7Baggers

Ocular Therapeutix, Inc
(NASDAQ:OCUL) 

OCUL stock logo

Ocular Therapeutix, Inc., a biopharmaceutical company, focuses on the formulation, development, and commercialization of therapies for diseases and conditions of the eye using its bioresorbable hydrogel platform technology. The company markets ReSure Sealant, an ophthalmic device designed to prevent...

Founded: 2006
Full Time Employees: 161
CEO: Antony Mattessich  
Sector: Healthcare
Industry: Biotechnology
PharmaceuticalsOphthalmology
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Quarterly
Annual
    Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 2014-06-30 
                                                    
      revenue:
    		                                                
      product revenue
    		10,785,000 13,250,000 14,544,000 13,395,000 10,634,000 17,020,000 15,347,000 16,379,000 14,715,000 14,677,000 14,950,000 15,029,000 13,214,000 13,902,000 11,913,000 12,144,000 12,498,000 12,308,000 12,153,000 11,718,000 7,342,000 7,349,000 5,876,000 1,569,000 2,609,000 2,256,000 829,000 650,000 492,000 504,000 498,000 648,000 340,000 487,000 523,000 438,000 475,000 511,000 477,000 441,000 416,000 394,000 388,000 334,000 238,000    
      collaboration revenue
    		   64,000 64,000 62,000 78,000 62,000 59,000 124,000 131,000 157,000 160,000 173,000 52,000 122,000 689,000                        42,000 42,000 41,000 125,000 188,000    
      total revenue
    		10,785,000 13,250,000 14,544,000 13,459,000 10,698,000 17,082,000 15,425,000 16,441,000 14,774,000 14,801,000 15,081,000 15,186,000 13,374,000 14,075,000 11,965,000 12,266,000 13,187,000 12,308,000 12,153,000 11,718,000 7,342,000 7,349,000 5,876,000 1,569,000 2,609,000 2,256,000 829,000 650,000 492,000 504,000 498,000 648,000 340,000 487,000 523,000 438,000 475,000    458,000        
      yoy
    		0.81% -22.43% -5.71% -18.14% -27.59% 15.41% 2.28% 8.26% 10.47% 5.16% 26.04% 23.81% 1.42% 14.36% -1.55% 4.68% 79.61% 67.48% 106.82% 646.85% 181.41% 225.75% 608.81% 141.38% 430.28% 347.62% 66.47% 0.31% 44.71% 3.49% -4.78% 47.95% -28.42%    3.71%            
      qoq
    		-18.60% -8.90% 8.06% 25.81% -37.37% 10.74% -6.18% 11.28% -0.18% -1.86% -0.69% 13.55% -4.98% 17.63% -2.45% -6.98% 7.14% 1.28% 3.71% 59.60% -0.10% 25.07% 274.51% -39.86% 15.65% 172.14% 27.54% 32.11% -2.38% 1.20% -23.15% 90.59% -30.18% -6.88% 19.41% -7.79%             
      costs and operating expenses:
    		                                                
      cost of product revenue
    		1,329,000 1,594,000 1,774,000 1,944,000 1,262,000 1,230,000 1,561,000 1,509,000 1,326,000 1,386,000 1,377,000 1,304,000 1,214,000 1,012,000 1,073,000 1,155,000 1,300,000 1,108,000 1,310,000 1,096,000 892,000 680,000 450,000 134,000 819,000 839,000 806,000 552,000 128,000 117,000 115,000 153,000 80,000 113,000 125,000 104,000 115,000 127,000 112,000 105,000 99,000 92,000 91,000 80,000 56,000    
      research and development
    		66,213,000 50,800,000 52,358,000 51,081,000 42,857,000 40,989,000 37,054,000 28,857,000 20,735,000 16,195,000 15,019,000 15,094,000 14,747,000 13,543,000 13,719,000 13,100,000 13,100,000 12,578,000 12,719,000 13,859,000 10,927,000 7,624,000 6,951,000 8,021,000 6,098,000 10,125,000 10,235,000 9,414,000 11,317,000 10,258,000 9,685,000 8,745,000 8,227,000 7,908,000 8,126,000 8,117,000 6,729,000 7,328,000 5,686,000 6,978,000 7,073,000 6,886,000 8,263,000 6,743,000 4,719,000 5,148,000 4,482,000 4,292,000 
      selling and marketing
    		16,577,000 12,957,000 13,088,000 13,729,000 14,148,000 10,840,000 10,573,000 9,994,000 10,183,000 9,245,000 9,315,000 11,153,000 10,835,000 10,532,000 10,186,000 10,140,000 9,063,000 9,136,000 9,576,000 8,391,000 8,086,000 6,811,000 6,520,000 6,153,000 7,130,000 7,142,000 6,777,000 7,225,000 3,347,000 2,291,000 1,067,000 867,000 717,000 903,000 3,238,000 6,832,000 6,027,000 2,526,000 1,294,000 1,492,000 1,389,000 1,143,000 798,000 1,041,000 870,000 658,000 479,000 535,000 
      general and administrative
    		20,006,000 17,659,000 16,022,000 14,346,000 16,348,000 14,599,000 12,235,000 19,671,000 14,147,000 8,025,000 8,584,000 8,205,000 9,127,000 8,349,000 8,531,000 7,787,000 7,557,000 7,535,000 8,077,000 8,603,000 7,665,000 6,577,000 5,961,000 5,145,000 5,176,000 5,551,000 6,155,000 5,058,000 5,358,000 5,121,000 4,447,000 4,447,000 4,771,000 4,279,000 4,230,000 3,724,000 3,276,000 3,002,000 2,623,000 2,973,000 2,406,000 2,590,000 2,451,000 2,230,000 1,894,000 2,216,000 1,926,000 1,196,000 
      total costs and operating expenses
    		104,125,000 83,010,000 83,242,000 81,100,000 74,615,000 67,658,000 61,423,000 60,031,000 46,391,000 34,851,000 34,295,000 35,756,000 35,923,000 33,436,000 33,509,000 32,182,000 31,020,000 30,357,000 31,682,000 31,949,000 27,570,000 21,692,000 19,882,000 19,453,000 19,223,000 23,657,000 23,973,000 22,249,000 20,150,000 17,787,000 15,314,000 14,212,000 13,795,000 13,203,000 15,719,000 18,777,000 16,147,000 12,983,000 9,715,000 11,548,000 10,967,000        
      income from operations
    		-93,340,000 -69,760,000 -68,698,000 -67,641,000 -63,917,000 -50,576,000 -45,998,000 -43,590,000 -31,617,000 -20,050,000 -19,214,000 -20,570,000 -22,549,000 -19,361,000 -21,544,000 -19,916,000 -17,833,000 -18,049,000 -19,529,000 -20,231,000 -20,228,000 -14,343,000 -14,006,000 -17,884,000 -16,614,000 -21,401,000 -23,144,000 -21,599,000 -19,658,000 -17,283,000 -14,816,000 -13,564,000 -13,455,000 -12,716,000 -15,196,000 -18,339,000 -15,672,000 -12,472,000 -9,238,000 -11,107,000 -10,509,000 -10,275,000 -11,174,000 -9,635,000 -7,113,000 -7,547,000 -6,776,000 -5,946,000 
      yoy
    		46.03% 37.93% 49.35% 55.18% 102.16% 152.25% 139.40% 111.91% 40.21% 3.56% -10.82% 3.28% 26.45% 7.27% 10.32% -1.56% -11.84% 25.84% 39.43% 13.12% 21.75% -32.98% -39.48% -17.20% -15.48% 23.83% 56.21% 59.24% 46.10% 35.92% -2.50% -26.04% -14.15% 1.96% 64.49% 65.11% 49.13% 21.38% -17.33% 15.28% 47.74% 36.15% 64.91% 62.04%     
      qoq
    		33.80% 1.55% 1.56% 5.83% 26.38% 9.95% 5.52% 37.87% 57.69% 4.35% -6.59% -8.78% 16.47% -10.13% 8.17% 11.68% -1.20% -7.58% -3.47% 0.01% 41.03% 2.41% -21.68% 7.64% -22.37% -7.53% 7.15% 9.87% 13.74% 16.65% 9.23% 0.81% 5.81% -16.32% -17.14% 17.02% 25.66% 35.01% -16.83% 5.69% 2.28% -8.05% 15.97% 35.46% -5.75% 11.38% 13.96%  
      operating margin %
    		-865.46% -526.49% -472.35% -502.57% -597.47% -296.08% -298.20% -265.13% -214.00% -135.46% -127.41% -135.45% -168.60% -137.56% -180.06% -162.37% -135.23% -146.64% -160.69% -172.65% -275.51% -195.17% -238.36% -1139.83% -636.80% -948.63% -2791.80% -3322.92% -3995.53% -3429.17% -2975.10% -2093.21% -3957.35% -2611.09% -2905.54% -4186.99% -3299.37% -Infinity% -Infinity% -Infinity% -2294.54% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% -Infinity% 
      other income:
    		                                                
      interest income
    		6,050,000 7,343,000 3,729,000 3,455,000 3,826,000 4,671,000 5,653,000 6,036,000 3,922,000 1,459,000 1,212,000 748,000 563,000 423,000 285,000 73,000 18,000 6,000 7,000 8,000 12,000 6,000 6,000 17,000 139,000 213,000 308,000 379,000 329,000 258,000 230,000 215,000 176,000 104,000 115,000 113,000 92,000 68,000 69,000 80,000 87,000 45,000 53,000 28,000 40,000  5,000 1,000 
      interest expense
    		-2,777,000 -2,832,000 -3,002,000 -3,016,000 -2,984,000 -3,106,000 -3,224,000 -3,196,000 -4,051,000 -4,151,000 -3,426,000 -1,991,000 -1,768,000 -1,847,000 -1,797,000 -1,696,000 -1,683,000 -1,680,000 -1,658,000 -1,655,000 -1,679,000 -1,726,000 -1,715,000 -1,694,000 -1,633,000 -1,805,000 -1,651,000 -1,627,000 -1,018,000 -374,000 -424,000 -455,000 -486,000 -490,000 -491,000 -468,000 -443,000 -418,000 -426,000 -418,000 -418,000 -408,000 -406,000 -405,000 -505,000 -407,000 -412,000 -257,000 
      change in fair value of derivative liabilities
    		1,455,000 595,000 -1,447,000 -641,000 -978,000 623,000 7,076,000 -3,027,000 -5,152,000 -6,478,000 6,722,000                                      
      total other income
    		4,728,000 5,106,000 -720,000   2,188,000 9,505,000 -187,000 -33,231,000 -9,170,000 18,698,000 -112,000 -7,769,000 3,819,000 -2,644,000 1,150,000 5,291,000 14,199,000 22,186,000 11,750,000 23,349,000 -71,269,000 2,062,000 -18,684,000 -4,898,000 -4,616,000 4,366,000 -2,854,000 2,534,000                    
      net income
    		-88,612,000 -64,654,000 -69,418,000 -67,814,000 -64,053,000 -48,388,000 -36,493,000 -43,777,000 -64,848,000 -29,220,000 -516,000 -20,682,000 -30,318,000 -15,542,000 -24,188,000 -18,766,000    -8,481,000          -17,399,000 -15,010,000 -13,804,000 -13,765,000 -13,102,000 -15,567,000 -18,694,000 -16,023,000 -12,822,000 -9,596,000 -11,445,000 -10,840,000 -10,637,000 -11,524,000 -10,009,000     
      yoy
    		38.34% 33.62% 90.22% 54.91% -1.23% 65.60% 6972.29% 111.67% 113.89% 88.01% -97.87% 10.21%    121.27%              32.80% -3.58% -26.16% -14.09% 2.18% 62.22% 63.34% 47.81% 20.54% -16.73% 14.35%         
      qoq
    		37.06% -6.86% 2.37% 5.87% 32.37% 32.60% -16.64% -32.49% 121.93% 5562.79% -97.51% -31.78% 95.07% -35.74% 28.89%               15.92% 8.74% 0.28% 5.06% -15.83% -16.73% 16.67% 24.96% 33.62% -16.16% 5.58% 1.91% -7.70% 15.14%      
      net income margin %
    		-821.62% -487.95% -477.30% -503.86% -598.74% -283.27% -236.58% -266.27% -438.93% -197.42% -3.42% -136.19% -226.69% -110.42% -202.16% -152.99% 0% 0% 0% -72.38% 0% 0% 0% 0% 0% 0% 0% 0% 0% -3452.18% -3014.06% -2130.25% -4048.53% -2690.35% -2976.48% -4268.04% -3373.26% -Infinity% -Infinity% -Infinity% -2366.81% -Infinity% -Infinity% -Infinity% NaN% NaN% NaN% NaN% 
      net income per share
    		-0.4 -0.27 -0.38 -0.39 -0.38 -0.28 -0.22 -0.26 -0.49 -0.35 -0.01 -0.26 -0.39 -0.2 -0.31 -0.24 -0.16 -0.05 0.03 -0.11 0.04 -1.34 -0.19 -0.64 -0.41 -0.54 -0.4 -0.57 -0.41 -0.42 -0.38 -0.37 -0.4 -0.44 -0.54 -0.64 -0.58 -0.51 -0.39 -0.46 -0.44 -0.43 -0.47 -0.45 -0.35 0.24 -0.48 -2.1 
      weighted-average common shares outstanding, basic
    		224,099,410 187,241,483 183,919,808 172,594,662 169,396,989 158,265,162 166,992,735 165,824,778 132,021,945 79,827,362 79,373,272 78,047,705 77,386,287 76,875,035 76,975,839 76,764,296 76,745,663 76,392,870 76,552,060 76,324,367 76,071,017  62,992,558  51,900,882  46,944,536  42,251,292                    
      weighted-average common shares outstanding, diluted
    		224,099,410 187,241,483 183,919,808 172,594,662 169,396,989 158,265,162 166,992,735 165,824,778 132,021,945 85,596,594 85,142,504 78,047,705 77,386,287 82,644,267 76,975,839 82,533,528 82,514,895 82,162,102 85,446,886 82,093,599 87,245,706  68,761,790  51,900,882  52,713,768  44,174,369                    
      loss on extinguishment of debt
    		        -27,950,000                                        
      gain on sale of property and equipment
    		 7,250  29,000                                             
      total other expense
    		   -173,000 -136,000                         -116,000 -194,000 -240,000 -310,000 -386,000 -371,000 -355,000 -351,000 -350,000 -358,000 -338,000 -331,000 -362,000 -350,000 -374,000 -465,000 -407,000 -518,000 -446,000 
      gains and losses on extinguishment of debt
    		          14,190,000                                      
      other expense
    		            -1,000                                    
      other income
    		              1,000  -2,000   1,000               5,000   -250 -1,000   1,000 3,000 3,000   -111,000 -190,000 
      change in fair value of derivative liability
    		           1,131,000 -6,563,000 5,243,000 -1,133,000 2,773,000 6,958,000 15,872,000 23,837,000 13,396,000 25,016,000 -69,549,000 3,771,000 -17,007,000 -3,404,000 -3,024,000 5,717,000 -1,606,000 3,223,000                    
      net (loss) per share, diluted
    		             -0.183 -0.31                                  
      net income attributable to common stockholders
    		                -12,542,000    3,121,000                            
      net income and comprehensive income
    		                 -675,750 2,657,000                              
      net loss and comprehensive loss
    		                     -85,612,000 -11,944,000 -36,568,000 -21,512,000 -26,017,000 -18,778,000 -24,453,000 -17,124,000                -7,578,000 -7,954,000 -7,294,000 -6,392,000 
      weighted-average common shares outstanding, basic and diluted
    		                     60,752,225  57,368,292  45,273,231  42,910,084  38,115,142 39,017,922 37,524,512 34,792,848 28,818,196 29,087,654 29,026,259 27,643,746 24,816,348 24,853,880 24,770,059 24,751,682 23,244,162 24,713,597 22,167,274 21,362,731 10,652,865 15,165,612 3,044,605 
      comprehensive loss:
    		                                                
      other comprehensive loss:
    		                                                
      unrealized gain on marketable securities
    		                                   9  -10 -5 10         
      total other comprehensive income
    		                                   9  -10 -5 10 68        
      total comprehensive loss
    		                             -17,399 -15,010 -13,804 -13,765 -13,102 -15,567 -18,685 -16,027 -12,832 -9,601 -11,435 -10,772 -10,689 -11,532 -10,017     
      unrealized loss on marketable securities
    		                                         -52 -8 -8     
      total other comprehensive loss
    		                                         -52 -8 -8     
      other comprehensive income:
    		                                                
      total revenue:
    		                                     344,000 477,000 441,000  328,500 429,000 459,000 426,000    
      unrealized gains on marketable securities
    		                                        68        
      operating expenses:
    		                                                
      total operating expenses
    		                                         10,711,000 11,603,000 10,094,000 7,539,000 8,052,000 6,919,000 6,043,000 
      accretion of redeemable convertible preferred stock to redemption value
    		                                               -5,000 
      net loss attributable to common stockholders
    		                                         -10,637,000 -11,524,000 -10,009,000 -7,578,000 -7,954,000 -7,294,000 -6,397,000 
      revenue
    		                                             66,750 143,000 97,000 
      cost of revenue
    		                                             15,250 32,000 20,000 
    Balance Sheets:
    Quarterly
    Annual
      Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 2014-06-30 
                                                      
        assets
      		                                                
        current assets:
      		                                                
        cash and cash equivalents
      		666,699,000 737,060,000 344,772,000 391,134,000 349,681,000 392,102,000 427,220,000 459,690,000 482,888,000 195,807,000 110,550,000 66,606,000 79,026,000 102,300,000 120,950,000 134,539,000 145,417,000 164,164,000 179,281,000 191,860,000 209,378,000 228,057,000 70,642,000 84,294,000 48,152,000 54,437,000 65,414,000 61,765,000 76,251,000 54,062,000 56,861,000 56,834,000 62,911,000 41,538,000 51,165,000 63,049,000 54,682,000 32,936,000 52,234,000 48,170,000 46,212,000 30,784,000 41,198,000 78,686,000 12,523,000 37,393,000 80,892,000 19,944,000 
        accounts receivable
      		24,347,000 30,650,000 30,768,000 30,412,000 25,221,000 32,388,000 30,235,000 30,232,000 26,546,000 26,179,000 23,589,000 27,309,000 21,124,000 21,325,000 19,802,000 20,482,000 23,207,000 21,135,000 19,552,000 18,734,000 13,631,000 12,252,000 7,779,000 2,874,000 3,429,000 2,548,000 1,114,000 615,000 276,000 201,000 240,000 285,000 170,000 226,000 278,000 211,000 244,000 250,000 243,000 223,000 227,000 193,000 189,000 164,000 352,000 329,000 53,000 60,000 
        inventory
      		3,737,000 3,564,000 3,488,000 3,039,000 3,269,000 3,040,000 2,405,000 2,547,000 2,574,000 2,305,000 2,257,000 2,204,000 2,266,000 1,974,000 1,545,000 1,500,000 1,358,000 1,250,000 1,222,000 1,112,000 1,123,000 1,201,000 1,154,000 1,067,000 1,107,000 954,000 895,000 762,000 265,000 217,000 102,000 131,000 139,000 122,000 127,000 90,000 96,000 113,000 126,000 149,000 127,000 134,000 147,000 145,000 158,000 133,000 117,000 109,000 
        prepaid expenses and other current assets
      		11,212,000 10,855,000 7,952,000 8,790,000 9,523,000 13,457,000 13,151,000 6,116,000 7,666,000 7,794,000 4,862,000 4,593,000 4,746,000 4,028,000 3,318,000 3,801,000 4,670,000 4,751,000 3,877,000 4,817,000 4,000,000 4,650,000 2,328,000 2,058,000 2,465,000 2,231,000 2,213,000 2,294,000 2,380,000 1,713,000 1,071,000 1,222,000 1,256,000 1,453,000 883,000 1,978,000 2,557,000 1,390,000 708,000 715,000 1,287,000 1,592,000 1,919,000 2,608,000 1,537,000 893,000 1,211,000 283,000 
        total current assets
      		705,995,000 782,129,000 386,980,000 433,375,000 387,694,000 440,987,000 473,011,000 498,585,000 519,824,000 232,235,000 141,258,000 100,712,000 107,162,000 129,627,000 145,615,000 160,322,000 174,652,000 191,300,000 203,932,000 216,523,000 228,132,000 246,160,000 81,903,000 90,293,000 55,153,000 60,170,000 69,636,000 65,436,000 79,172,000 56,193,000 58,274,000 58,472,000 64,476,000 43,339,000 52,453,000 68,328,000 83,276,000 69,898,000 76,824,000 84,974,000 97,097,000 106,983,000 115,898,000 126,639,000 69,470,000 76,183,000 82,274,000 22,594,000 
        property and equipment
      		18,425,000 19,676,000 16,954,000 10,461,000 10,784,000 9,389,000 10,050,000 10,887,000 11,450,000 11,739,000 12,494,000 12,830,000 12,022,000 9,856,000 7,196,000 6,680,000 6,614,000 6,956,000 6,914,000 7,042,000 7,527,000 8,095,000 8,490,000 8,934,000 9,473,000 10,151,000 10,474,000 10,532,000 10,548,000 10,236,000 10,382,000 10,373,000 10,595,000 10,478,000 10,218,000 9,619,000 5,693,000 3,313,000 3,795,000 3,199,000 3,107,000 3,095,000 3,193,000 2,603,000 1,799,000 1,782,000 1,376,000 1,152,000 
        restricted cash
      		1,614,000 1,614,000 1,614,000 1,614,000 1,614,000    150,000 150,000 1,764,000 1,764,000 1,764,000 1,764,000 1,764,000 1,764,000 1,764,000 1,764,000 1,764,000 1,764,000 1,764,000 1,764,000 1,764,000 1,764,000 1,764,000 1,764,000 1,764,000 6,764,000 6,614,000 6,614,000 1,614,000 1,614,000 1,614,000 1,614,000 1,728,000 1,728,000 1,728,000 1,728,000 1,728,000 1,728,000 228,000 228,000 228,000 228,000 228,000 228,000 228,000 228,000 
        operating lease assets
      		6,495,000 4,638,000 5,334,000 5,883,000 5,828,000 5,945,000 5,694,000 6,005,000 6,059,000 6,472,000 6,868,000 7,252,000 7,625,000 8,042,000 4,004,000 4,305,000 4,592,000 4,867,000 5,129,000 5,378,000 5,617,000 5,844,000 6,062,000 6,269,000 6,467,000 6,655,000 6,836,000 7,010,000 5,156,000                    
        total assets
      		732,529,000 808,057,000 410,882,000 451,333,000 405,920,000 457,935,000 490,369,000 517,091,000 538,947,000 252,060,000 162,384,000 122,558,000 128,573,000 149,289,000 158,579,000 173,071,000 187,622,000 204,887,000 217,739,000 230,707,000 243,040,000 261,863,000 98,219,000 107,260,000 72,857,000 78,740,000 88,710,000 89,742,000 101,490,000 73,043,000 70,270,000 70,459,000 76,685,000 55,431,000 64,399,000 79,675,000 90,697,000 74,939,000 82,347,000 89,901,000 100,432,000 110,306,000 119,319,000 129,470,000 71,497,000 78,193,000 83,878,000 23,974,000 
        liabilities and stockholders’ equity
      		                                                
        current liabilities:
      		                                                
        accounts payable
      		8,026,000 4,154,000 6,260,000 5,889,000 4,626,000 4,176,000 4,001,000 3,689,000 6,453,000 4,389,000 3,984,000 3,572,000 5,441,000 5,123,000 5,308,000 3,703,000 3,420,000 4,592,000 4,246,000 3,881,000 4,152,000 2,709,000 3,238,000 2,650,000 2,839,000 3,268,000 3,461,000 4,044,000 3,902,000 2,965,000 2,777,000 2,137,000 3,477,000 3,571,000 2,599,000 6,307,000 3,754,000 2,116,000 1,680,000 1,611,000 2,063,000 1,957,000 1,624,000 2,812,000 2,195,000 1,316,000 649,000 1,525,000 
        accrued expenses and other current liabilities
      		36,487,000 43,835,000 40,272,000 34,417,000 31,080,000 35,117,000 30,451,000 24,358,000 16,040,000 28,666,000 28,887,000 24,598,000 21,993,000 24,097,000 21,614,000 19,450,000 17,636,000 20,121,000 19,358,000 16,182,000 13,574,000 14,307,000 12,165,000 5,769,000 5,018,000 7,635,000 6,471,000 5,059,000 4,037,000                    
        operating lease liabilities
      		3,170,000 2,817,000 2,762,000 2,625,000 2,156,000 1,933,000 1,717,000 1,656,000 1,542,000 1,586,000 1,878,000 1,713,000 1,818,000 1,599,000 1,744,000 1,771,000 1,696,000 1,624,000 1,554,000 1,487,000 1,421,000 1,358,000 1,297,000 1,238,000 1,181,000 1,126,000 1,073,000 1,024,000 675,000                    
        total current liabilities
      		47,683,000 50,806,000 49,294,000 42,931,000 37,926,000 41,354,000 36,359,000 29,972,000 24,298,000 34,896,000 35,066,000 32,357,000 29,715,000 31,395,000 29,269,000 26,113,000 23,960,000 26,337,000 25,158,000 21,550,000 27,437,000 26,664,000 22,906,000 13,803,000 11,112,000 12,029,000 11,005,000 10,127,000 8,614,000 9,159,000 13,406,000 11,899,000 13,151,000 13,426,000 10,945,000 13,130,000 8,656,000 8,300,000 8,243,000 6,419,000 6,003,000 5,378,000 11,181,000 9,591,000 7,227,000 5,874,000 3,379,000 4,489,000 
        other liabilities:
      		                                                
        operating lease liabilities, net of current portion
      		4,230,000 2,815,000 3,629,000 4,408,000 4,866,000 5,345,000 5,592,000 6,100,000 6,407,000 6,878,000 7,251,000 7,689,000 8,114,000 8,678,000 4,610,000 4,999,000 5,472,000 5,924,000 6,355,000 6,770,000 7,169,000 7,548,000 7,909,000 8,256,000 8,590,000 8,905,000 9,206,000 9,493,000 7,909,000                    
        derivative liability
      		12,071,000 13,903,000 14,962,000 14,024,000 13,852,000       11,783,000 12,914,000 6,351,000 11,594,000 10,461,000 13,234,000 20,192,000 36,064,000 59,901,000 73,297,000 98,313,000 28,764,000 32,535,000 15,528,000 12,124,000 9,100,000 13,068,000 11,462,000                    
        deferred revenue
      		14,000,000    64,000 128,000 190,000 269,000 263,000 255,000 317,000 391,000 463,000 576,000 603,000 1,189,000 1,208,000 13,000,000 12,000,000 12,000,000 12,000,000 12,000,000                    42,000 83,000 125,000 250,000 188,000 250,000 250,000 
        notes payable
      		72,062,000 71,336,000 70,617,000 69,906,000 69,202,000 68,505,000 67,815,000 67,132,000 66,456,000 65,787,000 65,124,000                                      
        other non-current liabilities
      		909,000 887,000 151,000 148,000 144,000 141,000 117,000 114,000 111,000 108,000 106,000 104,000 100,000 93,000                                   
        total liabilities
      		150,955,000 153,747,000 152,653,000 145,417,000 139,990,000 142,591,000 138,348,000 139,396,000 130,964,000 160,929,000 154,531,000 119,471,000 118,862,000 113,910,000 112,350,000 107,268,000 107,827,000 116,888,000 130,399,000 150,460,000 159,632,000 185,768,000 102,345,000 101,916,000 83,516,000 82,370,000 77,409,000 81,484,000 75,842,000 37,168,000 24,753,000 24,730,000 27,501,000 29,284,000 28,477,000 31,650,000 26,792,000 22,931,000 20,053,000 19,453,000 20,262,000 20,718,000 20,511,000 20,358,000 19,424,000 19,497,000 18,276,000 19,054,000 
        commitments and contingencies
      		                                                
        stockholders’ equity:
      		                                                
        preferred stock, 0.0001 par value...
      		                                                
        common stock, 0.0001 par value...
      		22,000 22,000 18,000 17,000 16,000 16,000 16,000 16,000 15,000 12,000 8,000 8,000 8,000 8,000 8,000 8,000 8,000 8,000 8,000 8,000 8,000 8,000 6,000 6,000 5,000 5,000 5,000 4,000 4,000 4,000 4,000 4,000 4,000 3,000 3,000 3,000 3,000 3,000 2,000 2,000 2,000 2,000 2,000 2,000 2,000 2,000 2,000  
        additional paid-in capital
      		1,827,187,000 1,811,311,000 1,350,580,000 1,328,850,000 1,221,051,000 1,206,412,000 1,194,701,000 1,183,882,000 1,170,394,000 788,697,000 676,203,000 670,921,000 656,863,000 652,213,000 647,521,000 642,907,000 638,133,000 633,795,000 629,286,000 624,850,000 619,530,000 615,338,000 449,507,000 447,033,000 394,463,000 379,980,000 368,894,000 347,074,000 340,011,000 333,114,000 325,357,000 310,559,000 300,210,000 263,409,000 260,082,000 256,618,000 253,813,000 225,889,000 223,344,000 221,897,000 220,184,000 218,830,000 217,361,000 216,133,000 149,077,000 148,122,000 147,074,000 4,745,000 
        accumulated deficit
      		-1,245,635,000 -1,157,023,000 -1,092,369,000 -1,022,951,000 -955,137,000 -891,084,000 -842,696,000 -806,203,000 -762,426,000 -697,578,000 -668,358,000 -667,842,000 -647,160,000 -616,842,000 -601,300,000 -577,112,000 -558,346,000 -545,804,000 -541,954,000 -544,611,000 -536,130,000 -539,251,000 -453,639,000 -441,695,000 -405,127,000 -383,615,000 -357,598,000 -338,820,000 -314,367,000 -297,243,000 -279,844,000 -264,834,000 -251,030,000 -237,265,000 -224,163,000 -208,596,000 -189,902,000 -173,879,000 -161,057,000 -151,461,000 -140,016,000 -129,176,000 -118,539,000 -107,015,000 -97,006,000 -89,428,000 -81,474,000 -74,180,000 
        total stockholders’ equity
      		581,574,000 654,310,000 258,229,000 305,916,000 265,930,000 315,344,000 352,021,000 377,695,000 407,983,000 91,131,000 7,853,000 3,087,000 9,711,000 35,379,000 46,229,000 65,803,000 79,795,000 87,999,000 87,340,000 80,247,000 83,408,000 76,095,000  5,344,000  -3,630,000 11,301,000 8,258,000 25,648,000 35,875,000 45,517,000 45,729,000 49,184,000 26,147,000 35,922,000 48,025,000 63,905,000 52,008,000 62,294,000 70,448,000 80,170,000 89,588,000 98,808,000 109,112,000 52,073,000 58,696,000 65,602,000  
        total liabilities and stockholders’ equity
      		732,529,000 808,057,000 410,882,000 451,333,000 405,920,000 457,935,000 490,369,000 517,091,000 538,947,000 252,060,000 162,384,000 122,558,000 128,573,000 149,289,000 158,579,000 173,071,000 187,622,000 204,887,000 217,739,000 230,707,000 243,040,000 261,863,000 98,219,000 107,260,000  78,740,000 88,710,000 89,742,000 101,490,000 73,043,000 70,270,000 70,459,000 76,685,000 55,431,000 64,399,000 79,675,000 90,697,000 74,939,000 82,347,000 89,901,000 100,432,000 110,306,000 119,319,000 129,470,000 71,497,000    
        deferred revenue, net of current portion
      		 14,000,000 14,000,000 14,000,000 14,000,000 14,000,000 14,000,000 14,000,000 14,068,000 14,135,000 14,197,000 14,254,000 13,340,000 13,387,000 13,533,000 13,000,000 13,103,000                                
        derivative liabilities
      		     13,246,000 14,465,000 22,078,000 19,624,000 29,987,000 24,022,000                                      
        convertible notes
      		         9,138,000 8,765,000 29,981,000                                     
        notes payable, net of discount, current
      		           2,083,000         8,290,000 8,290,000 6,206,000 4,146,000 2,074,000      6,094,000 6,082,000 6,071,000 5,545,000 3,993,000 2,444,000 897,000 1,549,000 3,772,000 2,466,000 1,161,000  5,883,000 4,370,000 2,860,000 1,354,000  1,085,000 
        notes payable, net of discount, net of current portion
      		           23,303,000                                     
        notes payable, net of discount
      		            25,321,000 25,257,000 25,192,000 25,128,000 25,063,000 25,000,000 24,936,000 24,891,000 14,907,000 16,936,000 18,964,000 20,970,000 22,987,000 25,007,000 24,952,000 24,898,000 24,843,000                    
        2026 convertible notes
      		            29,358,000 28,749,000 28,152,000 27,567,000 26,995,000 26,435,000 25,886,000 25,348,000 24,822,000 24,307,000 23,802,000 26,352,000 25,299,000 24,305,000 23,146,000 23,898,000 23,014,000                    
        stockholders’ equity
      		                                                
        total stockholders’ deficit
      		                      -4,126,000  -10,659,000                       -69,435,000 
        liabilities and stockholders’ deficit
      		                                                
        total liabilities and stockholders’ deficit
      		                        72,857,000                        
        other liabilities
      		                                                
        accrued expenses and deferred rent
      		                             6,194,000 4,535,000 3,680,000 3,603,000 4,310,000 4,353,000 4,379,000 4,005,000 4,635,000 2,791,000 2,342,000 2,779,000 3,379,000       
        deferred rent, long-term
      		                             3,221,000 3,274,000 3,283,000 3,336,000 3,387,000 3,608,000 3,146,000 1,315,000 537,000 32,000 42,000 55,000 68,000 81,000 94,000 103,000 112,000 121,000 119,000 
        notes payable, net of discount, long-term
      		                             24,788,000 8,073,000 9,548,000 11,014,000 12,471,000 13,924,000 15,374,000 16,821,000 14,094,000 11,778,000 12,992,000 14,204,000 15,272,000 9,249,000 10,673,000 12,094,000 13,511,000 14,776,000 13,594,000 
        marketable securities
      		                                   3,000,000 25,697,000 35,209,000 23,513,000 35,717,000 49,244,000 74,280,000 72,445,000 45,036,000 54,900,000 37,435,000   
        accumulated other comprehensive loss
      		                                         -68,000 -16,000 -8,000     
        accumulated other comprehensive income
      		                                      5,000 10,000         
        accrued expenses
      		                                          3,591,000 2,284,000 1,922,000 3,016,000 2,480,000 1,629,000 
        accounts receivable from related party
      		                                              1,000 1,000 
        liabilities, redeemable convertible preferred stock and stockholders’ equity
      		                                                
        preferred stock warrants
      		                                               852,000 
        redeemable convertible preferred stock (series a, b, c, d and d-1), 0.001 par value...
      		                                               74,355,000 
        total liabilities, redeemable convertible preferred stock and stockholders’ equity
      		                                             78,193,000 83,878,000  
        deferred offering costs
      		                                               2,197,000 
        liabilities, redeemable convertible preferred stock and stockholders’ deficit
      		                                                
        stockholders’ deficit:
      		                                                
        total liabilities, redeemable convertible preferred stock and stockholders’ deficit
      		                                               23,974,000 
      Cashflow Statements:
      Quarterly
      Annual
        Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 
                                                       
          cash flows from operating activities:
        		                                               
          net loss
        		-88,612,000 -64,654,000 -69,418,000 -67,814,000 -64,053,000 -48,388,000 -36,493,000 -43,777,000 -64,848,000 -29,220,000 -516,000 -20,682,000 -30,318,000 -15,542,000 -24,188,000   -3,850,000 2,657,000   -85,612,000 -11,944,000 -36,568,000 -21,512,000 -26,017,000 -18,778,000 -24,453,000 -17,124,000 -17,399,000 -15,010,000 -13,804,000 -13,765,000 -13,102,000 -15,567,000 -18,694,000 -16,023,000 -12,822,000 -9,596,000 -11,445,000 -10,840,000 -10,637,000 -11,524,000 -10,009,000 -7,578,000 -7,954,000 -7,294,000 
          adjustments to reconcile net loss to net cash from operating activities
        		                                               
          stock-based compensation expense
        		15,582,000 11,359,000 11,691,000 9,678,000 10,456,000 7,197,000 6,641,000 11,293,000 7,978,000 4,328,000 4,512,000 4,413,000 4,572,000 4,234,000 4,240,000 4,281,000 4,209,000 3,841,000 3,758,000 4,292,000 3,086,000 2,104,000 1,936,000 1,826,000 1,665,000 1,953,000 3,169,000 1,695,000 1,942,000 1,949,000 1,873,000 1,830,000 1,831,000 2,109,000 1,750,000 1,757,000 1,705,000 1,723,000 1,369,000 1,515,000 1,349,000 1,336,000 1,231,000 1,152,000 921,000 977,000 607,000 
          non-cash interest expense
        		1,381,000 495,000 758,000 708,000 1,436,000 576,000 621,000 569,000 1,968,000 1,553,000 2,072,000 1,253,000 1,228,000 1,237,000 1,225,000 1,205,000 1,186,000 1,188,000 1,158,000 1,150,000 1,132,000 1,136,000 1,123,000 1,108,000 1,048,000 1,214,000 1,051,000 1,009,000 409,000 132,000 80,000 87,000 98,000 99,000 99,000 100,000 110,000 265,000 35,000 36,000 35,000 54,000 38,000 37,000 37,000 37,000 41,000 
          change in fair value of derivative liabilities
        		-1,455,000 -595,000 1,447,000 641,000 978,000 -623,000 -7,076,000 3,027,000 5,152,000 6,478,000                                      
          depreciation and amortization expense
        		1,283,000 1,247,000 1,069,000 1,026,000 981,000 951,000 959,000 956,000 920,000 958,000 890,000 652,000 483,000 491,000 509,000 552,000 557,000 570,000 594,000 611,000 646,000 667,000 665,000 707,000 734,000 674,000 669,000 598,000 589,000 582,000 573,000 566,000 565,000 528,000 482,000 354,000 261,000 253,000 216,000 207,000 205,000 200,000 194,000 187,000 173,000   
          loss on disposal of items of property and equipment
        		4,866,000                                               
          changes in operating assets and liabilities:
        		                                               
          accounts receivable
        		6,303,000 118,000 -356,000 -5,191,000 7,167,000 -2,153,000 -3,000 -3,686,000 -367,000 -2,590,000 3,720,000 -6,185,000 201,000 -1,523,000 680,000 2,725,000 -2,072,000 -1,583,000 -818,000 -5,103,000 -1,379,000 -4,473,000 -4,905,000 555,000 -881,000 -1,434,000 -499,000 -339,000 -75,000 39,000 45,000 -115,000 56,000 52,000 -67,000 33,000 6,000 -7,000 -20,000 4,000 -34,000 -4,000 -25,000 188,000 -23,000 -276,000 7,000 
          prepaid expenses and other current assets
        		-357,000 -2,903,000 522,000 1,049,000 3,934,000 -306,000 -7,035,000 1,550,000 128,000 -2,932,000 -269,000 153,000 -718,000 -710,000 483,000 869,000 81,000 -874,000 940,000 -817,000 650,000 -2,322,000 -270,000 407,000 -234,000 -18,000 81,000 86,000 -667,000 -642,000 151,000 34,000 197,000 -462,000 1,095,000 579,000 -1,167,000 40,000 7,000 572,000 305,000 267,000 429,000 -919,000 170,000 318,000 -305,000 
          inventory
        		-173,000 -76,000 -449,000 230,000 -229,000 -635,000 142,000 27,000 -269,000 -48,000 -53,000 62,000 -292,000 -429,000 -45,000 -142,000 -108,000 -28,000 -110,000 11,000 78,000 -47,000 -87,000 40,000 -153,000 -59,000 -133,000 -497,000 -48,000 -115,000   -17,000  -37,000 6,000 17,000 13,000 23,000 -22,000 7,000 13,000 -2,000 13,000 -25,000 -16,000 -8,000 
          accounts payable
        		3,719,000 -1,353,000 -1,272,000 1,731,000 7,000 112,000 297,000 -2,420,000 1,693,000 656,000 247,000 -1,345,000 1,025,000 -1,122,000 1,310,000 304,000 -1,113,000 366,000 175,000 -268,000 1,523,000 -565,000 899,000 -550,000 -236,000 92,000 -742,000 13,000 761,000 207,000 536,000 -877,000 -662,000 769,000 -2,759,000 2,263,000 659,000 130,000 173,000 -541,000 79,000 708,000 -1,011,000 498,000 153,000 444,000 -282,000 
          operating lease assets
        		-1,857,000 696,000 549,000 -55,000 117,000 -273,000 311,000 54,000 413,000     -4,038,000 301,000 287,000 275,000 262,000 249,000 239,000 227,000 218,000 207,000   181,000                      
          accrued expenses
        		-8,441,000 2,176,000 5,376,000 2,841,000 -5,145,000 4,206,000 5,603,000 7,860,000 -14,031,000 -1,246,000 2,597,000 2,050,000 -2,628,000 1,937,000 1,653,000 1,102,000 -3,048,000 188,000 2,601,000 2,039,000 -1,111,000 1,400,000 2,777,000 751,000 -2,617,000                       
          deferred revenue
        		 0 0 -64,000 -64,000 -62,000 -79,000 -62,000 -59,000 -124,000 -131,000 842,000 -160,000 -173,000 -53,000 -122,000 1,311,000                     0 0 0 -42,000 -41,000 -42,000 -125,000 62,000   
          operating lease liabilities
        		1,768,000 -759,000 -642,000 11,000 -256,000 -31,000 -447,000 -193,000 -515,000     3,923,000 -416,000 -398,000 -380,000 -361,000 -348,000 -333,000 -316,000 -300,000 -288,000 -277,000 -260,000 -248,000 -286,000 -64,000 -246,000                   
          net cash from operating activities
        		-65,993,000 -54,249,000 -50,725,000 -55,238,000 -44,671,000 -39,429,000 -36,559,000 -24,802,000 -33,887,000 -22,454,000 -7,732,000 -20,075,000 -19,973,000 -16,958,000 -13,169,000 -10,876,000 -18,600,000 -15,153,000 -12,982,000 -20,056,000 -17,359,000 -6,246,000 -13,658,000 -14,796,000 -18,854,000 -19,467,000 -19,544,000 -19,181,000 -19,386,000 -13,648,000 -10,873,000 -12,233,000 -12,473,000 -10,383,000 -14,382,000 -11,131,000 -14,577,000 -7,612,000 -7,331,000 -9,802,000 -9,256,000 -8,636,000 -9,700,000 -8,528,000 -6,879,000 -5,626,000 -6,333,000 
          capital expenditures
        		-3,335,000 -3,404,000 -4,377,000 -1,686,000 -1,369,000 -157,000 -56,000 -1,091,000 137,000 -710,000 -108,000 -2,520,000 -2,733,000 -1,243,000 -562,000 -373,000 -153,000 -649,000 -85,000 -131,000 -148,000 -233,000 -206,000 -83,000 -228,000 -851,000 -220,000 -404,000 -549,000 -522,000 -364,000 -768,000 -80,000 -340,000 -2,991,000 -3,716,000 -667,000 -680,000 -923,000 -243,000 -18,000 -848,000 458,000 -746,000 -349,000 -441,000 -321,000 
          free cash flows
        		-69,328,000 -57,653,000 -55,102,000 -56,924,000 -46,040,000 -39,586,000 -36,615,000 -25,893,000 -33,750,000 -23,164,000 -7,840,000 -22,595,000 -22,706,000 -18,201,000 -13,731,000 -11,249,000 -18,753,000 -15,802,000 -13,067,000 -20,187,000 -17,507,000 -6,479,000 -13,864,000 -14,879,000 -19,082,000 -20,318,000 -19,764,000 -19,585,000 -19,935,000 -14,170,000 -11,237,000 -13,001,000 -12,553,000 -10,723,000 -17,373,000 -14,847,000 -15,244,000 -8,292,000 -8,254,000 -10,045,000 -9,274,000 -9,484,000 -9,242,000 -9,274,000 -7,228,000 -6,067,000 -6,654,000 
          cash flows from investing activities:
        		                                               
          purchases of property and equipment
        		-4,662,000 -2,839,000 -5,993,000 -1,245,000 -1,933,000 -202,000 -89,000 -742,000 -255,000 -459,000 -259,000 -1,990,000 -3,379,000 -2,150,000 -794,000 -495,000 -276,000 -631,000 -276,000 -129,000 -158,000 -253,000 -214,000 -125,000 -249,000 -601,000 -419,000 -493,000 -725,000 -479,000 -473,000 -556,000 -381,000 -564,000 -2,036,000 -3,998,000 -1,654,000 -680,000 -869,000 -243,000 -127,000 -473,000 -76,000 -875,000 -354,000 -441,000 -274,000 
          net cash from investing activities
        		-4,662,000 -2,839,000 -5,993,000 -1,115,000 -1,933,000 -202,000 -89,000 -742,000 -255,000 -459,000 -259,000 -1,990,000 -3,379,000 -2,150,000 -794,000 -495,000 -276,000 -631,000 -276,000 -129,000 -158,000 -253,000 -214,000 -125,000 -249,000 -601,000 -419,000 -493,000 -725,000 -479,000 -473,000 -556,000 -381,000 -450,000 969,000 18,702,000 7,846,000 -12,379,000 11,317,000 11,757,000 24,873,000 -2,086,000 -27,587,000 8,958,000 -17,854,000 -37,767,000 -274,000 
          cash flows from financing activities:
        		                                               
          proceeds from exercise of stock options
        		294,000 2,937,000 10,356,000 3,068,000 4,183,000 3,989,000 4,178,000 1,704,000 4,870,000 8,000 62,000 403,000 78,000 0 374,000 11,000 129,000 172,000 679,000 538,000 1,197,000 1,541,000 538,000 378,000 128,000 44,000 33,000 0 1,000 51,000 73,000 7,000 266,000 506,000 141,000 36,000 2,000           
          net cash from financing activities
        		294,000 449,376,000 10,356,000 97,806,000 4,183,000 4,513,000 4,178,000 2,196,000 321,223,000 108,170,000 51,935,000 9,645,000 78,000 458,000 374,000 493,000 129,000 667,000 679,000 2,667,000 -1,162,000 163,913,000 220,000 51,063,000 12,818,000 9,091,000 18,612,000 5,338,000 42,300,000 16,328,000 11,373,000 6,712,000 34,227,000 1,206,000 1,529,000 796,000 28,477,000 693,000 78,000 3,000 -189,000 308,000 -201,000 65,733,000 -137,000 -106,000 67,555,000 
          net increase in cash, cash equivalents and restricted cash
        		-70,361,000 392,288,000 -46,362,000 41,453,000 -42,421,000 -35,118,000 -32,470,000 -23,348,000 287,081,000 85,257,000        -15,117,000 -12,579,000   157,415,000 -13,652,000 36,142,000 -6,285,000 -10,977,000 -1,351,000 -14,336,000 22,189,000 2,201,000 27,000 -6,077,000 21,373,000               
          cash, cash equivalents and restricted cash at beginning of period
        		738,674,000 0 0 0 393,716,000 0 0 0 197,571,000 0 0 0 104,064,000 0 0 0 165,928,000 0 0 0 229,821,000 0 0 0 56,201,000 0 0 0 60,676,000 0 0 0 43,152,000               
          cash, cash equivalents and restricted cash at end of period
        		668,313,000 392,288,000 -46,362,000 41,453,000 351,295,000 -35,118,000 -32,470,000 -23,348,000 484,652,000 85,257,000 43,944,000 -12,420,000 80,790,000 -18,650,000 -13,589,000 -10,878,000 147,181,000 -15,117,000 -12,579,000 -17,518,000 211,142,000 157,415,000 -13,652,000 36,142,000 49,916,000 -10,977,000 -1,351,000 -14,336,000 82,865,000 2,201,000 27,000 -6,077,000 64,525,000               
          supplemental disclosure of cash flow information:
        		                                               
          cash paid for interest
        		2,189,000 2,244,000 2,337,000 2,308,000 2,140,000 3,335,000 2,603,000 2,628,000 12,967,000 2,599,000 1,344,000 820,000 701,000 626,000 531,000 495,000 495,000 489,000   593,000    585,000         386,000 387,000       309,000 317,000 315,000 310,000   
          supplemental disclosure of non-cash investing and financing activities:
        		                                               
          change in right-of-use asset as a result of new, modified, and terminated leases
        		2,512,000                                               
          additions to property and equipment included in accounts payable and accrued expenses
        		1,327,000 -565,000 1,616,000 -441,000 564,000 45,000 33,000 -349,000 392,000 -251,000 151,000 -530,000 646,000 907,000 232,000 122,000 123,000                      -54,000        -47,000 
          gains and losses on disposal of items of property and equipment
        		                                               
          gains and losses on extinguishment of debt
        		     0    0                                      
          proceeds from sales of property and equipment
        		 0 0                                             
          proceeds from issuance of short-term bridge loan
        		         0 0 0 2,000,000                                   
          proceeds from issuance of barings notes payable
        		         0                                      
          proceeds from issuance of common stock pursuant to employee stock purchase plan
        		 879,000 0   524,000 0   433,000 0   458,000 0   495,000 0   397,000 0   157,000 0   178,000 0   119,000 0   150,000    101,000 0     
          payments of debt refinancing costs
        		                                               
          proceeds from issuance of common stock upon public offering, net of issuance costs
        		 445,560,000 0       107,729,000 708,000        0 0 -275,000                           
          repayment of midcap notes payable
        		         0                                      
          repayment from issuance of short-term bridge loan
        		                                               
          proceeds from issuance of common stock and pre-funded warrants upon private placement, net of issuance costs
        		     0 0 0 316,353,000                                       
          gain on disposal of items of property and equipment
        		  0                                             
          loss on extinguishment of debt
        		       0 27,950,000                                     0 0 
          receivable from exercise of stock options included in prepaid expenses and other current assets
        		                                               
          gain on disposal of property and equipment
        		         2,000 0 0 -1,000     0                              
          proceeds from issuance of notes payable
        		                 0 0               0 0 0 3,700,000           
          payments of debt financing costs
        		                                               
          issuance costs from the issuance of common stock upon public offering in prior period
        		                                               
          repayment of notes payable
        		                 0 0 -2,084,000 -2,083,000         -1,543,000 -1,543,000 -1,542,000 -1,029,000 0 0 0 -1,300,000           
          repayment of short-term bridge loan
        		         0 0 0 -2,000,000                                   
          operating lease assets and liabilities
        		          111,000 -157,000 72,000                                   
          change in fair value of derivative liability
        		           -1,131,000 6,563,000 -5,243,000 1,133,000 -2,773,000 -6,958,000 -15,872,000 -23,837,000 -13,396,000 -25,016,000 69,549,000 33,647,000 -20,411,000 3,404,000 3,024,000 -5,717,000 1,606,000 -3,223,000                   
          net decrease in cash, cash equivalents and restricted cash
        		           -12,420,000 -23,274,000 -18,650,000 -13,589,000 -10,878,000 -18,747,000    -18,679,000                           
          proceeds from the paycheck protection program loan
        		                     0 0                         
          repayment of the paycheck protection program loan
        		                     0 0                         
          issuance costs from the issuance of common stock upon public offering
        		                                               
          public offering costs included in accounts payable and accrued expenses at balance sheet dates
        		                             31,000 -9,000 -265,000 285,000 96,000   55,000           
          loss on disposal of property and equipment
        		              -1,000 0 2,000         0            1,268,000    0 0   0 0 
          net income
        		                -12,542,000    3,121,000                           
          proceeds from issuance of 2026 convertible notes, net of issuance costs
        		                         0 0 -70,000 37,345,000                   
          additional right of use asset and related lease liability
        		                         0 0                     
          additions to property and equipment included in accounts payable and accrued expenses at balance sheet dates
        		                 -18,000 191,000 -2,000 10,000 20,000 8,000 42,000 21,000 -250,000 199,000 89,000 176,000 -43,000 109,000 -212,000 301,000        109,000       
          cashless exercise of warrant
        		                                               
          derivative liability in connection with issuance of 2026 convertible notes
        		                         0 1,749,000 0 14,685,000                   
          adjustments to reconcile net income to net cash from operating activities
        		                                               
          proceeds from issuance of common stock upon public offering
        		                     161,975,000 -318,000 50,335,000 12,690,000                       
          revenue:
        		                                               
          product revenue
        		                                               
          total revenue
        		                                               
          costs and operating expenses:
        		                                               
          cost of product revenue
        		                                               
          research and development
        		                                               
          selling and marketing
        		                                               
          general and administrative
        		                                               
          total costs and operating expenses
        		                                               
          loss from operations
        		                                               
          other income:
        		                                               
          interest income
        		                                               
          interest expense
        		                                               
          total other income
        		                                               
          net loss and comprehensive loss
        		                                               
          net loss per share
        		                                               
          weighted-average common shares outstanding, basic and diluted
        		                                               
          ​
        		                                               
          amortization of operating lease asset
        		                            187,000                   
          right of use asset
        		                        188,000                       
          purchase of premium on marketable securities
        		                                     -20,000    -313,000 -50,000 8,000 17,000   
          amortization of premium on marketable securities
        		                                 0 0 6,000 11,000 13,000 20,000 49,000 104,000 96,000 148,000 21,000 18,000   
          accrued expenses and deferred rent
        		                         1,171,000 1,412,000 1,022,000 -1,891,000 1,599,000 850,000 38,000 -776,000 -381,000 627,000 2,465,000 -153,000 1,532,000 446,000 -165,000 -424,000 -315,000 914,000 424,000 -804,000 850,000 654,000 
          proceeds from sale of property and equipment
        		                                 0    0    0 0     
          purchases of marketable securities
        		                                 0 0 0 -3,000,000           
          proceeds from maturities of marketable securities
        		                                               
          proceeds from issuance of common stock offering
        		                         8,890,000 18,579,000 5,114,000 4,954,000 5,610,000 12,843,000 8,128,000 34,990,000 581,000 1,585,000 800,000 26,272,000           
          payments of insurance costs financed by a third party
        		                                 0 -197,000 -197,000 -197,000           
          non-cash operating lease costs
        		                                               
          insurance premium financed by a third party
        		                                         0      
          change in restricted cash
        		                                     0 0         
          net increase in cash and cash equivalents
        		                                 -9,627,000 -11,884,000 8,367,000 21,746,000 -19,298,000 4,064,000 1,958,000 15,428,000 -10,414,000 -37,488,000   -43,499,000 60,948,000 
          cash and cash equivalents at beginning of period
        		                                 0 0 0 32,936,000 0 0 0 30,784,000 0 0 0 37,393,000 0 0 
          cash and cash equivalents at end of period
        		                                 -9,627,000 -11,884,000 8,367,000 54,682,000 -19,298,000 4,064,000 1,958,000 46,212,000 -10,414,000 -37,488,000 66,163,000 12,523,000 -43,499,000 60,948,000 
          additions to property and equipment included in accounts payable at balance sheet dates
        		                                 224,000 -955,000 282,000 987,000     -375,000 534,000 129,000 5,000   
          maturities of marketable securities
        		                                               
          maturities of investments
        		                                   22,700,000 12,500,000  14,684,000 25,000,000 25,000,000  30,000,000     
          licensing and consultant fees paid in common stock
        		                                             0 0 
          revaluation of preferred stock warrants
        		                                             0 108,000 
          accounts receivable from related party
        		                                             1,000 0 
          proceeds from issuance of notes payable and preferred stock warrants
        		                                               
          proceeds from issuance of public offering
        		                                         564,000 -34,000     
          payments of offering costs
        		                                               
          payments of insurance costs financed by a third-party
        		                                     -130,000 0 -195,000 -194,000 -222,000 -198,000 -171,000 -171,000 -171,000  
          accretion of redeemable convertible preferred stock to redemption value
        		                                               
          conversion of redeemable convertible preferred stock to common stock
        		                                             0  
          conversion of warrants for redeemable convertible preferred stock to warrants for common stock
        		                                             0  
          initial public offering costs included in accounts payable
        		                                               
          purchases of investments
        		                                      -2,500,000    -57,511,000 0 -17,500,000   
          proceeds from exercise of common stock options
        		                                      78,000 70,000 5,000  31,000 110,000 34,000  4,000 
          proceeds from issuance of public offerings
        		                                               
          purchase of (premium) discount on marketable securities
        		                                               
          proceeds from issuance common stock pursuant to employee stock purchase plan
        		                                               
          deferred offering costs included in accounts payable and accrued expenses
        		                                              -989,000 
          purchase discount on marketable securities
        		                                               
          proceeds from issuance of redeemable convertible preferred stock, net of issuance costs
        		                                               
          cashless exercise of warrants
        		                                               
          proceeds from issuance of notes payable and preferred stock warrants, net of issuance costs
        		                                              0 
          repayments of notes payable
        		                                              0 
          payments of initial public offering costs
        		                                             -6,000 -1,905,000 
          fair value of preferred stock warrants at grant date
        		                                              0 
          net decrease in cash and cash equivalents
        		                                            -24,870,000   
          other assets
        		                                               
          proceeds from sales or maturities of investments
        		                                               
          proceeds from issuance of common stock
        		                                             0  
          depreciation expense
        		                                              139,000 
          accretion of redeemable convertible preferred stock to redemption values
        		                                              0 
          prepaid expense included in accrued expense