7Baggers
Quarterly
Annual
    Unit: USD2023-12-31 2023-09-30 2023-06-30 2023-03-31 2022-12-31 2022-09-30 2022-06-30 2022-03-31 2021-12-31 2021-09-30 2021-06-30 2021-03-31 2020-12-31 2020-09-30 2020-06-30 2020-03-31 2019-12-31 2019-09-30 2019-06-30 2019-03-31 2018-12-31 2018-09-30 2018-06-30 2018-03-31 2017-12-31 2017-09-30 2017-06-30 2017-03-31 2016-12-31 2016-09-30 2016-06-30 2016-03-31 2015-12-31 2015-09-30 2015-06-30 2015-03-31 2014-12-31 2014-09-30 2014-06-30 2014-03-31 2013-12-31 
      
                                             
      operating activities
                                             
      net income
    -41,902,000 -33,882,000 -808,000 -28,778,000 -26,633,000 -24,505,000 -27,094,000 -27,769,000 -26,543,000 -22,682,000 -23,222,000 -17,551,000 35,184,014 -11,421,000 -10,726,000 -13,088,000 73,292,192 -26,282,000 -24,038,000 -23,075,000 -19,449,000 -18,563,000 -17,531,000 -17,005,000 -5,043,000 -8,234,000 -8,929,000 -5,351,000 -6,952,000 -5,879,000 -6,992,000 -6,848,000 -5,979,000 -5,865,000 -1,357,000 -2,328,000 -12,722,000 -5,961,000 -3,172,000 -10,062,000 -3,914,000 
      adjustments to reconcile net income to net cash from operating activities:
                                             
      depreciation and amortization
    56,000 215,000 211,000 199,000 185,000 182,000 174,000 169,000 173,000 176,000 175,000 164,000 -467,368 159,000 156,000 153,000 -421,428 144,000 140,000 138,000 66,000 14,000 13,000 12,000 9,000 8,000 9,000 9,000 8,000 10,000 6,000 5,000 5,000 6,000 5,000 6,000 5,000 5,000 5,000 3,000 5,000 
      non-cash lease expense
                                             
      stock-based compensation expense
    4,669,000 3,724,000 3,350,000 3,487,000 2,361,000 2,350,000 2,392,000 2,414,000 2,385,000 2,549,000 2,557,000 2,505,000 -5,505,865 2,552,000 963,000 1,998,000 -7,473,442 2,865,000 2,276,000 2,342,000 1,738,000 1,728,000 1,751,000 1,796,000 982,000 820,000 1,840,000 1,278,000              
      accretion of development financing liability
    5,081,000 4,843,000 4,618,000 4,403,000 4,075,000 3,819,000 3,648,000 3,365,000 2,061,000                                 
      write-off of deferred financing costs
                                           
      net amortization of investments in marketable securities
    -2,462,000 -2,094,000                                        
      changes in assets and liabilities:
                                             
      prepaid expenses and other current assets
    -746,000 745,000 -3,191,000 -3,767,000                                      
      other assets
    80,000 -1,025,000 -121,000 1,176,000 224,000 -107,000 -578,000 -728,000 1,000 -274,000 -1,000 -1,239,000     -1,016,880 -531,000 392,000 1,158,000 -917,000 -383,000 -346,000 170,000      -53,000 20,000 227,000 -171,000 -42,000 38,000 408,000 -232,000 -211,000  
      accounts payable
    1,097,000 -1,858,000 2,956,000 537,000 617,000 -387,000 667,000 -2,341,000 1,797,000 -286,000 -577,000 1,375,000 1,553,728 471,000 -737,000 -1,290,000 479,530 -1,388,000 472,000 437,000 344,000 293,000 -702,000 727,000 227,000 -17,000 5,000 197,000 -36,000 -337,000 -505,000 769,000 301,000 -1,014,000 194,000 -558,000 1,038,000 -215,000 193,000 372,000 -342,000 
      deferred collaboration revenue
    57,000 -31,001,000 33,733,000                                      
      accrued research and development expenses
    -202,000 997,000 -727,000 -965,000 -92,000 -406,000 -2,631,000 -93,000                                  
      other accrued liabilities
    6,677,000 2,190,000 1,266,000 -2,276,000 1,977,000 828,000 322,000 -1,587,000                                  
      net cash from operating activities
    -27,380,000 -26,145,000 -25,437,000 6,431,000  -17,522,000 -22,440,000 -25,362,000 -14,243,000 -15,413,000 -19,214,000 -20,561,000 29,864,275 -7,452,000 -7,749,000 -14,708,000 69,677,089 -23,127,000 -24,254,000 -22,394,000 -19,595,000 -16,077,000 -12,823,000 -6,441,000 -6,072,000 -5,466,000 -5,891,000 -2,203,000 -5,402,000 -5,741,000 -6,070,000 -6,140,000 -5,196,000 -6,660,000 -5,309,000 -6,159,000 -7,472,000 -3,892,000 -4,739,000 -5,011,000 -3,537,000 
      capex
    -180,000 -70,000 -195,000  -11,000 7,000 -94,000 20,979 288,685 -20,000 -91,000 -178,000 -469,000 -14,000 -46,000 -5,000 -10,000 -61,000 -32,000 
      free cash flows
    -27,560,000 -26,145,000 -25,507,000 6,236,000  -17,533,000 -22,440,000 -25,362,000 -14,243,000 -15,413,000 -19,207,000 -20,655,000 29,885,254 -7,452,000 -7,749,000 -14,708,000 69,965,774 -23,147,000 -24,345,000 -22,572,000 -20,064,000 -16,091,000 -12,823,000 -6,487,000 -6,072,000 -5,466,000 -5,891,000 -2,203,000 -5,402,000 -5,746,000 -6,070,000 -6,140,000 -5,196,000 -6,660,000 -5,309,000 -6,159,000 -7,472,000 -3,902,000 -4,800,000 -5,043,000 -3,537,000 
      investing activities
                                             
      purchases of property and equipment
    -180,000 -70,000 -195,000 -13,000 -11,000   7,000 -94,000 20,979    288,685 -20,000 -91,000 -178,000 -469,000 -14,000 -46,000     -5,000       -10,000 -61,000 -32,000  
      purchases of marketable securities
    -115,928,000 -29,538,000 -39,111,000 -121,097,000 -12,631,000 -46,883,000 -52,978,000 -62,485,000 -33,477,000 -10,787,000 -15,608,000 -18,212,000 153,774,700 -88,447,000 -1,000 -65,503,000 245,889,107 -24,902,000 -130,381,000 -90,897,000 -26,960,000 -63,497,000 -60,982,000 -124,943,000 -9,444,000 -79,119,000 -698,000 -9,124,000 -3,602,000 -1,600,000 -16,704,000 -1,000,000 -1,016,000 -28,397,000 -6,758,000 -6,617,000 -2,552,000 -13,590,000    
      proceeds from maturities of marketable securities
    74,001,000 44,999,000 39,900,000 60,650,000 21,000,000 42,345,000 54,300,000 11,495,000 9,400,000 39,080,000 24,280,000 54,000,000 -206,053,722 47,142,000 47,000,000 112,136,000 -198,628,119 63,430,000 57,400,000 78,051,000 54,200,000 75,118,000 58,148,000 35,334,000 14,569,000 7,215,000 3,200,000 5,900,000 13,420,000 2,000,000            
      net cash from investing activities
    -42,107,000 15,461,000   8,356,000 -4,549,000 1,198,000 -50,990,000 -24,077,000 28,293,000 8,679,000 35,694,000 -52,258,043 -41,326,000 46,999,000 46,633,000 43,573,653 38,508,000 -73,072,000 -9,044,000 26,771,000 11,607,000 -2,834,000 -89,655,000 5,098,000 -71,904,000 2,502,000 -3,224,000 9,818,000 395,000 -2,716,000 19,631,000 6,211,000 -24,947,000 6,554,000 1,099,000 2,898,000 -10,782,000 -9,604,000 550,000 -6,681,000 
      financing activities
                                             
      proceeds from issuance of common stock pursuant to equity award plans
    3,173,000 5,699,000 1,050,000 710,000    14,000 99,000   -6,908   -103,614 7,000 97,000 24,000 26,000 245,000 3,276,000 1,749,000                 
      proceeds from issuance of common stock and pre-funded warrants, net of issuance costs
    -444,000 243,224,000 92,360,000                                      
      proceeds from development financing, net of transaction costs
           24,650,000                                 
      net cash from financing activities
    2,729,000 248,923,000 1,050,000 93,070,000 9,000 24,541,000 95,163,000        -107,741,868 -167,000 108,017,000 24,000 1,539,000 -5,198,000 138,623,000 1,019,000 90,870,000 -775,000 8,605,000 -742,000    26,596,000 -384,000 4,315,000 -196,000 23,028,000 3,000 2,402,000 2,539,000 
      net increase in cash, cash equivalents and restricted cash
                                             
      cash, cash equivalents, and restricted cash at beginning of period
                                             
      cash, cash equivalents, and restricted cash at end of period
                                             
      supplemental disclosures:
                                             
      supplemental operating activities
                                             
      cash paid for amounts included in the measurement of lease liabilities
    233,000 176,000 177,000 176,000 173,000 171,000 171,000 171,000 168,000 166,000 166,000 166,000 -483,353 161,000 162,000 161,000 -469,372 157,000                        
      supplemental non-cash investing and financing activities
                                             
      right-of-use assets acquired in exchange for operating lease liabilities
                                             
      right-of-use assets acquired in exchange for finance lease liabilities
                                             
      accrued financing costs
             257,000          174,000                      
      proceeds from development financing
          25,000,000                                  
      net increase in cash and cash equivalents
     238,239,000 -23,668,000 38,859,000 -10,400,000 -22,062,000 -21,242,000 -51,811,000 56,843,000 36,066,000 -10,429,000 15,133,000 -22,400,676 -48,778,000 39,257,000 31,925,000 5,508,874 15,381,000 -97,493,000 76,579,000 7,200,000 -2,931,000 -20,855,000 42,527,000 45,000 13,500,000 -4,164,000 3,178,000   -8,786,000 13,491,000     -4,770,000     
      cash and cash equivalents at beginning of period
     20,291,000 125,806,000 28,193,000 -24,844,131 24,869,000 -48,946,005 48,995,000 23,054,000 10,495,000 7,706,000 11,586,000 24,401,000  
      cash and cash equivalents at end of period
     238,239,000 -23,668,000 59,150,000 -10,400,000 -22,062,000 -21,242,000 73,995,000 56,843,000 36,066,000 -10,429,000 43,326,000 -47,244,807 -48,778,000 39,257,000 56,794,000 -43,437,131 15,381,000 -97,493,000 125,574,000 7,200,000 -2,931,000 -20,855,000 65,581,000 45,000 13,500,000 -4,164,000 13,673,000 3,674,000 -5,590,000 -8,786,000 21,197,000 1,015,000 -5,011,000 861,000 10,841,000 -4,770,000 8,354,000 -14,340,000 22,342,000  
      unsettled stock option exercise
                                             
      accrued costs for other assets
                                             
      supplemental non-cash financing activities
                                             
      unsettled stock option exercise proceeds
                                             
      net accretion and amortization of investments in marketable securities
       -1,318,000 -591,000 -315,000 -99,000 131,000 94,000 117,000 230,000 196,000 239,896 66,000 -101,000 -205,000 1,906,763 -585,000 -780,000 -544,000 -587,000 -581,000 -499,000 -278,000                  
      net cash (used in) investing activities
       -60,642,000                                      
      supplemental disclosure
                                             
      net cash (used in) operating activities
                                             
      unpaid financing costs
                                             
      other prepaid expenses and current assets
         1,019,000 759,000 1,077,000                                  
      issuance costs paid for issuance of common stock
         -459,000                                  
      accrued financing costs in accounts payable
                                             
      interest receivable and other current assets
             587,000 -121,000 299,000 -42,361 -436,000 168,000 310,000 204,617 216,000 -244,000 -177,000  186,000                    
      prepaid expenses
                -7,063,923 561,000    -787,000 -3,054,000 -2,233,000 -801,000 338,000 -764,000 -159,000 160,000 -242,000 2,000 241,000 -565,000 -295,000 58,000 41,000 363,000 -495,000 367,000 628,000 -589,000 73,000 401,000 -1,512,000 -331,000 
      accrued liabilities
             2,575,000 1,374,000 -3,458,000 2,869,187 1,382,000 -1,193,000 -3,061,000 -3,363,669 3,221,000 582,000 -440,000 205,000 2,054,000 4,972,000 -781,000 1,873,000 286,000 40,000 -812,000 1,391,000 63,000 163,000 -602,000 -681,000 853,000 166,000 -390,000 -602,000 1,214,000 447,000 830,000 189,000 
      prepaid research and development expenses and other prepaid assets
              59,000 -2,852,000    1,951,000                          
      cash from financing activities
                -6,908                             
      accelerated vesting of stock-based compensation due to restructuring
                                             
      accrued restructuring charges
                3,096,825 -786,000 -838,000 -1,476,000                          
      proceeds from sale of marketable securities
                    -3,976,020 3,980,000                      
      proceeds from issuance of common stock, net of issuance costs
                    -107,638,254 -174,000 107,920,000 135,520,000 -151,000 91,223,000 9,364,000        4,263,000      
      supplemental disclosures
                                             
      operating lease right-of-use assets obtained in exchange for lease liabilities
                                             
      accelerated vesting of stock-based compensation expense due to restructuring
                                             
      non-cash interest associated with debt discount accretion
                        56,000 92,000 98,000 107,000 112,000 120,000 124,000 123,000   76,000 66,000 50,000 36,000 54,000 53,000 42,000 49,000  
      loss on extinguishment of debt
                                           
      change in fair value of warrant liability
                        -1,031,000 87,000 4,654,000 777,000 1,798,000 1,064,000 2,134,000 -32,000 -82,000 359,000 -320,000 -136,000 -1,083,000 -5,327,000 -4,575,000 4,947,000 255,000 -2,750,000 4,784,000  
      gain on extinguishment of warrant liability
                                            
      accretion of tenant improvement allowance
                        -109,000 -93,000                    
      receivable from collaboration
                                           
      prepaid research and development and other prepaid expenses
                                             
      accrued restructuring
                                             
      accrued interest payable
                        -37,000 -6,000 -6,000 -6,000 -5,000 -6,000 -6,000    34,000 71,000 23,000 15,000 27,000 28,000 26,000 26,000 60,000 
      proceeds from issuance of common stock upon exercise of warrants
                        1,513,000 381,000 656,000                  
      repayment of facility loan principal
                        -5,698,000 -829,000 -810,000 -793,000 -775,000 -759,000              
      payment of fees to extinguish facility loan
                                           
      cash paid for interest
                        108,000 123,000         219,000 122,000 93,000 101,000 107,000 109,000 110,000 109,000  
      issuance of common stock upon warrant exercises
                        4,179,000 2,103,000 3,097,000         196,000 1,317,000      
      lessor funded lease incentives included in property and equipment
                                             
      accrued property and equipment
                                             
      lessor funded lease incentives included in other current assets
                                            
      other current assets
                           -147,000 3,000 -105,000 16,000 -12,000              
      net change in accrued financing costs
                                             
      accounts receivable
                           5,000,000                  
      accretion and amortization of marketable securities
                             -51,000 5,000 -1,000              
      amortization of premium on marketable securities
                                -3,000 -5,000 27,000 106,000 164,000 119,000 61,000 167,000 164,000 111,000 107,000 71,000  
      proceeds from facility loan
                                           
      proceeds from issuance of common stock and warrants, net of issuance costs
                                        23,028,000 2,402,000  
      supplemental non-cash investing and financing activites
                                             
      issuance of common stock warrants to lenders
                                             
      stock based compensation expense
                                 667,000            
      contract receivables
                                    17,000 -17,000 211,000 -197,000 -4,000 158,000 -58,000 -110,000 
      accrued interest receivable
                                 -3,000 77,000 90,000 23,000 -126,000 116,000 -63,000 87,000 -89,000 -44,000 -22,000 -68,000 
      other liabilities
                                 -2,000   1,000 2,000 2,000 1,000 3,000 4,000 3,000 3,000  
      repayment of loan principal
                                      -384,000 -374,000      
      proceeds from issuance of common stock upon warrant exercises
                                     426,000      
      net decrease in cash and cash equivalents
                                    1,015,000   -745,000   -14,340,000 -2,059,000  
      non-employee stock-based compensation expense
                                   3,000 -1,000 -6,000 28,000 3,000 2,000 1,000 2,000  
      employee and director stock-based compensation expense
                                   556,000 614,000 562,000 585,000 705,000 272,000 223,000 75,000 714,000 826,000 
      non-cash interest associated with debt discount and final payment accretion
                                   113,000          
      proceeds from sales and maturities of marketable securities
                                   20,631,000 7,227,000 3,450,000 13,312,000 7,716,000 5,450,000     
      loss on sale of property and equipment
                                             
      proceeds from issuance of common stock upon exercise of stock options
                                             
      supplemental disclosure of cash flow information
                                             
      noncash issuance costs incurred in common stock financing
                                        453,000  
      reclassification of incentive awards to equity
                                        1,000    
      proceeds from issuance of common stock and warrants, net of costs
                                             
      payment of loan principal
                                             
      proceeds from issuance of common stock upon exercise of employee stock options
                                        2,000    
      issuance of common stock warrants
                                          443,000  
      fixed assets in accrued expenses
                                           28,000  
      amortization of notes payable conversion option
                                            
      gain on sale of property and equipment
                                        1,000   -207,000 
      proceeds from sale of property and equipment
                                             
      repurchase of preferred stock
                                            
      financing costs in accrued expenses
                                             
      fair value of forward contract
                                             
      issuance of common stock warrants to common stockholders
                                             
      conversion of preferred shares into common stock
                                             
      issuance of common stock for debt extinguishment
                                            
      issuance of common stock warrants-lenders
                                             
      issuance of common stock warrants-common stock
                                             
      issuance of common stock upon cashless warrant exercise
                                         377,000 55,000  
      proceeds from sales of marketable securities
                                          1,649,000 582,000  
      proceeds from the sale of property and equipment
                                             
      principal payments on equipment loans
                                             
      net increase(decrease) in cash and cash equivalents
                                             
      cash and cash equivalents at beginning of year
                                            
      cash and cash equivalents at end of year
                                            -7,679,000 
      interest paid
                                             
      conversion of preferred stock into common stock
                                             
      non-cash interest associated with discount accretion
                                             
      deferred rent
                                             
      deferred revenue
                                             
      proceeds from issuance of commons stock and warrants, net of issuance costs
                                             
    The information provided in this report is taken from www.sec.gov and many other data providers. While we have conducted our best efforts to ensure that the parsed data is accurate, we cannot guarantee its accuracy. Please use caution and understand that any consequences of its use are your own responsibility.