7Baggers

Design Therapeutics, Inc
(NASDAQ:DSGN) 

DSGN stock logo

Design Therapeutics, Inc. develops therapies for the treatment of degenerative disorders caused by nucleotide repeat expansions. The company engages in the development of a program for the treatment of Friedreich's ataxia and degenerative diseases such as Fragile X syndrome and myotonic dystrophy. T...

Founded: 2017
Sector: Healthcare
Industry: Biotechnology

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At a glance:
Bull Thesis:
Bear Thesis:
Main Competitors:
Moat:
Income Statements:
Quarterly
Annual
    Unit: USD2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 
                       
      operating expenses:
                       
      research and development
    14,589,000 15,738,000 15,377,000 12,157,000 11,876,000 10,516,000 9,801,000 11,012,000 13,257,000 17,064,000 15,730,000 14,255,000 14,304,000 11,295,000 8,759,000 7,337,000 8,539,000 5,027,000 3,875,000 
      general and administrative
    4,722,000 5,831,000 5,041,000 4,537,000 4,370,000 4,527,000 4,599,000 4,109,000 5,565,000 5,532,000 5,921,000 5,137,000 4,888,000 4,344,000 4,611,000 3,790,000 2,798,000 2,660,000 1,805,000 
      total operating expenses
    19,311,000 21,569,000 20,418,000 16,694,000 16,246,000 15,043,000 14,400,000 15,121,000 18,822,000 22,596,000 21,651,000 19,392,000 19,192,000 15,639,000 13,370,000 11,127,000 11,337,000 7,687,000 5,680,000 
      income from operations
    -19,311,000 -21,569,000 -20,418,000 -16,694,000 -16,246,000 -15,043,000 -14,400,000 -15,121,000 -18,822,000 -22,596,000 -21,651,000 -19,392,000 -19,192,000 -15,639,000 -13,370,000 -11,127,000 -11,337,000 -7,687,000 -5,680,000 
      yoy
    18.87% 43.38% 41.79% 10.40% -13.69% -33.43% -33.49% -22.02% -1.93% 44.48% 61.94% 74.28% 69.29% 103.45% 135.39%     
      qoq
    -10.47% 5.64% 22.31% 2.76% 8.00% 4.47% -4.77% -19.66% -16.70% 4.36% 11.65% 1.04% 22.72% 16.97% 20.16% -1.85% 47.48% 35.33%  
      interest income
    2,314,000 2,486,000 2,703,000                 
      net income
    -16,997,000 -19,083,000 -17,715,000 -13,651,000 -13,039,000 -11,793,000 -11,105,000 -11,842,000 -15,789,000 -19,937,000 -19,294,000 -17,340,000 -17,704,000 -14,999,000 -13,265,000 -11,065,000 -11,318,000 -7,636,000 -5,514,000 
      yoy
    30.36% 61.82% 59.52% 15.28% -17.42% -40.85% -42.44% -31.71% -10.82% 32.92% 45.45% 56.71% 56.42% 96.42% 140.57%     
      qoq
    -10.93% 7.72% 29.77% 4.69% 10.57% 6.20% -6.22% -25.00% -20.81% 3.33% 11.27% -2.06% 18.03% 13.07% 19.88% -2.24% 48.22% 38.48%  
      net income per share
    -0.3 -0.34 -0.31 -0.24 -0.23 -0.21 -0.2 -0.21 -0.28 -0.36 -0.35 -0.31 -0.32 -0.27 -0.24 -0.2 -0.21 -0.14 -0.31 
      weighted-average shares of common stock outstanding, basic and diluted
    56,950,999 56,859,388 56,757,827 56,587,142 56,620,731 56,555,960 56,488,527 55,984,670 55,988,691 55,948,990 55,908,033 55,707,517 55,782,329 55,670,780 55,507,338 45,936,235 55,155,030 55,081,397 17,630,178 
      other income
       2,438,000 3,207,000 3,250,000 3,295,000 3,279,000 3,033,000 2,659,000 2,357,000 2,052,000 1,488,000 640,000 105,000 62,000 19,000 51,000 166,000 
      revenue:
                       
      grant revenue
                       
    Balance Sheets:
    Quarterly
    Annual
      Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 
                           
        assets
                           
        current assets:
                           
        cash and cash equivalents
      12,770,000 16,856,000 15,088,000 19,703,000 13,667,000 22,563,000 30,328,000 45,699,000 29,397,000 21,200,000 27,942,000 27,197,000 28,809,000 26,500,000 42,517,000 119,654,000 287,312,000 298,569,000 357,662,000 370,838,000 400,693,000 
        investment securities
      210,053,000 202,989,000 190,882,000 196,573,000 216,007,000 222,914,000 223,746,000 215,317,000 241,289,000 260,598,000 262,998,000 275,891,000 286,583,000 303,887,000 301,716,000 239,723,000 83,908,000 85,495,000 36,056,000 31,998,000 10,646,000 
        prepaid expenses and other current assets
      4,226,000 3,939,000 3,059,000 3,518,000 3,970,000 2,563,000 3,168,000 3,826,000 3,200,000 2,786,000 3,603,000 2,957,000 3,547,000 4,732,000    1,371,000    
        total current assets
      227,049,000 223,784,000 209,029,000 219,794,000 233,644,000 248,040,000 257,242,000 264,842,000 273,886,000 284,584,000 294,543,000 306,045,000 318,939,000 335,119,000 348,488,000 361,722,000 373,871,000 385,435,000 395,290,000 404,875,000 411,754,000 
        property and equipment
      824,000 981,000 1,104,000 1,258,000 1,377,000 1,410,000 1,559,000 1,728,000 1,718,000 1,691,000 1,778,000 1,861,000 1,905,000 1,947,000 1,842,000 1,804,000 1,448,000 1,508,000 1,320,000 271,000 100,000 
        right-of-use asset
      2,569,000                  3,743,000   
        total assets
      230,442,000 226,203,000 211,770,000 222,886,000 237,475,000 252,093,000 261,629,000 269,582,000 278,793,000 289,643,000 299,869,000 311,630,000 324,743,000 341,137,000 354,569,000 367,932,000 378,801,000 390,557,000 400,353,000 405,146,000 411,854,000 
        liabilities and stockholders’ equity
                           
        current liabilities:
                           
        accounts payable
      2,276,000 2,312,000 1,913,000 1,013,000 3,180,000 2,186,000 1,470,000 1,297,000 1,372,000 1,940,000 2,207,000 1,922,000 2,744,000 3,025,000 2,622,000 2,071,000 1,901,000 1,620,000 2,216,000 1,585,000 2,033,000 
        accrued expenses and other current liabilities
      7,914,000 10,743,000 9,260,000 7,734,000 5,056,000 6,276,000 5,962,000 5,097,000 5,722,000 7,682,000 10,183,000 10,211,000 6,303,000 7,751,000 7,790,000 5,317,000 3,579,000 3,663,000 3,289,000   
        total current liabilities
      10,190,000 13,055,000 11,173,000 8,747,000 8,236,000 8,462,000 7,432,000 6,394,000 7,094,000 9,622,000 12,390,000 12,133,000 9,047,000 10,776,000 10,412,000 7,388,000 5,480,000 5,283,000 5,505,000 3,405,000 3,706,000 
        operating lease liability
      2,198,000                  3,273,000   
        total liabilities
      12,388,000 13,700,000 12,050,000 9,849,000 9,556,000 9,996,000 9,176,000 8,340,000 9,236,000 11,956,000 14,912,000 14,835,000 11,925,000 13,827,000 13,631,000 10,769,000 8,492,000 8,427,000 8,789,000 3,545,000 3,848,000 
        commitments and contingencies
                           
        stockholders’ equity:
                           
        common stock, 0.0001 par value...
      6,000  6,000 6,000 6,000  6,000 6,000 6,000  6,000 6,000 6,000  6,000 6,000 6,000  6,000 6,000  
        additional paid-in capital
      532,958,000 509,100,000 480,365,000 476,738,000 472,392,000 468,830,000 465,096,000 461,977,000 458,449,000 455,245,000 452,018,000 448,784,000 444,852,000 441,424,000 438,217,000 435,192,000 432,346,000 429,824,000 427,953,000 426,680,000 425,435,000 
        accumulated deficit
      -314,642,000 -297,006,000 -281,009,000 -264,012,000 -244,929,000 -227,214,000 -213,563,000 -200,524,000 -188,731,000 -177,626,000 -165,784,000 -149,995,000 -130,058,000 -110,764,000 -93,424,000 -75,720,000 -60,721,000 -47,456,000 -36,391,000 -25,073,000 -17,437,000 
        accumulated other comprehensive income
      -268,000 403,000 358,000 305,000 450,000 475,000 914,000 -217,000 -167,000         -244,000 -4,000 -12,000 2,000 
        total stockholders’ equity
      218,054,000  199,720,000 213,037,000 227,919,000  252,453,000 261,242,000 269,557,000  284,957,000 296,795,000 312,818,000  340,938,000 357,163,000 370,309,000  391,564,000 401,601,000 408,006,000 
        total liabilities and stockholders’ equity
      230,442,000  211,770,000 222,886,000 237,475,000  261,629,000 269,582,000 278,793,000  299,869,000 311,630,000 324,743,000  354,569,000 367,932,000 378,801,000     
        right-of-use asset, related party
       1,438,000 1,637,000 1,834,000 2,027,000 2,216,000 2,401,000 2,583,000 2,762,000 2,938,000 3,111,000 3,280,000 3,447,000 3,612,000 3,773,000 3,932,000 3,482,000 3,614,000    
        other assets
          427,000 427,000 427,000 429,000 427,000 430,000 437,000 444,000 452,000 459,000 466,000 474,000      
        liabilities and stockholders' equity
                           
        operating lease liability, net, related party
       645,000 877,000 1,102,000 1,320,000 1,534,000 1,744,000 1,946,000 2,142,000 2,334,000 2,522,000 2,702,000 2,878,000 3,051,000 3,219,000 3,381,000 3,012,000 3,144,000    
        stockholders' equity:
                           
        common stock: 0.0001 par value...
       6,000    6,000    6,000    6,000    6,000    
        total stockholders' equity
       212,503,000    242,097,000    277,687,000    327,310,000    382,130,000    
        total liabilities and stockholders' equity
       226,203,000    252,093,000    289,643,000    341,137,000        
        accumulated other comprehensive loss
               62,000 -1,283,000 -2,000,000 -1,982,000 -3,356,000 -3,861,000 -2,315,000 -1,322,000     
        prepaid expense and other current assets
                    4,255,000 2,345,000 2,651,000  1,572,000 2,039,000 415,000 
        deferred offering costs
                           
        liabilities, convertible preferred stock and stockholders' equity
                           
        other long-term liabilities
                        11,000 140,000 142,000 
        convertible preferred stock; 0.0001 par value...
                           
        stockholders' equity
                           
        total liabilities, convertible preferred stock and stockholders' equity
                       390,557,000    
        liabilities, convertible preferred stock and stockholders’ equity
                           
        convertible preferred stock, 0.0001 par value...
                           
        stockholders’ equity
                           
        total liabilities, convertible preferred stock and stockholders’ equity
                        400,353,000 405,146,000 411,854,000 
        accrued expenses
                         1,820,000 1,673,000 
        common stock, par value 0.0001...
                          6,000 
      Cashflow Statements:
      Quarterly
      Annual
        Unit: USD2026-03-31 2025-12-31 2025-09-30 2025-06-30 2025-03-31 2024-12-31 2024-09-30 2024-06-30 2024-03-31 2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 
                             
          cash flows from operating activities
                             
          net loss
        -17,636,000 -15,997,000 -16,997,000 -19,083,000 -17,715,000 -13,651,000 -13,039,000 -11,793,000 -11,105,000 -11,842,000 -15,789,000 -19,937,000 -19,294,000 -17,340,000 -17,704,000 -14,999,000 -13,265,000 -11,065,000 -11,318,000 -7,636,000 -5,514,000 
          reconciliation of net loss to net cash from operating activities:
                             
          depreciation
        157,000 156,000 155,000 152,000 159,000 149,000 153,000 151,000 143,000 138,000 137,000 133,000 129,000 124,000 108,000 92,000 82,000 82,000 31,000 12,000 4,000 
          stock-based compensation
        3,924,000 3,435,000 3,590,000 3,985,000 3,539,000 3,471,000 3,118,000 3,299,000 3,184,000 2,724,000 3,219,000 3,719,000 3,426,000 3,076,000 2,872,000 2,617,000 2,360,000 1,556,000 1,243,000 1,243,000 647,000 
          amortization of premiums on investment securities
        -147,000 -512,000 -767,000 -914,000 -1,060,000 -1,438,000 -1,456,000 -1,573,000 -1,731,000 -1,836,000 -1,709,000 -1,397,000 -1,142,000 -899,000 -458,000 -58,000 19,000 26,000 25,000 22,000 -150,000 
          non-cash lease expense
        69,000 -8,000 -7,000 -2,000 -4,000 -3,000 1,000 4,000 4,000 5,000 8,000 10,000 10,000 11,000 14,000 21,000 14,000     
          change in operating assets and liabilities:
                             
          prepaid expense and other assets
        -287,000 -880,000 459,000 452,000 -1,407,000 605,000 660,000 -628,000 -411,000 823,000 -639,000 598,000 1,192,000 -471,000 -1,902,000 217,000 -1,237,000 141,000 466,000   
          accounts payable and other liabilities
        -2,511,000 1,840,000 2,405,000 542,000 -301,000 1,007,000 1,017,000 -720,000 -2,523,000 -2,810,000 239,000 3,070,000 -1,745,000 431,000 3,156,000 1,598,000 215,000 -26,000    
          net cash from operating activities
        -16,431,000 -11,966,000 -11,162,000 -14,441,000 -16,789,000 -9,860,000 -9,546,000 -11,260,000 -12,439,000 -12,798,000 -14,534,000 -13,804,000 -17,424,000 -15,091,000 -13,899,000 -10,500,000 -11,827,000 -9,227,000 -8,164,000 -8,289,000 -3,697,000 
          capital expenditures
         -34,000 -87,000 -18,000 16,000 -161,000 -195,000 -27,000 -53,000 -89,000  -288,000 -473,000 -41,000 -57,000 -354,000 -968,000 -183,000 -33,000 
          free cash flows
         -12,000,000 -11,162,000 -14,528,000 -16,807,000 -9,860,000 -9,530,000 -11,421,000 -12,634,000 -12,825,000 -14,587,000 -13,893,000  -15,379,000 -14,372,000 -10,541,000 -11,884,000 -9,581,000 -9,132,000 -8,472,000 -3,730,000 
          cash flows from investing activities
                             
          purchases of investment securities
        -52,589,000 -87,624,000 -78,075,000 -39,532,000 -86,548,000 -64,373,000 -66,512,000 -53,631,000 -45,659,000 -74,153,000 -54,566,000 -62,369,000 -33,615,000 -61,008,000 -94,014,000   -49,905,000 -4,319,000 -26,926,000 -5,111,000 
          proceeds from maturities of investment securities
        45,000,000 76,075,000 84,585,000 59,735,000 94,490,000 66,205,000 60,670,000 81,125,000 66,470,000 79,735,000 69,885,000 74,440,000 53,435,000 60,240,000 30,935,000 1,225,000 490,000 200,000 245,000 5,538,000 28,172,000 
          purchases of property and equipment
         -34,000 -87,000 -72,000 16,000 -161,000 -195,000 -27,000 -53,000 -89,000 -87,000 -288,000 -310,000 -244,000 -76,000 -354,000 -968,000 -183,000 -33,000 
          net cash from investing activities
        -7,589,000 -11,583,000 6,510,000 20,116,000 7,870,000 1,832,000 -5,826,000 27,333,000 20,616,000  15,266,000 11,982,000 19,733,000 -1,056,000 -63,389,000 -156,956,000 414,000 -50,059,000 -5,042,000 -21,571,000 23,028,000 
          cash flows from financing activities
                             
          proceeds from the issuance of common stock in at-the-market offering, net of issuance costs
        19,907,000                     
          proceeds from the exercise of stock options
        27,000 182,000 37,000 23,000 9,000 1,000 6,000 20,000 402,000 13,000   16,000 151,000 156,000     
          net cash from financing activities
        19,934,000 25,317,000 37,000 361,000 23,000 263,000 1,000 229,000 20,000 501,000 13,000   130,000 151,000 -202,000 156,000 193,000 30,000 5,000 378,983,000 
          net decrease in cash and cash equivalents
        -4,086,000                     
          cash and cash equivalents at beginning of period
        16,856,000 22,563,000 21,200,000 26,500,000 298,569,000 2,379,000 
          cash and cash equivalents at end of period
        12,770,000 1,768,000 -4,615,000 6,036,000 13,667,000 -7,765,000 -15,371,000 16,302,000 29,397,000 -6,742,000 745,000 -1,612,000 28,809,000 -16,017,000 -77,137,000 -167,658,000 287,312,000 -59,093,000 -13,176,000 -29,855,000 400,693,000 
          supplemental disclosures
                             
          increase in right-of-use-asset and operating lease liability related to lease amendment
        1,295,000                     
          purchases of property and equipment included in accounts payable and accrued expenses
            54,000          -163,000 203,000 19,000     
          deferred financing costs
                           
          issuance of common stock through employee stock purchase plan
         288,000   254,000   99,000   114,000       
          issuance costs included in accrued expenses
                             
          net increase in cash and cash equivalents
          -4,615,000 6,036,000 -8,896,000  -15,371,000 16,302,000 8,197,000  745,000 -1,612,000 2,309,000 -16,017,000 -77,137,000 -167,658,000 -11,257,000 -59,093,000 -13,176,000 -29,855,000 398,314,000 
          purchases of property and equipment included in accrued expenses
                             
          other
                           
          accounts payable and other liabilities—related party
                     -23,000 15,000 8,000 -15,000 -15,000    
          proceeds from sale of asset
                           
          net cash from (used) in investing activities
                             
          payment of deferred issuance costs
                           
          initial recognition of operating lease right-of-use asset and operating lease liability
                            
          initial recognition of right-of-use asset and operating lease liability
                            
          deferred financing costs in accrued expenses
                            
          proceeds from initial public offering, net of issuance costs
                         254,271,000 
          proceeds from issuance of convertible preferred stock, net of issuance costs
                         124,712,000 
          prepaid expense and other assets—related party
                          -60,000 
          non-cash interest expense
                             
          non-cash interest expense—related party
                             
          net change in operating lease right-of-use assets and liabilities—related party
                             
          deferred revenue
                             
          other long-term liabilities
                             
          proceeds from the issuance of notes payable, net of issuance costs—related party
                             
          repayment of notes payable—related party
                             
          conversion of convertible notes to convertible preferred shares, including bifurcated conversion liability
                             
          conversion of convertible notes to convertible preferred shares, including bifurcated conversion liability - related party
                             
          interest paid
                             
          proceeds from the exercise of stock options and vesting of restricted stock
                          30,000   
          accounts payable and accrued liabilities
                           -301,000 1,376,000 
          accounts payable and accrued liabilities—related party