7Baggers

Immunocore Holdings plc
(NASDAQ:IMCR) 

IMCR stock logo

Immunocore Holdings plc, a late-stage biotechnology company, develops immunotherapies for the treatment of oncology, infectious, and autoimmune diseases. The company's lead oncology therapeutic candidate is tebentafusp, which is in a randomized Phase 3 clinical trial in patients with previously untr...

Founded: 2008
Sector: Healthcare
Industry: Biotechnology

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At a glance:
Bull Thesis:
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Moat:
Income Statements:
Quarterly
Annual
    Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-11-07 2023-06-30 2023-05-10 2023-03-01 2022-12-31 2022-11-09 2022-08-09 2022-05-11 2021-12-31 2021-11-10 2021-08-11 2021-03-31 2020-12-31 
                           
      revenue:
                           
      revenue from sale of therapies
    106,677,000 104,478,000 103,693,000 97,964,000 93,881,000                   
      total revenue
    106,677,000 104,478,000 103,693,000 97,964,000 93,881,000 84,052,000 80,248,000 75,400,000 70,502,000 249,365,112 62,888 60,704 44,541 173,591 37,212 45,871 32,002 22,474 6,593 5,924 5,733 8,270  
      yoy
    13.63% 24.30% 29.22% 29.93% 33.16% -66.29% 127504.63% 124109.28% 158185.62% 143550.95% 69.00% 32.34% 39.18% 672.41% 464.42% 674.32% 458.21% 171.75%      
      qoq
    2.10% 0.76% 5.85% 4.35% 11.69% 4.74% 6.43% 6.95% -71.73% 396422.57% 3.60% 36.29% -74.34% 366.49% -18.88% 43.34% 42.40% 240.88% 11.29% 3.33% -30.68%   
      cost and operating expenses:
                           
      cost of revenue from sale of therapies
    -434,000 -2,703,000 -513,000 -1,040,000 -831,000                   
      research and development expense
    -61,113,000 -78,821,000 -70,572,000 -69,008,000 -56,468,000 -40,325,250 -52,770,000 -51,072,000 -57,459,000               
      selling, general and administrative expense
    -37,850,000 -42,645,000 -39,779,000 -42,791,000 -40,198,000 -28,364,250 -35,532,000 -38,638,000 -39,287,000               
      income from operations
    7,280,000 -19,691,000 -7,171,000 -14,875,000 -3,616,000 -19,452,000 -8,502,000 -16,017,000 -26,490,000               
      yoy
    -301.33% 1.23% -15.66% -7.13% -86.35%                   
      qoq
    -136.97% 174.59% -51.79% 311.37% -81.41% 128.79% -46.92% -39.54%                
      operating margin %
    6.82% -18.85% -6.92% -15.18% -3.85% -23.14% -10.59% -21.24% -37.57% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0%  
      other income:
                           
      interest income
    3,418,000 3,906,000 4,123,000 4,271,000 4,176,000 5,173,000 5,960,000 6,239,000 8,246,000               
      interest expense
    -3,051,000 -3,053,000 -3,043,000 -3,045,000 -3,025,000 -7,038,000 -4,290,000 -4,277,000 -3,239,000               
      foreign currency gains
    3,849,000                       
      other income
    1,776,000 4,504,000 5,062,000 4,693,000 5,469,000 993,000 8,962,000 4,433,000                
      net income before income taxes
    13,272,000 -826,500 304,000  6,084,000 -7,029,000 6,093,000                 
      income tax expense
    -301,000   -606,000 -1,061,000   -1,486,000 -357,000               
      net income
    12,971,000 -30,060,000 -177,000 -10,300,000 5,023,000 -23,771,000 8,736,000 -11,616,000 -24,436,000               
      yoy
    158.23% 26.46% -102.03% -11.33% -120.56%                   
      qoq
    -143.15% 16883.05% -98.28% -305.06% -121.13% -372.10% -175.21% -52.46%                
      net income margin %
    12.16% -28.77% -0.17% -10.51% 5.35% -28.28% 10.89% -15.41% -34.66% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0%  
      other comprehensive income:
                           
      exchange differences on translation of foreign operations
    -7,289,000 1,922,000 -3,392,000 6,476,000 673,000 -2,590,000 3,247,000 944,000 897,000    380    -323 205 18 -38 -38 -92  
      total comprehensive income
    5,682,000 -424,250 -3,569,000 -3,824,000 5,696,000 -5,557,000 11,983,000                 
      basic net income per share
    0.26 -0.028   0.1 -0.138 0.17                 
      basic weighted-average number of shares outstanding
    50,754,763  50,403,717  50,086,684  50,021,939                 
      diluted net income per share
    0.25 -0.028   0.1 -0.138 0.17                 
      diluted weighted-average number of shares outstanding
    52,934,787  50,403,717  51,949,798  52,808,434                 
      collaboration revenue
           53,000 160,000 10,690,839 2,161 2,860 2,489 32,521 3,367 5,451 4,302 11,963      
      foreign currency gain
     -1,460,000 1,333,000 -738,000 3,080,000 -4,497,000 3,963,000                 
      income tax benefit
     -14,266,000 -481,000   1,050,000 2,643,000                 
      net loss before income taxes
       -9,694,000    -10,130,000 -24,079,000               
      basic and diluted net loss per share
       -0.2    -0.23 -0.49               
      basic and diluted weighted-average number of shares outstanding
     50,345,666  50,294,205  49,991,064  50,014,086 49,877,218 48,888,975              
      product revenue
         56,484,250 80,248,000 75,347,000 70,342,000 238,674,273 60,727 57,844 42,052 130,610 35,859 37,023 23,992 7,682      
      cost of product revenue
         -600,250 -448,000 -1,707,000 -246,000 -1,036,731 -269 -1,126 -178 -548 -70 -70 -34 -248      
      foreign currency loss
           -508,000 -2,406,000               
      total comprehensive loss
           -10,672,000 -23,539,000               
      other expense
            -190,000               
      pre-product, revenue
                   3,397        
      research and development expenses
             -9,673.25 -38,693 -36,560   -17,266.5 -25,943        
      selling and administrative expenses
             -6,195 -24,780 -43,064 -33,301 -113,189 -37,407 -12,986 -18,811 -20,106      
      operating profit
             -213.5 -854             
      finance income
             1,249.25 4,997 4,336 2,546 3,809 2,347 665 118 10 12 22  
      finance costs
             -498.25 -1,993 -1,989 -1,620 -9,290 -2,665 -1,987 -1,397 -1,333 -1,348 -1,317 -1,288 -1,860  
      net finance income /
             751 3,004 2,347 926           
      profit before taxes
             537.5 2,150             
      income tax credit
             5,602,824 176   3,528 -2,702 1,385 2,151 1,655 -214 2,125 2,813 4,681  
      profit for the period
             581.5 2,326             
      basic profit per share - / £
             0.013 0.05             
      diluted profit per share - / £
             0.01 0.04             
      basic weighted-average number of shares
              49,134,037             
      diluted weighted-average number of shares
              54,158,967             
      operating income
             -10,338.75 -41,355 -20,046 -17,387 -47,833 -20,367 6,872 -6,993 -16,460 -37,832 -30,950 -34,499 -31,881  
      loss before taxes
             -8,741 -34,964   -53,314 -5,865 5,550        
      income tax (charge) / credit
             -74.25 -297 -192 -236           
      loss for the period
             -8,815.25 -35,261 -17,891 -16,697 -49,786 -4,459.25 6,935 -6,121 -16,128 -23,033.5 -30,134 -32,962 -29,038  
      basic and diluted loss per share - / £
             -0.18 -0.72 -0.37            
      weighted-average number of shares
              48,671,732             
      pre-product revenue
                 10,460 -2,014  3,708 2,829      
      total revenue from sale of therapies
               57,844  141,070 33,845 40,420 27,700       
      loss before taxation
               -17,699            
      total revenue from sales of therapies
                42,052           
      research and development costs
                -28,449 -107,691   -20,150 -18,581 -20,072 -16,798 -16,471 -19,885  
      income before taxation
                -16,461    -8,272 -17,783 -25,438.25 -32,259 -35,775 -33,719  
      other comprehensive income
                           
      other comprehensive income that is or may be reclassified to profit or loss in subsequent periods:
                           
      total other comprehensive income for the period
                380           
      total comprehensive loss for the period
                -16,317    -6,444 -15,923 -23,056.5 -30,172 -33,000   
      basic and diluted loss per share - £
                -0.35    -0.14 -0.37 -0.91 -0.69 -0.75 -0.76  
      net other operating income
                         
      non-operating expense
                 -5,481 -318 -1,322 -1,279 -1,323 -1,343 -1,309 -1,276   
      basic and diluted loss per share
                 -1.09          
      net other operating expense
                           
      basic earnings per share - / £
                   0.14        
      diluted earnings per share - / £
                   0.13        
      net other operating income /
                       40   
      other comprehensive loss
                           
      other comprehensive loss that is or may be reclassified to profit or loss in subsequent periods:
                           
      total other comprehensive loss for the period
                    -323       
      other comprehensive income /
                           
      other comprehensive income / (loss) that is or may be reclassified to profit or loss in subsequent periods:
                           
      total other comprehensive income / (loss) for the period
                     205      
      revenue
                      6,593 5,924 5,733 8,270  
      net other operating (expense) / income
                      -17.5 -28  -82  
      administrative expenses
                      -24,366 -20,048 -23,801 -20,184  
      other comprehensive (loss) / income
                           
      other comprehensive (loss) / income that is or may be reclassified to profit or loss in subsequent periods:
                           
      total other comprehensive (loss) / income for the period
                      -23 -38 -38   
      other comprehensive income that are or may be reclassified to profit or loss in subsequent periods:
                           
      non-operating (expense) / income
                         -1,838  
      other comprehensive income that are or may be reclassified to profit or loss in subsequent periods
                           
      total other comprehensive (loss) / income for the period, net of tax
                         -92  
      total comprehensive loss for the period, net of tax
                         -29,130  
    Balance Sheets:
    Quarterly
    Annual
      Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-11-07 2023-09-30 2023-06-30 2023-05-10 2023-03-31 2022-12-31 2022-11-09 2022-09-30 2022-08-09 2022-06-30 2022-05-11 2022-03-31 2022-03-03 2022-03-01 2021-12-31 2021-11-10 2021-09-30 2021-08-11 2021-06-30 2021-03-31 2020-12-31 
                                     
        assets
                                     
        current assets
                                     
        cash and cash equivalents
      452,675,000 467,709,000 498,413,000 487,933,000 476,845,000 455,731,000 537,767,000 504,985,000 832,821,000 442,626,000 363,955 363,955 342,341 337,461 337,461 332,539 347,189 347,189 208,064 208,064 205,853 205,853 237,886,000 332,539 237,886 256,551 256,551 278,870 278,870 313,083 129,716 
        marketable securities
      392,221,000 396,444,000 393,940,000 394,878,000 360,185,000 364,645,000 363,515,000 354,612,000                        
        accounts receivable
      81,068,000 73,977,000 75,880,000 69,761,000 63,094,000 63,009,000 63,659,000 60,245,000 57,754,000 52,093,000                      
        prepaid expenses and other current assets
      69,590,000 50,055,000 48,960,000 44,270,000 41,697,000 41,033,000 36,446,000 33,555,000 31,296,000 29,600,000                      
        inventory
      8,253,000 6,742,000 5,655,000 5,456,000 6,804,000 5,446,000 4,518,000 3,462,000 4,167,000 4,501,000 1,857 1,857 1,891 882 882 943 854 854 535 535 496 496  943        
        total current assets
      1,003,807,000 996,742,000 1,022,848,000 1,002,298,000 948,625,000 929,864,000 1,005,905,000 956,859,000 926,038,000 528,820,000 415,692 415,692 395,055 385,908 385,908 391,881 403,521 403,521 257,103 257,103 243,384 243,384 262,726,000 391,881 262,726 289,871 289,871 311,496 311,496 339,519 152,931 
        property and equipment
      12,128,000 11,462,000 9,433,000 9,548,000 9,770,000 10,092,000 9,160,000 7,684,000 8,380,000 9,215,000                      
        operating lease right of use assets
      37,546,000 38,783,000 39,397,000 39,428,000 38,126,000 37,643,000 39,672,000 32,435,000 32,812,000 33,520,000                      
        other non-current assets
      18,614,000 20,282,000 16,489,000 17,036,000 17,132,000 17,117,000 17,238,000 16,276,000 15,996,000 14,473,000 8,846 8,846 7,895 7,033 7,033 7,342 6,749 6,749 6,243 6,243 5,955 5,955  7,342        
        total assets
      1,072,095,000 1,067,269,000 1,102,500,000 1,082,387,000 1,028,008,000 1,009,506,000 1,084,638,000 1,023,365,000 993,987,000 597,001,000 464,119 464,119 440,360 430,534 430,534 435,518 444,673 444,673 295,568 295,568 282,037 282,037 301,773,000 435,518 301,773 330,740 330,740 353,013 353,013 381,147 197,194 
        liabilities and shareholders’ equity
                                     
        current liabilities
                                     
        accounts payable
      30,157,000 24,364,000 22,956,000 23,856,000 29,105,000 25,100,000 19,721,000 19,947,000 15,501,000 17,798,000                      
        accrued expenses and other current liabilities
      207,388,000 219,744,000 144,937,000 143,785,000 118,341,000 185,534,000 197,224,000 163,762,000 138,549,000 119,835,000                      
        deferred revenue, current
      572,000 583,000 582,000 594,000                            
        operating lease liabilities, current
      1,996,000 2,006,000 1,878,000 1,843,000 1,717,000 1,547,000 1,097,000 1,387,000 1,243,000 1,388,000                      
        total current liabilities
      240,113,000 246,697,000 170,353,000 170,078,000 149,163,000 212,181,000 266,249,000 185,096,000 155,293,000 139,021,000 97,608 97,608 92,287 84,662 84,662 83,090 77,218 77,218 64,555 64,555 53,120 53,120 61,180,000 83,090 61,180 55,325 55,325 54,688 54,688 54,493 54,998 
        deferred revenue, non-current
      4,622,000 4,858,000 4,995,000 5,247,000 5,612,000 5,434,000 5,797,000 5,477,000 5,468,000 5,515,000                      
        operating lease liabilities, non-current
      40,027,000 41,556,000 41,397,000 42,561,000 40,748,000 40,162,000 41,271,000 33,445,000 33,986,000 34,633,000                      
        interest-bearing loans and borrowings
      393,660,000 393,125,000 392,587,000 392,060,000 391,530,000 391,013,000  438,121,000 437,544,000 48,011,000 38,484 38,484 37,116 38,677 38,677 39,500 45,563 45,563 41,536 41,536 38,370 38,370 37,226,000 39,500 37,226 37,280 37,280 36,135 36,135 36,437 36,654 
        total liabilities
      678,422,000 686,236,000 705,936,000 693,906,000 649,529,000 648,790,000 706,811,000 664,228,000 634,453,000 228,158,000 172,576 172,576 163,086 156,441 156,441 156,762 149,854 149,854 130,916 130,916 118,739 118,739 130,226,000 156,762 130,226 128,853 128,853 130,874 130,874 135,350 141,848 
        commitments and contingencies
                                     
        shareholders’ equity
                                     
        ordinary shares (voting), £0.002 par value, most recent authority to allot up to a maximum nominal value of £149,633 and shares as of march 31, 2026 and december 31, 2025, respectively, and 50,831,928 and 50,689,271 shares issued and outstanding as of march 31, 2026 and december 31, 2025, respectively.
      137,000                               
        deferred shares, £0.0001 par value...
      1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000 1,000                      
        additional paid-in capital
      1,247,212,000 1,240,255,000 1,227,649,000 1,215,997,000 1,202,171,000 1,190,104,000 1,180,854,000 1,174,147,000 1,163,872,000 1,149,643,000                      
        accumulated deficit
      -818,304,000 -831,275,000 -801,215,000 -801,038,000 -790,738,000 -795,761,000 -771,990,000 -780,726,000 -769,110,000 -744,674,000 -290,123 -290,123 -292,027 -277,950 -277,950 -261,253 -236,050 -236,050 -242,278 -242,278 -497,520 -497,520 -481,392,000 -261,253 -481,392 -442,003 -442,003 -411,869 -411,869 -378,907 -349,869 
        accumulated other comprehensive loss
      -35,373,000 -28,084,000 -30,006,000 -26,614,000 -33,090,000 -33,763,000 -31,173,000 -34,420,000 -35,364,000 -36,261,000                      
        total shareholders' equity
      393,673,000  396,564,000 388,481,000 378,479,000  377,827,000 359,137,000                        
        total liabilities and shareholders' equity
      1,072,095,000  1,102,500,000 1,082,387,000 1,028,008,000  1,084,638,000 1,023,365,000                        
        tax receivable
       1,815,000            2,365 2,365 11,688 14,510 14,510 13,231 13,231 11,289 11,289 9,632,000 11,688 9,632 22,555 22,555 20,428 20,428 17,615 12,935 
        deferred tax assets
        14,333,000 14,077,000 14,355,000 14,790,000 12,663,000 10,111,000 10,761,000 10,973,000                      
        ordinary shares (voting and non-voting), £0.002 par value, most recent authority to allot up to a maximum nominal value of £149,633 and £97,454 shares as of december 31, 2025 and 2024, respectively, and 50,689,271 and 50,064,860 shares issued and outstanding as of december 31, 2025 and 2024, respectively.
       136,000                              
        total shareholders’ equity
       381,033,000    360,716,000   359,534,000 368,843,000                      
        total liabilities and shareholders’ equity
       1,067,269,000    1,009,506,000   993,987,000 597,001,000                      
        accrued expenses, non-current
        96,604,000 83,960,000 62,476,000  3,006,000 2,089,000 2,162,000 978,000                      
        ordinary shares (voting and non-voting), £0.002 par value, most recent authority to allot up to a maximum nominal value of £149,633 and £97,454 shares as of september 30, 2025 and december 31, 2024, respectively, and 50,467,954 and 50,064,860 shares issued and outstanding as of september 30, 2025 and december 31, 2024, respectively.
        135,000                             
        ordinary shares (voting and non-voting), £0.002 par value, most recent authority to allot up to a maximum nominal value of £149,633 and £97,454 shares as of june 30, 2025 and december 31, 2024, respectively, and 50,372,068 and 50,064,860 shares issued and outstanding as of june 30, 2025 and december 31, 2024, respectively.
         135,000                            
        ordinary shares (voting and non-voting), £0.002 par value, most recent authority to allot up to a maximum nominal value of £97,234 and £97,454 shares as of march 31, 2025 and december 31, 2024, respectively, and 50,184,609 and 50,064,860 shares issued and outstanding as of march 31, 2025 and december 31, 2024, respectively.
          135,000                           
        ordinary shares (voting and non-voting), £0.002 par value, most recent authority to allot up to a maximum nominal value of £97,454 and £109,355 shares as of december 31, 2024 and 2023, respectively, and 50,064,860 and 49,725,649 shares issued and outstanding as of december 31, 2024 and 2023, respectively.
           135,000                          
        interest-bearing loans and borrowings, current
            48,207,000                         
        interest-bearing loans and borrowings, non-current
            390,488,000                         
        ordinary shares (voting and non-voting), £0.002 par value, most recent authority to allot up to a maximum nominal value of £97,454 and £109,355 shares as of september 30, 2024 and december 31, 2023, respectively, and 50,025,620 and 49,725,649 shares issued and outstanding as of september 30, 2024 and december 31, 2023, respectively.
            135,000                         
        ordinary shares (voting and non-voting), £0.002 par value, most recent authority to allot up to a maximum nominal value of £97,454 and £109,355 shares as of june 30, 2024 and december 31, 2023, respectively, and 50,017,606 and 49,725,649 shares issued and outstanding as of june 30, 2024 and december 31, 2023, respectively.
             135,000                        
        ordinary shares (voting and non-voting), £0.002 par value, most recent authority to allot up to a maximum nominal value of £97,454 and £109,335 shares as of march 31, 2024 and december 31, 2023, respectively, and 50,006,085 and 49,725,649 shares issued and outstanding as of march 31, 2024 and december 31, 2023, respectively.
              135,000                       
        ordinary shares (voting and non-voting), £0.002 par value, most recent authority to allot up to a maximum nominal value of £109,335 shares as of december 31, 2023 and 2022, 49,725,649 and 48,088,346 shares issued and outstanding as of december 31, 2023 and 2022, respectively.
               134,000                      
        non-current assets
                                     
        property, plant and equipment
                8,025 8,025 8,325 8,156 8,156 6,472 6,580 6,580 7,092 7,092 7,849 7,849 8,944,000 6,472 8,944 10,043 10,043 10,988 10,988 12,321 13,754 
        intangible assets
                1,589 1,589 410 410 410 410        410        
        right of use assets
                25,832 25,832 24,233 24,742 24,742 25,173 23,963 23,963 21,853 21,853 22,199 22,199 22,593,000 25,173 22,593 22,772 22,772 22,391 22,391 22,742 23,093 
        deferred tax asset
                4,135 4,135 4,442 4,285 4,285 4,240 3,860 3,860 3,277 3,277 2,650 2,650 2,575,000 4,240 2,575 2,257 2,257 2,192 2,192 2,213 2,230 
        total non-current assets
                48,427 48,427 45,305 44,626 44,626 43,637 41,152 41,152 38,465 38,465 38,653 38,653 39,047,000 43,637 39,047 40,869 40,869 41,517 41,517 41,628 44,263 
        trade and other receivables
                49,880 49,880 48,458 45,200 45,200 46,711 40,968 40,968 35,273 35,273 25,746 25,746 15,208,000 46,711 15,208 10,765 10,765 12,198 12,198 8,821 10,280 
        equity
                                     
        share capital
                99 99 98 97 97 97 96 96 88 88 88 88 88,000 97 88 88 88 88 88 88 
        share premium
                146,205 146,205 137,957 128,744 128,744 123,751 120,147 120,147 579 579 212,499 212,499 212,238,000 123,751 212,238 211,930 211,930 211,286 211,286 211,286 386,230 
        foreign currency translation reserve
                -4,266 -4,266 -1,663 -2,717 -2,717 -3,097 -1,759 -1,759 -29 -29 294 294 89,000 -3,097 89 71 71 33 33 71 163 
        other reserves
                337,847 337,847 337,847 337,847 337,847 337,847 337,847 337,847 337,847 337,847 386,167 386,167 386,167,000 337,847 386,167 386,167 386,167 386,167 386,167 386,167  
        share-based payment reserve
                101,781 101,781 95,062 88,072 88,072 81,411 74,538 74,538 68,445 68,445 61,770 61,770 54,357,000 81,411 54,357 45,634 45,634 36,434 36,434 27,092 18,821 
        total equity
                291,543 291,543 277,274 274,093 274,093 278,756 294,819 294,819 164,652 164,652 163,298 163,298 171,547,000 278,756 171,547 201,887 201,887 222,139 222,139 245,797 55,346 
        non-current liabilities
                                     
        non-current accruals
                2,531 2,531 1,646 824 824 1,479        1,479        
        deferred revenue
                4,331 4,331 4,331 4,331 4,331 4,331     2,136 2,136 6,408,000 4,331 6,408 10,681 10,681     
        lease liabilities
                29,469 29,469 27,570 27,822 27,822 28,248 26,965 26,965 24,738 24,738 25,043 25,043 25,355,000 28,248 25,355 25,486 25,486 24,923 24,923 25,035 25,190 
        provisions
                153 153 136 125 125 114 108 108 87 87 70 70 57,000 114 57 81 81 175 175 160 138 
        total non-current liabilities
                74,968 74,968 70,799 71,779 71,779 73,672 72,636 72,636 66,361 66,361 65,619 65,619 69,046,000 73,672 69,046 73,528 73,528 76,186 76,186 80,857 86,850 
        trade and other payables
                93,135 93,135 85,754 78,158 78,158 75,076 64,928 64,928 48,133 48,133 34,695 34,695 35,436,000 75,076 35,436 28,815 28,815 27,027 27,027 26,359 25,728 
        corporation tax liability
                367 367 803                   
        total equity and liabilities
                464,119 464,119 440,360 430,534 430,534 435,518 444,673 444,673 295,568 295,568 282,037 282,037 301,773,000 435,518 301,773 330,740 330,740 353,013 353,013 381,147 197,194 
        tax credits receivable
                  2,365                   
        investment in sub-lease
                               188 188 470 470 540 776 
        other non-current financial assets
                            4,935,000  4,935 5,609 5,609 5,476 5,476 3,812 4,410 
        deferred liabilities
                                 14,953 14,953 19,225 24,868 
        embedded derivative assets
                                     
        tax payable
                                     
        derivative liabilities
                                     
      Cashflow Statements:
      Quarterly
      Annual
        Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-05-10 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-05-11 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 
                               
          cash flows from operating activities
                               
          net income
        12,971,000    5,023,000                   
          adjustments for:
                               
          share-based compensation expense
        6,302,000 8,339,000 9,837,000 10,033,000 9,489,000 8,667,000 6,559,000 10,000,000 8,964,000               
          depreciation
        948,000 834,000 798,000 780,000 854,000 1,166,000 1,035,000 992,000 1,011,000 4,086,031 1,368 1,316 1,285 1,285 1,337 1,477 1,638 1,679 1,679     
          unrealized foreign exchange gains
        -3,490,000                       
          unrealized gains on marketable securities
        -1,776,000 -4,504,000 -5,062,000 -4,693,000 -5,469,000 -1,062,000 -8,902,000                 
          non-cash lease expense
        627,000 667,000 567,000 568,000 546,000 560,000 488,000 432,000 432,000               
          other
        534,000 537,000 527,000 540,000 509,000 303,000 584,000 953,000 -2,000 411,989 198 -169 -18 -18 68 130 -130 -1 -1     
          changes in assets and liabilities:
                               
          decrease in accounts receivable
        -7,930,000    836,000                   
          increase in prepayments and other current assets
        -18,772,000    -28,000                   
          increase in accounts payable
        5,974,000 1,418,000 -287,000 -6,929,000 3,342,000 5,884,000 -776,000                 
          decrease in accrued expenses
        -8,303,000                       
          decrease in deferred revenue
        -146,000 -144,000 -146,000         -1,602 -1,602 58 -4,272 -4,272 -11,633 -11,633     
          increase in operating lease liabilities
        -864,000    756,000                   
          decrease in other operating assets
        150,000                       
          net cash from operating activities
        -13,775,000 -32,655,000 -4,456,000 25,964,000 435,000 -13,951,000 21,127,000 23,472,000 -4,587,000 2,928,481  -2,391 8,792  6,032 8,094 -9,184 -30,833 -30,833 -16,332 -21,203 -32,596 -25,979 
          capital expenditures
        -1,781,000 -748,000 -414,000 -298,000 -828,000 -331,000  -5,421,224  -768 -2,470  -918 -394 -337 -138 -138 -278 -374 -136 -220 
          free cash flows
        -15,556,000 -32,655,000 -5,204,000 25,550,000 137,000 -13,951,000 20,299,000 23,141,000  -2,492,743  -3,159 6,322  5,114 7,700 -9,521 -30,971 -30,971 -16,610 -21,577 -32,732 -26,199 
          cash flows from investing activities
                               
          proceeds from sale of marketable securities
        6,000,000 2,000,000 6,000,000 10,000,000                   
          purchase of property and equipment
        -1,781,000  -748,000 -414,000 -298,000  -828,000 -331,000 -430,000               
          net cash from investing activities
        4,219,000 -880,000 5,252,000 -30,414,000 9,702,000 -3,540,000 -828,000 -350,331,000 -430,000               
          cash flows from financing activities
                               
          proceeds from exercise of share options
        656,000  1,866,000 3,670,000 2,551,000  198,000 298,000 5,754,000               
          net cash from financing activities
        656,000 4,284,000 1,866,000 3,670,000 2,551,000 -51,511,000 198,000 -818,000 396,012,000               
          increase in cash and cash equivalents
        -8,900,000          13,678 7,673 10,883   125,812  -32,298      
          net foreign exchange difference on cash held
        -6,134,000 -1,453,000 7,818,000 11,868,000 8,426,000 -13,034,000 12,285,000 -159,000 -800,000 8,293,818 7,936 -2,793 -5,961 -5,961   12,142 265 265 -8 100 -24 -52 
          cash and cash equivalents at beginning of period
        467,709,000  455,731,000  442,626,000               
          cash and cash equivalents at end of period
        452,675,000  10,480,000 11,088,000 476,845,000  32,782,000 -327,836,000 832,821,000               
          supplemental disclosure of cash flow and noncash information
                               
          cash paid for interest
        -5,031,000  -5,032,000                     
          cash paid for income taxes, net of refunds
        -13,000  -2,075,000                     
          net loss
         -30,060,000 -177,000   -23,771,000 8,736,000 -11,616,000 -24,436,000               
          unrealized foreign exchange losses
           2,300,000 -2,907,000   100,000 1,304,000               
          loss on loan extinguishment
                               
          deferred income taxes
                               
          increase in accounts receivable
         1,994,000 -5,989,000   -1,295,000 -2,192,000 -2,663,000 -6,198,000               
          decrease in prepayments and other current assets
             -5,690,000 -1,852,000 -2,239,000 -1,819,000               
          increase in accrued expenses
         -22,031,000 15,133,000 33,730,000 -10,943,000 -1,226,000 26,697,000 26,862,000 19,169,000               
          decrease in operating lease liabilities
               -646,000 -490,000               
          increase in other operating assets
         -4,706,000   -1,573,000 -3,533,000   -1,395,000               
          decrease in other operating liabilities
                               
          proceeds from sale of property, plant and equipment
                      13   
          purchase of marketable securities
                           
          purchase of property, plant and equipment
                 -5,421,224 -538 -768 -2,470 -2,470 -918 -394 -337 -138 -138 -278 -374 -136 -220 
          proceeds from issue of ordinary shares
                               
          exercise of share options
                 34,323,544 8,249 9,214 4,993 4,993 3,605 3,152 1,123 261 261     
          loan repayments
                               
          debt prepayments and extinguishments
                               
          non-current interest-bearing loan received
                               
          debt issuance payments
                               
          increase in net cash and cash equivalents
           -780,000 12,688,000 -69,002,000 20,497,000 -327,677,000 390,995,000              183,419 
          cash and cash equivalents at beginning of year
                               
          cash and cash equivalents at end of year
                               
          supplemental cash flow information
                               
          cash received for interest
            -5,031,000 -16,520,000 -4,832,000 6,976,000 5,141,000               
          cash paid for income taxes
            -32,000 -158,000 -293,000 81,000 -140,000               
          increase in other operating liabilities
              816,000 -61,000 1,193,000               
          proceeds from issue of convertible senior notes
                              
          payments for debt issuance costs
              -1,116,000 -12,242,000               
          purchases of property and equipment in accounts payable
                               
          proceeds from issue of convertible loan notes
                402,500,000               
          supplemental disclosure of cash flow information
                               
          supplemental disclosure of cash flow and non-cash information
                               
          debt issuance costs in accrued expenses and other current liabilities
                -1,116,000               
          purchases of property and equipment in accrued expenses and other current liabilities
                               
          decrease in accounts payable
                -2,320,000               
          cash received for income taxes
                               
          loss for the period
                  1,904 -14,077 -16,697 -16,697  6,228 -6,121 -16,128 -16,128  -30,134 -32,962 -29,038 
          equity settled share-based payment expense
                  6,719 6,990 6,661 6,661  6,093 6,675 7,413 7,413     
          net finance (income) / costs
                  -2,459 -1,847 -926 -926          
          foreign exchange movements
                  -9,656 3,381 5,725 5,725          
          income tax charge /
                  -144 151 236 236          
          working capital adjustments:
                               
          increase in trade and other receivables and other non-current assets
                  -1,332             
          increase in trade and other payables
                  6,540 10,066 2,111  11,246 16,027 12,281 -807  6,384   631 
          decrease in current and non-current deferred revenue
                  -1,602             
          other working capital movements
                  923 -186 -562 -562 1,384 -159 -168 -480 -480     
          cash from operations
                  2,459 -2,391 -935 -935 6,036     -28,716 -21,203   
          r&d tax credits received
                  2,662             
          taxation paid
                  -3 -177 -177          
          purchase of intangible assets
                               
          interest income receipts
                  3,857             
          net cash flows from investing activities
                   2,706 -394  332        25 
          gross proceeds from issue of share capital
                          226,528 
          costs from issue of share capital
                          -15,543 
          interest paid
                  -1,518 -1,458 -2,101 -2,101          
          repayment of lease liabilities
                  -312 -398 -407 -407 -943 -816 -694 -755 -755 -694 -864 -799 -802 
          net cash flows from financing activities
                  6,419 7,358 2,485  -1,191 117,515     -1,070 -1,612 209,373 
          cash and cash equivalents at beginning of the period
                  332,539 332,539        129,716 
          cash and cash equivalents at end of the period
                  21,614 4,880 337,461 337,461  139,125 2,211 205,853 205,853  -22,319 -34,213 313,083 
          net cash from / (used in) operating activities
                     8,792          
          net cash flows from / (used in) investing activities
                               
          decrease in receivables and other non-current assets
                    2,852     -11,489      
          taxation received
                    9,904 9,904          
          interest received
                    2,076 2,076          
          decrease / (increase) in receivables and other non-current assets
                     2,852          
          increase / (decrease) in trade and other payables
                     2,111          
          net cash flows used in investing activities
                     -394          
          net cash flows from / (used in) financing activities
                     2,485          
          increase / (decrease) in cash and cash equivalents
                     10,883          
          loss for the year
                               
          equity settled share-based payment expenses
                           8,723 9,200 9,342 8,596 
          net finance costs
                      748 1,188 1,279 1,323 1,323 1,343 1,309   
          income tax credit
                      2,129 -1,244 -2,151 -1,655 -1,655 214 -2,125 -2,813 -4,681 
          increase in receivables and other non-current assets
                      -7,069 -5,070        
          net taxation received
                               
          proceeds from investment in sub-leases
                           228 76 245 
          other investing activities
                      1,660 597        
          repayment of principal loan liability
                               
          early settlement and other loan fees
                               
          interest paid on non-current interest-bearing loans
                               
          cash and cash equivalents at beginning of the year
                      237,886 237,886    
          cash and cash equivalents at end of the year
                               
          foreign exchange differences
                       -11,690 -9,753 945 945     
          net taxation paid
                               
          interest paid on non-current interest-bearing loan
                       -1,245 -967 -838 -838 -1,674 -850 -813 -810 
          net foreign exchange difference on cash
                               
          cash flows used in investing activities
                               
          (decrease) / increase in cash and cash equivalents
                          -32,298     
          net cash flows (used in) / generated by investing activities
                         -133 -133     
          net cash flows (used in) / generated by financing activities
                         -1,332 -1,332     
          (increase) / decrease in receivables and other non-current assets
                          -11,489     
          (decrease) / increase in trade and other payables
                          -807     
          depreciation of property, plant and equipment
                           1,317 1,336 1,398 1,460 
          depreciation of right of use assets
                           401 377 376 347 
          remeasurement of leases
                               
          amortization of intangible assets
                               
          write-off of intangible assets
                               
          loss on disposal of property, plant and equipment
                           -2  -9 191 
          profit on derecognition of leases
                               
          unrealized foreign exchange differences
                               
          decrease in trade and other receivables
                              2,068 
          movement in provisions and other charges
                           -129 -64 15 28 
          decrease in deferred liabilities
                           -4,275 -5,215   
          bank interest received on cash and cash equivalents
                             
          leasehold incentive
                               
          net cash flows (used in) from investing activities
                               
          cash flows from financing activities - sum
                               
          remeasurement of right of use assets
                               
          foreign exchange loss
                            936   
          increase in trade and other receivables
                            1,300   
          net income tax credit received
                               
          lease capital contribution
                               
          loss / (gain) on disposal of property, plant and equipment
                               
          increase/(decrease) in cash and cash equivalents
                               
          foreign exchange (gain) / loss
                               
          net finance costs/
                              1,838 
          foreign exchange translation differences
                              -368 
          increase in deferred liabilities
                              -7,051 
          gross gain from sale of equity investment
                               
          taxation charge
                               
          gross proceeds from disposal of equity investment
                               
          proceeds from sub-leases
                               
          net cash flows from / (used) in investing activities