7Baggers
Quarterly
Annual
    Unit: USD2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-09-30 2014-06-30 2014-03-31 
      
                                                  
      operating activities
                                                  
      net income
    -32,250,000 -34,070,000 -37,621,000 -52,153,000 -47,678,000 -38,427,000 -48,004,000 -44,122,000 -45,170,000 -52,755,000 -18,881,000 -56,363,000 -83,563,000 -76,105,000 -65,690,000 -68,621,000 -43,308,000 -55,133,000 -45,089,000 -53,111,000 -58,684,000 -28,072,000 -33,520,000 -28,302,000 -26,609,000 -23,478,000 -19,760,000 -16,027,000 -16,782,000 -19,654,000 -14,135,000 -12,497,000 -10,684,000 -9,645,000 -10,126,000 -7,940,000 -8,737,000 -8,408,000 -8,377,000 -7,446,000 -6,886,000 -7,779,000 -7,881,000 -6,603,000 -6,067,000 -6,980,000 
      adjustments to reconcile net income to net cash from operating activities:
                                                  
      depreciation and amortization
    3,227,000 3,278,000 3,333,000 4,813,000 4,607,000 4,721,000 4,821,000 4,885,000 4,740,000 4,466,000 4,191,000 4,842,000 3,193,000 2,962,000 2,761,000 2,206,000 1,519,000 1,166,000 959,000 861,000 773,000 748,000 705,000 623,000 587,000 543,000 440,000 327,000 310,000 281,000 286,000 290,000 244,000 231,000 206,000 203,000 218,000 233,000 227,000 210,000 187,000 162,000 128,000 115,000 133,000 123,000 
      stock-based compensation
    4,861,000 7,154,000 7,381,000  11,765,000 9,630,000 10,981,000  10,104,000 12,897,000 10,983,000  19,468,000 20,542,000 19,331,000  13,540,000 13,254,000 12,976,000  7,843,000 7,236,000 6,913,000  4,573,000 4,386,000 3,868,000  1,642,000 1,485,000 1,382,000  871,000 973,000 867,000  782,000 786,000 797,000  574,000 738,000 608,000 527,000 424,000 871,000 
      accretion and amortization of premiums and discounts on investments
    -810,000 -847,000 -1,068,000 -1,530,000 -2,196,000 -2,723,000 -2,631,000 -2,906,000 -3,257,000 -2,940,000 -2,295,000 -1,245,000 -409,000 525,000 873,000 1,072,000 1,366,000 1,489,000 1,140,000 855,000 303,000 247,000 271,000 80,000                       
      deferred revenue
    4,000 -212,000 -181,000 -207,000 -160,000 -525,000 -425,000 -820,000 192,000 -40,488,000 -5,422,000 -3,752,000 6,290,000 -3,497,000 -7,502,000 -5,849,000 -2,101,000 -3,107,000 666,000 -2,816,000 63,268,000 -515,000 -1,301,000 -2,430,000 -2,663,000 -2,132,000 3,838,000 9,474,000 -527,000 -526,000 -526,000 -526,000 -527,000 -526,000 -526,000 -526,000 -527,000 -822,000 -576,000 -180,000      
      change in fair value of stock price appreciation milestones
    90,000 73,000 -280,000 -670,000 13,000 -1,556,000 1,394,000 645,000 -1,049,000 -393,000 -1,718,000 -5,176,000 -891,000 -5,881,000 -8,359,000 -464,000 -11,026,000 8,700,000 -744,000 20,058,000                           
      (gain) loss on disposal of property and equipment
                                                  
      changes in operating assets and liabilities:
                                                  
      accounts receivable
    713,000 1,010,000 1,134,000 588,000 -2,479,000 -190,000 968,000 -288,000 1,296,000 10,666,000 24,980,000 -28,257,000 2,903,000 724,000 -5,174,000 -1,365,000 2,993,000 -3,358,000 -1,430,000 -2,272,000 -1,526,000       -500,000                
      prepaid expenses and other assets
    1,026,000 -786,000 3,925,000 -57,000 4,216,000 -3,487,000 4,565,000 -1,636,000 -1,465,000 4,076,000 11,901,000 -7,406,000 -2,788,000 -5,729,000 -2,407,000 -1,131,000 -252,000 -368,000 -1,301,000 -1,378,000 584,000 -13,424,000 636,000 -2,778,000 348,000 -273,000 792,000                    
      accounts payable and accrued expenses
    -550,000 484,000 -9,826,000 655,000 1,871,000 320,000 -4,507,000 -1,893,000 -2,281,000 -4,373,000 -20,393,000 3,387,000 10,279,000 4,079,000 -3,493,000 -10,380,000 6,737,000 2,606,000 6,944,000 1,072,000 -7,430,000 8,120,000 -3,316,000 1,511,000 3,659,000 365,000 -1,258,000 336,000 1,175,000 2,070,000 673,000 1,554,000 -184,000 -536,000 1,677,000 217,000 176,000 378,000 790,000 -282,000 -97,000 587,000 269,000 228,000 -35,000 43,000 
      right-of-use assets and lease liabilities
    -685,000 -635,000 -606,000 -3,095,000 -480,000 -434,000 -412,000 -372,000 -371,000 -329,000 -336,000 -271,000 -270,000 -235,000 -52,000 11,000 -201,000 660,000 1,933,000 1,974,000 1,960,000 1,959,000 1,985,000 32,000 33,000 348,000 361,000                    
      net cash from operating activities
    -24,374,000 -24,587,000 -33,809,000 -27,799,000 -29,419,000 -32,306,000 -33,350,000 -36,637,000 -38,273,000 -28,493,000 -28,860,000 -75,389,000 -55,047,000 -53,159,000 -64,613,000 -70,293,000 -33,375,000 -32,106,000 -27,096,000 -20,664,000 -30,733,000 38,841,000 -26,673,000 -25,535,000 -19,838,000 -20,309,000 -17,493,000 -11,020,000 -3,556,000 -11,523,000 -12,551,000 -10,721,000 -9,857,000 -8,872,000 -7,455,000 -7,551,000 -7,516,000 -7,504,000 -7,252,000        
      capex
    -2,798,000 -1,024,000 -541,000 26,000 -581,000 37,000 -72,000 -181,000 -1,009,000 -2,199,000 -2,596,000 -7,610,000 -8,157,000 -12,037,000 -6,707,000 -17,620,000 -12,548,000 -14,808,000 -1,357,000 -1,969,000 57,000 -807,000 -727,000 -2,792,000 -1,513,000 -2,224,000 -264,000 -1,117,000 -724,000 -278,000 -184,000 -797,000 -362,000 -411,000 -155,000 -40,000 -33,000 -206,000 -178,000        
      free cash flows
    -27,172,000 -25,611,000 -34,350,000 -27,773,000 -30,000,000 -32,269,000 -33,422,000 -36,818,000 -39,282,000 -30,692,000 -31,456,000 -82,999,000 -63,204,000 -65,196,000 -71,320,000 -87,913,000 -45,923,000 -46,914,000 -28,453,000 -22,633,000 -30,676,000 38,034,000 -27,400,000 -28,327,000 -21,351,000 -22,533,000 -17,757,000 -12,137,000 -4,280,000 -11,801,000 -12,735,000 -11,518,000 -10,219,000 -9,283,000 -7,610,000 -7,591,000 -7,549,000 -7,710,000 -7,430,000        
      investing activities
                                                  
      proceeds from sale of property and equipment
    3,000                                              
      purchases of property and equipment
    -2,203,000 -1,362,000 -1,196,000 -98,000 -495,000 -51,000 -86,000 -181,000 -565,000 -2,199,000 -3,208,000 -6,677,000 -8,676,000 -10,129,000 -10,084,000 -18,369,000 -14,735,000 -13,619,000 -3,981,000 -2,272,000 -954,000 -636,000 -1,070,000 -2,590,000 -1,264,000 -1,795,000 -1,746,000                    
      purchases of investments
    -57,975,000 -50,813,000 -48,624,000 -38,005,000 -64,744,000 -128,666,000 -86,335,000 -49,966,000 -102,130,000 -92,262,000 -114,452,000 -107,102,000 -101,579,000 -63,949,000 -132,166,000 -173,447,000 -165,468,000 -99,337,000 -529,907,000 -185,007,000                           
      maturities of investments
    81,447,000 71,644,000 92,493,000 60,919,000 90,700,000 75,344,000 103,735,000 95,500,000 127,500,000 127,628,000 127,000,000 166,891,000 190,633,000 114,365,000 135,224,000 263,094,000 258,162,000 111,584,000 62,000,000 21,250,000 39,150,000 35,956,000 24,844,000                        
      net cash from investing activities
    21,272,000 19,591,000 42,673,000 22,816,000 25,461,000 -53,373,000 17,314,000 45,353,000 24,805,000 33,167,000 9,340,000 53,112,000 80,378,000 40,287,000 -7,026,000 71,278,000 77,959,000 -1,372,000 -471,888,000 -166,029,000 -54,141,000 35,320,000 23,774,000 -110,516,000 36,286,000 -91,977,000 8,754,000 16,383,000 13,276,000 13,722,000 -43,844,000 13,203,000 13,638,000 1,339,000 -38,376,000 5,978,000 458,000 5,794,000 -16,344,000        
      financing activities
                                                  
      issuance of common stock from equity incentive plans, net of issuance costs
       -4,000 299,000 -180,000 58,000 207,000 1,517,000 1,487,000 3,406,000 2,797,000 3,449,000 7,942,000 3,718,000 5,605,000 4,885,000 1,200,000 2,559,000 1,011,000  163,000 688,000 1,258,000  1,133,000 175,000 606,000  106,000 32,000 34,000  24,000 -4,000 147,000        
      proceeds from public offering of common stock, net of issuance costs
       -662,000 75,193,000         -31,000   -270,000   -136,000                -143,000      
      proceeds from issuance of pre-funded warrants, net of issuance costs
       19,996,000                                      
      proceeds from ft819 cirm award
       3,130,000                                          
      proceeds from ft836 cirm award
    2,475,000                                              
      net cash from financing activities
    2,475,000   3,130,000 1,274,000 95,488,000 -180,000 58,000 207,000 1,517,000 1,487,000 3,406,000 2,797,000 3,418,000 7,942,000 3,719,000 438,050,000 4,910,000 930,000 275,547,000 1,451,000 -13,723,000 161,705,000 688,000 1,258,000 1,904,000    43,239,000 8,387,000 -2,012,000 -2,170,000 53,083,000 8,287,000 -1,907,000 -1,726,000 -900,000 -533,000 36,961,000 75,000    
      net change in cash, cash equivalents and restricted cash
    -627,000 -3,671,000 8,864,000 -1,853,000 -3,958,000 -84,405,000 79,452,000 8,536,000 -13,468,000 4,732,000 -19,313,000 -20,760,000 26,818,000 -9,466,000 -68,842,000 4,403,000 52,526,000 -29,759,000 -60,934,000 -181,783,000 -83,944,000 349,708,000 -1,448,000 -149,774,000 178,153,000 -111,598,000 -7,481,000 7,267,000 147,085,000 3,355,000 -56,040,000 45,721,000 12,168,000              
      cash, cash equivalents and restricted cash at beginning of the period
    46,283,000  57,047,000  76,560,000  148,810,000  182,574,000 100,041,000 190,741,000 89,074,000              
      cash, cash equivalents and restricted cash at end of the period
    -627,000 -3,671,000 55,147,000  -3,958,000 -84,405,000 136,499,000  -13,468,000 4,732,000 57,247,000  26,818,000 -9,466,000 79,968,000  52,526,000 -29,759,000 121,640,000 -181,783,000 -83,944,000 349,708,000 98,593,000 -149,774,000 178,153,000 -111,598,000 183,260,000 7,267,000 147,085,000 3,355,000 33,034,000 45,721,000 12,168,000              
      supplemental schedule of noncash investing and financing activities
                                                  
      purchases of property and equipment in accounts payable
    -595,000 338,000 655,000 124,000 -86,000 88,000 14,000  -444,000 612,000 -933,000 519,000 -1,908,000 3,377,000 749,000 2,187,000 -1,189,000 2,624,000 303,000 1,011,000 -171,000 343,000 -202,000 -249,000 -429,000 1,482,000                    
      loss on disposal of property and equipment
                                                 
      accrued issuance costs included in additional paid-in-capital
          558,000                                        
      operating activities:
                                                  
      adjustments to reconcile net income to net cash from operating activities
                                                  
      stock–based compensation
                                                  
      amortization of collaboration contract costs
                                                  
      impairment of long-lived assets
                                                  
      grant income from ft516 cirm award
                                                  
      changes in assets and liabilities:
                                                  
      cash, cash equivalents and restricted cash at beginning of the year
                                                  
      cash, cash equivalents and restricted cash at end of the year
                                                  
      amortization of collaboration contract assets
            7,196,000  783,000 -331,000 1,094,000  1,106,000 979,000 623,000  616,000                          
      right-of-use assets obtained in exchange for lease obligations
                                                  
      grant income from 2018 cirm award
                                                  
      amortization of collaboration contract asset
                          168,000 187,000 162,000 164,000 107,000                    
      grant income from cirm award
           -4,000,000                                    
      right-of use assets obtained in exchange for lease obligations
               164,000    102,000 1,444,000  -127,000 418,000 47,808,000                        
      proceeds from private placement of common stock, net of issuance costs
                       -25,000                          
      proceeds from sale of common stock to collaboration partner, net of issuance costs
                                                
      proceeds from cirm award
                       50,000 440,000     1,370,000 1,140,000                  
      proceeds from public offering of common stock and issuance of pre-funded warrants, net of issuance costs
                      432,445,000                            
      amortization of debt discounts and debt issuance costs
                           68,000 15,000 17,000 15,000 19,000 19,000 19,000 19,000 19,000 19,000 19,000 24,000 28,000 33,000 38,000 40,000        
      principal repayments of long–term debt
                                                  
      supplemental disclosure of cash flow information
                                                  
      interest paid
                           1,353,000 312,000 317,000 309,000                    
      noncash interest expense
                            79,000 80,000 79,000 94,000 94,000 93,000 92,000 94,000 89,000 61,000 77,000 96,000 112,000 127,000 157,000 157,000 165,000 165,000 164,000 59,000 7,000 10,000 
      deferred rent
                               55,000 66,000 2,000 69,000 269,000 268,000 276,000 272,000 1,000 2,000 -3,000 -7,000        
      issuance of common stock for license agreement
                                                  
      principal repayments of long-term debt
                                                  
      issuance on common stock for license agreement
                                                  
      non-cash loss on extinguishment of debt
                                                  
      cash payments included in loss on extinguishment of debt
                                                  
      issuance of common stock from equity incentive plans, net of repurchases and issuance costs
                                            221,000      
      proceeds from private placement issuances of common stock, net of issuance costs
                                                  
      proceeds from private placement issuance of preferred stock, net of issuance costs
                                                  
      proceeds from long–term debt
                                                  
      payments of debt issuance costs
                                                  
      payments included in loss on extinguishment of debt
                                                  
      issuance of warrants for common stock in connection with long–term debt
                                                  
      purchases of short-term investments
                              -55,660,000 -39,971,000 -3,509,000 -16,166,000        
      maturities of short-term investments
                            37,550,000 16,000,000 10,500,000 17,500,000 14,000,000 14,000,000 12,000,000 14,000,000 14,000,000 1,750,000 1,750,000 6,000,000 4,000,000          
      amortization of premiums and discounts on investments
                             -298,000 -5,000 -36,000 -87,000 -137,000 -75,000 -4,000 -7,000 -13,000 -1,000 13,000 41,000 62,000 55,000        
      issuance costs from public offering of common stock
                                 -19,000 -251,000                
      cash flows from operating activities
                                                  
      issuance of common stock for license agreements
                                                 
      cash flows from investing activities
                                                  
      purchase of property and equipment
                               -1,117,000 -724,000 -278,000 -184,000 -797,000 -362,000 -411,000 -155,000 -40,000 -33,000 -206,000 -178,000        
      cash flows from financing activities
                                                  
      proceeds from public offerings of common stock, net of issuance costs
                               -245,000                   
      payments on long–term debt
                                                  
      prepaid expenses and other current assets
                                -222,000 -500,000 164,000  23,000 289,000 75,000  383,000 -190,000 -112,000  -87,000 72,000 303,000 164,000 52,000 304,000 
      issuance costs from private placement of common stock
                                    -65,000            
      issuance costs from private placement of preferred stock
                                    -128,000            
      proceeds from long-term debt
                                                  
      payments on long-term debt
                                    -6,709,000 -2,044,000 -2,011,000  -1,938,000 -1,903,000 -1,873,000        
      net cash provided (used) by financing activities
                                 1,156,000 355,000                
      loss on extinguishment of debt
                                                 
      proceeds from sale of common stock to collaboration partner
                                                
      payments for the issuance of debt
                                                  
      proceeds from private placement issuance of common stock, net of issuance costs
                                                  
      net change in cash and cash equivalents
                                      -48,001,000 51,510,000 1,229,000 -3,617,000 -25,322,000 -8,048,000 -8,319,000      
      cash and cash equivalents at beginning of the period
                                      88,609,000 64,809,000 49,101,000 54,036,000 
      cash and cash equivalents at end of the period
                                      40,608,000 51,510,000 1,229,000 -3,617,000 39,487,000 -8,048,000 -8,319,000 38,827,000 42,349,000 3,518,000 -5,869,000 47,881,000 
      stock–based milestone charges and change in fair value of exchangeable shares
                                                  
      issuances of common stock for technology
                                                  
      amortization of discounts
                                                6,000 8,000 
      change in fair value of preferred stock warrants
                                                  
      loss on disposal of assets
                                                  
      issuance of common stock, net of repurchases and issuance cost
                                                  
      issuance of convertible promissory notes
                                                  
      payment on convertible promissory note
                                                  
      beneficial conversion feature related to convertible notes
                                                  
      conversion of convertible preferred stock into common stock
                                                  
      conversion of convertible notes into common stock
                                                  
      exchange of exchangeable shares into common stock
                                                  
      warrant liability reclassification to equity
                                                  
      amortization of discounts and debt issuance costs
                                            45,000 43,000 44,000    
      stock-based milestone charges
                                                  
      stock-based milestone charges and change in fair value of exchangeable shares
                                               375,000 
      issuance of common stock, net of repurchases and issuance costs
                                              75,000 2,000   
      proceeds from (cost of) initial public offering, net of offering costs
                                                  
      restricted cash
                                                  
      repurchase of common stock for cash
                                                  
      proceeds from initial public offering, net of offering costs
                                                  
      issuance of preferred stock for cash, net of offering costs
                                                  
      consolidated net income
                                                  
      initial fair value and change in fair value of exchangeable shares
                                                  
      issuance of common stock, net of repurchases
                                                  
      costs paid in connection with initial public offering
                                                  
      proceeds from convertible promissory notes
                                                  
      issuance of convertible preferred stock, net of offering costs
                                                  
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