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Unit: USD	2025-09-30	2025-06-30	2025-03-31	2024-12-31	2024-09-30	2024-06-30	2024-03-31	2023-12-31	2023-09-30	2023-06-30	2023-03-31	2022-12-31	2022-09-30	2022-06-30	2022-03-31	2021-12-31	2021-09-30	2021-06-30	2021-03-31	2020-12-31	2020-09-30	2020-06-30	2020-03-31	2019-12-31	2019-09-30	2019-06-30	2019-03-31	2018-12-31	2018-09-30	2018-06-30	2018-03-31	2017-12-31	2017-09-30	2017-06-30	2017-03-31	2016-12-31	2016-09-30	2016-06-30	2016-03-31	2015-12-31	2015-09-30	2015-06-30	2015-03-31	2014-12-31	2014-09-30	2014-06-30	2014-03-31	2013-12-31	2013-09-30	2013-06-30	2013-03-31	2012-12-31	2012-09-30	2012-06-30	2012-03-31	2011-12-31	2011-09-30	2011-06-30	2011-03-31	2010-12-31	2010-09-30	2010-06-30	2010-03-31	2009-12-31	2009-09-30	2009-06-30	2009-03-31	2008-01-04	2007-01-04

operating activities:
net income	52,783,000	52,108,000	56,737,000	55,936,000	43,884,000	40,794,000	23,275,000	34,844,000	-30,764,000	37,762,000	29,568,000	25,471,000	22,748,000	21,619,000	13,241,000	9,309,000	10,329,000	12,181,000	7,663,000	11,437,131	43,339,867	9,779,987	10,426,015	7,929,713	13,630,179	10,959,948	-644,503	-14,499,609	-7,838,873	-5,965,140	-5,699,892	-5,387,698	-4,177,649	-3,879,901	-4,967,129	-4,163,320	-3,953,981	-4,568,914	-5,386,237	-5,815,158	-4,449,038	-4,558,503	-5,410,259	-3,490,030	-5,009,892	-3,198,020	-3,811,119	-1,354,658	-5,912,059	-3,143,590	-1,744,289	-76,585	-2,621,535	-289,080	-1,089,186	-2,351,934	-1,127,841	-1,394,151	-1,517,136	-728,754	-903,985	-1,328,541	-1,045,043	-1,162,120	-1,286,720	-1,761,887	-3,031,201	-1,584,047	-2,151,280
adjustments to reconcile net income to net cash from operating activities:
depreciation	72,000	116,000	115,000	114,000	106,000	91,000	86,000	84,000	81,000	82,000	69,000	35,000	35,000	37,000	34,000	33,000	31,000	31,000	97,000	19,319	29,793	29,412	13,541	27,609	6,532	6,438	13,748	12,493	9,294	8,176	8,015	6,935	12,839	12,957	12,958	11,964	9,482	8,762	13,198	6,086	11,259	8,975	8,148	7,971	7,235												7,452	21,030	6,438		6,234	6,329	6,751		7,306	7,799	8,040	8,207
stock-based compensation	5,670,000	7,597,000	5,850,000	5,171,000	4,424,000	4,408,000	8,248,000	4,250,000	3,810,000	3,298,000	2,892,000	1,926,000	2,055,000	2,023,000	1,903,000	1,472,000	1,512,000	1,518,000	1,571,000	1,469,264	1,477,846	1,794,462	1,519,351	1,149,348	817,060	924,996	933,411	1,029,621	758,176	791,507	971,340	485,510	529,738	638,569	754,144	488,645	532,202	357,269	457,969	576,342	330,770	363,895	314,451	287,643	444,626	22,570	23,130	42,550	46,665	44,888	41,752	204,274	45,585	45,090	45,090	248,923	48,985	65,076	53,751	245,982	35,972	85,788	82,347	319,277	75,355	64,532	142,274	263,404	-513,600
amortization of intangible assets	9,344,000	9,344,000	9,345,000	9,344,000	9,345,000	9,344,000	9,344,000	9,059,000	8,487,000	8,488,000	6,531,000	580,000
deferred taxes	2,417,000	-2,434,000	-2,321,000	2,555,000	-8,584,000	-1,613,000	-1,746,000	883,000	-13,943,000	-3,239,000	-1,519,000	1,285,000	934,000	817,000	1,901,000	2,745,000	2,301,000	2,720,000	1,550,000	-1,623,822
accretion of discount	-96,000	-78,000	-60,000	-39,000	-1,083,000	134,000	153,000	174,000
reduction in the carrying amount of right-of-use asset	74,000	74,000	72,000	71,000	70,000	69,000	68,000	67,000	66,000	65,000	64,000	63,000	62,000	62,000	60,000	76,000	108,000
change in fair value of equity securities	2,089,000	2,952,000	-2,644,000	-6,722,000	-1,759,000	2,262,000	1,144,000	-3,592,000
inventory reserve and write-offs	-292,000
increase in:
accounts receivable	-40,546,000	5,402,000	-5,789,000	-7,210,000	-1,094,000	3,321,000	-6,979,000	-5,465,000	-5,253,000	-9,394,000	-22,963,000	-1,102,000	250,000	965,000	-3,933,000	6,000	-333,000	-691,000	386,000	-115,533	890,369	156,301	3,618,434	-441,645	281,075	-3,125,046	-7,251,381
inventory	-9,087,000	455,000	-237,000	476,000	-2,003,000	1,939,000	-4,309,000	-6,609,000	1,716,000	-423,000	577,000	327,000	718,000	-23,000	43,000	-920,000	147,000	-2,707,000	261,000	96,938	-2,919,614	383,414	-254,546	-1,356,991	-329,922	-173,292	-40,575
prepaid expenses and other current assets	-6,697,000	-7,407,000	7,020,000	-2,655,000	5,166,000	-9,805,000	-1,210,000	1,427,000	-5,328,000	-1,700,000	-191,000
accounts payable	3,568,000	-5,669,000	-5,396,000	5,030,000	4,447,000	-3,145,000	-4,534,000	10,197,000	177,000	1,030,000	-584,000	1,446,000	214,000	-2,824,000	2,371,000	16,000	-172,000	365,000	-1,697,000	2,250,680	-3,799,438	4,457,201	-2,769,870	-29,582	818,303	388,640	602,719	996,383	418,391	117,570	-1,140,552	863,967	389,263	-225,583	-15,248	-122,148	348,032	-544,181	-542,654	977,106	-499,271	265,777	-763,695	1,289,415	-713,381	306,071	81,316	-622,552	1,025,059	-118,903	-798,478	1,009,754	132,926	-127,346	86,395
accrued expenses and other liabilities	13,241,000	8,265,000	-2,552,000	8,900,000	20,046,000	16,428,000	8,474,000	8,190,000	5,163,000	-5,131,000	-2,422,000	11,506,000	9,022,000	2,367,000	-6,504,000	6,436,000	4,574,000	1,548,000	-7,038,000	2,359,449	1,904,346	-1,773,557	-3,699,518	6,139,918	3,006,526	4,730,908	-1,337,155	5,036,555	-10,539	226,004	-401,277	664,671	501,902	154,996	-178,917	217,155	-660,831	183,412	-219,984	124,718	317,468	-63,231	755,984	-1,367,588	4,286,965	-385,354	214,681	-250,409	348,316	772,728	134,436	-116,826	-56,357	-74,744	-28,578
operating lease liability	-102,000	-100,000	-97,000	-94,000	-94,000	-92,000	-89,000	-86,000	-86,000	-84,000	-82,000	-78,000	-79,000	-77,000	-73,000	-78,000	0	0	942,000	-85,791	-83,334	-677,203	-72,952	-72,083	-69,601	-67,968	-67,155
net cash from operating activities	32,438,000	71,298,000	60,043,000	70,877,000	72,871,000	64,135,000	31,925,000	55,648,000	45,128,000	30,754,000	12,070,000	40,077,000	41,301,000	26,191,000	8,478,000	19,176,000	21,707,000	15,675,000	3,814,000	13,105,567	11,451,109	13,265,110	7,213,078	12,291,441	16,262,617	14,020,170	-7,962,755	-8,313,530	-6,803,030	-4,506,396	-6,081,450	-4,029,867	-2,632,841	-3,200,989	-3,878,875	-4,411,739	-3,278,026	-4,343,520	-5,930,218	-4,631,322	-5,343,193	-4,245,737	-3,794,969	-3,979,955	-3,552,924	-2,983,860	-2,425,044	-4,130,259	-1,683,987	-1,812,224	-2,249,204	-1,593,786	-1,100,934	-1,144,355	-1,301,291	-1,438,196	-1,252,640	-1,463,094	-831,119	-769,152	-817,344	-1,149,321	-1,021,588	-828,906	-1,353,231	-2,664,440	-2,836,612	-1,224,029	-3,924,053
investing activities:
purchases of property and equipment	0			-88,000	-259,000	-10,000	-199,000	-93,000	-64,000	0	-74,000	0	0			-41,000	-68,000	-1,000	-911,000	0				1	0	-13,737	-5,633	-56,825	-23,256
net cash from investing activities	0			-88,000	-259,000	-10,000	-199,000	-38,318,000	-92,817,000	0	-162,367,000	0	-132,000			-41,000	-68,000	-4,001,000	-6,911,000	0	-10,011,398	0	5,000,000	31,658,771	5,047,027	-9,876,922	10,395,719	14,105,118	7,426,872	-5,210,308	-31,847,693	60,790	-29,838	-1,765	-33,145	586,452	2,199,022	832,662	-65,571	50,477	-44,418	30,711	-43,269	-8,943	15,057	-10,012,191	1,265,047	-6,806,550	-4,197,316	2,021,755	1,485,310	-14,052,769	-1	-1,900	-4,981	2,001,887	-2,019											-1,345	-45,996
financing activities:
payment of employee withholding tax related to stock-based compensation	0	-219,000	-642,000	-464,000	0	0	-204,000	-453,000	0	-52,000	-477,000	-210,000	0			-136,000	0			-39,163								0	0							0	0	0	-11,265
proceeds from exercise of stock options	5,796,000	2,210,000	4,787,000	5,984,000	3,978,000	2,031,000	1,522,000	693,000	212,000	617,000	1,270,000	3,201,000	3,984,000	1,384,000	1,000,000	685,000	2,955,000	271,000	188,000	64,732	631,048	36,201	26,149	578,280	256,062	192,550	89,350	151,499	104,532	8,500	33,032
payment of liabilities arising from asset acquisition	-1,142,000	-1,119,000	-1,085,000	-1,087,000	-9,952,000	-874,000	-973,000	-905,000	-10,339,000	-779,000	-644,000
proceeds from issuance of common stock				0	0	0	141,000,000																																		0	0	34,873,869														0	0	2,228,634	0
payment of fees in connection with issuance of common stock				0	0	0	-296,000
net cash from financing activities	4,654,000	872,000	3,060,000	4,433,000	-5,974,000	1,157,000	141,049,000	-665,000	-10,127,000	-214,000	149,000	2,253,000	3,984,000	-2,992,000	-1,551,000	-2,526,000	-2,098,000	-3,707,000	188,000	25,569	614,014	36,201	26,149	578,280	256,062	192,550	89,350	151,499	104,532	4,052	33,032	54,136,795	1,407,936			80,251	0	0	-11,265	65,402	916,617	113,044	36,064,895	1,821,999	0	26,725,130	16,504	189,801	17,965,193			5,082,634	5,559,952			3,313,944	0	0	2,228,634	0								-2,010
net increase in cash and cash equivalents	37,092,000	72,144,000	63,103,000	75,222,000	66,638,000	65,282,000	172,775,000	16,665,000	-57,816,000	30,540,000	-150,148,000	42,330,000	45,153,000	32,540,000	6,927,000	16,609,000	19,541,000	7,967,000	-2,909,000	13,131,136	2,053,725	13,301,311	12,239,227	44,528,492	21,565,706	4,335,798	2,522,314	5,943,087	728,374	-9,712,652	-37,896,111	50,167,718	-1,254,743	-1,397,317	-3,912,020	-3,745,036	-1,079,004	-3,510,858	-6,007,054								-1,143,493
cash and cash equivalents – beginning of period	0	0	517,553,000	0	0	0	137,636,000	0	0	0	298,395,000	0	0	0	171,445,000													0				0
cash and cash equivalents – end of period	37,092,000	72,144,000	580,656,000	75,222,000	66,638,000	65,282,000	310,411,000	16,665,000	-57,816,000	30,540,000	148,247,000	42,330,000	45,153,000	32,540,000	178,372,000													5,943,087				50,167,718
supplemental disclosures of cash flow information:
cash paid for income taxes	15,895,000	38,601,000	639,000	16,760,000	17,590,000			8,795,000	13,842,000			1,323,000	500,000	5,803,000	41,000	1,562,000	1,097,000			590,497	2,145,500
cash paid for interest	121,000	112,000	103,000	94,000	1,161,000	75,000	65,000	55,000
realized loss on sale of available-for-sale securities												0	129,000
acquired research and development inventory expensed from asset acquisition												0
acquired inventory samples expensed from asset acquisition								0	0	0	130,000
acquired in-process research and development								2,225,000
proceeds from sale of available-for-sale securities													9,868,000
payments in connection with asset acquisitions								-36,000,000
acquisition of in-process research and development								-2,225,000
purchase of equity securities								0
repurchase of common stock												0	0	-4,356,000	-2,551,000	-3,075,000	-5,053,000
non-cash investing and financing activities:
liabilities arising from asset acquisition								0	0	0	1,915,000	0
payment in connection with asset acquisition										0	-162,293,000
purchases of investments																0	0	-4,000,000	-6,000,000	0				0	-4,952,973	-19,827,454	-9,944,974	339,550	-95,904
operating lease liabilities arising from obtaining right-of-use assets																0	0	0	3,309,000
change in accrued interest and accretion of discount on investments												0	8,000	11,000	-2,000	4,000	-3,000	0	-6,000	-516	-8,029	-84,942	81,296	-105,269	-107,989
proceeds from exercise of stock options not yet settled at end of period															102,000
prepaid expenses and other current assets and deposits												-1,382,000	557,000	581,000	-563,000	77,000	3,213,000	602,000	85,000	-2,713,719	1,907,201	-1,458,538	-1,711,641	-1,011,675	-1,850,796	392,663	-231,485	-832,961	-139,479	315,487	180,916	-663,252	111,066	308,304	118,082	-737,089	340,122	372,915	480,846	-110,820	-532,650	71,306	120,124	-235,340
proceeds from maturities and sale of available-for-sale securities
payment in connection with license agreement												0
repurchase of common stock not yet settled at end of period																			293,000
proceeds from maturities and sales of investments																				0	0	0	5,000,000
cash and cash equivalents—beginning of period																	0	0	130,237,000		0	0	89,511,710
cash and cash equivalents—end of period																	19,541,000	7,967,000	127,328,000		2,053,725	13,301,311	101,750,937
unrealized gain on available-for-sale securities																	-26,000	8,000	-76,000	37,803	-5,280	-84,942	74,246	-9,923	-2,330	28,446	13,560	25,700	-9,450
amortization of right-of-use asset																				12,167	59,544	658,573	62,968
non-cash change in right-of-use asset																									61,250	60,430	59,621
proceeds from sales/maturities of investments																									10,000,000	9,964,269	20,346,326
cash and cash equivalents - beginning of period																									0	0	16,559,400			0	57,496,702			0	13,893,064		0	0	28,235,016
cash and cash equivalents - end of period																									21,565,706	4,335,798	19,081,714			-9,712,652	19,600,591			-1,397,317	9,981,044		-1,079,004	-3,510,858	22,227,962
change in fair value of warrants liability																																0	0	-210,331	397,235	-106,946	106,948	-152,783	-733,356	-389,596	-521,731	-333,956	1,180,278	-472,026	906,787	223,591	335,514	-1,330,155	2,676,601	498,587	45,326	-1,419,218	1,340,566	-776,919	-274,207
proceeds from maturities of investments																												13,822,393
proceeds from exercise of warrants																																0	1,403,986							0	591,668	113,044	1,191,026	1,299,999	0	0	16,504	189,801
exercise of liability classified warrants for common stock																																0	0							0	1,059,348	251,305	410,870	0	0	0	18,537	394,484
purchase of investments																															-31,847,693
non-cash investing activities:
unrealized loss on available-for-sale securities																															21,826
capital expenditures																																				-7,130	-2			0	-14,425	-1,130	-7,910	-13,896	-13,119	-13,002	-17,306	0	0	1	-9,433	-45,500	-1	-1,900	-4,981	-1,820	0											-1,345	-45,996
free cash flows																																				-4,418,869	-3,278,028			-4,631,322	-5,357,618	-4,246,867	-3,802,879	-3,993,851	-3,566,043	-2,996,862	-2,442,350	-4,130,259	-1,683,987	-1,812,223	-2,258,637	-1,639,286	-1,100,935	-1,146,255	-1,306,272	-1,440,016	-1,252,640											-1,225,374	-3,970,049
proceeds (purchase) of short-term investments
proceeds (purchase) of certificates of deposit																																				568,031	2,199,915										298,615
payment of employee withholding tax related to stock- based compensation
proceeds from exercise of options																																								65,402				522,000				0	0
non-cash incentive received from lessor																																								0
purchase of short-term investments																																	-29,838	-1,765	-33,145		-891	-28,062	-65,201					5,702							-2,702
supplemental disclosures of non-cash investing and financing activity
purchase of certificates of deposit																																							-370
proceeds from issuance of common stock and warrants																																												0	0			0				66,385	5,559,952
decrease (increase) in:
(purchase) redemption of certificates of deposit
net increase in cash																																									-4,470,994	-4,101,982	32,226,657		-3,537,867				12,083,890	233,031	-763,894		4,459,017	2,792,048	-1,306,272		-1,254,659	-3,466,582	1,397,515		638,809	-1,149,321	-1,021,588		-1,353,231	-2,664,440	-2,836,612	-1,227,384
cash and cash equivalents at beginning of period																																									0	0	9,096,778		0	0	2,215,958		0	0	1,409,939		0	0	6,029,067		0	0	5,475,158		0	0	7,779,277		0	0	11,766,629	15,943,896
cash and cash equivalents at end of period																																									-4,470,994	-4,101,982	41,323,435		-3,537,867	13,729,079	1,072,465		12,083,890	233,031	646,045		4,459,017	2,792,048	4,722,795		-1,254,659	-3,466,582	6,872,673		638,809	-1,149,321	6,757,689		-1,353,231	-2,664,440	8,930,017	14,716,512
redemption (purchase) of short-term investments																																										32,305	-34,807
redemption (purchase) of certificates of deposit																																										-464	-552
proceeds from issuance of convertible promissory note
conversion of note to common stock
proceeds from certificates of deposit																																													-749
prepaid expenses and deposits																																														41,199	726,149	-620,741	125,724	128,360	66,685	-1,197,838	55,156	75,934	-43,606
proceeds from (purchase of) short-term investments
supplemental disclosures of non-cash financing activity
depreciation and amortization																																															5,285	5,706	5,707	5,706	5,364	2,653	2,725	2,710	2,801
proceeds (purchase) of short term investments																																															983,738
proceeds from issuance of preferred stock
payment of employee withholding tax related to restricted stock units
non-cash investing and financing activity
conversion of note for common stock
government grant receivable
purchase of short term investments
proceeds from (purchase of) certificates of deposit																																																	-1,855	997,075	1,497,445
proceeds from (purchase of) short term investments
purchase of certificates of deposits
supplemental disclosures of non-cash operating activity
reconciliation of net income to net cash from operating activities:
interest receivable
changes in assets and liabilities:
decrease in government grant receivable																																																									0	0	134,025
decrease (increase) in prepaid expenses and deposits																																																									52,246				128,161				42,903
increase in accounts payable																																																									-303,973	52,592	319,486	-135,338	-10,698	163,705	-161,371	86,568	-112,596	-461,963	404,919	96,712	-578,207
increase in accrued expenses and other liabilities																																																									70,491	-269,531	234,052	34,210	-73,028	-46,556	194,263	-53,336	-79,479	-607,019	-301,325	35,257
purchase of certificate of deposit																																																									-2,019
payment of employee withholding tax related to rsu
change in assets and liabilities:
payment of employee withholding tax related to rsus																																																																				-2,010
supplemental disclosure of non-cash operating activity:
increase in prepaid expenses and deposits																																																											-61,735				-98,535				-68,781
decrease in interest receivable																																																																0	0
increase in grant funds receivable
decrease (increase) in other prepaid expenses and deposits
payment of shelf registration costs
decrease (increase) in interest receivable																																																																			9,462	22,542
change in assets and liabilities
(increase) in other prepaid expenses and deposits																																																																				-66,104
supplemental disclosure of non-cash investing and financing activities:
increase in accrued expenses																																																																					-251,406
cash and cash equivalents — beginning of period
cash and cash equivalents — end of period
change in assets and liabilities (increase) in other prepaid expenses and deposits
prepaid expenses for initial public offering
cash paid during the year for interest
cash paid during the year for income taxes
non-cash financing activities:

The information provided in this report is taken from www.sec.gov and many other data providers. While we have conducted our best efforts to ensure that the parsed data is accurate, we cannot guarantee its accuracy. Please use caution and understand that any consequences of its use are your own responsibility.