7Baggers
Quarterly
Annual
    Unit: USD2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 2014-06-30 2014-03-31 2013-12-31 2013-09-30 2013-06-30 2013-03-31 2012-12-31 2012-09-30 2012-06-30 2012-03-31 2011-12-31 2011-09-30 2011-06-30 2011-03-31 2010-12-31 2010-09-30 2010-06-30 2010-03-31 2009-12-31 2009-09-30 2009-06-30 2009-03-31 2008-12-31 2008-09-30 2008-06-30 2008-03-31 2007-12-31 2007-09-30 2007-06-30 2007-03-31 2006-12-31 2006-09-30 2006-06-30 2006-03-31 2005-12-31 2005-09-30 2005-06-30 2005-03-31 2004-12-31 2004-09-30 
      
    		                                                                                     
      operating activities
    		                                                                                     
      net income
    		26,927,000 18,721,000 -96,099,000 7,050,000 17,594,000 11,386,000 -8,721,000 219,000 14,293,000 3,431,000 -24,332,000 67,733,000 63,809,000 128,755,000 32,859,000 99,779,000 -28,430,000 4,473,000 891,000 -15,467,000 4,401,000 -51,579,000 -12,595,000 -36,756,000 -33,459,000 -42,713,000 -39,672,000 -39,969,000 -40,528,000 -39,444,000 -38,958,000 -27,421,000 -22,128,000 -20,318,000 -25,287,000 -21,741,000 -34,694,000 -28,986,000 -27,023,000 -26,862,000 -30,124,000 -23,591,000 -26,217,000 -22,286,000 -29,819,000 -24,777,000 -13,840,000 -13,056,000 -15,675,000 -17,164,000 -20,825,000 -20,543,000 -17,791,000 -15,110,000 -16,505,000  -15,229,000 -10,635,000 -18,466,000         3,099,000 -5,420,000 -6,079,000 -12,429,000 -12,076,000 -17,101,000 -17,704,000 -13,090,000 -16,455,000 -12,152,000 -15,273,000 -8,172,000 -8,762,000 -8,284,000 -8,579,000 5,070,000 -5,163,000 -4,033,000 
      adjustments to reconcile net income to net cash from operating activities:
    		                                                                                     
      depreciation and amortization
    		1,291,000 1,242,000 1,173,000 1,184,000 1,184,000 1,135,000 1,124,000 1,114,000 1,115,000 1,100,000 1,013,000 837,000 890,000 1,100,000 985,000 1,016,000 1,078,000 1,096,000 1,106,000 1,107,000 1,103,000 1,049,000 1,014,000 1,100,000 4,642,000 1,494,000 1,702,000 1,110,000 853,000 835,000 823,000 788,000 782,000 885,000 789,000 683,000 628,000 544,000 402,000 407,000 324,000 299,000 335,000 388,000 336,000 341,000 339,000 341,000 340,000 327,000 319,000 309,000 306,000 300,000 292,000 294,000 305,000 344,000 360,000 301,000 343,000 372,000 399,000 422,000 475,000 490,000 470,000 489,000 453,000 470,000 438,000 392,000 379,000 371,000 341,000 333,000 1,624,000 -1,011,000 184,000 181,000 191,000 203,000 184,000 229,000 97,000 
      amortization of right-of-use assets
    		803,000 797,000 863,000 887,000 870,000 844,000 824,000         702,000 687,000 673,000 653,000 656,000 645,000 627,000 634,000 633,000 696,000 744,000 1,302,000                                                           
      inventory write off
    		-338,000 0 3,976,000  0 0 1,264,000                                                                               
      sublease termination loss
    		   49,000 0 0 4,765,000                                                                               
      accretion of discounts on marketable securities
    		-1,199,000 -1,698,000 -2,137,000  -3,427,000 -3,937,000 -4,528,000  -4,050,000 -3,765,000 -3,498,000           9,000 -87,000  -418,000 -552,000 -323,000  -465,000 -505,000 -176,000                                                       
      stock-based compensation expense
    		12,390,000 12,979,000 14,455,000 13,004,000 13,083,000 13,518,000 13,014,000 11,309,000 10,687,000 10,562,000 10,034,000                                  1,586,000 1,676,000 1,270,000      1,903,000 2,069,000 2,322,000  1,287,000 1,167,000 1,480,000  586,000 425,000 541,000 933,000 916,000 667,000 519,000 717,000 1,052,000 775,000 661,000 1,049,000 985,000 689,000 808,000 917,000 970,000         
      bad debt expense
    		0 0 10,970,000     0 0 0 12,313,000                                                                           
      non-cash interest expense
    		-2,513,000 1,642,000 1,691,000 -1,116,000 1,698,000 -1,121,000 1,695,000 -1,126,000 1,690,000 -1,130,000 1,686,000 -1,134,000 1,682,000 -1,140,000 1,680,000 -938,000   414,000 413,000 403,000 388,000 1,338,000 1,440,000 1,398,000 1,321,000 814,000 811,000 805,000 791,000 348,000                                                       
      loss on debt extinguishment
    		0 0 82,095,000             0 0                                                                     
      changes in operating assets and liabilities:
    		                                                                                     
      accounts and other receivables
    		24,000 -16,788,000 -9,651,000 28,371,000 -12,647,000 -16,476,000 -1,621,000 2,333,000 -1,513,000 12,112,000 30,336,000 -16,397,000 43,124,000 -37,306,000 -5,120,000 68,546,000 -94,462,000 -21,906,000 -61,333,000 8,362,000 -30,120,000 7,232,000 751,000 -64,000 -1,240,000 -1,791,000 -2,087,000 -2,197,000 -203,000 -541,000 91,000 -71,000 27,000 655,000 -123,000 948,000 -426,000                                                 
      inventories
    		2,737,000 -1,284,000 -8,325,000 -9,533,000 60,000 -656,000 -9,780,000 -5,526,000 3,077,000 4,605,000 1,753,000 23,360,000 -43,115,000 5,059,000 -17,703,000 3,374,000 19,154,000 -17,605,000 -5,157,000 -4,656,000 -4,641,000 -6,293,000 -6,767,000 -1,976,000 -2,727,000 -9,060,000 -8,547,000 -6,570,000 -7,340,000 -4,562,000 -238,000                                                       
      prepaid manufacturing
    		           12,727,000 41,750,000 83,853,000 21,325,000 -49,892,000 -73,465,000 -3,656,000 -3,219,000                                                                   
      prepaid expenses and other current assets
    		3,335,000 -77,000 -5,518,000 -467,000 3,647,000 -1,490,000 -4,800,000 -23,000 -1,478,000 -1,868,000 -1,304,000 14,375,000 34,534,000 -51,543,000 -9,231,000 -12,671,000 -51,640,000 -76,000 -171,000 9,580,000 -9,323,000 -1,083,000 -1,000,000 -1,669,000 1,034,000 -797,000 154,000 -1,498,000 -721,000 -580,000 394,000 11,000 -199,000 -1,603,000 -39,000 -244,000 600,000 505,000 -301,000 62,000 1,369,000 -380,000 580,000 -480,000 1,400,000 -2,655,000 -948,000 -255,000 121,000 -24,000 835,000 367,000 1,726,000 -2,277,000 -738,000 263,000 395,000 -273,000 -155,000 -281,000 -262,000 -15,000 -216,000 422,000 223,000 -133,000 -107,000 360,000 262,000 67,000 844,000 -111,000 -653,000 -78,000 -1,009,000 444,000 158,000 1,429,000 -1,427,000  330,000 -19,000 -721,000  -113,000 
      other assets
    		   -312,000 -777,000 -219,000 118,000 -160,000 27,000 26,000 677,000 26,000 26,000 84,000 -49,000 225,000 215,000 -170,000 -95,000 -335,000 -57,000 120,000 43,000 165,000 -1,710,000 1,305,000 1,872,000 -1,142,000 -1,730,000 -837,000 3,000  -1,017,000                                   6,000 26,000 -31,000 -80,000 -96,000 210,000 -2,000 1,157,000 -6,000 -2,000    0 -412,000 402,000  4,000 
      accounts payable
    		1,355,000 -1,835,000 -4,668,000 1,876,000 2,592,000 2,071,000 -2,640,000 2,564,000 -461,000 -4,247,000 4,096,000 390,000 -2,018,000 -14,619,000 16,938,000 -222,000 -7,754,000 7,504,000 -295,000 -2,015,000 2,560,000 -1,898,000 -2,095,000 1,813,000 218,000 -1,607,000 4,424,000 1,040,000 754,000 1,274,000 349,000 -416,000 1,435,000 -824,000 -2,110,000 477,000 -900,000 946,000 658,000 973,000 -375,000 -1,395,000 2,043,000 -3,807,000 3,172,000 -42,000 154,000 220,000 36,000 -474,000 -439,000 588,000 423,000 -1,203,000 318,000 727,000 -429,000 -138,000 -449,000 262,000 1,034,000 -58,000 -595,000 649,000 -185,000 134,000 183,000 -225,000 -249,000 -1,385,000 -1,654,000 2,467,000 -1,454,000 1,841,000 -617,000 -927,000 1,691,000 248,000 -6,000  639,000 891,000 -662,000  -102,000 
      lease liabilities
    		-999,000 -1,051,000 -1,101,000 -1,167,000 -1,111,000 -1,084,000 -1,025,000 -994,000 -956,000 -886,000 -793,000 -759,000 -688,000 -872,000 -806,000 -818,000 -862,000 -803,000 -751,000 -741,000 -748,000 -711,000 -672,000 -660,000 -579,000 -655,000 -106,000                                                           
      accrued and other liabilities
    		-9,984,000 10,783,000 -7,363,000 7,065,000 3,594,000 6,742,000 -6,368,000                                                                               
      net cash from operating activities
    		33,829,000 23,431,000 -19,639,000 53,011,000 19,467,000 10,713,000 -16,679,000 13,766,000 31,129,000 28,046,000 27,622,000 34,948,000 61,560,000 16,651,000 -50,443,000 120,497,000 66,211,000 110,788,000 38,032,000 -15,743,000 -27,821,000 -21,821,000 -26,866,000 -23,012,000 -21,977,000 -36,361,000 -39,902,000 -33,630,000 -33,872,000 -33,927,000 -29,872,000 -17,749,000 -17,127,000 -17,392,000 -25,250,000 -26,282,000 -28,208,000 -25,427,000 -27,134,000 -21,846,000 -23,002,000 -23,572,000 -24,139,000 -16,867,000 -23,089,000 -22,606,000 -11,176,000 -11,843,000 -12,255,000 -15,689,000 -18,886,000 -7,592,000 -12,347,000 -15,689,000 -8,181,000 -5,288,000 -12,704,000 -9,629,000 -19,495,000 -17,886,000 -12,189,000 -13,793,000 -7,502,000 -9,291,000 -8,842,000 -7,372,000 -8,047,000 3,981,000 1,974,000 -8,725,000 -14,265,000 18,429,000 -17,104,000 -18,458,000 -14,899,000 -17,681,000 -1,644,000 -10,381,000 -7,534,000 -8,495,000 -7,614,000 1,307,000 -8,056,000 -5,306,000 -999,000 
      capex
    		-832,000 -1,798,000 -1,882,000 -2,517,000 -1,158,000 -560,000 -394,000 -2,128,000 -183,000 -1,137,000 -357,000 -1,545,000 -1,522,000 -3,706,000 649,000 -4,006,000 -4,199,000 655,000 -1,336,000 -772,000 -25,000 -970,000 -1,944,000 -2,268,000 -12,972,000 -7,501,000 -3,882,000 -1,349,000 -1,199,000 -742,000 -897,000 -295,000 -132,000 -8,000 -234,000 -1,241,000 -1,600,000 -2,305,000 -2,611,000 -2,724,000 -2,578,000 -1,050,000 -618,000 0 -288,000 -521,000 -398,000 -313,000 -488,000 -293,000 -535,000 -1,204,000 -324,000 -471,000 -932,000 -564,000 -159,000 -278,000 -141,000 -287,000 -94,000 -433,000 394,000 71,000 -378,000 -505,000 435,000 230,000 444,000 -1,374,000 -3,398,000 0 0 0 -711,000 -647,000 0 0 -39,000 -110,000 -89,000 -282,000 -81,000 -209,000 -1,190,000 
      free cash flows
    		32,997,000 21,633,000 -21,521,000 50,494,000 18,309,000 10,153,000 -17,073,000 11,638,000 30,946,000 26,909,000 27,265,000 33,403,000 60,038,000 12,945,000 -49,794,000 116,491,000 62,012,000 111,443,000 36,696,000 -16,515,000 -27,846,000 -22,791,000 -28,810,000 -25,280,000 -34,949,000 -43,862,000 -43,784,000 -34,979,000 -35,071,000 -34,669,000 -30,769,000 -18,044,000 -17,259,000 -17,400,000 -25,484,000 -27,523,000 -29,808,000 -27,732,000 -29,745,000 -24,570,000 -25,580,000 -24,622,000 -24,757,000 -16,867,000 -23,377,000 -23,127,000 -11,574,000 -12,156,000 -12,743,000 -15,982,000 -19,421,000 -8,796,000 -12,671,000 -16,160,000 -9,113,000 -5,852,000 -12,863,000 -9,907,000 -19,636,000 -18,173,000 -12,283,000 -14,226,000 -7,108,000 -9,220,000 -9,220,000 -7,877,000 -7,612,000 4,211,000 2,418,000 -10,099,000 -17,663,000 18,429,000 -17,104,000 -18,458,000 -15,610,000 -18,328,000 -1,644,000 -10,381,000 -7,573,000 -8,605,000 -7,703,000 1,025,000 -8,137,000 -5,515,000 -2,189,000 
      investing activities
    		                                                                                     
      purchases of marketable securities
    		-139,862,000 -18,096,000 -93,697,000 -33,016,000 -164,926,000 -175,436,000 -150,685,000 -152,881,000 -224,509,000 -74,230,000 -185,301,000 -117,630,000 -201,016,000 -63,285,000 -250,375,000 -1,000 1,000 -92,912,000 -72,016,000 -29,804,000 -68,800,000 -85,197,000 -17,985,000 -34,043,000 -72,807,000 -79,136,000 -29,205,000 -25,996,000 -987,000 -45,718,000 -141,103,000 -34,988,000 -99,639,000 -48,393,000 -44,652,000 -4,727,000 -23,919,000 -37,051,000 -61,057,000 -81,018,000 -109,264,000 0 -18,654,000 0 -7,556,000 -23,432,000 -13,819,000 -143,471,000 -19,046,000 -16,073,000 -13,454,000 -36,515,000 -55,234,000 -81,564,000 -32,836,000 -73,198,000 -18,498,000 -18,505,000 -1,004,000 -49,941,000 -2,537,000   0 -2,000 -2,016,000 -12,271,000 -12,673,000 -9,662,000 -7,494,000 -5,926,000 -38,753,000 -975,000 -24,414,000 -16,090,000 -46,215,000 -11,974,000 0 -7,653,000 -44,811,000 -3,491,000 -20,021,000 -15,691,000   
      proceeds from maturities and redemption of marketable securities
    		168,422,000 114,340,000 104,535,000  150,807,000 147,448,000 154,265,000                                                                               
      purchases of property and equipment
    		-1,237,000 -1,452,000 -3,928,000 -3,478,000 -1,346,000 -779,000 -749,000 -1,723,000 -347,000 -751,000 -1,283,000 -1,587,000 -1,281,000 -2,913,000 -1,358,000 -3,036,000 -3,629,000 -1,065,000 -1,747,000 -769,000 -265,000 -686,000 -2,352,000 -1,831,000 -9,187,000 -7,501,000 -3,882,000 -1,349,000 -1,199,000 -742,000 -897,000 -295,000 -132,000 -8,000 -234,000 -1,241,000 -1,600,000 -2,305,000 -2,611,000 -2,724,000 -2,578,000 -1,050,000 -618,000     -313,000 -488,000 -293,000 -535,000 -1,204,000 -324,000 -471,000 -932,000 -564,000 -159,000 -278,000 -141,000 -287,000 -94,000 -433,000 394,000 71,000 -378,000 -505,000 435,000 230,000 444,000 -1,374,000 -3,398,000    -711,000 -647,000   -39,000 -110,000 -89,000 -282,000 -81,000 -209,000 -1,190,000 
      net cash from investing activities
    		27,323,000 94,792,000 6,910,000 23,366,000 -15,465,000 -28,767,000 2,831,000 -20,242,000 -106,074,000 24,722,000 -52,334,000 -32,967,000 -119,047,000 52,502,000 -216,483,000 54,938,000 45,672,000 -63,752,000 -22,633,000 14,342,000 -2,054,000 -49,383,000 10,563,000 24,851,000 -40,219,000 -42,027,000 14,613,000 44,412,000 43,564,000 27,175,000 -59,685,000 6,057,000 -82,348,000 -25,401,000 -7,011,000 28,122,000 25,981,000 11,394,000 20,752,000 -36,552,000 -63,507,000 24,785,000 -10,522,000 37,111,000 25,862,000 12,892,000 14,732,000 -102,568,000 6,660,000 8,205,000 36,351,000 4,583,000 1,442,000 -39,375,000 -6,343,000 -48,722,000   17,000,000   -28,790,000 394,000 1,700,000 7,195,000 7,745,000 3,235,000 1,634,000 7,125,000 7,728,000 13,629,000 -20,813,000 21,592,000 -18,028,000 13,652,000 -29,248,000 7,264,000 -13,990,000 15,594,000 -35,104,000 21,282,000 -7,658,000 2,773,000 -49,846,000 -1,190,000 
      financing activities
    		                                                                                     
      proceeds from issuance of convertible notes
    		0 0 39,708,000             0 0                                                                     
      payment for debt issuance costs
    		0 -562,000 -3,938,000                                                                                   
      payments for debt extinguishment
    		0 0 -80,938,000                                                                                   
      proceeds from unwind of capped call options
    		0 0 46,554,000                                                                                   
      payments for repurchase of common stock
    		-572,000 -71,170,000 -29,465,000                                                                                   
      proceeds from exercise of stock options
    		95,000 235,000 6,503,000  1,871,000 419,000 1,635,000                                              446,000 272,000 1,071,000   0 65,000  28,000 40,000 3,000 9,000 0   0 0 0 5,000  0 0 22,000           
      proceeds from employee stock purchase plan
    		664,000 0 835,000 0 856,000 0 904,000 0 758,000 0 777,000 1,000 720,000 0 710,000 0 458,000 0 383,000 0 361,000 0 311,000 0 158,000 0 407,000 0 339,000 0 255,000 1,000 137,000 0 155,000 -1,000 355,000 0 261,000 0 188,000 0 103,000 0 60,000 1,000 69,000 0 77,000 0 147,000 0 179,000 0 128,000 0 92,000 0 40,000 0 30,000 0 42,000 0 35,000 0 37,000 0 68,000 0 136,000 0 78,000 0 71,000 0 57,000 0 57,000 -1,000 49,000 0 66,000   
      payments for taxes related to net share settlement of restricted and performance stock units
    		-248,000 -421,000 -11,141,000                                                                                   
      net cash from financing activities
    		-61,000 -71,918,000 -31,882,000 -98,875,000 2,476,000 -1,415,000 -4,203,000 1,776,000 2,994,000 -294,000 -3,090,000 153,000 8,057,000 1,028,000 10,287,000 14,816,000 5,322,000 3,335,000 32,303,000 66,000 1,412,000 93,482,000 14,539,000 0 65,744,000 345,000 88,262,000 6,000 359,000 -123,000 98,829,000 18,078,000 81,712,000 58,665,000 29,387,000 -216,000 387,000 24,000 336,000 300,000 153,006,000 20,514,000 139,000 9,758,000 60,000 14,000 69,000 125,290,000 76,000 20,000 15,000 -14,178,000 930,000 70,037,000 2,253,000 67,054,000 4,787,000 18,660,000 939,000 43,364,000 2,122,000 41,229,000 916,000 19,708,000 2,310,000 4,000 37,000 0 -749,000 0 2,141,000 2,000,000 3,578,000 30,000,000 74,000 45,070,000 219,000 17,554,000 57,000 33,157,000 384,000 66,000 98,000 228,000 -256,000 
      effect of exchange rate changes on cash and cash equivalents, and restricted cash
    		55,000 1,100,000 458,000 -960,000 363,000 -64,000 -201,000 479,000 -305,000 -1,000 151,000                                                                           
      net increase in cash and cash equivalents, and restricted cash
    		61,146,000                                                                                     
      cash and cash equivalents, and restricted cash at beginning of period
    		0 0 96,154,000  0 0 150,556,000  0 0 202,211,000                                                                           
      cash and cash equivalents, and restricted cash at end of period
    		61,146,000 47,405,000 52,001,000  6,841,000 -19,533,000 132,304,000  -72,256,000 52,473,000 174,560,000                                                                           
      supplemental disclosure of cash flow information
    		                                                                                     
      cash paid during the period for income taxes
    		455,000 1,737,000 413,000  1,614,000 2,014,000 949,000  703,000 678,000 32,000  279,000 422,000 87,000                                                                       
      cash paid during the period for interest
    		0 503,000 1,518,000  0    0    0    4,912,000 -2,243,000 4,296,000  4,392,000 4,345,000 3,412,000  3,415,000 3,360,000 1,940,000  1,930,000 1,900,000 813,000                                                       
      non-cash investing and financing activities:
    		                                                                                     
      purchases of property and equipment, not yet paid
    		405,000 -346,000 2,046,000 961,000 188,000 219,000 355,000 -405,000 164,000 -386,000 926,000 42,000 -241,000 -793,000 2,007,000 -970,000 -570,000 1,720,000 411,000 -3,000 240,000 -284,000 408,000 -437,000 -3,785,000                                                             
      right-of-use assets obtained in exchange of operating lease liabilities
    		        431,000 623,000 278,000                                                                           
      net decrease in cash and cash equivalents, and restricted cash
    		  -44,153,000 -23,458,000   -18,252,000    -27,651,000                                                                           
      inventory write-off
    		           19,803,000                                                                          
      amortization of premiums (accretion of discounts) on marketable securities
    		                                                                                     
      change in fair value of warrant liability
    		           0 0 0 -1,801,000 -19,222,000 45,121,000 -2,097,000 25,552,000 76,000 -21,245,000 25,655,000 -8,610,000                                                               
      gain on sale of assets
    		       0    0 0   0    0                                                                  
      cepi accrual
    		           0 368,000 0 -21,478,000                                                                       
      deferred revenue
    		           -87,395,000 -104,603,000 -121,205,000 -36,661,000 -8,724,000 229,031,000 13,005,000 78,340,000 16,500,000                                                                 -250,000 
      proceeds from maturities and redemptions of marketable securities
    		           86,250,000 83,250,000 117,700,000 35,250,000 57,975,000 48,300,000 30,225,000 51,130,000 30,915,000 43,250,000 36,500,000 37,900,000                                                               
      proceeds from sale of assets, net of transaction costs
    		           0    0    3,992,000                                                                  
      proceeds from warrants exercises
    		             0 8,455,000 13,556,000 882,000                                                                     
      proceeds from exercise of stock options and/or release of restricted stock awards
    		       2,021,000 2,722,000 1,378,000 239,000    1,122,000                                                                       
      payments for taxes related to net share settlement of rsus
    		       -245,000 -486,000 -1,672,000 -4,106,000                                                                           
      cash and cash equivalents, and restricted cash at beginning of year
    		                                                                                     
      cash and cash equivalents, and restricted cash at end of year
    		                                                                                     
      cash paid during the year for income taxes
    		                                                                                     
      cash paid during the year for interest
    		                                       0 287,000 249,000 184,000                                           
      reclassification of contract asset from other current assets to other assets
    		       0 0 0 71,307,000                                                                           
      reclassification of cepi accrual to cepi accrual long-term
    		       0 0 0 -60,337,000                                                                           
      advance payments forgiven per cepi-bio e assignment agreement
    		       0 0                                                                             
      right-of-use assets obtained in exchange for operating lease liabilities
    		                       1,522,000 4,297,000 0 34,807,000                                                           
      proceeds from sale of assets
    		                                                                                     
      payments for taxes related to net share settlement of restricted stock units
    		    -251,000 -1,834,000 -6,742,000                                                                               
      proceeds from issuances of common stock
    		                                                                                     
      purchases of capped call options
    		               0 0                                                                     
      repayment of long-term debt
    		               0 0                                                                     
      amortization of right-of-use assets and loss on disposal of property and equipment
    		        755,000 693,000 642,000  600,000 901,000 743,000                                                                       
      accrued liabilities and other liabilities
    		        8,943,000 7,413,000 -5,001,000  3,574,000 16,972,000 -39,589,000  62,330,000 10,604,000 -2,847,000  10,023,000 373,000 -3,728,000  -3,777,000 4,304,000 -7,878,000                                                           
      proceeds from maturities of marketable securities
    		        117,782,000 99,703,000 134,250,000              41,775,000 44,610,000 54,700,000 71,757,000 47,250,000 73,635,000 91,815,000 41,340,000 17,423,000 23,000,000 37,875,000 34,090,000 51,500,000 50,750,000 84,420,000 47,190,000 48,335,000 25,835,000 8,750,000 37,571,000 33,706,000 36,845,000 28,949,000 41,216,000 26,194,000 24,571,000 50,340,000 42,302,000 57,000,000 42,660,000 27,425,000 25,054,000 18,308,000 16,222,000 18,145,000 19,000,000    0 6,500,000 9,250,000 13,750,000 12,501,000 15,000,000 15,150,000 16,750,000 18,100,000 21,000,000             
      gain on disposal of property and equipment and from lease termination
    		                    0 0 -76,000                                                               
      realized gain on available-for-sale securities
    		                   -1,000                                                                  
      stock compensation expense
    		           8,727,000 8,613,000 7,929,000 7,646,000 6,162,000 5,376,000 5,024,000 4,723,000 3,516,000 4,102,000 4,088,000 1,778,000 5,189,000 4,748,000 9,349,000 6,170,000 6,343,000 6,046,000 6,290,000 4,799,000 4,073,000 3,660,000 3,363,000 3,821,000 4,096,000 3,662,000 3,124,000 3,244,000 2,814,000 2,630,000 1,918,000 1,954,000     1,493,000 2,845,000 3,736,000 4,266,000                                   
      cost of sales - amortization of intangible assets
    		                   0 0 202,000 2,298,000 2,323,000 2,324,000 2,297,000 2,273,000 2,324,000 3,823,000 2,298,000 2,417,000                                                       
      tenant improvements provided by the landlord
    		                   229,000 0 0 908,000 360,000 3,411,000                                                             
      acquisition of technology licenses
    		                   0 0 0 -7,000,000 0 0 0 -7,000,000 0 -1,500,000 0 -9,500,000                                                       
      proceeds from sales of marketable securities
    		                   10,008,000                                                0 -1,000 0 4,047,000               
      proceeds from exercise of stock options and release of restricted stock awards
    		           152,000 7,337,000                                                                         
      amortization of premium (accretion of discounts) on marketable securities
    		                73,000 148,000 221,000                                                                   
      long-term deferred revenue
    		                -38,981,000                                                                     
      proceeds from issuance of common stock
    		                0 0 28,156,000  840,000 93,468,000 14,229,000  51,999,000 326,000 13,623,000      80,987,000 58,665,000 29,535,000      163,686,000                                             
      proceeds from warrants exercised
    		                                                                                     
      effect of exchange rate changes on cash, cash equivalents and restricted cash
    		            -1,098,000 -523,000 -134,000 -418,000 -467,000 185,000 -731,000 731,000 675,000 313,000 -225,000 345,000 -485,000 148,000 -192,000 -155,000 -67,000 -477,000 217,000                                                       
      net increase in cash, cash equivalents and restricted cash
    		            -50,528,000 69,658,000 -256,773,000 189,833,000 116,738,000 50,556,000 46,971,000   22,591,000 -1,989,000 2,184,000 3,063,000 -77,895,000 62,781,000 10,633,000 9,984,000 -7,352,000 9,489,000                                                       
      cash, cash equivalents and restricted cash at beginning of period
    		            0 0 436,408,000  0 0 32,310,000  0 0 40,100,000  0 0 49,967,000  0 0 27,213,000                                                       
      cash, cash equivalents and restricted cash at end of period
    		            -50,528,000 69,658,000 179,635,000  116,738,000 50,556,000 79,281,000  -27,788,000 22,591,000 38,111,000  3,063,000 -77,895,000 112,748,000  9,984,000 -7,352,000 36,702,000                                                       
      right-of-use assets obtained in exchange of lease liabilities
    		            708,000 594,000 1,173,000                                                                       
      remeasurement of operating lease right-of-use assets for lease modification
    		                                                                                     
      (accretion of discounts) amortization of premium on marketable securities
    		             -317,000 -181,000                                                                       
      proceeds from long-term debt
    		                       0 0 0 74,250,000 0 0 0 99,000,000                                                       
      proceeds from issuances of preferred stock
    		                                                                                     
      proceeds from exercise of stock options and restricted stock awards
    		               1,260,000 3,982,000    211,000                32,000 24,000 75,000 294,000 128,000 99,000 10,000 36,000 0   82,000 0 20,000 10,000                                   
      cash, cash equivalents and restricted cash at beginning of year
    		                                                                                     
      cash, cash equivalents and restricted cash at end of year
    		                                                                                     
      proceeds allocated to warrant liability at issuance
    		                       0                                                              
      interest expense
    		                                                                                     
      proceeds from exercise of warrants
    		                  3,377,000                     6,000 -6,000 202,000 26,000          300,000 151,000 1,054,000  0                             
      proceeds (tax withholding) from exercise of stock options and restricted stock awards
    		                  387,000     0 1,000                                                             
      (gain) loss on disposal of property and equipment and from lease termination
    		                                                                                     
      non-cash acquisition of technology license
    		                           0 0 0 12,773,000                                                       
      proceeds from issuance of preferred stock
    		                                                                                     
      net decrease in cash, cash equivalents and restricted cash
    		                                                                                     
      (tax withholding) from exercise of stock options and restricted stock awards
    		                      -1,000                                                               
      gain on disposal of property and equipment
    		                                -8,000 -3,000 -21,000          0 -4,000 -20,000 14,000 0                            0 0 -50,000       
      accretion of discounts and amortization of premiums on marketable securities
    		                               -89,000 -69,000 -25,000 -10,000 23,000 32,000 48,000 75,000  162,000                                             
      reversal of deferred rent upon lease amendment
    		                               0 0                                                     
      accrued liabilities and other long-term liabilities
    		                                                                                     
      release of accrual for litigation settlement and insurance recovery
    		                               925,000 0 0 4,050,000                                                   
      revaluation of warrant liability
    		                                                                                     
      disposal of fully depreciated property and equipment
    		                        8,437,000 130,000 851,000 0 157,000 5,000 37,000     1,194,000 2,000 4,000 1,154,000 1,265,000 167,000 0 4,000 166,000 11,000 390,000 274,000 78,000 0 7,000 1,000 140,000 10,000 14,000 5,000    836,000     308,000 52,000 63,000 792,000     212,000 2,000 6,000 18,000 140,000          
      tax withholding from exercise of stock options and restricted stock awards
    		                          -18,000   -123,000 -426,000                                                       
      write-off of assets in progress
    		                                                                                     
      cash-settled portion of stock compensation expense
    		                                                                                     
      accrued liabilities and other long term liabilities
    		                           6,433,000 4,834,000 1,054,000 276,000 4,472,000 390,000 -301,000 -1,363,000 -11,473,000 2,874,000 656,000 -3,816,000 8,653,000 2,998,000 -277,000 -2,357,000 476,000 1,117,000 4,888,000 -1,671,000 198,000 269,000 -853,000 -1,905,000 905,000 1,831,000 1,024,000 -1,844,000 830,000 191,000 -403,000 -2,785,000 -6,566,000 2,886,000 3,997,000 3,064,000  674,000 -142,000 83,000                   
      deferred revenues
    		                                   0 0 -1,759,000 -895,000 -7,892,000 -818,000 -929,000 -472,000 6,266,000 -1,795,000 -2,040,000 3,036,000 -1,579,000 -1,289,000 -1,014,000 -888,000 3,121,000 776,000 -1,479,000 -946,000 4,584,000 -357,000 -358,000 -357,000 -357,000 -10,357,000 -1,312,000 -691,000 -766,000 -903,000 -13,227,000 -16,948,000 5,673,000 2,505,000 -176,000 -576,000 33,438,000 233,000 -200,000 -30,000 -649,000 10,598,000    -48,000 48,000 -7,000,000   
      (tax withholding) proceeds from exercise of stock options and restricted stock awards
    		                           6,000      0 -303,000                                                   
      accrual for litigation settlement and insurance recovery
    		                                   925,000 0                                                 
      return of unused development funding to astrazeneca ab
    		                                                                                     
      milestone payment from astrazeneca ab
    		                                                                                     
      common stock issuance costs - cash not paid as of period end
    		                                                                                     
      (gain) loss on disposal of property and equipment
    		                                                                                     
      accretion of debt discount related to debt financing
    		                                       0 -15,000 -49,000 -51,000                                           
      amortization of intangible assets
    		                                                       0 0 54,000 245,000 245,000 245,000 245,000 245,000 245,000 245,000 245,000 245,000 245,000 245,000 245,000 245,000 249,000 252,000 251,000 252,000 251,000 251,000         
      loss on extinguishment of debt
    		                                       0                                              
      restricted cash and other assets
    		                                  -907,000 -4,000 16,000 -79,000 -36,000 0    852,000 4,000 -845,000 266,000 10,000 152,000 1,000 13,000 -42,000 -5,000 14,000 -83,000 -126,000 14,000 -117,000 -61,000 2,016,000 -26,000 -1,004,000 -1,024,000  -10,000 -16,000 17,000                   
      payment of debt
    		                                       2,000                                              
      proceeds (withholding) from exercise of stock options and restricted stock awards
    		                                                                                     
      effect of exchange rate changes on cash and cash equivalents
    		                               102,000 184,000 331,000 57,000 -356,000 74,000 -62,000 92,000 -121,000 48,000 46,000 -276,000 -147,000 -209,000 -18,000 3,000                                       
      net increase in cash and cash equivalents
    		                                   1,268,000    -58,219,000   -34,798,000 29,855,000 2,624,000 -9,718,000 3,628,000 10,931,000 -5,394,000 -7,431,000 17,417,000             11,985,000 976,000 839,000 -5,183,000 5,485,000 7,748,000 -988,000 1,565,000 -349,000 8,139,000 -6,476,000 -1,175,000 -1,797,000   8,117,000 -10,443,000 14,052,000 -6,285,000 -5,189,000 -54,924,000 -2,445,000 
      cash and cash equivalents at beginning of year
    		                                               0 0 0 7,599,000                                   
      cash and cash equivalents at end of year
    		                                               10,931,000 -5,394,000 -7,431,000 25,016,000                                   
      net change in unrealized gain on marketable securities
    		                               -52,000 14,000 -16,000 -29,000 -15,000 -61,000 -41,000 109,000 7,000 5,000 -9,000 8,000 -37,000 -1,000 1,000 69,000 -53,000 18,000 -33,000 -8,000 16,000 59,000        -7,000                         
      cash-settled portion of stock-based compensation expense
    		                                    0 274,000 328,000 0 0                                             
      net decrease in cash and cash equivalents
    		                                  -2,817,000   -14,071,000 -5,954,000              -9,880,000 14,777,000 -12,188,000    -1,482,000  -844,000 -1,027,000 -6,640,000                       
      cash and cash equivalents at beginning of period
    		                                0 0 24,289,000  0 0 44,812,000  0 0 49,511,000  0 0 23,122,000      0 0 31,941,000  0 0 22,453,000  0 0 36,720,000  0 0 28,103,000  0 0 14,293,000  0 0 14,154,000  0 0 8,725,000  0 0 16,590,000   
      cash and cash equivalents at end of period
    		                                -17,579,000 16,203,000 21,472,000  -1,766,000 -14,071,000 38,858,000  66,545,000 21,773,000 14,713,000  2,624,000 -9,718,000 26,750,000      -9,880,000 14,777,000 19,753,000  -8,407,000 6,508,000 20,971,000  -844,000 -1,027,000 30,080,000  976,000 839,000 22,920,000  7,748,000 -988,000 15,858,000  8,139,000 -6,476,000 12,979,000  5,861,000 -6,752,000 16,842,000  14,052,000 -6,285,000 11,401,000   
      unoccupied facility expense
    		                                            131,000 178,000 77,000 8,000                                      
      (withholding) proceeds from exercise of stock options and restricted stock awards
    		                                                                                     
      return of unused development funding to astrazeneca ab “astrazeneca”
    		                                                                                     
      milestone payment from astrazeneca
    		                                                                                     
      accretion of end of term payment related to debt financing
    		                                         50,000 57,000                                           
      accounts receivable
    		                                      230,000 -231,000 -506,000 252,000 -182,000 0 565,000 438,000 -103,000 532,000 -134,000 -478,000 -542,000 2,680,000 -2,401,000 91,000 8,152,000 -8,744,000 356,000 -12,000 -126,000 254,000 94,000 -197,000 -257,000 289,000 335,000 1,459,000 3,429,000 -191,000 1,841,000 -1,917,000 1,094,000 -6,660,000 528,000 116,000 936,000 -269,000 -1,175,000 197,000 271,000  -317,000 8,213,000 -5,826,000  1,028,000 
      accretion of discounts and amortization of premiums of marketable securities
    		                                          171,000 167,000 214,000 236,000 264,000 231,000 162,000 250,000 280,000 328,000 332,000 334,000 304,000                               
      proceeds from long-term debt payable to hercules
    		                                                                                     
      loss on lease
    		                                                                                     
      interest associated with long-term note payable to symphony dynamo holdings llc
    		                                                                                     
      payment of notes payable to holdings
    		                                                                                     
      purchases of property and equipment, net of proceeds from asset disposals
    		                                            -288,000 -521,000 -398,000                                       
      payment of issuance costs
    		                                                                                     
      proceeds from issuances of common stock and warrants, net of issuance costs
    		                                                  -142,000                                   
      fair value adjustment of the warrant and contingent liabilities to holdings, including the impact of the anti-dilution provision associated with the common stock and warrants issued to symphony capital partners, l.p. and symphony strategic partners, llc
    		                                                                                     
      proceeds from issuances of warrants
    		                                                                                     
      interest associated with long-term note payable to holdings
    		                                                                                     
      payments and proceeds from issuances of common stock and warrants, net of issuance costs
    		                                                -1,000                                     
      effect of exchange rate on cash and cash equivalents
    		                                                125,000 33,000 -63,000 136,000 95,000 -196,000 83,000 -175,000 -155,000 38,000 74,000 -6,000 104,000 327,000 -448,000 -132,000 313,000 462,000 -408,000 -130,000 -602,000 9,000 60,000 35,000 73,000 10,000 -2,000 62,000 22,000   -1,000 0 0 -4,000   
      shares issued to aspire capital in conjunction with purchase agreement
    		                                                                                     
      shares issued in conjunction with the symphony dynamo, inc. (“sdi”) transaction
    		                                                                                     
      warrants issued in conjunction with the sdi transaction
    		                                                                                     
      gain on disposal of assets
    		                                                                                     
      non-cash interest associated with the note payable to holdings
    		                                                    547,000 548,000 547,000                               
      fair value adjustment of the warrant and contingent liabilities to holdings
    		                                                                                     
      proceeds from offering of common stock, net of issuance costs
    		                                                                                     
      (gain)/loss on disposal of assets
    		                                                        0                             
      proceeds from issuance of common stock, net of issuance costs
    		                                                        4,591,000 18,653,000 834,000 43,275,000 2,064,000 42,108,000 -48,000 -33,000                    -79,000 75,000 
      net income attributable to dynavax
    		                                                           -15,122,000 -4,998,000 -28,004,000 -9,184,000 -30,270,000 -9,506,000 4,110,000 5,101,000                   
      consideration paid in excess of carrying value of the noncontrolling interest in sdi
    		                                                                                     
      amount attributed to noncontrolling interest in sdi
    		                                                               -1,041,000 -1,200,000 -983,000 -1,009,000 -939,000                  
      non-cash interest associated with long-term note payable to holdings
    		                                                       468,000                              
      fair value adjustment of the warrant and contingent liabilities to holdings, including the impact of the anti-dilution provision associated with the common stock and warrants issued to symphony
    		                                                                                     
      interest associated with deerfield financing agreement
    		                                                               0       1,323,000               
      change in investments held by sdi
    		                                                               1,629,000 1,075,000 1,016,000 1,321,000 1,576,000 1,344,000 1,446,000 2,156,000               
      cash acquired from the purchase of noncontrolling interest in sdi
    		                                                                                     
      note payable issued to holdings from purchase option exercised under the sdi collaboration
    		                                                                                     
      shares issued in conjunction with the sdi transaction
    		                                                                                     
      liability from program option exercised under the sdi collaboration
    		                                                                        0             
      modification of warrants previously issued to deerfield
    		                                                                   9,000                  
      fair value adjustments to the common stock, warrant and contingent liability issued to holdings
    		                                                                                     
      accretion and amortization of marketable securities
    		                                                        278,000 263,000 354,000 242,000 83,000                         
      proceeds from the sale of property and equipment
    		                                                                                     
      proceeds from exercise of stock options and delivery of restricted stock units
    		                                                                                     
      disposal of fully depreciated assets
    		                                                        0                             
      net change in unrealized losses on marketable securities
    		                                                                                     
      non-cash interest associated with long-term note payable to symphony dynamo holdings llc
    		                                                         467,000 468,000                           
      fair value adjustment of the warrant and contingent liabilities to symphony dynamo holdings llc
    		                                                         20,000 -3,000                           
      net cash provided (used) by investing activities
    		                                                                                     
      fair value adjustment of the warrant and contingent liabilities to holdings, including the impact of the anti-dilution provision associate with the common stock and warrants issued to symphony
    		                                                                                     
      loan forgiveness
    		                                                                   0                  
      proceeds from notes payable issued to deerfield
    		                                                                   0 0 0 2,000,000               
      repayment of notes payable issued to deerfield
    		                                                                   0                  
      non-cash interest associated with deerfield financing agreement
    		                                                                                     
      non-cash interest associated with note payable to holdings
    		                                                            400,000                         
      fair value of the common stock, warrants and contingent liability issued to holdings
    		                                                                                     
      net cash (used in ) provided by investing activities
    		                                                                                     
      fair value of the common stock, warrant, and contingent liability to holdings
    		                                                                                     
      interest associated with note payable to holdings
    		                                                              399,000                       
      change in the fair value of the warrant and contingent consideration to holdings
    		                                                              -183,000                       
      proceeds from issuance of common stock under equity distribution agreement, net of issuance costs
    		                                                              919,000                       
      accretion and amortization on marketable securities
    		                                                               0 10,000 24,000 -30,000 -100,000 -88,000 -202,000 -331,000 -277,000 -339,000 -551,000 -688,000 -448,000 -17,000 60,000 109,000  210,000 322,000 318,000   
      inventory
    		                                                                       263,000 -15,000 -2,000 11,000           
      accrued liabilities
    		                                                                   -5,161,000 1,152,000 114,000 -2,234,000 900,000 1,136,000 -152,000 -954,000 3,812,000 -319,000 1,486,000 868,000  -639,000 309,000 -131,000  1,650,000 
      proceeds from purchase of noncontrolling interest by preferred shareholders in sdi, net of fees
    		                                                                                     
      non-cash activities:
    		                                                                                     
      note payable to holdings from purchase option exercised under the sdi collaboration
    		                                                                                     
      warrants issued in conjunction with the deerfield financing agreement
    		                                                                                     
      loss on the disposal of assets
    		                                                                                     
      acquired in-process research and development
    		                                                                           0 0         
      realized loss on investments
    		                                                                              23,000       
      cash paid for acquisition, net of cash acquired
    		                                                                           0 0         
      proceeds from purchase of noncontrolling interest by shareholders in sdi, net of fees
    		                                                                                     
      loss on disposal of assets
    		                                                                    23,000                 
      interest expense associated with deerfield financing agreement
    		                                                                    6,885,000                 
      proceeds from the purchase of noncontrolling interest in sdi, net of fees
    		                                                                                     
      supplemental disclosure of non-cash flow information
    		                                                                                     
      warrants issued in conjunction with deerfield financing agreement
    		                                                                                     
      amount attributed to noncontrolling interest in symphony dynamo, inc.
    		                                                                     -1,489,000 -1,566,000 -2,001,000 -1,621,000             
      realized gain on investments
    		                                                                                     
      interest accrued on notes receivable from stockholders
    		                                                                               0 -4,000 -5,000 -7,000 -9,000 -9,000 
      purchases of investments held by sdi
    		                                                                                     
      exercise of stock options
    		                                                                           1,029,000 162,000   13,000 0 -194,000 200,000   
      repayment of notes receivable from stockholders
    		                                                                               8,000 335,000 60,000 32,000 221,000 0 
      liability from program option exercised under the sdi transaction
    		                                                                                     
      repurchase of common stock for exercise of stock options
    		                                                                               0 0 0 -200,000   
      realized loss on sale of marketable securities
    		                                                                            0         
      increase in interest payable
    		                                                                                     
      purchases disposal of property and equipment
    		                                                                                     
      proceeds from deerfield financing agreement
    		                                                                                     
      issuance cost associated with common stock offering
    		                                                                        0 0 -19,000           
      supplemental disclosure of non-cash investing and financing activities
    		                                                                                     
      warrants issued in conjunction with sdi transaction
    		                                                                                     
      change in investments held by symphony dynamo, inc.
    		                                                                         -26,489,000 4,754,000           
      (purchases) disposal of property and equipment
    		                                                                                     
      proceeds from purchase of noncontrolling interest by preferred shareholders in symphony dynamo, inc., net of fees
    		                                                                            0         
      warrants issued in conjunction with the symphony dynamo, inc. transaction
    		                                                                           0 0         
      loss attributed to noncontrolling interest in symphony dynamo, inc.
    		                                                                          -2,016,000  -3,271,000         
      maturities and sales of marketable securities
    		                                                                          25,699,000 13,250,000 18,440,000 19,019,000 23,286,000 9,817,000 24,862,000 12,645,000 18,545,000   
      purchases of investments held by symphony dynamo, inc.
    		                                                                           4,364,000 1,317,000         
      proceeds from purchase of noncontrolling interest by shareholders in symphony dynamo, inc., net of fees
    		                                                                                     
      restricted cash
    		                                                                                   0 -331,000 
      change in unrealized gain on marketable securities
    		                                                                                     
      lease incentive
    		                                                                                     
      conversion of preferred stock upon initial public offering
    		                                                                                     
      conversion of ordinary shares in dynavax asia upon initial public offering
    		                                                                                     
      interest accrued on notes receivable
    		                                                                                     
      change in unrealized loss on marketable securities
    		                                                                            79,000         
      change in cumulative translation adjustment
    		                                                                            22,000   -1,000 0 0 -4,000   
      disposal (purchases) of property and equipment
    		                                                                                     
      net increase increase in cash and cash equivalents
    		                                                                                     
      adjustments to reconcile net income (income) to net cash from operating activities:
    		                                                                                     
      amortization of stock-based compensation expense
    		                                                                              666,000 439,000 308,000 336,000 317,000 793,000 728,000 
      net change in unrealized loss on marketable securities
    		                                                                              29,000 -48,000      
      loss on disposal of property and equipment
    		                                                                                   0 1,000 
      realized loss on investment
    		                                                                                     
      proceeds from issuance of ordinary shares in dynavax asia, net of issuance costs
    		                                                                                     
      repurchase of common stock
    		                                                                                     
      repurchase of common stock for notes receivable
    		                                                                                     
      deemed dividend upon issuance of ordinary shares of dynavax asia
    		                                                                                     
      conversion of ordinary shares in dynavax asia upon initial public offering.
    		                                                                                     
      net unrealized loss on marketable securities
    		                                                                                 41,000 -59,000   
      proceeds from issuance of preferred stock, net of issuance costs
    		                                                                                     
      repayments of equipment financing
    		                                                                                     
      accretion and amortization on investments
    		                                                                                    0 
      purchase of marketable securities
    		                                                                                     
      maturities and sale of marketable securities
    		                                                                                    0 
      cash and cash equivalents at beginning of the period
    		                                                                                    0 
      cash and cash equivalents at end of the period
    		                                                                                    -2,445,000 
      
    		                                                                                     
    The information provided in this report is taken from www.sec.gov and many other data providers. While we have conducted our best efforts to ensure that the parsed data is accurate, we cannot guarantee its accuracy. Please use caution and understand that any consequences of its use are your own responsibility.