,701 and 670,378,701 shares issued at march 31, 2020 and december 31, 2019, respectively																					6,704,000
common stock - 0.01 par value, 1,000,000,000 and 750,000,000 shares authorized at september 30, 2019 and december 31, 2018, respectively; 616,150,952 and 586,881,720 shares issued at september 30, 2019 and december 31, 2018, respectively																						6,162,000
common stock - 0.01 par value, 1,000,000,000 and 750,000,000 shares authorized at june 30, 2019 and december 31, 2018, respectively; 616,150,952 and 586,881,720 shares issued at june 30, 2019 and december 31, 2018, respectively																							6,162,000
common stock - 0.01 par value, 750,000,000 shares authorized; 616,150,952 and 586,881,720 shares issued at march 31, 2019 and december 31, 2018, respectively																								6,162,000
current portion of 2033 senior notes																									30,957,000	30,343,000	29,744,000
2023 convertible notes and 2033 senior notes																									56,597,000	55,894,000	55,199,000
common stock - 0.01 par value, 750,000,000 shares authorized; 560,377,422 and 560,023,745 shares issued at september 30, 2018 and december 31, 2017, respectively																									5,604,000
common stock - 0.01 par value, 750,000,000 shares authorized; 560,169,422 and 560,023,745 shares issued at june 30, 2018 and december 31, 2017, respectively																										5,602,000
common stock - 0.01 par value, 750,000,000 shares authorized; 560,023,745 and 560,023,745 shares issued at march 31, 2018 and december 31, 2017, respectively																											5,600,000
2033 senior notes, net of discount																												28,590,000
other long-term liabilities, principally deferred revenue, contingent consideration and line of credit																												226,617,000	201,843,000
common stock - 0.01 par value, 750,000,000 shares authorized; 559,955,118 and 558,576,051 shares issued at september 30, 2017 and december 31, 2016, respectively																												5,600,000
2033 senior notes and estimated fair value of embedded derivatives, net of discount																													34,758,000	39,285,000	51,537,000	45,233,000	49,608,000
common stock - 0.01 par value, 750,000,000 shares authorized; 559,955,118 and 558,576,051 shares issued at june 30, 2017 and december 31, 2016, respectively																													5,600,000
other long-term liabilities, principally deferred revenue and line of credit																														189,576,000	204,094,000	224,316,000	275,812,000
common stock - 0.01 par value, 750,000,000 shares authorized; 559,597,843 and 558,576,051 shares issued at march 31, 2017 and december 31, 2016, respectively																														5,596,000
common stock - 0.01 par value, 750,000,000 shares authorized; 558,053,479 and 546,188,516 shares issued at september 30, 2016 and december 31, 2015, respectively																															5,581,000
marketable securities																																15,634,000									25,004,000	50,027,000			18,923,000	17,117,000	14,997,000		40,182,000	54,998,000	59,983,000
common stock - 0.01 par value, 750,000,000 shares authorized; 548,301,575 and 546,188,516 shares issued at june 30, 2016 and december 31, 2015, respectively																																5,483,000
prepaid expenses and other current assets																																	33,505,000	74,854,000	9,623,000	8,445,000	7,018,000	7,553,000	10,347,000	19,084,000	19,551,000	19,023,000	11,895,000	7,873,000	5,004,000	4,070,000	2,654,000	2,179,000	1,729,000	1,927,000	2,785,000	2,782,000
common stock - 0.01 par value, 750,000,000 shares authorized; 547,980,417 and 546,188,516 shares issued at march 31, 2016 and december 31, 2015, respectively																																	5,480,000
other assets, principally deferred tax assets																																		102,676,000
2033 senior notes, net of discount and estimated fair value of embedded derivatives																																		44,206,000	109,203,000	106,673,000	114,883,000	116,365,000	224,801,000
other long-term liabilities, principally deferred revenue and contingent consideration																																		236,476,000
common stock - 0.01 par value, 750,000,000 shares authorized; 545,951,707 and 433,421,677 shares issued at september 30, 2015 and december 31, 2014, respectively																																		5,459,000
accumulated other comprehensive income																																		-20,992,000	-18,880,000	-17,503,000	-8,697,000	304,000	1,399,000	3,418,000	3,237,000	2,830,000	8,093,000	7,356,000	9,004,000	6,722,000	2,406,000	907,000	434,000	3,157,000	2,424,000	2,921,000
total shareholders’ equity attributable to opko																																		1,970,768,000	834,789,000	819,902,000	893,257,000	917,392,000
noncontrolling interests																																		-1,400,000	-7,803,000	-7,329,000	-5,913,000	-4,567,000	-3,971,000	-3,431,000	-2,801,000	-1,998,000	-1,039,000	-492,000
property, plant, equipment, and investment properties																																			23,405,000	15,120,000	17,036,000	17,348,000	16,881,000	17,027,000	17,027,000	16,577,000		16,526,000
other long-term liabilities, principally deferred revenue and deferred tax liabilities																																			408,821,000	410,165,000
common stock - 0.01 par value, 750,000,000 shares authorized; 464,567,632 and 433,421,677 shares issued at june 30, 2015 and december 31, 2014, respectively																																			4,646,000
common stock - 0.01 par value, 750,000,000 shares authorized; 459,314,572 and 433,421,677 shares issued at march 31, 2015 and december 31, 2014, respectively																																				4,593,000
other long-term liabilities, principally contingent consideration and deferred tax liabilities																																					216,174,000	218,490,000	215,142,000	214,775,000	234,762,000	80,603,000	79,512,000	34,168,000	32,930,000	22,873,000	22,499,000	25,443,000
common stock - 0.01 par value, 750,000,000 shares authorized; 432,895,788 and 414,818,195 shares issued at september 30, 2014 and december 31, 2013, respectively																																					4,329,000
common stock - 0.01 par value, 750,000,000 shares authorized; 427,102,876 and 414,818,195 shares issued at june 30, 2014 and december 31, 2013, respectively																																						4,271,000
common stock - 0.01 par value, 750,000,000 shares authorized; 415,346,120 and 414,818,195 shares issued at march 31, 2014 and december 31, 2013, respectively																																							4,154,000
total shareholders’ equity attributable to parent																																							835,220,000
liabilities, series d preferred stock, and equity
3.00% convertible senior notes, net of discount and estimated fair value of embedded derivatives																																								211,912,000	208,917,000	188,524,000	196,421,000
commitments and contingencies:
series d preferred stock - 0.01 par value, 2,000,000 shares authorized; no shares issued or outstanding at december 31, 2013 and 1,129,032 shares issued and outstanding (liquidation value of 30,595) at december 31, 2012
series a preferred stock - 0.01 par value, 4,000,000 shares authorized; no shares issued or outstanding at december 31, 2013 or 2012
series c preferred stock - 0.01 par value, 500,000 shares authorized; no shares issued or outstanding at december 31, 2013 or 2012
common stock - 0.01 par value, 750,000,000 shares authorized; 414,818,195 and 305,560,763 shares issued at december 31, 2013 and 2012, respectively																																								4,148,000
total equity																																								872,979,000	867,926,000	312,484,000	319,778,000	178,894,000
total liabilities, series d preferred stock, and equity																																								1,391,516,000	1,382,982,000	641,080,000	653,935,000
series d preferred stock - 0.01 par value, 2,000,000 shares authorized; no shares issued or outstanding at september 30, 2013 and 1,129,032 shares issued and outstanding (liquidation value of 30,595) at december 31, 2012
series a preferred stock - 0.01 par value, 4,000,000 shares authorized; no shares issued or outstanding at september 30, 2013 or december 31, 2012
series c preferred stock - 0.01 par value, 500,000 shares authorized; no shares issued or outstanding at september 30, 2013 or december 31, 2012
common stock - 0.01 par value, 500,000,000 shares authorized; 408,903,912 and 305,560,763 shares issued at september 30, 2013 and december 31, 2012, respectively																																									4,089,000
series d preferred stock - 0.01 par value, 2,000,000 shares authorized; no shares issued or outstanding at june 30, 2013 and 1,129,032 shares issued and outstanding (liquidation value of 30,595) at december 31, 2012
series a preferred stock - 0.01 par value, 4,000,000 shares authorized; no shares issued or outstanding at june 30, 2013 and december 31, 2012, respectively
series c preferred stock - 0.01 par value, 500,000 shares authorized; no shares issued or outstanding at june 30, 2013 or december 31, 2012
common stock - 0.01 par value, 500,000,000 shares authorized; 339,045,029 and 305,560,763 shares issued at june 30, 2013 and december 31, 2012, respectively																																										3,391,000
current assets
property, equipment, and investment properties																																											16,750,000
current liabilities
commitments and contingencies
series d preferred stock - 0.01 par value, 2,000,000 shares authorized; no shares issued or outstanding at march 31, 2013 and 1,129,032 shares issued and outstanding (liquidation value of 30,595) at december 31, 2012
equity
series a preferred stock - 0.01 par value, 4,000,000 shares authorized; no shares issued or outstanding at march 31, 2013 and december 31, 2012, respectively
series c preferred stock - 0.01 par value, 500,000 shares authorized; no shares issued or outstanding at march 31, 2013 or december 31, 2012
common stock - 0.01 par value, 500,000,000 shares authorized; 338,828,976 and 305,560,763 shares issued at march 31, 2013 and december 31, 2012, respectively																																											3,388,000
current assets of discontinued operations																																																4,000	5,279,000
liabilities, series d preferred stock and equity
current liabilities of discontinued operations																																														87,000	245,000	174,000	1,460,000
series d preferred stock – 0.01 par value, 2,000,000 shares authorized; 1,129,032 and 1,129,032 shares issued and outstanding (liquidation value of 30,595 and 28,355) at december 31, 2012 and 2011, respectively																																												24,386,000
series a preferred stock – 0.01 par value, 4,000,000 shares authorized; no shares issued or outstanding at december 31, 2012 or 2011
series c preferred stock – 0.01 par value, 500,000 shares authorized; no shares issued or outstanding at december 31, 2012 or 2011
common stock – 0.01 par value, 500,000,000 shares authorized; 305,560,763 shares and 297,503,033 shares issued and outstanding at december 31, 2012 and 2011, respectively																																												3,056,000
total liabilities, series d preferred stock and equity																																												289,830,000
inventories																																													21,488,000
property and equipment																																													12,845,000	5,232,000	5,343,000	5,358,000	3,271,000	3,093,000	2,771,000	2,729,000
liabilities, series d preferred stock, and shareholders’ equity
current liabilities of discounted operations																																													1,000
series d preferred stock - 0.01 par value, 2,000,000 shares authorized; 1,129,032 shares and 1,129,032 shares issued and outstanding (liquidation value of 30,035 and 28,355) at september 30, 2012 and december 31, 2011, respectively																																													24,386,000
shareholders’ equity:
series a preferred stock - 0.01 par value, 4,000,000 shares authorized; no shares issued or outstanding at september 30, 2012 or december 30, 2011
series c preferred stock - 0.01 par value, 500,000 shares authorized; no shares issued or outstanding at september 30, 2012 or december 30, 2011
common stock - 0.01 par value, 500,000,000 shares authorized; 298,151,813 shares and 297,503,033 shares issued at september 30, 2012 and december 30, 2011, respectively																																													2,982,000
total liabilities, series d preferred stock, and shareholders’ equity																																													250,022,000	230,471,000	231,570,000	229,489,000	151,001,000	160,419,000	176,307,000
series d preferred stock - 0.01 par value, 2,000,000 shares authorized; 1,129,032 and 1,129,032 shares issued and outstanding (liquidation value of 29,475 and 28,355) at june 30, 2012 and december 31, 2011, respectively																																														24,386,000
series a preferred stock - 0.01 par value, 4,000,000 shares authorized; no shares issued or outstanding at june 30, 2012 and december 31, 2011
series c preferred stock - 0.01 par value, 500,000 shares authorized; no shares issued or outstanding at june 30, 2012 or december 31, 2011
common stock - 0.01 par value, 500,000,000 shares authorized; 297,991,402 and 297,503,033 shares issued at june 30, 2012 and december 31, 2011, respectively																																														2,980,000
series d preferred stock – 0.01 par value, 2,000,000 shares authorized; 1,129,032 and 1,129,032 shares issued and outstanding (liquidation value of 28,915 and 28,355) at march 31, 2012 and december 31, 2011, respectively																																															24,386,000
shareholders’ equity
series a preferred stock – 0.01 par value, 4,000,000 shares authorized; no shares issued or outstanding at march 31, 2012 and december 31, 2011, respectively
series c preferred stock – 0.01 par value, 500,000 shares authorized; no shares issued or outstanding at march 31, 2012 or december 31, 2011
common stock – 0.01 par value, 500,000,000 shares authorized; 297,552,819 and 297,503,033 shares issued at march 31, 2012 and december 31, 2011, respectively																																															2,976,000
series d preferred stock – 0.01 par value, 2,000,000 shares authorized; 1,129,032 and 1,209,677 shares issued and outstanding (liquidation value of 28,355 and 33,013) at december 31, 2011 and 2010, respectively																																																24,386,000
series a preferred stock – 0.01 par value, 4,000,000 shares authorized; 0 and 897,439 shares issued and outstanding (liquidation value of 0 and 2,468) at december 31, 2011 and 2010, respectively
series c preferred stock – 0.01 par value, 500,000 shares authorized; no shares issued or outstanding
common stock – 0.01 par value, 500,000,000 shares authorized; 297,503,033 and 255,412,706 shares issued and outstanding at december 31, 2011 and 2010, respectively																																																2,975,000
assets of discontinued operations																																																	2,929,000
current portion of lines of credit																																																	12,547,000	14,604,000	14,552,000
long-term liabilities																																																	2,154,000	1,600,000	1,883,000
series d preferred stock - 0.01 par value, 2,000,000 shares authorized; 1,209,677 shares issued and outstanding (liquidation value of 34,813 and 33,013) at september 30, 2011 and december 31, 2010, respectively																																																	26,128,000
series a preferred stock - 0.01 par value, 4,000,000 shares authorized; 0 and 897,439 shares issued and outstanding (liquidation value of 0 and 2,468) at september 30, 2011 and december 31, 2010, respectively
series c preferred stock - 0.01 par value, 500,000 shares authorized; no shares issued or outstanding
common stock - 0.01 par value, 500,000,000 shares authorized; 288,141,824 and 255,412,706 shares issued at september 30, 2011 and december 31, 2010, respectively																																																	2,881,000
series d preferred stock — 0.01 par value, 2,000,000 shares authorized; 1,209,677 shares issued and outstanding (liquidation value of 34,213 and 33,013) at june 30, 2011 and december 31, 2010, respectively																																																		26,128,000
series a preferred stock — 0.01 par value, 4,000,000 shares authorized; 0 and 897,439 shares issued and outstanding (liquidation value of 0 and 2,468) at june 30, 2011 and december 31, 2010, respectively
series c preferred stock — 0.01 par value, 500,000 shares authorized; no shares issued or outstanding
common stock — 0.01 par value, 500,000,000 shares authorized; 287,946,324 and 255,412,706 shares issued and outstanding at june 30, 2011 and december 31, 2010, respectively																																																		2,879,000
series d preferred stock — 0.01 par value, 2,000,000 shares authorized; 1,209,677 and 1,209,677 shares issued and outstanding (liquidation value of 33,613 and 33,013) at march 31, 2011 and december 31, 2010, respectively																																																			26,128,000
series a preferred stock — 0.01 par value, 4,000,000 shares authorized; 722,700 and 897,439 shares issued and outstanding (liquidation value of 2,076 and 2,468) at march 31, 2011 and december 31, 2010, respectively																																																			7,000
common stock — 0.01 par value, 500,000,000 shares authorized; 285,042,867 and 255,412,706 shares issued and outstanding at march 31, 2011 and december 31, 2010, respectively																																																			2,850,000
liabilities, series d preferred stock and shareholders’ equity
long-term liabilities — interest payable to related party
other long-term liabilities, principally deferred tax liabilities																																																				1,067,000
line of credit with related party, net of unamortized discount of 0 and 68, respectively
series d preferred stock — 0.01 par value, 2,000,000 shares authorized; 1,209,677 and 1,209,677 shares issued and outstanding (liquidation value of 33,013 and 30,613) at december 31, 2010 and 2009, respectively																																																				26,128,000
series a preferred stock — 0.01 par value, 4,000,000 shares authorized; 897,439 and 1,025,934 shares issued and outstanding (liquidation value of 2,468 and 2,564) at december 31, 2010 and 2009, respectively																																																				9,000
common stock — 0.01 par value, 500,000,000 shares authorized; 255,412,706 and 253,762,552 shares issued and outstanding at december 31, 2010 and 2009, respectively																																																				2,554,000
total liabilities, series d preferred stock and shareholders’ equity																																																				77,846,000

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