Day One Biopharmaceuticals Inc(NASDAQ:DAWN) 
We are a unique company created to find and develop new therapies that meet the critical needs of people of all ages living with cancer – starting from the biology of childhood cancer. Our distinctive approach, together with our trusted network of pediatric oncology investigators, gives us an unpara...
Website: https://dayonebio.com/
Founded: 2018
IPO Price: $16 (May 27, 2021)
CEO: Jeremy Bender
Sector:
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At a glance:
Bull Thesis:
Bear Thesis:
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Moat:
Income Statements:
Quarterly
Annual
| Unit: USD | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
revenue: | |||||||||||||||||||
product revenue | 52,834,000 | 38,522,000 | 33,562,000 | 30,503,000 | 28,955,000 | 20,070,000 | 8,192,000 | ||||||||||||
license revenue | 884,000 | 1,273,000 | 346,000 | 258,000 | 253,000 | 73,691,000 | |||||||||||||
total revenues | 53,718,000 | 39,795,000 | 33,908,000 | 30,761,000 | 29,208,000 | 93,761,000 | |||||||||||||
yoy | 83.92% | -57.56% | |||||||||||||||||
qoq | 34.99% | 17.36% | 10.23% | 5.32% | -68.85% | ||||||||||||||
cost and operating expenses: | |||||||||||||||||||
cost of product and license revenue | 2,782,250 | 4,480,000 | 3,765,000 | ||||||||||||||||
research and development | 40,948,000 | 31,419,000 | 36,149,000 | 39,619,000 | 61,823,000 | 33,563,000 | 92,106,000 | 40,210,000 | 37,348,000 | 33,163,000 | 32,182,000 | 27,828,000 | 26,020,000 | 22,035,000 | 22,560,000 | 15,003,000 | 11,189,000 | 9,849,000 | 9,914,000 |
selling, general and administrative | 34,147,000 | 28,147,000 | 28,968,000 | 29,325,000 | 29,735,000 | 28,972,000 | 30,186,000 | ||||||||||||
total cost and operating expenses | 81,176,000 | 64,046,000 | 68,882,000 | 71,828,000 | 94,540,000 | 64,125,000 | 122,999,000 | ||||||||||||
income from operations | -27,458,000 | -24,251,000 | -34,974,000 | -41,067,000 | -65,332,000 | 29,636,000 | -114,807,000 | -66,767,000 | -59,517,000 | -51,438,000 | -49,254,000 | -45,855,000 | -42,743,000 | -39,699,000 | -36,719,000 | -27,748,000 | -21,975,000 | -19,241,000 | -15,439,000 |
yoy | -57.97% | -181.83% | -69.54% | -38.49% | 9.77% | -157.61% | 133.09% | 45.60% | 39.24% | 29.57% | 34.14% | 65.26% | 94.51% | 106.33% | 137.83% | ||||
qoq | 13.22% | -30.66% | -14.84% | -37.14% | -320.45% | -125.81% | 71.95% | 12.18% | 15.71% | 4.43% | 7.41% | 7.28% | 7.67% | 8.12% | 32.33% | 26.27% | 14.21% | 24.63% | |
operating margin % | -51.12% | -60.94% | -103.14% | -133.50% | -223.68% | 31.61% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% | -Infinity% |
non-operating income: | |||||||||||||||||||
gain from sale of priority review voucher | 108,000,000 | ||||||||||||||||||
investment income | 4,147,000 | 4,559,000 | 4,671,000 | 5,094,000 | 6,052,000 | 5,322,000 | 3,962,000 | 4,365,000 | 5,024,000 | 5,291,000 | 3,406,000 | 3,466,000 | |||||||
other income | 57,000 | -34,000 | 40,000 | 1,197,000 | -5,500 | -3,000 | 2,000 | 9,000 | |||||||||||
total non-operating income | 4,204,000 | 4,525,000 | 4,652,000 | 5,071,000 | 6,092,000 | 6,519,000 | 111,952,000 | ||||||||||||
income before income taxes | -23,254,000 | -19,726,000 | -30,322,000 | -35,996,000 | -59,240,000 | 36,155,000 | -2,855,000 | ||||||||||||
income tax benefit | -167,500 | 882,000 | |||||||||||||||||
net income | -21,278,000 | -19,726,000 | -30,322,000 | -35,996,000 | -65,714,000 | 37,037,000 | -4,407,000 | -40,109,000 | -37,795,000 | -36,530,000 | |||||||||
yoy | -67.62% | -153.26% | 588.04% | ||||||||||||||||
qoq | 7.87% | -34.94% | -15.76% | -45.22% | -277.43% | -940.41% | 6.12% | 3.46% | |||||||||||
net income margin % | -39.61% | -49.57% | -89.42% | -117.02% | -224.99% | 39.50% | -Infinity% | NaN% | NaN% | NaN% | NaN% | NaN% | -Infinity% | -Infinity% | -Infinity% | NaN% | NaN% | NaN% | NaN% |
net income per share | -0.21 | -0.19 | -0.29 | -0.35 | -0.69 | 0.38 | -0.05 | -0.72 | -0.64 | -0.54 | -0.61 | -0.59 | -0.56 | -0.53 | -0.6 | -0.48 | 0.36 | -0.33 | -5.04 |
weighted-average number of common shares used in net income per share - basic | 103,381,315 | 96,623,123 | |||||||||||||||||
weighted-average number of common shares used in net income per share - diluted | 103,381,315 | 96,937,759 | |||||||||||||||||
other expense | -19,000 | -23,000 | -10,000 | -10,000 | -15,000 | -4,000 | -1,000 | 14,000 | 7,000 | -27,000 | |||||||||
income tax expense | -1,552,000 | ||||||||||||||||||
weighted-average number of common shares used in net loss per share - basic | 103,205,703 | 103,069,154 | 102,710,382 | 93,234,195 | |||||||||||||||
weighted-average number of common shares used in net loss per share - diluted | 103,205,703 | 103,069,154 | 102,710,382 | 93,234,195 | |||||||||||||||
cost of product revenue | 2,884,000 | 2,982,000 | 1,590,000 | 707,000 | |||||||||||||||
weighted-average number of common shares used in computing net loss per share, basic and diluted | 87,121,310 | 86,679,282 | 79,773,004 | 85,952,501 | 74,964,878 | 71,972,888 | 65,466,773 | 71,008,993 | 60,760,527 | 58,382,444 | 36,960,569 | 57,514,218 | 22,661,889 | ||||||
operating expenses: | |||||||||||||||||||
general and administrative | 26,557,000 | 22,169,000 | 18,275,000 | 17,072,000 | 18,027,000 | 16,723,000 | 17,664,000 | 14,159,000 | 12,745,000 | 10,786,000 | 9,392,000 | 5,525,000 | |||||||
total operating expenses | 66,767,000 | 59,517,000 | 51,438,000 | 49,254,000 | 45,855,000 | 42,743,000 | 39,699,000 | 36,719,000 | 27,748,000 | 21,975,000 | 19,241,000 | 15,439,000 | |||||||
net loss attributable to common stockholders | -62,412,000 | -33,601,500 | -46,150,000 | -45,863,000 | -42,393,000 | ||||||||||||||
interest income | 2,660,000 | 1,895,000 | 189,000 | 2,000 | |||||||||||||||
net loss attributable to redeemable convertible noncontrolling interest | |||||||||||||||||||
exchange of redeemable noncontrolling interest shares – deemed dividend | -99,994,000 | ||||||||||||||||||
net loss attributable to common stockholders/members | -40,109,000 | -37,795,000 | -36,530,000 | -27,747,000 | |||||||||||||||
net loss and comprehensive loss | -27,747,000 | -21,938,000 | -19,240,000 | -15,473,000 | |||||||||||||||
interest expense | -4,750 | -6,000 | -7,000 | ||||||||||||||||
changes in fair value of derivative tranche liability | |||||||||||||||||||
net loss attributable to redeemable convertible noncontrolling interests | -1,191,000 | ||||||||||||||||||
net loss attributable to common share members/common stockholders | -37,175,250 | -19,240,000 | -114,276,000 |
Balance Sheets:
Quarterly
Annual
| Unit: USD | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 | 2021-06-30 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
assets | |||||||||||||||||||
current assets: | |||||||||||||||||||
cash and cash equivalents | 197,078,000 | 43,277,000 | 35,622,000 | 33,358,000 | 124,968,000 | 422,765,000 | 239,616,000 | 270,391,000 | 230,784,000 | 241,179,000 | 189,211,000 | 49,268,000 | 85,262,000 | 120,864,000 | 388,877,000 | 262,731,000 | 284,309,000 | 297,160,000 | 309,996,000 |
short-term investments | 244,035,000 | 408,303,000 | 417,481,000 | 439,662,000 | 406,752,000 | 135,618,000 | 122,250,000 | 47,553,000 | 135,563,000 | 164,359,000 | 253,671,000 | 268,911,000 | 257,007,000 | 253,477,000 | 5,987,000 | ||||
accounts receivable | 26,735,000 | 16,697,000 | 19,669,000 | 18,054,000 | 13,876,000 | 8,695,000 | 9,136,000 | ||||||||||||
inventory | 6,326,000 | 7,061,000 | 6,543,000 | 3,565,000 | 3,321,000 | 2,735,000 | 151,000 | ||||||||||||
prepaid expenses and other current assets | 10,925,000 | 14,633,000 | 15,113,000 | 14,012,000 | 13,413,000 | 11,183,000 | 12,005,000 | 8,090,000 | 8,927,000 | 7,753,000 | 6,902,000 | 4,209,000 | 5,605,000 | 6,172,000 | 7,639,000 | 4,637,000 | 5,059,000 | 6,151,000 | 6,029,000 |
total current assets | 485,099,000 | 489,971,000 | 494,428,000 | 508,651,000 | 562,330,000 | 580,996,000 | 383,158,000 | 326,034,000 | 375,274,000 | 413,291,000 | 449,784,000 | 322,388,000 | 347,874,000 | 380,513,000 | 402,503,000 | 267,368,000 | 289,368,000 | 303,311,000 | 316,025,000 |
property and equipment | 2,136,000 | 2,227,000 | 2,317,000 | 2,508,000 | 2,285,000 | 904,000 | 196,000 | 185,000 | 208,000 | 213,000 | 183,000 | 72,000 | 20,000 | 35,000 | 67,000 | 66,000 | 57,000 | 62,000 | 67,000 |
operating lease right-of-use asset | 2,342,000 | 2,450,000 | 2,499,000 | 2,577,000 | 2,422,000 | 2,574,000 | 164,000 | 259,000 | 352,000 | 442,000 | 530,000 | 616,000 | 699,000 | 864,000 | 993,000 | 180,000 | 227,000 | 273,000 | 319,000 |
intangible assets | 18,020,000 | 18,815,000 | 19,610,000 | 20,405,000 | 15,630,000 | 16,216,000 | 16,802,000 | ||||||||||||
deposits and other long-term assets | 230,000 | 317,000 | 183,000 | 215,000 | 121,000 | 117,000 | 117,000 | 167,000 | 214,000 | 233,000 | 259,000 | 487,000 | 469,000 | 449,000 | 484,000 | 165,000 | 169,000 | 137,000 | 126,000 |
total assets | 507,827,000 | 513,780,000 | 519,037,000 | 534,356,000 | 582,788,000 | 600,807,000 | 400,437,000 | 326,645,000 | 376,048,000 | 414,179,000 | 450,756,000 | 323,563,000 | 349,062,000 | 381,861,000 | 404,047,000 | 267,779,000 | 289,821,000 | 303,783,000 | 316,537,000 |
liabilities and stockholders’ equity | |||||||||||||||||||
current liabilities: | |||||||||||||||||||
accounts payable | 3,733,000 | 5,778,000 | 5,090,000 | 2,540,000 | 3,262,000 | 3,017,000 | 6,444,000 | 4,780,000 | 2,576,000 | 3,391,000 | 4,565,000 | 4,657,000 | 260,000 | 3,973,000 | 439,000 | 701,000 | 1,744,000 | 683,000 | 348,000 |
accrued expenses and other current liabilities | 54,615,000 | 48,210,000 | 44,131,000 | 43,641,000 | 68,625,000 | 35,189,000 | 87,072,000 | 24,759,000 | 26,524,000 | 20,647,000 | 19,519,000 | 17,774,000 | 15,950,000 | 13,836,000 | 11,933,000 | 7,304,000 | 6,709,000 | 5,161,000 | 4,113,000 |
current portion of deferred revenue | 2,000,000 | 2,317,000 | 1,847,000 | 1,636,000 | 1,554,000 | 1,462,000 | |||||||||||||
current portion of operating lease liabilities | 174,000 | 161,000 | 153,000 | 62,000 | 10,000 | 77,000 | 300,000 | 408,000 | 437,000 | 428,000 | 417,000 | 405,000 | 462,000 | 427,000 | 171,000 | 204,000 | 202,000 | 201,000 | |
total current liabilities | 60,522,000 | 56,466,000 | 51,221,000 | 47,879,000 | 73,451,000 | 39,745,000 | 93,706,000 | 29,839,000 | 29,508,000 | 24,475,000 | 24,512,000 | 22,848,000 | 16,615,000 | 18,271,000 | 12,799,000 | 8,176,000 | 8,657,000 | 6,046,000 | 4,662,000 |
long-term portion of deferred revenue | 3,040,000 | 2,953,000 | 3,371,000 | 3,350,000 | 3,233,000 | 3,061,000 | |||||||||||||
long-term portion of operating lease liabilities | 2,619,000 | 2,732,000 | 2,850,000 | 2,854,000 | 2,592,000 | 2,538,000 | |||||||||||||
other long-term liability | 484,000 | 761,000 | 761,000 | 761,000 | 761,000 | ||||||||||||||
total liabilities | 66,665,000 | 62,912,000 | 58,203,000 | 54,844,000 | 80,037,000 | 45,344,000 | 93,706,000 | 29,839,000 | 29,508,000 | 24,552,000 | 24,702,000 | 23,148,000 | 17,023,000 | 18,785,000 | 13,416,000 | 8,176,000 | 8,673,000 | 6,111,000 | 4,774,000 |
commitments and contingencies | |||||||||||||||||||
stockholders’ equity: | |||||||||||||||||||
common stock, 0.0001 par value... | 10,000 | 10,000 | 10,000 | 10,000 | 10,000 | 10,000 | 9,000 | 9,000 | 9,000 | 7,000 | 7,000 | 7,000 | 7,000 | 6,000 | |||||
additional paid-in-capital | 1,102,490,000 | 1,090,914,000 | 1,081,315,000 | 1,069,631,000 | 1,056,738,000 | 1,043,826,000 | 832,148,000 | 817,799,000 | 805,107,000 | 793,699,000 | 783,978,000 | 612,402,000 | 601,771,000 | 593,020,000 | 582,391,000 | 414,831,000 | 408,629,000 | 403,214,000 | 398,065,000 |
accumulated other comprehensive income | 65,000 | 69,000 | -92,000 | -52,000 | 84,000 | -6,000 | -22,000 | -5,000 | 67,000 | ||||||||||
accumulated deficit | -661,403,000 | -640,125,000 | -620,399,000 | -590,077,000 | -554,081,000 | -488,367,000 | -525,404,000 | -520,997,000 | -458,585,000 | -404,074,000 | -357,924,000 | -312,061,000 | -269,668,000 | -229,559,000 | -191,764,000 | -155,234,000 | -127,487,000 | -105,548,000 | -86,308,000 |
total stockholders’ equity | 441,162,000 | 450,868,000 | 460,834,000 | 479,512,000 | 502,751,000 | 555,463,000 | 306,731,000 | 296,806,000 | 346,540,000 | 389,627,000 | 426,054,000 | 300,415,000 | 332,039,000 | 363,076,000 | 390,631,000 | 259,603,000 | |||
total liabilities and stockholders' equity | 507,827,000 | 513,780,000 | 519,037,000 | 534,356,000 | 582,788,000 | 600,807,000 | 400,437,000 | 326,645,000 | 376,048,000 | 414,179,000 | 450,756,000 | 323,563,000 | 349,062,000 | 381,861,000 | 404,047,000 | 267,779,000 | |||
current portion of operating lease liability | 190,000 | ||||||||||||||||||
long-term portion of lease liabilities | 77,000 | 190,000 | 300,000 | 408,000 | 514,000 | 617,000 | |||||||||||||
accumulated other comprehensive gain | 9,000 | ||||||||||||||||||
common stock, 0.001 par value... | 9,000 | 9,000 | |||||||||||||||||
accumulated other comprehensive loss | -7,000 | -9,000 | -71,000 | -392,000 | -3,000 | ||||||||||||||
stockholders’ equity | |||||||||||||||||||
operating lease liabilities, long-term | 16,000 | 65,000 | 112,000 | ||||||||||||||||
liabilities, redeemable convertible preferred shares, redeemable convertible noncontrolling interest and stockholders’ equity/members’ | |||||||||||||||||||
redeemable convertible preferred shares, no par value; no shares authorized, issued and outstanding at december 31, 2021; 22,851,257 shares authorized, issued and outstanding at december 31, 2020 | |||||||||||||||||||
redeemable convertible noncontrolling interest | |||||||||||||||||||
stockholders’ equity/members’ | |||||||||||||||||||
preferred stock, 10,000,000 shares authorized, 0.0001 par value... | |||||||||||||||||||
common shares, no par value; no shares authorized, issued and outstanding at december 31, 2021; 28,887,127 shares authorized and 6,035,869 shares at december 31, 2020 | |||||||||||||||||||
common stock, 500,000,000 shares authorized, 0.0001 par value... | 6,000 | 6,000 | 6,000 | ||||||||||||||||
incentive shares, no par value; no shares authorized, issued and outstanding at december 31, 2021; 4,312,540 shares authorized and 4,112,017 shares issued and outstanding at december 31, 2020 | |||||||||||||||||||
total stockholders’ equity/members’ | 281,148,000 | 297,672,000 | 311,763,000 | ||||||||||||||||
total liabilities, redeemable convertible preferred shares, redeemable convertible noncontrolling interest and members’ deficit | 289,821,000 | 316,537,000 | |||||||||||||||||
redeemable convertible preferred shares, no par value; no shares authorized, issued and outstanding at september 30, 2021; 22,851,257 shares authorized, issued and outstanding at december 31, 2020 | |||||||||||||||||||
common shares, no par value; no shares authorized, issued and outstanding at september 30, 2021; 28,887,127 shares authorized and 6,035,869 shares at december 31st, 2020 | |||||||||||||||||||
incentive shares, no par value; no shares authorized, issued and outstanding at september 30, 2021; 4,312,540 shares authorized and 4,112,012 shares issued and outstanding at december 31, 2020 | |||||||||||||||||||
total liabilities, redeemable convertible preferred shares, redeemable convertible noncontrolling interest and stockholders' equity/members' | 303,783,000 | ||||||||||||||||||
redeemable convertible preferred shares, no par value; no shares authorized, issued and outstanding at june 30, 2021; 22,851,257 shares authorized, issued and outstanding at december 31, 2020 | |||||||||||||||||||
common shares, no par value; no shares authorized, issued and outstanding at june 30, 2021; 28,887,127 shares authorized and 6,035,869 shares at december 31st, 2020 | |||||||||||||||||||
incentive shares, no par value; no shares authorized, issued and outstanding at june 30, 2021; 4,312,540 shares authorized and 4,112,012 shares issued and outstanding at december 31, 2020 |
Cashflow Statements:
Quarterly
Annual
| Unit: USD | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 | 2024-06-30 | 2024-03-31 | 2023-12-31 | 2023-09-30 | 2023-06-30 | 2023-03-31 | 2022-12-31 | 2022-09-30 | 2022-06-30 | 2022-03-31 | 2021-12-31 | 2021-09-30 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cash flows from operating activities: | ||||||||||||||||||
net loss | -21,278,000 | -19,726,000 | -30,322,000 | -35,996,000 | -4,407,000 | -62,412,000 | -54,511,000 | -46,150,000 | -45,863,000 | -42,393,000 | -40,109,000 | -37,795,000 | -36,530,000 | -27,747,000 | -21,938,000 | -19,241,000 | ||
adjustments to reconcile net loss to net cash from operating activities: | ||||||||||||||||||
acquired in-process research and development assets | 0 | 0 | 0 | 0 | ||||||||||||||
share-based compensation expense | 11,068,000 | 9,561,000 | 10,898,000 | 12,861,000 | 11,035,000 | 11,554,000 | 13,030,000 | 12,644,000 | 10,811,000 | 9,606,000 | 9,477,000 | 9,447,000 | 6,833,000 | 8,576,000 | 5,631,000 | 6,202,000 | 5,097,000 | 5,149,000 |
depreciation expense | 91,000 | 90,000 | 91,000 | 94,000 | 38,000 | 16,000 | 15,000 | 23,000 | 13,000 | 11,000 | 6,000 | 6,000 | 15,000 | 36,000 | 6,000 | 6,000 | ||
accretion of discounts on short-term investments | -3,215,000 | -4,121,000 | -4,152,000 | -4,250,000 | -2,823,000 | -1,377,000 | -897,000 | -1,292,000 | -1,576,000 | -2,644,000 | -5,259,000 | -599,000 | -999,000 | |||||
amortization of intangible assets | 795,000 | 795,000 | 795,000 | 725,000 | 586,000 | 586,000 | ||||||||||||
amortization of operating right-of-use asset | 108,000 | 49,000 | 78,000 | 75,000 | 135,000 | 144,000 | ||||||||||||
loss from sale of property and equipment | 0 | 0 | ||||||||||||||||
gain from sale of priority review voucher | 0 | 0 | ||||||||||||||||
changes in operating assets and liabilities: | ||||||||||||||||||
accounts receivable | -10,038,000 | 2,972,000 | -1,615,000 | -4,178,000 | -5,181,000 | 441,000 | ||||||||||||
inventory | 772,000 | -480,000 | -2,940,000 | -212,000 | -560,000 | -2,554,000 | ||||||||||||
prepaid expenses and other current assets | 3,708,000 | 480,000 | -1,101,000 | -606,000 | -2,230,000 | 752,000 | -3,915,000 | 837,000 | -1,174,000 | -851,000 | -2,693,000 | 1,396,000 | 567,000 | 1,467,000 | -3,002,000 | 422,000 | 1,091,000 | -86,000 |
deposits and other long-term assets | 87,000 | -134,000 | 32,000 | -94,000 | -4,000 | 0 | 50,000 | 47,000 | 19,000 | 26,000 | 228,000 | -18,000 | -20,000 | 35,000 | -319,000 | 4,000 | -31,000 | -12,000 |
accounts payable | -2,045,000 | 688,000 | 2,550,000 | -722,000 | 245,000 | -3,427,000 | 1,664,000 | 2,204,000 | -815,000 | -1,174,000 | -74,000 | 4,379,000 | -3,713,000 | 3,534,000 | -262,000 | -1,043,000 | 1,059,000 | 338,000 |
accrued expenses and other current liabilities | 6,405,000 | 4,079,000 | 490,000 | -26,984,000 | 33,436,000 | -51,883,000 | 62,313,000 | -1,765,000 | 5,877,000 | 1,128,000 | 1,759,000 | 1,810,000 | 2,114,000 | 1,903,000 | 4,629,000 | 595,000 | 1,549,000 | 1,628,000 |
deferred revenue | -230,000 | 52,000 | 232,000 | 199,000 | 264,000 | |||||||||||||
operating lease liability | -100,000 | -110,000 | 87,000 | 91,000 | 4,000 | -59,000 | ||||||||||||
other long-term liability | ||||||||||||||||||
net cash from operating activities | -14,149,000 | -5,805,000 | -24,806,000 | -58,997,000 | -30,008,000 | 50,753,000 | -49,129,000 | -49,729,000 | -41,372,000 | -37,064,000 | -42,432,000 | -25,985,000 | -35,310,000 | -23,214,000 | -29,787,000 | -21,563,000 | -13,169,000 | -12,221,000 |
capital expenditures | 0 | 0 | -3,000 | -317,000 | -1,419,000 | -724,000 | 0 | -8,000 | -41,000 | -149,000 | 6,000 | 0 | 0 | 0 | 0 | 0 | 0 | |
free cash flows | -14,149,000 | -5,805,000 | -24,809,000 | -59,314,000 | -31,427,000 | 50,029,000 | -49,129,000 | -41,380,000 | -37,105,000 | -42,581,000 | -25,979,000 | -35,310,000 | -23,214,000 | -29,787,000 | -21,563,000 | -13,169,000 | -12,221,000 | |
cash flows from investing activities: | ||||||||||||||||||
cash paid for purchase of short-term investments | -57,948,000 | -209,565,000 | -238,502,000 | -189,796,000 | -275,221,000 | -214,634,000 | -121,599,000 | -47,162,000 | -99,137,000 | -79,957,000 | -104,730,000 | -160,014,000 | -121,368,000 | -266,848,000 | ||||
proceeds from maturity of short-term investments | 215,453,000 | 223,025,000 | 264,795,000 | 161,000,000 | 7,000,000 | 123,250,000 | 47,782,000 | 136,450,000 | 171,915,000 | 125,153,000 | 148,847,000 | |||||||
proceeds from sale of short-term investments | 0 | |||||||||||||||||
cash paid for acquired intangible assets | 0 | 0 | 0 | -3,500,000 | 0 | 0 | ||||||||||||
proceeds from sale of priority review voucher | 0 | 0 | ||||||||||||||||
cash paid for acquired in-process research and development assets | 0 | 0 | 0 | 0 | ||||||||||||||
cash paid for purchase of property and equipment | 0 | 0 | -3,000 | -317,000 | -1,419,000 | -724,000 | -8,000 | -41,000 | -149,000 | -26,000 | 0 | |||||||
proceeds from sale of property and equipment | 0 | 0 | ||||||||||||||||
net cash provided (used in) by investing activities | ||||||||||||||||||
cash flows from financing activities: | ||||||||||||||||||
proceeds from issuance of common stock in connection with private placement, net of placement agent fees and offering costs | 0 | |||||||||||||||||
proceeds from issuance of prefunded warrants to purchase common stock in connection with private placement, net of issuance costs | 0 | |||||||||||||||||
proceeds from issuance of common stock | 0 | 0 | 0 | 0 | 0 | -615,000 | ||||||||||||
proceeds from issuance of common stock upon stock option exercises | 918,000 | 977,000 | 324,000 | 48,000 | 0 | 115,000 | 39,000 | 1,184,000 | 1,596,000 | |||||||||
proceeds from issuance of common stock upon employee stock purchase plan purchase | 345,000 | 0 | 933,000 | 0 | 0 | |||||||||||||
cash from financing activities | 471,000 | 0 | 1,851,000 | 200,095,000 | 1,297,000 | 48,000 | 115,000 | 162,101,000 | 1,184,000 | |||||||||
net increase in cash and cash equivalents | 153,801,000 | 7,655,000 | 2,264,000 | -91,610,000 | -297,797,000 | 183,149,000 | -30,775,000 | 39,607,000 | -10,395,000 | 51,968,000 | -35,602,000 | -268,013,000 | 126,146,000 | -21,578,000 | -12,851,000 | -12,836,000 | ||
cash and cash equivalents, beginning of period | 0 | 0 | 0 | 124,968,000 | 0 | 0 | 0 | 230,784,000 | 0 | 0 | 0 | 85,262,000 | 0 | 0 | 0 | 284,309,000 | 0 | 0 |
cash and cash equivalents, end of period | 153,801,000 | 7,655,000 | 2,264,000 | 33,358,000 | -297,797,000 | 183,149,000 | -30,775,000 | 270,391,000 | -10,395,000 | 51,968,000 | 139,943,000 | 49,268,000 | -35,602,000 | -268,013,000 | 126,146,000 | 262,731,000 | -12,851,000 | -12,836,000 |
supplemental disclosure of cash flow information: | ||||||||||||||||||
income taxes paid | -567,000 | 0 | 1,015,000 | |||||||||||||||
supplemental disclosures of noncash activities: | ||||||||||||||||||
cash not yet paid for acquired intangible asset | 0 | 0 | 0 | 2,000,000 | ||||||||||||||
right-of-use asset obtained in exchange for new operating lease liabilities | 0 | 0 | 0 | 230,000 | 0 | |||||||||||||
cash not yet paid for license agreement milestone payment | ||||||||||||||||||
net cash from investing activities | 13,460,000 | 26,322,000 | -32,613,000 | -269,640,000 | -67,699,000 | 17,057,000 | 89,288,000 | 88,917,000 | 20,274,000 | -11,193,000 | -2,210,000 | |||||||
deferred offering costs not yet paid | ||||||||||||||||||
cash not yet paid for upfront license agreement payment | ||||||||||||||||||
net income | ||||||||||||||||||
purchases of property and equipment included in accrued expenses and other current liabilities | ||||||||||||||||||
unpaid/deferred offering costs | ||||||||||||||||||
amortization of operating right-of-use assets | 93,000 | 90,000 | 88,000 | 86,000 | 83,000 | 165,000 | 129,000 | 127,000 | 47,000 | 46,000 | 45,000 | |||||||
operating lease liabilities | -108,000 | -106,000 | -104,000 | -99,000 | -96,000 | -163,000 | -68,000 | -67,000 | -49,000 | -28,000 | -52,000 | |||||||
cash flows from operating activities | ||||||||||||||||||
cash flows from investing activities | ||||||||||||||||||
proceeds from maturity of short-term investment | ||||||||||||||||||
net cash from (used) in investing activities | ||||||||||||||||||
cash flows from financing activities | ||||||||||||||||||
proceeds from issuance of series b redeemable convertible preferred shares, net of issuance costs | 0 | 0 | ||||||||||||||||
proceeds from issuance of common stock upon espp purchase | 322,000 | 0 | ||||||||||||||||
net cash from financing activities | 318,000 | -615,000 | ||||||||||||||||
supplemental disclosures of noncash activities | ||||||||||||||||||
lease liability obtained in exchange for right-of-use asset | 0 | 0 | ||||||||||||||||
exchange of 45,331,483 preferred, common, and incentive shares in connection with the conversion | 0 | 0 | ||||||||||||||||
exchange of redeemable convertible noncontrolling interest to 6,470,382 shares of common stock | 0 | 0 | ||||||||||||||||
net decrease in cash and cash equivalents | -35,994,000 | |||||||||||||||||
purchases of property and equipment included in accounts payable and in accrued expenses and other current liabilities | 32,000 | |||||||||||||||||
non-cash interest expense | 5,000 | |||||||||||||||||
changes in derivative tranche liabilities | ||||||||||||||||||
proceeds from issuance of series a redeemable convertible preferred shares, net of issuance costs | ||||||||||||||||||
transfers to redeemable convertible noncontrolling interest | ||||||||||||||||||
cash paid for property and equipment | ||||||||||||||||||
cash from investing activities | -5,997,000 | -15,000 | 0 | 0 | ||||||||||||||
property and equipment expenditures | -15,000 | |||||||||||||||||
payments of financing issuance costs | ||||||||||||||||||
depreciation and amortization expense | 5,000 | 5,000 | ||||||||||||||||
issuance of shares for research and development | ||||||||||||||||||
purchases of property and equipment | ||||||||||||||||||
proceeds from issuance of convertible notes | ||||||||||||||||||
recognition of contingent beneficial conversion feature upon notes conversion | ||||||||||||||||||
issuance of series a redeemable convertible shares for research and development | ||||||||||||||||||
conversion of convertible notes and accrued interest into series a redeemable convertible preferred shares | ||||||||||||||||||
issuance of derivative tranches liability | ||||||||||||||||||
right of use asset capitalization |