7Baggers
Quarterly
Annual
    Unit: USD2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 2014-06-30 2014-03-31 2013-12-31 
      
    		                                                
      cash flows from operating activities
    		                                                
      net income
    		16,822,000 -36,251,000 -41,036,000 -15,421,000 56,309,000 -55,664,000 -52,190,000 -46,072,000 17,554,000 57,469,000 -38,009,000 12,802,000 -24,813,000 -41,304,000 -66,443,000 -58,022,000 -52,886,000 -39,935,000 -51,272,000 -2,087,000 -36,043,000 -46,885,000 -44,724,000 -30,396,000 -44,631,000 -31,767,000 -45,017,000 -44,644,000 -34,029,000 -43,244,000 -49,536,000 105,727,000 -47,043,000 -40,655,000 -37,655,000 -34,783,000 -33,846,000 40,464,000 -30,363,000 -28,451,000 -15,442,000 -21,376,000 45,129,000 -19,018,000 -3,928,000 -12,258,665 -3,108,335 -3,204,984 
      adjustments to reconcile net income loss to net cash from operating activities:
    		                                                
      depreciation and amortization expense
    		1,789,000 1,907,000 1,771,000  1,835,000 1,811,000 1,841,000  1,950,000 2,812,000 2,983,000  2,844,000 2,877,000 2,913,000  2,796,000 2,781,000 2,729,000    2,809,000  2,636,000 2,580,000 2,903,000  2,728,000 1,202,000 1,338,000 1,342,000 1,905,000 2,003,000 1,978,000 1,974,000 2,077,000 1,786,000 1,771,000          
      amortization of premiums and discounts on marketable securities
    		-511,000 -311,000 -182,000 -185,000 -371,000 -939,000 -1,315,000 -1,728,000 -1,872,000 -1,032,000 -372,000 -337,000 112,000 294,000 334,000 340,000 459,000 441,000 367,000 127,000 14,000                            
      stock-based compensation
    		3,549,000 3,690,000 4,386,000  5,970,000 6,651,000 5,553,000  4,790,000 4,391,000 4,833,000  5,123,000 5,300,000 5,274,000  6,358,000 6,070,000 5,286,000  5,832,000 5,096,000 4,491,000  5,398,000 4,884,000 3,799,000  4,573,000 4,163,000 3,432,000                  
      non-cash royalty revenue
    		          -90,000                                      
      non-cash interest expense
    		3,329,000       0 0 774,000 656,000                                      
      non-cash lease expense
    		405,000 400,000 399,000 -2,498,000 607,000 611,000 617,000 786,000 869,000 893,000 941,000                                      
      other adjustments
    		                                                
      changes in operating assets and liabilities:
    		                                                
      accounts receivable
    		-56,698,000 -1,990,000 -6,233,000 4,442,000 -2,560,000 1,028,000 3,148,000 14,944,000 -18,901,000 29,750,000 20,062,000 -42,384,000 4,547,000 -3,479,000 -4,520,000 3,374,000 31,488,000 -38,100,000 15,934,000 -4,304,000 428,000 -7,399,000 938,000 -3,241,000 -3,891,000 503,000 23,468,000 -8,613,000 -3,134,000 -10,555,000 6,361,000 -11,448,000 -203,000 102,000 671,000 244,000 75,367,000 -75,864,000 -1,287,000 1,520,000 1,590,000 -2,615,000 1,216,000 2,380,000 -2,670,000 -899,279 258,279 277,263 
      inventory
    		525,000 151,000 -9,426,000 -165,000 -2,129,000 133,000 -27,000 -155,000 377,000 -34,000 42,000 -364,000 57,000 572,000 -210,000 -842,000 894,000 -304,000 -6,172,000                              
      prepaid expenses and other current assets
    		-1,062,000 1,327,000 3,535,000 -1,675,000 -565,000 598,000 75,000 -1,436,000 -2,035,000 3,243,000 443,000 -889,000 3,287,000 2,154,000 6,457,000 -3,108,000 -106,000 265,000 -1,239,000  -2,439,000                            
      other non current assets
    		5,000 93,000 66,000 -370,000 0 -1,000 201,000 0 0   -13,172,000 846,000 821,000 801,000                                  
      accounts payable
    		1,309,000 -1,640,000 1,252,000 -1,700,000 1,413,000 -5,422,000 4,179,000 2,888,000 -503,000 44,000 -1,148,000 37,000 1,999,000 -976,000 -11,920,000 9,056,000 -3,599,000 -161,000 1,829,000 3,586,000 1,613,000 810,000 -2,286,000 1,700,000 1,685,000         197,000 -2,223,000 2,365,000 222,000 33,000 -388,000 -1,035,000 688,000 409,000 -225,000 -2,719,000 411,000 -1,156,016 1,964,016 1,370,806 
      accrued expenses and other current liabilities
    		1,738,000 -6,488,000 -1,163,000 4,355,000 198,000 6,341,000 -5,891,000 -1,435,000 -2,095,000 -616,000 -677,000 -4,454,000 1,513,000 -1,154,000 -543,000 -8,351,000 2,379,000 4,510,000 855,000                              
      lease liabilities
    		-238,000 -219,000 5,000 3,362,000 42,000 45,000 41,000 -138,000 -210,000 -229,000 -284,000 12,811,000 -1,183,000 -1,145,000 -1,119,000 -1,079,000 -1,028,000 -990,000 -683,000 789,000 -579,000 -665,000 -869,000 -966,000 3,616,000 -855,000 1,086,000                      
      deferred revenue
    		2,525,000 -7,941,000 -264,000 -7,330,000 -511,000 302,000 -1,875,000 -1,950,000 14,635,000 954,000 -2,213,000 57,298,000 -5,559,000 -14,198,000 11,280,000 -5,243,000 -4,152,000 19,260,000 -601,000 -3,656,000 -1,049,000 -1,519,000 -2,248,000 -13,755,000 3,747,000 -5,431,000 -5,430,000 19,212,000 -2,436,000 -1,936,000 -1,435,000 9,199,000 -800,000 -801,000 -1,065,000 729,000 -1,741,000 -1,286,000 -1,893,000 -555,000 -3,856,000 -3,863,000 -3,949,000 -3,949,000 -9,927,000 7,769,523 9,423,477 -2,707,650 
      other non current liabilities
    		-340,000               0   258,000                              
      net cash from operating activities
    		-30,186,000 -46,985,000 -46,890,000 -38,407,000 60,162,000 -44,485,000 -45,643,000 -28,037,000 -35,246,000 -2,089,000 -12,833,000 29,320,000 -9,422,000 -49,161,000 -57,696,000 -54,309,000 -14,795,000 -45,690,000 -29,036,000 -5,533,000 -25,677,000 -36,546,000 -44,142,000 -38,044,000 -17,388,000 -48,838,000 -30,000,000 -27,228,000 -36,980,000 -57,731,000 -31,295,000 111,845,000 -31,354,000 -30,755,000 -35,331,000 -28,329,000 49,786,000 -33,226,000 -31,910,000 -24,155,000 -7,634,000 -25,465,000 43,593,000 -20,164,000 -14,331,000 -4,150,230 5,886,230 -1,183,683 
      capex
    		-426,000 -715,000 -529,000 -620,000 -592,000 -1,035,000 -1,459,000 -620,000 -499,000 -286,000 -359,000 -393,000 -804,000 -1,011,000 -1,415,000 -1,375,000 -2,133,000 -2,067,000 -626,000 0 -499,000 -594,000 -1,253,000 0 -780,000 -587,000 -1,675,000 0 -4,216,000 -5,504,000 -14,519,000 0 -9,850,000 -7,303,000 -1,492,000 -1,062,000 -1,980,000 -5,508,000 -2,831,000 -2,780,000 -2,608,000 -2,812,000 -997,000 -1,658,000 -672,000 -794,725 -447,275 -924,076 
      free cash flows
    		-30,612,000 -47,700,000 -47,419,000 -39,027,000 59,570,000 -45,520,000 -47,102,000 -28,657,000 -35,745,000 -2,375,000 -13,192,000 28,927,000 -10,226,000 -50,172,000 -59,111,000 -55,684,000 -16,928,000 -47,757,000 -29,662,000 -5,533,000 -26,176,000 -37,140,000 -45,395,000 -38,044,000 -18,168,000 -49,425,000 -31,675,000 -27,228,000 -41,196,000 -63,235,000 -45,814,000 111,845,000 -41,204,000 -38,058,000 -36,823,000 -29,391,000 47,806,000 -38,734,000 -34,741,000 -26,935,000 -10,242,000 -28,277,000 42,596,000 -21,822,000 -15,003,000 -4,944,955 5,438,955 -2,107,759 
      cash flows from investing activities
    		                                                
      purchases of marketable securities
    		-66,062,000 -45,513,000 -7,915,000 -13,788,000 -4,889,000 -8,008,000 -50,497,000 -22,467,000 -69,176,000 -130,744,000 -17,296,000 -45,145,000 0 -21,380,000 -54,077,000 -66,428,000 -47,234,000 -23,665,000 -93,881,000 -72,515,000 -79,031,000 -11,013,000 -61,186,000 -50,221,000 -71,873,000 -60,708,000 -81,597,000 -12,711,000 -33,548,000 -62,039,000 -24,452,000 -45,998,000 -32,187,000 0 -56,937,000 -78,065,000 -67,305,000 -119,276,000 -83,116,000          
      proceeds from sale and maturities of marketable securities
    		46,117,000 8,590,000 18,346,000  41,000,000 56,400,000 76,750,000  36,140,000 17,500,000 45,750,000  72,750,000 45,430,000 37,010,000  46,750,000 39,550,000 60,250,000  36,249,000 52,614,000 73,003,000  66,281,000 51,175,000 12,780,000  37,758,000 59,732,000 58,358,000  46,501,000 80,433,000 50,072,000  66,122,000 68,198,000 73,413,000          
      purchases of property, equipment and software
    		-426,000 -715,000 -529,000 -620,000 -592,000 -1,035,000 -1,459,000 -620,000 -499,000 -286,000 -359,000 -393,000 -804,000 -1,011,000 -1,415,000 -1,375,000 -2,133,000 -2,067,000 -626,000                              
      proceeds from sales of equipment
    		   0 80,000   0 10,000                                        
      net cash from investing activities
    		-20,371,000 -37,638,000 9,902,000 41,467,000 35,599,000 47,437,000 24,794,000 38,822,000 -33,525,000 -113,476,000 28,095,000 -5,788,000 71,946,000 23,039,000 -18,482,000 -13,553,000 -2,617,000 13,818,000 -34,257,000 -16,075,000 -43,281,000 41,007,000 10,564,000 7,626,000 -6,372,000 -10,120,000 -70,492,000 45,074,000 -6,000 -7,811,000 19,387,000 8,639,000 4,464,000 73,130,000 -8,357,000 2,034,000 -3,163,000 -56,586,000 -12,534,000 -145,690,000 -2,608,000 -2,812,000 -997,000 -1,658,000 -672,000 -794,725 -447,275 -924,076 
      cash flows from financing activities
    		                                                
      proceeds from stock option exercises and espp purchases
    		0   159,000 6,000 631,000 2,639,000 274,000 52,000 222,000 5,000 260,000 14,000   -763,000 812,000 2,452,000 2,458,000 1,141,000 2,092,000 2,503,000 162,000 297,000 37,000   735,000 132,000 496,000 629,000 449,000 28,000                
      taxes paid related to net share settlement of equity awards
    		0 0 -282,000 -4,000 -74,000 -6,000 -2,391,000 0 -141,000 -7,000 -158,000      -1,457,000                                
      net proceeds from sale of future royalties
    		0       0 50,000,000 0 99,655,000                                      
      net cash from financing activities
    		0 69,739,000 -282,000 155,000 -68,000 625,000 248,000 273,000 49,911,000 59,000 100,118,000 1,359,000 0 263,000 37,000 800,000 18,973,000 2,346,000 100,658,000 1,102,000 74,063,000 99,015,000 162,000 297,000 37,000 633,000 119,005,000 475,000 132,000 103,755,000 629,000 359,000 1,147,000 33,734,000 108,000 492,000 1,011,000 127,000 224,000 250,000 140,982,000 170,000 62,947,000 222,000 180,000 237,548 76,801,452 85,019,970 
      net change in cash and cash equivalents
    		-50,557,000 -14,884,000 -37,270,000 3,215,000 95,693,000 3,577,000 -20,601,000 11,058,000 -18,860,000 -115,506,000 115,380,000 24,891,000 62,524,000 -25,859,000 -76,141,000 -67,062,000 1,561,000 -29,526,000 37,365,000 -20,506,000 5,105,000 103,476,000 -33,416,000 -30,121,000 -23,723,000 -58,325,000 18,513,000 18,321,000 -36,854,000 38,213,000 -11,279,000 120,843,000 -25,743,000 76,109,000 -43,580,000 -25,803,000 47,634,000 -89,685,000 -44,220,000 -169,595,000 130,740,000 -28,107,000 105,543,000 -21,600,000 -14,823,000 -4,707,407 82,240,407 82,912,211 
      cash and cash equivalents at beginning of period
    		0 0 182,840,000 0 0 0 100,956,000 0 0 0 108,884,000 0 0 0 123,469,000 0 0 0 181,131,000 0 0 0 126,472,000 0 0 0 220,128,000 0 0 0 211,727,000 0 0 0 84,098,000 0 0 0 196,172,000 0 0 0 157,591,000 0 0 -409 116,481,409 0 
      cash and cash equivalents at end of period
    		-50,557,000 -14,884,000 145,570,000 3,215,000 95,693,000 3,577,000 80,355,000 11,058,000 -18,860,000 -115,506,000 224,264,000 24,891,000 62,524,000 -25,859,000 47,328,000 -67,062,000 1,561,000 -29,526,000 218,496,000 -20,506,000 5,105,000 103,476,000 93,056,000 -30,121,000 -23,723,000 -58,325,000 238,641,000 18,321,000 -36,854,000 38,213,000 200,448,000 120,843,000 -25,743,000 76,109,000 40,518,000 -25,803,000 47,634,000 -89,685,000 151,952,000 -169,595,000 130,740,000 -28,107,000 263,134,000 -21,600,000 -14,823,000 -4,707,816 198,721,816 82,912,211 
      supplemental cash flow disclosures
    		                                                
      cash paid for income taxes
    		0                                                
      non-cash operating and investing activities
    		                                                
      property and equipment included in accounts payable or accruals
    		-26,000                                                
      other non-cash items
    		   0 -19,000   0 187,000   0 1,805,000   433,000                                 
      supplemental cash flow information
    		                                                
      property, equipment and software included in accounts payable or accruals
    		  353,000   -206,000 242,000  -11,000 0 177,000  0 144,000 151,000  -49,000 -368,000 486,000                              
      operating activities
    		                                                
      adjustments to reconcile net income to net cash from operating activities:
    		                                                
      depreciation and amortization
    		                                                
      share-based compensation
    		                                 3,602,000 3,461,000 3,039,000 3,002,000 3,123,000 3,001,000 2,216,000 2,098,000 1,902,000 1,631,000 995,000 856,000 781,396 611,604 468,601 
      gain on royalty monetization arrangement
    		       0 -50,000,000                                        
      gain on sale of margenza
    		                                                
      (gain) loss on disposal of assets
    		   0                                             
      proceeds from sales and maturities of marketable securities
    		                                                
      proceeds from sale of margenza
    		                                                
      proceeds from issuance of common stock, net of offering costs
    		       0 0 0 616,000     0 19,618,000 0 98,200,000 -38,000 73,982,000   0 0 0 118,657,000 0 0   -50,000 1,119,000       0 140,775,000 0 62,692,000 -17,000 -306,000 237,548 76,801,452  
      principal payments on royalty monetization arrangement
    		       -1,000 0                                        
      loss on disposal of assets
    		       0 8,000                                        
      proceeds from stock option exercises
    		              37,000            348,000        108,000 531,000 1,011,000 127,000 224,000 279,000 207,000 170,000 255,000 258,000     
      right-of-use assets modified in exchange for operating lease obligation
    		                                                
      other assets
    		                742,000 731,000 3,673,000 -1,034,000 620,000 300,000 695,000 1,043,000 18,470,000 -19,012,000 -2,079,000 4,713,000 -3,782,000 -5,551,000 40,000 94,000 103,000 146,000 -81,000 875,000 -173,000 -128,000 -298,000     -1,331,000 381,000 1,165,347 -1,394,347  
      prepaid expenses
    		                      -1,345,000 734,000 -2,403,000 -1,307,000 -1,902,000 -2,091,000 -1,142,000 155,000 -177,000 110,000 747,000 1,010,000 -1,535,000 -2,172,000 2,471,000 -2,079,000 103,000 178,000 1,082,000 551,000 594,000 -1,758,000 -353,000 -163,200 -964,800 131,744 
      deferred rent
    		                           -233,000 -222,000 -204,000 -312,000 -367,000 7,137,000 -329,000 -326,000 -288,000 -283,000 -283,000 -280,000 48,000 5,052,000 -426,000 -24,000 -38,000 -45,000 -45,310 -105,690 15,539 
      purchase of treasury stock
    		                                                
      non-cash operating and investing activities:
    		                                                
      fair value of warrants received
    		                                                
      depreciation expense
    		                    2,962,000                   1,192,000 489,000 636,000 546,000 505,000 482,000 436,783 398,217 358,725 
      accrued expenses
    		                    2,162,000 5,455,000 -2,118,000 -1,379,000 -2,015,000 1,634,000 -4,297,000 -5,954,000 1,245,000 6,738,000 1,477,000 3,331,000 3,316,000 4,362,000 1,823,000 764,000 3,029,000 2,654,000 -1,788,000 2,355,000 815,000 1,304,000 -929,000 3,899,000 721,000 574,399 -848,399 2,643,741 
      other liabilities
    		                    802,000 928,000 515,000                          
      purchases of property and equipment
    		                    -499,000 -594,000 -1,253,000  -780,000 -587,000 -1,675,000  -4,216,000 -5,504,000 -14,519,000  -9,850,000 -7,303,000 -1,492,000 -1,062,000 -1,980,000 -5,508,000 -2,831,000 -2,780,000 -2,608,000 -2,812,000 -997,000 -1,658,000 -672,000 -794,725 -447,275 -924,076 
      right-of-use assets modified in exchange for operating lease obligations
    		                        4,420,000 0 1,988,000                      
      lease exit liability
    		                            0 0 -298,000 -417,000 -405,000 -392,000 -379,000 -349,000 -339,000 -1,646,000 -488,000 -460,000 -450,000 -1,987,000 -396,000 -372,000 -364,000 -355,208 -347,792 -162,468 
      accounts payable and other liabilities
    		                          -2,531,000  -781,000 -8,499,000 7,815,000                  
      fair value of warrants received, including change in value
    		                                                
      restricted cash
    		                                       0    0     
      fair value adjustment of warrant liability
    		                                               0 
      noncash financing activities:
    		                                                
      conversion of preferred stock
    		                                                
      fair value adjustment of warrant liabilities
    		                                                
      proceeds from issuance of preferred stock
    		                                                
      proceeds from issuance of common stock
    		                                                
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