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Editas Medicine, Inc
(NASDAQ:EDIT) 

EDIT stock logo

Editas Medicine, Inc., a clinical stage genome editing company, focuses on developing transformative genomic medicines to treat a range of serious diseases. It develops a proprietary genome editing platform based on CRISPR technology to target genetically addressable diseases and therapeutic areas. ...

Founded: 2013
Full Time Employees: 208
Sector: Healthcare
Industry: Biotechnology

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At a glance:
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Income Statements:
Quarterly
Annual
    Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-09-03 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-09-03 2016-06-30 2016-03-31 2015-12-31 2015-09-03 
                                                 
      collaboration and other research and development revenues
    2,831,000 24,741,000 7,543,000 3,578,000 4,658,000 30,604,000 61,000 513,000 1,135,000 60,049,000 5,336,000 2,887,000 9,851,000 6,536,000 42,000 6,362,000 6,771,000 12,469,000 6,197,000 379,000 6,499,000 11,419,000 62,841,000 10,749,000 5,723,000 12,284,000 3,848,000 2,330,000 2,069,000 6,119,000 14,519,000 7,372,000 3,927,000 3,667,000 6,282,000  3,097,000 682,000 -3,526,000 962,000  3,388,000    
      operating expenses:
                                                 
      research and development
    17,600,000 27,404,000 19,775,000 16,181,000 26,593,000 48,611,000 47,639,000 54,210,000 48,787,000 69,556,000 40,512,000 29,779,000 37,804,000 51,998,000 41,326,000 43,659,000 37,976,000 37,553,000 29,265,000 33,753,000 41,937,000 61,504,000 33,916,000 28,007,000 34,570,000 34,789,000 22,702,000 23,565,000 15,842,000 19,194,000 17,443,000 32,718,000 21,300,000 26,424,000 20,396,000  17,318,000 19,021,000 -11,298,000 10,832,000  10,430,000 8,882,000   
      general and administrative
    10,234,000 11,353,000 12,316,000 12,859,000 13,375,000 16,354,000 18,088,000 18,206,000 19,339,000 14,455,000 14,987,000 17,202,000 23,008,000 17,984,000 16,236,000 16,937,000 19,545,000 16,526,000 16,185,000 22,027,000 21,445,000 15,787,000 19,936,000 14,081,000 17,769,000 16,917,000 15,734,000 14,414,000 17,489,000 13,178,000 13,334,000 14,311,000 14,186,000 13,685,000 12,635,000  11,894,000 12,288,000 -15,120,000 11,295,000  12,158,000 9,762,000   
      restructuring and impairment charges
     -6,261,000  26,082,000 40,853,000                                         
      total operating expenses
    27,834,000 32,496,000 32,091,000 55,122,000 80,821,000 77,197,000 65,727,000 72,416,000 68,126,000 84,011,000 55,499,000 46,981,000 60,812,000 69,982,000 57,562,000 60,596,000 57,521,000 54,079,000 45,450,000 55,780,000 63,382,000 77,291,000 53,852,000 42,088,000 52,339,000 51,706,000 38,436,000 37,979,000 33,331,000 32,372,000 30,777,000 47,029,000 35,486,000 40,109,000 33,031,000  29,212,000 31,309,000 -26,418,000 22,127,000  22,588,000 18,644,000   
      operating income
    -25,003,000 -7,755,000 -24,548,000 -51,544,000 -76,163,000 -46,593,000 -65,666,000 -71,903,000 -66,991,000 -23,962,000 -50,163,000 -44,094,000 -50,961,000 -63,446,000 -57,520,000 -54,234,000 -50,750,000 -41,610,000 -39,253,000 -55,401,000 -56,883,000 -65,872,000 8,989,000 -31,339,000 -46,616,000 -39,422,000 -34,588,000 -35,649,000 -31,262,000 -26,253,000 -16,258,000 -39,657,000 -31,559,000 -36,442,000 -26,749,000  -26,115,000 -30,627,000 22,892,000 -21,165,000  -19,200,000 -17,839,000   
      yoy
    -67.17% -83.36% -62.62% -28.31% 13.69% 94.45% 30.91% 63.07% 31.46% -62.23% -12.79% -18.70% 0.42% 52.48% 46.54% -2.11% -10.78% -36.83% -536.68% 76.78% 22.02% 67.09% -125.99% -12.09% 49.11% 50.16% 112.74% -10.11% -0.94% -27.96% -39.22%  20.85% 18.99% -216.85%   59.52% -228.33%       
      qoq
    222.41% -68.41% -52.37% -32.32% 63.46% -29.05% -8.67% 7.33% 179.57% -52.23% 13.76% -13.48% -19.68% 10.30% 6.06% 6.87% 21.97% 6.00% -29.15% -2.61% -13.65% -832.81% -128.68% -32.77% 18.25% 13.98% -2.98% 14.03% 19.08% 61.48% -59.00% 25.66% -13.40% 36.24%   -14.73% -233.79% -208.16%   7.63%    
      other income, net:
                                                 
      interest expense related to sale of future revenues
    -1,072,000 464,000 -2,399,000                                           
      interest income
    1,206,000 1,676,000 1,831,000 2,087,000 2,716,000 1,201,000 3,530,000 4,297,000 5,035,000 5,102,000 5,144,000 3,811,000 3,509,000 1,419,000 1,793,000 546,000 469,000 1,910,000 152,000 146,000 134,000 228,000 226,000 592,000 1,559,000 1,645,000 1,680,000 1,931,000 2,057,000 1,202,000 1,024,000 780,000 438,000 124,000 -46,000  -446,000 -610,000 -562,000 142,000  153,000 124,000   
      other expense
    -113,000 -5,000 -1,000          -1,584,000                              -30,000   
      total other income
    21,000 2,135,000 -569,000 -1,691,000 75,000 1,198,000 3,525,000 4,296,000 5,041,000 5,088,000 5,144,000 3,804,000 1,925,000 2,708,000 1,794,000 781,000 235,000 174,000 171,000 145,000 155,000 3,373,000 -1,170,000 7,767,000 8,892,000 1,652,000 1,647,000 1,863,000 2,013,000 1,198,000 1,020,000 934,000 620,000 253,000 150,000  -324,000 -470,000 -37,985,000 145,000  158,000 94,000   
      net income
    -24,982,000 -5,620,000 -25,117,000 -53,235,000 -76,088,000 -45,395,000 -62,141,000 -67,607,000 -61,950,000 -18,874,000 -45,019,000 -40,290,000 -49,036,000 -60,738,000 -55,726,000 -53,453,000 -50,515,000 -41,436,000 -39,082,000 -55,256,000 -56,728,000 -62,499,000 7,819,000 -23,572,000 -37,724,000 -37,770,000 -32,941,000 -33,786,000 -29,249,000 -25,055,000 -15,238,000 -38,723,000 -30,939,000 -36,189,000 -26,599,000  -26,439,000 -31,097,000 -15,093,000 -21,020,000  -19,042,000 -17,745,000   
      yoy
    -67.17% -87.62% -59.58% -21.26% 22.82% 140.52% 38.03% 67.80% 26.34% -68.93% -19.21% -24.63% -2.93% 46.58% 42.59% -3.26% -10.95% -33.70% -599.83% 134.41% 50.38% 65.47% -123.74% -30.23% 28.98% 50.75% 116.18% -12.75% -5.46% -30.77% -42.71%  17.02% 16.37% 76.23%   63.31% -14.95%       
      qoq
    344.52% -77.62% -52.82% -30.03% 67.61% -26.95% -8.08% 9.13% 228.23% -58.08% 11.74% -17.84% -19.27% 8.99% 4.25% 5.82% 21.91% 6.02% -29.27% -2.59% -9.23% -899.32% -133.17% -37.51% -0.12% 14.66% -2.50% 15.51% 16.74% 64.42% -60.65% 25.16% -14.51% 36.05%   -14.98% 106.04% -28.20%   7.31%    
      net income per share
    -0.26  -0.28 -0.63 -0.92 -0.55 -0.75 -0.82 -0.76 -0.21 -0.55 -0.56 -0.71 -0.88 -0.81 -0.78 -0.74 -0.61 -0.57 -0.81 -0.86 -1.05 0.13 -0.43 -0.69 -0.73 -0.66 -0.69 -0.6 -0.52 -0.32 -0.82 -0.67 -0.85 -0.64  -0.65 -0.85 -26.69 -0.59  -0.54 -0.8   
      weighted-average common shares outstanding, basic and diluted
    97,879,343 88,745,908 90,090,397 84,412,200 83,055,066 82,338,220 82,485,199 82,310,368 81,938,839 75,965,633 81,648,250 71,376,678 68,924,180 68,664,822 68,736,125 68,640,858 68,484,978 67,619,388  67,877,126 65,992,395 58,609,389  55,346,052 54,590,194 49,983,329 49,820,455 49,070,574 48,838,229 47,097,735 47,414,271 46,952,059 45,992,008 40,323,631 41,307,092 300,480 40,830,161 36,485,421 2,566,916 35,505,429 300,480 35,286,719 22,280,797   
      other income
       -1,758,000 -425,000  -5,000 -1,000 6,000 -14,000  -7,000  1,289,000 1,000 235,000 -234,000 -1,736,000 19,000 -1,000 21,000 3,145,000 -1,396,000 7,175,000 7,333,000 7,000 -33,000 -68,000 -44,000 -4,000  154,000 182,000 129,000 196,000  122,000 140,000 -5,500 3,000  5,000    
      interest related to sale of future revenues
       -2,020,000 -2,216,000                                         
      weighted-average common shares outstanding, basic
                      68,219,742    62,144,118                       
      weighted-average common shares outstanding, diluted
                      68,219,742    62,697,173                       
      reconciliation of net loss to net loss attributable to common stockholders:
                                                 
      accretion of redeemable convertible preferred stock to redemption value
                                          -347,000    -47,000   
      net loss attributable to common stockholders
                                     -36,189,000 -26,599,000  -26,439,000 -31,097,000 -15,440,000 -21,020,000  -19,042,000 -17,792,000   
      net loss and comprehensive loss
                                         -31,097,000 -15,093,000 -21,020,000  -19,042,000 -17,745,000   
      collaboration revenue
                                              805,000   
    Balance Sheets:
    Quarterly
    Annual
      Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 
                                                
        assets
                                                
        current assets:
                                                
        cash and cash equivalents
      123,648,000 146,645,000 165,648,000 138,542,000 138,692,000 131,541,000 95,832,000 64,441,000 69,227,000 123,652,000 82,537,000 220,817,000 129,021,000 141,522,000 210,704,000 169,401,000 210,881,000 203,519,000 259,884,000 337,834,000 354,918,000 139,682,000 279,576,000 485,819,000 232,850,000 238,183,000 104,772,000 210,605,000 157,932,000 134,776,000 111,701,000 131,924,000 217,671,000 146,630,000 86,542,000 144,096,000 351,552,000 185,323,000 199,874,000 217,650,000 229,204,000 143,180,000 
        accounts receivable
      2,592,000 15,176,000 8,130,000 588,000 510,000 16,266,000 126,000 244,000 245,000 10,187,000 2,422,000 2,286,000 242,000 5,145,000 120,000 713,000 1,371,000 267,000 251,000 331,000 672,000 6,048,000 1,055,000 1,865,000 1,832,000 418,000 311,000 12,000  30,000 43,000 362,000 931,000 679,000 695,000 820,000 945,000 88,000 1,122,000 1,195,000 1,108,000 1,019,000 
        prepaid expenses and other current assets
      1,826,000 2,074,000 3,113,000 3,707,000 3,369,000 3,136,000 5,925,000 6,998,000 9,139,000 7,531,000 6,564,000 6,724,000 5,777,000 7,335,000 6,892,000 8,106,000 7,298,000 7,198,000 9,516,000 5,408,000 6,311,000 10,929,000 10,467,000 9,541,000 8,281,000 6,286,000 6,284,000 6,298,000 5,002,000 5,791,000 5,018,000 3,795,000 3,060,000 2,381,000 2,030,000 2,257,000 1,289,000 1,772,000 2,453,000 2,373,000 1,874,000 786,000 
        total current assets
      128,066,000 163,895,000 176,891,000 182,796,000 224,843,000 289,315,000 271,139,000 286,354,000 305,555,000 340,829,000 358,603,000 440,978,000 324,458,000 356,754,000 426,629,000 461,377,000 497,031,000 507,310,000 567,608,000 616,292,000 632,316,000 419,087,000 506,827,000 610,126,000 425,106,000 463,844,000 339,211,000 324,240,000 347,067,000 374,776,000 342,553,000 348,237,000 362,812,000 332,199,000 298,416,000 327,872,000 353,786,000 187,183,000 203,449,000 221,218,000 232,186,000 144,985,000 
        property and equipment
      2,884,000 3,542,000 4,287,000 4,576,000 8,182,000 14,497,000 15,419,000 14,156,000 13,257,000 12,032,000 11,559,000 12,846,000 13,211,000 15,569,000 15,494,000 16,198,000 17,258,000 17,118,000 15,631,000 14,910,000 14,095,000 14,020,000 14,069,000 12,895,000 12,218,000 10,887,000 10,075,000 8,530,000 7,991,000 40,232,000 39,699,000 39,915,000 39,551,000 39,442,000 39,092,000 39,358,000 39,636,000 40,378,000 37,072,000 26,741,000 15,003,000 2,130,000 
        right-of-use assets
      15,412,000 16,121,000 17,583,000 19,011,000 26,429,000 32,554,000 35,728,000 36,951,000 31,443,000 33,680,000 31,936,000 34,811,000 36,344,000 43,648,000 22,532,000 20,666,000 23,457,000 26,173,000 27,801,000 30,314,000 29,305,000 25,128,000 26,398,000 28,569,000 27,022,000 28,761,000                 
        restricted cash and other non-current assets
      2,976,000 2,976,000 2,990,000 4,198,000 4,198,000 5,223,000 5,281,000 8,145,000 9,487,000 8,588,000 5,755,000 5,253,000 6,753,000 5,253,000 7,530,000 7,530,000 7,316,000 6,811,000 6,781,000 6,780,000 6,688,000 4,703,000 3,877,000 3,891,000 2,391,000 5,393,000 5,392,000 5,378,000 5,378,000 5,378,000 5,378,000 5,378,000 1,619,000 1,619,000 1,619,000 1,619,000 1,619,000 1,621,000 1,632,000 1,643,000 1,619,000  
        total assets
      149,338,000 186,534,000 201,751,000 210,581,000 263,652,000 341,589,000 327,567,000 384,801,000 440,347,000 499,153,000 504,650,000 541,953,000 464,105,000 514,321,000 531,029,000 580,833,000 623,108,000 677,483,000 717,019,000 755,880,000 780,294,000 572,602,000 597,157,000 655,481,000 466,737,000 508,885,000 372,359,000 355,625,000 378,916,000 420,386,000 387,630,000 393,530,000 403,982,000 373,260,000 339,127,000 368,849,000 395,041,000 229,182,000 242,153,000 249,602,000 248,808,000 149,363,000 
        liabilities and stockholders’ equity
                                                
        current liabilities:
                                                
        accounts payable
      4,332,000 2,605,000 3,163,000 6,723,000 5,465,000 5,493,000 12,491,000 13,769,000 7,966,000 8,269,000 10,411,000 8,066,000 9,047,000 9,511,000 6,836,000 6,169,000 4,693,000 5,050,000 3,402,000 4,415,000 8,910,000 6,408,000 5,158,000 6,339,000 10,394,000 5,843,000 6,624,000 3,981,000 6,557,000 5,327,000 5,040,000 4,661,000 8,996,000 4,020,000 6,976,000 8,156,000 15,233,000 4,640,000 3,718,000 5,844,000 2,909,000 1,381,000 
        accrued expenses
      21,248,000 32,610,000 47,522,000 48,068,000 47,488,000 45,859,000 28,785,000 27,669,000 31,481,000 34,563,000 30,278,000 27,896,000 31,560,000 31,296,000 19,259,000 20,105,000 15,787,000 20,192,000 14,575,000 18,627,000 15,132,000 24,046,000 20,307,000 10,194,000 8,669,000 22,120,000 8,138,000 8,169,000 5,642,000 12,813,000 11,341,000 11,029,000 7,767,000 11,049,000 8,450,000 11,160,000 6,769,000 17,439,000 9,492,000 7,846,000 7,251,000 5,456,000 
        liability for sale of future revenues, current
      7,500,000 5,000,000 5,000,000 5,000,000 5,000,000 5,000,000                                     
        operating lease liabilities, current
      6,699,000 6,031,000                                         
        total current liabilities
      39,779,000 46,246,000 61,773,000 65,937,000 73,114,000 77,225,000 72,353,000 74,306,000 66,487,000 63,217,000 58,603,000 54,513,000 57,155,000 60,110,000 42,289,000 36,421,000 36,503,000 46,884,000 50,907,000 66,016,000 64,010,000 58,208,000 54,816,000 68,150,000 68,869,000 59,963,000 66,787,000 72,867,000 41,029,000 35,900,000 26,086,000 24,020,000 30,994,000 36,707,000 29,496,000 48,686,000 50,287,000 33,083,000 13,757,000 13,721,000 10,222,000 6,925,000 
        operating lease liabilities, net of current portion
      10,598,000 12,071,000 13,564,000 14,989,000 17,972,000 20,380,000 22,095,000 20,514,000 21,783,000 24,372,000 24,918,000 26,856,000 28,810,000 32,864,000 9,328,000 10,110,000 12,957,000 16,069,000 18,430,000 21,282,000 21,621,000 19,324,000 20,368,000 22,153,000 21,530,000 23,277,000                 
        liability for sale of future revenues, net of current portion
      47,177,000 53,605,000                                         
        deferred revenue, net of current portion
      44,509,000 44,509,000 54,204,000 54,204,000 54,204,000 54,204,000 54,204,000 54,204,000 54,204,000 60,667,000 60,667,000 60,667,000 60,667,000 60,667,000 64,667,000 68,888,000 60,888,000 60,888,000 60,888,000 55,221,000 56,667,000 73,984,000 80,821,000 138,406,000 141,770,000 163,207,000 82,379,000 75,911,000 105,865,000 115,614,000 104,100,000 104,929,000 91,972,000 94,725,000 97,851,000 100,953,000 104,033,000 26,000,000     
        other non-current liabilities
      2,867,000 2,815,000 4,688,000 4,592,000 6,363,000 3,072,000 3,281,000 3,768,000 3,473,000 1,800,000            27,500,000   1,000 1,000 1,000 1,000 1,000 293,000 301,000 305,000 311,000 317,000 325,000 328,000 331,000 16,000 19,000 21,000 24,000 27,000 
        total liabilities
      144,930,000 159,246,000 188,298,000 191,392,000 201,232,000 207,315,000 151,933,000 152,792,000 145,947,000 150,056,000 144,188,000 142,036,000 146,632,000 153,641,000 116,284,000 115,419,000 110,348,000 123,841,000 130,225,000 142,519,000 142,298,000 179,016,000 156,005,000 228,709,000 232,170,000 246,448,000 162,369,000 162,563,000 161,754,000 184,224,000 163,181,000 162,198,000 156,467,000 165,180,000 161,339,000 183,845,000 188,580,000 94,575,000 71,977,000 62,272,000 47,445,000 32,562,000 
        stockholders’ equity
                                                
        preferred stock, 0.0001 par value per share...
                                                
        common stock, 0.0001 par value per share...
      10,000 10,000 9,000 9,000 8,000 8,000 8,000 8,000 8,000 8,000 8,000 8,000 7,000 7,000 7,000 7,000 7,000 7,000 7,000 7,000 7,000 6,000 6,000 6,000 5,000 5,000 5,000 5,000 5,000 5,000 5,000 5,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000 4,000  
        additional paid-in capital
      1,657,883,000 1,655,781,000 1,636,327,000 1,616,931,000 1,606,855,000 1,602,441,000 1,598,152,000 1,593,350,000 1,588,018,000 1,580,241,000 1,574,382,000 1,569,651,000 1,446,912,000 1,442,405,000 1,436,422,000 1,430,461,000 1,423,476,000 1,411,827,000 1,403,114,000 1,390,606,000 1,359,987,000 1,058,823,000 1,043,892,000 1,037,100,000 820,813,000 811,546,000 721,397,000 671,522,000 661,852,000 652,464,000 615,749,000 607,311,000 584,825,000 514,002,000 447,468,000 428,129,000 423,080,000 320,129,000 316,322,000 312,456,000 307,448,000 5,234,000 
        accumulated other comprehensive income
         15,000 88,000 268,000 522,000 -442,000 -326,000 198,000            -46,000 -48,000 183,000 694,000 107,000 39,000 45,000 29,000              
        accumulated deficit
      -1,653,485,000 -1,628,503,000 -1,622,883,000 -1,597,766,000 -1,544,531,000 -1,468,443,000 -1,423,048,000 -1,360,907,000 -1,293,300,000 -1,231,350,000 -1,212,476,000 -1,167,457,000 -1,127,167,000 -1,078,131,000 -1,017,393,000 -961,667,000 -908,214,000 -857,699,000 -816,263,000 -777,181,000 -721,925,000 -665,197,000 -602,698,000 -610,517,000 -586,945,000 -549,221,000 -511,451,000 -478,510,000 -444,724,000 -416,278,000 -391,223,000 -375,985,000 -337,262,000 -305,850,000 -269,661,000 -243,062,000 -216,623,000 -185,526,000 -146,150,000 -125,130,000 -106,089,000 -88,348,000 
        total stockholders’ equity
      4,408,000 27,288,000 13,453,000 19,189,000 62,420,000 134,274,000 175,634,000 232,009,000 294,400,000 349,097,000 360,462,000 399,917,000 317,473,000 360,680,000 414,745,000 465,414,000 512,760,000 553,642,000 586,794,000 613,361,000 637,996,000 393,586,000 441,152,000 426,772,000 234,567,000 262,437,000 209,990,000 193,062,000 217,162,000 236,162,000 224,449,000 231,332,000 247,515,000 208,080,000 177,788,000 185,004,000 206,461,000 134,607,000 170,176,000 187,330,000 201,363,000  
        total liabilities and stockholders’ equity
      149,338,000 186,534,000 201,751,000 210,581,000 263,652,000 341,589,000 327,567,000 384,801,000 440,347,000 499,153,000 504,650,000 541,953,000 464,105,000 514,321,000 531,029,000 580,833,000 623,108,000 677,483,000 717,019,000 755,880,000 780,294,000 572,602,000 597,157,000 655,481,000 466,737,000 508,885,000 372,359,000 355,625,000 378,916,000 420,386,000 387,630,000 393,530,000 403,982,000 373,260,000 339,127,000 368,849,000 395,041,000      
        marketable securities
         39,959,000 82,272,000 138,372,000 169,256,000 214,671,000 226,944,000 199,459,000 267,080,000 211,151,000 189,418,000 202,752,000 208,913,000 283,157,000 277,481,000 296,326,000 297,957,000 272,719,000 270,415,000 262,428,000 215,729,000 112,901,000 182,143,000 218,957,000 227,844,000 107,325,000 184,133,000 234,179,000 225,791,000 212,156,000 141,150,000 182,509,000 209,149,000 180,699,000       
        deferred revenue, current
          2,000,000 6,221,000 14,684,000 14,684,000 14,684,000 8,221,000 8,221,000 8,221,000 8,221,000 8,221,000 4,221,000  5,817,000 11,333,000 22,667,000 34,000,000 32,704,000 20,943,000 19,874,000 40,940,000 40,642,000 23,514,000 46,019,000 56,036,000 23,400,000 15,712,000 8,725,000 7,386,000 13,323,000 13,238,000 13,239,000 13,239,000       
        commitments and contingencies
                                                
        operating lease liabilities
        6,088,000 6,146,000 13,161,000 14,652,000 16,393,000 18,184,000 12,356,000 12,164,000 9,693,000 10,330,000 8,327,000 11,082,000 11,973,000 10,147,000 10,206,000 10,309,000 10,263,000 8,974,000 7,264,000 6,811,000 6,342,000 6,650,000 5,649,000 5,804,000                 
        liability for sale of future revenues - non-current
        54,069,000 51,670,000 49,579,000 52,434,000                                     
        accumulated other comprehensive loss
                -1,452,000 -2,285,000 -2,279,000 -3,601,000 -4,291,000 -3,387,000 -2,509,000 -493,000 -64,000 -71,000 -73,000         -29,000 -82,000  -52,000 -76,000 -23,000 -67,000       
        other current liabilities
                            3,135,000 4,027,000 3,515,000 2,682,000 1,558,000 1,033,000 1,911,000 2,048,000 980,000 944,000 908,000 900,000 831,000 1,131,000 13,285,000 986,000 547,000    
        construction financing lease obligation, net of current portion
                                   32,417,000 32,694,000 32,944,000 33,190,000 33,431,000 33,667,000 33,878,000 33,929,000 35,096,000 32,048,000    
        right-of-use asset
                                17,681,000 17,477,000 18,480,000              
        operating lease liability
                                4,448,000 3,648,000 3,519,000              
        operating lease liability, net of current portion
                                13,202,000 13,784,000 14,859,000              
        notes payable
                                       7,500,000  15,000,000 15,000,000 10,000,000     
        accumulated other comprehensive gain
                                     1,000           
        liabilities, redeemable convertible preferred stock and stockholders’ equity
                                                
        deferred rent, current portion
                                           18,000  31,000 62,000 88,000 
        deferred rent, net of current portion
                                           380,000 353,000 212,000 71,000  
        warrant to purchase redeemable securities
                                               289,000 
        series a-1 redeemable convertible preferred stock, 0.0001 par value per share...
                                               21,137,000 
        series a-2 redeemable convertible preferred stock, 0.0001 par value per share...
                                               59,027,000 
        series b redeemable convertible preferred stock, 0.0001 par value per share...
                                               119,751,000 
        total liabilities, redeemable convertible preferred stock and stockholders’ equity
                                           229,182,000 242,153,000 249,602,000 248,808,000  
        deferred revenue
                                            25,800,000 25,642,000 25,479,000 25,321,000 
        preferred stock, 0.0001 par value...
                                                
        construction financing lease obligation
                                             22,676,000 11,649,000  
        other non-current assets
                                               2,248,000 
        liabilities, redeemable convertible preferred stock and stockholders’ deficit
                                                
        anti-dilution protection liability
                                                
        preferred stock tranche liability
                                                
        equipment loan, current portion, net of discount
                                                
        equipment loan, net of current portion and discount
                                                
        stockholders’ deficit
                                                
        total stockholders’ deficit
                                               -83,114,000 
        total liabilities, redeemable convertible preferred stock and stockholders’ deficit
                                               149,363,000 
      Cashflow Statements:
      Quarterly
      Annual
        Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 
                                                 
          cash flow from operating activities
                                                 
          net loss
        -24,982,000 -5,620,000 -25,117,000 -53,235,000 -76,088,000  -62,141,000 -67,607,000 -61,950,000 -18,874,000 -45,019,000 -40,290,000 -49,036,000 -60,738,000 -55,726,000 -53,453,000 -50,515,000 -41,436,000 -39,082,000 -55,256,000 -56,728,000 -62,499,000 7,819,000 -23,572,000 -37,724,000 -37,770,000 -32,941,000 -33,786,000 -29,249,000 -25,055,000 -15,238,000 -38,722,000 -30,939,000 -36,189,000 -26,599,000 -26,439,000 -31,097,000 57,709,817 -21,020,000 -19,042,000 -17,745,000 
          adjustments to reconcile net loss to net cash from operating activities:
                                                 
          stock-based compensation expense
        2,102,000 2,129,000 2,228,000 2,664,000 2,979,000 4,020,000 4,802,000 5,010,000 7,585,000 5,345,000 4,731,000 5,215,000 4,507,000 5,364,000 5,881,000 6,618,000 11,431,000 7,657,000 10,012,000 13,526,000 12,204,000 5,673,000 5,846,000 5,417,000 6,220,000 6,336,000 6,559,000 6,493,000 7,855,000 6,347,000 6,699,000 7,024,000 6,528,000 8,077,000 4,467,000 5,016,000 5,804,000 -13,082,119 3,690,000 5,199,000 4,210,000 
          depreciation
        483,000 805,000 721,000 1,834,000 1,917,000 1,381,000 1,599,000 1,420,000 1,409,000 1,466,000 1,514,000 1,540,000 1,544,000 1,577,000 1,604,000 1,598,000 1,558,000 1,511,000 1,190,000 1,189,000 1,163,000 1,183,000 1,107,000 871,000 798,000 782,000 727,000 693,000 628,000 880,000 839,000 784,000 751,000 717,000 684,000 651,000 631,000 -712,798 281,000 246,000 187,000 
          net amortization of premiums and discounts on marketable securities
           -257,000 -583,000 -869,000 -1,326,000 -1,880,000 -1,716,000 -2,103,000                                
          other non-cash items
        111,000 -59,000 -882,000 492,000     -780,000 -693,000 -498,000 -283,000 -177,000 234,000 325,000 422,000 509,000 401,000 389,000 4,000 -74,000 -215,000 -501,000 -468,000 -778,000 -1,181,000 -1,139,000 -1,031,000 -668,000 -430,000 -283,000 -193,000 107,000 69,000     
          impairment of held for sale assets
         34,000 3,724,000                                     
          interest related to sale of future revenues
        1,072,000 -464,000 2,399,000 2,091,000 2,145,000                                     
          changes in operating assets and liabilities:
                                                 
          accounts receivable
        12,584,000 -7,046,000 -7,542,000 -78,000 15,756,000 -16,140,000 118,000 1,000 9,942,000 -7,765,000 -136,000 -2,044,000 4,903,000 -5,025,000 593,000 659,000 -1,105,000 -16,000 80,000 341,000 5,376,000 -4,993,000 810,000 -33,000 -1,414,000 -107,000 -299,000 -12,000 30,000 13,000 319,000 569,000 -252,000 16,000 125,000 125,000 -857,000 103,931 73,000 -87,000 -89,000 
          prepaid expenses and other current assets
        248,000 887,000 593,000 -488,000 70,000 2,789,000 1,072,000 2,142,000 -1,607,000 -968,000 160,000 -947,000 1,558,000 -444,000 1,215,000 -809,000 -99,000 2,317,000 -4,107,000 903,000 4,618,000 -462,000 -927,000 -1,259,000 -1,995,000 -758,000 -38,000 -488,000 789,000 -1,061,000 -935,000 -653,000 -761,000 -338,000 228,000 -972,000 486,000 1,666,014 -80,000 -499,000 -1,088,000 
          right-of-use assets
        709,000 1,462,000 1,428,000 2,569,000 6,125,000 3,174,000 1,223,000 -5,508,000 2,237,000 -1,744,000 2,875,000 1,533,000 7,304,000 -21,116,000 -1,866,000 2,791,000 2,716,000 2,611,000 2,513,000 8,744,000 -4,177,000 1,270,000 2,171,000 -1,547,000 1,739,000                 
          other non-current assets
         14,000 1,000 1,025,000 60,000 2,863,000 1,342,000 -899,000 -2,833,000   -1,500,000 2,277,000 -214,000 -505,000 -31,000 -92,000 -1,985,000 -825,000 13,000 93,000 -1,000      2,000 -2,232,754 11,000 -24,000 2,248,000 
          accounts payable
        1,727,000 -558,000 -3,561,000 1,258,000 -27,000 -6,999,000 -1,254,000 7,423,000 -1,456,000 -2,594,000 2,358,000 -699,000 -557,000 2,694,000 422,000 1,481,000 -229,000 1,839,000 -1,160,000 -3,835,000 2,017,000 1,302,000 -1,473,000 -3,741,000 4,767,000 -731,000 2,464,000 -2,085,000 626,000 113,000 683,000 -4,111,000 5,095,000 -4,078,000 -803,000 -6,712,000 10,078,000 -2,091,749 -2,164,000 3,715,000 544,000 
          accrued expenses
        -11,362,000 -14,912,000 -543,000 578,000 1,693,000 17,146,000 1,015,000 -3,844,000 -2,694,000 4,092,000 2,382,000 -3,787,000 1,427,000 10,990,000 -887,000 4,384,000 -3,982,000 5,273,000 -3,423,000 3,547,000 -9,563,000 4,098,000 10,048,000 1,205,000 -13,644,000 13,976,000 136,000 2,296,000 -6,923,000 1,698,000 312,000 3,284,000 -1,252,000 628,000 -2,762,000 4,339,000 -10,539,000 -4,022,159 1,900,000 320,000 1,814,000 
          accrued interest on sale of future revenues
        -5,000,000 -2,128,000                                     
          deferred revenue
         -9,695,000 -2,000,000 -4,221,000         2,183,000 -5,516,000 -11,334,000 -5,666,000 -151,000 -5,555,000 -5,768,000 -78,651,000 -3,066,000 -4,309,000 58,323,000 -3,549,000 2,682,000 -2,061,000 18,501,000 511,000 7,019,000 -3,142,000 -3,127,000 -3,103,000 -2,277,000 90,214,000 -478,065 158,000 163,000 158,000 
          operating lease liabilities
        -805,000 -1,550,000 -1,483,000 -5,149,000 -3,899,000 -3,456,000 -210,000 4,558,000 -2,396,000 1,925,000 -2,575,000 48,000 -6,808,000 22,646,000 1,043,000 -2,906,000 -3,215,000 -3,298,000 -1,564,000 -8,382,000 2,750,000 -575,000 -2,093,000 1,624,000 -1,902,000                 
          other non-current liabilities
        52,000 -1,814,000 95,000 -1,310,000 3,221,000  -488,000                                   
          net cash from operating activities
        -23,061,000 -36,387,000 -30,843,000 -50,212,000 -47,799,000 -50,762,000 -52,588,000 -57,062,000 -49,872,000 -22,240,000 -35,459,000 -38,711,000 -35,768,000 -42,273,000 -48,004,000 -37,845,000 -49,227,000 -34,582,000 -40,785,000 -38,957,000 -49,479,000 -40,100,000 -54,801,000 -30,856,000 -54,086,000 41,024,000 -26,884,000 -25,806,000 -29,003,000 1,327,000 -7,841,000 -16,733,000 -22,460,000 -25,069,000 -27,977,000 -26,162,000 69,791,000 36,519,074 -17,041,000 -9,899,000 -9,629,000 
          capital expenditures
        -92,000 -60,000 -433,000 -114,000 -540,000 -2,921,000 -3,494,000 -1,871,000 -1,307,000 -239,000 -1,333,000 -1,840,000 -624,000 -614,000 -632,000 -2,248,000 -2,845,000 -2,344,000 -2,704,000 -84,000 -1,376,000 -1,793,000 -1,841,000 -2,152,000 -1,691,000 -2,245,000 -1,513,000 -718,000 -1,415,000 -938,000 -1,390,000 -1,011,000 -289,000 -752,000 -362,000 -656,000 2,813,507 -713,000 -1,161,000 -943,000 
          free cash flows
        -23,153,000 -36,447,000 -31,276,000 -50,212,000 -47,913,000 -51,302,000 -55,509,000 -60,556,000 -51,743,000 -23,547,000 -35,698,000 -40,044,000 -37,608,000 -42,897,000 -48,618,000 -38,477,000 -51,475,000 -37,427,000 -43,129,000 -41,661,000 -49,563,000 -41,476,000 -56,594,000 -32,697,000 -56,238,000 39,333,000 -29,129,000 -27,319,000 -29,721,000 -88,000 -8,779,000 -18,123,000 -23,471,000 -25,358,000 -28,729,000 -26,524,000 69,135,000 39,332,581 -17,754,000 -11,060,000 -10,572,000 
          cash flow from investing activities
                                                 
          purchases of property and equipment
        -92,000 -60,000 -433,000 -114,000 -540,000 -2,921,000 -3,494,000 -1,871,000 -1,307,000 -239,000 -1,333,000 -1,840,000 -624,000 -614,000 -632,000 -2,248,000 -2,845,000 -2,344,000 -2,704,000 -84,000 -1,376,000 -1,793,000 -1,841,000 -2,152,000 -1,691,000 -2,245,000 -1,513,000 -718,000 -1,415,000 -938,000 -1,390,000 -1,011,000 -289,000 -752,000 -362,000 -656,000 2,813,507 -713,000 -1,161,000 -943,000 
          proceeds from the sale of equipment
        156,000 118,000                 -9,000 7,000   66,000 36,000 19,000 13,000 5,000        
          proceeds from maturities of marketable securities
         40,006,000 42,499,000 56,501,000 31,494,000 86,900,000 55,445,000 83,350,000 102,900,000 49,000,000 41,700,000 65,905,000 78,500,000 116,104,000 119,750,000 119,000,000 84,326,000 73,126,000 74,200,000 130,750,000 30,500,000 83,500,000 76,000,000 115,000,000 46,500,000 78,500,000 109,500,000 126,000,000 101,000,000 114,000,000 101,500,000 94,500,000 104,000,000        
          net cash from investing activities
        64,000 58,000 39,573,000 42,650,000 56,387,000 30,958,000 83,979,000 51,954,000 -4,745,000 62,840,000 -102,820,000 12,982,000 23,267,000 -27,528,000 89,227,000 -4,002,000 56,371,000 -22,840,000 -39,661,000 4,791,000 3,244,000 -108,894,000 -152,265,000 74,173,000 46,464,000 7,818,000 -122,302,000 76,110,000 50,626,000 -8,604,000 -13,622,000 -71,681,000 40,820,000 26,678,000 -28,847,000 -180,985,000 -656,000 4,430,908 -713,000 -1,161,000 -2,562,000 
          cash flow from financing activities
                                                 
          repayment on sale of future revenues
         -2,872,000                                     
          proceeds from issuance of common stock from at-the-market equity offering
         17,081,000                                        
          net cash from financing activities
         17,326,000 17,169,000 7,412,000 -1,437,000 55,513,000 322,000 192,000 514,000   619,000 80,000 367,000 218,000 1,057,000 2,496,000 17,082,000 261,471,000 9,100,000 822,000 211,153,000 3,047,000 84,569,000 43,353,000 2,369,000 1,533,000 30,352,000 1,240,000 2,667,000 52,681,000 58,479,000 -730,000 -309,000 97,094,000 -97,601,839 -22,000 -494,000 98,215,000 
          net increase in cash, cash equivalents, and restricted cash
        -22,997,000 -19,003,000 25,899,000 -150,000 7,151,000     41,114,000 -138,279,000 91,796,000 -12,501,000 -69,182,000 41,303,000 -41,480,000 7,362,000 -56,365,000 -77,950,000 -17,084,000 215,236,000 -139,894,000 -206,244,000 254,470,000 -4,575,000                 
          cash, cash equivalents, and restricted cash, beginning of period
        149,315,000 135,418,000 127,529,000 145,399,000 207,396,000 143,559,000 239,802,000                 
          cash, cash equivalents, and restricted cash, end of period
        126,318,000 -19,003,000 25,899,000 -150,000 142,569,000 35,709,000 31,391,000 -4,786,000 73,104,000 41,114,000 -138,279,000 91,796,000 132,898,000 -69,182,000 41,303,000 -41,480,000 214,758,000 -56,365,000 -77,950,000 -17,084,000 358,795,000 -139,894,000 -206,244,000 254,470,000 235,227,000                 
          cash and cash equivalents, end of period
        123,648,000 -19,003,000 27,106,000 -150,000 138,692,000 35,709,000 31,391,000 -4,786,000 69,227,000                          -57,554,000 -207,456,000 351,552,000 -199,688,677 -17,776,000 -11,554,000 229,204,000 
          restricted cash1
        2,670,000 -1,207,000 3,877,000 3,877,000                                 
          1 as of march 31, 2026 and march 31, 2025, restricted cash of 2,670 and 3,877 was included in restricted cash and other non-current assets on the condensed consolidated balance sheet, respectively.
                                                 
          supplemental disclosure of cash and non-cash activities:
                                                 
          loss on disposal of fixed assets
           10,000     1,583,000                             
          net accretion of discounts on marketable securities
                                                
          purchases of marketable securities
             4,000 3,000 -86,224,000 -38,753,000 -151,581,000 -27,385,000 -40,798,000 -105,404,000 -26,263,000 -123,138,000 -60,381,000 -104,321,000 -110,443,000 -66,705,000 -127,422,000 -158,041,000 -233,979,000 -66,384,000 -37,057,000 -198,557,000 -31,877,000 -74,692,000 -108,208,000 -126,697,000 -171,791,000 -52,674,000 -77,033,000 -117,610,000       
          proceeds from sale of future revenues
                                                 
          proceeds from exercise of stock options
         49,000    1,000 192,000 30,000   7,000 80,000 218,000 430,000 2,496,000 16,567,000 12,002,000 8,668,000 947,000 6,839,000 3,047,000 9,107,000 2,137,000 2,086,000 1,533,000 1,952,000 1,451,000 2,515,000 4,410,000 1,220,000 45,000 55,000 435,000     
          issuance of common stock under benefit plans
                     612,000   626,000   545,000                   
          proceeds from issuance of common stock under employee stock purchase plan
                                              
          proceeds from issuance of common stock from at the market equity offering
           7,184,000 1,435,000                                     
          1 as of march 31, 2025 and march 31, 2024, restricted cash of 3,877 and 3,877 was included in restricted cash and other non-current assets on the consolidated balance sheet, respectively.
                                                 
          net income
                                                 
          adjustments to reconcile net income to net cash from operating activities:
                                                 
          non-cash interest expense on liability for sale of future revenues
                                                 
          other current and non-current liabilities
                1,673,000             -3,136,000 -891,000 511,000 833,000 1,124,000 525,000 -878,000 881,000     8,000        
          proceeds from offering of common stock, net of issuance costs
                       1,000 -11,000 249,469,000 -113,000 -125,000   75,125,000    28,318,000 -3,000 48,474,000         
          1as of december 31, 2024, december 31, 2023, and december 31, 2022 restricted cash of 3,877, 3,877, and 3,877, respectively, was included in restricted cash and other non-current assets on the consolidated balance sheet
                                                 
          net decrease in cash, cash equivalents, and restricted cash
                -54,425,000                                 
          1 as of september 30, 2024, restricted cash of 3,877 was included in restricted cash and other non-current assets on the consolidated balance sheet
                                                 
          1 as of september 30, 2023, restricted cash of 3,878 was included in restricted cash and other non-current assets on the consolidated balance sheet
                                                 
          1 as of june 30, 2024, restricted cash of 3,877 was included in restricted cash and other non-current assets on the consolidated balance sheet
                                                 
          1 as of june 30, 2023, restricted cash of 3,877 was included in restricted cash and other non-current assets on the consolidated balance sheet
                                                 
          1 first quarter 2024 restricted cash of 3,877 was included in restricted cash and other non-current assets on the consolidated balance sheet
                                                 
          1 first quarter of 2023 restricted cash of 3,877 was included in restricted cash and other non-current assets on the consolidated balance sheet
                                                 
          fixed asset additions included in accounts payable and accrued expenses
                1,644,000 646,000 -13,000 -158,000 370,000 1,027,000 286,000 -72,000 199,000 152,000 -482,000 612,000 467,000 -254,000 481,000 -276,000 705,000 -44,000 676,000 -260,000 356,000 -17,000 305,000 242,000 129,000 389,000 143,000 84,000 7,000 -243,870 -20,000 -262,000 526,000 
          cash paid in connection with operating lease liabilities
                 3,325,000 3,365,000 1,841,000 3,897,000 2,957,000 4,805,000 3,343,000 3,746,000 4,176,000 2,187,000 2,483,000 4,248,000 2,003,000 2,632,000 2,587,000 2,538,000 1,366,000 1,515,000 1,365,000 1,724,000             
          right-of-use assets obtained in exchange of operating lease obligations
                 1,683,000   25,153,000    983,000       19,461,000             
          offering expenses included in accounts payable and accrued expenses
                                                 
          remeasurement of operating lease liabilities and right-of-use assets due to lease modification
                    -3,781,000                             
          realized gain on corporate equity securities
                                                 
          non-cash research and development expenses
                                           5,000,000     
          proceeds from sale of corporate equity securities
                                                 
          issuance of common stock for settlement of success payments
                            27,500,000          9,530,000         
          offering costs included in accounts payable and accrued expenses
                            10,000  -124,000        3,000 19,000         
          unrealized gain on corporate equity securities
                              1,416,000 -7,192,000 -7,333,000                 
          non-cash investment in equity securities
                                               
          payments on construction financing lease obligation
                                     -236,000 -211,000 -207,000 -203,000 -199,000 -175,000 53,000 -443,000     
          reclassification of liability for common stock subject to repurchase
                                     1,000 3,000 2,000 3,000 3,000 3,000 -7,989 2,000 3,000 3,000 
          issuance of common stock for repayment of notes payable
                                                 
          issuance of common stock for asset acquisition
                                               
          receivable of proceeds from offering of common stock
                                                 
          issuances of common stock under benefit plans
                                 337,000   318,000           
          payments of notes payable
                                                
          non-cash research and development expense
                                      12,500,000 1,942,000         
          right-of-use asset
                                  -204,000 1,003,000 981,000             
          operating lease liability
                                  218,000 -946,000 -1,379,000             
          net decrease in cash and cash equivalents
                                      -20,223,000           
          cash, cash equivalents and restricted cash, beginning of period
                                  136,395,000  148,249,000         
          cash, cash equivalents and restricted cash, end of period
                                  -105,833,000 52,673,000 159,551,000  -20,223,000 -85,747,000 219,290,000         
          issuance of common stock for settlement of notes payable
                                               
          adjustment to deferred revenue for revenue adoption
                                        474,000         
          net increase in cash and cash equivalents
                                   52,673,000 23,156,000    71,041,000  -57,554,000 -207,456,000 166,229,000 -56,651,857 -17,776,000 -11,554,000 86,024,000 
          receivable of proceeds from exercise of stock options
                                                 
          issuance of common stock for settlement of liabilities
                                                 
          re-measurement of warrant to purchase redeemable securities
                                               87,000 
          accretion of redeemable convertible preferred stock to redemption value
                                             -46,953 47,000 
          reclassification of warrants to additional paid in capital
                                                 
          conversion of preferred stock to common stock upon closing of the initial public offering
                                             -199,715,038 199,915,000 
          payments of notes payables
                                                 
          change in fair value of preferred stock tranche asset or liability
                                                 
          changes in fair value of anti-dilutive protection liability
                                                 
          proceeds from equipment loan, net of issuance costs
                                                 
          proceeds from the issuance of redeemable convertible preferred stock and tranche rights, net of issuance costs
                                                 
          payments of equipment loan principal
                                                 
          payments of final fee for loan payoff
                                                 
          proceeds from the issuance of common stock and restricted stock
                                                 
          payments of initial public offering costs
                                                 
          construction financing lease obligation
                                                 
          conversion of anti-dilutive protection liability to common stock
                                                 
          interest paid
                                                 
          reclassification of preferred stock tranche liability upon settlement
                                                 
          changes in restricted cash
                                             1,617,381 -1,619,000 
          proceeds from public offering of common stock, net of issuance costs
                                          -417,000 97,102,000     
          cash and cash equivalents, beginning of period
                                          185,323,000 -143,036,820 143,180,000 
          offering costs incurred but unpaid at period end
                                            397,000     
          changes in fair value of warrant liability
                                             -86,913    
          interest related to facility lease obligation
                                                 
          changes in deferred rent
                                             -264,690 110,000 110,000 45,000 
          proceeds from initial public offering of common stock, net of issuance costs
                                             -97,390,512 -196,000 -498,000 98,182,000 
          accrual of final payment fee on equipment loan and debt discount
                                                 
          initial public offering costs incurred but unpaid at period end
                                               -301,000 497,000 
          non-cash interest expense
                                                 
          proceeds from stock option exercises
                                              174,000 4,000 33,000 
          capitalization of construction-in-progress related to facility lease obligation
                                              9,919,000 11,027,000 11,649,000 
          reclassification of warrants to additional paid-in capital
                                              376,000 
          non-cash loss on debt extinguishment
                                                 
          cash paid for interest